CN104383174A - Traditional Chinese medicine for treating senile dementia - Google Patents
Traditional Chinese medicine for treating senile dementia Download PDFInfo
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- CN104383174A CN104383174A CN201410768179.5A CN201410768179A CN104383174A CN 104383174 A CN104383174 A CN 104383174A CN 201410768179 A CN201410768179 A CN 201410768179A CN 104383174 A CN104383174 A CN 104383174A
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- chinese medicine
- traditional chinese
- medicine
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- senile dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine for treating senile dementia. The medicine is mainly prepared from the following five traditional Chinese medicines in a certain ratio: epimedium herb, cistanche deserticola, glossy privet fruit, ligusticum wallichii and acorus gramineus. A conventional method for a traditional Chinese medicine preparation can be adopted, and different accessories are added into active medicine powder to prepare different conventional traditional Chinese medicine preparations such as pills, capsules or oral solutions. The medicine has the effects of reinforcing kidney to replenish essence and dissipating phlegm for resuscitation, is used for mainly treating diseases such as senile hypomnesia and the senile dementia, and has the advantages of low price, and good and convenience.
Description
Technical field
The present invention is technical field of Chinese medicines, relates to a kind of clinical Chinese medicine being used for the treatment of alzheimer disease.
Background technology
Chinese medicine is thought, deficiency of kidney-essence, deficiency of marrow-reservoir are the basic pathogenesis of alzheimer disease.Modern medicine study shows " brains " of traditional Chinese medical science indication, its modern biology basis is neuron and neurotrophic factor in brain, deficiency of marrow-reservoir is brain atrophy in Radiologic imaging, be that neuron reduces, and then it is dull-witted to cause decrease of cognitive function to occur at Pathological.This sick medical expense is high at present, the cycle is long, curative effect is undesirable.
Summary of the invention
Technical problem to be solved by this invention is, provides a kind of and has kidney tonifying, changes the Chinese medicine of the treatment alzheimer disease of effect that is turbid, that invigorate blood circulation.
In order to solve the problems of the technologies described above, the technical solution used in the present invention is: a kind of Chinese medicine for the treatment of alzheimer disease, and it comprises the crude drug of following parts by weight: Herba Epimedii 3-10 part, Herba Cistanches 6-9 part, Fructus Ligustri Lucidi 6-12 part, Rhizoma Chuanxiong 3-10 part, Rhizoma Acori Graminei 3-9 part.
Preferably, it comprises the crude drug of following parts by weight: Herba Epimedii 9 parts, Herba Cistanches 6 parts, Fructus Ligustri Lucidi 10 parts, Rhizoma Chuanxiong 6 parts, Rhizoma Acori Graminei 9 parts.
The invention has the beneficial effects as follows: the present invention treats the Chinese medicine of alzheimer disease, there is kidney tonifying, change effect that is turbid, that invigorate blood circulation, adopt plurality of Chinese to optimize prescription, effectively can treat forgetful, kind mistake, bradykinesia, speaking scarcely,taciturn in clinical treatment, have a dull expression on one's face, asthenia is thought to crouch, soreness of the waist and knees, be slow in action, be in a trance, susceptible to fear irritability, dizziness, tinnitus, the symptom such as insomnia.And there is rapid-action, that curative effect is steady, expense is few feature.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in further detail:
The Chinese medicine for the treatment of alzheimer disease of the present invention, it comprises the crude drug of following parts by weight: Herba Epimedii 3-10 part, Herba Cistanches 6-9 part, Fructus Ligustri Lucidi 6-12 part, Rhizoma Chuanxiong 3-10 part, Rhizoma Acori Graminei 3-9 part.
Preferably, it comprises the crude drug of following parts by weight: Herba Epimedii 9 parts, Herba Cistanches 6 parts, Fructus Ligustri Lucidi 10 parts, Rhizoma Chuanxiong 6 parts, Rhizoma Acori Graminei 9 parts.
Cure mainly function: kidney tonifyingization is turbid
Disease therapy: syndrome of marrow depletion due to kidney deficiency alzheimer disease
Herba Epimedii warming and recuperating the kidney-YANG; Fructus Ligustri Lucidi nourishing kidney yin; Herba Cistanches kidney-replenishing, benefiting essence-blood; Rhizoma Acori Graminei is intended to have one's ideas straightened out, Fructus Alpiniae Oxyphyllae, removing dampness, eliminating phlegm; Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling, draw to brain key on all medicines, all medicines share, nourishing kidney-yin the kidney warming is positive, and expectorant becomes silted up and suffers from a deficiency of the kidney treating both the principal and secondary aspects of a disease, play the effect that kidney tonifying marrow facilitating, blood stasis dispellingization are turbid altogether.
According to proportioning of the present invention, capsule, pill or oral liquid can be made, employing be all common process and ratio of adjuvant, no longer describe.
Capsule prepared by the Chinese medicine compound for the treatment of alzheimer disease below by the present invention (gets Herba Epimedii, Herba Cistanches, Fructus Ligustri Lucidi, Rhizoma Chuanxiong and Rhizoma Acori Graminei in proportion, in preparation, above Chinese medicine of the five flavours material is ground into fine powder, add ethanol in proper amount make soft material cross 16 mesh sieves granulate, drying, granulate, loads No. 0 capsule and obtains patent medicine, specification: 0.5g/ grain) treat the clinical observation test of alzheimer disease, set forth further the effect of medicine of the present invention.
1. physical data: this group ratio patients with Alzheimer disease, all comes from the case of outpatient service.Wherein man 25 example, female 47 example, age 61-85 year, 72.79 ± 6.76 years old mean age, average course of disease 28.75 ± 14.22 months.
2. diagnostic criteria:
Western medicine diagnose standard is with reference to the diagnostic criteria of American Psychiatric association " mental sickness diagnostic & statistical manual " (the 4th edition) (DSM-IV) [2].
Standards of Chinese Medical Syndrome Differentiation is with reference to " National Standard of the People's Republic of China-tcm clinical practice diagnosis and treatment term syndrome part " (GB/T 16751.2-1997).
3. Therapeutic Method: oral every day 2 times, each 1 bag, serveing on one month is a course for the treatment of, generally need take 3-6 and take a favorable turn the course for the treatment of, and as adhered to, Long-term taking medicine can reach better curative effect.
4. efficacy assessment standard: before therapeutic index=(after treatment the front integration of integration-treatment)/treatment × 100%.Effective: therapeutic index >=20%; Progressive: therapeutic index 10% ~ 20%; Without regressing: therapeutic index 0% ~ 10%; Invalid: therapeutic index <0%.
Model case:
Example 1
Liu XX, female, 64 years old, people from Tianjin, summer in 2011 went to a doctor because of hypomnesis 2 years, and with granule of the present invention after 3 months, memory is improved and conscious lumbago and skelalgia symptom is clearly better.
Example 2
Zhao XX, man, 65 years old, people from Tianjin, medical outpatient service in 2012, plain memory continuous decrease more than 1 year, once diagnosis and treatment were not imitated in many ways, took this capsule, and take a turn for the better through the treatment patient memory of 6 months, it is many that the crown grows black hair.
Example 3
Yu XX, man, 72 years old, Shanghai people, retirement looked after granddaughter in this locality.Main suit's dizziness companion memory declines more than 2 years gradually, and strange land many hospital administrations of going to a doctor are invalid, through asking about, in March, 2012, apply pill of the present invention, when 3 months for oral administration, patient feels dizzy obviously improvement, take medicine 6 months time without dizziness, and memory comparatively before take a turn for the better.
After 3-6 course of therapy, statistics curative effect is as follows: effective 31 examples, progressive 29 examples, without 10 examples that regress, and invalid 2 examples, total effective rate 83.3%.Current clinical application compound of Chinese medicine alzheimer disease achieves the curative effect of affirmative, reaches the object of relief of symptoms and clinical economics.
Above-described embodiment is only for illustration of technological thought of the present invention and feature, its object is to enable those skilled in the art understand content of the present invention and implement according to this, only can not limit the scope of the claims of the present invention with the present embodiment, namely the equal change done of all disclosed spirit or modification, still drop in the scope of the claims of the present invention.
Claims (2)
1. treat a Chinese medicine for alzheimer disease, it is characterized in that, it comprises the crude drug of following parts by weight: Herba Epimedii 3-10 part, Herba Cistanches 6-9 part, Fructus Ligustri Lucidi 6-12 part, Rhizoma Chuanxiong 3-10 part, Rhizoma Acori Graminei 3-9 part.
2. the Chinese medicine for the treatment of alzheimer disease according to claim 1, is characterized in that, it comprises the crude drug of following parts by weight: Herba Epimedii 9 parts, Herba Cistanches 6 parts, Fructus Ligustri Lucidi 10 parts, Rhizoma Chuanxiong 6 parts, Rhizoma Acori Graminei 9 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410768179.5A CN104383174A (en) | 2014-12-12 | 2014-12-12 | Traditional Chinese medicine for treating senile dementia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410768179.5A CN104383174A (en) | 2014-12-12 | 2014-12-12 | Traditional Chinese medicine for treating senile dementia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104383174A true CN104383174A (en) | 2015-03-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410768179.5A Pending CN104383174A (en) | 2014-12-12 | 2014-12-12 | Traditional Chinese medicine for treating senile dementia |
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| CN (1) | CN104383174A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105288136A (en) * | 2015-11-28 | 2016-02-03 | 青岛麦瑞特医药技术有限公司 | Medicine composition for treating alzheimer disease and preparation method of medicine composition |
| CN112022941A (en) * | 2020-10-15 | 2020-12-04 | 天津中医药大学第二附属医院 | Chinese medicinal composition freeze-dried powder and preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1178119A (en) * | 1997-10-13 | 1998-04-08 | 首都医科大学宣武医院 | Traditional Chinese medicine preparation for treating senile dementia |
| CN101229349A (en) * | 2008-01-29 | 2008-07-30 | 田金洲 | Medicine for treating senile dementia and preparing method thereof |
-
2014
- 2014-12-12 CN CN201410768179.5A patent/CN104383174A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1178119A (en) * | 1997-10-13 | 1998-04-08 | 首都医科大学宣武医院 | Traditional Chinese medicine preparation for treating senile dementia |
| CN101229349A (en) * | 2008-01-29 | 2008-07-30 | 田金洲 | Medicine for treating senile dementia and preparing method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 龙斯玥，等。: "补肾活血法治疗老年性痴呆的研究进展", 《世界中医药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105288136A (en) * | 2015-11-28 | 2016-02-03 | 青岛麦瑞特医药技术有限公司 | Medicine composition for treating alzheimer disease and preparation method of medicine composition |
| CN112022941A (en) * | 2020-10-15 | 2020-12-04 | 天津中医药大学第二附属医院 | Chinese medicinal composition freeze-dried powder and preparation method and application thereof |
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Application publication date: 20150304 |
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