CN104412983A - Efficient bactericidal composition containing fluoride ether bacteria amide - Google Patents
Efficient bactericidal composition containing fluoride ether bacteria amide Download PDFInfo
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- CN104412983A CN104412983A CN201310400958.5A CN201310400958A CN104412983A CN 104412983 A CN104412983 A CN 104412983A CN 201310400958 A CN201310400958 A CN 201310400958A CN 104412983 A CN104412983 A CN 104412983A
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Abstract
The invention discloses an efficient bactericidal composition containing fluoride ether bacteria amide. The composition contains an active ingredient A and an active ingredient B, wherein the active ingredient A is fluoride ether bacteria amide, while the active ingredient B is selected from any one of cyazofamid, prochloraz or salt thereof, carbendazim, thiophanate-methyl, fenamidone and famoxadone; and the weight ratio of the active ingredient A to the active ingredient B is 1:80 to 60:1. The composition has a synergetic effect on multiple diseases harmful to agricultural production, the usage of pesticide is reduced, the residual amount of pesticide on crops is reduced, and environmental pollution is reduced. The composition is safe to human and livestock and good in environment compatibility, and drug resistance is unlikely to produce against diseases.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of efficient bactericidal composite on corps diseases of fluorine-containing ether bacterium acid amides.
Background technology
Fluorine ether bacterium acid amides (LH-2010A) the selectivity bactericide fluopicolide more similar than structure has wider fungicidal spectrum.The bacteriostatic activity of fluorine ether bacterium acid amides to cotton standing dead rhizoctonia and botrytis cinerea is the highest, to Phytophthora capsici and phytophthora infestans, there is higher antibacterial work, fluorine ether bacterium acid amides is obvious to cotton standing dead rhizoctonia bacteriostasis, its sclerotium significantly can be suppressed to produce and mycelium morphology factor, mycelia branch is increased, shortens, thicker; Fluorine ether bacterium acid amides has higher bacteriostatic activity to various plants pathogen, and obviously can suppress the multinomial physical signs of cotton standing dead rhizoctonia.
Cyazofamid, Prochloraz or its salt, carbendazim, thiophanate-methyl, Fenamidone Huo famoxadone all belong to common fungicide, are widely used in the disease of crops.
But in the real process of agricultural production, the problem that controlling disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of sterilization is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of synergy ratio.Study through inventor, find fluorine ether bacterium acid amides and cyazofamid, Prochloraz or its salt, carbendazim, thiophanate-methyl, Fenamidone Huo famoxadone is composite after can produce good synergistic effect, and not yet open about the relevant report that fluorine ether bacterium acid amides and cyazofamid, Prochloraz or its salt, carbendazim, thiophanate-methyl, Fenamidone Huo famoxadone are composite.
Summary of the invention
The object of the invention is to propose a kind of to there is synergistic function, the efficient bactericidal composite of use cost is low, preventive effect is good fluorine-containing ether bacterium acid amides.
The efficient bactericidal composite of the fluorine-containing ether bacterium acid amides that the present invention proposes contains active components A and active component B, activity is divided into A and active component B weight ratio is 1:80 ~ 60:1, described active components A is selected from fluorine ether bacterium acid amides, active component B is selected from the one in cyazofamid, Prochloraz or its salt, carbendazim, thiophanate-methyl, Fenamidone or famoxadone, and active components A and the preferred weight ratio of active component B are 1:60 ~ 40:1; The weight ratio being more preferably fluorine ether bacterium acid amides and cyazofamid is 1:30 ~ 30:1, the weight ratio of fluorine ether bacterium acid amides and Prochloraz or its salt is 1:25 ~ 20:1, the weight ratio of fluorine ether bacterium acid amides and carbendazim is 1:35 ~ 20:1, the weight ratio of fluorine ether bacterium acid amides and thiophanate-methyl is 1:30 ~ 20:1, the weight ratio of fluorine ether bacterium acid amides and Fenamidone is 1:30 ~ 30:1, and fluorine ether bacterium acid amides is Yu the weight ratio of famoxadone is 1:25 ~ 20:1; The weight ratio most preferably being fluorine ether bacterium acid amides and cyazofamid is 1:9 ~ 9:1, the weight ratio of fluorine ether bacterium acid amides and Prochloraz or its salt is 1:9 ~ 5:1, the weight ratio of fluorine ether bacterium acid amides and carbendazim is 1:14 ~ 4:1, the weight ratio of fluorine ether bacterium acid amides and thiophanate-methyl is 1:15 ~ 5:1, the weight ratio of fluorine ether bacterium acid amides and Fenamidone is 1:9 ~ 9:1, and fluorine ether bacterium acid amides is Yu the weight ratio of famoxadone is 1:9 ~ 4:1.
The efficient bactericidal composite of the fluorine-containing ether bacterium acid amides that the present invention proposes is for preventing and treating the purposes of disease on crops, and described crops comprise cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; Described disease comprises gray mold, phytophthora root rot, epidemic disease, powdery mildew, downy mildew, scab, anthracnose, peronospora tabacina, head blight, damping off, spot defoliation, rice blast, bakanae disease, brown spot, stalk break, leaf mold, leaf rot, banded sclerotial blight, shot hole or rust.
The weight ratio of active components A, active component B is 1:80 ~ 60:1.In usual composition, the weight percentage of active component is 0.5% ~ 90% of gross weight, is preferably 5% ~ 80%.According to different preparation types, active component content scope is different.Usually, liquid preparation contains the active substance of by weight 1% ~ 70%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 80%, is preferably 10% ~ 80%.
At least containing a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Bactericidal composition of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by common processing method known in those skilled in the art, after mixing with liquid flux or solid carrier by active substance, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer, disintegrant, antifreeze etc.
Bactericidal composition of the present invention, acceptable formulation in any sterilization can be processed on demand, wherein more preferably formulation is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent or microcapsule suspension-suspendinagent agent, can also make granule, seed coat agent, suspension seed-coating agent, ultra low volume liquids.
Composition comprises following constituent content when making wetting powder: active components A 0.5% ~ 60%, active component B0.5% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
Composition comprises following constituent content when making water dispersible granules: active components A 0.5% ~ 60%, active component B0.5% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following constituent content when making suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following constituent content when making suspension emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, solvent 1% ~ 15%, thickener 0 ~ 2%, emulsifier 2% ~ 12%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following constituent content when making aqueous emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 1% ~ 15%, antifreeze 0 ~ 8%, thickener 0 ~ 2%, defoamer 0.01% ~ 2%, deionized water supply surplus.
Composition comprises following constituent content when making microemulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 3% ~ 25%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water supply surplus.
Composition comprises following constituent content when making microcapsule suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, organic solvent 1% ~ 10%, emulsifier 1% ~ 7%, defoamer 0.01% ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Composition comprises following constituent content when making microcapsule suspension-suspendinagent agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, organic solvent 1% ~ 15%, emulsifier 1% ~ 6%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%;
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) fluorine ether bacterium acid amides and cyazofamid, Prochloraz or its salt, carbendazim, thiophanate-methyl, Fenamidone, famoxadone composite after, there is obvious synergy and lasting effect; (2) all greater activity is had to the disease on cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; (3) decrease pesticide usage amount, reduce the residual quantity of agricultural chemicals on crop, alleviate environmental pollution; (4) to person poultry safety, Environmental compatibility is good; And preparation adhesion strength strengthens, resistance of rainwater washing against.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Embodiment 1 ~ 16 wetting powder
Fluorine ether bacterium acid amides, active component B, dispersant, wetting agent, filler are mixed in mixed cylinder, mixes again after airslide disintegrating mill is pulverized, wetting powder product of the present invention can be obtained, specifically in table 1.
The each component of table 1 embodiment 1 ~ 16 and weight portion
Embodiment 17 ~ 32 water dispersible granules
Fluorine ether bacterium acid amides, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained together the particle diameter needed through air-flow crushing, then add other auxiliary agents such as binding agent (can add and can not add), obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, water dispersible granules product of the present invention can being obtained, specifically in table 2.
The each component of table 2 embodiment 17 ~ 32 and weight portion
By cyazofamid, Fenamidone, thiophanate-methyl, carbendazim, cyazofamid, Prochloraz or its salt interchange in table 1,2, novel formulation can be obtained.
Embodiment 33 ~ 48 suspending agent
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), mix through high speed shear, add fluorine ether bacterium acid amides, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water is supplied, and can obtain suspending agent product of the present invention, specifically in table 3.
The each component of table 3 embodiment 33 ~ 48 and weight portion
Embodiment 49 ~ 51 suspension emulsion
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add fluorine ether bacterium acid amides, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained fluorine ether bacterium amide suspending agents, then by active component B, solvent, emulsifier and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, surplus deionized water is supplied, obtained suspension emulsion product of the present invention, specifically in table 4.
The each component of table 4 embodiment 49 ~ 51 and weight portion
Embodiment 52 ~ 61 aqueous emulsion
Fluorine ether bacterium acid amides, active component B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, surplus deionized water is supplied; Aqueous emulsion product of the present invention can be obtained, specifically in table 5.
The each component of table 5 embodiment 52 ~ 61 and weight portion
Cyazofamid, Prochloraz, carbendazim, thiophanate-methyl, Fenamidone, famoxadone in table 3,5 are exchanged, can novel formulation be obtained.
Embodiment 62 ~ 64 microemulsion
Fluorine ether bacterium acid amides, active component B, solvent, emulsifier, antifreeze (can add and can not add), defoamer are fully mixed into the oil phase of homogeneous transparent, under agitation slowly add deionized water, form WO emulsion, again through agitating heating, make it rapid phase inversion and become oil-in-water type, be chilled to room temperature to make it to reach balance, after filtration, surplus deionized water is supplied; Microemulsion product of the present invention can be obtained, specifically in table 6.
The each component of table 6 embodiment 6264 and weight portion
Embodiment 65,66 microcapsule suspending agent
By fluorine ether bacterium acid amides, active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined in the aqueous phase solution containing emulsifier, pH adjusting agent, dispersant, surplus deionized water is supplied, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in table 7.
Table 7 real trip example 65,66 each component and weight portion
Embodiment 67,68 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition in the aqueous phase solution containing emulsifier, pH adjusting agent, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add fluorine ether bacterium acid amides, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent, then join in the aqueous phase solution of micro-capsule suspension by suspending agent, deionized water supplies surplus, make the finely disseminated microcapsule suspension-suspendinagent agent product of the present composition, specifically in table 8.
Table 8 embodiment 67,68 each component and weight portion
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First pass through Toxicity Determination, synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR<0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR>1.5 is synergistic effect, on this basis, then carry out field trial.
Test method: determine that after the effective inhibition concentration scope of each medicament, medicament establishes 5 dosage process respectively by active constituent content through prerun, if clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt mycelial growth rate method to measure medicament to the virulence of crop germ.Measure colony diameter by right-angled intersection method after 72h, calculate each process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), liquor strength (μ g/mL) converts logarithm value (x) to, try to achieve virulence regression equation (y=a+bx) with method of least squares, and calculate the EC of often kind of medicament thus
50value.Calculate two medicament different ratio synergies ratio (SR) according to Wadley method, SR<0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR>1.5 is synergistic effect simultaneously.Computing formula is as follows:
Wherein: a, b are respectively active components A and the ratio of active component B shared by combination;
A is fluorine ether bacterium acid amides;
B is selected from the one in cyazofamid, Prochloraz or its salt, carbendazim, thiophanate-methyl, Fenamidone, famoxadone.
Application Example two:
For examination disease: cucumber downy mildew
Test medicine provides by applicant.
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine ether bacterium acid amides and the former medicine of cyazofamid and the two different ratio mixture.
Toxicity test result
Table 9 fluorine ether bacterium acid amides and the composite toxicity test analysis of results table to cucumber downy mildew of cyazofamid
As shown in Table 9, fluorine ether bacterium acid amides and cyazofamid proportioning are all greater than 1.5 when 1:80 ~ 60:1 to the synergy ratio SR of cucumber downy mildew, both explanations mixture within the scope of 1:80 ~ 60:1 all shows synergistic effect, when the proportioning of fluorine ether bacterium acid amides and cyazofamid is at 1:30 ~ 30:1, synergistic effect is more outstanding, and synergy ratio is all more than 2.25; When the proportioning of fluorine ether bacterium acid amides and cyazofamid is at 1:9 ~ 9:1, synergistic effect is more outstanding, and synergy ratio is all more than 2.40.Testing through applicant the optimum ratio finding fluorine ether bacterium acid amides and cyazofamid is 30:1,20:1,15:1,10:1,6:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:10,1:13,1:15,1:20,1:25,1:30, especially when fluorine ether bacterium acid amides and cyazofamid weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example three
For examination disease: rice blast
Test medicine provides by applicant.
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine ether bacterium acid amides and the former medicine of Prochloraz and the two different ratio mixture.
Table 10 fluorine ether bacterium acid amides and the composite toxicity test analysis of results table to rice blast of Prochloraz
As shown in Table 10, fluorine ether bacterium acid amides and Prochloraz proportioning are all greater than 1.5 when 1:80 ~ 60:1 to the synergy ratio SR of rice blast, both explanations mixture within the scope of 1:80 ~ 60:1 all shows synergistic effect, when the proportioning of fluorine ether bacterium acid amides and Prochloraz is at 1:25 ~ 20:1, synergistic effect is more outstanding, and synergy ratio is all more than 2.25; When the proportioning of fluorine ether bacterium acid amides and Prochloraz is at 1:9 ~ 5:1, synergistic effect is more outstanding, and synergy ratio is all more than 2.40.Through applicant test find the optimum ratio of fluorine ether bacterium acid amides and Prochloraz be 20:1,15: 1,10: 1,6:1,5:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:13,1:15,1:20,1:25, especially when fluorine ether bacterium acid amides and Prochloraz weight ratio are 1:3, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example four
For examination disease: watermelon blight
Test medicine provides by applicant.
Experimental scheme: through preliminary experiment determination fluorine ether bacterium acid amides and the former medicine of salt of Prochloraz and effective inhibition concentration scope of the two different ratio mixture.
The composite toxicity test analysis of results table to watermelon blight of salt of table 11 fluorine ether bacterium acid amides and Prochloraz
As shown in Table 11, the salt proportioning of fluorine ether bacterium acid amides and Prochloraz is all greater than 1.5 when 1:80 ~ 60:1 to the synergy ratio SR of watermelon blight, both explanations mixture within the scope of 1:80 ~ 60:1 all shows synergistic effect, when the proportioning of the salt of fluorine ether bacterium acid amides and Prochloraz is at 1:25 ~ 20:1, synergistic effect is more outstanding, and synergy ratio is all more than 2.25; When the proportioning of the salt of fluorine ether bacterium acid amides and Prochloraz is at 1:9 ~ 5:1, synergistic effect is more outstanding, and synergy ratio is all more than 2.40.The optimum ratio testing the salt finding fluorine ether bacterium acid amides and Prochloraz through applicant is 20:1,15:1,10:1,6:1,5:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:13,1:15,1:20,1:25, especially when the salt weight ratio of fluorine ether bacterium acid amides and Prochloraz is 1:3, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example five
For examination disease: apple peels and cores
Test medicine provides by applicant.
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine ether bacterium acid amides and carbendazim active compound and the two different ratio mixture.
Table 12 fluorine ether bacterium acid amides and the composite toxicity test analysis of results table to apple peels and cores of carbendazim
As shown in Table 12, fluorine ether bacterium acid amides and carbendazim proportioning are all greater than 1.5 when 1:80 ~ 60:1 to the synergy ratio SR of apple peels and cores, both explanations mixture within the scope of l:80 ~ 60:1 all shows synergistic effect, when the proportioning of fluorine ether bacterium acid amides and carbendazim is at 1:35 ~ 20:1, synergistic effect is more outstanding, and synergy ratio is all more than 2.30.Especially when fluorine ether bacterium acid amides and carbendazim weight ratio are 1:7, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example six
For examination disease: flowers powdery mildew
Test medicine provides by applicant.
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine ether bacterium acid amides and thiophanate methyl raw pesticide and the two different ratio mixture.
Table 13 fluorine ether bacterium acid amides and the composite toxicity test analysis of results table to flowers powdery mildew of thiophanate-methyl
As shown in Table 13, fluorine ether bacterium acid amides and thiophanate-methyl proportioning are all greater than 1.5 when 1:80 ~ 60:1 to the synergy ratio SR of flowers powdery mildew, both explanations mixture within the scope of 1:80 ~ 60:1 all shows synergistic effect, when the proportioning of fluorine ether bacterium acid amides and thiophanate-methyl is at 1:30 ~ 20:1, synergistic effect is more outstanding, and synergy ratio is all more than 2.25.Especially when fluorine ether bacterium acid amides and thiophanate-methyl weight ratio are 1:4, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example seven
For examination disease: downy mildew of garpe
Test medicine provides by applicant.
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine ether bacterium acid amides and the former medicine of Fenamidone and the two different ratio mixture.
Table 14 fluorine ether bacterium acid amides and the composite toxicity test analysis of results table to downy mildew of garpe of Fenamidone
As shown in Table 14, fluorine ether bacterium acid amides and Fenamidone proportioning are all greater than 1.5 when 1:80 ~ 60:1 to the synergy ratio SR of downy mildew of garpe, both explanations mixture within the scope of 1:80 ~ 60:1 all shows synergistic effect, when the proportioning of fluorine ether bacterium acid amides and Fenamidone is at 1:30 ~ 30:1, synergistic effect is more outstanding, and synergy ratio is all more than 2.30.Especially when fluorine ether bacterium acid amides and Fenamidone weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example eight
For examination disease: powdery mildew of cucumber
Test medicine provides by applicant.
Experimental scheme: through preliminary experiment determination fluorine ether bacterium acid amides Yu effective inhibition concentration scope of the former medicine of famoxadone and the two different ratio mixture.
Table 15 fluorine ether bacterium acid amides is Yu the composite toxicity test analysis of results table to powdery mildew of cucumber of famoxadone
As shown in Table 15, fluorine ether bacterium acid amides and famoxadone proportioning are all greater than 1.5 when 1:80 ~ 60:1 to the synergy ratio SR of powdery mildew of cucumber, both explanations mixture within the scope of 1:80 ~ 60:1 all shows synergistic effect, when fluorine ether bacterium acid amides Yu when the proportioning of famoxadone is at 1:25 ~ 20:1, synergistic effect is more outstanding, and synergy ratio is all more than 2.25.Especially when fluorine ether bacterium acid amides and famoxadone weight ratio are 1:2, synergy ratio is maximum, and synergistic effect is the most obvious.
Through test find: fluorine ether bacterium acid amides and active component B composite after have obvious synergistic effect to the control of the gray mold in various crop, phytophthora root rot, epidemic disease, powdery mildew, downy mildew, scab, anthracnose, peronospora tabacina, head blight, damping off, spot defoliation, rice blast, bakanae disease, brown spot, stalk break, leaf mold, leaf rot, banded sclerotial blight, shot hole or rust, synergy ratio SR is all greater than 1.5.
Effect experiment part: test medicine by applicant research and develop, provide, contrast medicament 20% fluorine ether bacterium amide suspending agents (autogamy), 100 grams per liter cyazofamid suspending agents (commercial), 25% Prochloraz missible oil (commercial), 25% carbendazol wettable powder (commercial), 70% thiophanate-methyl wetting powder (commercial), 50% Fenamidone suspending agent (autogamy), 6.25% famoxadone wetting powder (autogamy).
Application Example nine fluorine ether bacterium acid amides and active component B and compositely prevent and treat the powdery mildew of cucumber test of pesticide effectiveness.
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation powdery mildew of cucumber disease index before medicine, in the dispenser of disease initial stage of origination, 3 days, 10 days, 20 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 16 fluorine ether bacterium acid amides and active component B and compositely prevent and treat the powdery mildew of cucumber test of pesticide effectiveness
As can be seen from Table 16, fluorine ether bacterium acid amides and active component B composite after effectively can prevent and treat powdery mildew of cucumber, through applicant test find fluorine ether bacterium acid amides and active component B composite after also can effectively prevent and treat cucumber downy mildew, epidemic disease, stalk break, scab, damping off, control efficiency is all higher than 96%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten fluorine ether bacterium acid amides and active component B and the composite control graw mold of tomato test of pesticide effectiveness thereof.
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation graw mold of tomato disease index before medicine, in the dispenser of disease initial stage of origination, 5 days, 15 days, 30 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 17 fluorine ether bacterium acid amides and active component B and the composite control graw mold of tomato test of pesticide effectiveness thereof
As can be seen from Table 17, fluorine ether bacterium acid amides and active component B composite after effectively can prevent and treat graw mold of tomato, through applicant test find fluorine ether bacterium acid amides and active component B composite after also can effectively prevent and treat cladosporium leaf and fruit mould of tomato, epidemic disease, leaf rot, control efficiency is all higher than 95%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten monofluoro-ether bacterium acid amides and Prochloraz or its salt and the composite control rice blast test of pesticide effectiveness thereof.
This test arrangement is in Hanzhong City suburb, Shaanxi Province, and investigation rice blast disease index before medicine, in the dispenser of disease initial stage of origination, 3 days, 7 days, 15 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 18 fluorine ether bacterium acid amides and Prochloraz or its salt and the composite control rice blast test of pesticide effectiveness thereof
As can be seen from Table 18, fluorine ether bacterium acid amides and Prochloraz or its salt and composite control rice blast thereof, through applicant test find fluorine ether bacterium acid amides and Prochloraz or its salt composite after also can effectively the water prevention rice sheath blight, bakanae disease, powdery mildew, banded sclerotial blight, control efficiency is all higher than 96%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten difluoro ether bacterium acid amides and active component B and the composite control apple peels and cores test of pesticide effectiveness thereof.
This test arrangement is at Shaanxi Province's Weinan City Baishui County, and investigation apple peels and cores disease index before medicine, in the dispenser of disease initial stage of origination, 3 days, 10 days, 20 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 19 fluorine ether bacterium acid amides and active component B and the composite control apple peels and cores test of pesticide effectiveness thereof
As can be seen from Table 19, fluorine ether bacterium acid amides and active component B composite after can effectively preventing and treating apple-tree spot defoliation, through applicant test find fluorine ether bacterium acid amides and active component B composite after also can effectively preventing and treating apple-tree powdery mildew, brown spot, scab, rust, control efficiency is all higher than 96%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten trifluoro bacterium acid amides and active component B and compositely prevent and treat the citrus scab test of pesticide effectiveness.
This test arrangement is in Hanzhong City suburb, Shaanxi Province, and investigation citrus scab disease index before medicine, in the dispenser of disease initial stage of origination, 10 days, 20 days, 30 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 20 fluorine ether bacterium acid amides and active component B and compositely prevent and treat the citrus scab test of pesticide effectiveness
As can be seen from Table 20, fluorine ether bacterium acid amides and active component B composite after effectively can prevent and treat citrus scab, through applicant test find fluorine ether bacterium acid amides and active component B composite after also can effectively prevent and treat citrus anthracnose, powdery mildew, control efficiency is all higher than 96%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten tetrafluoro ether bacterium acid amides and active component B and compositely prevent and treat the downy mildew of garpe test of pesticide effectiveness.
This test arrangement is in Weinan City Dali County, Shaanxi Province, and investigation downy mildew of garpe disease index before medicine, in the dispenser of disease initial stage of origination, 7 days, 14 days, 25 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 21 fluorine ether bacterium acid amides and active component B and compositely prevent and treat the downy mildew of garpe test of pesticide effectiveness
As can be seen from Table 21, fluorine ether bacterium acid amides and active component B composite after effectively can prevent and treat downy mildew of garpe, through applicant test find fluorine ether bacterium acid amides and active component B composite after also can effectively prevent and treat grape powdery mildew, anthracnose, control efficiency is all higher than 95%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, fluorine ether bacterium acid amides and the composite rear preventive effect to Common Diseases such as the gray mold in various crop, phytophthora root rot, epidemic disease, powdery mildew, downy mildew, scab, anthracnose, peronospora tabacina, head blight, damping off, spot defoliation, rice blast, bakanae disease, brown spot, stalk break, leaf mold, leaf rot, banded sclerotial blight, shot hole or rust of active component B are all more than 95%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. the efficient bactericidal composite of a fluorine-containing ether bacterium acid amides, effective active composition is active components A and active component B, it is characterized in that: active components A and active component B weight ratio are 1:80 ~ 60:1, described active components A is selected from fluorine ether bacterium acid amides, and active component B is selected from the one in cyazofamid, Prochloraz or its salt, carbendazim, thiophanate-methyl, Fenamidone or famoxadone; The salt of Prochloraz is selected from prochloraz-manganese chloride complex, prochloraz nantokite or prochloraz zinc salt.
2. the efficient bactericidal composite of fluorine-containing ether bacterium acid amides according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1:60 ~ 40:1.
3. the efficient bactericidal composite of fluorine-containing ether bacterium acid amides according to claim 2, is characterized in that:
The weight ratio of fluorine ether bacterium acid amides and cyazofamid is 1:30 ~ 30:1;
The weight ratio of fluorine ether bacterium acid amides and Prochloraz is 1:25 ~ 20:1;
The weight ratio of the salt of fluorine ether bacterium acid amides and Prochloraz is 1:25 ~ 20:1
The weight ratio of fluorine ether bacterium acid amides and carbendazim is 1:35 ~ 20:1;
The weight ratio of fluorine ether bacterium acid amides and thiophanate-methyl is 1:30 ~ 20:1;
The weight ratio of fluorine ether bacterium acid amides and Fenamidone is 1:30 ~ 30:1;
Fluorine ether bacterium acid amides is Yu the weight ratio of famoxadone is 1:25 ~ 20:1.
4. the efficient bactericidal composite of fluorine-containing ether bacterium acid amides according to any one of claim 1 to 3, is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent or microcapsule suspension-suspendinagent agent.
5. the efficient bactericidal composite of fluorine-containing ether bacterium acid amides according to claim 4 is for preventing and treating the purposes of disease on crops.
6. purposes according to claim 5, is characterized in that: described disease is gray mold, phytophthora root rot, epidemic disease, powdery mildew, downy mildew, scab, anthracnose, peronospora tabacina, head blight, damping off, spot defoliation, rice blast, bakanae disease, brown spot, stalk break, leaf mold, leaf rot, banded sclerotial blight, shot hole or rust.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105900999A (en) * | 2016-05-26 | 2016-08-31 | 南京华洲药业有限公司 | Sterilization composition containing fluoride ether bacteria amide and thiabendazole and application thereof |
| CN109566634A (en) * | 2017-09-28 | 2019-04-05 | 佛山市盈辉作物科学有限公司 | The synergistic composition of bacterium azoles is disliked containing fluorine ether bacterium amide and dichloro |
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| CN102754650A (en) * | 2012-07-24 | 2012-10-31 | 山东省联合农药工业有限公司 | Desflurane bacteria amide compound bactericide |
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| CN109566634A (en) * | 2017-09-28 | 2019-04-05 | 佛山市盈辉作物科学有限公司 | The synergistic composition of bacterium azoles is disliked containing fluorine ether bacterium amide and dichloro |
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