CN105943639A - Traditional Chinese medicine composition assisting in treating chronic subdural hematoma - Google Patents

Traditional Chinese medicine composition assisting in treating chronic subdural hematoma Download PDF

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CN105943639A
CN105943639A CN201610442560.1A CN201610442560A CN105943639A CN 105943639 A CN105943639 A CN 105943639A CN 201610442560 A CN201610442560 A CN 201610442560A CN 105943639 A CN105943639 A CN 105943639A
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chinese medicine
medicine composition
subdural hematoma
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张连纲
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/09Lichens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/37Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/64Orobanchaceae (Broom-rape family)

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  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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Abstract

The invention discloses a traditional Chinese medicine composition assisting in treating chronic subdural hematoma. The traditional Chinese medicine preparation is prepared from gentiana sarcorrhiza Ling et Ma ex T.N.Ho, fruit of leatherleaf mahonia, herb of russian boschniakia, thalli of alectoria asiatica du rietz, polytrichum commune L.ex Hedw., salvia trijuga diels, suffrutescent securinega twigs, stems of oriental bittersweet, roots of tomentoseflower larkspour and dichocarpum auriculatum(Franch.)W.T.Wang et Hsiao. According to the traditional Chinese medicine composition assisting in treating the chronic subdural hematoma, the reoperation rate can be decreased, the curative effect is improved, the hospitalization time is shortened, the economical burden of a patient is reduced, and the traditional Chinese medicine composition is easy to accept by the patient and family members.

Description

A kind of Chinese medicine composition assisting treatment chronic subdural hematoma
Technical field
The present invention relates to Chinese medicine sciemtifec and technical sphere, treat chronic cerebral dura mater particularly to one auxiliary The Chinese medicine composition of lower hematoma.
Background technology
Chronic subdural hematoma is one of neurosurgery common disease, is apt to occur in more than 50 years old Crowd.Before morbidity, slowly there is chronic intracranial pressure in nothing or the slightest injury of head history Increase, the symptom such as slight hemiplegia, epilepsy, hypomnesis and dysnoesia, easily by mistaken diagnosis, Make patient can not obtain the treatment of timely specification, cause the delay of the state of an illness and the wave of medical resource Take.Treatment the most in time, this disease prognosis is preferable.Clinical first-selected Drilling and drainage, but art Rear convalescent period length and easily recurring.Chinese medicine cerebrovascular have accumulated rich experiences, Use for reference the experience of Chinese medicine cerebrovascular, develop auxiliary treatment chronic subdural hematoma Chinese medicine composition, there is important clinical significance.
Summary of the invention
It is an object of the invention to overcome the above-mentioned deficiency in the presence of prior art, i.e. provide A kind of Chinese medicine composition assisting treatment chronic subdural hematoma.
In order to realize foregoing invention purpose, the invention provides techniques below scheme:
A kind of Chinese medicine composition assisting treatment chronic subdural hematoma, by following mass ratio The crude drug of example is made:
Radix Gentianae sarcorrhizae 9-15 part, Fructus Mahoniae 6-10 part, Herba Boschniakiae Rossicae 15-25 part, Alectoria asiatica Du Rietz 9-15 Part, soil Iuba Equi 10-20 part, salvia trijuga Diels 3-9 part, a leaf 6-12 part, Celastrus orbiculatus Thunb. Really 9-15 part, Rhizoma Arisaematis 3-9 part, sow grass 3-9 part.
Radix Gentianae sarcorrhizae: hardship sweet, micro-, temperature.Lung benefiting kidney, reducing the asthenic fever.Cure mainly cough due to deficiency of the lung, kidney Empty seminal emission, the enuresis, deficient fever, body is empty after being ill, dizzy dreaminess, spontaneous perspiration, and night sweat is little Youngster's infantile malnutrition.
Fructus Mahoniae: bitter, cool.Tonifying the lung, kidney tonifying, clearind deficient heat.Cure mainly pulmonary tuberculosis, osteopyrexia and fever, Spitting of blood, soreness of the waist and knees, dizziness and tinnitus, metrorrhagia, leukorrhagia, stranguria with turbid discharge.
Herba Boschniakiae Rossicae: sweet, salty, warm.Kidney invigorating and YANG supporting, loosening bowel to relieve constipation, hemostasis.Cure mainly and suffer from a deficiency of the kidney Sexual impotence, seminal emission, chills and pain of the waist and kness, urine something lost drip, hematuria, cold womb is infertile, metrorrhagia, leukorrhagia, Dryness of the intestine constipation.
Alectoria asiatica Du Rietz: light, flat.YIN nourishing, diuretic, astringent therapy hidroschesis.Cure mainly kidney deficiency and bodily weakness, head Dizzy dizzy, cardiopalmus, night sweat of passing out semen, stranguria, edema, impetigo.
Soil Iuba Equi: sweet, cold.Nourishing YIN and clearing away heat, cooling blood for hemostasis, loosening bowel to relieve constipation.Cure mainly the deficiency of YIN Hectic fever due to YIN-deficiency, hectic fever night sweat, pulmonary tuberculosis cough, heat in blood haematemesis, epistaxis, spitting of blood, have blood in stool, metrorrhagia, Constipation and anuresis.
Salvia trijuga Diels: bitter, micro-sweet, warm, returns liver, the heart, kidney channel.Promoting blood flow to regulate menstruation, dispels Stasis of blood tissue regeneration promoting, kidney tonifying is calmed the nerves.Cure mainly menoxenia, dysmenorrhea, amenorrhea, metrorrhagia, lumbago due to renal deficiency, Sexual impotence, insomnia, dreaminess, traumatic injury.
One leaf: pungent, bitter, tepor, slightly poisonous.Expelling wind and activating blood circulation, the strong muscle of kidney tonifying.Cure mainly Lumbago due to pathogenic wind-dampness, sexual impotence, dizziness, tinnitus, deaf, facial paralysis, poliomyelitis sequela.
Fruits of Celastrus orbiculatus Thunb: hardship sweet, micro-, flat.Tranquilizing by nourishing the heart, regulating blood flow to alleviate pains.Cure mainly cardiopalmus, Insomnia, forgetful dreaminess, toothache, bones and muscles pain, waist-leg is numb, traumatic pain.
Rhizoma Arisaematis: pungent, bitter, flat.Tranquilizing by nourishing the heart, liver heat removing and eyesight improving.Cure mainly severe palpitation, Neurasthenia, conjunctival congestion and swelling pain, coronary heart disease etc..
Sow grass: bitter, cold.Removing damp-heat, eliminating stagnation is reduced phlegm.Cure mainly jaundice due to damp-heat, carbuncle Sore, scrofula, phlegm-heat cough, epilepsy.
Chinese medicine is thought, gerontal patient's kidney qi virtual loss usually, the dirty imbalance of YIN and YANG of heart kidney liver three, Brain key loses in moistening foster.Though slight wound, venation is fragile, and hyperamization is overflow outside arteries and veins, produces one Series symptom.Control suitable nourishing kidney-yin, kidney tonifying sun, removing stasis to stop bleeding, tranquilizing by nourishing the heart.The present invention adopts By Radix Gentianae sarcorrhizae, Fructus Mahoniae kidney tonifying, clearind deficient heat;Herba Boschniakiae Rossicae kidney invigorating and YANG supporting, hemostasis;Alectoria asiatica Du Rietz, Soil Iuba Equi nourishing yin and stopping bleeding;Salvia trijuga Diels, a leaf blood circulation promoting and blood stasis dispelling, kidney tonifying is calmed the nerves;South Serpentis Rattan fruit, Rhizoma Arisaematis tranquilizing by nourishing the heart;Sow grass eliminating stagnation is reduced phlegm.All medicines share, the kidney invigorating gas, tune Negative and positive to effect a permanent cure, removing stasis to stop bleeding to take stopgap measures, treating both the principal and secondary aspects of a disease, effect of wining a battle altogether.
Preferably, the Chinese medicine composition of described auxiliary treatment chronic subdural hematoma is by following The crude drug of mass ratio is made:
Radix Gentianae sarcorrhizae 12 parts, Fructus Mahoniae 8 parts, Herba Boschniakiae Rossicae 20 parts, Alectoria asiatica Du Rietz 12 parts, soil 15 parts of Iuba Equi, salvia trijuga Diels 6 parts, 9 parts of a leaf, fruits of Celastrus orbiculatus Thunb 12 parts, one 6 parts of umbrella, sow grass 6 parts.
The Chinese medicine composition of described auxiliary treatment chronic subdural hematoma can use existing Chinese medicine preparation technology is prepared as any conventional oral preparations, such as, can said components be used Decocting obtains water decoction, it is also possible to described auxiliary controlled by other existing Chinese medicine preparation technology Treat chronic subdural hematoma Chinese medicine preparation be prepared as honeyed pill, condensed water honeyed pill, the watered pill, Granule, capsule, tablet, powder, unguentum, oral liquid.
Compared with prior art, beneficial effects of the present invention
The Chinese medicine composition of the auxiliary treatment chronic subdural hematoma that the present invention provides, can drop Low operability again, improves curative effect, shortens the hospital stays, alleviates the financial burden of patient, Patient and family members are prone to accept.
A kind of Chinese medicine composition assisting treatment chronic subdural hematoma, clinical efficacy is summed up
1, physical data
103 example chronic subdural hematoma patients are randomly divided into treatment group and matched group.Treatment Organize 52 examples, male 37 examples, female 15 example;48.5 ± 3.12 years old age.Matched group 51 example, Man's 38 examples, female 13 example, 47.8 ± 3.25 years old age.Clinical symptoms with increased intracranial pressure is Main or focal symptom is main or mental disorder is main, therapeutic component is not 31,14, 7 examples, matched group is respectively 33,12,6 examples.CT hematoma density be low, etc., high density Person's therapeutic component is not 25,24,3 examples, and matched group is respectively 26,22,3 examples.Above Compare between each item data 2 groups, no significant difference (P > 0.05), there is comparability.
2, Therapeutic Method
Matched group patient's row Drilling and drainage routine medication, treatment group is in above-mentioned treatment On the basis of be administered orally simultaneously the present invention provide Chinese medicine composition water decoction:
Radix Gentianae sarcorrhizae 12 grams, Fructus Mahoniae 8 grams, Herba Boschniakiae Rossicae 20 grams, Alectoria asiatica Du Rietz 12 grams, soil 15 grams of Iuba Equi, salvia trijuga Diels 6 grams, 9 grams of a leaf, fruits of Celastrus orbiculatus Thunb 12 grams, one 6 grams of umbrella, sow grass 6 grams.Making water decoction according to conventional Chinese medicine preparation technology, everyone is every Day potion.
3 therapeutic outcomes
3.1 criterions of therapeutical effect: with reference to " clinical disease diagnosis is according to curing improvement standard " (China The people Xie Jun General Logistics Department. clinical disease diagnosis is according to curing and improvement standard. Beijing: the People's Army Doctor publishing house, 1987.426) criterion of therapeutical effect: 1. cure: compression of brain symptom is improved completely, Myodynamia recovery is normal, and intracranial hypertension symptom complete incidence graph, be a cup too low symptom, CT examination blood Swollen disappearance;The most effective: compression of brain symptom is improved substantially, more than Myodynamia recovery to IV level, cranium Inner high voltage symptom complete incidence graph, the symptom that is a cup too low, CT examination pressurized cerebral tissue fail completely Swelling, hematoma is obviously reduced;The most invalid: compression of brain symptom fails to be improved, muscular strength without Improving, intracranial hypertension symptom fails to be eased, and original mental symptom still suffers from, and CT examines Look into pressurized cerebral tissue to fail to swell, need to again go and bore cranium irrigation and drainage art or open cranium art.
3.2, result: 2 groups of average hospital days, hematoma extinction time, therapeutic effect compare, and see Table 1.
Table 1,2 groups of average hospital days, hematoma extinction time, therapeutic effect compare
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in further detail.But should not This is interpreted as, and the scope of the above-mentioned theme of the present invention is only limitted to below example, all based on this The technology that summary of the invention is realized belongs to the scope of the present invention.
Embodiment 1
A kind of Chinese medicine composition assisting treatment chronic subdural hematoma, is by Radix Gentianae sarcorrhizae 15 grams, Fructus Mahoniae 10 grams, Herba Boschniakiae Rossicae 25 grams, Alectoria asiatica Du Rietz 15 grams, soil 20 grams of Iuba Equi, Salvia trijuga Diels 9 grams, 12 grams of a leaf, fruits of Celastrus orbiculatus Thunb 15 grams, Rhizoma Arisaematis 9 grams, mother Pigweed 9 grams makes water decoction according to conventional Chinese medicine preparation technology, everyone potion every day.
Embodiment 2
A kind of Chinese medicine composition assisting treatment chronic subdural hematoma, is by Radix Gentianae sarcorrhizae 12 Gram, Fructus Mahoniae 8 grams, Herba Boschniakiae Rossicae 20 grams, Alectoria asiatica Du Rietz 12 grams, soil 15 grams of Iuba Equi, three To leaf Radix Salviae Miltiorrhizae 6 grams, 9 grams of a leaf, fruits of Celastrus orbiculatus Thunb 12 grams, Rhizoma Arisaematis 6 grams, sow Grass 6 grams makes water decoction according to conventional Chinese medicine preparation technology, everyone potion every day.
Embodiment 3
A kind of Chinese medicine composition assisting treatment chronic subdural hematoma, is by Radix Gentianae sarcorrhizae 9 Gram, Fructus Mahoniae 6 grams, Herba Boschniakiae Rossicae 15 grams, Alectoria asiatica Du Rietz 9 grams, 10 grams of Iuba Equi of soil, three right Leaf Radix Salviae Miltiorrhizae 3 grams, 6 grams of a leaf, fruits of Celastrus orbiculatus Thunb 9 grams, Rhizoma Arisaematis 3 grams, sow grass 3 Gram make water decoction according to conventional Chinese medicine preparation technology, everyone potion every day.
Chinese medicine composition in embodiment 1-3, it is also possible to according to the Chinese medicine of described mass ratio Component is prepared as honeyed pill, condensed water honeyed pill, the watered pill, granule, capsule according to States Pharmacopoeia specifications Agent, tablet, powder, unguentum, oral liquid.Its effect is identical with water decoction effect.

Claims (3)

1. assisting a Chinese medicine composition for treatment chronic subdural hematoma, its feature exists In being made up of the crude drug of following mass ratio:
Radix Gentianae sarcorrhizae 9-15 part, Fructus Mahoniae 6-10 part, Herba Boschniakiae Rossicae 15-25 part, Alectoria asiatica Du Rietz 9-15 Part, soil Iuba Equi 10-20 part, salvia trijuga Diels 3-9 part, a leaf 6-12 part, Celastrus orbiculatus Thunb. Really 9-15 part, Rhizoma Arisaematis 3-9 part, sow grass 3-9 part.
2. the Chinese drug-treated group of auxiliary treatment chronic subdural hematoma as claimed in claim 1 Compound, it is characterised in that be made up of the crude drug of following mass ratio:
Radix Gentianae sarcorrhizae 12 parts, Fructus Mahoniae 8 parts, Herba Boschniakiae Rossicae 20 parts, Alectoria asiatica Du Rietz 12 parts, soil 15 parts of Iuba Equi, salvia trijuga Diels 6 parts, 9 parts of a leaf, fruits of Celastrus orbiculatus Thunb 12 parts, one 6 parts of umbrella, sow grass 6 parts.
3. auxiliary treats the Chinese medicine composition of chronic subdural hematoma as claimed in claim 1 The preparation method of thing, it is characterised in that the Chinese medicinal components of described mass ratio is prepared as decocting Agent, honeyed pill, condensed water honeyed pill, the watered pill, granule, capsule, tablet, powder, cream Agent, oral liquid.
CN201610442560.1A 2016-06-16 2016-06-16 Traditional Chinese medicine composition assisting in treating chronic subdural hematoma Pending CN105943639A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2742254C1 (en) * 2020-09-29 2021-02-04 федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр имени В.А. Алмазова" Министерства здравоохранения Российской Федерации Surgical treatment method for chronic subdural hematomas

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104587199A (en) * 2014-12-30 2015-05-06 青岛大学附属医院 traditional Chinese medicine composition for treating chronic subdural hematoma, as well as preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104587199A (en) * 2014-12-30 2015-05-06 青岛大学附属医院 traditional Chinese medicine composition for treating chronic subdural hematoma, as well as preparation method thereof

Non-Patent Citations (1)

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Title
王启才,杨卓欣: "《针灸医学宝典》", 31 October 2014, 中医古籍出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2742254C1 (en) * 2020-09-29 2021-02-04 федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр имени В.А. Алмазова" Министерства здравоохранения Российской Федерации Surgical treatment method for chronic subdural hematomas

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Application publication date: 20160921