CN103585319B - A kind ofly treat Chinese medicine composition of flaccidity caused by deficiency of both the liver and kidney and preparation method thereof - Google Patents
A kind ofly treat Chinese medicine composition of flaccidity caused by deficiency of both the liver and kidney and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition, especially relate to a kind of Chinese medicine composition for the treatment of flaccidity caused by deficiency of both the liver and kidney, take off the primary raw material stating weight proportion and be prepared from: geranium 10-30 part, Fructus Rosae Laevigatae 10-30 part, Celastrus orbiculatus Thunb. 10-30 part, Bionic tiger bone 10-20 part, Herba Cynomorii 10-20 part, Caulis Lonicerae 10-20 part, Folium Mahoniae 10-20 part, Herba Cistanches 10-20 part, Semen Cuscutae 10-20 part.Chinese medicine composition of the present invention proves there is good therapeutic effect to the amyotrophy that the flaccidity caused by deficiency of both the liver and kidney and a variety of causes cause by clinical treatment for many years, Chinese medicine composition of the present invention has replenishing QI to invigorate the spleen, the liver and the kidney tonifying, nourishing YIN and clearing away heat, blood circulation promoting and blood stasis dispelling, dredge the meridian passage, effect of strong muscles and bones, also has the advantage that Be very effective, drug effect are definite simultaneously.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to and a kind ofly treat Chinese medicine composition of flaccidity caused by deficiency of both the liver and kidney and preparation method thereof.
Background technology
Flaccidity is relaxed with limbs muscle arteries and veins, weakness, must not voluntary movement, with the passing of time causes amyotrophy or quadriplegia is the disease of feature.Cause the reason of flaccidity disease very complicated, being invaded by exogenous pathogen, feelings will internal injury, eating and drinking without temperance, overstrain prolonged illness etc. all can be caused a disease.Basic pathogenesis is that the internal organs vital essence such as lung stomach Liver and kidney are impaired, and limbs muscle arteries and veins loses supports, as lung-heat Tianjin wound, and body fluid not cloth; Damp and hot contamination, QI and blood is not transported; Taste virtual loss, precise and tiny not defeated; Deficiency of both the liver and kidney, the withered flaccidity due to malnutrition of tendons of marrow.Dialectically mainly distinguish deficiency and excess, specify disease position.Treat the suitable invigorating the spleen and benefiting QI of empty person, nourishing the liver and kidney, real person's clearing away heat and eliminating dampness, eliminates the phlegm and invigorates blood circulation.Pay attention to " person solely gets positive bright to control flaccidity ", medical treatment taste.Clinical differentiation lung-heat Tianjin wound, damp and hot contamination, taste virtual loss, deficiency of both the liver and kidney card are distinguished and are controlled.
Flaccidity refers to that limbs muscle slow pulse delays, and brothers' flaccidity is soft unable, with the passing of time because of can not voluntary movement and cause amyotrophic a kind of disease, with lower limb can not voluntary movement and walker comparatively common.Namely the traditional Chinese medical science had more deep understanding to " myopathy " before 2000.Huangdi's Internal Classics is established " myopathy " special section, to the etiology and pathogenesis of myopathy as the detailed description of comparatively system, propose the basic rule for the treatment of of viewpoint that " the scorehed lung-lobe due to lung-heat " is main pathogenesis and " treating flaccidity syndromes have to treat first YANG MING ", and the difference of internal organs is affected according to the cause of disease, be divided into five flaccidity such as vessel-flaccidity, muscular atrophy, the atrophic debility of bones, flaccidity due to malnutrition of tendons, skin arm, and think that myopathy is main dirty relevant with lung stomach Liver and kidney four.These basic principles are until still have important directive significance to clinical today.On this basis, ancient Chinese medicine doctor has done more detailed performance and perfect, makes myopathy on Clinics and Practices, define a more complete theoretical system of ratio.It is worthy of note, motherland's medical science, while theory is constantly perfect, has summed up large quantities of effective formula and drug and single proved recipe, have accumulated abundant practice data and effective experience for later age is studied and treats.
The flaccidity that the traditional Chinese medical science is discussed, be equivalent to the muscle disease that modern Western medicine is discussed clinically, comprise myasthenia gravis, duchenne muscular dystrophy, motor neuron disease, polymyositis and dermatomyositis, periodic paralysis, polyneuritis, syringomyelia, metabolic disease, hyperthyroid disease, tatanic disease etc.1672, British scholar Thomas Williks first described very easily tired and that after having a rest, symptom the alleviates myasthenia gravis typical case of skeletal muscle; 1868, to describe Clinical symptoms be first the unable of skeletal muscle and atrophy to Du Xing Shi, how by limbs near-end, and the typical case of the duchenne muscular dystrophy of progressive muscle weakness and atrophy in Zygomorphy.1865, Charot described the clinical manifestation and pathology finding etc. of motor neuron disease in detail.Other muscle disease is later also successively by some scholars are reported.
Modern medicine is relatively late to the understanding of assertive evidence.After the mankind are familiar with self immune system and nervimuscular Nutrition, modern medicine just has more complete discussion for the disease that myopathy is similar.And rope and the practice deeply further in treatment, in general can't be fully up to expectations, be almost at a loss what to do to some disease.But due to making rapid progress of modern science and technology, the development of modern medicine is also very fast, deepening constantly especially in etiology and pathology understanding, to the incidence of primary disease more specifically, brighter and clearer, this point is mathematical.
For macular disease, because doctor trained in Western medicine there is no specific medicament, and the traditional Chinese medical science have accumulated abundant clinical experience in the development of thousand, and after "Nei Jing", ancient Chinese medicine doctor has the discussion about myopathy, develops to some extent in the etiology and pathogenesis, dialectical treatment of myopathy.So general advocating uses Chinese medicine to carry out prevention and therapy at present.
Authorization Notice No. CN 1526440 A(application number 03157551.X) Chinese patent literature provide one and treat amyotrophy myasthenia---compound Chinese medicinal preparation and the method for preparing of flaccidity is characterized in that: its formula is by raw material 100% weighing scale RHIZONA GASTRODIAE 2.5-25%, Scorpio 5-25%, Scolopendra (removing foot) 1-15%, Pheretima 4-15%, Radix Achyranthis Bidentatae 1-10%, Radix Dipsaci 1-15%, charred Cortex Eucommiae 3-15%.If it is formulated by raw material 100% RHIZONA GASTRODIAE 2.3-30%, Scorpio 5-30%, Scolopendra (removing foot) 15-50% that patient's serious symptom adds its formula unable.Authorization Notice No. CN 102895481 A(application number 201110211763.7) Chinese patent literature provide a kind of medicine for the treatment of flaccidity, preferred scheme is crude drug formula and part by weight thereof is Radix Ginseng 15 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Cortex Phellodendri 12 parts, the Rhizoma Anemarrhenae 12 parts, Radix Achyranthis Bidentatae 20 parts, Radix Stephaniae Tetrandrae 20 parts, Rhizoma Atractylodis 16 parts, 15 parts, Semen Persicae, 15 parts, Flos Carthami, Radix Angelicae Sinensis 18 parts, Rhizoma Chuanxiong 15 parts, Radix Rehmanniae Preparata 25 parts, the Radix Paeoniae Alba 18 parts, castor Collettii 18 parts, Carapax et Plastrum Testudinis 20 parts and Herba Cynomorii 15 parts.
In a word, Chinese medicine achieves good curative effect in treatment primary disease, but also there are some problems: clinically there is replenishing QI to invigorate the spleen, the liver and the kidney tonifying, nourishing YIN and clearing away heat, blood circulation promoting and blood stasis dispelling, dredge the meridian passage, the medicine of effect of strong muscles and bones is not also very desirable, does not also have better formula to treatment flaccidity, especially in flaccidity caused by treatment deficiency of both the liver and kidney.
Summary of the invention
A kind of Chinese medicine composition for the treatment of flaccidity caused by deficiency of both the liver and kidney is the invention provides for above problem, this Chinese medicine composition proves there is good therapeutic effect to the amyotrophy that the flaccidity caused by deficiency of both the liver and kidney and a variety of causes cause by clinical treatment for many years, Chinese medicine composition replenishing QI to invigorate the spleen of the present invention, the liver and the kidney tonifying, nourishing YIN and clearing away heat, blood circulation promoting and blood stasis dispelling, dredge the meridian passage, effect of strong muscles and bones, has the advantage that Be very effective, drug effect are definite.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine composition for flaccidity caused by deficiency of both the liver and kidney, take off the primary raw material stating weight proportion and be prepared from: geranium 10-30 part, Fructus Rosae Laevigatae 10-30 part, Celastrus orbiculatus Thunb. 10-30 part, Bionic tiger bone 10-20 part, Herba Cynomorii 10-20 part, Caulis Lonicerae 10-20 part, Folium Mahoniae 10-20 part, Herba Cistanches 10-20 part and Semen Cuscutae 10-20 part.
A kind of Chinese medicine composition for the treatment of flaccidity caused by deficiency of both the liver and kidney, preferred scheme is, its preferred version takes off the primary raw material stating weight proportion to be prepared from: geranium 15-25 part, Fructus Rosae Laevigatae 15-25 part, Celastrus orbiculatus Thunb. 15-25 part, Bionic tiger bone 13-18 part, Herba Cynomorii 13-18 part, Caulis Lonicerae 13-18 part, Folium Mahoniae 13-18 part, Herba Cistanches 13-18 part and Semen Cuscutae 13-18 part.
A kind of Chinese medicine composition for the treatment of flaccidity caused by deficiency of both the liver and kidney, the scheme be more preferably is, its preferred plan takes off the primary raw material stating weight proportion to be prepared from: geranium 20 parts, Fructus Rosae Laevigatae 20 parts, Celastrus orbiculatus Thunb. 20 parts, Bionic tiger bone 15 parts, Herba Cynomorii 15 parts, Caulis Lonicerae 15 parts, Folium Mahoniae 15 parts, Herba Cistanches 15 parts and Semen Cuscutae 15 parts.
The preparation method of the Chinese medicine composition of the primary raw material of above-mentioned weight proportion, is characterized in that, step is as follows:
(1) Chinese liquor that Fructus Rosae Laevigatae, Herba Cynomorii, Lao Ye, Herba Cistanches and Semen Cuscutae put into 30-50 DEG C soaks 1-5 days, take out dry stand-by;
(2) gained crude drug in step (1) is ground into smalls, crosses 120-140 mesh sieve;
(3) warm water being 20-40 DEG C by geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae temperature soaks 2 hours, and water consumption is 2-5 times of geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae gross weight;
(4) step (3) gained mixed liquor is heated to boiling, continue after 1 hour filter, obtain filtrate 1, adding water in filtering residue be heated to boiling continue after 30 minutes filter, obtain filtrate 2, by gained filtrate 1 through be concentrated into original volume 1/2 concentrated solution;
(5) gained filtrate 2 in step (4) is loaded in bottle stand-by;
(6) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stir into thick paste; Thick paste is dried 1-2 hour, obtains drying object, dry at temperature is 70-90 DEG C;
(7) step (6) gains are measured according to 0.3-0.7g/ sheet, be pressed into circular or other forms of tablet dosage form according to the preparation for processing of Chinese medicine composition.
Above-mentioned preparation method, preferred scheme is: the Chinese liquor that step (1) puts into 35-45 DEG C (preferably 40 DEG C) soaks 2-4 days (preferably 3 days).
Above-mentioned preparation method, preferred scheme is: step (2) crosses 125-135 mesh sieve (preferred mistake 130 mesh sieve).
Above-mentioned preparation method, preferred scheme is: step (3) warm water that temperature is 25-35 DEG C soaks (preferably the warm water of 30 DEG C).
Above-mentioned preparation method, preferred scheme is: step (6) dries 1.3-1.8 hour (preferably 1.5 hours).
Above-mentioned preparation method, preferred scheme is: step (6) dry at temperature is 75-85 DEG C (preferably dry at temperature 80 DEG C).
Above-mentioned preparation method, preferred scheme is: the dosage form of step (7) Chinese medicine composition is 0.4-0.6g/ sheet (preferred dosage form is 0.5 g/ sheet).
Using method: for making the present invention reach optimum therapeuticing effect, takes after 1 hour during above-mentioned tablets after the meal, 3 times on the one, each 2-3 gram, and before sleep in evening, filtrate 2 put into after bathtub mixes with water and bath, 3-5 days once, put 20ml at every turn.
This Chinese medicine composition, to the flaccidity Be very effective caused by deficiency of both the liver and kidney, has relaxing muscles and tendons to promote blood circulation, the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, the feature of promoting blood circulation, removing blood stasis and relieving pain.
A kind of pharmacological effect for the treatment of each crude drug of the Chinese medicine composition of flaccidity caused by deficiency of both the liver and kidney of the present invention is:
Geranium: bitter, micro-pungent is flat.Return liver, kidney, large intestine channel.For diseases such as rheumatic arthralgia, numb limbs and tense tendons, articular instabilities, effectively alone, be decocted in water for oral dose or endure cream and use; As medicines such as compatibility Ramulus Cinnamomi, Radix Angelicae Sinensis, Flos Carthami, Radix Paeoniaes, the effects such as promoting blood circulation, dredging meridian and relieving pain can be strengthened.
Fructus Rosae Laevigatae: sour, sweet, puckery, flat.Return kidney, bladder, large intestine channel.Astringent therapy, controlling nocturnal emission with astringent drugs, antidiarrheal.Be applicable to the diseases such as spermatorrhea, seminal emission, the enuresis, frequent micturition, insufficiency of the spleen chronic diarrhea and women's leukorrhagia, uterine prolapse.During catching a cold or heating patient's inedibility.
Celastrus orbiculatus Thunb.: expelling wind and removing dampness; Inducing menstruation to relieve menalgia; Promoting blood circulation and detoxication.Main rheumatic arthritis; Numb limbs and tense tendons, paralysis; Headache; Toothache; Hernia; Dysmenorrhea; Amenorrhea; Infantile convulsion; Osteopatia sprain; Dysentery; Acute filthy disease; Herpes zoster.Skin infection furuncle and phyma; Herpes; Eczema; Traumatic injury; Snake bite and insect sting.
Bionic tiger bone: sweet, acrid, warm.Return liver, kidney channel.Dispelling wind and removing obstruction in the collateral, strengthening the tendons and bones.For rheumatic arthralgia, foot knees soreness.
Herba Cynomorii: Herba Cynomorii is the Herba indigoferae Pseudotinctoriae the most often used in the medical material of the kidney invigorating, it can suppressing the hyperactive liver the kidney invigorating, beneficial intensive culture blood, loosening bowel to relieve constipation, the infertility that causes for the treatment of insufficiency of vital energy and blood, also can strengthening the tendons and bones, supplement calcium.Very large benefit is had to function of human body; Strengthen immunologic function; Scavenging free radicals; Antiplatelet aggregation; There is the effect of saccharide 17-hydroxy-11-dehydrocorticosterone sample; Vitimin supplement and mineral.Up-to-date scientific experiments proves that Herba Cynomorii also has the effect of anti-cancer, antiviral, slow down aging.Be applicable to hypoimmunity, easy infection disease patient; Young and middle-aged hardworking cause and healthy overdraw person; The multiple patients with chronic diseases such as frequent micturition constipation, insomnia alopecia, asthma, the weak premature ejaculation of flaccidity.Impotence and premature ejaculation, the moon declines Sanguis Draxonis, the weak deficiency of YIN of gas, and large constipation is dry, frequent micturition, and hematuria is not to the utmost dripping, and fear of cold is feared cold, limbs pain, menoxenia, cold womb leukorrhagia, and men and women is infertile, insomnia forgetfulness, and alopecia is early white, gastric acid ulcer etc.
Caulis Lonicerae: sweet, cold.Attach to the lung and stomach meridians.Heat-clearing and toxic substances removing, dispelling wind dredging collateral.For epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle skin infection, beriberoid pyretic arthralgia, redness and swelling of joints burning pain.
Folium Mahoniae: there is the effectiveness such as clearind deficient heat, liver and kidney tonifying, wind-damp dispelling.Be mainly used in hectic fever due to deficiency of YIN, cough is spat blood, had a dizzy spell, soreness of the waist and knees, rheumatic arthralgia, vitiligo etc.
Herba Cistanches: sweet in the mouth, salty, warm in nature.Energy kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.
Semen Cuscutae: Gui Jing: abnormal smells from the patient is pungent, sweet, flat nontoxic.[function with cure mainly]: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity.The waist knee joint muscles and bones being applicable to deficiency of the liver and kindey is ached, the diseases such as legs and feet weakness, impotence and seminal emission, crazy talk, frequent micturition, dripping urination, dizziness and blurred vision, blurring of vision, Hiccough and deaf and women's leukorrhagia, habitual abortion.
The present invention is a kind of to be treated the Chinese medicine composition of flaccidity caused by deficiency of both the liver and kidney and meets the theory of the traditional Chinese medical science about dermatitis.For above-mentioned in a kind of defect for the treatment of in the Chinese medicine composition process of flaccidity caused by deficiency of both the liver and kidney, this product, on the basis of summing up forefathers' experience, goes through clinical research for many years, adopts natural Chinese medicines unique formula and technique to refine and forms.This product includes abundant plant biological active component, can directly act on affected part.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1:treat a Chinese medicine composition for flaccidity caused by deficiency of both the liver and kidney, get the raw materials ready (getting 10g for every part) by following weight parts: geranium 10 parts, Fructus Rosae Laevigatae 10 parts, Celastrus orbiculatus Thunb. 10 parts, Bionic tiger bone 10 parts, Herba Cynomorii 10 parts, Caulis Lonicerae 10 parts, Folium Mahoniae 10 parts, Herba Cistanches 10 parts, Semen Cuscutae 10 parts.
Treat a Chinese medicine composition for flaccidity caused by deficiency of both the liver and kidney, preparation process is as follows:
(1) Fructus Rosae Laevigatae, Herba Cynomorii, Lao Ye, Herba Cistanches and Semen Cuscutae put into 30 DEG C Chinese liquor soak 1 day, take out dry stand-by;
(2) gained crude drug in step (1) is ground into smalls, crosses 120 mesh sieves;
(3) warm water being 20 DEG C by geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae temperature soaks 2 hours, and water consumption is 2 times of geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae gross weight;
(4) step (3) gained mixed liquor is heated to boiling, continue after 1 hour filter, obtain filtrate 1, adding water in filtering residue be heated to boiling continue after 30 minutes filter, obtain filtrate 2, by gained filtrate 1 through be concentrated into original volume 1/2 concentrated solution;
(5) load in bottle by gained filtrate 2 in step (4), before sleep in evening, filtrate 2 put into after bathtub mixes with water and bath, 3-5 days once, put 20ml at every turn;
(6) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stir into thick paste; Thick paste is dried 1 hour, obtain drying object, dry at temperature is 70 DEG C;
(7) step (6) gains are measured according to 0.3g/ sheet, be pressed into circular or other forms of tablet dosage form according to the preparation for processing of Chinese medicine composition, take after 1 hour after the meal when taking, 3 times on the one, each 2-3 gram.
typical case one:zhao so-and-so, man, 23 years old, people from Harbin.Carry out my institute's consultation of doctors in hospital on July 3rd, 2010, the severity very of pain in the lumbar region is felt in patient's readme recently, also be reluctant conation, whole body does not have strength, do not feel like a meal, once sleep on roof night, after fleying, do not eat and do not get into bed, disease is cried in compassion, cause lower limb flaccidity weak unable, flaccidity is diagnosed as through my institute, fail to respond to any medical treatment with medicine and physical therapy etc., more than the moon, all diseases are as front, so just look for old docter of TCM to treat, inspection through old docter of TCM finds patient body Feng Jian, god knows normal, there is the symptom of deficiency of both the liver and kidney, extremities joint spinal column is normally sore, lower limb physiological reflex and pathologic reflex are not all drawn, two lower limb muscles have no becomes thin, but can not bend and stretch and stand, arteries and veins gas is not all right, control solely to get the bright method of sun.See old docter of TCM, take Chinese medicine composition of the present invention, and be equipped with Traditional Chinese medicine medicated bath.
Take embodiment 1 gained Chinese medicine composition, and with the use of Traditional Chinese medicine medicated bath of the present invention, after 10 days, patient feels that whole body has strength, the mental status has also improved, appetite has increased, and continues to take embodiment 1 gained Chinese medicine composition after 10 days, and malaise symptoms disappears substantially, take again the present invention's conduct in 10 days to consolidate, without recurrence after drug withdrawal.
embodiment 2:treat a Chinese medicine composition for flaccidity caused by deficiency of both the liver and kidney, get the raw materials ready (getting 20g for every part) by following weight parts: geranium 30 parts, Fructus Rosae Laevigatae 30 parts, Celastrus orbiculatus Thunb. 30 parts, Bionic tiger bone 20 parts, Herba Cynomorii 20 parts, Caulis Lonicerae 20 parts, Folium Mahoniae 20 parts, Herba Cistanches 20 parts, Semen Cuscutae 20 parts.
Treat a Chinese medicine composition for flaccidity caused by deficiency of both the liver and kidney, preparation process is as follows:
(1) Fructus Rosae Laevigatae, Herba Cynomorii, Lao Ye, Herba Cistanches and Semen Cuscutae put into 50 DEG C Chinese liquor soak 5 days, take out dry stand-by;
(2) gained crude drug in step (1) is ground into smalls, crosses 140 mesh sieves;
(3) warm water being 40 DEG C by geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae temperature soaks 2 hours, and water consumption is 5 times of geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae gross weight;
(4) step (3) gained mixed liquor is heated to boiling, continue after 1 hour filter, obtain filtrate 1, adding water in filtering residue be heated to boiling continue after 30 minutes filter, obtain filtrate 2, by gained filtrate 1 through be concentrated into original volume 1/2 concentrated solution;
(5) gained filtrate 2 in step (4) is loaded bottle, before sleep in evening, filtrate 2 put into after bathtub mixes with water and bath, 3-5 days once, put 20ml at every turn;
(6) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stir into thick paste; Thick paste is dried 2 hours, obtain drying object, dry at temperature is 90 DEG C;
(7) step (6) gains are measured according to 0.7g/ sheet, be pressed into circular or other forms of tablet dosage form according to the preparation for processing of Chinese medicine composition, take after 1 hour after the meal when taking, 3 times on the one, each 2-3 gram.
typical case two:journey, patient, female, 32 years old, in October, 2012 went to a doctor, and patient's readme occurs heating after suffering from cold before 6 days, is up to 38.5 DEG C, with malaise.After taking an antipyretic, body temperature is down to normally.Before 5 days, body temperature rises to 39 DEG C, and occurs that right side numb limbs and tense tendons is unable, develops rapidly to lower limb by upper limb, symptom gradually increases the weight of, and can not walk voluntarily, and occur dysuria, so arrive, county hospital is gone to a doctor, and give retention catheterization, antiinflammatory symptomatic treatment, symptom has no improvement.Because patient is irritated to some Western medicine, so doctor advised drinks Chinese medicine composition of the present invention.
Take embodiment 2 gained Chinese medicine composition 10 days, patient temperature recovers normal, and muscle power strengthens to some extent, numb limbs and tense tendons is unable makes moderate progress on right side, and patient sees effective, continues again to have taken 10 days, take embodiment 2 gained Chinese medicine composition after 20 days, the malaise symptoms of patient disappears substantially.
embodiment 3:treat a Chinese medicine composition for flaccidity caused by deficiency of both the liver and kidney, get the raw materials ready (getting 30g for every part) by following weight parts: geranium 15 parts, Fructus Rosae Laevigatae 15 parts, Celastrus orbiculatus Thunb. 15 parts, Bionic tiger bone 13 parts, Herba Cynomorii 13 parts, Caulis Lonicerae 13 parts, Folium Mahoniae 13 parts, Herba Cistanches 13 parts, Semen Cuscutae 13 parts.
Treat a Chinese medicine composition for flaccidity caused by deficiency of both the liver and kidney, preparation process is as follows:
(1) Fructus Rosae Laevigatae, Herba Cynomorii, Lao Ye, Herba Cistanches and Semen Cuscutae put into 35 DEG C Chinese liquor soak 2 days, take out dry stand-by;
(2) gained crude drug in step (1) is ground into smalls, crosses 125 mesh sieves;
(3) warm water being 25 DEG C by geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae temperature soaks 2 hours, and water consumption is 3 times of geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae gross weight;
(4) step (3) gained mixed liquor is heated to boiling, continue after 1 hour filter, obtain filtrate 1, adding water in filtering residue be heated to boiling continue after 30 minutes filter, obtain filtrate 2, by gained filtrate 1 through be concentrated into original volume 1/2 concentrated solution;
(5) load in bottle by gained filtrate 2 in step (4), before sleep in evening, filtrate 2 put into after bathtub mixes with water and bath, 3-5 days once, put 20ml at every turn;
(6) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stir into thick paste; Thick paste is dried 1.3 hours, obtain drying object, dry at temperature is 75 DEG C;
(7) step (6) gains are measured according to 0.4g/ sheet, be pressed into circular or other forms of tablet dosage form according to the preparation for processing of Chinese medicine composition, take after 1 hour after the meal when taking, 3 times on the one, each 2-3 gram.
typical case three:lu, patient, man, 52 years old, in December, 2012 is gone to a doctor, patient's readme was walked before 3 months bilateral lower limb sensory disturbance, bilateral lower limb before sleeping with evening of getting up morning have the sense that disappears, spinal column is aching and limp also with the symptom of anorexia, squat of a specified duration and suddenly one stood up to feel there is Venus at the moment, also dizziness and tinnitus often, son sees this just band patient comprehensive inspection of having gone large hospital to do, neurologic check muscular strength reduces, amyotrophy is diagnosed as flaccidity, doctor advised hospitalization, owing to considering that family no one looks after the reason of old man, can only go home to treat according to the way of doctor, from after hospital goes home just perform physical exercise, also specially ask masseur's massage, after one month, patient's sensation there is not improvement, have also appeared the symptom of slight heating, son sees this and has feared, Chinese medicine composition of the present invention is to treatment flaccidity effect very good to listen friend to say, just bought 5 courses for the treatment of to take to patient.
Take embodiment 3 gained Chinese medicinal tablet, and with the use of embodiment 3 gained Traditional Chinese medicine medicated bath 10 days, patient's bilateral lower limb sensory disturbance disappears to some extent, the symptom of pain in the lumbar region also alleviates to some extent, patient sees effective, continues again to have taken 30 days, takes embodiment 3 gained Chinese medicine composition after 30 days, the malaise symptoms of patient disappears substantially, without recurring after continuing again to have taken drug withdrawal in 10 days.
embodiment 4:treat a Chinese medicine composition for flaccidity caused by deficiency of both the liver and kidney, get the raw materials ready (getting 40g for every part) by following weight parts: geranium 25 parts, Fructus Rosae Laevigatae 25 parts, Celastrus orbiculatus Thunb. 25 parts, Bionic tiger bone 18 parts, Herba Cynomorii 18 parts, Caulis Lonicerae 18 parts, Folium Mahoniae 18 parts, Herba Cistanches 18 parts, Semen Cuscutae 18 parts.
Treat a Chinese medicine composition for flaccidity caused by deficiency of both the liver and kidney, preparation process is as follows:
(1) Fructus Rosae Laevigatae, Herba Cynomorii, Lao Ye, Herba Cistanches and Semen Cuscutae put into 45 DEG C Chinese liquor soak 4 days, take out dry stand-by;
(2) gained crude drug in step (1) is ground into smalls, crosses 135 mesh sieves;
(3) warm water being 35 DEG C by geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae temperature soaks 2 hours, and water consumption is 4 times of geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae gross weight;
(4) step (3) gained mixed liquor is heated to boiling, continue after 1 hour filter, obtain filtrate 1, adding water in filtering residue be heated to boiling continue after 30 minutes filter, obtain filtrate 2, by gained filtrate 1 through be concentrated into original volume 1/2 concentrated solution;
(5) load in bottle by gained filtrate 2 in step (4), before sleep in evening, filtrate 2 put into after bathtub mixes with water and bath, 3-5 days once, put 20ml at every turn;
(6) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stir into thick paste; Thick paste is dried 1.8 hours, obtain drying object, dry at temperature is 85 DEG C;
(7) by step (6) gains according to 0.6/ metering, be pressed into circular or other forms of tablet dosage form according to the preparation for processing of Chinese medicine composition, take after 1 hour after the meal when taking, 3 times on the one, each 2-3 gram.
typical case four:tang XX, patient, man, 35 years old, Jinan, Shandong Province people, the workman of certain factory, in JIUYUE, 2011 is gone to a doctor, patient's readme a few months ago gradual limb adynamia continue for the time of one week, in this week age, aggravation 1 day, self-induction is in bad order, be convenient in JIUYUE, 2011 and accept treatment in hospital, old docter of TCM is when inquiring and ask, patient says that health one is not fine, easy infected wind and cold, back ache, see that patient has a dull expression on one's face, eyes are without god, complexion is turned to be yellow, old docter of TCM is defined as the flaccidity caused by deficiency of both the liver and kidney, Chinese medicine composition of the present invention is taken in old docter of TCM's suggestion, this Chinese medicine composition is to treatment flaccidity effect very good, so patient has just bought 3 courses for the treatment of and has taken.
Take embodiment 4 gained Chinese medicinal tablet, and with the use of embodiment 4 gained Traditional Chinese medicine medicated bath 10 days, patient's bilateral lower limb feel there is strength, and the symptom of pain in the lumbar region also alleviates to some extent, and patient sees effective, continue again to have taken 10 days, the malaise symptoms of patient disappears substantially, of pink and healthy-looking, goes to hospital to do further consultation, doctor says and is continuing to have taken 20 days, without recurrence after drug withdrawal.
embodiment 5:treat a Chinese medicine composition for flaccidity caused by deficiency of both the liver and kidney, get the raw materials ready (getting 50g for every part) by following weight parts: geranium 20 parts, Fructus Rosae Laevigatae 20 parts, Celastrus orbiculatus Thunb. 20 parts, Bionic tiger bone 15 parts, Herba Cynomorii 15 parts, Caulis Lonicerae 15 parts, Folium Mahoniae 15 parts, Herba Cistanches 15 parts, Semen Cuscutae 15 parts.
Treat a Chinese medicine composition for flaccidity caused by deficiency of both the liver and kidney, preparation process is as follows:
(1) Fructus Rosae Laevigatae, Herba Cynomorii, Lao Ye, Herba Cistanches and Semen Cuscutae put into 40 DEG C Chinese liquor soak 3 days, take out dry stand-by;
(2) gained crude drug in step (1) is ground into smalls, crosses 130 mesh sieves;
(3) warm water being 35 DEG C by geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae temperature soaks 2 hours, and water consumption is 3.5 times of geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae gross weight;
(4) step (3) gained mixed liquor is heated to boiling, continue after 1 hour filter, obtain filtrate 1, adding water in filtering residue be heated to boiling continue after 30 minutes filter, obtain filtrate 2, by gained filtrate 1 through be concentrated into original volume 1/2 concentrated solution;
(5) gained filtrate 2 in step (4) is loaded in bottle stand-by;
(6) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stir into thick paste; Thick paste is dried 1.5 hours, obtain drying object, dry at temperature is 80 DEG C;
(7) step (6) gains are measured according to 0.5g/ sheet, be pressed into circular or other forms of tablet dosage form according to the preparation for processing of Chinese medicine composition.
test examplethe clinical practice of Chinese medicine composition of flaccidity caused by embodiment 5 gained treatment deficiency of both the liver and kidney: in June, 2008 in December ,-2013, screen 120 routine patients in 4 hospitals, wherein women 58 example, male 62 example, oldest 72 years old, minimal ages 18 years old, 60 years old mean age.Before test 2 weeks, carry out Continuous Observation to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group takes embodiment 5 products obtained therefrom, and matched group takes other medicine.Using method is: take after 1 hour after the meal during tablets, 3 times on the one, each 2-3 gram, filtrate 2 is put into after bathtub mixes with water and baths, and bubble before sleep in evening, within 3-5 days, once, put into 20ml, 10 days be a course for the treatment of at every turn.Curative effect situation criterion: cure: malaise symptoms disappears, energy and muscle power obviously strengthen; Effective: malaise symptoms alleviates or partial disappearance, energy and muscle power strengthen; Invalid: malaise symptoms is unchanged.Result is as shown in table 1.
Table 1: take flaccidity patient treatment outcome caused by embodiment 5 product 18-72 year deficiency of both the liver and kidney
Therapeutic effect: cure 72 examples (72%), effective 27 examples (27%), invalid 1 example (1%), total effective rate 99%.Successful is better than matched group.
During taking, self-induction symptom and lower limbs strength thereof change as shown in table 2.
Table 2:
Take 30 days, more than 72% feel takes a turn for the better to some extent, and malaise symptoms improves or disappears, and the aching and limp symptom of spinal column alleviates; Take 30 days, more than 97% feel takes a turn for the better to some extent, and malaise symptoms improves or disappears, and the aching and limp symptom of spinal column alleviates, and lower limbs strength strengthens, and amyotrophic symptom also has good improvement, and some patients self-induction is fully recovered.Take more than 30 days in experimental group, effective percentage can reach 93%, and matched group is only 76%.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (8)
1. treat a preparation method for the Chinese medicine composition of flaccidity caused by deficiency of both the liver and kidney, it is characterized in that: take off the raw material stating weight proportion: geranium 10-30 part, Fructus Rosae Laevigatae 10-30 part, Celastrus orbiculatus Thunb. 10-30 part, Bionic tiger bone 10-20 part, Herba Cynomorii 10-20 part, Caulis Lonicerae 10-20 part, Folium Mahoniae 10-20 part, Herba Cistanches 10-20 part and Semen Cuscutae 10-20 part;
Step is as follows:
(1) Chinese liquor Fructus Rosae Laevigatae, Herba Cynomorii, Folium Mahoniae, Herba Cistanches and Semen Cuscutae being put into 35-45 DEG C soaks 2-4 days, and taking-up is dried stand-by;
(2) gained crude drug in step (1) is ground into smalls, crosses 125-135 mesh sieve;
(3) warm water being 25-35 DEG C by geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae temperature soaks 2 hours, and water consumption is 2-5 times of geranium, Celastrus orbiculatus Thunb., Bionic tiger bone and Caulis Lonicerae gross weight;
(4) step (3) gained mixed liquor is heated to boiling, continues to filter after 1 hour, obtain filtrate 1, adding water in filtering residue is heated to seethe with excitement continues to filter after 30 minutes, obtaining filtrate 2, by gained filtrate 1 through being concentrated into 1/2 of original volume, obtaining concentrated solution;
(5) load in bottle by gained filtrate 2 in step (4), before sleep in evening, filtrate 2 put into after bathtub mixes with water and bath, 3-5 days once, put 20ml at every turn;
(6) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stir into thick paste; Thick paste is dried 1.3-1.8 hour, obtains drying object, dry at temperature is 75-85 DEG C;
(7) step (6) gains are measured according to 0.4-0.6g/ sheet, be pressed into circular or other forms of tablet dosage form according to the preparation for processing of Chinese medicine composition.
2. preparation method according to claim 1, is characterized in that: take off the raw material stating weight proportion: geranium 15-25 part, Fructus Rosae Laevigatae 15-25 part, Celastrus orbiculatus Thunb. 15-25 part, Bionic tiger bone 13-18 part, Herba Cynomorii 13-18 part, Caulis Lonicerae 13-18 part, Folium Mahoniae 13-18 part, Herba Cistanches 13-18 part and Semen Cuscutae 13-18 part.
3. preparation method according to claim 1, is characterized in that: take off the raw material stating weight proportion: geranium 20 parts, Fructus Rosae Laevigatae 20 parts, Celastrus orbiculatus Thunb. 20 parts, Bionic tiger bone 15 parts, Herba Cynomorii 15 parts, Caulis Lonicerae 15 parts, Folium Mahoniae 15 parts, Herba Cistanches 15 parts and Semen Cuscutae 15 parts.
4. preparation method according to claim 1, is characterized in that: step (2) crosses 130 mesh sieves.
5. preparation method according to claim 1, is characterized in that: step (3) warm water that temperature is 30 DEG C is soaked.
6. preparation method according to claim 1, is characterized in that: step (6) is dried 1.5 hours.
7. preparation method according to claim 1, is characterized in that: step (6) is dry at temperature 80 DEG C.
8. preparation method according to claim 1, is characterized in that: the dosage form of step (7) Chinese medicine composition is 0.5 g/ sheet.
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|---|---|---|---|---|
| CN1895403A (en) * | 2006-06-14 | 2007-01-17 | 张国清 | Compound Chinese medicine for treating bone stitch and its preparation |
| CN102579708A (en) * | 2012-03-15 | 2012-07-18 | 黄方柱 | Chinese medicinal formula for tonifying yang and reinforcing kidney, liver and lung |
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| CN103585319A (en) | 2014-02-19 |
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