CN111991510A - Blood stasis removing, collateral dredging and antibacterial liquid and preparation method thereof - Google Patents

Blood stasis removing, collateral dredging and antibacterial liquid and preparation method thereof Download PDF

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CN111991510A
CN111991510A CN202011072723.4A CN202011072723A CN111991510A CN 111991510 A CN111991510 A CN 111991510A CN 202011072723 A CN202011072723 A CN 202011072723A CN 111991510 A CN111991510 A CN 111991510A
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parts
borax
dredging
collateral
dried alum
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吴江南
邓雅萍
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Abstract

The invention discloses a blood stasis removing and collateral dredging antibacterial liquid and a preparation method thereof, belonging to the field of traditional Chinese medicines, wherein the antibacterial liquid is prepared from edible tulip, myrrh, ligusticum wallichii, arisaema cum bile, venenum bufonis, rhizoma paridis, frankincense, dried alum, borax, radix ampelopsis, pseudo-ginseng, radix balanophorae, borneol and honeycomb.

Description

Blood stasis removing, collateral dredging and antibacterial liquid and preparation method thereof
Technical Field
The invention relates to the field of traditional Chinese medicines, and in particular relates to a stasis-removing collateral-dredging antibacterial liquid and a preparation method thereof.
Background
Cancer disease, one of the absolute symptoms, seriously harms people's health. Thus, no effective therapeutic method for radically treating cancer has been developed so far. The pain of cancer diseases brought to bodies is huge, the existing pain-relieving medicine for oral administration can cause no small wound to patients, the traditional Chinese medicine method for oral administration is adopted to relieve pain of the patients, but the pain-relieving effect is difficult to achieve because the patients have difficulty in taking the medicine or vomit after taking the medicine. The painful skin surface is easy to be infected with bacteria, and the like, and on the premise of ensuring that the painful part can remove blood stasis, dredge collaterals, relieve swelling and relieve pain, the skin can be disinfected and inhibited from bacteria, so that the skin is clean and sanitary. Therefore, the invention provides a stasis removing and collateral dredging antibacterial liquid and a preparation method thereof, and aims to overcome the defects in the prior art.
Disclosure of Invention
Aiming at the problems, the invention provides a bacteriostatic solution for removing blood stasis and dredging collaterals and a preparation method thereof.
In order to achieve the above object, the present invention adopts the following technical solutions:
the blood stasis removing, collateral dredging and bacteriostasis liquid is characterized by being prepared from the following raw materials in parts by weight: 3-15 parts of edible tulip, 2-14 parts of myrrh, 6-20 parts of ligusticum wallichii, 3-18 parts of arisaema, 2-9 parts of venenum bufonis, 2-11 parts of rhizoma paridis, 3-9 parts of frankincense, 3-13 parts of dried alum, 4-17 parts of borax, 4-16 parts of radix ampelopsis, 2-13 parts of pseudo-ginseng, 6-19 parts of balanophora glauca, 3-13 parts of borneol and 3-15 parts of honeycomb.
Preferably, the feed additive is prepared from the following raw materials in parts by weight: 5-10 parts of edible tulip, 5-10 parts of myrrh, 10-15 parts of ligusticum wallichii, 6-15 parts of arisaema consanguineum, 3-7 parts of venenum bufonis, 4-8 parts of rhizoma paridis, 4-7 parts of frankincense, 5-10 parts of dried alum, 8-13 parts of borax, 7-12 parts of radix ampelopsis, 5-10 parts of pseudo-ginseng, 10-15 parts of balanophora glauca, 5-10 parts of borneol and 5-10 parts of honeycomb.
Preferably, the feed additive is prepared from the following raw materials in parts by weight: 8 parts of edible tulip, 8 parts of myrrh, 12 parts of szechuan lovage rhizome, 11 parts of arisaema, 5 parts of venenum bufonis, 5 parts of rhizoma paridis, 5 parts of frankincense, 7 parts of dried alum, 10 parts of borax, 10 parts of radix ampelopsis, 7 parts of pseudo-ginseng, 13 parts of balanophora glauca, 7 parts of borneol and 8 parts of honeycomb.
Preferably, the preparation method of the blood stasis removing, collateral dredging and bacteriostasis liquid comprises the following preparation steps:
s1: grinding all the traditional Chinese medicine raw materials except borax and dried alum into medicinal powder by stone grinding, and separately grinding and mixing the borax and the dried alum;
s2: adding the mixed and uniformly mixed borax and dried alum into a tile jar, adding an auxiliary agent, sealing the tile jar with oilpaper, storing in a dark environment, uniformly shaking the tile jar once every day at noon, and waiting for the borax and the dried alum to be completely dissolved after 33 days;
s3, adding the powder ground by stone mill into the tile jar, covering the tile jar with herba Portulacae, rhizoma Acori Calami, folium Ilicis Cornutae Immaturum, palm leaf, and folium Nelumbinis, covering with oil paper, sealing, and standing for 79 days to obtain the antibacterial liquid.
Preferably, the additive added in S2 is ethanol with a volume concentration of 95%.
Preferably, the temperature of the environment protected from light in S2 is controlled to be between 5 and 20 ℃.
Preferably, the medicinal powder in S3 is packaged in a silk yarn bag in a tight bag opening and then placed in a crock.
The invention has the following effects:
and (3) edible tulip: is cold in nature, sweet and slightly pungent in flavor, and has the effects of clearing away heat and toxic materials, eliminating carbuncle and dissipating stagnation.
Myrrh: has bitter taste and mild effect, and has effects of dispelling blood stasis, relieving swelling and pain, promoting blood circulation, relieving pain, and promoting granulation.
Ligusticum wallichii: pungent and warm, and has the effects of promoting qi circulation, resolving stagnation, dispelling pathogenic wind, removing dampness, promoting blood circulation, and relieving pain.
Rhizoma arisaematis: has effects of dispelling pathogenic wind, eliminating phlegm, relieving convulsion, and relieving pain, and can be used for treating apoplexy, paralysis, extremity spasm, headache, giddiness, infantile convulsion, and excessive phlegm.
And (3) toad venom: sweet and pungent in flavor and warm in nature, and has the effects of detoxifying, reducing swelling, tonifying heart, relieving pain and the like.
Rhizoma paridis: it is slightly cold in nature and bitter in taste, and has the functions of clearing away heat and toxic material, eliminating swelling, relieving pain, cooling liver and arresting convulsion.
Frankincense: pungent and bitter with warm nature, it has the actions of regulating qi, activating blood, relieving pain, removing toxic substance, etc. It is indicated for stagnation of qi and blood, pain in heart and abdomen, carbuncle, sore, swelling and toxin, traumatic injury, dysmenorrhea, etc.
Dried alum: sour, astringent and cold, and has the effects of eliminating phlegm, eliminating dampness, relieving diarrhea, stopping bleeding, removing toxic substances and the like.
Borax: bitter, pungent and warm in flavor, it is indicated for resolving phlegm, relieving cough and eliminating obstruction of throat.
White convergence: bitter and slightly cold, and has the effects of removing heat, killing fire toxin, dissipating stagnation of qi, promoting granulation and relieving pain.
Pseudo-ginseng: sweet, slightly bitter and warm. Has effects of removing blood stasis, stopping bleeding, promoting blood circulation, and relieving pain. Can be used for treating hemorrhage, traumatic injury, and swelling and pain due to blood stasis
Golden tortoise and lotus seed: has effects of clearing away heat and toxic materials, invigorating stomach, and relieving pain.
Borneol: pungent and bitter with cool taste, has the effects of dredging orifices, dispelling stagnated fire, removing nebula, improving eyesight, relieving swelling and pain, and the like.
Honeycomb: sweet taste and mild nature, and has the effects of counteracting toxic substances, killing parasites, dispelling pathogenic wind and relieving pain.
Due to the adoption of the technical scheme, the invention has the beneficial effects that: the edible tulip in the invention has the effects of clearing away heat and toxic materials, eliminating carbuncle and dissipating stagnation, and the myrrh has the effects of dissipating blood stasis, eliminating swelling and relieving pain, and the medicines are coordinated and matched with each other in a specific ratio and reasonably blended, so that the antibacterial liquid has the effects of remarkably dissipating blood stasis and dredging collaterals, quickly relieving pain, and having long-lasting effect without side effect.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without any inventive step, are within the scope of the present invention.
Example 1:
the stasis-dissolving collateral-dredging antibacterial liquid is prepared from the following raw materials by mass: 3g of edible tulip, 2g of myrrh, 6g of ligusticum wallichii, 3g of arisaema, 2g of venenum bufonis, 2g of rhizoma paridis, 3g of frankincense, 3g of dried alum, 4g of borax, 4g of radix ampelopsis, 2g of pseudo-ginseng, 6g of balanophora glauca, 3g of borneol and 3g of honeycomb.
The specific preparation method of the stasis-removing and collateral-dredging antibacterial liquid comprises the following steps:
s1: grinding all the traditional Chinese medicine raw materials except borax and dried alum into medicinal powder by stone grinding, and separately grinding and mixing the borax and the dried alum;
s2: adding the uniformly mixed borax and dried alum into a tile jar, adding an ethanol auxiliary agent with the volume concentration of 95%, sealing the tile jar by using oilpaper, storing in a dark environment with the temperature controlled at 5 ℃, uniformly shaking the tile jar once every noon, and completely dissolving the borax and the dried alum after 33 days;
s3, finally adding the powder packaged in a silk yarn bag in a tightening bag opening and ground by a stone mill into the tile jar, covering the tile jar with purslane, calamus, folium aconiti szechenyiani, palm leaves and lotus leaves, and then covering the tile jar with oil paper to seal the jar, and obtaining the stasis-removing collateral-dredging antibacterial liquid after 79 days.
Example 2:
the stasis-dissolving collateral-dredging antibacterial liquid is prepared from the following raw materials by mass: 15g of edible tulip, 14g of myrrh, 20g of ligusticum wallichii, 18g of arisaema, 9g of venenum bufonis, 11g of rhizoma paridis, 9g of frankincense, 13g of dried alum, 17g of borax, 16g of radix ampelopsis, 13g of pseudo-ginseng, 19g of balanophora glauca, 13g of borneol and 15g of honeycomb.
The specific preparation method of the stasis-removing and collateral-dredging antibacterial liquid comprises the following steps:
s1: grinding all the traditional Chinese medicine raw materials except borax and dried alum into medicinal powder by stone grinding, and separately grinding and mixing the borax and the dried alum;
s2: adding the uniformly mixed borax and dried alum into a tile jar, adding an ethanol auxiliary agent with the volume concentration of 95%, sealing the tile jar by using oilpaper, storing in a dark environment with the temperature controlled at 20 ℃, uniformly shaking the tile jar once every noon, and completely dissolving the borax and the dried alum after 33 days;
s3, finally adding the powder packaged in a silk yarn bag in a tightening bag opening and ground by a stone mill into the tile jar, covering the tile jar with purslane, calamus, folium aconiti szechenyiani, palm leaves and lotus leaves, and then covering the tile jar with oil paper to seal the jar, and obtaining the stasis-removing collateral-dredging antibacterial liquid after 79 days.
Example 3:
the stasis-dissolving collateral-dredging antibacterial liquid is prepared from the following raw materials by mass: 8 parts of edible tulip, 8 parts of myrrh, 12 parts of szechuan lovage rhizome, 11 parts of arisaema, 5 parts of venenum bufonis, 5 parts of rhizoma paridis, 5 parts of frankincense, 7 parts of dried alum, 10 parts of borax, 10 parts of radix ampelopsis, 7 parts of pseudo-ginseng, 13 parts of balanophora glauca, 7 parts of borneol and 8 parts of honeycomb.
The specific preparation method of the stasis-removing and collateral-dredging antibacterial liquid comprises the following steps:
s1: grinding all the traditional Chinese medicine raw materials except borax and dried alum into medicinal powder by stone grinding, and separately grinding and mixing the borax and the dried alum;
s2: adding the uniformly mixed borax and dried alum into a tile jar, adding an ethanol auxiliary agent with the volume concentration of 95%, sealing the tile jar by using oilpaper, storing in a dark environment with the temperature controlled at 15 ℃, uniformly shaking the tile jar once every noon, and completely dissolving the borax and the dried alum after 33 days;
s3, finally adding the powder packaged in a silk yarn bag in a tightening bag opening and ground by a stone mill into the tile jar, covering the tile jar with purslane, calamus, folium aconiti szechenyiani, palm leaves and lotus leaves, and then covering the tile jar with oil paper to seal the jar, and obtaining the stasis-removing collateral-dredging antibacterial liquid after 79 days.
Example 4:
the stasis-dissolving collateral-dredging antibacterial liquid is prepared from the following raw materials by mass: 5g of edible tulip, 5g of myrrh, 10g of ligusticum wallichii, 6g of arisaema, 3g of venenum bufonis, 4g of rhizoma paridis, 4g of frankincense, 5g of dried alum, 8g of borax, 7g of radix ampelopsis, 5g of pseudo-ginseng, 10g of balanophora glauca, 5g of borneol and 5g of honeycomb.
The specific preparation method of the stasis-removing and collateral-dredging antibacterial liquid comprises the following steps:
s1: grinding all the traditional Chinese medicine raw materials except borax and dried alum into medicinal powder by stone grinding, and separately grinding and mixing the borax and the dried alum;
s2: adding the uniformly mixed borax and dried alum into a tile jar, adding an ethanol auxiliary agent with the volume concentration of 95%, sealing the tile jar by using oilpaper, storing in a dark environment with the temperature controlled at 10 ℃, uniformly shaking the tile jar once every noon, and completely dissolving the borax and the dried alum after 33 days;
s3, finally adding the powder packaged in a silk yarn bag in a tightening bag opening and ground by a stone mill into the tile jar, covering the tile jar with purslane, calamus, folium aconiti szechenyiani, palm leaves and lotus leaves, and then covering the tile jar with oil paper to seal the jar, and obtaining the stasis-removing collateral-dredging antibacterial liquid after 79 days.
Example 5:
the stasis-dissolving collateral-dredging antibacterial liquid is prepared from the following raw materials by mass: 10g of edible tulip, 10g of myrrh, 15g of ligusticum wallichii, 15g of arisaema, 7g of venenum bufonis, 8g of rhizoma paridis, 7g of frankincense, 10g of dried alum, 13g of borax, 12g of radix ampelopsis, 10g of pseudo-ginseng, 15g of balanophora glauca, 10g of borneol and 10g of honeycomb.
The specific preparation method of the stasis-removing and collateral-dredging antibacterial liquid comprises the following steps:
s1: grinding all the traditional Chinese medicine raw materials except borax and dried alum into medicinal powder by stone grinding, and separately grinding and mixing the borax and the dried alum;
s2: adding the uniformly mixed borax and dried alum into a tile jar, adding an ethanol auxiliary agent with the volume concentration of 95%, sealing the tile jar by using oilpaper, storing in a dark environment with the temperature controlled at 15 ℃, uniformly shaking the tile jar once every noon, and completely dissolving the borax and the dried alum after 33 days;
s3, finally adding the powder packaged in a silk yarn bag in a tightening bag opening and ground by a stone mill into the tile jar, covering the tile jar with purslane, calamus, folium aconiti szechenyiani, palm leaves and lotus leaves, and then covering the tile jar with oil paper to seal the jar, and obtaining the stasis-removing collateral-dredging antibacterial liquid after 79 days.
Example 6:
the stasis-dissolving collateral-dredging antibacterial liquid is prepared from the following raw materials by mass: 8g of edible tulip, 5g of myrrh, 20g of ligusticum wallichii, 10g of arisaema, 6g of venenum bufonis, 5g of rhizoma paridis, 4g of frankincense, 11g of dried alum, 6g of borax, 15g of radix ampelopsis, 9g of pseudo-ginseng, 12g of balanophora glauca, 12g of borneol and 15g of honeycomb.
The specific preparation method of the stasis-removing and collateral-dredging antibacterial liquid comprises the following steps:
s1: grinding all the traditional Chinese medicine raw materials except borax and dried alum into medicinal powder by stone grinding, and separately grinding and mixing the borax and the dried alum;
s2: adding the uniformly mixed borax and dried alum into a tile jar, adding an ethanol auxiliary agent with the volume concentration of 95%, sealing the tile jar by using oilpaper, storing in a dark environment with the temperature controlled at 10 ℃, uniformly shaking the tile jar once every noon, and completely dissolving the borax and the dried alum after 33 days;
s3, finally adding the powder packaged in a silk yarn bag in a tightening bag opening and ground by a stone mill into the tile jar, covering the tile jar with purslane, calamus, folium aconiti szechenyiani, palm leaves and lotus leaves, and then covering the tile jar with oil paper to seal the jar, and obtaining the stasis-removing collateral-dredging antibacterial liquid after 79 days.
Physical and chemical detection:
the stasis-dissolving and vein-relaxing antibacterial liquid prepared in the embodiments 1-6 of the invention is subjected to statistics of physicochemical indexes, microbial indexes and microbial inhibition indexes;
the following table shows the physical and chemical index conditions of the invention:
physical and chemical indexes are shown in table 1:
item Index (I)
Stability (storage at 37 ℃ for 90 days) Stable color, no precipitate or suspended matter, no obvious change in bacteriostasis effect
pH value (25 ℃ C.) 3.0-8.0
Sealing property After the sealing test, no leakage phenomenon occurs
The following table shows the microbiological indicators of the invention:
microbiological indicators table 2:
Figure BDA0002715626540000081
the following table shows the microbial inhibition indicators of the present invention:
microbial inhibition index table 3:
item Index (I)
Average bacteriostasis rate of 15 minutes on escherichia coli ≥50%
Average bacteriostasis rate of staphylococcus aureus after 15 minutes of action ≥50%
Average bacteriostasis to candida albicans after 15 minutes of action ≥50%
In conclusion, the prepared stasis-dissolving collateral-dredging antibacterial liquid has the characteristics of stasis-dissolving collateral-dredging and pain-relieving rapidness, the physicochemical indexes of the antibacterial liquid accord with relevant regulations, and the antibacterial liquid is safe, stable and free of side effect.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.

Claims (7)

1. The blood stasis removing, collateral dredging and bacteriostasis liquid is characterized by being prepared from the following raw materials in parts by weight: 3-15 parts of edible tulip, 2-14 parts of myrrh, 6-20 parts of ligusticum wallichii, 3-18 parts of arisaema, 2-9 parts of venenum bufonis, 2-11 parts of rhizoma paridis, 3-9 parts of frankincense, 3-13 parts of dried alum, 4-17 parts of borax, 4-16 parts of radix ampelopsis, 2-13 parts of pseudo-ginseng, 6-19 parts of balanophora glauca, 3-13 parts of borneol and 3-15 parts of honeycomb.
2. The blood stasis removing, collateral dredging and bacteria inhibiting liquid as claimed in claim 1, is characterized by being prepared from the following raw materials in parts by weight: 5-10 parts of edible tulip, 5-10 parts of myrrh, 10-15 parts of ligusticum wallichii, 6-15 parts of arisaema consanguineum, 3-7 parts of venenum bufonis, 4-8 parts of rhizoma paridis, 4-7 parts of frankincense, 5-10 parts of dried alum, 8-13 parts of borax, 7-12 parts of radix ampelopsis, 5-10 parts of pseudo-ginseng, 10-15 parts of balanophora glauca, 5-10 parts of borneol and 5-10 parts of honeycomb.
3. The blood stasis removing, collateral dredging and bacteria inhibiting liquid as claimed in claim 1, is characterized by being prepared from the following raw materials in parts by weight: 8 parts of edible tulip, 8 parts of myrrh, 12 parts of szechuan lovage rhizome, 11 parts of arisaema, 5 parts of venenum bufonis, 5 parts of rhizoma paridis, 5 parts of frankincense, 7 parts of dried alum, 10 parts of borax, 10 parts of radix ampelopsis, 7 parts of pseudo-ginseng, 13 parts of balanophora glauca, 7 parts of borneol and 8 parts of honeycomb.
4. The method for preparing the stasis-dissolving and collateral-dredging bacteriostatic solution according to any one of claims 1-3, wherein the stasis-dissolving and collateral-dredging bacteriostatic solution comprises the following preparation steps:
s1: grinding all the traditional Chinese medicine raw materials except borax and dried alum into medicinal powder by stone grinding, and separately grinding and mixing the borax and the dried alum;
s2: adding the mixed and uniformly mixed borax and dried alum into a tile jar, adding an auxiliary agent, sealing the tile jar with oilpaper, storing in a dark environment, uniformly shaking the tile jar once every day at noon, and waiting for the borax and the dried alum to be completely dissolved after 33 days;
s3, adding the powder ground by stone mill into the tile jar, covering the tile jar with herba Portulacae, rhizoma Acori Calami, folium Ilicis Cornutae Immaturum, palm leaf, and folium Nelumbinis, covering with oil paper, sealing, and standing for 79 days to obtain the antibacterial liquid.
5. The method for preparing the stasis-dissolving and collateral-dredging antibacterial liquid as claimed in claim 1, wherein the auxiliary agent added in S2 is ethanol with a volume concentration of 95%.
6. The method for preparing the stasis-dissolving collateral-dredging bacteriostatic solution according to claim 1, wherein the temperature of the environment protected from light in S2 is controlled between 5-20 ℃.
7. The method for preparing the stasis-dissolving, collateral-dredging and bacteria-inhibiting liquid as claimed in claim 1, wherein the powder in S3 is packaged in a silk yarn bag in a tying bag mouth, and then put into a crock.
CN202011072723.4A 2020-10-09 2020-10-09 Blood stasis removing, collateral dredging and antibacterial liquid and preparation method thereof Pending CN111991510A (en)

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