CN104524090A - Traditional Chinese medicine preparation for treating sequelae of head injury - Google Patents
Traditional Chinese medicine preparation for treating sequelae of head injury Download PDFInfo
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- CN104524090A CN104524090A CN201410819636.9A CN201410819636A CN104524090A CN 104524090 A CN104524090 A CN 104524090A CN 201410819636 A CN201410819636 A CN 201410819636A CN 104524090 A CN104524090 A CN 104524090A
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Abstract
The invention discloses a traditional Chinese medicine for treating sequelae of head injury. The preparation is prepared from the following medicinal raw materials in parts by weight: 20-30g of amber, 10-20g of fossilia dentis mastoid, 10-20g of radix paeoniae alba, 10-20g of caulis akebiae, 10-20g of rhizoma cyperi, 10-20g of semen brassicae, 10-20g of pseudo-ginseng, 10-20g of peach kernel, 10-20g of pericarpium arecae, 8-15g of schizonepeta spike, 8-12g of rhizoma drynariae, 8-12g of fructus viticis, 8-12g of safflower carthamus, 8-12g of antelope horn powder, 8-12g of scorpion, 8-15g of raw oyster, 8-15g of fried cape jasmine and 8-15g of codonopsis pilosula. The medicinal materials are excellent in combination and reasonable in prescription to play the effects of tonifying liver and kidney, benefiting qi for promoting production of fluid, soothing-liver, regulating qi, promoting blood circulation to remove stasis, clearing heat, eliminating dampness, calming and tranquilizing, has the advantages of exact curative effect, economy, practicality, no side effect, high cure rate, no relapse and the like when used for treating sequelae after head injury, and is worthy of clinical popularization and application.
Description
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation can treating head injury sequela.
Background technology
Head injury sequela, also known as postcerebral injury syndrome, is the most common a kind of sequela of after craniocerebral injury.This disease is had after about having the patient of 20% to hinder.The symptom of patient is varied, main have headache, dizzy, insomnia, dreaminess, attention can not be concentrated, forgetful, can not tolerate that noise, tinnitus, dim eyesight, paces are unstable, tired, unable, inappetence, personality changes, remain passive and pessimistic, depressed joyless, neck aches, often a people has multiple symptom.But take the photograph the aspect such as sheet, CT from physical examination, lumbar puncture, neurologic check and X-ray head, then visible without objective exception.
Current clinical treatment aspect generally adopts composite treatment, comprise various remedy measures, as the qigong, taijiquan, balance gymnastics, acupuncture, Intravenous Procaine injection, vein magnesium salt therapy, physical therapy, various sedation and analgesia agent for oral administration etc., but Western medicine long-term taking not only low effort, and easily recur, make protracted inflammation continuous, patient easily produces drug dependence, brings very large side effects to health.And the traditional Chinese medical science be usually particular about dialectically to treat, treating both the principal and secondary aspects of a disease, therefore we utilize multiple Chinese herbal medicine to mix fried Chinese medicine preparation treatment head injury sequela and achieve positive effect in recent years.
Summary of the invention
Instant invention overcomes the technical deficiency existed in treatment head injury sequela at present, provide a kind of determined curative effect, economical and practical, have no side effect, cure rate is high, the Chinese medicine preparation that not easily recurs.
The technical solution adopted in the present invention is: a kind of Chinese medicine preparation for the treatment of head injury sequela, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Succinum 20-30 gram, Dens Draconis 10-20 gram, Radix Paeoniae Alba 10-20 gram, Caulis Akebiae 10-20 gram, Rhizoma Cyperi 10-20 gram, Semen Sinapis Albae 10-20 gram, Radix Notoginseng 10-20 gram, Semen Persicae 10-20 gram, Pericarpium Arecae 10-20 gram, Herba Schizonepetae 8-15 gram, Rhizoma Drynariae 8-12 gram, Fructus Viticis 8-12 gram, Flos Carthami 8-12 gram, Cornu Saigae Tataricae powder 8-12 gram, Scorpio 8-12 gram, SHENGLONGMU 8-15 gram, Fructus Gardeniae (parched) 8-15 gram, Radix Codonopsis 8-15 gram.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Succinum 20 grams, Dens Draconis 10 grams, the Radix Paeoniae Alba 10 grams, Caulis Akebiae 10 grams, Rhizoma Cyperi 10 grams, Semen Sinapis Albae 10 grams, Radix Notoginseng 10 grams, 10 grams, Semen Persicae, Pericarpium Arecae 10 grams, Herba Schizonepetae 8 grams, Rhizoma Drynariae 8 grams, Fructus Viticis 8 grams, 8 grams, Flos Carthami, Cornu Saigae Tataricae powder 8 grams, Scorpio 8 grams, SHENGLONGMU 8 grams, Fructus Gardeniae (parched) 8 grams, Radix Codonopsis 8 grams.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Succinum 25 grams, Dens Draconis 15 grams, the Radix Paeoniae Alba 15 grams, Caulis Akebiae 15 grams, Rhizoma Cyperi 15 grams, Semen Sinapis Albae 15 grams, Radix Notoginseng 15 grams, 15 grams, Semen Persicae, Pericarpium Arecae 15 grams, Herba Schizonepetae 12 grams, Rhizoma Drynariae 10 grams, Fructus Viticis 10 grams, 10 grams, Flos Carthami, Cornu Saigae Tataricae powder 10 grams, Scorpio 10 grams, SHENGLONGMU 12 grams, Fructus Gardeniae (parched) 12 grams, Radix Codonopsis 12 grams.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Succinum 30 grams, Dens Draconis 20 grams, the Radix Paeoniae Alba 20 grams, Caulis Akebiae 20 grams, Rhizoma Cyperi 20 grams, Semen Sinapis Albae 20 grams, Radix Notoginseng 20 grams, 20 grams, Semen Persicae, Pericarpium Arecae 20 grams, Herba Schizonepetae 15 grams, Rhizoma Drynariae 12 grams, Fructus Viticis 12 grams, 12 grams, Flos Carthami, Cornu Saigae Tataricae powder 12 grams, Scorpio 12 grams, SHENGLONGMU 15 grams, Fructus Gardeniae (parched) 15 grams, Radix Codonopsis 15 grams.
The instructions of taking of above-mentioned Chinese medicine preparation is: after being mixed by the raw material Chinese medicine of above-mentioned weight proportion, traditionally the method for fried Chinese medicine gets its medicine juice, every day 1 dose, adds clear water 400ml, soaks 30 minutes, first boils rear taking liquid 150ml at a simmer with high heat; Take medicinal liquid 150ml again.By 2 liquid medicine mixings, point morning, late 2 decoction being taken warmly.Every day 1 dose 30 days is 1 course for the treatment of.
The raw material Chinese medicine of above-mentioned Chinese medicine preparation:
Succinum, sweet in the mouth, property are flat; GUIXIN, liver, small intestinal, bladder, lung, spleen channel.Have tranquillizing the mind by relieving convulsion, dissipating blood stasis stops blooding, relieving stranguria by diuresis, effect of removing nebula improving eyesight.
Dens Draconis, sweet in the mouth, puckery, property is put down; GUIXIN, liver, kidney channel.There is tranquillizing the mind by relieving convulsion, suppressing the hyperactive liver and subsiding YANG, restrain astringent or styptic treatment for spontaneous sweating effect.
The Radix Paeoniae Alba, bitter in the mouth, acid, cold nature; Return Liver Channel.There is the yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, effect of suppressing the hyperactive liver and subsiding YANG.
Caulis Akebiae, bitter in the mouth, cold in nature; GUIXIN, small intestinal, urinary bladder channel.There is relieving stranguria by diuresis, the effect of the stimulating milk secretion that expels the heat-evil.
Rhizoma Cyperi, acrid in the mouth, micro-hardship, micro-sweet, property is put down; Return liver, tri-jiao channel.There is depressed liver-energy dispersing and QI regulating, effect of menstruction regulating and pain relieving.
Semen Sinapis Albae, acrid in the mouth, warm in nature; Return lung meridian.There is warming the lung to eliminate phlegm, promoting the circulation of QI eliminating stagnation, effect of removing obstruction in the collateral to relieve pain.
Radix Notoginseng, sweet in the mouth, micro-hardship, warm in nature; GUIXIN, liver, spleen channel.There is removing stasis to stop bleeding, effect of reducing swelling and alleviating pain.
Semen Persicae, sweet in the mouth, hardship, property is put down; Return lung, liver, large intestine channel.There is blood circulation promoting and blood stasis dispelling, moisturize effect of laxation.
Pericarpium Arecae, acrid in the mouth, warm in nature; Return spleen, stomach, large intestine, small intestine meridian.There is regulating the flow of QI to ease the stomach, effect of inducing diuresis to remove edema.
Herba Schizonepetae, acrid in the mouth, slightly warm in nature; Return lung, Liver Channel.There is the loose wind that induces sweat, effect of rash.
Rhizoma Drynariae, bitter in the mouth, warm in nature; Return liver, kidney channel.There is the kidney invigorating bone strengthening, blood circulation promoting and blood stasis dispelling, the effect of pain relieving of curing the wound.
Fructus Viticis, acrid in the mouth, hardship, cold nature; Return bladder, liver, stomach warp.There is dispelling wind and heat pathogens, the clear sharp head, effect of pain relieving.
Flos Carthami, acrid in the mouth, warm in nature; GUIXIN, Liver Channel.There is promoting blood circulation to restore menstrual flow, effect of eliminating stasis to stop pain.
Cornu Saigae Tataricae powder, salty in the mouth, cold in nature; Return liver, heart channel.There is clearing away heat and relieving spasm, suppressing the hyperactive liver to relieve the wind syndrome, effect of removing toxic substances and promoting subsidence of swelling.
Scorpio, acrid in the mouth, property is put down; Return Liver Channel.There is relieving spasm by subduing liver-wind, detoxicating and resolving stagnation of pathogens, effect of removing obstruction in the collateral to relieve pain.
SHENGLONGMU, sweet in the mouth, salty, property is put down; Return Liver Channel.There is YIN nourishing benefit blood, effect of removing damp-heat.
Fructus Gardeniae (parched), bitter in the mouth, cold in nature.GUIXIN, lung, stomach, tri-jiao channel.There is clearing away heat and promoting diuresis, effect of dispel fiery relieving restlessness, removing pathogenic heat from blood and toxic substance from the body.
Radix Codonopsis, sweet in the mouth, property is put down; Return spleen, lung meridian.There is invigorating the spleen and replenishing QI, effect nourished blood of promoting the production of body fluid.
Chinese medicine is thought, the collision of head injury sequela system wound, and venation stops up resistance, and QI-blood circulation is smooth, and caused by brain is lost and supported, therefore treatment is when with warm venting QI-blood, and brain-strengthening is allayed excitement as principle.
In Chinese medicine preparation of the present invention, succinum, Dens Draconis can tranquillizing and allaying excitement, restrain astringent or styptic treatment for spontaneous sweating, have calm analgesic activity; The Radix Paeoniae Alba, Rhizoma Cyperi, Cornu Saigae Tataricae powder energy depressed liver-energy dispersing and QI regulating, suppressing the hyperactive liver and subsiding YANG, availablely gives excessive rising of liver-YANG, the vertigo, and liver-wind stirring up internally, the slight illness such as infantile convulsion tic; Rhizoma Drynariae, Radix Codonopsis, SHENGLONGMU can YIN nourishing benefit blood, the kidney invigorating bone strengthening, conditioning viscera, improve immunity of organisms; Caulis Akebiae, Fructus Gardeniae (parched), Semen Sinapis Albae, Pericarpium Arecae can relieving stranguria by diuresis, dispersing swelling and dissipating binds, fiery relieving restlessness of dispelling, removing pathogenic heat from blood and toxic substance from the body; Radix Notoginseng, Semen Persicae, Flos Carthami energy promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, promotion of blood circulation, promotes blood microcirculation; Herba Schizonepetae, Fructus Viticis, Scorpio energy relieving spasm by subduing liver-wind, dispelling wind and heat pathogens, the clear sharp head, removing obstruction in the collateral to relieve pain, effectively dispels toxic dampness and heat in body, with strengthening the body resistance.All medicine compatibilities are superior, and reasonable recipe, plays the liver and the kidney tonifying altogether, supplementing QI for promoting the production of body fluid, depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling, clearing heat and expelling damp, calm effect of allaying excitement, medicine can effectively hit head injury sequela pathogenesis, improve the operation of governor vessel QI and blood, expand cerebral vessels, improve brain blood circulation, promote resuming function of brain cell, refreshment of having one's ideas straightened out, reduce and eliminate brain injury sequela, improving life in patients.
For investigating clinical efficacy and the safety of medicine of the present invention further, we have selected 158 routine out-patients and carry out clinical trial, wherein man 96 example, female 62 example, age 11-68 year, 42.5 years old mean age.All patients all have following characteristics: 1, closed injury of brain medical history; 2, have or without stupor history; 3, distending pain in the head; 4, dizzy; 5, insomnia and dreamful sleep; 6, to noise-sensitive; 7, hypomnesis; 8, ergasia weakens; 9, head CT, MRI checks normal.All patients are divided into treatment group and matched group at random.Age of two groups of patients, sex, course of disease isobase data are through statistical analysis, and no significant difference (P > 0.05), has comparability.
Observation index: two groups of patients over the course for the treatment of, all to common dizziness, headache, insomnia and dreamful sleep, to noise-sensitive, irritated fatiguability, memory weakens, activity weakens etc., and clinical symptoms is observed.
Therapeutic Method:
Treatment group takes Chinese medicine preparation of the present invention, get succinum 25 grams, Dens Draconis 15 grams, the Radix Paeoniae Alba 15 grams, Caulis Akebiae 15 grams, Rhizoma Cyperi 15 grams, Semen Sinapis Albae 15 grams, Radix Notoginseng 15 grams, 15 grams, Semen Persicae, Pericarpium Arecae 15 grams, Herba Schizonepetae 12 grams, Rhizoma Drynariae 10 grams, Fructus Viticis 10 grams, 10 grams, Flos Carthami, Cornu Saigae Tataricae powder 10 grams, Scorpio 10 grams, SHENGLONGMU 12 grams, Fructus Gardeniae (parched) 12 grams, Radix Codonopsis 12 grams (with disease plus-minus), after getting its medicine juice by above-mentioned decocting method, point morning, late 2 decoction being taken warmly.Every day 1 dose 30 days is 1 course for the treatment of.The oral Jiannao Tablet of matched group (Jilin Jichun Pharmaceutical Co., Ltd. produces, the accurate word Z20060242 of traditional Chinese medicines).One time 2,3 times on the one.To keep quite as far as possible in two groups of patient treatment procedure environment, lie up more, actively carry out the measures such as some psychotherapys simultaneously.
Efficacy result:
1. Clinical efficacy comparison
After two groups of patients all treat 1 course for the treatment of, improve situation to clinical 7 kinds of common brain injury sequela symptoms and compare, treatment group effective percentage is apparently higher than matched group, and two groups of differences have significance (P < 0.05).Detailed results is in table 1.
Table 1: improve situation comparison sheet before and after two groups of main clinic symptoms treatments
2 bad should be compared:
Two groups of patients all do not find obvious adverse reaction in the treatment.
Result shows, Chinese medicine preparation treatment head injury sequela curative effect of the present invention is obviously better than conventional medication, have instant effect, short treating period, economical and practical, have no side effect, the advantage such as cure rate is high, can not only effectively improve or cure the various clinical symptoms such as dizziness, headache, insomnia and dreamful sleep, neurosal generation after can also effectively preventing brain wound, clinic promotion and application.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation for the treatment of head injury sequela, chooses succinum 20 grams, Dens Draconis 10 grams, the Radix Paeoniae Alba 10 grams, Caulis Akebiae 10 grams, Rhizoma Cyperi 10 grams, Semen Sinapis Albae 10 grams, Radix Notoginseng 10 grams, 10 grams, Semen Persicae, Pericarpium Arecae 10 grams, Herba Schizonepetae 8 grams, Rhizoma Drynariae 8 grams, Fructus Viticis 8 grams, 8 grams, Flos Carthami, Cornu Saigae Tataricae powder 8 grams, Scorpio 8 grams, SHENGLONGMU 8 grams, Fructus Gardeniae (parched) 8 grams, Radix Codonopsis 8 grams.
Embodiment 2: a kind of Chinese medicine preparation for the treatment of head injury sequela, chooses succinum 25 grams, Dens Draconis 15 grams, the Radix Paeoniae Alba 15 grams, Caulis Akebiae 15 grams, Rhizoma Cyperi 15 grams, Semen Sinapis Albae 15 grams, Radix Notoginseng 15 grams, 15 grams, Semen Persicae, Pericarpium Arecae 15 grams, Herba Schizonepetae 12 grams, Rhizoma Drynariae 10 grams, Fructus Viticis 10 grams, 10 grams, Flos Carthami, Cornu Saigae Tataricae powder 10 grams, Scorpio 10 grams, SHENGLONGMU 12 grams, Fructus Gardeniae (parched) 12 grams, Radix Codonopsis 12 grams.
Embodiment 3: a kind of Chinese medicine preparation for the treatment of head injury sequela, chooses succinum 30 grams, Dens Draconis 20 grams, the Radix Paeoniae Alba 20 grams, Caulis Akebiae 20 grams, Rhizoma Cyperi 20 grams, Semen Sinapis Albae 20 grams, Radix Notoginseng 20 grams, 20 grams, Semen Persicae, Pericarpium Arecae 20 grams, Herba Schizonepetae 15 grams, Rhizoma Drynariae 12 grams, Fructus Viticis 12 grams, 12 grams, Flos Carthami, Cornu Saigae Tataricae powder 12 grams, Scorpio 12 grams, SHENGLONGMU 15 grams, Fructus Gardeniae (parched) 15 grams, Radix Codonopsis 15 grams.
Below by concrete case, Chinese medicine preparation curative effect of the present invention is verified further:
Case 1
Grandson, man, 42 years old.Patient, the year before because of the head injuries that gets into an accident, through often feeling dizziness, headache, head fiber crops after physical rehabilitation, realizes slightly fuzzy, grogginess.Feel that whole head is infinitely great, speak image distance face-to-face from far with people, examination in hospital is diagnosed as head injury sequela.Once took pyritionol hydrochloride neuroxin, the spirit of health brain, cerebrolysin assisted vitamin B to treat, but DeGrain.So under friend recommendation, start to take Drug therapy of the present invention, medication is after 1 week, and the symptoms such as the conscious dizziness headache of patient alleviate to some extent, sleep improvement, and after continuing 1 course for the treatment of of medication, all diseases disappear, and patient recovers orthobiosis, follows up a case by regular visits to and has no recurrence half a year.
Case 2
Yu, female, 35 years old.Patient's 2 years causes are fallen from eminence and are encountered head, hospitalize starts to occur headache, dizzy, insomnia and dreamful sleep without obvious inducement after being discharged from hospitals upon recovery, chores cannot be concentrated, the weak symptom such as weak, the aspect such as sheet, CT is taken the photograph from physical examination, lumbar puncture, neurologic check and X-ray head, then visible without objective exception, be diagnosed as head injury sequela.So start to take medicine of the present invention upon somebody's introduction to treat, take medicine 2 weeks, the above symptom of patient is obviously improved, and sleep is good, and the mental status recovers better.Continue medication 2 weeks in addition after after treatment, all diseases of patient all disappear, and recover orthobiosis.Follow up a case by regular visits to and have no a recurrence in.
Claims (4)
1. treat a Chinese medicine preparation for head injury sequela, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Succinum 20-30 gram, Dens Draconis 10-20 gram, Radix Paeoniae Alba 10-20 gram, Caulis Akebiae 10-20 gram, Rhizoma Cyperi 10-20 gram, Semen Sinapis Albae 10-20 gram, Radix Notoginseng 10-20 gram, Semen Persicae 10-20 gram, Pericarpium Arecae 10-20 gram, Herba Schizonepetae 8-15 gram, Rhizoma Drynariae 8-12 gram, Fructus Viticis 8-12 gram, Flos Carthami 8-12 gram, Cornu Saigae Tataricae powder 8-12 gram, Scorpio 8-12 gram, SHENGLONGMU 8-15 gram, Fructus Gardeniae (parched) 8-15 gram, Radix Codonopsis 8-15 gram.
2. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Succinum 20 grams, Dens Draconis 10 grams, the Radix Paeoniae Alba 10 grams, Caulis Akebiae 10 grams, Rhizoma Cyperi 10 grams, Semen Sinapis Albae 10 grams, Radix Notoginseng 10 grams, 10 grams, Semen Persicae, Pericarpium Arecae 10 grams, Herba Schizonepetae 8 grams, Rhizoma Drynariae 8 grams, Fructus Viticis 8 grams, 8 grams, Flos Carthami, Cornu Saigae Tataricae powder 8 grams, Scorpio 8 grams, SHENGLONGMU 8 grams, Fructus Gardeniae (parched) 8 grams, Radix Codonopsis 8 grams.
3. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Succinum 25 grams, Dens Draconis 15 grams, the Radix Paeoniae Alba 15 grams, Caulis Akebiae 15 grams, Rhizoma Cyperi 15 grams, Semen Sinapis Albae 15 grams, Radix Notoginseng 15 grams, 15 grams, Semen Persicae, Pericarpium Arecae 15 grams, Herba Schizonepetae 12 grams, Rhizoma Drynariae 10 grams, Fructus Viticis 10 grams, 10 grams, Flos Carthami, Cornu Saigae Tataricae powder 10 grams, Scorpio 10 grams, SHENGLONGMU 12 grams, Fructus Gardeniae (parched) 12 grams, Radix Codonopsis 12 grams.
4. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Succinum 30 grams, Dens Draconis 20 grams, the Radix Paeoniae Alba 20 grams, Caulis Akebiae 20 grams, Rhizoma Cyperi 20 grams, Semen Sinapis Albae 20 grams, Radix Notoginseng 20 grams, 20 grams, Semen Persicae, Pericarpium Arecae 20 grams, Herba Schizonepetae 15 grams, Rhizoma Drynariae 12 grams, Fructus Viticis 12 grams, 12 grams, Flos Carthami, Cornu Saigae Tataricae powder 12 grams, Scorpio 12 grams, SHENGLONGMU 15 grams, Fructus Gardeniae (parched) 15 grams, Radix Codonopsis 15 grams.
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