CN104399011A - Traditional Chinese medicine combination for treating esophageal cancer pain and preparation method thereof - Google Patents

Traditional Chinese medicine combination for treating esophageal cancer pain and preparation method thereof Download PDF

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CN104399011A
CN104399011A CN201410773403.XA CN201410773403A CN104399011A CN 104399011 A CN104399011 A CN 104399011A CN 201410773403 A CN201410773403 A CN 201410773403A CN 104399011 A CN104399011 A CN 104399011A
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rhizoma
pain
chinese medicine
radix
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孔馨苑
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Abstract

The invention discloses a traditional Chinese medicine combination for treating esophageal cancer pain. The traditional Chinese medicine combination is composed of the following ingredients in parts by weight: resina liquidamberis, turmeric yellow, edible tulip, pinellia ternata, poison nuts, corydalis tuber, betelnut, panax notoginseng, radix paeoniae rubra, fructus evodiae, coptis chinensis, chinaberry fruit, Chinese eaglewood, lignum dalbergiae odoriferae, frankincense, myrrh, szechuan lovage rhizome, radix curcumae, fritillary bulb, spina gleditsiae, borneol, nidus vespa and semen brassicae. The traditional Chinese medicine combination has the functions of invigorating blood circulation, relieving pain, regulating the flow of qi, dredging collaterals, dissipating stagnation and subsiding a swelling, and can effectively treat esophageal cancer pain.

Description

A kind of Chinese medicine composition for esophageal carcinoma pain and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for esophageal carcinoma pain.The invention still further relates to the preparation method of this Chinese medicine composition.
Background technology
The esophageal carcinoma is the malignant tumor occurring in epithelium of esophagus tissue, and China is esophageal carcinoma district occurred frequently, the generation of esophageal carcinoma and nitrous acid chronic stimulation, inflammation and wound, and inherited genetic factors and drinking-water, grain are relevant with the micronutrient levels in vegetable.Esophageal carcinoma is early stage, mid-term symptom choke with sobs sense at most to swallow, can die away and recur, and be everlasting patient's anxious state of mind time occur.More common with pain under xiphoid-process after breastbone.To have during ingest food after breastbone or pain under xiphoid-process, its character can in burning sample, acupuncture sample or tractive sample, to swallow coarse, scorching hot or irritant food for work.At the beginning in intermittent, when cancerous protuberance invade and neighbouring tissue or penetrate time, just can have violent and pain that is that continue.Painful area is normal not exclusively consistent with diseased region in esophagus.These pain symptoms make patient's dysphagia, be developed to liquid food also can not swallow by not swallowing food.And occur because patients diet's difficulty can cause malnutrition becoming thin, anemia, the sign such as dehydration or cachexia.Patient's body constitution declines, thus the cancer state of an illness also can increase the weight of, and forms vicious cycle.
Rich multiplex spasmolytic respite in current treatment. with pain under xiphoid-process after breastbone, but be also only the effect playing respite slight illness, and As time goes on, the using dosage of medicine also can increase gradually, not only bring great misery to sufferers themselves, and the family of patient also carries expensive medical fee.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition, it is obvious, cheap that this Chinese medicine composition has analgesic effect for treatment esophageal carcinoma pain, the feature that healing time is short.
Another object of the present invention is to provide the preparation method of the Chinese medicine preparation of this treatment esophageal carcinoma pain.
Inventor is in clinical treatment practice for many years, observe the misery that the esophageal carcinoma is brought to patient, according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out a kind of new formula of the Chinese medicine preparation for esophageal carcinoma pain repeatedly, the present invention selects Resina Liquidambaris, Rhizoma Curcumae Longae, Pseudobulbus Cremastrae Seu Pleiones, the Rhizoma Pinelliae, Semen Strychni, Rhizoma Corydalis, Semen Arecae, Radix Notoginseng, Radix Paeoniae Rubra, Fructus Evodiae, Rhizoma Coptidis, Fructus Toosendan, Lignum Aquilariae Resinatum, Lignum Dalbergiae Odoriferae, Olibanum, Myrrha, Rhizoma Chuanxiong, Radix Curcumae, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, Borneolum Syntheticum, Nidus Vespae, Semen Sinapis Albae combines, each efficacy of drugs is made by these drug regimens to produce synergism, make it that there is promoting blood circulation and stopping pain, regulating qi and dredging collateral, effect of mass dissipating and swelling eliminating, thus can effectively treat esophageal carcinoma pain.
The effect of Chinese medicine of the present invention:
Wherein:
Resina Liquidambaris: be the dry resin of Hamamelidaceae Plants Chinese sweet gum Liquidambar formosana Hance.Nature and flavor: pungent, micro-hardship are flat.Return lung, spleen channel.Effect: promoting blood circulation and stopping pain, removing toxic substances, granulation promoting, removing heat from blood.For injury from falling down, ulcer sore pain, spits blood, epistaxis, traumatic hemorrhage.
Rhizoma Curcumae Longae: be the dry rhizome of zingiberaceous plant Rhizoma Curcumae Longae Curcuma longa L..Nature and flavor: pungent, bitter, temperature.Return spleen, Liver Channel.Effect: removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia.Twinge for the breast side of body, amenorrhea , WEIJIA, rheumatism shoulder arm pain, tumbling and swelling.
Pseudobulbus Cremastrae Seu Pleiones: be the dry pseudobulb of orchid Cremastra appendiculata Cremastra appendiculata (D.Don) Makino, pleione bulbocodioides Pleione bulbocodioides (Franch.) Rolfe or Pleione yunnanensis Pleione yunnanensis Rolfe.Nature and flavor: sweet, pungent, cold, mild toxicity.Return liver, stomach, lung meridian.Effect: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.This product has the merit of detoxicating and resolving stagnation of pathogens detumescence, in recent years this product Guang general ground Yu mass in the abdomen mass in the abdomen and kinds of tumors.
The Rhizoma Pinelliae: be the tuber at the Rhizoma Arisaematis section plant Rhizoma Pinelliae (Pinellia ternata (Thunb.) Breit.).Nature and flavor are pungent, temperature, poisonous.Enter spleen, stomach warp.Effect: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass." property of medicine opinion ": expectorant saliva, appetite promoting and the spleen strengthening, anti-nausea, go expectorant in the heart full, lower lung qi, master coughs knot.
Semen Strychni: be the dry mature seed of loganiaceae plant Semen Strychni Strychnos nuxvomica L..Nature and flavor: bitter, temperature; Very toxic.Return liver, spleen channel.Effect: removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.For rheumatoid arthritis stubborn, paralysis and numbness, injury from falling down, ulcer sore pain; Poliomyelitis sequela, arthralgia.
Rhizoma Corydalis: be the dry tuber of papaveraceae plant corydalis Corydalis yanhusuo W. T. Wang.Nature and flavor: acrid, bitter, warm.Return liver, spleen channel.Effect: invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.The pungent loose temperature of this product is led to, the stagnation of QI in energy promoting the circulation of blood, stasis in gas, blood-activating and qi-promoting pain relieving, and the kind multiple pain controlled caused by stagnation of QI and blood, its analgesic effect is excellent.Record in " book on Chinese herbal medicine is looked for the truth ": Rhizoma Corydalis, no matter being blood is gas, amass and loose person, taking this power can be sensible, warm in nature with it, then can manage it in QI and blood can be smooth, and acrid in the mouth then can moisten can fall apart in QI and blood, so manage upper and lower all pains all over the body, merit of often walking alone is many.
Semen Arecae: be the dry mature seed of babassu Semen Arecae Areca catechu L..Nature and flavor: bitter, pungent, temperature.Return stomach, large intestine channel.Effect: killing insect and eliminating accumulation, sending down the abnormal ascending QI, row water, preventing the attack (or recurrence) of malaria.For cestode, ascarid, fasciolopsiasis buski, abdominal pain due to worm stagnation, stagnant dysentery, tenesmus, edema beriberi, malaria.Tang Materia Medica: main abdominal distention, raw end of smashing takes, diuretic paddy.Apply skin ulcer, the pain relieving of granulation promoting meat.Burn for ash, main tone psoriasis.
Radix Notoginseng: be the dry root of panax araliaceae plant Panax notoginseng (Burk.) F. H. Chen.Nature and flavor: sweet, micro-hardship, temperature.Return liver, stomach warp.Effect: dissipating blood stasis stops blooding, subduing swelling and relieving pain.For spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, and breast abdomen twinges, tumbling and swelling.Record in " book on Chinese herbal medicine is looked for the truth ": Radix Notoginseng, common people only know that function is stopped blooding bitterly, hardly realize bitterly because blood stasis then aches work, and blood is because only applying loose then blood.The bitter temperature of Radix Notoginseng abnormal smells from the patient, can in its blood stasis of blood systemization.
Radix Paeoniae Rubra: be the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall. or river Radix Paeoniae Rubra Paeonia veitchii Lynch.Nature and flavor are bitter, are slightly cold.Return Liver Channel.Effect: eliminating stasis to stop pain, clearing away heat and cooling blood, detumescence.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, injury from falling down, carbuncle skin infection.This product hardship is fallen, and has effect of promoting blood circulation to restore menstrual flow, loose Yu Xiao wei, row stagnation pain.
Fructus Evodiae: be rutaceae Fructus Evodiae Evodia rutaecarpa(Juss.) Benth., Shi Hu Evodia rutaecarpa(Juss.) the dry almost ripe fruit of Benth. var. officinalis (Dode) Huang or thin hair Fructus Evodiae Evodia rutaecarpa (Juss.) Benth. var. bodinieri (Dode) Huang.Nature and flavor: pungent, bitter, heat; Slightly poisonous.Return liver, spleen, stomach, kidney channel.Effect: dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.For headache due to JUE YIN disorder, colic of cold type is suffered from abdominal pain, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, abdominal distention, vomiting acid regurgitation, Diarrhoea, external treatment aphtha; Hypertension.
Rhizoma Coptidis: be the dry rhizome of ranunculaceae plant Rhizoma Coptidis Coptis chinensis Franch., Coptis deltoidea C.Y.Cheng et Hsiao Coptis deltoidea C. Y. Cheng et Hsiao or Coptis Teeta Wall Coptis teeta Wall..Nature and flavor: bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.Antibacterial action: staphylococcus aureus, Hemolytic streptococcus, streptococcus pneumoniae, meningococcus, dysentery bacterium, anthrax bacillus etc.Detoxication: antagonism bacteriotoxin, reduction staphylococcus aureus coagulase, hemolysin are tired, and reduce colibacillary virulence.Suppress kinds of experiments inflammation, effective ingredient is berberine, and Anti-inflammatory Mechanism discharges relevant with stimulation corticotropin.
Fructus Toosendan: be the dry mature fruit of Meliaceae plant Fructus Toosendan Melia toosendan Sieb. et Zucc..Nature and flavor: bitter, cold; Slightly poisonous.Return liver, small intestinal, urinary bladder channel.Effect: soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.
Lignum Aquilariae Resinatum: for Isolated From Thymelaeaceae Species Lignum Aquilariae Resinatum Aquilaria sinensis (Lour.) Gilg contains the timber of resin.Nature and flavor: pungent, bitter, tepor.Return spleen, stomach, kidney channel.Effect: promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting, helping inspiration to relieve asthma.
Lignum Dalbergiae Odoriferae: be the dry duramen of leguminous plant Lignum Dalbergiae Odoriferae wingceltis Dallbergia odarifera T.Chen trunk and root.Nature and flavor are pungent, temperature.Return liver, spleen channel.Effect: promoting flow of QI and blood, pain relieving, hemostasis.
Olibanum: the resin oozed out for Burseraceae Boswellia carterii platymiscium Boswellia carterii Boswellia carterii Birdw. [B. sacra Fluek.], medicine glue XIANGSHU B. bhawdajiana Birdw. and congener skin zone thereof.Nature and flavor: acrid, bitter, warm.GUIXIN, liver, spleen channel.Effect: promoting blood circulation and stopping pain, detumescence and promoting granulation.This product does not close up after being used for skin infection for a long time, and Chang Yuyu Myrrha compatibility, spreads on affected part outward.
Myrrha: the oleo-gum-resin of oozing out for Burseraceae bdellium plant myrrh Commiphora myrrha Engl. [C. molmol Engl.] and the trunk skin zone that belongs to his kind of plant together.Nature and flavor: bitter, flat.Enter Liver Channel.Effect: loose blood blood stasis removing, subduing swelling and relieving pain.Can be used for clinically treating chest pain.
Rhizoma Chuanxiong: be the dry rhizome of samphire Rhizoma Chuanxiong Ligusticum chuanxiong Hort..Nature and flavor: pungent, temperature.Return liver, gallbladder, heart channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.The pungent loose temperature of this product is led to, can top, up mountain peak, assigns the sea of blood, outer thorough fur, bypass extremity, can invigorate blood circulation and can circulation of qi promoting, and it is gas medicine in blood that former times people calls Rhizoma Chuanxiong, the functions such as pungent loose, the resolving depression of its residence of dangerous speech, sensible, pain relieving.
Radix Curcumae: be the dried root of zingiberaceous plant RADIX CURCUMAE Curcuma wenyujin Y. H. Chen et C. Ling, Rhizoma Curcumae Longae Curcuma longa L., Guangxi zedoary Curcuma kwangsiensis S. G. Lee et C. F. Liang or Rhizoma Curcumae Curcuma phaeocaulis Val..Nature and flavor: pungent, bitter, cold.Return liver, the heart, lung meridian.Effect: regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, removing heat from blood removing blood stasis with potent drugs.Cure mainly: all pains of breast abdomen side of body rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.The pungent loose hardship of this product is let out, heat clearing away cold in nature, can have one's ideas straightened out by heart fire-clearing upset-relieving.Radix Curcumae pungent drugs can disperse and bitter drugs can descend, fragrance a surname reach, cold in nature again can heat clearing away.Both entered edema caused by disorder of QI with promoting QI circulation for relieving depression, entered again blood system with cooling blood and dissolving stasis, and be the gas medicine in blood, be used for the treatment of the chest pain of QI and blood stasis.
Bulbus Fritillariae Thunbergii: be the dry bulb of liliaceous plant Bulbus Fritillariae Thunbergii Fritillaria thunbergii Miq..Nature and flavor: bitter, cold.Return lung, heart channel.Effect: heat clearing away eliminating stagnation, preventing phlegm from forming and stopping coughing.For wind-heat invading the lung, phlegm-fire cough, lung abscess, acute mastitis, scrofula, sore." book on Chinese herbal medicine just " is recorded: control greatly lung abscess lung and wither, cough with asthma, and spit blood, mental disorder, falls most in epistaxis, kind relieving stagnation, relieve the pain pain, kills parasites and treat sore throat, scrofula, acute mastitis carbuncle on the back, all carbuncle and ulcer toxic swellings, damp and hot malignant boil, anal fistula, incised wound is hemorrhage, burn pain, and than Bulbus Fritillariae Cirrhosae, the merit of falling clearly, not less than several times.
Spina Gleditsiae: be the dry Spina jujubae of leguminous plant Fructus Gleditsia Gleditsia sinensis Lam..Nature and flavor: pungent, temperature.Return lung, Liver Channel.Effect: detumescence and apocenosis, promoting blood circulation by removing wind.Tcm clinical practice is used for swollen ulcer drug all good therapeutic effect.Modern anticancer pharmacological research shows, Spina Gleditsiae has anticancer tumor-suppression activity.Modern pharmacology is studied its decoct flat board and to be burrowed method, has inhibitory action to staphylococcus aureus and micrococcus catarrhalis.
Borneolum Syntheticum: be the processed goods of Spore density Borneolum Syntheticum resin, or chemically synthesize for Camphora, Lignum Pini Nodi wet goods be processed into product.Nature and flavor: pungent, bitter, are slightly cold.GUIXIN, spleen, lung meridian.Effect: refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.Faint for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, and conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.This product has the effect of heat-clearing and toxic substances removing, erosion prevention and muscle growing, can control burn and scald.
Nidus Vespae: be Vespidae insecticide hornet or the nest belonging to nearly edge insecticide together.Nature and flavor: sweet are flat, poisonous.Gui Jing: liver; Stomach; Kidney channel.Effect: wind-expelling pain-stopping; The detumescence of rose poison; Killing parasites for relieving itching.Main air temperature arthralgia pain; Wind carious pain; Carbuncle malignant boil; Scrofula; Mouthpiece swells and ache; Anal fistula; Rubella pruritus; Skin stubborn dermatitis." detailed outline ": Nidus Vespae, positive bright medicine also.The person of surgery gear division and his sick use, also all gets its treating the poisonous disease with poisonous drugs, the merit ear of parasite killing of holding concurrently.
Semen Sinapis Albae: the dry mature seed of Cruciferae 1 year or biennial plant Caulis et Folium Sinapis albee SinapisalbaL..Nature and flavor: pungent, warm.Attach to the lung and stomach meridians.Effect: promoting the circulation of QI eliminating phlegm, warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain.Control phlegm retention cough with asthma, fullness and distention in the chest and hypochondrium pain, regurgitation is vomitted, aphasia due to apoplexy, and limbs arthralgia pain is numb, beriberi, carbuncle of yin nature, toxic swelling, treating swelling and pain by traumatic injury.Record in essentials of Matea Medica: Semen Sinapis Albae, a surname, promoting the circulation of QI eliminating phlegm.Xin Wen enters lung.Current meridians, warming middle-JIAO whets the appetite, diaphoresis cold expelling, promoting the circulation of QI eliminating phlegm, reducing swelling and alleviating pain.Expectorant is capable, swells and disappears, and the capable then pain of gas only.
Side's solution of the present invention is: Resina Liquidambaris promoting blood circulation and stopping pain in side, the circulation of qi promoting of Rhizoma Curcumae Longae removing blood stasis, inducing menstruation to relieve menalgia, Pseudobulbus Cremastrae Seu Pleiones, Rhizoma Pinelliae dissolving lump and resolving mass, Semen Strychni removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating, Rhizoma Corydalis regulating QI to relieve pain, above Six-element is monarch drug altogether, promoting blood circulation and stopping pain is carried out to affected area, regulating qi and dredging collateral, no matter being blood is gas, amass and loose person, pain endlessly, monarch drug fundamentally starting with from pain, the pain phenomenon of reduction of patient, the capable water removing food stagnancy of Semen Arecae, Radix Notoginseng subduing swelling and relieving pain, Radix Paeoniae Rubra eliminating stasis to stop pain, clearing away heat and cooling blood, Fructus Evodiae dispersing cold for relieving pain, Rhizoma Coptidis clearing away heat-fire, Fructus Toosendan soothing liver-QI promoting the circulation of QI to relieve pain, Lignum Aquilariae Resinatum, Lignum Dalbergiae Odoriferae promoting the circulation of QI to relieve pain, above eight tastes are ministerial drug altogether, increase monarch drug promoting blood circulation and stopping pain, effect of regulating qi and dredging collateral, alleviate slight illness during patients diet, the food-intake of the patient so also increased, promote the recovery of patient's body constitution.Olibanum, Myrrha fall apart blood blood stasis removing, subduing swelling and relieving pain, Rhizoma Chuanxiong blood-activating and qi-promoting, Radix Curcumae regulating qi to disperse stagnation, Bulbus Fritillariae Thunbergii heat clearing away eliminating stagnation, Spina Gleditsiae detumescence and apocenosis, Borneolum Syntheticum clearing away heat to alleviate pain, Nidus Vespae wind-expelling pain-stopping, Semen Sinapis Albae warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain, above a few taste is adjuvant drug altogether, increase curative effect of medication, reduction of patient is ailing.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, has effect of promoting blood circulation and stopping pain, regulating qi and dredging collateral, mass dissipating and swelling eliminating, can effectively treat esophageal carcinoma pain.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Resina Liquidambaris 1-5 part, Rhizoma Curcumae Longae 13-23 part, Pseudobulbus Cremastrae Seu Pleiones 15-25 part, Rhizoma Pinelliae 7-17 part, Semen Strychni 4-14 part, Rhizoma Corydalis 25-35 part, Semen Arecae 10-20 part, Radix Notoginseng 3-9 part, Radix Paeoniae Rubra 7-17 part, Fructus Evodiae 4-14 part, Rhizoma Coptidis 4-14 part, Fructus Toosendan 7-17 part, Lignum Aquilariae Resinatum 1-5 part, Lignum Dalbergiae Odoriferae 3-9 part, Olibanum 4-14 part, Myrrha 4-14 part, Rhizoma Chuanxiong 10-20 part, Radix Curcumae 10-20 part, Bulbus Fritillariae Thunbergii 10-20 part, Spina Gleditsiae 13-23 part, Borneolum Syntheticum 1-3 part, Nidus Vespae 7-17 part, Semen Sinapis Albae 4-14 part.
Wherein be preferably: Resina Liquidambaris 3 parts, 18 parts, Rhizoma Curcumae Longae, Pseudobulbus Cremastrae Seu Pleiones 20 parts, the Rhizoma Pinelliae 12 parts, Semen Strychni 9 parts, Rhizoma Corydalis 30 parts, Semen Arecae 15 parts, Radix Notoginseng 6 parts, Radix Paeoniae Rubra 12 parts, Fructus Evodiae 9 parts, Rhizoma Coptidis 9 parts, Fructus Toosendan 12 parts, Lignum Aquilariae Resinatum 3 parts, Lignum Dalbergiae Odoriferae 6 parts, Olibanum 9 parts, Myrrha 9 parts, Rhizoma Chuanxiong 15 parts, Radix Curcumae 15 parts, Bulbus Fritillariae Thunbergii 15 parts, Spina Gleditsiae 18 parts, Borneolum Syntheticum 2 parts, Nidus Vespae 12 parts, Semen Sinapis Albae 9 parts.
A kind of preparation method of the Chinese medicine preparation for esophageal carcinoma pain is as follows:
Step one: according to weight proportion of the present invention, becomes medicated bag by Semen Strychni, Semen Arecae, Fructus Evodiae, Fructus Toosendan, Semen Sinapis Albae bundle, is put in water and soaks about 45 minutes, filters, for subsequent use;
Step 2: by weight proportion of the present invention, takes Resina Liquidambaris, Olibanum, Myrrha, Borneolum Syntheticum powder breakdown mill to 120 mesh sieve, for subsequent use;
Step 3: by weight proportion of the present invention, takes Rhizoma Curcumae Longae, Radix Notoginseng, Radix Paeoniae Rubra, Rhizoma Coptidis, Lignum Aquilariae Resinatum, Lignum Dalbergiae Odoriferae, Rhizoma Chuanxiong, Radix Curcumae puts into marmite and add after step one is soaked and remain cold water, exceed powder 3 ~ 4 li centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 3 cm is added in residue medicinal residues, add medicated bag in Pseudobulbus Cremastrae Seu Pleiones, the Rhizoma Pinelliae, Rhizoma Corydalis, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, Nidus Vespae and step one, decoct 30 minutes, filter, waste, for subsequent use;
Step 4: twice filtrate in step 3 is merged, adds the powder in step 2 while hot, stir, both the external-use lotion for the treatment of esophageal carcinoma pain of the present invention.
This pharmaceutical preparation using method is: the medicinal liquid be fried open can fumigate affected part while hot, cleans when water temperature is suitable, about 20 minutes.
Medicine of the present invention has the effects such as promoting blood circulation and stopping pain, regulating qi and dredging collateral, mass dissipating and swelling eliminating, and analgesic effect is obvious, cheap, healing time is short, according to clinical 150 routine patient view statistics, use specific embodiment of the invention medicine one the total effective rate course for the treatment of 80%, two the total effective rate course for the treatment of 92%.
Detailed description of the invention
Embodiment one, Resina Liquidambaris 1 part, 13 parts, Rhizoma Curcumae Longae, Pseudobulbus Cremastrae Seu Pleiones 15 parts, the Rhizoma Pinelliae 7 parts, Semen Strychni 4 parts, Rhizoma Corydalis 25 parts, Semen Arecae 10 parts, Radix Notoginseng 3 parts, Radix Paeoniae Rubra 7 parts, Fructus Evodiae 4 parts, Rhizoma Coptidis 4 parts, Fructus Toosendan 7 parts, Lignum Aquilariae Resinatum 1 part, Lignum Dalbergiae Odoriferae 3 parts, Olibanum 4 parts, Myrrha 4 parts, Rhizoma Chuanxiong 10 parts, Radix Curcumae 10 parts, Bulbus Fritillariae Thunbergii 10 parts, Spina Gleditsiae 13 parts, Borneolum Syntheticum 1 part, Nidus Vespae 7 parts, Semen Sinapis Albae 4 parts.
Embodiment two, Resina Liquidambaris 3 parts, 18 parts, Rhizoma Curcumae Longae, Pseudobulbus Cremastrae Seu Pleiones 20 parts, the Rhizoma Pinelliae 12 parts, Semen Strychni 9 parts, Rhizoma Corydalis 30 parts, Semen Arecae 15 parts, Radix Notoginseng 6 parts, Radix Paeoniae Rubra 12 parts, Fructus Evodiae 9 parts, Rhizoma Coptidis 9 parts, Fructus Toosendan 12 parts, Lignum Aquilariae Resinatum 3 parts, Lignum Dalbergiae Odoriferae 6 parts, Olibanum 9 parts, Myrrha 9 parts, Rhizoma Chuanxiong 15 parts, Radix Curcumae 15 parts, Bulbus Fritillariae Thunbergii 15 parts, Spina Gleditsiae 18 parts, Borneolum Syntheticum 2 parts, Nidus Vespae 12 parts, Semen Sinapis Albae 9 parts.
Embodiment three, Resina Liquidambaris 5 parts, 23 parts, Rhizoma Curcumae Longae, Pseudobulbus Cremastrae Seu Pleiones 25 parts, the Rhizoma Pinelliae 17 parts, Semen Strychni 14 parts, Rhizoma Corydalis 35 parts, Semen Arecae 20 parts, Radix Notoginseng 9 parts, Radix Paeoniae Rubra 17 parts, Fructus Evodiae 14 parts, Rhizoma Coptidis 14 parts, Fructus Toosendan 17 parts, Lignum Aquilariae Resinatum 5 parts, Lignum Dalbergiae Odoriferae 9 parts, Olibanum 14 parts, Myrrha 14 parts, Rhizoma Chuanxiong 20 parts, Radix Curcumae 20 parts, Bulbus Fritillariae Thunbergii 20 parts, Spina Gleditsiae 23 parts, Borneolum Syntheticum 3 parts, Nidus Vespae 17 parts, Semen Sinapis Albae 14 parts.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Treatment patient 150 example, wherein male 90 example, women 60 example, M-F 1.5:1,48 years old mean age, the course of disease is not etc.
Two, Therapeutic Method
According to Medications Example two of the present invention, and the external-use lotion that preferred preparation method is made, the medicinal liquid be fried open can fumigate affected part while hot, cleans when water temperature is suitable, about 20 minutes.Every day 2 times 7 days is a course for the treatment of.
Three, efficacy assessment standard
1, cure: the pain phenomenon that esophageal carcinoma causes disappears, and Nutritional condition of body takes a turn for the better to some extent.
2, take a turn for the better: the pain phenomenon that esophageal carcinoma causes is eased, and Nutritional condition of body takes a turn for the better gradually.
3, do not heal: the pain that esophageal carcinoma causes is without any improvement.
Four, therapeutic outcome statistics
Wherein: total effective rate=cure rate+improvement rate
Shown by the statistics of therapeutic outcome, Chinese medicine of the present invention has good clinical effectiveness in treatment esophageal carcinoma pain, effectively can improve the cure rate for the treatment of, be worth promoting in clinical practice.
Model case and curative effect:
Case one, Wu, man, 41 years old, because of diet then choke, especially with drinking-water for very, Mental fatigue, chest pain, go examination in hospital to be diagnosed as esophageal carcinoma, patient is because of chest pain dysphagia, and hospital adopts various measures, and effect is all not obvious, rear employing case method of the present invention, washout affected part, after using two courses for the treatment of, esophageal carcinoma pain disappears gradually, two courses for the treatment of of rear continuation use, health nutritional status also recovers to some extent, and pain disappears.
Case two, Zhang, man, 50 years old, chest pain when patient has a swallowing act, and prolong with sputum crudum, hoarseness, be diagnosed as esophageal carcinoma, patient is difficult to stand because of the pain that esophageal carcinoma causes, and adopts the mode of multiple pain relieving, effect is all undesirable, rear employing case method of the present invention, washout affected part, after using a course for the treatment of, esophageal carcinoma pain disappears gradually, two courses for the treatment of of rear continuation use, health nutritional status also recovers to some extent, and pain disappears.

Claims (4)

1. the Chinese medicine composition for esophageal carcinoma pain, it is characterized in that, this Chinese medicine composition is made up of the medicine of following weight portion: Resina Liquidambaris 1-5 part, Rhizoma Curcumae Longae 13-23 part, Pseudobulbus Cremastrae Seu Pleiones 15-25 part, Rhizoma Pinelliae 7-17 part, Semen Strychni 4-14 part, Rhizoma Corydalis 25-35 part, Semen Arecae 10-20 part, Radix Notoginseng 3-9 part, Radix Paeoniae Rubra 7-17 part, Fructus Evodiae 4-14 part, Rhizoma Coptidis 4-14 part, Fructus Toosendan 7-17 part, Lignum Aquilariae Resinatum 1-5 part, Lignum Dalbergiae Odoriferae 3-9 part, Olibanum 4-14 part, Myrrha 4-14 part, Rhizoma Chuanxiong 10-20 part, Radix Curcumae 10-20 part, Bulbus Fritillariae Thunbergii 10-20 part, Spina Gleditsiae 13-23 part, Borneolum Syntheticum 1-3 part, Nidus Vespae 7-17 part, Semen Sinapis Albae 4-14 part.
2. the Chinese medicine composition for esophageal carcinoma pain according to claims 1, it is characterized in that, be made up of the medicine of following weight portion: Resina Liquidambaris 3 parts, 18 parts, Rhizoma Curcumae Longae, Pseudobulbus Cremastrae Seu Pleiones 20 parts, the Rhizoma Pinelliae 12 parts, Semen Strychni 9 parts, Rhizoma Corydalis 30 parts, Semen Arecae 15 parts, Radix Notoginseng 6 parts, Radix Paeoniae Rubra 12 parts, Fructus Evodiae 9 parts, Rhizoma Coptidis 9 parts, Fructus Toosendan 12 parts, Lignum Aquilariae Resinatum 3 parts, Lignum Dalbergiae Odoriferae 6 parts, Olibanum 9 parts, Myrrha 9 parts, Rhizoma Chuanxiong 15 parts, Radix Curcumae 15 parts, Bulbus Fritillariae Thunbergii 15 parts, Spina Gleditsiae 18 parts, Borneolum Syntheticum 2 parts, Nidus Vespae 12 parts, Semen Sinapis Albae 9 parts.
3. the Chinese medicine preparation for esophageal carcinoma pain according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is external-use lotion.
4. for a preparation method for the Chinese medicine preparation of esophageal carcinoma pain, it is characterized in that, preparation method is as follows: step one: according to weight proportion of the present invention, Semen Strychni, Semen Arecae, Fructus Evodiae, Fructus Toosendan, Semen Sinapis Albae bundle are become medicated bag, be put in water and soak about 45 minutes, filter, for subsequent use; Step 2: by weight proportion of the present invention, takes Resina Liquidambaris, Olibanum, Myrrha, Borneolum Syntheticum powder breakdown mill to 120 mesh sieve, for subsequent use; Step 3: by weight proportion of the present invention, takes Rhizoma Curcumae Longae, Radix Notoginseng, Radix Paeoniae Rubra, Rhizoma Coptidis, Lignum Aquilariae Resinatum, Lignum Dalbergiae Odoriferae, Rhizoma Chuanxiong, Radix Curcumae puts into marmite and add after step one is soaked and remain cold water, exceed powder 3 ~ 4 li centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 3 cm is added in residue medicinal residues, add medicated bag in Pseudobulbus Cremastrae Seu Pleiones, the Rhizoma Pinelliae, Rhizoma Corydalis, Bulbus Fritillariae Thunbergii, Spina Gleditsiae, Nidus Vespae and step one, decoct 30 minutes, filter, waste, for subsequent use; Step 4: twice filtrate in step 3 is merged, adds the powder in step 2 while hot, stir, both the external-use lotion for the treatment of esophageal carcinoma pain of the present invention.
CN201410773403.XA 2014-12-16 2014-12-16 Traditional Chinese medicine combination for treating esophageal cancer pain and preparation method thereof Pending CN104399011A (en)

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CN111991510A (en) * 2020-10-09 2020-11-27 吴江南 Blood stasis removing, collateral dredging and antibacterial liquid and preparation method thereof
CN116159117A (en) * 2023-02-22 2023-05-26 张莹雯 Traditional Chinese medicine composition for treating cancer pain and malignant pleuroperitoneal cavity effusion and preparation method thereof

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