CN101607007B - Traditional Chinese medicine preparation for treating cerebral circulation insufficiency - Google Patents

Traditional Chinese medicine preparation for treating cerebral circulation insufficiency Download PDF

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CN101607007B
CN101607007B CN2009100673388A CN200910067338A CN101607007B CN 101607007 B CN101607007 B CN 101607007B CN 2009100673388 A CN2009100673388 A CN 2009100673388A CN 200910067338 A CN200910067338 A CN 200910067338A CN 101607007 B CN101607007 B CN 101607007B
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赵晓光
陈雨
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Abstract

The invention relates to a traditional Chinese medicine preparation for treating cerebral circulation insufficiency, belonging to medicines. The traditional Chinese medicine preparation is prepared by finished products of natural traditional Chinese medicines which are prepared by and bought from a medicine company, and comprises formulas such as saffron, keel, turtle shell, fructus forsythiae, dried orange peel, mangnolia officinalis, manchurian wildginger, angelica, pillis ophidiae, native copper, cassia twig, radix angelicae pubescentis, centipede, notopterygium root, etc. The traditional Chinese medicine preparation is prepared by a method comprising: the herbal pieces prepared for decoction is soaked in oil, and the medicine is successively put into the herbal pieces; 4kg of sesame oil and 2kg of Zhangdan are used in every package of preparation; after the preparation is boiled in an oil pan by slow fire, the medicine is added into the pan and boiled for 30min by the slow fire; the residual of the herbal pieces prepared for decoction is extracted and filtered out; under the condition that the oil is boiled, the Zhangdan is added into the oil and stirred for 20-30min, and can be immediately taken out of the pan after becoming light coffee color; after being cooled, paste preparation can be obtained; a piece of paste is formed by every 15g of the paste preparation and is packed into ointment according to the novel technique. The traditional Chinese medicine preparation has obvious treating effect for the patients, short treating time, rapid effect, low expense, good generalizing property and remarkable effect on improving the health of the patients.

Description

A kind of Chinese medicine unguentum for the treatment of cerebral blood supply insufficiency
Technical field
The present invention relates to pharmaceutical, particularly a kind of Chinese medicine preparation for the treatment of cerebral blood supply insufficiency.
Background technology
Cerebral blood supply insufficiency is meant that a variety of causes causes brain blood supply insufficiency to occur, causes the brain hypoxic-ischemic and the handicapped disease of brain occurs.The chronic insufficient cerebral blood supply sickness rate is very high, belongs to the frequently-occurring disease of middle-aged and elderly people.According to statistics, there is 2/3 people to suffer from the different chronic insufficient cerebral blood supply disease of degree in the mid-aged population.The home and abroad physician also finds through big quantity research, in the patient of " senile dementia " and " cerebral infarction ", morbidity all once has the existence of chronic insufficient cerebral blood supply disease early stage for a long time, if treat, also may cause the generation of " senile dementia " and " cerebral infarction " to chronic insufficient cerebral blood supply is untimely.
Brain is the vitals of human body, and oxygen consumption is relatively large, and the weight of brain approximately only accounts for 2% of body wt, but oxygen consumption but accounts for 20% of whole body oxygen consumption.The required oxygen of brain is all by blood supply, so must there be enough blood supply brains could normal activity.In a single day cerebral blood flow reduces, and the oxygen supply function of brain cell also reduces immediately; The local brain tissue necrosis if a certain part blood flow of brain is blocked within a short period of time fully, can take place, Here it is cerebral infarction as long as second surplus the ischemia 10 will cause that the function of brain changes in cerebral tissue; If blood supply in brain is not to block fully but reduce at leisure, Here it is chronic insufficient cerebral blood supply.
To the treatment of the various symptoms of above-mentioned cerebral blood supply insufficiency, take medicine clinically or inject that often effect is undesirable, even can fail.In a word, also lack effective treatment means treating cerebral blood supply insufficiency clinically at present, the problem of above-mentioned existence need further be solved.
Content of the present invention
The object of the invention is to provide a kind of Chinese medicine preparation for the treatment of cerebral blood supply insufficiency effectively, solves to treat cerebral blood supply insufficiency at present clinically and lack effective treatment means, the clinical problem of taking medicine or injecting poor effect often or failure.
Technical scheme of the present invention: the domestic and international problem of the big quantity research cerebral blood supply insufficiency of physician clinically, its cause of disease complexity, the sickness rate height, particularly often appearance dizziness repeatedly of middle-aged and elderly people of a lot of people is arranged in the life, the symptom of headache, and have vexed, tinnitus, being irritable and getting angry easily, insomnia and dreamful sleep, hypomnesis, absent minded, forgetful situations such as (as: occurrence are not but remembered recently) takes place, present senile dementia, cerebral infarction, premorbid has the chronic insufficient cerebral blood supply premonitory symptom: remove headache, dizzy, outside the insomnias etc., it is obviously weak also to show whole body, feel sick, vomiting, fluctuation of blood pressure, the sleep of having dizzy spells; The numbness of hands and feet that has: numb tongue, lip fiber crops, fall or faint, sialorrhea, pronounce indistinctly; The involuntary twitch of limbs, nervus motorius functional failure etc., these all are the results that chronic insufficient cerebral blood supply causes.Theory with reference to modern Chinese medicine, and constantly groping in practice, and clinical verification in addition on the basis of secret prescription handed down in the family from generation to generation, put out the Chinese medicine prescription of following treatment cerebral blood supply insufficiency in order, it is to buy the finished product natural Chinese medicine that pharmaceuticals concocts that its medicine is formed, and comprising: prescriptions such as Stigma Croci, Os Draconis, Carapax Trionycis, Fructus Forsythiae, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, Herba Asari, Radix Angelicae Sinensis, Periostracum Serpentis, Pyritum, Ramulus Cinnamomi, Radix Angelicae Pubescentis, Scolopendra, Rhizoma Et Radix Notopterygii.
Go into selected Stigma Croci in the prescription: sweet, the little hardship of nature and flavor, cool in nature.Has thin channels and activating collaterals, stimulating the menstrual flow silt, diffusing silt relieving accumulation of pathogens, reducing swelling and alleviating pain, removing pathogenic heat from blood and toxic substance from the body, troubled thoughts pent-up, diseases such as extensive use is with prevention and treatment cerebral thrombosis, and vasculitis, myocardial infarction, anemia body void, menoxenia, puerperal congestion, general aching, traumatic injury, neurasthenia, palpitation with fear is demented.Adhere to for a long time taking and to receive and make us heart happiness, improve the effect of the immunity of human body comprehensively, scientific research shows, it is to improving aspect determined curative effects such as blood supply of cardiac muscle oxygen supply, and Stigma Croci contains the composition of multiple glycoside, and multiple glycoside can obviously increase big blood flow coronarius.
Os Draconis: nature and flavor are sweet, puckery, are slightly cold.GUIXIN, liver, kidney channel.Have tranquillizing the mind by relieving convulsion, suppressing the hyperactive liver and subsiding YANG is restrained astringent or styptic treatment for spontaneous sweating function.Be used for palpitation and insomnia, the vertigo etc. more;
Carapax Trionycis: property is little salty, is slightly cold, and returns liver, kidney channel, has nourishing YIN for suppressing the hyperactive YANG, and hard masses softening and resolving is brought down a fever and removed the function of steaming;
Fructus Forsythiae: have antibiotic, heart tonifying, diuresis, town pharmacological action, diseases such as the acute anemopyretic cold of forsythia fruit for treating commonly used, carbuncle sore tumefacting virus, tuberculous lymphadenitis, urinary tract infection such as to tell;
Pericarpium Citri Reticulatae: the little hardship of property, suffering, temperature.Return lung, spleen channel.Have regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm is used for stagnation of QI in spleen and stomach more, fullness in the epigastrium and chest or vomiting;
Herba Asari: warm in nature, acrid in the mouth, function has calmness, antipyretic effect and relievings asthma, eliminates the phlegm, antiinflammatory, immunosuppressant and antiallergic action, the metabolic function of raising body, heart tonifying, the blood pressure effect that resists myocardial ischemia, raises, antibiotic, antivirus action; Cure mainly diseases such as headche due to wind-cold, phlegm retention cough with asthma, rheumatic arthralgia, toothache, nasal sinusitis;
Radix Angelicae Sinensis: nature and flavor are sweet, hot, and temperature is returned liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, and the function of loosening bowel to relieve constipation is used for blood deficiency and yellow complexion, dizzy cardiopalmus etc.;
Periostracum Serpentis: property is little salty, and is sweet, flat, returns Liver Channel.Have and dispel the wind, calm the frightened, detoxify, the function of nebula removing;
Pyritum: nature and flavor suffering, flat, return Liver Channel.Have dissipating blood stasis, synthetism, analgesic function.The many externals of Pyritum also are used for wind syndrome of head pain etc.;
Cortex Magnoliae Officinalis: nature and flavor hardship, suffering, temperature is returned taste, lung, large intestine channel.Have the dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is removed full function;
Ramulus Cinnamomi: nature and flavor suffering, sweet, temperature, GUIXIN, lung, urinary bladder channel.Tool diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas effect of spining;
Radix Angelicae Pubescentis: nature and flavor suffering, hardship, tepor, return kidney, urinary bladder channel.Has expelling wind and removing dampness, logical spleen pain relieving, the function of inducing sweat.Be used for anemofrigid-damp arthralgia, lumbocrural pain, few sun volt phoenix headache wind and cold table disease, and lumbago and skelalgia, two failure of the lower limbs to walk such as walk at disease;
Scolopendra: nature and flavor suffering, temperature, poisonous, return Liver Channel.Has endogenous wind stopping spasmolytic, the function that dispersing pathogen accumulation, collateral dredging relieve the pain etc.;
Rhizoma Et Radix Notopterygii: property suffering, hardship, temperature is returned bladder, kidney channel.Have cold expelling, dispel the wind, dehumidifying, pain relieving; Be used for the anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back;
The composition and the weight portion proportioning of treatment cerebral blood supply insufficiency Chinese medicine preparation raw material of the present invention are:
Figure GSB00000522182800031
Chinese medicine preparation of the present invention by the composition and the weight portion proportioning of following optimum feed stock is:
Figure GSB00000522182800032
A kind of Chinese medicine preparation for the treatment of cerebral blood supply insufficiency adopts following unguentum technology:
1, preparation is preceding in strict accordance with its every the decoction pieces amount of dosetest of filling a prescription, and checks the quality of its raw material.
2, the decoction pieces of this preparation is crossed fry system, and successively put in poison, belong to hard sheet as Os Draconis, Pyritum and Carapax Trionycis, put in poison earlier, and as back prescribe medicines such as Herba Asari, Radix Angelicae Sinensis, Stigma Croci and Fructus Forsythiaes, according to above-mentioned ratio of weight and number material medicine, the Oleum sesami of every pair of preparation use and the ratio of Plumbum preparatium are 2: 1, that is use 4 kilograms of Oleum sesami, 2 kilograms of Plumbum preparatium.
3, make to decoct medicinal herbs on slow fire and seethe with excitement until the preparation oil cauldron, and anhydrous back prescribe medicine in the assurance oil cauldron, re-using slow fire behind the prescribe medicine boiled medicine 30 minutes, after extracting and filtering out the residue of decoction pieces, continuing to use under slow fire and the ebullient situation of messenger drug oil, following Plumbum preparatium, and stirred 20~30 minutes, become the weak coffee color and take the dish out of the pot at once, the cooling back becomes the preparation creme.
4, the preparation material is pasted by every dose 15 gram one, and be packaged into unguentum according to novel process.
Above-mentioned prescription is made unguentum according to novel process, according to different pathological manifestations and treatment stage, adopts Different Acupoint, different dosages to paste, and harmless to patient's blood circulation, and with health role to liver and gall stomach kidney.
The present invention is utilization modern medicine technology and inspection method, and with the blood stasis dispelling starting, filling blood is the basis, and the course of treatment in each week changes dressings twice, and concrete clinical treatment data statistics is as follows:
Figure GSB00000522182800041
Typical clinical is cured an example and is summarized as follows:
Case: Lee 72 years old, the cadre of Jilin Provincial Party committee, headache and insomnia, whole body are obviously weak, and how tame hospital all is diagnosed as cerebral blood supply insufficiency, and continues more than 30 year, and in JIUYUE, 2008, with taking effect in one week of this pharmaceutical formulation, three weeks fully recovered, and it is normal to appear the body situation;
Woman Zhao, 55 years old, the workman of this city electric bulbs factory, the front three hospital diagnosis is a cerebral blood supply insufficiency before more than 20 year, from the beginning arrives waist and numbness of hands and feet, dizziness headache, malaise, be in hospital twice invalid.In JIUYUE, 2008 tentatively took effect with this medicine in three days, and three all effects are obvious, now fully recovered, and life is normal;
Lee economizes the vehicle repairing factory cadre, headache and dizzy over more than 10 year, and malaise is a cerebral blood supply insufficiency through local hospital diagnosis, and several times large hospital is failed to respond to any medical treatment, and fully recover with two weeks of this pharmaceutical formulation in March, 2009;
Woman Hao, 40 years old, the cadre of Jilin Provincial Party committee, cerebral blood supply insufficiency, headache and insomnia influences work, and 4 day tentatively take effect with this pharmaceutical formulation in April, 2009, the recovery from illness of five weeks;
Wang 57 years old, cerebral blood supply insufficiency reaches 20 years, fails to respond to any medical treatment through various big hospital, with tentatively taking effect the recovery from illness of three weeks in one week of this pharmaceutical formulation.
According to adding up clinically, 2/3 people suffers from chronic insufficient cerebral blood supply in the mid-aged population, it is the stealthy killer of healthy elder that primary disease is called, the inventor's relatives, before more than 30 year because wound after, suffers from comprehensive cerebral blood supply insufficiency disease, last lower limb are malfunctioning, and many diseases are burdened with, and use this pharmaceutical formulation, make it obtain new life, go to 78 years old of today healthyly.
The invention has the advantages that: as can be seen by above-mentioned case, the Chinese medicine preparation of this treatment cerebral blood supply insufficiency has the conspicuous therapeutic effect to the patient, and uses this preparation that the patient is not produced any side effect, treatment time is short, instant effect, expense is low, and needn't arrive hospital's hospitalization, do not influence work, do not influence family life and normal comings and goings, have excellent popularization, have very significant effect improving and promote patient's body health.
The specific embodiment
Embodiment 1
The present invention treats the cerebral blood supply insufficiency Chinese medicine preparation:
The preparation decoction pieces (actual gross weight is 1160 kilograms) of above-mentioned total 232 weight portion proportionings is oily excessively, and successively put in poison, hard sheet belonged to as Os Draconis, Pyritum and Carapax Trionycis, put in poison earlier, and as back prescribe medicines such as Herba Asari, Radix Angelicae Sinensis, Stigma Croci and Fructus Forsythiaes, every pair of preparation uses 4 kilograms of Oleum sesami, 2 kilograms of Plumbum preparatium;
Making decocts medicinal herbs on slow fire seethes with excitement until the preparation oil cauldron, and can put in poison after anhydrous in the assurance oil cauldron, slow fire 30 minutes are continued to use in the prescribe medicine back, and must not make the decoction pieces blackening, extract and filter out the residue of decoction pieces after, make under the oily ebullient situation, following Plumbum preparatium, and stirred 20~30 minutes, becoming weak coffee color shape and take the dish out of the pot at once, the cooling back becomes the preparation creme;
The preparation creme is pasted by every dose 15 gram one, and be packaged into unguentum according to novel process.
Embodiment 2
The present invention treats the cerebral blood supply insufficiency Chinese medicine preparation:
Figure GSB00000522182800061
The preparation decoction pieces of above-mentioned 263 weight portion proportionings is made unguentum according to the method for making of embodiment 1.
Embodiment 3
Figure GSB00000522182800062
The preparation decoction pieces of above-mentioned 330 weight portion proportionings is made unguentum according to the method for making of embodiment 1.
Embodiment 4
The present invention treats the cerebral blood supply insufficiency Chinese medicine preparation and presses column weight amount portion rate material medicine and be:
Figure GSB00000522182800063
The preparation decoction pieces of above-mentioned 278 weight portion proportionings is made unguentum according to the method for making of embodiment 1.

Claims (2)

1. Chinese medicine unguentum for the treatment of cerebral blood supply insufficiency, it is characterized in that: composition and the weight portion proportioning thereof of making the various Chinese crude drugs of described Chinese medicine unguentum are:
Figure FSB00000522182700011
2. according to the described a kind of Chinese medicine unguentum for the treatment of cerebral blood supply insufficiency of claim 1, it is characterized in that: various Chinese crude drugs compositions and the ratio of weight and number thereof of making described Chinese medicine unguentum further are:
Figure FSB00000522182700012
CN2009100673388A 2009-07-24 2009-07-24 Traditional Chinese medicine preparation for treating cerebral circulation insufficiency Expired - Fee Related CN101607007B (en)

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CN111358879A (en) * 2020-04-10 2020-07-03 黑龙江中医药大学 Traditional Chinese medicine composition with kidney tonifying function for treating ischemic brain injury and preparation method thereof

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN1872214A (en) * 2005-06-03 2006-12-06 天津天士力制药股份有限公司 Application of medication composition of containing notoperygium root in preparing medication for treating chronic insufficiency of supplying blood for brain

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1872214A (en) * 2005-06-03 2006-12-06 天津天士力制药股份有限公司 Application of medication composition of containing notoperygium root in preparing medication for treating chronic insufficiency of supplying blood for brain

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘清华等.《中药内服外敷治疗颈性眩晕63例》.《光明中医》.2009,第24卷(第3期),475-476. *
第6卷.《中医治疗椎-基底动脉供血不足进展》.《中国中医药信息杂志》.1999,第6卷(第7期),17-18. *

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