CN105381441A - Traditional Chinese medicine capsule for preventing and treating cyesedema and preparation method of traditional Chinese medicine capsule - Google Patents
Traditional Chinese medicine capsule for preventing and treating cyesedema and preparation method of traditional Chinese medicine capsule Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine capsule for preventing and treating cyesedema and a preparation method of the traditional Chinese medicine capsule, belonging to the field of traditional Chinese medicines. The traditional Chinese medicine in the capsule is prepared from the following active ingredients in parts by weight: 15-30 parts of Chinese yam, 15-30 parts of rhizoma smilacis glabrae, 15-30 parts of ramulus mori, 15-30 parts of liriope spicata, 5-15 parts of rhizoma zingiberis, 5-15 parts of white atractylodes rhizome, 5-15 parts of rhizoma alismatis, 5-15 parts of teasel root, 5-15 parts of radix angelica sinensis, 5-15 parts of chingma abutilon seeds, 5-15 parts of ginseng, 3-10 parts of rhizoma chuanxiong, 3-10 parts of cortex acanthopanacis, 3-10 parts of radix paeoniae rubra, 3-10 parts of fourstamen stephania root, 3-10 parts of radix scutellariae, and 3-10 parts of the shell of areca nut. The traditional Chinese medicine adopts the formula aiming at cyesedema which is caused by spleen-deficiency syndrome, deficiency of kidney-yang, heart and lung compelled by water, qi and water stagnation, and cold-dampness syndrome, has the efficacies of nourishing blood and clearing heat, resolving dampness and eliminating swelling, warming the kidney and inducing diuresis, tonifying the spleen and preventing miscarriage, regulating qi-flowing for activating stagnancy, as well as dispelling coldness and eliminating moisture, is free of untoward effects to the parent, the embryo and the fetus, free of the teratogenesis phenomenon, good in absorption effect, and high in cure rate, and is suitable for popularization and application clinically.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine capsules for preventing and treating edema during pregnancy and preparation method, select medical material to meet a monarch and his subjects left side and make it reason, compel cardiopulmonary type for insufficiency of the spleen pattern of syndrome, kidney yang deficiency syndrome, water, edema during pregnancy that stagnation of QI water retention type, cold-damp pattern of syndrome cause, there is heat clearing away of nourishing blood, removing dampness detumescence, warming the kidney to promote diuresis, spleen invigorating be antiabortive, regulating qi-flowing for activating stagnancy, cold expelling dry, effect of activating YANG for promoting diuresis.
Background technology
After edema during pregnancy refers to gestation, there is edema in the positions such as limbs appearance, claims " edema during pregnancy ", also known as " edema and distension during pregnancy ".Change mainly due to anemia of pregnant woman's endocrine, cause moisture and salt retention (sodium retention) in in-vivo tissue; In addition, the vein of gravid uterus compressing pelvic cavity and lower limb, hinders blood backflow, venous pressure is increased, therefore edema often occurs in limb far-end, based on foot and shank.
Doctor trained in Western medicine clinical diagnosis is, edema during pregnancy is mainly divided into:
(1) physiological edema, mainly because uterus compressing causes, the uterus of increase can be oppressed from heart through the blood vessel of pelvis to both legs.Blood and lymph fluid circulation are not smooth, metabolism is bad, leg tissue body fluid is caused to deposit, generally mostly occur and to locate below ankle or knee, usual anemia of pregnant woman in the morning WA does not have manifest symptom, but stand for a long time through daytime and nocturnalism amount reduce after, approximately at night sleep before, edematous condition will be obvious.And in the different time of a day, the position of edema is different, if foot is raised 1 hour, the edema of leg and ankle can alleviate, its blood pressure is within normal range, and producing urine detection when examining does not have urine protein, because physiological edema roughly can not cause harmful effect to fetus, and this edema meeting in puerperal spontaneous recovery, so ready-to-be mother is without excessive worry;
(2) how pathosis edema, caused by disease, such as the disease etc. of pregnancy induced hypertension syndrome, nephropathy, heart disease or other liver aspects, and these diseases not only can cause impact in various degree to the health of ready-to-be mother, also have harm to the health of fetus.And the symptom of pathosis edema is not only presented on lower extremity, both hands, face, abdominal part etc. all likely occurs.If when pressing skin with have gentle hands, skin reaction is many can present sagging, there is no the phenomenon such as elasticity, colour of skin dark blue.If what ready-to-be mother met with is pathologic edema, need to seek medical advice in time, seek doctor and help treatment.Because edema may cause nerve compression, sometimes then can cause that large leg outer side is numb, finger tip twinge, or sensory deprivation.
The exception that edema can show as body weight at first increases (i.e. latent edema), weekly more than 0.5kg, or occurs pitting edema, namely the clinical visible edema that in body, hydrops too much causes, many by ankle, gradually prolong to shank, thigh, external genital, abdominal part, the depression of pressing.Edema is divided into level Four, represents with "+"."+" edema is confined to ankle and shank; " ++ " edema is prolonged and thigh; " +++ " edema is prolonged and pudendum and abdominal part; " ++++" hydrosarca or companion's ascites.
Traditional Chinese medical theory is thought: edema during pregnancy mainly contains insufficiency of the spleen pattern of syndrome, kidney yang deficiency syndrome, water compel cardiopulmonary type, stagnation of QI water retention type, cold-damp pattern of syndrome edema during pregnancy etc.Clinical manifestation is:
(1) the gestation several months, appearance extremity edema or throughout whole body, companion's sensation of oppression over the chest with shortness of breath, tastelessness, inappetence, large loose stool are thin, and body of the tongue is fat tender, and there is indentation on white and thin fur or greasy, limit, and moderate pulse is sliding unable;
(2) the gestation several months, puffiness of the face and limbs, especially being very below waist, extremities being not warm, weakness of the waist and knees, there is indentation on pale tongue or limit, white and moist fur, deep-slow pulse;
(3) the gestation several months, limb swelling, begin swollen two foots, and gradually and in lower limb, color of the leather is constant, and impression does not show, dizzy distending pain, fullness and distention in the chest and hypochondrium, and Yin decreased food intake is few, greasy and thin fur, stringy and rolling pulse.
At present, edema during pregnancy disease for various pattern of syndrome mainly adopts treatment by Chinese herbs, there is the Chinese medicine of some treatment edema during pregnancy on the market, all mostly the Chinese medicine of the edema during pregnancy disease of exclusive certain pattern of syndrome for the treatment of, can not the treatment by Chinese herbs means of the comprehensive multiple pattern of syndrome edema during pregnancy caused for Different types of etiopathogenises.
For addressing the aforementioned drawbacks, Chinese medicine preparation of the present invention, compel cardiopulmonary type for insufficiency of the spleen pattern of syndrome, kidney yang deficiency syndrome, water, edema during pregnancy that stagnation of QI water retention type, cold-damp pattern of syndrome cause, there is heat clearing away of nourishing blood, removing dampness detumescence, warming the kidney to promote diuresis, spleen invigorating be antiabortive, regulating qi-flowing for activating stagnancy, cold expelling dry, effect of activating YANG for promoting diuresis.Have no adverse reaction to parent, embryo, fetus through clinical verification medicine of the present invention, do not occur teratogenesis phenomenon, assimilation effect is better, and be convenient for carrying, cure rate is up to 90%.
Summary of the invention
The invention provides a kind of Chinese medicine capsules for preventing and treating edema during pregnancy and preparation method, the present invention selects medical material to meet a monarch and his subjects left side and makes it reason, compel cardiopulmonary type for insufficiency of the spleen pattern of syndrome, kidney yang deficiency syndrome, water, edema during pregnancy that stagnation of QI water retention type, cold-damp pattern of syndrome cause, there is heat clearing away of nourishing blood, removing dampness detumescence, warming the kidney to promote diuresis, spleen invigorating is antiabortive, regulating qi-flowing for activating stagnancy, cold expelling dry, effect of activating YANG for promoting diuresis, through clinical verification medicine of the present invention, parent, embryo, fetus are had no adverse reaction, there is not teratogenesis phenomenon, assimilation effect is better, and cure rate is up to 90%.
For achieving the above object, technical scheme of the present invention is implemented as follows:
For preventing and treating Chinese medicine capsules and the preparation method of edema during pregnancy, raw material composition and the parts by weight of making described Effective Component of Chinese Medicine are:
Rhizoma Dioscoreae 15g ~ 30g Rhizoma Smilacis Glabrae 15g ~ 30g Ramulus Mori 15g ~ 30g soil 15g ~ 30g Radix Ophiopogonis
Rhizoma Zingiberis 5g ~ 15g Rhizoma Atractylodis Macrocephalae 5g ~ 15g Rhizoma Alismatis 5g ~ 15g Radix Dipsaci 5g ~ 15g Radix Angelicae Sinensis 5g ~ 15g
Semen Abutili 5g ~ 15g Radix Ginseng 5g ~ 15g Rhizoma Chuanxiong 3g ~ 10g Cortex Acanthopancis 3g ~ 10g
Radix Paeoniae Rubra 3g ~ 10g Radix Stephaniae Tetrandrae 3g ~ 10g Radix Scutellariae 3g ~ 10g Pericarpium Arecae 3g ~ 10g.
Raw material composition and the parts by weight of making described Effective Component of Chinese Medicine are:
Rhizoma Dioscoreae 19g ~ 26g Rhizoma Smilacis Glabrae 19g ~ 26g Ramulus Mori 19g ~ 26g soil 19g ~ 26g Radix Ophiopogonis
Rhizoma Zingiberis 8g ~ 12g Rhizoma Atractylodis Macrocephalae 8g ~ 12g Rhizoma Alismatis 8g ~ 12g Radix Dipsaci 8g ~ 12g Radix Angelicae Sinensis 8g ~ 12g
Semen Abutili 8g ~ 12g Radix Ginseng 8g ~ 12g Rhizoma Chuanxiong 4g ~ 7g Cortex Acanthopancis 4g ~ 7g
Radix Paeoniae Rubra 4g ~ 7g Radix Stephaniae Tetrandrae 4g ~ 7g Radix Scutellariae 4g ~ 7g Pericarpium Arecae 4g ~ 7g.
Raw material composition and the parts by weight of making described Effective Component of Chinese Medicine are:
Rhizoma Dioscoreae 25g Rhizoma Smilacis Glabrae 25g Ramulus Mori 25g soil 25g Radix Ophiopogonis
Rhizoma Zingiberis 10g Rhizoma Atractylodis Macrocephalae 10g Rhizoma Alismatis 10g Radix Dipsaci 10g Radix Angelicae Sinensis 10g
Semen Abutili 10g Radix Ginseng 10g Rhizoma Chuanxiong 5g Cortex Acanthopancis 5g
Radix Paeoniae Rubra 5g Radix Stephaniae Tetrandrae 5g Radix Scutellariae 5g Pericarpium Arecae 5g.
For preventing and treating a preparation method for the Chinese medicine capsules of edema during pregnancy, comprise following processing step:
1) first wheat bran is sprinkled in hot pot, when time cigarette is emerged, Rhizoma Dioscoreae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Alismatis is poured respectively into micro-stir-fry to surface in faint yellow, taking-up, sieve after removing wheat bran and cool, be ground into powder, cross 80 mesh sieves, for subsequent use;
(2) Rhizoma Smilacis Glabrae, Ramulus Mori, native Radix Ophiopogonis, Rhizoma Zingiberis, Semen Abutili, Radix Ginseng, Radix Stephaniae Tetrandrae, Pericarpium Arecae are picked decontamination respectively, be ground into powder, cross 80 mesh sieves, for subsequent use;
(3) Radix Angelicae Sinensis, Rhizoma Chuanxiong, Cortex Acanthopancis, Radix Scutellariae are picked decontamination respectively, clean, section is dried, and gets Radix Angelicae Sinensis Tabellae, Rhizoma Chuanxiong sheet, Cortex Acanthopancis, scutellaria tablet spray shao-hsing rice wine respectively (be 10:1 with shao-hsing rice wine proportion by subtraction), mix thoroughly, extremely surperficial in micro-yellow with the micro-stir-fry of slow fire, take out, cool, be ground into powder, cross 80 mesh sieves, for subsequent use;
(4) Radix Dipsaci, Radix Paeoniae Rubra are gone to pick decontamination respectively, section after cleaning, dry, get Radix Dipsaci sheet, Radix Paeoniae Rubra sheet enters respectively in pot and fry to surperficial micro-Jiao with slow fire, take out, cool, be ground into powder, cross 80 mesh sieves, for subsequent use;
(5) by the powder of step 1, step 2, step 3, step 4 gained, to pour in container mixing into and mix thoroughly, the water adding 9 times amount of dose carries out decoctions to after seething with excitement, continue, with slow fire boiling 40 minutes, to leach medicinal liquid, by the thick paste of relative density 1.20 under the concentration of liquid medicine of filtering most 75 DEG C of environment, carry out cold drying, pulverize, add appropriate dextrin, mixing, granulate, cold drying, granulate, incapsulate, to obtain final product.
The property of medicine of the present invention's Chinese medicine used is as follows:
Rhizoma Dioscoreae: sweet in the mouth; Property is put down.Enter lung; Spleen; Kidney channel.Spleen reinforcing; Support lung; Reinforce the kidney; Benefit essence.Cure mainly diarrhea due to hypofunction of the spleen; Lack of appetite edema; Cough and asthma due to lung deficiency; Quench one's thirst; Seminal emission; Leukorrhagia; To suffer from a deficiency of the kidney frequent micturition; Carbuncle is controlled in external; Scrofula." book on Chinese herbal medicine just " carries: " Rhizoma Dioscoreae, energy spleen invigorating tonify deficiency, grows essence and reinforce the kidney, control weakness, treat five kinds of strain and seven kinds of impairment." modern medicine study confirms, Rhizoma Dioscoreae can reduce blood glucose, regulates body to non-specific irritant reaction, and effectively the Immunosuppression effect of antagonism cyclophosphamide, stimulates intestinal motility, promotes that intestinal contents is emptying, in addition can also aid digestion, antidiarrheal, eliminate the phlegm.
Rhizoma Smilacis Glabrae: sweet in the mouth; Light; Property is put down.Enter liver; Stomach; Spleen channel.Removing damp-heat; Let out turbid removing toxic substances; Easing joint movement.Cure mainly prunus mume (sieb.) sieb.et zucc. poison; Stranguria with turbid discharge; Have loose bowels; Muscles and bones spasm and pain; Foot gas; Carbuncle; Skin ulcer tinea; Scrofula; Goiter and mercurialism." detailed outline " carries: " curing rheumatism, sharp joint, stopping leak rushes down for strengthening the spleen and stomach, bone and muscle strengthening.Control contracture osteodynia, malignant boil carbuncle, separate hydrargyrum powder, Vermilion poison.”
Ramulus Mori: bitter in the mouth; Property is put down.Enter lung; Kidney two warp.Wind-damp dispelling; Profit joint; Row aqueous vapor.Control anemofrigid-damp arthralgia; Spasm of the limbs; Beriberi edema; Apoplexy and hemiplegia; Human body pruritus due to wind pathogen; For takeing on arm, joint aches is numb." Bencao Tujing " carries: " treat all over body pruritus due to wind pathogen dry, beriberi pathogenic wind, spasm of the limbs." modern medicine study confirmation, Ramulus Mori has obvious curative effects to scapulohumeral periarthritis, can prevent and treat II district flexor tendon postoperative adhesions.
Native Radix Ophiopogonis: sweet in the mouth; Micro-hardship; Cold nature.GUIXIN; Lung; Stomach warp.YIN nourishing and the production of body fluid promoting; Lung moistening clears away heart-fire.Cure mainly dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation." Mingyi Bielu " carries: " Radix Ophiopogonis treats heavy sensation of the body icteric sclera, and rami cardiaci inferiores is full, asthenia exopathogenic heat, xerostomia excessive thirst, anti-nausea, and more flaccidity falls, and reinforcing YIN-essence benefit essence, during rapid digestion of food is adjusted, protects god, determine lung qi, settling five organs, makes us fertile strong." modern medicine study confirms; contain the compositions such as multiple steroid saponin, carotene, phlegmatic temperament, saccharide, stigmasterol Radix Ophiopogonis; have leukocyte increasing; extend the effect of antibody life period; improve immunologic function and nucleic acid synthetic ratio; the generation of the immune materials such as enhancing antibody, complement, interferon, lysozyme simultaneously, have and strengthen healthy energy, strengthen anti-heresy effect.
Rhizoma Zingiberis: acrid in the mouth; Hot in nature.Return spleen; Stomach; The heart; Lung meridian.There is warming spleen and stomach for dispelling cold; Recuperating depleted YANG is promoted blood circulation; Warming the lung to resolve fluid-retention.Cure mainly coldness and pain in the epigastrium; Vomiting; Have loose bowels; YANG-depletion is fainted inverse; Cold fluid-retention is breathed with cough; Arthralgia due to cold-dampnes." property of medicine opinion " carries: control ache in waist kidney cold, cold air, removing blood stasis, removes wind, and logical extremities joint, opens the vital organs of the human body, go the cold numbness of pathogenic wind toxic, night many urine.Control and cough, main warming middle-JIAO, cholera is more than, stomachache, and the full cold-dysentery of relieving distension, controls blood and close.Patient is empty and cold, should add and use it.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Return spleen; Stomach warp.Invigorating the spleen and benefiting QI; Dampness diuretic; Hidroschesis; Antiabortive.Cure mainly deficiency-weakness of spleen-QI; Spiritlessness and weakness; Lack of appetite abdominal distention; Large loose stool is thin; Fluid-retention stagnating in the interior; Dysuria; Edema; Dizziness due to fluid-retention; Arthralgia chiefly caused by damp pathogen is ached; Spontaneous sweating due to deficiency of QI; Frequent fetal movement." herbal classic is met former " carries: " art, raw with there being dehumidifying benefit dry, expectorant diuretic, controls anemofrigid-damp arthralgia, dead flesh convulsion subcutaneous ulcer, blood between loose waist umbilicus, and chong channel is disease, the merit of inverse gas pain in the abdomen; Make ripe, have and middle QI invigorating, slake thirst and help produce saliva, hidroschesis heat extraction, enters diet, antiabortive effect." modern medicine study confirmation, the Rhizoma Atractylodis Macrocephalae has effect that is strong and raising body resistance against diseases, strengthen the phagocytic function of reticuloendothelial system, strengthen the function of leukocytes phagocytic staphylococcus aureus, leukogenic effect is had to leukopenia, improve lymhocyte transformation rate, promote cellular immune function, to staphylococcus aureus, Hemolytic streptococcus, viridans streptococci, streptococcus pneumoniae, meningococcus, diphtheria corynebacterium, bacillus subtilis has inhibitory action in various degree, to acrothesium floccosum, star-shaped nocardia, trichophyton, the dermatophytess such as Trichophyton concentricunm have certain inhibitory action.
Rhizoma Alismatis: sweet in the mouth; Light; Cold in nature.Return kidney; Urinary bladder channel.Promoting diuresis to eliminate damp pathogen; Expel the heat-evil treating stranguria.Cure mainly dysuria; The puckery pain of pyretic stranguria; Edema distension; Have loose bowels; Dizziness due to fluid-retention; Seminal emission." not Lu " carries: " tonifying deficiency five kinds of over strain, except the five internal organs feeling of fullness, plays cloudy gas, stopping leak essence, quenches one's thirst, drenches drop, cuts off the water by bladder, three Jiao." modern medicine study confirmation, Rhizoma Alismatis has reduction cholesterol and atherosclerosis effect, improves liver lipid metabolism, reduces blood glucose, blood pressure, affects function of immune system, reduces serum hemolysin.
Radix Dipsaci: bitter in the mouth; Pungent; Slightly warm in nature.Return liver; Kidney channel.Invigorating the liver and kidney; Bone and muscle strengthening; Blood circulation regulating; Continuous injured; Only metrorrhagia.For back ache; Podomere flaccidity syndrome and arthralgia syndrome; Fall and flutter wound; Damage dish folding bone; Carbuncle skin ulcer swells." Standards of Diagnosis and Treatment " carry: " sweet temperature is supporing yang, pungent with dissipating blood stasis, has liver and kidney tonifying concurrently, strong bone strengthening, the merit of promoting blood circulation." modern medicine study confirmation, Radix Dipsaci contains multiple alkaloid and Trace Element Titanium, has the effect of vitamin antagonist E deficiency disease, carbuncle and ulcer is had to the effect of evacuation of pus, hemostasis, analgesia, promotion tissue regeneration.
Radix Angelicae Sinensis: sweet in the mouth; Pungent; Warm in nature.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation; Menstruction regulating and pain relieving; Loosening bowel to relieve constipation.Cure mainly blood deficiency and yellow complexion; Dizzy cardiopalmus; Asthenia cold abdominalgia; Rheumatic arthralgia; Injury from falling down; Ulcer sores." book on Chinese herbal medicine is just " carries: " its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, can support nutrition blood, QI invigorating spermatogenesis, settling five organs, strong body, beneficial mind, all tangible deficient diseases, nothing unsuitable." modern medicine study confirmation, Radix Angelicae Sinensis has antibacterial, antiinflammation, has obvious inhibitory action to chronic articular rheumatism acute attack.
Semen Abutili: sweet in the mouth; Cold.Return large intestine; Small intestinal; Liver; Lung; Stomach; Urinary bladder channel.There is relieving stranguria by diuresis; Laxation relieving constipation; Stimulating milk secretion.Cure mainly gonorrhea; Edema; Constipation; Breast antiperspirant is not all right.Modern medicine study confirms, Semen Abutili has diuretic; Spleen invigorating; The effect such as to calm the nerves.
Radix Ginseng: bitter in the mouth; Micro-hardship; Slightly warm in nature.Return lung; The spleen heart; Kidney channel.There is strongly invigorating primordial QI; Invigorating the spleen and replenishing QI; Promoting the production of body fluid to quench thirst; Benefit of calming the nerves is short.Cure mainly impairment caused by overstrain deficient; Lack of appetite; Asthenia; Food is told in regurgitation; Stool lingering diarrhea; Empty cough with asthma is urged; Spontaneous perspiration sudden collapse; Palpitation with fear; Forgetful; Dizziness and headache; Sexual impotence; Frequent micturition; Quench one's thirst; Woman uterine bleeding; Children's's intermittent infantile convulsion; Prolonged deficiency is not multiple; The card of qi-blood-body fluid deficiency.
Rhizoma Chuanxiong: acrid in the mouth; Warm in nature.Return liver; Gallbladder; Pericardium channel.Blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping.Zhu Zhi WEIJIA lump; Pain in chest and hypochondrium; Have a headache dizzy; Anemofrigid-damp arthralgia; Traumatic injury; Ulcer sores." book on Chinese herbal medicine just " carries: " dispersing wind and cold, control pain, removing blood stasis with potent drugs stores, promoting blood circulation, separates stagnation of QI, and by pain, evacuation of pus is subsided a swelling, and stimulates the menstrual flow by blood." modern medicine scientific research discovery; Rhizoma Chuanxiong extracting solution has certain effect to suppression leukaemia; preparation has certain antibacterial action; especially all have inhibitory action to Bacillus typhi, Salmonella paratyphi, vibrio cholera, bacillus pyocyaneus and pathogenic dermatophytes etc.; the ligustrazine contained by Rhizoma Chuanxiong, ferulic acid are received has blood circulation invigorating efficacies; expansible coronary artery, promote coronary flow, allevating angina pectoris, and there is anti-thrombosis function, contained cnidium lactone has smooth muscle spasmolysis and suppresses the effect such as myenteron, uterine contraction.
Cortex Acanthopancis: acrid in the mouth; Bitter; Micro-sweet; Warm in nature.Return liver; Kidney channel.There is wind-damp dispelling; Invigorating the liver and kidney; Bone and muscle strengthening; To invigorate blood circulation arteries and veins.Cure mainly anemofrigid-damp arthralgia; Lumbocrural pain; Muscles and bones flaccidity is soft; The decimal a little walking retardation in children; Body void is frail; Traumatic injury; Fracture; Edema; Foot gas; Uncontrolled urination is itched." Shaanxi Chinese herbal medicine " carries: promoting blood circulation and detumescence, dispelling the wind and dampness pathogens arthralgia, eczema scrotum, traumatic injury, edema, dysuria.
Radix Paeoniae Rubra: bitter in the mouth; Be slightly cold.Return Liver Channel.Clearing away heat and cooling blood; Eliminating stasis to stop pain.Cure mainly maculae caused by violent heat pathogen, hematemesis and epistaxis; Conjunctival congestion and swelling pain; Hypochondriac pain due to stagnation of liverQI; Amenorrhea dysmenorrhea; Lump in the abdomen is suffered from abdominal pain; Injury from falling down; Carbuncle skin infection.Shennong's Herbal carries: " bitter in the mouth is put down, main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending cold and heat hernia abdominal mass, pain relieving, and raw Semen Coicis." modern medicine study confirms; Radix Paeoniae Rubra changes to the viscid blood patients with coronary heart disease of height the effect of hemorheological property; can make whole blood viscosity when erythrocyte electrophoretic time reduce; by affect calcium metabolism antagonism atherosclerosis; water-alcohol extraction has significant sedation and analgesic effect; slightly can improve the acidity of gastric juice, can be used for improvement appetite, digestive function and some neuropathy.
Radix Stephaniae Tetrandrae: bitter in the mouth; Pungent; Cold in nature, flat.Return liver; Spleen; Kidney; Taiyang channel.Wind-expelling pain-stopping; Clearing away heat and promoting diuresis.Cure mainly damp and hot general pain; Rheumatic arthralgia; Lower limbs edema; Dysuria; Beriberi swells and ache." not Lu " carries: " treat edema, swelling due to wind, go bladder heat, typhoid fever cold and heat pathogen, apoplexy hands muscle spasm of the leg and foot, stopping leak, loose carbuncle dislikes knot, controls all Guo copperworm skin ulcers, logical space between skin and muscles, sharp nine orifices." modern medicine study discovery; the mufangchine contained by Radix Stephaniae Tetrandrae has the central inhibitory actions such as calmness, antiinflammatory, analgesia and cooling, and having anti-allergic effects widely, is the antagonist of Anaphylactic mediator; be also the blocker of Anaphylactic mediator; can strengthen the contractility of heart, has protective effect to myocardial infarction, can expand coronary vasodilator; reduce blood pressure; loose striped muscle, resisting pathogenic microbes, and significant antitumaous effect.
Radix Scutellariae: bitter in the mouth; Cold in nature.Return lung; Gallbladder; Spleen; Stomach; Large intestine; Small intestine meridian.Heat clearing and damp drying; Eliminating fire and detoxication; Arresting bleeding and miscarriage prevention; Blood pressure lowering.Cure mainly hygropyrexia, heat-damp in summer vomiting and nausea uncomfortable in chest; Damp and hot feeling of fullness; Dysentery; Jaundice; Cough due to lung-heat; Heat in blood tells nosebleed; Carbuncle sore tumefacting virus; Frequent fetal movement." herbal classic " carries: " main all hot jaundice, intestinal is out-of-the-way, lets out profit, relieves oedema or abdominal distension through diuresis or purgation, and hematochezia closes, malignant boil, and cellulitis is lost, acute scleritis." modern medicine study confirms, Radix Scutellariae has the effect such as antibacterial, antifungal, antiviral, antiinflammatory, antiallergic action significantly, can reduce blood pressure, anticoagulant, anticoagulant, blood fat reducing, to protect the liver in addition in addition, function of gallbladder promoting, antioxidation, anticancer function.
Pericarpium Arecae: acrid in the mouth; Slightly warm in nature.Enter spleen; Stomach; Large intestine; Small intestine meridian.Therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO; Line water detumescence.Cure mainly breast abdominal distention vexed; Edema; Foot gas; Dysuria." book on Chinese herbal medicine is new again " carries: " dampness removing chases after wind for eliminating the pathogens from the lung, easing stomach-QI, wide intestinal detumescence, reason waist beriberi, treating malaria disease dysentery." modern medicine study confirms, Pericarpium Arecae can improve intestinal tube tonicity, reduces shrinkage amplitude, has the function regulating intestinal smooth muscle.
The present invention compared with prior art, has following beneficial effect:
The present invention selects medical material to meet a monarch and his subjects left side and makes it reason, compel cardiopulmonary type for insufficiency of the spleen pattern of syndrome, kidney yang deficiency syndrome, water, edema during pregnancy that stagnation of QI water retention type, cold-damp pattern of syndrome cause, there is heat clearing away of nourishing blood, removing dampness detumescence, warming the kidney to promote diuresis, spleen invigorating be antiabortive, regulating qi-flowing for activating stagnancy, cold expelling dry, effect of activating YANG for promoting diuresis.Have no adverse reaction to parent, embryo, fetus through clinical verification medicine of the present invention, do not occur teratogenesis phenomenon, assimilation effect is better, and be convenient for carrying, cure rate is up to 90%.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Effective Component of Chinese Medicine of the present invention and weight are:
Rhizoma Dioscoreae 25g Rhizoma Smilacis Glabrae 25g Ramulus Mori 25g soil 25g Radix Ophiopogonis
Rhizoma Zingiberis 10g Rhizoma Atractylodis Macrocephalae 10g Rhizoma Alismatis 10g Radix Dipsaci 10g Radix Angelicae Sinensis 10g
Semen Abutili 10g Radix Ginseng 10g Rhizoma Chuanxiong 5g Cortex Acanthopancis 5g
Radix Paeoniae Rubra 5g Radix Stephaniae Tetrandrae 5g Radix Scutellariae 5g Pericarpium Arecae 5g.
The processing step of Chinese medicinal preparation method of the present invention is:
(1) first wheat bran is sprinkled in hot pot, when time cigarette is emerged, Rhizoma Dioscoreae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Alismatis is poured respectively into micro-stir-fry to surface in faint yellow, taking-up, sieve after removing wheat bran and cool, be ground into powder, cross 80 mesh sieves, for subsequent use;
(2) Rhizoma Smilacis Glabrae, Ramulus Mori, native Radix Ophiopogonis, Rhizoma Zingiberis, Semen Abutili, Radix Ginseng, Radix Stephaniae Tetrandrae, Pericarpium Arecae are picked decontamination respectively, be ground into powder, cross 80 mesh sieves, for subsequent use;
(3) Radix Angelicae Sinensis, Rhizoma Chuanxiong, Cortex Acanthopancis, Radix Scutellariae are picked decontamination respectively, clean, section is dried, and gets Radix Angelicae Sinensis Tabellae, Rhizoma Chuanxiong sheet, Cortex Acanthopancis, scutellaria tablet spray shao-hsing rice wine respectively (be 10:1 with shao-hsing rice wine proportion by subtraction), mix thoroughly, extremely surperficial in micro-yellow with the micro-stir-fry of slow fire, take out, cool, be ground into powder, cross 80 mesh sieves, for subsequent use;
(4) Radix Dipsaci, Radix Paeoniae Rubra are gone to pick decontamination respectively, section after cleaning, dry, get Radix Dipsaci sheet, Radix Paeoniae Rubra sheet enters respectively in pot and fry to surperficial micro-Jiao with slow fire, take out, cool, be ground into powder, cross 80 mesh sieves, for subsequent use;
(5) by the powder of step 1, step 2, step 3, step 4 gained, to pour in container mixing into and mix thoroughly, the water adding 9 times amount of dose carries out decoctions to after seething with excitement, continue, with slow fire boiling 40 minutes, to leach medicinal liquid, by the thick paste of relative density 1.20 under the concentration of liquid medicine of filtering most 75 DEG C of environment, carry out cold drying, pulverize, add appropriate dextrin, mixing, granulate, cold drying, granulate, incapsulate, to obtain final product.
Usage and consumption: each 3g ~ 5, every day 2 times, taking with ante cibum, after meal 2 hour, 5 days is 1 course for the treatment of.
Embodiment 2
The raw material composition of Effective Component of Chinese Medicine of the present invention and weight are:
Rhizoma Dioscoreae 17g Rhizoma Smilacis Glabrae 17g Ramulus Mori 17g soil 17g Radix Ophiopogonis
Rhizoma Zingiberis 6g Rhizoma Atractylodis Macrocephalae 6g Rhizoma Alismatis 6g Radix Dipsaci 6g Radix Angelicae Sinensis 6g
Semen Abutili 6g Radix Ginseng 6g Rhizoma Chuanxiong 3.5g Cortex Acanthopancis 3.5g
Radix Paeoniae Rubra 3.5g Radix Stephaniae Tetrandrae 3.5g Radix Scutellariae 3.5g Pericarpium Arecae 3.5g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Effective Component of Chinese Medicine of the present invention and weight are:
Rhizoma Dioscoreae 28g Rhizoma Smilacis Glabrae 28g Ramulus Mori 28g soil 28g Radix Ophiopogonis
Rhizoma Zingiberis 13g Rhizoma Atractylodis Macrocephalae 13g Rhizoma Alismatis 13g Radix Dipsaci 13g Radix Angelicae Sinensis 13g
Semen Abutili 13g Radix Ginseng 13g Rhizoma Chuanxiong 8g Cortex Acanthopancis 8g
Radix Paeoniae Rubra 8g Radix Stephaniae Tetrandrae 8g Radix Scutellariae 8g Pericarpium Arecae 8g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection
Inventor has 240 routine insufficiency of the spleen pattern of syndrome, kidney yang deficiency syndrome, water to compel the clinical observation of cardiopulmonary type, stagnation of QI water retention type, cold-damp pattern of syndrome edema during pregnancy in October, 2005 g ~ 2014 statistics in year March, and patient is divided into two groups at random.Treatment group 120 example, matched group 120 example, the mean age, the course of disease was 15g ~ 28 day, and two groups of qualifications and record of service are basically identical, without significant difference, has comparability in 24g ~ 38 year old.
2, treatment group patient takes medicine of the present invention, and according to the capsule that specific embodiment 1 is obtained, morning and evening service once, each serving 3, take 2 courses for the treatment of, serious symptom person is for take 2 courses for the treatment of each serving 5.Matched group, according to the classification of the edema during pregnancy diagnosed out, gives Fuling Decoction, WUPI YIN respectively, takes to specifications.10 days courses for the treatment of.
3, efficacy determination:
(1) fully recover: foot dish, ankle, finger, the back of the hand, shank, thigh are without swelling phenomenon, and without hypertension symptom, urine detection is without urine protein, and without sensation of oppression over the chest with shortness of breath, stool, urine is normal.
(2) take a turn for the better: without hypertension symptom, urine detection is without urine protein, and foot dish, ankle, finger, shank, thigh swelling alleviate, and without uncomfortable in chest, stool, urine is normal.
(3) invalid: symptom is with treating front no significant difference.
4, result
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Cure rate % | Total effective rate (%) |
| Treatment group | 120 | 86 | 22 | 12 | 71％ | 90％ |
| Matched group | 120 | 56 | 19 | 45 | 46％ | 62.5％ |
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
Case 1
Mrs Qin, 28 years old, patient's readme, conceived 7 first quarter moons, have slight edema, the severity of nearest edema for the previous period, hand, thigh, calf edema, body weight too increases a lot, and at hospital assay urine protein 2+, and blood pressure raises, pale tongue, white and moist fur, deep-slow pulse, stagnation of QI water retention type edema during pregnancy should with the Therapeutic Principle of regulating qi-flowing for activating stagnancy, activating YANG for promoting diuresis.Patient takes Chinese medicine of the present invention 3, edematous site is subsided a swelling gradually, take 5 continuously, symptom disappears substantially, and blood pressure measurement recovers normal value, do urine examination without albuminuria, fetal heart monitoring is normal, goes home to have a rest until come my institute's spontaneous labor boy baby term, shows the indices of baby, do not find teratogenesis phenomenon, it is healthy that after the birth, mother and child were doing well.
Case 2
Ms Zhang, 32 years old, patient's readme, be four months pregnant, occur slight edema, rest a whole night, just recovered in the morning, after one week, edema more severe, be also swollen in the morning, appetite declines, also frequent with uncomfortable in chest, come hospital's Measure blood pressure low pressure 100, high pressure 150, do urine examination and do not find albuminuria, be diagnosed as appearance extremity edema, companion's sensation of oppression over the chest with shortness of breath, inappetence, large loose stool is thin, body of the tongue is fat tender, white and thin fur, moderate pulse is sliding unable, and spleen-deficient edema should the Therapeutic Principle of, removing dampness detumescence antiabortive with spleen invigorating.Patient takes Chinese medicine 1 of the present invention course for the treatment of, and appetite is fabulous, and no longer uncomfortable in chest, edema alleviates, blood pressure 90,120.After continuing to strengthen for 1 course for the treatment of, symptom disappears substantially, then without recurrence, fetal rhythm is normal, and B ultrasonic display fetus is without teratogenesis phenomenon, and visit after half a year, baby is very healthy, does not occur adverse side effect.
Comprehensive above-mentioned visible, Chinese medicine of the present invention effectively can treat the edema during pregnancy of multiple disease type, compel cardiopulmonary type for insufficiency of the spleen pattern of syndrome, kidney yang deficiency syndrome, water, edema during pregnancy that stagnation of QI water retention type, cold-damp pattern of syndrome cause, there is heat clearing away of nourishing blood, removing dampness detumescence, warming the kidney to promote diuresis, spleen invigorating be antiabortive, regulating qi-flowing for activating stagnancy, cold expelling dry, effect of activating YANG for promoting diuresis.Have no adverse reaction to parent, embryo, fetus through clinical verification medicine of the present invention, do not occur teratogenesis phenomenon, assimilation effect is better, and be convenient for carrying, cure rate is up to 90%.
Claims (4)
1. for preventing and treating a Chinese medicine capsules for edema during pregnancy, it is characterized in that, raw material composition and the parts by weight of making described Effective Component of Chinese Medicine are:
Rhizoma Dioscoreae 15 ~ 30 parts of Rhizoma Smilacis Glabraes 15 ~ 30 parts of Ramulus Moris 15 ~ 30 parts of native Radix Ophiopogonis 15 ~ 30 parts
Rhizoma Zingiberis 5 ~ 15 parts of Rhizoma Atractylodis Macrocephalaes 5 ~ 15 portions of Rhizoma Alismatis 5 ~ 15 parts of Radix Dipsacis 5 ~ 15 parts
Radix Angelicae Sinensis 5 ~ 15 parts of Semen Abutilis 5 ~ 15 parts of Radix Ginsengs 5 ~ 15 parts of Rhizoma Chuanxiongs 3 ~ 10 parts
Cortex Acanthopancis 3 ~ 10 parts of Radix Paeoniae Rubra 3 ~ 10 parts of Radixs Stephaniae Tetrandrae 3 ~ 10 parts of Radix Scutellariaes 3 ~ 10 parts
Pericarpium Arecae 3 ~ 10 parts.
2. a kind of Chinese medicine capsules for preventing and treating edema during pregnancy according to claim 1, is characterized in that, raw material composition and the parts by weight of making described Effective Component of Chinese Medicine are:
Rhizoma Dioscoreae 19 ~ 26 parts of Rhizoma Smilacis Glabraes 19 ~ 26 parts of Ramulus Moris 19 ~ 26 parts of native Radix Ophiopogonis 19 ~ 26 parts
Rhizoma Zingiberis 8 ~ 12 parts of Rhizoma Atractylodis Macrocephalaes 8 ~ 12 portions of Rhizoma Alismatis 8 ~ 12 parts of Radix Dipsacis 8 ~ 12 parts
Radix Angelicae Sinensis 8 ~ 12 parts of Semen Abutilis 8 ~ 12 parts of Radix Ginsengs 8 ~ 12 parts of Rhizoma Chuanxiongs 4 ~ 7 parts
Cortex Acanthopancis 4 ~ 7 parts of Radix Paeoniae Rubra 4 ~ 7 parts of Radixs Stephaniae Tetrandrae 4 ~ 7 parts of Radix Scutellariaes 4 ~ 7 parts
Pericarpium Arecae 4 ~ 7 parts.
3. a kind of Chinese medicine capsules for preventing and treating edema during pregnancy according to claim 1, is characterized in that, raw material composition and the parts by weight of making described Effective Component of Chinese Medicine are:
Rhizoma Dioscoreae 25 parts of Rhizoma Smilacis Glabraes 25 parts of Ramulus Moris 25 parts of native Radix Ophiopogonis 25 parts
Rhizoma Zingiberis 10 parts of Rhizoma Atractylodis Macrocephalaes 10 portions of Rhizoma Alismatis 10 parts of Radix Dipsacis 10 parts of Radix Angelicae Sinensis 10 parts
Semen Abutili 10 parts of Radix Ginsengs 10 parts of Rhizoma Chuanxiongs 5 parts of Cortex Acanthopanciss 5 parts
Radix Paeoniae Rubra 5 parts of Radixs Stephaniae Tetrandrae 5 parts of Radix Scutellariaes 5 parts of Pericarpium Arecae 5 parts.
4. the preparation method of a kind of Chinese medicine capsules for preventing and treating edema during pregnancy according to claims 1 to 3, is characterized in that, comprise following processing step:
(1) first wheat bran is sprinkled in hot pot, when time cigarette is emerged, Rhizoma Dioscoreae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Alismatis is poured respectively into micro-stir-fry to surface in faint yellow, taking-up, sieve after removing wheat bran and cool, be ground into powder, cross 80 mesh sieves, for subsequent use;
(2) Rhizoma Smilacis Glabrae, Ramulus Mori, native Radix Ophiopogonis, Rhizoma Zingiberis, Semen Abutili, Radix Ginseng, Radix Stephaniae Tetrandrae, Pericarpium Arecae are picked decontamination respectively, be ground into powder, cross 80 mesh sieves, for subsequent use;
(3) Radix Angelicae Sinensis, Rhizoma Chuanxiong, Cortex Acanthopancis, Radix Scutellariae are picked decontamination respectively, clean, section is dried, and gets Radix Angelicae Sinensis Tabellae, Rhizoma Chuanxiong sheet, Cortex Acanthopancis, scutellaria tablet spray shao-hsing rice wine respectively (be 10:1 with shao-hsing rice wine proportion by subtraction), mix thoroughly, extremely surperficial in micro-yellow with the micro-stir-fry of slow fire, take out, cool, be ground into powder, cross 80 mesh sieves, for subsequent use;
(4) Radix Dipsaci, Radix Paeoniae Rubra are gone to pick decontamination respectively, section after cleaning, dry, get Radix Dipsaci sheet, Radix Paeoniae Rubra sheet enters respectively in pot and fry to surperficial micro-Jiao with slow fire, take out, cool, be ground into powder, cross 80 mesh sieves, for subsequent use;
(5) by the powder of step 1, step 2, step 3, step 4 gained, to pour in container mixing into and mix thoroughly, the water adding 9 times amount of dose carries out decoctions to after seething with excitement, continue, with slow fire boiling 40 minutes, to leach medicinal liquid, by the thick paste of relative density 1.20 under the concentration of liquid medicine of filtering most 75 DEG C of environment, carry out cold drying, pulverize, add appropriate dextrin, mixing, granulate, cold drying, granulate, incapsulate, to obtain final product.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105999007A (en) * | 2016-07-19 | 2016-10-12 | 宓鑫 | Traditional Chinese medicine composition for treating edema |
| CN105999008A (en) * | 2016-07-19 | 2016-10-12 | 宓鑫 | Traditional Chinese medicine composition for treating cyesedema |
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| CN105999008A (en) * | 2016-07-19 | 2016-10-12 | 宓鑫 | Traditional Chinese medicine composition for treating cyesedema |
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