CN104012556A - Microbicide composition containing diflumetorim and thiocarbamate - Google Patents
Microbicide composition containing diflumetorim and thiocarbamate Download PDFInfo
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- CN104012556A CN104012556A CN201310066420.5A CN201310066420A CN104012556A CN 104012556 A CN104012556 A CN 104012556A CN 201310066420 A CN201310066420 A CN 201310066420A CN 104012556 A CN104012556 A CN 104012556A
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- fluorine mepanipyrim
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- spot
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- mepanipyrim
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- 239000000203 mixture Substances 0.000 title claims abstract description 44
- 230000003641 microbiacidal effect Effects 0.000 title abstract 4
- 229940124561 microbicide Drugs 0.000 title abstract 4
- 239000002855 microbicide agent Substances 0.000 title abstract 4
- NEKULYKCZPJMMJ-UHFFFAOYSA-N 5-chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methylpyrimidin-4-amine Chemical compound C=1C=C(OC(F)F)C=CC=1C(CC)NC1=NC=NC(C)=C1Cl NEKULYKCZPJMMJ-UHFFFAOYSA-N 0.000 title abstract 3
- GNVMUORYQLCPJZ-UHFFFAOYSA-M Thiocarbamate Chemical compound NC([S-])=O GNVMUORYQLCPJZ-UHFFFAOYSA-M 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 56
- 201000010099 disease Diseases 0.000 claims abstract description 54
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- 229910052731 fluorine Inorganic materials 0.000 claims description 81
- 239000011737 fluorine Substances 0.000 claims description 81
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims description 79
- 239000005805 Mepanipyrim Substances 0.000 claims description 78
- CIFWZNRJIBNXRE-UHFFFAOYSA-N mepanipyrim Chemical compound CC#CC1=CC(C)=NC(NC=2C=CC=CC=2)=N1 CIFWZNRJIBNXRE-UHFFFAOYSA-N 0.000 claims description 77
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- 241000233679 Peronosporaceae Species 0.000 claims description 19
- AMHNZOICSMBGDH-UHFFFAOYSA-L zineb Chemical compound [Zn+2].[S-]C(=S)NCCNC([S-])=S AMHNZOICSMBGDH-UHFFFAOYSA-L 0.000 claims description 19
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- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims description 15
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- 239000000839 emulsion Substances 0.000 claims description 13
- 206010039509 Scab Diseases 0.000 claims description 12
- 150000003558 thiocarbamic acid derivatives Chemical class 0.000 claims description 10
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- 235000012333 Vitis X labruscana Nutrition 0.000 claims description 9
- 235000014787 Vitis vinifera Nutrition 0.000 claims description 9
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- 229940079593 drug Drugs 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 6
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- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 2
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- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 description 1
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- 206010059866 Drug resistance Diseases 0.000 description 1
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- DKVNPHBNOWQYFE-UHFFFAOYSA-N carbamodithioic acid Chemical compound NC(S)=S DKVNPHBNOWQYFE-UHFFFAOYSA-N 0.000 description 1
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- 238000010790 dilution Methods 0.000 description 1
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- 125000001153 fluoro group Chemical group F* 0.000 description 1
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Abstract
The invention discloses a microbicide composition containing diflumetorim and thiocarbamate. Effective ingredients of the microbicide composition consist of an active ingredient A and an active ingredient B, wherein the active ingredient A is selected from diflumetorim, the active ingredient B is any compound selected from metiram, mancozeb, propineb and zineb, and the weight ratio of the active ingredient A to the active ingredient B is (1: 80) to (60: 1). The composition disclosed by the invention has relatively high activity to various diseases of a variety of crops and has obvious synergism, and the microbicide spectrum is enlarged; the composition has the characteristics of small dosage, rainwater washing resistance and obvious synergism.
Description
Technical field
The invention belongs to technical field of pesticide, relate to the application of a kind of bactericidal composition that contains fluorine mepanipyrim and thiocarbamates on corps diseases.
Background technology
Fluorine mepanipyrim: any conk phase that mechanism of action fluorine mepanipyrim forms from conidia germination to conidiophore, can suppress immediately growth.Its chemical constitution is different from existing bactericide, and same triazole type, dithiocarbamate, benzimidazole and other classes comprise that antibiotic etc. is without cross resistance, thus its to sensitivity or resistance cause of disease because all there being excellent activity.
Carbatene, mancozeb, Propineb or zineb all belong to common fungicide, are widely used in the disease of crops.
Yet in the real process of agricultural production, preventing and treating the problem that disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of sterilization is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor's research, discovery can produce good synergistic effect by fluorine mepanipyrim and Carbatene, mancozeb, Propineb or zineb after composite, and not yet open about fluorine mepanipyrim and the composite relevant report of Carbatene, mancozeb, Propineb or zineb.
Summary of the invention
The object of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect the is good bactericidal composition that contains fluorine mepanipyrim and thiocarbamates.
The bactericidal composition that contains fluorine mepanipyrim and thiocarbamates that the present invention proposes, active ingredient is active components A and active component B, activity is divided into A and active component B weight ratio is 1 ︰ 80 ~ 60 ︰ 1, described active components A is selected from fluorine mepanipyrim, active component B is selected from a kind of in Carbatene, mancozeb, Propineb or zineb, and active components A and the preferred weight ratio of active component B are 1 ︰ 60 ~ 40 ︰ 1; More preferably the weight ratio of fluorine mepanipyrim and Carbatene is 1 ︰ 30 ~ 10 ︰ 1, and the weight ratio of fluorine mepanipyrim and mancozeb, Propineb and zineb is 1 ︰ 35 ~ 5 ︰ 1; The weight ratio that most preferably is fluorine mepanipyrim and Carbatene is 1 ︰ 19 ~ 1 ︰ 1, and the weight ratio of fluorine mepanipyrim and mancozeb, Propineb and zineb is 1 ︰ 24 ~ 1 ︰ 4.
The bactericidal composition that contains fluorine mepanipyrim and thiocarbamates that the present invention proposes is for preventing and treating the purposes of disease on crops, and described crops comprise cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flowers crop, medicinal crop, raw material crop, green manure pasture crop.
Described disease comprises shot hole, downy mildew, scab, spot defoliation, anthracnose, brown spot, black rot, blossom rot, ring spot, mildew disease, rust, white rot, anthrachose of grape, Leucoplakia, spot blight, brown line disease, black spot, balck shank, cotton disease, epidemic disease, soft rot, leaf spot, stem wilt or damping off.
The weight ratio of active components A, active component B is 1 ︰ 80 ~ 60 ︰ 1.Conventionally in composition, the weight percentage of active component is gross weight 0.5%～90%, is preferably 5%～80%.According to different preparation types, active component content scope is different.Conventionally, liquid preparation contains 1%～70% active substance by weight, is preferably 5%～50%; Solid pharmaceutical preparation contains 5%～80% active substance by weight, is preferably 10%～80%.
In bactericidal composition of the present invention, at least contain a kind of surfactant, the dispersion of active component in water while being beneficial to use.Surface-active contents is 5%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
Bactericidal composition of the present invention can be by user before use through dilution or directly use.Its preparation can be prepared by common processing method known in those skilled in the art, after being about to active substance and mixing with liquid flux or solid carrier, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer, disintegrant, antifreeze etc.
Bactericidal composition of the present invention, can be processed on demand acceptable formulation in any sterilization, wherein more preferably formulation is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspending agent, and the optional formulation of fluorine mepanipyrim and Propineb is wetting powder and water dispersible granules in addition.
When making wetting powder, composition comprises following constituent content: active components A 0.5% ~ 60%, active component B0.5% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
When making water dispersible granules, composition comprises following constituent content: active components A 0.5% ~ 60%, active component B0.5% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
When making suspending agent, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
When making suspension emulsion, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, solvent 1% ~ 15%, thickener 0 ~ 2%, emulsifier 2% ~ 12%, antifreeze 0 ~ 8%, deionized water add to 100%.
When making aqueous emulsion, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 1% ~ 15%, antifreeze 0 ~ 8%, thickener 0 ~ 2%, defoamer 0.01% ~ 2%, deionized water are supplied surplus.
When making microemulsion, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 3% ~ 25%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water are supplied surplus.
When making microcapsule suspending agent, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, organic solvent 1% ~ 10%, emulsifier 1% ~ 7%, defoamer 0.01% ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
When making microcapsule suspension-suspending agent, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, organic solvent 1% ~ 15%, emulsifier 1% ~ 6%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%;
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspending agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) fluorine mepanipyrim and Carbatene, mancozeb, Propineb or zineb composite after, there is obvious synergy and lasting effect; (2) disease on cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flowers crop, medicinal crop, raw material crop, green manure pasture crop is all had to greater activity; (3) reduce agricultural chemicals dosage, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution; (4), to person poultry safety, Environmental compatibility is good; And preparation adhesion strength strengthens, resistance of rainwater washing against.
Embodiment
Below in conjunction with embodiment, to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Embodiment 1～13 wetting powder
Fluorine mepanipyrim, active component B, dispersant, wetting agent, filler are mixed in mixed cylinder, after airslide disintegrating mill is pulverized, mix again, can make wetting powder product of the present invention, specifically in Table 1.
Table 1 embodiment 1～13 each component and weight portion
Embodiment 14～26 water dispersible granules
Fluorine mepanipyrim, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained to the particle diameter needing through air-flow crushing together, then add other auxiliary agents such as binding agent (can add and can not add), obtain the materials of granulating.By item quantitatively send in fluidized bed granulation dryer through granulation and dry after, can make water dispersible granules product of the present invention, specifically in Table 2.
Table 2 embodiment 1426 each component and weight portions
Carbatene, mancozeb, Propineb or zineb in table 1 ~ 2 are exchanged, can make novel formulation.
Embodiment 27～36 suspending agents
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), through high speed shear, mix, add fluorine mepanipyrim, active component B, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, surplus is supplied by deionized water, can make suspending agent product of the present invention, specifically in Table 3.
Table 3 embodiment 27～36 each component and weight portions
Embodiment 37～40 suspension emulsions
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add active component B, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make the suspending agent of active component B, then by fluorine mepanipyrim, solvent, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, surplus is supplied by deionized water, make suspension emulsion product of the present invention, specifically in Table 4.
Table 4 embodiment 37～40 each component and weight portions
Embodiment 41～44 aqueous emulsions
Fluorine mepanipyrim, active component B, solvent, emulsifier are added together, make to be dissolved into even oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, become homogeneous water.Under high-speed stirred, water is added to oil phase, surplus is supplied by deionized water; Can make aqueous emulsion product of the present invention, specifically in Table 5.
Table 5 embodiment 41～44 each component and weight portions
Carbatene, mancozeb or zineb in table 3 ~ 5 are exchanged, can make novel formulation.
Embodiment 45～47 microemulsions
Fluorine mepanipyrim, active component B, solvent, emulsifier, antifreeze (can add and can not add), defoamer are fully mixed into the oil phase of homogeneous transparent, under agitation slowly add deionized water, form WO emulsion, again through agitating heating, make it rapid phase inversion and become oil-in-water type, be chilled to room temperature and make it to reach balance, after filtration, surplus is supplied by deionized water; Can make microemulsion product of the present invention, specifically in Table 6.
Table 6 embodiment 45～47 each component and weight portions
Embodiment 48,49 microcapsule suspending agents
By fluorine mepanipyrim, active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, under shearing condition, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent, dispersant, surplus is supplied by deionized water, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in Table 7.
Table 7 embodiment 48,49 each component and weight portions
Embodiment 50,51 microcapsule suspensions-suspending agent
By fluorine mepanipyrim, macromolecule cyst material, solvent, make to be dissolved into even oil phase, oil phase is joined under shearing condition in the aqueous phase solution that contains emulsifier, pH adjusting agent,
Make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add active component B, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make suspending agent, then suspending agent is joined in the aqueous phase solution of micro-capsule suspension, deionized water is supplied surplus, make the finely disseminated microcapsule suspension-suspending agent of present composition product, specifically in Table 8.
Table 8 embodiment 50,51 each component and weight portions
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR < 0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR > 1.5 is synergistic effect, on this basis, then carries out field trial.
Test method: after the effective inhibition concentration scope of each medicament is determined in prerun, medicament is established respectively 5 dosage by active constituent content and processed, and establishes clear water contrast.With reference to < < farm-chemical indoor determination test rule bactericide > >, carry out, adopt mycelial growth rate method to measure the virulence of medicament to crop germ.After 72h, by right-angled intersection method, measure colony diameter, calculate and respectively process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value to (x), with method of least squares, tries to achieve virulence regression equation (y=a+bx), and calculates thus the EC of every kind of medicament
50value.According to Wadley method, calculate the different proportioning synergy ratio (SR) of two medicaments, SR < 0.5 is antagonism simultaneously, and 0.5≤SR≤1.5 are summation action, and SR > 1.5 is synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and active component B shared ratio in combination;
A is fluorine mepanipyrim;
B is selected from a kind of in Carbatene, mancozeb, Propineb or zineb.
Virulence experiment part: test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Application Example two:
For trying disease: cucumber downy mildew;
Experimental scheme: effective inhibition concentration scope of determining the two different proportioning mixture of fluorine mepanipyrim and Carbatene through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to cucumber downy mildew of table 9 fluorine mepanipyrim and Carbatene
As shown in Table 9, the proportioning of the composite control cucumber downy mildew of fluorine mepanipyrim and Carbatene is when 1:80 ~ 60:1, synergy ratio SR is all greater than 1.5, illustrating that both are mixed within the scope of 1:80 ~ 60:1 all shows synergistic effect, the proportioning of fluorine mepanipyrim and Carbatene is in 1:30～10: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.90, when fluorine mepanipyrim and Carbatene weight ratio are 1:10, synergy ratio is maximum, and synergistic effect is the most obvious.Through applicant, test discovery, the proportioning of fluorine mepanipyrim and Carbatene is 1:30, 1:29, 1:28, 1:27, 1:26, 1:25, 1:24, 1:23, 1:22, 1:21, 1:20, 1:19, 1:18, 1:17, 1:16, 1:15, 1:14, 1:13, 1:12, 1:11, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1:4, 1:3, 1:2, 1:1, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, during 10:1 to shot hole, downy mildew, scab, spot defoliation, anthracnose, brown spot, black rot, blossom rot, ring spot, mildew is sick, rust, white rot, anthrachose of grape, Leucoplakia, spot blight, brown line is sick, black spot, balck shank, cotton disease, epidemic disease, soft rot, leaf spot, the control of stem wilt or damping off has obvious synergistic effect, synergy ratio is all more than 1.5.
Application Example three:
For trying disease: wheat powdery mildew;
Experimental scheme: effective inhibition concentration scope of determining the two different proportioning mixture of fluorine mepanipyrim and mancozeb through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to wheat powdery mildew of table 10 fluorine mepanipyrim and mancozeb
As shown in Table 10, the proportioning of the composite control wheat powdery mildew of fluorine mepanipyrim and mancozeb is when 1:80 ~ 60:1, synergy ratio SR is all greater than 1.5, illustrating that both are mixed within the scope of 1:80 ~ 60:1 all shows synergistic effect, the proportioning of fluorine mepanipyrim and mancozeb is in 1:35～5: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.90, when fluorine mepanipyrim and mancozeb weight ratio are 1:14, synergy ratio is maximum, and synergistic effect is the most obvious.Through applicant, test discovery, the proportioning of fluorine mepanipyrim and mancozeb is 5 ︰ 1, 4 ︰ 1, 3 ︰ 1, 2 ︰ 1, 1 ︰ 1, 1 ︰ 2, 1 ︰ 3, 1 ︰ 4, 1 ︰ 5, 1 ︰ 6, 1 ︰ 7, 1 ︰ 8, 1 ︰ 9, 1 ︰ 10, 1 ︰ 11, 1 ︰ 12, 1 ︰ 13, 1 ︰ 14, 1 ︰ 15, 1 ︰ 16, 1 ︰ 17, 1 ︰ 18, 1 ︰ 19, 1 ︰ 20, 1 ︰ 21, 1 ︰ 22, 1 ︰ 23, 1 ︰ 24, 1 ︰ 25, 1 ︰ 26, 1 ︰ 27, 1 ︰ 28, 1 ︰ 29, 1 ︰ 30, 1 ︰ 31, 1 ︰ 32, 1 ︰ 33, 1 ︰ 34, during 1 ︰ 35 to shot hole, downy mildew, scab, spot defoliation, anthracnose, brown spot, black rot, blossom rot, ring spot, mildew is sick, rust, white rot, anthrachose of grape, Leucoplakia, spot blight, brown line is sick, black spot, balck shank, cotton disease, epidemic disease, soft rot, leaf spot, the control of stem wilt or damping off has obvious synergistic effect, synergy ratio is all more than 1.5.
Application Example four:
For trying disease: downy mildew of garpe;
Experimental scheme: effective inhibition concentration scope of determining the two different proportioning mixture of fluorine mepanipyrim and Propineb through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to downy mildew of garpe of table 11 fluorine mepanipyrim and Propineb
As shown in Table 11, the composite proportioning of preventing and treating downy mildew of garpe of fluorine mepanipyrim and Propineb is when 1:80 ~ 60:1, synergy ratio SR is all greater than 1.5, illustrating that both are mixed within the scope of 1:80 ~ 60:1 all shows synergistic effect, the proportioning of fluorine mepanipyrim and Propineb is in 1:35～5: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.85, when fluorine mepanipyrim and Propineb weight ratio are 1:14, synergy ratio is maximum, and synergistic effect is the most obvious.Through applicant, test discovery, the proportioning of fluorine mepanipyrim and Propineb is 5 ︰ 1, 4 ︰ 1, 3 ︰ 1, 2 ︰ 1, 1 ︰ 1, 1 ︰ 2, 1 ︰ 3, 1 ︰ 4, 1 ︰ 5, 1 ︰ 6, 1 ︰ 7, 1 ︰ 8, 1 ︰ 9, 1 ︰ 10, 1 ︰ 11, 1 ︰ 12, 1 ︰ 13, 1 ︰ 14, 1 ︰ 15, 1 ︰ 16, 1 ︰ 17, 1 ︰ 18, 1 ︰ 19, 1 ︰ 20, 1 ︰ 21, 1 ︰ 22, 1 ︰ 23, 1 ︰ 24, 1 ︰ 25, 1 ︰ 26, 1 ︰ 27, 1 ︰ 28, 1 ︰ 29, 1 ︰ 30, 1 ︰ 31, 1 ︰ 32, 1 ︰ 33, 1 ︰ 34, during 1 ︰ 35 to shot hole, downy mildew, scab, spot defoliation, anthracnose, brown spot, black rot, blossom rot, ring spot, mildew is sick, rust, white rot, anthrachose of grape, Leucoplakia, spot blight, brown line is sick, black spot, balck shank, cotton disease, epidemic disease, soft rot, leaf spot, the control of stem wilt or damping off has obvious synergistic effect, synergy ratio is all more than 1.5.
Application Example five:
For trying disease: wheat rust;
Experimental scheme: effective inhibition concentration scope of determining the two different proportioning mixture of fluorine mepanipyrim and zineb through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to wheat rust of table 12 fluorine mepanipyrim and zineb
As shown in Table 12, the composite proportioning of preventing and treating wheat rust of fluorine mepanipyrim and zineb is when 1:80 ~ 60:1, synergy ratio SR is all greater than 1.5, illustrating that both are mixed within the scope of 1:80 ~ 60:1 all shows synergistic effect, the proportioning of fluorine mepanipyrim and zineb is in 1:35～5: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.85, when fluorine mepanipyrim and zineb weight ratio are 1:16, synergy ratio is maximum, and synergistic effect is the most obvious.Through applicant, test discovery, the proportioning of fluorine mepanipyrim and zineb is 5 ︰ 1, 4 ︰ 1, 3 ︰ 1, 2 ︰ 1, 1 ︰ 1, 1 ︰ 2, 1 ︰ 3, 1 ︰ 4, 1 ︰ 5, 1 ︰ 6, 1 ︰ 7, 1 ︰ 8, 1 ︰ 9, 1 ︰ 10, 1 ︰ 11, 1 ︰ 12, 1 ︰ 13, 1 ︰ 14, 1 ︰ 15, 1 ︰ 16, 1 ︰ 17, 1 ︰ 18, 1 ︰ 19, 1 ︰ 20, 1 ︰ 21, 1 ︰ 22, 1 ︰ 23, 1 ︰ 24, 1 ︰ 25, 1 ︰ 26, 1 ︰ 27, 1 ︰ 28, 1 ︰ 29, 1 ︰ 30, 1 ︰ 31, 1 ︰ 32, 1 ︰ 33, 1 ︰ 34, during 1 ︰ 35 to shot hole, downy mildew, scab, spot defoliation, anthracnose, brown spot, black rot, blossom rot, ring spot, mildew is sick, rust, white rot, anthrachose of grape, Leucoplakia, spot blight, brown line is sick, black spot, balck shank, cotton disease, epidemic disease, soft rot, leaf spot, the control of stem wilt or damping off has obvious synergistic effect, synergy ratio is all more than 1.5.
Effect experiment part: test medicine is researched and developed, provided by Shaanxi Mei Bang agricultural chemicals Co., Ltd, contrast medicament 10% fluorine mepanipyrim missible oil (autogamy), 70% Carbatene water dispersible granules (commercial), 80% mancozeb wettable powder (commercial), 70% Wettable propineb powder (commercial), 80% Zineb wettable powder (commercial).The investigation state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, dispenser is 1 time altogether.
Application Example hexafluoro mepanipyrim and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation cucumber downy mildew disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 30 days.Result of the test is as follows:
Table 13 fluorine mepanipyrim and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
As can be seen from Table 13, after fluorine mepanipyrim and active component B are composite, can effectively prevent and treat cucumber downy mildew, through applicant, test and find that fluorine mepanipyrim and active component B also can effectively prevent and treat powdery mildew of cucumber and cucumber anthracnose after composite, control efficiency is all higher than 96%, the preventive effect that is better than single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.Application Example seven fluorine mepanipyrims and active component B and the composite control tomato blight test of pesticide effectiveness thereof
This test arrangement is in Weinan City Pucheng County, Shaanxi Province, and investigation tomato blight disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 30 days.Result of the test is as follows:
Table 14 fluorine mepanipyrim and active component B and the composite control tomato blight test of pesticide effectiveness thereof
As can be seen from Table 14, after fluorine mepanipyrim and active component B are composite, can effectively prevent and treat tomato blight, through applicant, test and find that fluorine mepanipyrim and active component B also can effectively prevent and treat tomato powdery mildew, tomato downy mildew and anthracnose of tomato after composite, control efficiency is all higher than 95%, the preventive effect that is better than single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example octafluoro mepanipyrim and active component B and the composite wheat rust test of pesticide effectiveness of preventing and treating thereof
This test arrangement is in Weinan City Pucheng County, Shaanxi Province, and investigation wheat rust disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 30 days.Result of the test is as follows:
Table 15 fluorine mepanipyrim and active component B and the composite wheat rust test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 15, after fluorine mepanipyrim and active component B are composite, can effectively prevent and treat wheat rust, through applicant, test and find that fluorine mepanipyrim and active component B also can effectively prevent and treat wheat powdery mildew after composite, control efficiency is all higher than 95%, the preventive effect that is better than single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine fluorine mepanipyrims and active component B and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Weinan City Baishui County, and investigation alternaria leaf spot of apple disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 30 days.Result of the test is as follows:
Table 16 fluorine mepanipyrim and active component B and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
As can be seen from Table 16, after fluorine mepanipyrim and active component B are composite, can effectively prevent and treat alternaria leaf spot of apple, through applicant, test and find that fluorine mepanipyrim and active component B also can effectively prevent and treat apple marssonina leaf spot, black rot, scab, blossom rot, ring spot, mildew disease, anthracnose and rust after composite, control efficiency is all higher than 95%, the preventive effect that is better than single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten fluorine mepanipyrims and active component B and the composite control grape powdery mildew test of pesticide effectiveness thereof
This test arrangement is in Weinan City Pucheng County, Shaanxi Province, and investigation grape powdery mildew disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 30 days.Result of the test is as follows:
Table 17 fluorine mepanipyrim and active component B and the composite control grape powdery mildew test of pesticide effectiveness thereof
As can be seen from Table 17, after fluorine mepanipyrim and active component B are composite, can effectively prevent and treat grape powdery mildew, through applicant, test and find that fluorine mepanipyrim and active component B also can effectively prevent and treat fruit white rot of grape, anthracnose of grape and downy mildew of garpe after composite, control efficiency is all higher than 98%, the preventive effect that is better than single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 fluorine mepanipyrims and active component B and the composite citrus scab test of pesticide effectiveness of preventing and treating thereof
This test arrangement is at Shaanxi Province's Hanzhong City, and investigation citrus scab disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 30 days.Result of the test is as follows:
Table 18 fluorine mepanipyrim and active component B and the composite citrus scab test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 18, after fluorine mepanipyrim and active component B are composite, can effectively prevent and treat citrus scab, through applicant, test and find that fluorine mepanipyrim and active component B also can effectively prevent and treat citrus anthracnose after composite, control efficiency is all higher than 96%, the preventive effect that is better than single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After through different local throughout the country tests, draw, fluorine mepanipyrim and Carbatene, mancozeb, Propineb or zineb composite rear to the preventive effect of the Common Diseases such as the shot hole in various crop, downy mildew, scab, spot defoliation, anthracnose, brown spot, black rot, blossom rot, ring spot, mildew disease, rust, white rot, anthrachose of grape, Leucoplakia, spot blight, brown line disease, black spot, balck shank, cotton disease, epidemic disease, soft rot, leaf spot, stem wilt or damping off all more than 95%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. a bactericidal composition that contains fluorine mepanipyrim and thiocarbamates, effective active composition is active components A and active component B, it is characterized in that: active components A and active component B weight ratio are 1 ︰ 80 ~ 60 ︰ 1, described active components A is selected from fluorine mepanipyrim, and active component B is selected from a kind of in zineb, mancozeb, Propineb or zineb.
2. the bactericidal composition that contains fluorine mepanipyrim and thiocarbamates according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 60 ~ 40 ︰ 1.
3. the bactericidal composition that contains fluorine mepanipyrim and thiocarbamates according to claim 2, is characterized in that:
The weight ratio of fluorine mepanipyrim and Carbatene is 1 ︰ 30 ~ 10 ︰ 1;
The weight ratio of fluorine mepanipyrim and mancozeb, Propineb and zineb is 1 ︰ 35 ~ 5 ︰ 1.
4. according to the bactericidal composition that contains fluorine mepanipyrim and thiocarbamates described in any one in claims 1 to 3, it is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent or microcapsule suspension-suspending agent.
5. the bactericidal composition that contains fluorine mepanipyrim and thiocarbamates according to claim 4 is for preventing and treating the purposes of disease on crops.
6. purposes according to claim 5, is characterized in that: described disease comprises shot hole, downy mildew, scab, spot defoliation, anthracnose, brown spot, black rot, blossom rot, ring spot, mildew disease, rust, white rot, anthrachose of grape, Leucoplakia, spot blight, brown line disease, black spot, balck shank, cotton disease, epidemic disease, soft rot, leaf spot, stem wilt or damping off.
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