CN104412988A - Antibacterial composition containing fluoride ether bacteria amide and triazoles - Google Patents
Antibacterial composition containing fluoride ether bacteria amide and triazoles Download PDFInfo
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Abstract
The invention discloses a compound pesticide composition containing fluoride ether bacteria amide. The composition is prepared from the following effective ingredients: an active ingredient A and an active ingredient B, wherein the active ingredient A is fluoride ether bacteria amide, and the active ingredient B is any one selected from cymoxanil, propamocarb, propamocarb hydrochloride, fosetyl-aluminium, oxathiapiprolin, pyrimorph, activated ester and iprovalicarb; and the weight ratio of the active ingredient A to the active ingredient B is 1:80 to 60:1. The composition has a relatively high activity on multiple diseases of multiple crops, has a remarkable synergetic effect, and can be used for enlarging the bacteriocidal spectrum. The composition has the characteristics of small dosage, rain wash resistance and remarkable synergy.
Description
Technical field
The invention belongs to technical field of pesticide, relate to the application of bactericidal composition in crop pest of a kind of fluorine-containing ether bacterium acid amides and triazole type.
Technical background
Fluorine ether bacterium acid amides (LH-2010A) the selectivity bactericide fluopicolide more similar than structure has wider fungicidal spectrum.The bacteriostatic activity of fluorine ether bacterium acid amides to cotton standing dead rhizoctonia and botrytis cinerea is the highest, to Phytophthora capsici and phytophthora infestans, there is higher antibacterial work, fluorine ether bacterium acid amides is obvious to cotton standing dead rhizoctonia bacteriostasis, its sclerotium significantly can be suppressed to produce and mycelium morphology factor, mycelia branch is increased, shortens, thicker; Fluorine ether bacterium acid amides has higher bacteriostatic activity to various plants pathogen, and obviously can suppress the multinomial physical signs of cotton standing dead rhizoctonia.
In the real process of agricultural production, the problem that controlling disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of synergy ratio.Study through inventor, find by fluorine ether bacterium acid amides and Tebuconazole, own azoles alcohol, Difenoconazole, epoxiconazole, propiconazole, Flutriafol, nitrile bacterium azoles or Triadimenol mutually composite, there is good synergistic effect within the specific limits, and relevant composite about fluorine ether bacterium acid amides and Tebuconazole, own azoles alcohol, epoxiconazole, Flutriafol, propiconazole, phenyl ether methyl cyclic, nitrile bacterium azoles or Triadimenol, there is not yet relevant report at home and abroad at present.
Summary of the invention
The object of the invention is to propose a kind of to there is synergistic function, the bactericidal composition of use cost is low, preventive effect is good fluorine-containing ether bacterium acid amides and triazole type.
The present invention is achieved through the following technical solutions:
The bactericidal composition of a kind of fluorine-containing ether bacterium acid amides and triazole type, containing active components A and active component B, active components A and active component B weight ratio are 1:80 ~ 80:1, described active components A is selected from fluorine ether bacterium acid amides, and active component B is selected from the one in Tebuconazole, own azoles alcohol, Difenoconazole, epoxiconazole, propiconazole, Flutriafol, nitrile bacterium azoles or Triadimenol; The weight ratio being preferably active components A and active component B is 1:60 ~ 60:1; The weight ratio being more preferably fluorine ether bacterium acid amides and Tebuconazole is 1:20 ~ 20:1, the weight ratio of fluorine ether bacterium acid amides and own azoles alcohol is 1:20 ~ 20:1, the weight ratio of fluorine ether bacterium acid amides and Difenoconazole is 1:20 ~ 20:1, the weight ratio of fluorine ether bacterium acid amides and epoxiconazole is 1:20 ~ 20:1, the weight ratio of fluorine ether bacterium acid amides and propiconazole is 1:20 ~ 20:1, the weight ratio of fluorine ether bacterium acid amides and Flutriafol is 1:20 ~ 20:1, the weight ratio of fluorine ether bacterium acid amides and nitrile bacterium azoles is 1:20 ~ 20:1, and the weight ratio of fluorine ether bacterium acid amides and Triadimenol is 1:20 ~ 20:1; The weight ratio most preferably being fluorine ether bacterium acid amides and Tebuconazole is 1:9 ~ 9:1, the weight ratio of fluorine ether bacterium acid amides and own azoles alcohol is 1:9 ~ 9:1, the weight ratio of fluorine ether bacterium acid amides and Difenoconazole is 1:9 ~ 9:1, the weight ratio of fluorine ether bacterium acid amides and epoxiconazole is 1:9 ~ 9:1, the weight ratio of fluorine ether bacterium acid amides and propiconazole is 1:9 ~ 9:1, the weight ratio of fluorine ether bacterium acid amides and Flutriafol is 1:9 ~ 9:1, the weight ratio of fluorine ether bacterium acid amides and nitrile bacterium azoles is 1:9 ~ 9:1, and the weight ratio of fluorine ether bacterium acid amides and Triadimenol is 1:9 ~ 9:1.Bactericidal composition of the present invention, acceptable formulation in any sterilization can be processed on demand, wherein more preferably formulation is wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent, can also make seed coat agent, suspension seed-coating agent, granule, ultra low volume liquids.
Described fluorine-containing ether bacterium acid amides and the bactericidal composition of triazole type are for preventing and treating the disease of crop; Described crop is cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; Described disease is powdery mildew, leaf spot, net blotch, root rot, head blight, false smut, rice blast, bakanae disease, spot defoliation, black spot, anthrachose of grape, smut, scab, gray mold, stalk break, damping off, ring spot, banded sclerotial blight, stem wilt, full rot, anthracnose, rust, brown spot.
In bactericidal composition of the present invention, the content of active component depends on amount of application when being used alone, and also depends on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, simultaneously also relevant with target disease.In usual composition, the weight percentage of active component is 1% ~ 90% of gross weight, is preferably 5% ~ 80%.According to different preparation types, active component content scope is different.Liquids in general preparation contains the active substance of by weight 1% ~ 60%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 80%, is preferably 10% ~ 80%.
At least containing a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 2% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Bactericidal composition of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by processing method known in those skilled in the art, after mixing with liquid flux or solid carrier by active component, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, disintegrant, defoamer etc.According to different dosage form, can also containing antifreeze known in those skilled in the art etc. in preparation.
Composition comprises following component and content when making wetting powder: active components A 0.5% ~ 80%, active component B0.5% ~ 80%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, filler surplus.
Composition comprises following component and content when making water dispersible granules: active components A 0.5% ~ 80%, active component B0.5% ~ 80%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following component and content when making suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 1% ~ 10%, wetting agent 1% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component and content when making aqueous emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 20%, emulsifier 1% ~ 12%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making microemulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 10%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making suspension emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, emulsifier 1% ~ 10%, dispersant 1% ~ 10%, solvent 1% ~ 20%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component and content when making microcapsule suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 1% ~ 10%, dispersant 2% ~ 10%, solvent 1% ~ 10%, emulsifier 1% ~ 7%, pH adjusting agent 0.01% ~ 5%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making microcapsule suspension-suspendinagent agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 1% ~ 12%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, solvent 1% ~ 15%, emulsifier 1% ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) present composition has good synergy and lasting effect within the specific limits, and preventive effect is higher than single dose; (2) pesticide usage amount reduces, and reduces the residual quantity of agricultural chemicals on crop, alleviates environmental pollution; (3) fungicidal spectrum is expanded, to multiple diseases as powdery mildew, leaf spot, net blotch, root rot, head blight, false smut, rice blast, bakanae disease, spot defoliation, black spot, anthrachose of grape, smut, scab, gray mold, stalk break, damping off, ring spot, banded sclerotial blight, stem wilt, full rot, anthracnose, rust, brown spot etc. have greater activity.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Embodiment 1 ~ 14 wetting powder
By fluorine ether bacterium acid amides, active component B, dispersant, wetting agent, filler mixing, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, namely can be made into wetting powder product of the present invention.Specifically in table 1.
The each component of table 1 embodiment 1 ~ 14 and content
Embodiment 15 ~ 28 water dispersible granules
Fluorine ether bacterium acid amides, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained together the particle diameter needed through air-flow crushing, then add other auxiliary agents such as binding agent (can add and can not add), obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, water dispersible granules product of the present invention can being obtained, specifically in table 2.
The each component of table 2 embodiment 15 ~ 28 and content
Embodiment 29 ~ 42 suspending agent
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), mix through high speed shear, add fluorine ether bacterium acid amides, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water is supplied, and can obtain suspending agent product of the present invention, specifically in table 3.
The each component of table 3 embodiment 29 ~ 42 and content
Embodiment 43 ~ 50 aqueous emulsion
Fluorine ether bacterium acid amides, active component B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, obtained aqueous emulsion product of the present invention.Specifically in table 4.
The each component of table 4 embodiment 43 ~ 50 and content
Embodiment 51 ~ 58 microemulsion
Fluorine ether bacterium acid amides, active component B are dissolved in and are equipped with in the homogenizer of solvent, by emulsifier, antifreeze (can add and can not add), defoamer, join above-mentioned solution is housed homogenizer in, surplus deionized water gives strong mixing and homogenize after supplying, finally obtain the microemulsion product of the present invention that clear appearance is transparent.Specifically in table 5.
The each component of table 5 embodiment 51 ~ 58 and content
Tebuconazole, own azoles alcohol, Difenoconazole, epoxiconazole, propiconazole, Flutriafol, nitrile bacterium azoles or Triadimenol in table 1 ~ 5 are exchanged, can novel formulation be obtained.
Embodiment 59 ~ 61 suspension emulsion
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add fluorine ether bacterium acid amides, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained fluorine ether bacterium amide suspending agents, then by active component B, emulsifier, solvent and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, obtained suspension emulsion product of the present invention.Specifically in table 6.
The each component of table 6 embodiment 59 ~ 61 and content
Embodiment 62 ~ 64 microcapsule suspending agent
By fluorine ether bacterium acid amides, active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined in the aqueous phase solution containing emulsifier, pH adjusting agent, dispersant, defoamer, surplus deionized water is supplied, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in table 7.
The each component of table 7 embodiment 62 ~ 64 and content
Embodiment 65 ~ 67 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition in the aqueous phase solution containing emulsifier, pH adjusting agent, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add fluorine ether bacterium acid amides, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent, then join in the aqueous phase solution of micro-capsule suspension by suspending agent, deionized water supplies surplus, makes the finely disseminated microcapsule suspension-suspendinagent agent product of the present composition.Specifically in table 8.
The each component of table 8 embodiment 65 ~ 67 and content
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First pass through Toxicity Determination, synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR<0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR>1.5 is synergistic effect, on this basis, then carry out field trial.
Test method: determine that after the effective inhibition concentration scope of each medicament, medicament establishes 5 dosage process respectively by active constituent content through prerun, if clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt mycelial growth rate method to measure medicament to the virulence of crop germ.Measure colony diameter by right-angled intersection method after 72h, calculate each process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), liquor strength (μ g/mL) converts logarithm value (x) to, try to achieve virulence regression equation (y=a+bx) with method of least squares, and calculate the EC of often kind of medicament thus
50value.Calculate two medicament different ratio synergies ratio (SR) according to Wadley method, SR<0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR>1.5 is synergistic effect simultaneously.Computing formula is as follows:
Wherein: a, b are respectively active components A and the ratio of active component B shared by combination;
A is fluorine ether bacterium acid amides;
B is selected from the one in Tebuconazole, own azoles alcohol, Difenoconazole, epoxiconazole, propiconazole, Flutriafol, nitrile bacterium azoles or Triadimenol.
Application Example two:
For examination disease: sigatoka, test medicine provides by applicant, experimental scheme: through effective inhibition concentration scope of both preliminary experiment determination fluorine ether bacterium acid amides and Tebuconazole different ratio mixture.
Toxicity test result
Table 9 fluorine ether bacterium acid amides and the composite toxicity test analysis of results table to sigatoka of Tebuconazole
As shown in Table 9, fluorine ether bacterium acid amides and the composite proportioning of preventing and treating sigatoka of Tebuconazole are when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine ether bacterium acid amides and Tebuconazole is at 1:20 ~ 20:1, synergistic effect is more outstanding, synergy ratio is all more than 2.30, wherein obvious within the scope of 1:9 ~ 9:1, testing through applicant the proportioning finding fluorine ether bacterium acid amides and Tebuconazole is 1:20, 1:15, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1:4, 1:3, 1:2, 1:1, 3:2, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, 10:1, 15:1, 20:1, wherein fluorine ether bacterium acid amides is more maximum than synergy ratio when being 1:1 with tebuconazole weight, synergistic effect is the most obvious.
Application Example three:
For examination disease: rice sheath blight disease, test medicine provides by applicant, experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine ether bacterium acid amides and the former medicine of own azoles alcohol and the two different ratio mixture.
Toxicity test result
Table 10 fluorine ether bacterium acid amides and the composite toxicity test analysis of results table to rice sheath blight disease of own azoles alcohol
As shown in Table 10, the proportioning of fluorine ether bacterium acid amides and the composite water prevention rice sheath blight of own azoles alcohol is when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine ether bacterium acid amides and own azoles alcohol is at 1:20 ~ 20:1, synergistic effect is more outstanding, synergy ratio is all more than 2.30, wherein obvious within the scope of 1:9 ~ 9:1, testing through applicant the proportioning finding fluorine ether bacterium acid amides and own azoles alcohol is 1:20, 1:15, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1:4, 1:3, 1:2, 1:1, 3:2, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, 10:1, 15:1, 20:1, when wherein fluorine ether bacterium acid amides and own azoles alcohol weight ratio are 3:2, synergy ratio is maximum, synergistic effect is the most obvious.
Application Example four:
For examination disease: rice green smut, test medicine provides by applicant, experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine ether bacterium acid amides and epoxiconazole raw drug and the two different ratio mixture.
Toxicity test result
Table 11 fluorine ether bacterium acid amides and the composite toxicity test analysis of results table to rice green smut of epoxiconazole
As shown in Table 11, the proportioning of fluorine ether bacterium acid amides and the composite control rice green smut of epoxiconazole is when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine ether bacterium acid amides and epoxiconazole is at 1:20 ~ 20:1, synergistic effect is more outstanding, synergy ratio is all more than 2.25, wherein obvious within the scope of 1:9 ~ 9:1, testing through applicant the proportioning finding fluorine ether bacterium acid amides and epoxiconazole is 1:20, 1:15, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1:4, 1:3, 1:2, 1:1, 3:2, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, 10:1, 15:1, 20:1, when wherein fluorine ether bacterium acid amides and epoxiconazole weight ratio are 1:1, synergy ratio is maximum, synergistic effect is the most obvious.
Application Example five:
For examination disease: stripe rust of wheat, test medicine provides by applicant, experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine ether bacterium acid amides and the former medicine of Flutriafol and the two different ratio mixture.
Toxicity test result
Table 12 fluorine ether bacterium acid amides and the composite toxicity test analysis of results table to stripe rust of wheat of Flutriafol
As shown in Table 12, fluorine ether bacterium acid amides and the composite proportioning of preventing and treating stripe rust of wheat of Flutriafol are when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine ether bacterium acid amides and Flutriafol is at 1:20 ~ 20:1, synergistic effect is more outstanding, synergy ratio is all more than 2.25, wherein obvious within the scope of 1:9 ~ 9:1, testing through applicant the proportioning finding fluorine ether bacterium acid amides and Flutriafol is 1:20, 1:15, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1: 4, 1: 3, 1: 2, 1: 1, 3: 2, 2: 1, 3: 1, 4: 1, 5: 1, 6: 1, 7:1, 8:1, 9:1, 10:1, 15:1, 20:1, when wherein fluorine ether bacterium acid amides and Flutriafol weight ratio are 1:1, synergy ratio is maximum, synergistic effect is the most obvious.
Application Example six:
For examination disease: wheat powdery mildew, test medicine provides by applicant, experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine ether bacterium acid amides and propiconazole and the two different ratio mixture.
Toxicity test result
Table 13 fluorine ether bacterium acid amides and propiconazole compound are to the toxicity test analysis of results table of wheat powdery mildew
As shown in Table 13, fluorine ether bacterium acid amides and propiconazole compound prevent and treat the proportioning of wheat powdery mildew when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine ether bacterium acid amides and propiconazole is at 1:20 ~ 20:1, synergistic effect is more outstanding, synergy ratio is all more than 2.25, wherein obvious within the scope of 1:9 ~ 9:1, testing through applicant the proportioning finding fluorine ether bacterium acid amides and propiconazole is 20:1, 15:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:15, 1:20, when wherein fluorine ether bacterium acid amides and propiconazole weight ratio are 1:2, synergy ratio is maximum, synergistic effect is the most obvious.
Application Example seven:
For examination disease: pear scab, test medicine provides by applicant, experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine ether bacterium acid amides and difenoconazole technical material and the two different ratio mixture.
Toxicity test result
Table 14 fluorine ether bacterium acid amides and the composite toxicity test analysis of results table to pear scab of Difenoconazole
As shown in Table 14, the proportioning of fluorine ether bacterium acid amides and the composite control pear scab of Difenoconazole is when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine ether bacterium acid amides and Difenoconazole is at 1:20 ~ 20:1, synergistic effect is more outstanding, synergy ratio is all more than 2.30, wherein obvious within the scope of 1:9 ~ 9:1, testing through applicant the proportioning finding fluorine ether bacterium acid amides and Difenoconazole is 1:20, 1:15, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1:4, 1:3, 1:2, 1:1, 3:2, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, 10:1, 15:1, 20:1, when wherein fluorine ether bacterium acid amides and Difenoconazole weight ratio are 1:1, synergy ratio is maximum, synergistic effect is the most obvious.
Application Example eight:
For examination disease: powdery mildew of cucumber, test medicine provides by applicant, experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine ether bacterium acid amides and bulk myclobutanil and the two different ratio mixture.
Toxicity test result
Table 15 fluorine ether bacterium acid amides and myclobutanil compositional are to the toxicity test analysis of results table of powdery mildew of cucumber
As shown in Table 15, fluorine ether bacterium acid amides and myclobutanil compositional prevent and treat the proportioning of powdery mildew of cucumber when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine ether bacterium acid amides and nitrile bacterium azoles is at 1:20 ~ 20:1, synergistic effect is more outstanding, synergy ratio is all more than 2.25, wherein obvious within the scope of 1:9 ~ 9:1, testing through applicant the proportioning finding fluorine ether bacterium acid amides and nitrile bacterium azoles is 1:20, 1:15, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1:4, 1:3, 1:2, 1:1, 3:2, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, 10:1, 15:1, 20:1, when wherein fluorine ether bacterium acid amides and nitrile bacterium azoles weight ratio are 2:1, synergy ratio is maximum, synergistic effect is the most obvious.
Application Example nine:
For examination disease: grape grey mould, test medicine provides by applicant, experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine ether bacterium acid amides and the former medicine of Triadimenol and the two different ratio mixture.
Toxicity test result
Table 16 fluorine ether bacterium acid amides and the composite toxicity test analysis of results table to grape grey mould of Triadimenol
As shown in Table 16, the proportioning of fluorine ether bacterium acid amides and the composite control grape grey mould of Triadimenol is when 1:80 ~ 80:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 80:1 all shows synergistic effect, the proportioning of fluorine ether bacterium acid amides and Triadimenol is at 1:20 ~ 20:1, synergistic effect is more outstanding, synergy ratio is all more than 2.25, wherein obvious within the scope of 1:9 ~ 9:1, testing through applicant the proportioning finding fluorine ether bacterium acid amides and Triadimenol is 1:20, 1:15, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1:4, 1:3, 1:2, 1:1, 3:2, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, 10:1, 15:1, 20:1, when wherein fluorine ether bacterium acid amides and Triadimenol weight ratio are 2:3, synergy ratio is maximum, synergistic effect is the most obvious.
Through test find: fluorine ether bacterium acid amides and active component B composite after have obvious synergistic effect to the control of the powdery mildew in various crop, leaf spot, net blotch, root rot, head blight, false smut, rice blast, bakanae disease, spot defoliation, black spot, anthrachose of grape, smut, scab, gray mold, stalk break, damping off, ring spot, banded sclerotial blight, stem wilt, full rot, anthracnose, rust, brown spot, synergy ratio is all more than 1.5.
Effect experiment part: test medicine is researched and developed by applicant, provided, contrast medicament 10% fluorine ether bacterium amide suspending agents (autogamy), 6% tebuconazole microemulsion (commercial), 10% hexaconazole suspending agent (commercial), 12.5% epoxiconazole suspension concentrate (commercial), 12.5% Flutriafol suspending agent (commercial), 25% propiconazole emulsifiable concentrate (commercial), 10% micro-emulsion of phenyl ether methyl cyclic-azole (commercial), 12% nitrile bacterium azoles missible oil (commercial), 15% Triadimenol wetting powder (commercial).
Application Example ten fluorine ether bacterium acid amides and active component B and compositely prevent and treat the powdery mildew of cucumber test of pesticide effectiveness
This experimental establishment is in Xi'an City, Shanxi Province, and the investigation powdery mildew of cucumber state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 17 fluorine ether bacterium acid amides and active component B and compositely prevent and treat the powdery mildew of cucumber test of pesticide effectiveness
As can be seen from Table 17, fluorine ether bacterium acid amides and active component B and composite after effectively can prevent and treat powdery mildew of cucumber, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.Also have good preventive effect to scab of cucumber, drug effect is up to more than 96% simultaneously.
Application Example ten monofluoro-ether bacterium acid amides and active component B and the composite water prevention rice sheath blight test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, and the investigation rice sheath blight disease state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 3 days, 7 days, 15 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 18 fluorine ether bacterium acid amides and active component B and the composite water prevention rice sheath blight test of pesticide effectiveness thereof
As can be seen from Table 18, fluorine ether bacterium acid amides and active component B and composite after can the effective water prevention rice sheath blight, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long, has no adverse effects in test scope of medication to target crop.Also have good preventive effect to rice green smut, rice blast, bakanae disease, drug effect is up to more than 96% simultaneously.
Application Example ten difluoro ether bacterium acid amides and active component B and the composite control pear scab test of pesticide effectiveness thereof
This test arrangement is in Xianyang, Shanxi province city, and the investigation pear scab state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 19 fluorine ether bacterium acid amides and active component B and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 19, fluorine ether bacterium acid amides and active component B and composite rear efficiency thereof prevent and treat pear scab, and control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten trifluoro bacterium acid amides and active component B and compositely prevent and treat the sigatoka test of pesticide effectiveness
This test arrangement is in Nanning, and the investigation sigatoka state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 20 fluorine ether bacterium acid amides and active component B and compositely prevent and treat the sick test of pesticide effectiveness of sigatoka
As can be seen from Table 20, fluorine ether bacterium acid amides and active component B and composite after effectively can prevent and treat sigatoka, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.Also have good preventive effect to banana anthracnose, drug effect is up to more than 96% simultaneously.
Application Example ten tetrafluoro ether bacterium acid amides and active component B and the composite control grape grey mould test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Weinan City, and the investigation grape grey mould state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 21 fluorine ether bacterium acid amides and active component B and the composite control grape grey mould test of pesticide effectiveness thereof
As can be seen from Table 21, fluorine ether bacterium acid amides and active component B and composite after effectively can prevent and treat grape grey mould, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.Also have good preventive effect to grape powdery mildew, drug effect is up to more than 96% simultaneously.
Application Example 15 fluorine ether bacterium acid amides and active component B and the composite control wheat powdery mildew test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Weinan City, and the investigation wheat powdery mildew state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 22 fluorine ether bacterium acid amides and active component B and the composite control wheat powdery mildew test of pesticide effectiveness thereof
As can be seen from Table 22, fluorine ether bacterium acid amides and active component B and composite after effectively can prevent and treat wheat powdery mildew, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.Also have good preventive effect to wheat ring spot, rust, full rot, smut, drug effect is up to more than 96% simultaneously.
After draw through tests different local throughout the country, fluorine ether bacterium acid amides and Tebuconazole, own azoles alcohol, Difenoconazole, epoxiconazole, propiconazole, Flutriafol, nitrile bacterium azoles or Triadimenol composite rear to the powdery mildew in various crop, leaf spot, net blotch, root rot, head blight, false smut, rice blast, bakanae disease, spot defoliation, black spot, anthrachose of grape, smut, scab, gray mold, stalk break, damping off, ring spot, banded sclerotial blight, stem wilt, full rot, anthracnose, rust, the preventive effect of the Common Diseases such as brown spot is all more than 95%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. the compound pesticide composition of a fluorine-containing ether bacterium acid amides, effective active composition is active components A and active component B, it is characterized in that: the weight ratio of active components A and active component B is 1:80 ~ 60:1, described active components A is selected from fluorine ether bacterium acid amides, and active component B is selected from the one in white urea cyanogen, Propamocarb, propamocarb, phosethyl-Al, fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or iprovalicarb.
2. the compound pesticide composition of fluorine-containing ether bacterium acid amides according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1:60 ~ 40:1.
3. the compound pesticide composition of fluorine-containing ether bacterium acid amides according to claim 2, is characterized in that:
The weight ratio of fluorine ether bacterium acid amides and white urea cyanogen is 1:20 ~ 10:1;
The weight ratio of fluorine ether bacterium acid amides and Propamocarb is 1:30 ~ 30:1;
The weight ratio of fluorine ether bacterium acid amides and propamocarb is 1:30 ~ 10:1;
The weight ratio of fluorine ether bacterium acid amides and phosethyl-Al is 1:30 ~ 10:1;
The weight ratio of fluorine ether bacterium acid amides and fluorine thiazole pyrrole ethyl ketone is 1:20 ~ 10:1;
The weight ratio of fluorine ether bacterium acid amides and pyrimorph is 1:20 ~ 10:1;
The weight ratio of fluorine ether bacterium acid amides and Acibenzolar is 1:10 ~ 20:1;
The weight ratio of fluorine ether bacterium acid amides and iprovalicarb is 1:20 ~ 10:1.
4. the compound pesticide composition of the fluorine-containing ether bacterium acid amides according to any one of claims 1 to 3, is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent or microcapsule suspension-suspendinagent agent.
5. the compound pesticide composition of fluorine-containing ether bacterium acid amides according to claim 4 is for preventing and treating the purposes of crop pest.
6. purposes according to claim 5, is characterized in that: described disease is downy mildew, peronospora tabacina, epidemic disease, balck shank, damping off, banded sclerotial blight, rice blast, gray mold, powdery mildew, canker.
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Application publication date: 20150318 |