CN104012541A - Fungicidal composition containing diflumetorim and triazole - Google Patents
Fungicidal composition containing diflumetorim and triazole Download PDFInfo
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- CN104012541A CN104012541A CN201310063912.9A CN201310063912A CN104012541A CN 104012541 A CN104012541 A CN 104012541A CN 201310063912 A CN201310063912 A CN 201310063912A CN 104012541 A CN104012541 A CN 104012541A
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Abstract
The invention discloses a fungicidal composition containing diflumetorim and triazole. Effective ingredients of the fungicidal composition consist of an active ingredient A and an active ingredient B, wherein the active ingredient A is selected from diflumetorim, the active ingredient B is any compound selected from triflumizole, tetraconazole, diniconazole, triticonazole, ipconazole and prothioconazole, and the weight ratio of the active ingredient A to the active ingredient B is (1: 80) to (80: 1). The composition disclosed by the invention has relatively high activity to various diseases of a variety of crops and has obvious synergism, and the anti-fungal spectrum is enlarged; the composition has the characteristics of small dosage, rainwater washing resistance and obvious synergism.
Description
Technical field
The invention belongs to technical field of pesticide, relate to the application of a kind of bactericidal composition that contains fluorine mepanipyrim and triazole type on corps diseases.
Background technology
Fluorine mepanipyrim: any conk phase that mechanism of action fluorine mepanipyrim forms from conidia germination to conidiophore, can suppress immediately growth.Its chemical constitution is different from existing bactericide, and same triazole type, dithiocarbamate, benzimidazole and other classes comprise that antibiotic etc. is without cross resistance, thus its to sensitivity or resistance cause of disease because all there being excellent activity.
Fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole, kind bacterium azoles or prothioconazoles all belong to triazole bactericidal agent, are widely used in the disease of crops.
Yet in the real process of agricultural production, preventing and treating the problem that disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of sterilization is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor's research, discovery can produce good synergistic effect by fluorine mepanipyrim and fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole, kind bacterium azoles or prothioconazoles after composite, and not yet open about fluorine mepanipyrim and the composite relevant report of fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole, kind bacterium azoles or prothioconazoles.
Summary of the invention
The object of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect the is good bactericidal composition that contains fluorine mepanipyrim and triazole type.
The bactericidal composition that contains fluorine mepanipyrim and triazole type that the present invention proposes, active ingredient is active components A and active component B, activity is divided into A and active component B weight ratio is 1 ︰ 80 ~ 80 ︰ 1, described active components A is selected from fluorine mepanipyrim, active component B is selected from a kind of in fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole, kind bacterium azoles or prothioconazoles, and active components A and the preferred weight ratio of active component B are 1 ︰ 50 ~ 50 ︰ 1; More preferably the weight ratio of fluorine mepanipyrim and fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole or kind bacterium azoles is 1 ︰ 20 ~ 20 ︰ 1, and the weight ratio of fluorine mepanipyrim and prothioconazoles is 1 ︰ 25 ~ 15 ︰ 1; The weight ratio that most preferably is fluorine mepanipyrim and fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole or kind bacterium azoles is 1 ︰ 9 ~ 9 ︰ 1; The weight ratio of fluorine mepanipyrim and prothioconazoles is 1 ︰ 14 ~ 4 ︰ 1.
The bactericidal composition that contains fluorine mepanipyrim and triazole type that the present invention proposes is for preventing and treating the purposes of disease on crops, and described crops comprise cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flowers crop, medicinal crop, raw material crop, green manure pasture crop.
Described disease comprises powdery mildew, scab, rust, shot hole, smut, leaf spot, stem wilt, spot defoliation, anthrachose of grape, anthracnose, banded sclerotial blight, bakanae disease, numb pinta, rice blast, fusarium wilt, net blotch, moire disease, stalk break, gray mold, black spot, brown spot or balck shank.
The weight ratio of active components A, active component B is 1 ︰ 80 ~ 80 ︰ 1.Conventionally in composition, the weight percentage of active component is gross weight 0.5%～90%, is preferably 5%～80%.According to different preparation types, active component content scope is different.Conventionally, liquid preparation contains 1%～70% active substance by weight, is preferably 5%～50%; Solid pharmaceutical preparation contains 5%～80% active substance by weight, is preferably 10%～80%.
In bactericidal composition of the present invention, at least contain a kind of surfactant, the dispersion of active component in water while being beneficial to use.Surface-active contents is 5%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
Bactericidal composition of the present invention can be by user before use through dilution or directly use.Its preparation can be prepared by common processing method known in those skilled in the art, after being about to active substance and mixing with liquid flux or solid carrier, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer, disintegrant, antifreeze etc.
Bactericidal composition of the present invention, can be processed on demand acceptable formulation in any sterilization, wherein more preferably formulation is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspending agent, fluorine mepanipyrim and prothioconazoles can be made missible oil, and fluorine mepanipyrim and fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole, kind bacterium azoles or prothioconazoles all can be done seed coat agent.
When making wetting powder, composition comprises following constituent content: active components A 1% ~ 80%, active component B1% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
When making water dispersible granules, composition comprises following constituent content: active components A 1% ~ 80%, active component B1% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
When making suspending agent, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
When making suspension emulsion, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, solvent 1% ~ 15%, thickener 0 ~ 2%, emulsifier 2% ~ 12%, antifreeze 0 ~ 8%, deionized water add to 100%.
When making aqueous emulsion, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 1% ~ 15%, antifreeze 0 ~ 8%, thickener 0 ~ 2%, defoamer 0.01% ~ 2%, deionized water are supplied surplus.
When making microemulsion, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 3% ~ 25%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water are supplied surplus.
When making microcapsule suspending agent, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, organic solvent 1% ~ 10%, emulsifier 1% ~ 7%, defoamer 0.01% ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
When making microcapsule suspension-suspending agent, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, organic solvent 1% ~ 15%, emulsifier 1% ~ 6%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%;
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspending agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) fluorine mepanipyrim and fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole, kind bacterium azoles or prothioconazoles composite after, there is obvious synergy and lasting effect; (2) disease on cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flowers crop, medicinal crop, raw material crop, green manure pasture crop is all had to greater activity; (3) reduce agricultural chemicals dosage, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution; (4), to person poultry safety, Environmental compatibility is good; And preparation adhesion strength strengthens, resistance of rainwater washing against.
Embodiment
Below in conjunction with embodiment, to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Embodiment 1～16 wetting powder
Fluorine mepanipyrim, active component B, dispersant, wetting agent, filler are mixed in mixed cylinder, after airslide disintegrating mill is pulverized, mix again, can make wetting powder product of the present invention, specifically in Table 1.
Table 1 embodiment 1～16 each component and weight portion
Embodiment 17～30 water dispersible granules
Fluorine mepanipyrim, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained to the particle diameter needing through air-flow crushing together, then add other auxiliary agents such as binding agent (can add and can not add), obtain the materials of granulating.By item quantitatively send in fluidized bed granulation dryer through granulation and dry after, can make water dispersible granules product of the present invention, specifically in Table 2.
Table 2 embodiment 17～30 each component and weight portions
Embodiment 31～44 suspending agents
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), through high speed shear, mix, add fluorine mepanipyrim, active component B, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, surplus is supplied by deionized water, can make suspending agent product of the present invention, specifically in Table 3.
Table 3 embodiment 31～44 each component and weight portions
Embodiment 45～52 suspension emulsions
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add fluorine mepanipyrim, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make fluorine mepanipyrim suspending agent, then by active component B, solvent, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, surplus is supplied by deionized water, make suspension emulsion product of the present invention, specifically in Table 4.
Table 4 embodiment 45～52 each component and weight portions
Embodiment 53～64 aqueous emulsions
Fluorine mepanipyrim, active component B, solvent, emulsifier are added together, make to be dissolved into even oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, become homogeneous water.Under high-speed stirred, water is added to oil phase, surplus is supplied by deionized water; Can make aqueous emulsion product of the present invention, specifically in Table 5.
Table 5 embodiment 53～64 each component and weight portions
Fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole, kind bacterium azoles or prothioconazoles in table 1 ~ 5 are exchanged, can make novel formulation.
Embodiment 65～67 microemulsions
Fluorine mepanipyrim, active component B, solvent, emulsifier, antifreeze (can add and can not add), defoamer are fully mixed into the oil phase of homogeneous transparent, under agitation slowly add deionized water, form WO emulsion, again through agitating heating, make it rapid phase inversion and become oil-in-water type, be chilled to room temperature and make it to reach balance, after filtration, surplus is supplied by deionized water; Can make microemulsion product of the present invention, specifically in Table 6.
Table 6 embodiment 65～67 each component and weight portions
Embodiment 68,69 microcapsule suspending agents
By fluorine mepanipyrim, active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, under shearing condition, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent, dispersant, surplus is supplied by deionized water, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in Table 7.
Table 7 embodiment 68,69 each component and weight portions
Embodiment 70,71 microcapsule suspensions-suspending agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent under shearing condition, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add fluorine mepanipyrim, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make suspending agent, then suspending agent is joined in the aqueous phase solution of micro-capsule suspension, deionized water is supplied surplus, make the finely disseminated microcapsule suspension-suspending agent of present composition product, specifically in Table 8.
Table 8 embodiment 70,71 each component and weight portions
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR < 0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR > 1.5 is synergistic effect, on this basis, then carries out field trial.
Test method: after the effective inhibition concentration scope of each medicament is determined in prerun, medicament is established respectively 5 dosage by active constituent content and processed, and establishes clear water contrast.With reference to < < farm-chemical indoor determination test rule bactericide > >, carry out, adopt mycelial growth rate method to measure the virulence of medicament to crop germ.After 72h, by right-angled intersection method, measure colony diameter, calculate respectively process net growth,
Mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value to (x), with method of least squares, tries to achieve virulence regression equation (y=a+bx), and calculates thus the EC of every kind of medicament
50value.According to Wadley method, calculate the different proportioning synergy ratio (SR) of two medicaments, SR < 0.5 is antagonism simultaneously, and 0.5≤SR≤1.5 are summation action, and SR > 1.5 is synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and active component B shared ratio in combination;
A is fluorine mepanipyrim;
B is selected from a kind of in fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole, kind bacterium azoles or prothioconazoles.
Virulence experiment part: test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Application Example two:
For trying disease: powdery mildew of cucumber;
Experimental scheme: effective inhibition concentration scope of determining fluorine mepanipyrim and the two different proportioning mixture of fluorine bacterium azoles through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to powdery mildew of cucumber of table 9 fluorine mepanipyrim and fluorine bacterium azoles
As shown in Table 9, the composite proportioning of preventing and treating powdery mildew of cucumber of fluorine mepanipyrim and fluorine bacterium azoles is when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, illustrating that both are mixed within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine mepanipyrim and fluorine bacterium azoles is in 1:20～20: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.85, when fluorine mepanipyrim and fluorine bacterium azoles weight ratio are 2:3, synergy ratio is maximum, and synergistic effect is the most obvious.Through applicant, test discovery, the proportioning of fluorine mepanipyrim and fluorine bacterium azoles is 20 ︰ 1, 19 ︰ 1, 18 ︰ 1, 17 ︰ 1, 16 ︰ 1, 15 ︰ 1, 14 ︰ 1, 13 ︰ 1, 12 ︰ 1, 11 ︰ 1, 10 ︰ 1, 9 ︰ 1, 8 ︰ 1, 7 ︰ 1, 6 ︰ 1, 5 ︰ 1, 4 ︰ 1, 3 ︰ 1, 2 ︰ 1, 1 ︰ 1, 1 ︰ 2, 1 ︰ 3, 1 ︰ 4, 1 ︰ 5, 1 ︰ 6, 1 ︰ 7, 1 ︰ 8, 1 ︰ 9, 1 ︰ 10, 1 ︰ 11, 1 ︰ 12, 1 ︰ 13, 1 ︰ 14, 1 ︰ 15, 1 ︰ 16, 1 ︰ 17, 1 ︰ 18, 1 ︰ 19, during 1 ︰ 20 to powdery mildew, scab, rust, shot hole, smut, leaf spot, stem wilt, spot defoliation, anthrachose of grape, anthracnose, banded sclerotial blight, bakanae disease, fiber crops pinta, rice blast, fusarium wilt, net blotch, moire disease, stalk break, gray mold, black spot, the control of brown spot or balck shank has obvious synergistic effect, synergy ratio is all more than 1.5.
Application Example three:
For trying disease: grape powdery mildew;
Experimental scheme: effective inhibition concentration scope of determining the two different proportioning mixture of fluorine mepanipyrim and tetraconazole through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to grape powdery mildew of table 10 fluorine mepanipyrim and tetraconazole
As shown in Table 10, the proportioning of the composite control grape powdery mildew of fluorine mepanipyrim and tetraconazole is when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, illustrating that both are mixed within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine mepanipyrim and tetraconazole is in 1:20～20: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.90, when fluorine mepanipyrim and tetraconazole weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.Through applicant, test discovery, the proportioning of fluorine mepanipyrim and tetraconazole is 20 ︰ 1, 19 ︰ 1, 18 ︰ 1, 17 ︰ 1, 16 ︰ 1, 15 ︰ 1, 14 ︰ 1, 13 ︰ 1, 12 ︰ 1, 11 ︰ 1, 10 ︰ 1, 9 ︰ 1, 8 ︰ 1, 7 ︰ 1, 6 ︰ 1, 5 ︰ 1, 4 ︰ 1, 3 ︰ 1, 2 ︰ 1, 1 ︰ 1, 1 ︰ 2, 1 ︰ 3, 1 ︰ 4, 1 ︰ 5, 1 ︰ 6, 1 ︰ 7, 1 ︰ 8, 1 ︰ 9, 1 ︰ 10, 1 ︰ 11, 1 ︰ 12, 1 ︰ 13, 1 ︰ 14, 1 ︰ 15, 1 ︰ 16, 1 ︰ 17, 1 ︰ 18, 1 ︰ 19, during 1 ︰ 20 to powdery mildew, scab, rust, shot hole, smut, leaf spot, stem wilt, spot defoliation, anthrachose of grape, anthracnose, banded sclerotial blight, bakanae disease, fiber crops pinta, rice blast, fusarium wilt, net blotch, moire disease, stalk break, gray mold, black spot, the control of brown spot or balck shank has obvious synergistic effect, synergy ratio is all more than 1.5.
Application Example four:
For trying disease: wheat powdery mildew;
Experimental scheme: effective inhibition concentration scope of determining fluorine mepanipyrim and the two different proportioning mixture of alkene azoles alcohol through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to wheat powdery mildew of table 11 fluorine mepanipyrim and alkene azoles alcohol
As shown in Table 11, the proportioning of fluorine mepanipyrim and the composite control wheat powdery mildew of alkene azoles alcohol is when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, illustrating that both are mixed within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine mepanipyrim and alkene azoles alcohol is in 1:20～20: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.85, when fluorine mepanipyrim and alkene azoles alcohol weight ratio are 2:3, synergy ratio is maximum, and synergistic effect is the most obvious.Through applicant, test discovery, the proportioning of fluorine mepanipyrim and alkene azoles alcohol is 20 ︰ 1, 19 ︰ 1, 18 ︰ 1, 17 ︰ 1, 16 ︰ 1, 15 ︰ 1, 14 ︰ 1, 13 ︰ 1, 12 ︰ 1, 11 ︰ 1, 10 ︰ 1, 9 ︰ 1, 8 ︰ 1, 7 ︰ 1, 6 ︰ 1, 5 ︰ 1, 4 ︰ 1, 3 ︰ 1, 2 ︰ 1, 1 ︰ 1, 1 ︰ 2, 1 ︰ 3, 1 ︰ 4, 1 ︰ 5, 1 ︰ 6, 1 ︰ 7, 1 ︰ 8, 1 ︰ 9, 1 ︰ 10, 1 ︰ 11, 1 ︰ 12, 1 ︰ 13, 1 ︰ 14, 1 ︰ 15, 1 ︰ 16, 1 ︰ 17, 1 ︰ 18, 1 ︰ 19, during 1 ︰ 20 to powdery mildew, scab, rust, shot hole, smut, leaf spot, stem wilt, spot defoliation, anthrachose of grape, anthracnose, banded sclerotial blight, bakanae disease, fiber crops pinta, rice blast, fusarium wilt, net blotch, moire disease, stalk break, gray mold, black spot, the control of brown spot or balck shank has obvious synergistic effect, synergy ratio is all more than 1.5.
Application Example five:
For trying disease: wheat rust;
Experimental scheme: effective inhibition concentration scope of determining the two different proportioning mixture of fluorine mepanipyrim and triticonazole through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to wheat rust of table 12 fluorine mepanipyrim and triticonazole
As shown in Table 12, the composite proportioning of preventing and treating wheat rust of fluorine mepanipyrim and triticonazole is when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, illustrating that both are mixed within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine mepanipyrim and triticonazole is in 1:20～20: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.90, when fluorine mepanipyrim and triticonazole weight ratio are 1:2, synergy ratio is maximum, and synergistic effect is the most obvious.Through applicant, test discovery, the proportioning of fluorine mepanipyrim and triticonazole is 20 ︰ 1, 19 ︰ 1, 18 ︰ 1, 17 ︰ 1, 16 ︰ 1, 15 ︰ 1, 14 ︰ 1, 13 ︰ 1, 12 ︰ 1, 11 ︰ 1, 10 ︰ 1, 9 ︰ 1, 8 ︰ 1, 7 ︰ 1, 6 ︰ 1, 5 ︰ 1, 4 ︰ 1, 3 ︰ 1, 2 ︰ 1, 1 ︰ 1, 1 ︰ 2, 1 ︰ 3, 1 ︰ 4, 1 ︰ 5, 1 ︰ 6, 1 ︰ 7, 1 ︰ 8, 1 ︰ 9, 1 ︰ 10, 1 ︰ 11, 1 ︰ 12, 1 ︰ 13, 1 ︰ 14, 1 ︰ 15, 1 ︰ 16, 1 ︰ 17, 1 ︰ 18, 1 ︰ 19, during 1 ︰ 20 to powdery mildew, scab, rust, shot hole, smut, leaf spot, stem wilt, spot defoliation, anthrachose of grape, anthracnose, banded sclerotial blight, bakanae disease, fiber crops pinta, rice blast, fusarium wilt, net blotch, moire disease, stalk break, gray mold, black spot, the control of brown spot or balck shank has obvious synergistic effect, synergy ratio is all more than 1.5.
Application Example six:
For trying disease: rice blast;
Experimental scheme: determine fluorine mepanipyrim and effective inhibition concentration scope of planting the two different proportioning mixture of bacterium azoles through preliminary experiment.
Toxicity test result
Table 13 fluorine mepanipyrim and the composite toxicity test analysis of results table to rice blast of kind bacterium azoles
As shown in Table 13, the proportioning of fluorine mepanipyrim and the composite control rice blast of kind bacterium azoles is when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, illustrating that both are mixed within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine mepanipyrim and kind bacterium azoles is in 1:20～20: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.90, when fluorine mepanipyrim is 2:1 with kind bacterium azoles weight ratio, synergy ratio is maximum, and synergistic effect is the most obvious.Through applicant, test discovery, fluorine mepanipyrim is 20 ︰ 1 with the proportioning of planting bacterium azoles, 19 ︰ 1, 18 ︰ 1, 17 ︰ 1, 16 ︰ 1, 15 ︰ 1, 14 ︰ 1, 13 ︰ 1, 12 ︰ 1, 11 ︰ 1, 10 ︰ 1, 9 ︰ 1, 8 ︰ 1, 7 ︰ 1, 6 ︰ 1, 5 ︰ 1, 4 ︰ 1, 3 ︰ 1, 2 ︰ 1, 1 ︰ 1, 1 ︰ 2, 1 ︰ 3, 1 ︰ 4, 1 ︰ 5, 1 ︰ 6, 1 ︰ 7, 1 ︰ 8, 1 ︰ 9, 1 ︰ 10, 1 ︰ 11, 1 ︰ 12, 1 ︰ 13, 1 ︰ 14, 1 ︰ 15, 1 ︰ 16, 1 ︰ 17, 1 ︰ 18, 1 ︰ 19, during 1 ︰ 20 to powdery mildew, scab, rust, shot hole, smut, leaf spot, stem wilt, spot defoliation, anthrachose of grape, anthracnose, banded sclerotial blight, bakanae disease, fiber crops pinta, rice blast, fusarium wilt, net blotch, moire disease, stalk break, gray mold, black spot, the control of brown spot or balck shank has obvious synergistic effect, synergy ratio is all more than 1.5.
Application Example seven:
For trying disease: wheat rust;
Experimental scheme: effective inhibition concentration scope of determining the two different proportioning mixture of fluorine mepanipyrim and prothioconazoles through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to wheat rust of table 14 fluorine mepanipyrim and prothioconazoles
As shown in Table 14, the composite proportioning of preventing and treating wheat rust of fluorine mepanipyrim and prothioconazoles is when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, illustrating that both are mixed within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine mepanipyrim and prothioconazoles is in 1:25～15: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.85, when fluorine mepanipyrim and prothioconazoles weight ratio are 1:4, synergy ratio is maximum, and synergistic effect is the most obvious.Through applicant, test discovery, the proportioning of fluorine mepanipyrim and prothioconazoles is 15 ︰ 1, 14 ︰ 1, 13 ︰ 1, 12 ︰ 1, 11 ︰ 1, 10 ︰ 1, 9 ︰ 1, 8 ︰ 1, 7 ︰ 1, 6 ︰ 1, 5 ︰ 1, 4 ︰ 1, 3 ︰ 1, 2 ︰ 1, 1 ︰ 1, 1 ︰ 2, 1 ︰ 3, 1 ︰ 4, 1 ︰ 5, 1 ︰ 6, 1 ︰ 7, 1 ︰ 8, 1 ︰ 9, 1 ︰ 10, 1 ︰ 11, 1 ︰ 12, 1 ︰ 13, 1 ︰ 14, 1 ︰ 15, 1 ︰ 16, 1 ︰ 17, 1 ︰ 18, 1 ︰ 19, 1 ︰ 20, 1 ︰ 21, 1 ︰ 22, 1 ︰ 23, 1 ︰ 24, during 1 ︰ 25 to powdery mildew, scab, rust, shot hole, smut, leaf spot, stem wilt, spot defoliation, anthrachose of grape, anthracnose, banded sclerotial blight, bakanae disease, fiber crops pinta, rice blast, fusarium wilt, net blotch, moire disease, stalk break, gray mold, black spot, the control of brown spot or balck shank has obvious synergistic effect, synergy ratio is all more than 1.5.
Effect experiment part: test medicine is researched and developed, provided by Shaanxi Mei Bang agricultural chemicals Co., Ltd, contrast medicament 10% fluorine mepanipyrim missible oil (autogamy), 30% triflumizole wettable powder (commercial), 4% tetraconazole aqueous emulsion (autogamy), 12.5% alkene azoles alcohol wetting powder (commercial), 28% triticonazole suspension seed-coating agent (commercial), 25 grams per liter kind bacterium azoles suspension seed-coating agents (commercial), 25% prothioconazoles missible oil (commercial).The investigation state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, dispenser is 1 time altogether.
Application Example octafluoro mepanipyrim and active component B and the composite powdery mildew of cucumber test of pesticide effectiveness of preventing and treating thereof
This test arrangement is in Weinan City suburb, Shaanxi Province, and investigation powdery mildew of cucumber disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 30 days.Result of the test is as follows:
Table 15 fluorine mepanipyrim and active component B and the composite powdery mildew of cucumber test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 15, after fluorine mepanipyrim and active component B are composite, can effectively prevent and treat powdery mildew of cucumber, control efficiency, all higher than 96%, is better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine fluorine mepanipyrims and active component B and the composite wheat rust test of pesticide effectiveness of preventing and treating thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation wheat rust disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 30 days.Result of the test is as follows:
Table 16 fluorine mepanipyrim and active component B and the composite wheat rust test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 16, after fluorine mepanipyrim and active component B are composite, can effectively prevent and treat wheat rust, through applicant, test and find that fluorine mepanipyrim and active component B also can effectively prevent and treat wheat smut, wheat powdery mildew or wheat sharp eyespot after composite, control efficiency is all higher than 96%, the preventive effect that is better than single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten fluorine mepanipyrims and active component B and the composite control rice blast test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, and investigation rice blast disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 30 days.Result of the test is as follows:
Table 17 fluorine mepanipyrim and active component B and the composite control rice blast test of pesticide effectiveness thereof
As can be seen from Table 17, after fluorine mepanipyrim and active component B are composite, can effectively prevent and treat rice blast, through applicant, test and find that fluorine mepanipyrim and active component B also can effectively prevent and treat the numb pinta of rice sheath blight disease, bakanae disease of rice or paddy rice after composite, control efficiency is all higher than 97%, the preventive effect that is better than single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 fluorine mepanipyrims and active component B and the composite wheat smut test of pesticide effectiveness of preventing and treating thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation wheat smut disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 30 days.Result of the test is as follows:
Table 18 fluorine mepanipyrim and active component B and the composite wheat smut test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 18, after fluorine mepanipyrim and active component B are composite, can effectively prevent and treat wheat smut, through applicant, test and find that fluorine mepanipyrim and active component B also can effectively prevent and treat wheat powdery mildew, wheat sharp eyespot or wheat rust after composite, control efficiency is all higher than 97%, the preventive effect that is better than single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten difluoro mepanipyrims and active component B and the composite rice sheath blight disease test of pesticide effectiveness of preventing and treating thereof
This test arrangement is at Shaanxi Province's Hanzhong City, and investigation rice sheath blight disease disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 30 days.Result of the test is as follows:
Table 19 fluorine mepanipyrim and active component B and the composite rice sheath blight disease test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 19, after fluorine mepanipyrim and active component B are composite, can effectively prevent and treat rice sheath blight disease, through applicant, test and find that fluorine mepanipyrim and active component B also can effectively prevent and treat the numb pinta of rice blast, bakanae disease of rice or paddy rice after composite, control efficiency is all higher than 97%, the preventive effect that is better than single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten trifluoro mepanipyrims and active component B and the composite control pear scab test of pesticide effectiveness thereof
This test arrangement is in Weinan City Dali County, Shaanxi Province, and investigation pear scab disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 7 days, 14 days, 30 days.Result of the test is as follows:
Table 20 fluorine mepanipyrim and active component B and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 20, after fluorine mepanipyrim and active component B are composite, can effectively prevent and treat pear scab, through applicant, test and find that fluorine mepanipyrim and active component B also can effectively prevent and treat pear tree powdery mildew, pear tree rust or pear tree spot defoliation after composite, control efficiency is all higher than 97%, the preventive effect that is better than single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After through different local throughout the country tests, draw, fluorine mepanipyrim and fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole, kind bacterium azoles or prothioconazoles composite rear to the preventive effect of the Common Diseases such as the powdery mildew in various crop, scab, rust, shot hole, smut, leaf spot, stem wilt, spot defoliation, anthrachose of grape, anthracnose, banded sclerotial blight, bakanae disease, numb pinta, rice blast, fusarium wilt, net blotch, moire disease, stalk break, gray mold, black spot, brown spot or balck shank all more than 96%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. a bactericidal composition that contains fluorine mepanipyrim and triazole type, effective active composition is active components A and active component B, it is characterized in that: active components A and active component B weight ratio are 1 ︰ 80 ~ 80 ︰ 1, described active components A is selected from fluorine mepanipyrim, and active component B is selected from a kind of in fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole, kind bacterium azoles or prothioconazoles.
2. the bactericidal composition that contains fluorine mepanipyrim and triazole type according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 50 ~ 50 ︰ 1.
3. the bactericidal composition that contains fluorine mepanipyrim and triazole type according to claim 2, is characterized in that:
The weight ratio of fluorine mepanipyrim and fluorine bacterium azoles, tetraconazole, alkene azoles alcohol, triticonazole or kind bacterium azoles is 1 ︰ 20 ~ 20 ︰ 1;
The weight ratio of fluorine mepanipyrim and prothioconazoles is 1 ︰ 25 ~ 15 ︰ 1.
4. according to the bactericidal composition that contains fluorine mepanipyrim and triazole type described in any one in claims 1 to 3, it is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent or microcapsule suspension-suspending agent.
5. the bactericidal composition that contains fluorine mepanipyrim and triazole type according to claim 4 is for preventing and treating the purposes of disease on crops.
6. purposes according to claim 5, is characterized in that: described disease comprises powdery mildew, scab, rust, shot hole, smut, leaf spot, stem wilt, spot defoliation, anthrachose of grape, anthracnose, banded sclerotial blight, bakanae disease, numb pinta, rice blast, fusarium wilt, net blotch, moire disease, stalk break, gray mold, black spot, brown spot or balck shank.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105360136A (en) * | 2015-11-06 | 2016-03-02 | 南京华洲药业有限公司 | Sterilization composition containing mepanipyrim and diniconazole and application thereof |
| CN105360144A (en) * | 2015-11-06 | 2016-03-02 | 南京华洲药业有限公司 | Sterilization composition containing mepanipyrim and benthiavalicarb-isopropyl and application thereof |
| CN106508933A (en) * | 2015-09-15 | 2017-03-22 | 南京华洲药业有限公司 | Sterilization composition containing benthiavalicarb-isopropyl and mepanipyrim |
| CN107549175A (en) * | 2017-08-31 | 2018-01-09 | 陕西康禾立丰生物科技药业有限公司 | A kind of bactericidal composition of metsulfovax containing isopropyl and triazole type |
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| EP0432894A1 (en) * | 1989-12-07 | 1991-06-19 | Ube Industries, Ltd. | Fungicidal composition |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
| CN102106349A (en) * | 2009-12-23 | 2011-06-29 | 中国中化股份有限公司 | Antifungal composition containing tebuconazole and pyrimidine compound |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP0432894A1 (en) * | 1989-12-07 | 1991-06-19 | Ube Industries, Ltd. | Fungicidal composition |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
| CN102106349A (en) * | 2009-12-23 | 2011-06-29 | 中国中化股份有限公司 | Antifungal composition containing tebuconazole and pyrimidine compound |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106508933A (en) * | 2015-09-15 | 2017-03-22 | 南京华洲药业有限公司 | Sterilization composition containing benthiavalicarb-isopropyl and mepanipyrim |
| CN105360136A (en) * | 2015-11-06 | 2016-03-02 | 南京华洲药业有限公司 | Sterilization composition containing mepanipyrim and diniconazole and application thereof |
| CN105360144A (en) * | 2015-11-06 | 2016-03-02 | 南京华洲药业有限公司 | Sterilization composition containing mepanipyrim and benthiavalicarb-isopropyl and application thereof |
| CN107549175A (en) * | 2017-08-31 | 2018-01-09 | 陕西康禾立丰生物科技药业有限公司 | A kind of bactericidal composition of metsulfovax containing isopropyl and triazole type |
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