CN102580004B - Chinese medicinal composition for treating male erectile dysfunction - Google Patents
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Abstract
The invention relates to a Chinese medicinal composition for treating male erectile dysfunction. Traditional Chinese medicine considers that male erectile dysfunction is caused by reasons, stagnation of qi due to depression of liver, liver and gallbladder damp-heat, renal injury due to panic, fire excess from yin deficiency, heart-spleen deficiency and the like. Therefore, according to the Chinese medicinal composition, Chinese medicines of common macrocarpium fruit, Chinese magnoliavine fruit, dried longan pulp, malaytea scurfpea fruit, walnut kernel, Chinese chive seed, szechwan tangshen root, suberect spatholobus stem, turmeric root-tuber, sword jackbean seed, rose and green tangerine peel which have the effects of soothing liver, resolving depression, invigorating spleen, supplementing qi, tonifying kidney and replenishing vital essence are decocted to form decoction, and honey is added to obtain decoction. By clinical experiments, the total effective rate is 93.9 percent, and compared with the grade of an erection function of a treatment group before treatment, the grade of the erection function of a treatment group after treatment is increased obviously, so the Chinese medicinal composition is worthy of popularization and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation for the treatment of male erectile dysfunction.
Background technology
Male erectile dysfunction (ED) refers to that the male continues or takes place repeatedly can not reach or keep to erect to finish, and can show as that to obtain the ability of erecing inconsistent, only can keep the trend of of short duration erection or anorthosis fully.ED is the modal a kind of functional disorder of male.In male crowd, the ED sickness rate raises with advancing age.According to authoritative institution's statistics, below 55 years old is 18.6%-75% more than 7%, 60 years old.The ED cause of disease mainly is divided into heart source property and organic two big classes.Organic ED comprises the incretion of nerve, vascular.The ED that in the past generally believed 86-90% is mental maladjustment.Yet human sexual activity relates to the complex physical process of a lot of aspects, and psychological and organic factor interaction influences each other often.Tcm treatment according to syndrome differentiation can be taken into account psychological and organic factor, to reach desired therapeutic effect.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of male erectile dysfunction.Chinese medicine thinks that male erectile dysfunction is many by due to the reasons such as stagnation of QI due to depression of the liver, dampness-heat in the liver and gallbladder, fear impairing kidney, hyperactivity of fire caused by deficiency of YIN, deficiency of both the heart and spleen.Be the rule for the treatment of with dispersing the stagnated live-QI to relieve the stagnation of QI, invigorating the spleen and benefiting QI, the kidney invigorating and essence nourishing.
The objective of the invention is to be achieved through the following technical solutions, the Chinese medicine composition of this treatment male erectile dysfunction is made by following parts by weight of Chinese traditional medicine: Fructus Corni 20-30 part, Fructus Schisandrae Chinensis 25-35 part, Arillus Longan 15-25 part, Fructus Psoraleae 20-30 part, Semen Juglandis 10-20 part, Folium Allii tuberosi seed 25-35 part, Radix Codonopsis 15-25 part, Caulis Spatholobi 10-15 part, Radix Curcumae 10-20 part, Semen Canavaliae 10-20 part, Flos Rosae Rugosae 9-13 part, Pericarpium Citri Reticulatae Viride 8-12 part, Mel 10-20 part.
Preferably, the Chinese medicine composition of this treatment male erectile dysfunction is made by following parts by weight of Chinese traditional medicine: 25 parts of Fructus Corni, 30 parts of Fructus Schisandrae Chinensis, 20 parts of Arillus Longans, 25 parts of Fructus Psoraleaes, 15 parts of Semen Juglandis, 30 parts of Folium Allii tuberosi seeds, 20 parts of Radix Codonopsis, 13 parts of Caulis Spatholobis, 15 parts of Radix Curcumaes, 15 parts of Semen Canavaliaes, 11 parts of Flos Rosae Rugosaes, 10 parts on Pericarpium Citri Reticulatae Viride, 15 parts of Mel.
Above-mentioned Chinese medicine decocting except Mel is become juice, add Mel again, make decoction, take for the patient.
In the side: the Fructus Corni liver and kidney tonifying, essence astringing and desertion stemming is used for soreness of waist and knee joint, impotence and seminal emission; The Fructus Schisandrae Chinensis convergence is astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming; The Arillus Longan invigorating the heart and spleen, nourishing blood to tranquillize the mind; Fructus Psoraleae: reinforcing the kidney and supporting YANG, helping inspiration to relieve asthma, warming spleen and stopping diarrha.Cure mainly insufficiency of kidney-YANG, below element deficiency and cold, chills and pain of the waist and kness, impotence and seminal emission; Semen Juglandis the kidney invigorating warming the lung, loosening bowel to relieve constipation; Folium Allii tuberosi seed temperature compensation Liver and kidney, tonifying YANG controlling nocturnal emission with astringent drugs, warm waist knee joint; The Radix Codonopsis invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting; Caulis Spatholobi is enriched blood and invigorates blood circulation, channels sootheing and network vessel quickening; The Radix Curcumae regulating qi to disperse stagnation, heart fire-clearing upset-relieving; The Semen Canavaliae warming the kidney to activate YANG, beneficial invigorating primordial QI; The Flos Rosae Rugosae promoting QI circulation for relieving depression, regulating blood flow to alleviate pains; Pericarpium Citri Reticulatae Viride depressed liver-energy dispersing and QI regulating, removing food stagnancyization stagnate; Mel improves cardiovascular function, hepatoprotective kidney tonifying, coordinating the actions of various ingredients in a prescription.
Clinical data
1, physical data 196 routine ED patients all from June, 2008 to 2009 year the court's outpatient service in October, adopt random packet, and wherein 98 examples are organized in treatment, matched group 98 examples; Wherein treatment group age 23-62 year, average (37.5 ± 9.8) year; The course of disease 3 months-10 days, average (2.3 ± 1.4) sky.Matched group age 24-61 year, average (36.8 ± 9.6) year; The course of disease 3 months-6 days, average (2.2 ± 1.5) sky.Two groups of aspects such as patient age, the course of disease, erection function integration and state of an illness weight more all do not have significant difference (P＞0.05), have comparability.
2, diagnostic criteria is with reference to international ED diagnosis principle, be the man under sexual stimulus, the erection that reaches or keep enough hardness that constantly continues is finishing satisfied sexual intercourse, and the course of disease is more than 3 months, international erection function scoring questionnaire (IIEF-5)≤21 minute is diagnosed as ED.
3, exclusion standard (1) complication with diabetes person; (2) be associated with disease patients such as the serious heart, liver, kidney, hemopoietic system; (3) prostate obviously increases survivor or prostatitis specific antigen (PSA)＞4ug/ml person; (4) psychotic; (5) took other related drugs person in the recent period; (6) medication or data are incomplete in accordance with regulations, can not adhere to normal therapeutic person.
4, treatment and observational technique treatment group are taken Chinese medicine composition of the present invention, namely get Fructus Corni 25g, Fructus Schisandrae Chinensis 30g, Arillus Longan 20g, Fructus Psoraleae 25g, Semen Juglandis 15g, Folium Allii tuberosi seed 30g, Radix Codonopsis 20g, Caulis Spatholobi 13g, Radix Curcumae 15g, Semen Canavaliae 15g, Flos Rosae Rugosae 11g, Pericarpium Citri Reticulatae Viride 10g decocting becomes soup, add Mel 15g again and make decoction, every day, potion divided secondary to take.Matched group is taken LIUWEI DIHUANG WAN, and 8/time, 3 times on the 1st; All treated for 8 weeks for 2 groups.Before the treatment, 4 weeks for the treatment of, treatment observe international questionnaire (IIEF-5) integration of erection function 8 weeks respectively and change, comprise erection confidence, successfully insert number of times, erection hardness, keep erectile ability and 5 problems of sexual intercourse satisfaction.
Statistical method adopts the SPSS11.0 statistical software to carry out data analysis, and (x ± s) expression adopts the t check to determination data with mean standard deviation.
5, criterion of therapeutical effect clinic control: treatment back sexual intercourse chance reaches 75% or more successfully, or erection function integration 〉=21 minute; Produce effects: treatment back sexual intercourse chance reaches success more than 50%, or the more preceding increase of erection function integration 7-14 branch; Effectively: treatment back sexual intercourse chance reaches success more than 25%, or the more preceding increase of erection function integration≤7 minutes; Invalid: treatment back sexual intercourse chance success rate no change, or the erection function integration does not have increase.
6, therapeutic outcome
All treat 8 all backs statistics curative effects for (1) two group.Two groups of curative effects relatively see Table 1.
Table 1 liang group curative effect is { (example) %} relatively
Annotate: two groups of curative effects relatively have significant difference (P＜0.05)
Erection function scoring change situation sees Table 2 before and after (2) two groups of treatments.The treatment group significantly increased before erection function scoring and the treatment (P＜0.01) in 4 weeks for the treatment of, 8 weeks; Treatment back treatment group and the scoring of matched group erection function have significant difference (P＜0.05).
An erection function scoring integration changes relatively (x ± s) before and after the treatment of table 2 liang group
The specific embodiment
Embodiment one: take by weighing Fructus Corni 25g, Fructus Schisandrae Chinensis 30g, Arillus Longan 20g, Fructus Psoraleae 25g, Semen Juglandis 15g, Folium Allii tuberosi seed 30g, Radix Codonopsis 20g, Caulis Spatholobi 13g, Radix Curcumae 15g, Semen Canavaliae 15g, Flos Rosae Rugosae 11g, Pericarpium Citri Reticulatae Viride 10g decocting becomes soup, add Mel 15g again and make decoction, every day, potion divided secondary to take.
Embodiment two: take by weighing Fructus Corni 20g, Fructus Schisandrae Chinensis 35g, Arillus Longan 15g, Fructus Psoraleae 30g, Semen Juglandis 10g, Folium Allii tuberosi seed 35g, Radix Codonopsis 15g, Caulis Spatholobi 15g, Radix Curcumae 10g, Semen Canavaliae 20g, Flos Rosae Rugosae 9g, Pericarpium Citri Reticulatae Viride 12g decocting becomes soup, add Mel 10g again and make decoction, every day, potion divided secondary to take.
Embodiment three: take by weighing Fructus Corni 30g, Fructus Schisandrae Chinensis 25g, Arillus Longan 25g, Fructus Psoraleae 20g, Semen Juglandis 20g, Folium Allii tuberosi seed 25g, Radix Codonopsis 25g, Caulis Spatholobi 10g, Radix Curcumae 20g, Semen Canavaliae 10g, Flos Rosae Rugosae 13g, Pericarpium Citri Reticulatae Viride 8g decocting becomes soup, add Mel 20g again and make decoction, every day, potion divided secondary to take.
Claims (1)
1. Chinese medicine composition for the treatment of male erectile dysfunction is characterized in that this Chinese medicine composition made by the Chinese medicine of following weight: Fructus Corni 25g, Fructus Schisandrae Chinensis 30g, Arillus Longan 20g, Fructus Psoraleae 25g, Semen Juglandis 15g, Folium Allii tuberosi seed 30g, Radix Codonopsis 20g, Caulis Spatholobi 13g, Radix Curcumae 15g, Semen Canavaliae 15g, Flos Rosae Rugosae 11g, Pericarpium Citri Reticulatae Viride 10g, Mel 15g.
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| CN 201210078911 CN102580004B (en) | 2012-03-14 | 2012-03-14 | Chinese medicinal composition for treating male erectile dysfunction |
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| CN 201210078911 CN102580004B (en) | 2012-03-14 | 2012-03-14 | Chinese medicinal composition for treating male erectile dysfunction |
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| CN102580004B true CN102580004B (en) | 2013-09-04 |
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| CN113368168B (en) * | 2021-07-28 | 2022-05-17 | 上海中医药大学附属龙华医院 | External liquid preparation for treating male erectile dysfunction and preparation method thereof |
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| CN1108132A (en) * | 1995-01-18 | 1995-09-13 | 江苏省中谊科技公司 | Health-care medicinal liquor and its prepn. method |
| CN100348263C (en) * | 2005-04-28 | 2007-11-14 | 陈宏棕 | Chinese medicine preparation for treating male sterility |
| CN101757528A (en) * | 2009-10-27 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composition for treating symptoms of deficiency of kidney yin and soreness and weakness of waist and knees and preparation method thereof |
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