CN104189478A - Traditional Chinese medicine composition for treating cervical spondylosis and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating cervical spondylosis and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the field of traditional Chinese medicine, relates to a traditional Chinese medicine composition for treating cervical spondylosis and a preparation method thereof, and aims to overcome the defect that conventional chemotherapeutic medicine for cervical spondylosis is relatively high in toxic side effect, and not good in curative effect. The traditional Chinese medicine composition comprises the following components in parts by weight: 10-50 parts of fructus forsythiae, 10-20 parts of szechuan lovage rhizome, 5-20 parts of mint, 5-15 parts of Indian buead, 5-10 parts of officinal magnolia bark, 5-15 parts of lycopodium clavatum, 5-15 parts of rhizoma drynariae, 6-10 parts of pollen typhae, 5-15 parts of Chinese wolfberry, 9-15 parts of rhizoma polygonati, 9-15 parts of lamiophlomis rotata, 5-15 parts of epimedium, 1.5-9 parts of safflower, 5.5-15 parts of dandelion, 6-9 parts of platycodon root, and 10-15 parts of liquorice. The traditional Chinese medicine composition has excellent curative effect on treating or preventing cervical spondylosis, is low in medicine side effect, and has remarkable clinical popularization value.
Description
Technical field
The invention belongs to field of medicaments, be specifically related to a kind of Chinese medicine composition for the treatment of cervical spondylosis and preparation method thereof.
Background technology
Cervical spondylosis is one of common ailment of middle-aged and old frequently-occurring disease.According to statistics, its sickness rate raise with the age.In the developing of cervical spondylosis, chronic strain is primary arch-criminal, the damage of long-term local muscle, ligament, joint capsule, can cause local hemorrhage edema, the change that is inflamed, engenders inflammation machine at the position of pathological changes, and form hyperosteogeny, affect local nerve and blood vessel.Wound is the pathogenetic direct factor of cervical vertebra.Often, wound forefathers, had pathological changes in various degree, made cervical vertebra in highly dangerous state, the direct induced symptom of wound occurs.Bad posture is other one large reason of cervical spine injury.The work of bowing for a long time, lies on a bed and sees TV, reading, likes high pillow, long-time operation computer, and violent rotation cervical region or head are slept on the car travelling, and these bad postures all can make musculi colli in long-term fatigue state, easily damage.The dysplasia of cervical vertebra or defect are also one of cervical spondylosis generation assignable causes, and ethnic group vertebral canal volume with respect to occidentals in Asia is less, and compression of spinal cord more easily occurs, and produce symptom.One-sided vertebral artery lack as patient, the incidence rate of vertebral artery type of cervical spondylosis is almost 100%, the sooner or later of difference.In addition, basilar impression, congenitally melt that vertebra, root pipe are narrow, little canalis spinalis etc. is all congenital dysplasias, is also this pathogenetic major reason.
Mainly there is two kinds of operative treatment and non-operative treatments in the at present treatment of cervical spondylosis, operative treatment due to exist medical expense expensive, take stopgap measures refractory this, easily recurrence etc. shortcoming, it is not the first-selection of Patients with Cervical Spondylopathy.In fact more than 95% case of cervical spondylosis all can be cured or is clearly better by non-operative treatment.Non-operative treatment comprises the methods such as Chinese and western drugs, acupuncture, massage, physical therapy, traction, and the medicine for the treatment of cervical spondylopathy comprises Western medicine and Chinese medicine two large divisions.If the drug main anti-inflammatory analgesic of western medicine cervical spondylopathy is main nonsteroidal analgesics, as chondroitin sulfate A, vitamin E, JINGTONGLING etc., such medicine is conventionally rapid-action, but effect is difficult to lastingly, needs long-term prescription.Chinese medicine has abundant medication experience and tcm theory aspect treatment cervical spondylosis, and cervical spondylosis belongs to Chinese medicine " arthromyodynia " category.Clinical syndrome differentiation is mainly divided into two types of caused by liver and kidney deficiency, anemofrigid-damp arthralgia, the Main Function of the clinical Chinese medicine for cervical spondylosis is soothing the channels and quicking the network vessels, blood circulation promoting and blood stasis dispelling and expelling wind and removing dampness etc., as cold-dampness numbness myelopathy selects Aconiti Decoction, close Yiyiren Decoction plus-minus, qi depression to blood stasis myelopathy selects Traditional Chinese medicine decoction for treating-ache and expelling atagnate etc. all to obtain good clinical therapeutic efficacy.But the Chinese medicine clinical effectiveness for the treatment of at present cervical spondylosis is not good, the object of the invention is to provide a kind of effect comprehensive, the Chinese medicine composition of the treatment cervical spondylosis that clinical effectiveness is good.
Summary of the invention
Large in order to overcome existing cervical spondylosis chemotherapeutic agent toxic and side effects, the prior art that therapeutic effect is not good enough is not enough, the invention provides a kind of Chinese medicine composition for the treatment of cervical spondylosis, this Chinese medicine composition is good for the therapeutic effect of cervical spondylosis, and toxic and side effects is little in use procedure, there is good potential applicability in clinical practice.
The present invention is achieved through the following technical solutions above-mentioned technical purpose:
A Chinese medicine composition that is used for the treatment of cervical spondylosis, it is mainly made by following raw material: Fructus Forsythiae 10-50 part, Rhizoma Chuanxiong 10-20 part, Herba Menthae 5-20 part, Poria 5-15 part, Cortex Magnoliae Officinalis 5-10 part, Herba Lycopodii 5-15 part, Rhizoma Drynariae 5-15 part, Pollen Typhae 6-10 part, Fructus Lycii 5-15 part, Rhizoma Polygonati 9-15 part, Radix Lamiophlomidis Rotatae 9-15 part, Herba Epimedii 5-15 part, Flos Carthami 1.5-9 part, Herba Taraxaci 5.5-15 part, Radix Platycodonis 6-9 part, Radix Glycyrrhizae 10-15 part.
Chinese medicine composition of the present invention on Chinese medicinal components is selected, take except long-pending numbness, dispersing wind and cold, wind-damp dispelling, bone and muscle strengthening be main standard, described Chinese medicine is all used as medicine with its conventional agents area.Zoopery shows to have significant antiinflammatory and analgesic effect after Chinese medicine composition combination of the present invention.Improvement effect according to pharmaceutical composition to above-mentioned activity, the present invention has carried out preferably the parts by weight of above-mentioned all taste Chinese medicine, as a preferred embodiment of the present invention, Chinese medicine composition of the present invention is mainly made by the raw material of following weight portion: 30 parts of Fructus Forsythiaes, 15 parts of Rhizoma Chuanxiongs, 15 parts of Herba Menthaes, 10 parts, Poria, 8 parts of Cortex Magnoliae Officinalis, 10 parts of Herba Lycopodiis, 10 parts of Rhizoma Drynariae, 6 parts of Pollen Typhaes, 10 parts of Fructus Lyciis, 12 parts of Rhizoma Polygonatis, 12 parts of Radix Lamiophlomidis Rotataes, 10 parts of Herba Epimedii, 5.5 parts, Flos Carthami, 10 parts of Herba Taraxacis, 8 parts of Radix Platycodoniss, 12 parts, Radix Glycyrrhizae.
The present invention also provides a kind of preparation method of Chinese medicine composition described above, it mainly comprises following step: get the above-mentioned Chinese crude drug of recipe quantity and be broken into coarse powder, according to 4～9 times of coarse powder gross weight, adding volumetric concentration is 40%～95% alcoholic solution, reflux, extract, three times, return time is 2～5h, filters, filtrate recycling ethanol, cold filtration, washes with water, after being dried, obtains Chinese medical concrete; Those skilled in the art can be at the technical conventional Chinese medicine pharmaceutical dosage form clinically for preparing of this preparation method, as tablet, mixture, capsule etc.
The present invention also asks for protection the purposes of above-mentioned Chinese medicine composition in preparation treatment cervical spondylosis medicine.Pharmaceutical composition of the present invention, when treatment cervical spondylosis, demonstrates significant anti-inflammatory and antalgic, activating blood circulation to dissipate blood stasis activity.Drug effect embodiment 7 of the present invention shows; with model group comparison; the low middle Senior Three of a Chinese medicine composition of the present invention dosage group all can significantly reduce the ear swelling value of dimethylbenzene induced mice; and the ear swelling value of Chinese medicine composition xylol induced mice of the present invention reduces effect and is greater than JINGFUKANG KELI or JINGTONGLING group; this shows that Chinese medicine composition of the present invention has significant antiinflammatory action; for cervical vertebra the disease condition of reduction of patient fundamentally while treating; and its antiphlogistic effects exists significant dose-effect relationship, antiphlogistic effects is better than existing medicine.Drug effect embodiment 8 of the present invention shows; mice licks foot response latency time showing; with model group comparison; after administration after 1h and 2h; the incubation period that the mice of each administration group of Chinese medicine composition of the present invention is added foot reaction, there is the difference of significance or utmost point significance in model group not only, and also have the difference of significance with JINGFUKANG KELI or JINGTONGLING group.This shows that this Chinese medicine composition of the present invention can extend adding the sufficient response latency that mice stimulates hot plate, and its analgesic activity is better than existing treatment of cervical spondylopathy medicine.
In a word, pharmaceutical composition of the present invention, aspect treatment cervical spondylosis, compared with prior art has following advantage:
1) compare with positive control drug JINGFUKANG KELI or JINGTONGLING; pharmaceutical composition Chinese medicine composition of the present invention is more remarkable at antiinflammatory and ease pain; this shows that the present composition has significant synergism in treatment of cervical spondylopathy; not only can significantly improve the symptom of cervical spondylosis; can also delay the development of cervical spondylosis, reduce the generation of complication.
2) compare with the chemotherapeutic agent of current treatment cervical spondylosis, Chinese medicine composition of the present invention is natural pure Chinese medicinal preparation, untoward reaction and side effect significantly reduce, and Chinese medicine composition effect of the present invention is more comprehensive, medication effect is better, significantly improved the compliance of Patients with Cervical Spondylopathy, and improved patient's quality of life.
3) existing treatment of cervical spondylopathy medicine cervical spondylosis initial stage therapeutic effect still can, but along with obvious drug resistance problem all appears in the prolongation for the treatment of time, the therapeutic effect of cervical spondylosis declines.In Chinese medicine composition of the present invention, contain multi-medicament component, action target spot is numerous, has effectively solved the Commpensation And Adaptation for the treatment of of cervical spondylopathy medicine, its to the therapeutic effect of cervical spondylosis not because treatment time extends and to decline.
The specific embodiment
By specific embodiment, further describe the present invention below, the present invention is not limited only to following examples.Within the scope of the invention or within not departing from content of the present invention, spirit and scope, the change that the present invention is carried out, combination or replacement, be apparent for a person skilled in the art, and be included within the scope of the present invention.
First's Chinese medicinal composition preparation of the present invention and preparation method thereof
Embodiment 1 Chinese medicine composition tablet of the present invention
A Chinese medicine composition that is used for the treatment of cervical spondylosis, it is mainly made by following raw material: Fructus Forsythiae 100g, Rhizoma Chuanxiong 100g, Herba Menthae 50g, Poria 50g, Cortex Magnoliae Officinalis 50g, Herba Lycopodii 50g, Rhizoma Drynariae 5, Pollen Typhae 60g, Fructus Lycii 50g, Rhizoma Polygonati 90g, Radix Lamiophlomidis Rotatae 90g, Herba Epimedii 50g, Flos Carthami 1.50g, Herba Taraxaci 5.50g, Radix Platycodonis 60g, Radix Glycyrrhizae 100g.
The preparation method of described Chinese medicine composition mainly comprises following step: get the above-mentioned Chinese crude drug of recipe quantity and be broken into coarse powder, according to 4 times of coarse powder gross weight, adding volumetric concentration is 95% alcoholic solution, reflux, extract, three times, return time is 5h, filter filtrate recycling ethanol, cold filtration, wash with water, after being dried, obtain Chinese medical concrete; Those skilled in the art can be at the technical Chinese medicine composition tablet for preparing of this preparation method.
Embodiment 2 Chinese medicinal composition capsules agent of the present invention
A Chinese medicine composition that is used for the treatment of cervical spondylosis, it is mainly made by following raw material: Fructus Forsythiae 500g, Rhizoma Chuanxiong 200g, Herba Menthae 200g, Poria 150g, Cortex Magnoliae Officinalis 100g, Herba Lycopodii 150g, Rhizoma Drynariae 150g, Pollen Typhae 100g, Fructus Lycii 150g, Rhizoma Polygonati 150g, Radix Lamiophlomidis Rotatae 150g, Herba Epimedii 150g, Flos Carthami 90g, Herba Taraxaci 150g, Radix Platycodonis 90g, Radix Glycyrrhizae 150g.
The preparation method of described Chinese medicine composition mainly comprises following step: get the above-mentioned Chinese crude drug of recipe quantity and be broken into coarse powder, according to 6 times of coarse powder gross weight, adding volumetric concentration is 50% alcoholic solution, reflux, extract, three times, return time is 3h, filter filtrate recycling ethanol, cold filtration, wash with water, after being dried, obtain Chinese medical concrete; Those skilled in the art can prepare Chinese medicinal composition capsules agent this preparation method is technical.
Embodiment 3 Chinese medicine composition mixture of the present invention
A Chinese medicine composition that is used for the treatment of cervical spondylosis, it is mainly made by following raw material: Fructus Forsythiae 300g, Rhizoma Chuanxiong 150g, Herba Menthae 150g, Poria 100g, Cortex Magnoliae Officinalis 80g, Herba Lycopodii 100g, Rhizoma Drynariae 100g, Pollen Typhae 60g, Fructus Lycii 100g, Rhizoma Polygonati 120g, Radix Lamiophlomidis Rotatae 120g, Herba Epimedii 100g, Flos Carthami 5.50g, Herba Taraxaci 100g, Radix Platycodonis 80g, Radix Glycyrrhizae 120g.
The preparation method of described Chinese medicine composition mainly comprises following step: get the above-mentioned Chinese crude drug of recipe quantity and be broken into coarse powder, according to 7 times of coarse powder gross weight, adding volumetric concentration is 75% alcoholic solution, reflux, extract, three times, return time is 2h, filter filtrate recycling ethanol, cold filtration, wash with water, after being dried, obtain Chinese medical concrete; Those skilled in the art can be at the technical Chinese medicine composition mixture for preparing of this preparation method.
Embodiment 4 Chinese medicine composition tablet of the present invention
A Chinese medicine composition that is used for the treatment of cervical spondylosis, it is mainly made by following raw material: Fructus Forsythiae 20kg, Rhizoma Chuanxiong 13kg, Herba Menthae 16kg, Poria 8kg, Cortex Magnoliae Officinalis 9kg, Herba Lycopodii 12kg, Rhizoma Drynariae 9kg, Pollen Typhae 8kg, Fructus Lycii 9kg, Rhizoma Polygonati 13kg, Radix Lamiophlomidis Rotatae 11kg, Herba Epimedii 14kg, Flos Carthami 7kg, Herba Taraxaci 6kg, Radix Platycodonis 7kg, Radix Glycyrrhizae 11kg.
The preparation method of described Chinese medicine composition mainly comprises following step: get the above-mentioned Chinese crude drug of recipe quantity and be broken into coarse powder, according to 4.5 times of coarse powder gross weight, adding volumetric concentration is 55% alcoholic solution, reflux, extract, three times, return time is 4h, filter filtrate recycling ethanol, cold filtration, wash with water, after being dried, obtain Chinese medical concrete; Those skilled in the art can be at the technical Chinese medicine composition tablet for preparing of this preparation method.
Embodiment 5 Chinese medicinal composition capsules agent of the present invention
A Chinese medicine composition that is used for the treatment of cervical spondylosis, it is mainly made by following raw material: Fructus Forsythiae 25kg, Rhizoma Chuanxiong 17kg, Herba Menthae 8kg, Poria 15kg, Cortex Magnoliae Officinalis 5kg, Herba Lycopodii 9kg, Rhizoma Drynariae 11kg, Pollen Typhae 7kg, Fructus Lycii 9kg, Rhizoma Polygonati 14kg, Radix Lamiophlomidis Rotatae 13kg, Herba Epimedii 12kg, Flos Carthami 5kg, Herba Taraxaci 6kg, Radix Platycodonis 8kg, Radix Glycyrrhizae 12kg.
The preparation method of described Chinese medicine composition mainly comprises following step: get the above-mentioned Chinese crude drug of recipe quantity and be broken into coarse powder, according to 9 times of coarse powder gross weight, adding volumetric concentration is 90% alcoholic solution, reflux, extract, three times, return time is 4h, filter filtrate recycling ethanol, cold filtration, wash with water, after being dried, obtain Chinese medical concrete; Those skilled in the art can prepare Chinese medicinal composition capsules agent this preparation method is technical.
Embodiment 6 Chinese medicine composition mixture of the present invention
A Chinese medicine composition that is used for the treatment of cervical spondylosis, it is mainly made by following raw material: Fructus Forsythiae 35kg, Rhizoma Chuanxiong 15kg, Herba Menthae 17kg, Poria 14kg, Cortex Magnoliae Officinalis 8kg, Herba Lycopodii 10kg, Rhizoma Drynariae 10kg, Pollen Typhae 8kg, Fructus Lycii 9kg, Rhizoma Polygonati 11kg, Radix Lamiophlomidis Rotatae 13kg, Herba Epimedii 14kg, Flos Carthami 4kg, Herba Taraxaci 13kg, Radix Platycodonis 7kg, Radix Glycyrrhizae 13kg.
The preparation method of described Chinese medicine composition mainly comprises following step: get the above-mentioned Chinese crude drug of recipe quantity and be broken into coarse powder, according to 5 times of coarse powder gross weight, adding volumetric concentration is 85% alcoholic solution, reflux, extract, three times, return time is 3.5h, filter filtrate recycling ethanol, cold filtration, wash with water, after being dried, obtain Chinese medical concrete; Those skilled in the art can be at the technical Chinese medicine composition mixture for preparing of this preparation method.
Second portion Chinese medicine composition pharmacodynamic study of the present invention
Embodiment 7 Chinese medicine composition xylol of the present invention causes the impact of mice ear
Get 72 of healthy ICR mices, male and female half and half, be divided at random 6 groups, 12/group, be model group, JINGFUKANG KELI group (Chengde JingFuKang pharmacy Group Co.,Ltd, lower same), JINGTONGLING group (Yantai Zhichu Pharmaceutical Co., Ltd.), Chinese medicine composition of the present invention (making by Chinese medicine composition prescription and preparation technology described in embodiment 3) low dose group, middle dosage group and high dose group.1 time/d of every ig administration; Successive administration 14d, evenly smears dimethylbenzene 0.03mL/ at mouse right ear after 60min after last medicine and only causes swollenly, cuts ears and beat auricle and weigh after 2h, calculates ear swelling value (mg).Ear swelling value=auris dextra weight-left ear weight.
The impact of table 1 Chinese medicine composition xylol of the present invention induced mice ear swelling
| Group | Dosage (g/kg) | Ear swelling value (mg) |
| Model group | - | 12.05±3.15 |
| JINGFUKANG KELI group | 1.5 | 9.24±1.37 |
| JINGTONGLING group | 0.625 | 8.63±1.96 * |
| Chinese medicine composition low dose group | 1.25 | 6.85±1.06 ** |
| Dosage group in Chinese medicine composition | 2.5 | 6.21±1.28 ** |
| Chinese medicine composition high dose group | 5 | 5.31±0.95 ** |
Note: with model group comparison,
*p < 0.05,
*p < 0.01
Result shows; with model group comparison; the low middle Senior Three of a Chinese medicine composition of the present invention dosage group all can significantly reduce the ear swelling value of dimethylbenzene induced mice; and the ear swelling value of Chinese medicine composition xylol induced mice of the present invention reduces effect and is greater than JINGFUKANG KELI or JINGTONGLING group; this shows that Chinese medicine composition of the present invention has significant antiinflammatory action; for cervical vertebra the disease condition of reduction of patient fundamentally while treating; and its antiphlogistic effects exists significant dose-effect relationship, antiphlogistic effects is better than existing medicine.
The impact of embodiment 8 Chinese medicine composition of the present invention on mice hot-plate analgesia
Body weight 20g left and right female mice is placed on hot plate dolorimeter, (licking metapedes time <5s or >30s throws aside to screen 90 of qualified ♀ mices, for preventing foot, scald, also should establish deadline, be generally 60s), be the threshold of pain index incubation period that the mice of take is added metapedes reaction, get 72 jennies, be divided into 6 groups, 12/group, i.e. model group, JINGFUKANG KELI, JINGTONGLING group, Chinese medicine composition of the present invention (making by Chinese medicine composition prescription and preparation technology described in embodiment 1) low dose group, middle dosage group and high dose group.Each group is gastric infusion, and 1 times/day, dosage is as shown in table 2, after successive administration 14d, and the time that after mensuration last medicine, 60min, 120min add foot reaction.
Table 2 Chinese medicine composition of the present invention is on licking the impact of foot response latency in the experiment of mice hot-plate analgesia
Note: with model group comparison,
*p < 0.05,
*p < 0.01
By table 2 mice, lick foot response latency time showing; with model group comparison; after administration after 1h and 2h; the incubation period that the mice of each administration group of Chinese medicine composition of the present invention is added foot reaction, there is the difference of significance or utmost point significance in model group not only, and also have the difference of significance with JINGFUKANG KELI or JINGTONGLING group.This shows that this Chinese medicine composition of the present invention can extend adding the sufficient response latency that mice stimulates hot plate, and its analgesic activity is better than existing treatment of cervical spondylopathy medicine.
The clinical therapeutic efficacy of embodiment 9 Chinese medicine composition of the present invention to cervical vertebra syndrome
1, clinical statistics is learned basic document: choose in June, 2013-August patient 80 examples medical in the People's Hospital, Anhui Province, be in hospital or outpatient, between basic 25～50 years old age, the mean age is 44 years old, and wherein the elder of the course of disease is 5 years, the shortest person March; Through CT and X-ray, turn out to be prolapse of lumbar intervertebral disc.Random minute two groups, matched group and treatment group, two groups at age, sex, coincident with severity degree of condition without big-difference too, there is comparability.
2, therapeutic modality: matched group adopts massages and the treatment of Western medicine ibuprofen tablet.Treatment group adopts the pharmaceutical preparation treatment of embodiments of the invention 3 preparations.Administration group, the 1500mg crude drug amount of at every turn taking medicine, every day three times, matched group is taken 200mg on massage basis, every day three times.Every 10 days is a course for the treatment of, treats observe the curative effect after three courses for the treatment of.
3, clinical development standard:
Effective: after treatment, pain numbness obviously alleviates.
Invalid: after treatment, symptom is without significant change.
4, therapeutic effect
Therapeutic effect is in Table 3, and result shows, the clinical therapeutic efficacy of Chinese medicine composition of the present invention is significantly better than existing massage and the treatment of Western medicine ibuprofen tablet, and the present invention is pure Chinese medicinal preparation, has no side effect, and has good potential applicability in clinical practice.
The clinical therapeutic efficacy of table 3 Chinese medicine composition of the present invention to cervical vertebra syndrome
| Group | Age | Case load | Effective number of cases | Invalid number of cases | Total effective rate |
| Treatment group | 25-50 | 40 | 38 | 2 | 95％ |
| Matched group | 25-50 | 40 | 28 | 12 | 70％ |
Claims (5)
1. a Chinese medicine composition for the treatment of cervical spondylosis, is characterized in that, it is mainly made by the raw material of following weight portion: Fructus Forsythiae 10-50 part, Rhizoma Chuanxiong 10-20 part, Herba Menthae 5-20 part, Poria 5-15 part, Cortex Magnoliae Officinalis 5-10 part, Herba Lycopodii 5-15 part, Rhizoma Drynariae 5-15 part, Pollen Typhae 6-10 part, Fructus Lycii 5-15 part, Rhizoma Polygonati 9-15 part, Radix Lamiophlomidis Rotatae 9-15 part, Herba Epimedii 5-15 part, Flos Carthami 1.5-9 part, Herba Taraxaci 5.5-15 part, Radix Platycodonis 6-9 part, Radix Glycyrrhizae 10-15 part.
2. Chinese medicine composition as claimed in claim 1, is characterized in that, it is mainly made by the raw material of following weight portion: 30 parts of Fructus Forsythiaes, 15 parts of Rhizoma Chuanxiongs, 15 parts of Herba Menthaes, 10 parts, Poria, 8 parts of Cortex Magnoliae Officinalis, 10 parts of Herba Lycopodiis, 10 parts of Rhizoma Drynariae, 6 parts of Pollen Typhaes, 10 parts of Fructus Lyciis, 12 parts of Rhizoma Polygonatis, 12 parts of Radix Lamiophlomidis Rotataes, 10 parts of Herba Epimedii, 5.5 parts, Flos Carthami, 10 parts of Herba Taraxacis, 8 parts of Radix Platycodoniss, 12 parts, Radix Glycyrrhizae.
3. the Chinese medicine composition as described in as arbitrary in claim 1 or 2, is characterized in that, it is mixture, tablet or capsule.
4. a method of preparing Chinese medicine composition as claimed in claim 3, it is characterized in that, it comprises the following steps:: get the above-mentioned Chinese crude drug of recipe quantity and be broken into coarse powder, according to 4～9 times of coarse powder gross weight, adding volumetric concentration is 40%～95% alcoholic solution, reflux, extract, three times, return time is 2～5h, filter filtrate recycling ethanol, cold filtration, wash with water, after being dried, obtain Chinese medical concrete.
5. Chinese medicine composition claimed in claim 1 is treated purposes in cervical spondylosis medicine in preparation.
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| CN104587137A (en) * | 2015-01-09 | 2015-05-06 | 王深涧 | Traditional Chinese medicine composition for treating aseptic cervicoshoulder myofascitis and preparation method thereof |
| CN106266566A (en) * | 2016-09-10 | 2017-01-04 | 四川金堂海纳生物医药技术研究所 | A kind of pill medicine treating cervical spondylosis and preparation method thereof |
| CN107496834A (en) * | 2017-09-07 | 2017-12-22 | 成都兴倍加生物科技有限责任公司 | A kind of capsule medicine for treating cervical spondylopathy and preparation method thereof |
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| CN1418696A (en) * | 2002-12-13 | 2003-05-21 | 马新华 | Traditional Chinese medicine prepn. for treating cervical vertebra disease |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104587137A (en) * | 2015-01-09 | 2015-05-06 | 王深涧 | Traditional Chinese medicine composition for treating aseptic cervicoshoulder myofascitis and preparation method thereof |
| CN106266566A (en) * | 2016-09-10 | 2017-01-04 | 四川金堂海纳生物医药技术研究所 | A kind of pill medicine treating cervical spondylosis and preparation method thereof |
| CN107496834A (en) * | 2017-09-07 | 2017-12-22 | 成都兴倍加生物科技有限责任公司 | A kind of capsule medicine for treating cervical spondylopathy and preparation method thereof |
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Application publication date: 20141210 |