CN102274385A - Medicament for treating nasosinusitis and preparation method thereof - Google Patents
Medicament for treating nasosinusitis and preparation method thereof Download PDFInfo
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- CN102274385A CN102274385A CN 201110222989 CN201110222989A CN102274385A CN 102274385 A CN102274385 A CN 102274385A CN 201110222989 CN201110222989 CN 201110222989 CN 201110222989 A CN201110222989 A CN 201110222989A CN 102274385 A CN102274385 A CN 102274385A
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Abstract
The invention belongs to the technical field of Chinese patent medicines and specifically relates to a medicament for treating nasosinusitis and a preparation method thereof. The medicament is mainly used for solving the problems that the existing method for treating the nasosinusitis can not only bring suffering at a certain extent to a patient, but also only treat the symptoms but not the root cause of the disease and enable the nasosinusitis to be easy to recur. The medicament for treating the nasosinusitis comprises the following active pharmaceutical ingredients: siberian cocklour fruit, biond magnolia flower, dahurian angelica root, manchurian wildginger, peppermint, raw gypsum and green onion; and the active pharmaceutical ingredients are decocted with water twice for preparing decoction. The medicament has the advantages of low cost, fast onset of action, short treatment course, no toxic or side effects and the like.
Description
Technical field
The invention belongs to the Chinese Traditional Medicines technical field, be specifically related to a kind of medicine for the treatment of sinusitis and preparation method thereof.
Background technology
Sinusitis is the very high disease of a kind of sickness rate, if treat untimelyly, can bring out various complication, and is bigger to the health of human body menace.This patient crowd and wide, but mostly be children, the lighter's dizziness headache, directly influence study, weight person is absent minded, hypomnesis, so that IQ obviously descends.The traditional Chinese medical science thinks that bringing out this sick main cause is that whole body is lower for the resistance, overtired, suffer from cold and wet, malnutrition, vitamin deficiency, and living environment bad due to.The patient who has is by having an injection, and puncture for treating is perhaps adopted in transfusion, and these Therapeutic Method not only make the patient suffer greatest misery, and all are to control table not effect a permanent cure, and sinusitis can not be fundamentally treated in recurrence easily.
Summary of the invention
The method that the present invention is primarily aimed at present treatment sinusitis is not only brought to a certain degree misery to the patient, and controls table and do not effect a permanent cure, and the problem of recurrence easily provides a kind of cure rate height, treating both the principal and secondary aspects of a disease and the medicine of the treatment sinusitis that do not recur.
The present invention also provides the preparation method of this medicine.
The technical scheme that the present invention takes for achieving the above object is:
A kind of medicine for the treatment of sinusitis is to be crude drug with following parts of medicines by weight:
30～45 parts of 12～15 parts of Fructus Xanthii, 12～15 parts of Flos Magnoliaes, 6～9 parts of the Radixs Angelicae Dahuricae, 2～4 parts of Herba Asaris, 6～8 parts of Herba Menthaes, 30～45 parts of Gypsum Fibrosum and Herba Alii fistulosis; Wherein said Herba Alii fistulosi must Herba Alii fistulosi for band.
System and the symptom different according to the patient also comprise in the following portions by weight crude drug one or more:
10～15 parts of 9～12 parts in Herba Ephedrae, 15～20 parts of Herba Houttuyniae, 12～15 parts of Radix Salviae Miltiorrhizaes, 15～18 parts of Radix Pseudostellariaes or Spina Gleditsiaes.
Medicine of the present invention can be made the dosage form on any pharmaceutics, and as decoction, powder, pill, capsule, tablet etc., wherein the preferred dosage form of the present invention is a decoction.
The preparation method that the present invention treats the medicine of sinusitis is: get above-mentioned parts of medicines by weight in container, the water logging that adds 6～8 times was steeped 1～1.5 hour, fry in shallow oil to boiling with very hot oven, kept 15～20 minutes, pour out decocting liquid, in container, add 4～5 times water again, the reuse very hot oven is fried in shallow oil to boiling, keeps 10～15 minutes, pours out decocting liquid, merge decocting liquid twice, sterilization is made.
Fructus Xanthii in the prescription of the present invention: warm in nature, acrid in the mouth, hardship is gone into lung meridian, has diffusing rheumatism, and the effect of clearing the nasal passage is used for the treatment of headche due to wind-cold, the nasal sinusitis watery nasal discharge; Flos Magnoliae: warm in nature, acrid in the mouth is gone into lung meridian, has the effect of the clearing the nasal passage of dispeling the wind, and is used for the treatment of headache, nasal sinusitis, and it is obstructed to have a stuffy nose; The Radix Angelicae Dahuricae: warm in nature, acrid in the mouth is gone into lung stomach warp, has expelling pathogenic wind from the body surface, pain relieving, and detumescence, the effect of evacuation of pus is used for the treatment of flu, wind and cold, headache, nasal obstruction; Herba Asari: warm in nature, acrid in the mouth is gone into the lung kidney channel, the energy wind-expelling pain-stopping, and the cold expelling of having one's ideas straightened out, main treatment flu, headache is had a stuffy nose; Herba Menthae: cool in nature, flavor is cold, returns lung, Liver Channel, and dispelling wind-heat, the clear sharp head is used for the treatment of anemopyretic cold, and epidemic febrile disease is from the beginning of, headache conjunctival congestion; Gypsum Fibrosum: cool in nature, cold, acrid in the mouth is gone into lung stomach two warps, has clearing away heat-fire, and the effect of collateral dredging is used for the lung heat clearing gastric heat, the detoxifcation pain relieving, and relieving restlessness is promoted the production of body fluid, and quenches the thirst; Herba Alii fistulosi: warm in nature, acrid in the mouth is gone into lung meridian, and the tying-in clearing the nasal passage is arranged, and the effect of refreshment order can make all medicine efficacy of a drug sick institute that goes directly; Herba Ephedrae: warm in nature, acrid in the mouth is gone into lung meridian, has the effect of dispersing wind-cold, is used for relieving the exterior syndrome by diaphoresis, and lung qi dispersing quenches the thirst; Herba Houttuyniae: cold nature, cold, acrid in the mouth is gone into lung, and the stomach warp has the heat radiation detumescence, and the effect of removing pathogenic heat from blood and toxic substance from the body is used for clearing away lung-heat lung heat clearing fire; Radix Salviae Miltiorrhizae: cold nature, bitter in the mouth, GUIXIN lung two warps can promoting blood circulation to remove obstruction in the collateral, stasis-dispelling and pain-killing, tranquilizing by nourishing the heart is used for the eliminating carbuncle pain relieving, and treatment calentura coma can also blood-cooling and spirit-quieting; Radix Pseudostellariae: cold nature, sweet in the mouth, little hardship is gone into lung, spleen, stomach three warps, have analgesic, antiinflammatory, antibiotic, antiviral, the effect of influenza is used for the treatment of weakness of the spleen and stomach, inappetence, interior-heat is thirsty; Spina Gleditsiae: warm in nature, acrid in the mouth, salty, go into the heart, lung, spleen three warps can be invigorated blood circulation, and dispel the wind, and search wind, draw out pus by applying a plaster to the affected part, detumescence, evacuation of pus is used for the treatment of the neurasthenia, and is dizzy forgetful, carbuncle, sore can also dispelling pathogenic wind and eliminating phlegm, counteracting toxic substances, detoxifcation.
Compatibility relationship of the present invention is: 1. monarch drug: Fructus Xanthii, and the rheumatism of loosing, clearing the nasal passage can be controlled headche due to wind-cold, the nasal sinusitis watery nasal discharge; Flos Magnoliae, it is cold to dispel the wind, and clearing the nasal passage can be controlled headache nasal sinusitis, and it is obstructed to have a stuffy nose; 2. ministerial drug: the Radix Angelicae Dahuricae, go into lung stomach warp, expelling pathogenic wind from the body surface, pain relieving, detumescence, headache is controlled in evacuation of pus, watery nasal discharge, nasal obstruction; Herba Menthae, dispelling wind-heat, the cleaning head controls anemopyretic cold, the headache conjunctival congestion; 3. adjuvant drug: Gypsum Fibrosum, heat clearing away, pathogenic fire purging, detoxifcation, collateral dredging is used to the lung of dispelling, stomach-fire; Herba Ephedrae is dispersed wind heat, is used for Pulvis Diaphoreticus wind; Herba Houttuyniae, the heat radiation detumescence, removing pathogenic heat from blood and toxic substance from the body is used for clearing away lung-heat, purte the white; Radix Salviae Miltiorrhizae, stasis-dispelling and pain-killing, blood-cooling and spirit-quieting is used for the eliminating carbuncle pain relieving, blood circulation promoting and blood stasis dispelling, tranquilizing by nourishing the heart; Radix Pseudostellariae, analgesic, antiinflammatory, antibiotic, antiviral is used for the treatment of weakness of the spleen and stomach, inappetence, neurasthenia; Spina Gleditsiae is invigorated blood circulation, and dispels the wind, draw out pus by applying a plaster to the affected part, and detumescence, evacuation of pus can be treated carbuncle, and the energy dispelling pathogenic wind and eliminating phlegm can detoxify; 4. messenger drug: Herba Alii fistulosi, the tying-in clearing the nasal passage can the through sick institute of the efficacy of a drug, and therapeutic effect is better.In sum, all medicines share, and add Herba Alii fistulosi and draw, and reach lung heat clearing jointly, and gastric heat is controlled nasal sinusitis, and clearing the nasal passage is controlled headache, antiviral, and the sharp head, the purpose of sinusitis is fundamentally treated in the refreshment of having one's ideas straightened out.
For further showing the therapeutic effect of medicine of the present invention, done following clinical verification:
The patient chooses:
Picked at random 600 routine patients in the sinusitis patient of hospital outpatient, according to sex, age, state of an illness weight hierarchical, each layer is divided into matched group, light disease treatment group at random then, serious symptom treatment group, every group 200 example, wherein the patient with slight symptoms is meant that the patient has headache, snivel, nasal obstruction, medical history is below 1 year; The patient with severe symptoms is meant that the patient has headache, flows turbid tears, nasal obstruction, and hypomnesis, medical history is more than 1 year.
Diagnostic criteria:
Formulate with reference to State Administration of Traditional Chinese Medicine's " disease of tcm diagnosis criterion of therapeutical effect ": 1. clinical recovery: be meant headache, nasal obstruction, recoveries from illness such as watery nasal discharge, memory is recovered, and violates so far; 2. clinical produce effects: be meant headache, nasal obstruction, recoveries from illness such as watery nasal discharge, hypermnesia, but flu casual offense; 3. clinical effectively: be finger not bitterly, idol has nasal obstruction, watery nasal discharge; 4. clinical invalid: be meant the headache headache, nasal obstruction, the symptom of watery nasal discharge there is no gently, and memory is relatively poor.
Therapeutic Method
Light disease treatment group: every dose get Fructus Xanthii 12 grams, Flos Magnoliae 12 grams, the Radix Angelicae Dahuricae 6 grams, Herba Asari 3 grams, Herba Menthae 6 grams, Gypsum Fibrosum 30 grams, band must one 30 gram of Herba Alii fistulosi, Herba Ephedrae 10 grams and Herba Houttuyniae 15 grams, dose fries in shallow oil twice, sooner or later services once, taking medicine after meal serve on 9 days;
Serious symptom treatment group: every dose get Fructus Xanthii 12 gram, Flos Magnoliae 12 grams, the Radix Angelicae Dahuricae 6 grams, Herba Asari 3 grams, Herba Menthae 6 grams, Gypsum Fibrosum 30 grams, band must one 30 gram of Herba Alii fistulosi, Herba Ephedrae 10 grams, Herba Houttuyniae 15 grams, Radix Salviae Miltiorrhizae 12 grams, Radix Pseudostellariae 15 grams and Spina Gleditsiae 10 grams, dose is fried in shallow oil twice, sooner or later service once, taking medicine after meal serve on 12 days to 15 days;
Matched group: give up scorching pin or defeated antibiotic medicine, once a day, continuous 15 days.
Therapeutic outcome
After around treatment group and matched group are treated respectively, the total effective rate of light disease treatment group is 100%, and the total effective rate of serious symptom treatment group is 97%, and the total effective rate of matched group is 60%, and concrete numerical value sees Table 1.
Table 1: light disease treatment group, serious symptom treatment group and matched group curative effect are relatively
Clinical observation shows: medicine of the present invention has the good clinical curative effect for the treatment sinusitis, can effectively treat sinusitis, and thoroughly effect a radical cure sinusitis, thereby improve patient's resistance, enhancing immunity, also clear-headed brains of patient and sensitive nose key are given work, and study brings happy greatly! Cost of the present invention in addition is low, instant effect, and short treating period has no side effect.
The specific embodiment
Embodiment 1
At light disease sinusitis patient, the medicine of present embodiment treatment sinusitis is that the medicine with following weight is a crude drug:
Fructus Xanthii 12 grams, Flos Magnoliae 12 grams, the Radix Angelicae Dahuricae 6 grams, Herba Asari 2 grams, Herba Menthae 6 grams, Gypsum Fibrosum 30 grams and band must Herba Alii fistulosi 30 grams.
Concrete preparation method is: get above-mentioned parts of medicines by weight in container, the water logging that adds 8 times was steeped 1.5 hours, fry in shallow oil to boiling with very hot oven, kept 20 minutes, pour out decocting liquid, in container, add 5 times water again, the reuse very hot oven is fried in shallow oil to boiling, keeps 15 minutes, pours out decocting liquid, merge decocting liquid twice, sterilization is made.
Instructions of taking: dose fries in shallow oil twice, sooner or later services once, and taking medicine after meal serve on 7 days.
Embodiment 2
At the snivel patient, the medicine of present embodiment treatment sinusitis is a crude drug with the medicine of following weight:
Fructus Xanthii 13 restrains, Flos Magnoliae 13 restrains, the Radix Angelicae Dahuricae 7 restrains, Herba Asari 3.5 restrains, Herba Menthae 7 restrains, Gypsum Fibrosum 35 restrains, is with palpus Herba Alii fistulosi 35 to restrain and Herba Ephedrae 10 restrains.
Concrete preparation method is: get above-mentioned parts of medicines by weight in container, the water logging that adds 7 times was steeped 1.5 hours, fry in shallow oil to boiling with very hot oven, kept 16 minutes, pour out decocting liquid, in container, add 4.7 times water again, the reuse very hot oven is fried in shallow oil to boiling, keeps 13 minutes, pours out decocting liquid, merge decocting liquid twice, sterilization is made.
Instructions of taking: dose fries in shallow oil twice, sooner or later services once, and taking medicine after meal serve on 7 days.
Embodiment 3
At stream turbid nasal discharge patient, the medicine of present embodiment treatment sinusitis is a crude drug with the medicine of following weight:
Fructus Xanthii 14 gram, Flos Magnoliae 14 grams, the Radix Angelicae Dahuricae 8 grams, Herba Asari 2.5 grams, Herba Menthae 8 grams, Gypsum Fibrosum 40 grams, band must Herba Alii fistulosi 40 grams, Herba Ephedrae 10 grams and Herba Houttuyniae 15 grams.
Concrete preparation method is: get above-mentioned parts of medicines by weight in container, the water logging that adds 7.5 times was steeped 1.3 hours, fry in shallow oil to boiling with very hot oven, kept 17 minutes, pour out decocting liquid, in container, add 4.5 times water again, the reuse very hot oven is fried in shallow oil to boiling, keeps 14 minutes, pours out decocting liquid, merge decocting liquid twice, sterilization is made.
Instructions of taking: dose fries in shallow oil twice, sooner or later services once, and taking medicine after meal serve on 9 days.
Embodiment 4
At the long patient of the course of disease, the medicine of present embodiment treatment sinusitis is a crude drug with the medicine of following weight:
Fructus Xanthii 15 gram, Flos Magnoliae 15 grams, the Radix Angelicae Dahuricae 9 grams, Herba Asari 2 grams, Herba Menthae 8 grams, Gypsum Fibrosum 45 grams, band must Herba Alii fistulosi 45 grams, Herba Houttuyniae 18 grams, Radix Salviae Miltiorrhizae 12 grams, Radix Pseudostellariae 15 grams and Spina Gleditsiae 10 grams.
Concrete preparation method is: get above-mentioned parts of medicines by weight in container, the water logging that adds 8 times was steeped 1.5 hours, fry in shallow oil to boiling with very hot oven, kept 20 minutes, pour out decocting liquid, in container, add 5 times water again, the reuse very hot oven is fried in shallow oil to boiling, keeps 15 minutes, pours out decocting liquid, merge decocting liquid twice, sterilization is made.
Instructions of taking: dose fries in shallow oil twice, sooner or later services once, and taking medicine after meal serve on 12 days.
Embodiment 5
At the empty patient of body, the medicine of present embodiment treatment sinusitis is a crude drug with the medicine of following weight:
Fructus Xanthii 13 restrains, Flos Magnoliae 15 restrains, the Radix Angelicae Dahuricae 8 restrains, Herba Asari 4 restrains, Herba Menthae 7 restrains, Gypsum Fibrosum 38 restrains, is with palpus Herba Alii fistulosi 42 to restrain and Radix Pseudostellariae 17 restrains.
Concrete preparation method is: get above-mentioned parts of medicines by weight in container, the water logging that adds 7 times was steeped 1.2 hours, fry in shallow oil to boiling with very hot oven, kept 18 minutes, pour out decocting liquid, in container, add 4.5 times water again, the reuse very hot oven is fried in shallow oil to boiling, keeps 12 minutes, pours out decocting liquid, merge decocting liquid twice, sterilization is made.
Instructions of taking: dose fries in shallow oil twice, sooner or later services once, and taking medicine after meal serve on 12 days.
Embodiment 6
At long patient of stream turbid nasal discharge, pus tears time, the medicine of present embodiment treatment sinusitis is a crude drug with the medicine of following weight:
Fructus Xanthii 15 gram, Flos Magnoliae 15 grams, the Radix Angelicae Dahuricae 7 grams, Herba Asari 3 grams, Herba Menthae 8 grams, Gypsum Fibrosum 40 grams, band must Herba Alii fistulosi 42 grams, Herba Ephedrae 12 grams, Herba Houttuyniae 20 grams, Radix Salviae Miltiorrhizae 15 grams, Radix Pseudostellariae 18 grams and Spina Gleditsiae 15 grams.
Concrete preparation method is: get above-mentioned parts of medicines by weight in container, the water logging that adds 6 times was steeped 1 hour, fry in shallow oil to boiling with very hot oven, kept 15 minutes, pour out decocting liquid, in container, add 4 times water again, the reuse very hot oven is fried in shallow oil to boiling, keeps 10 minutes, pours out decocting liquid, merge decocting liquid twice, sterilization is made.
Instructions of taking: dose fries in shallow oil twice, sooner or later services once, and taking medicine after meal serve on 15 days.
Claims (5)
1. medicine for the treatment of sinusitis is characterized in that with following parts of medicines by weight be crude drug:
30～45 parts of 12～15 parts of Fructus Xanthii, 12～15 parts of Flos Magnoliaes, 6～9 parts of the Radixs Angelicae Dahuricae, 2～4 parts of Herba Asaris, 6～8 parts of Herba Menthaes, 30～45 parts of Gypsum Fibrosum and Herba Alii fistulosis;
Wherein said Herba Alii fistulosi must Herba Alii fistulosi for band.
2. a kind of medicine for the treatment of sinusitis according to claim 1 is characterized in that also comprising in the following portions by weight crude drug one or more:
10～15 parts of 9～12 parts in Herba Ephedrae, 15～20 parts of Herba Houttuyniae, 12～15 parts of Radix Salviae Miltiorrhizaes, 15～18 parts of Radix Pseudostellariaes or Spina Gleditsiaes.
3. claim 1 or 2 described a kind of medicines for the treatment of sinusitis is characterized in that described medicine is a said dosage form on any pharmaceutics.
4. the described a kind of medicine for the treatment of sinusitis of claim 3 is characterized in that described medicine is a decoction.
5. the described a kind of preparation method for the treatment of the medicine of sinusitis of claim 4, it is characterized in that getting above-mentioned parts of medicines by weight in container, the water logging that adds 6～8 times was steeped 1～1.5 hour, fried in shallow oil to boiling with very hot oven, kept 15～20 minutes, pour out decocting liquid, add 4～5 times water again in container, the reuse very hot oven is fried in shallow oil to boiling, kept 10～15 minutes, pour out decocting liquid, merge decocting liquid twice, sterilization is made.
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| CN 201110222989 CN102274385B (en) | 2011-08-05 | 2011-08-05 | Medicament for treating nasosinusitis and preparation method thereof |
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| CN 201110222989 CN102274385B (en) | 2011-08-05 | 2011-08-05 | Medicament for treating nasosinusitis and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102614306A (en) * | 2012-04-18 | 2012-08-01 | 刘洪波 | Traditional Chinese herbal preparation for treating chronic nasosinusitis |
| CN103655878A (en) * | 2012-09-11 | 2014-03-26 | 陈云玺 | Medicine for curing acute and chronic nasosinusitis through anapnotherapy |
| CN105902645A (en) * | 2016-04-26 | 2016-08-31 | 于龙 | External-use ointment for treating rhinitis |
| CN106420926A (en) * | 2016-08-30 | 2017-02-22 | 李洪芳 | Traditional Chinese medicine for treating nasosinusitis and preparation method thereof |
| CN107334817A (en) * | 2017-06-30 | 2017-11-10 | 郑州澍青医学高等专科学校 | A kind of Chinese medicine for treating nasosinusitis |
-
2011
- 2011-08-05 CN CN 201110222989 patent/CN102274385B/en active Active
Non-Patent Citations (2)
| Title |
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| 《中医外治杂志》 19970531 秦雪梅等 《理瀹骈文》中的鼻药疗法 , 第5期 * |
| 《中华中医药学会耳鼻咽喉科分会第十二次学术研讨会暨嗓音言语听力医学专题学术研讨会论文集》 20051231 汤念翥 鼻以通为用 , * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102614306A (en) * | 2012-04-18 | 2012-08-01 | 刘洪波 | Traditional Chinese herbal preparation for treating chronic nasosinusitis |
| CN103655878A (en) * | 2012-09-11 | 2014-03-26 | 陈云玺 | Medicine for curing acute and chronic nasosinusitis through anapnotherapy |
| CN105902645A (en) * | 2016-04-26 | 2016-08-31 | 于龙 | External-use ointment for treating rhinitis |
| CN106420926A (en) * | 2016-08-30 | 2017-02-22 | 李洪芳 | Traditional Chinese medicine for treating nasosinusitis and preparation method thereof |
| CN107334817A (en) * | 2017-06-30 | 2017-11-10 | 郑州澍青医学高等专科学校 | A kind of Chinese medicine for treating nasosinusitis |
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| CN102274385B (en) | 2013-03-06 |
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