CN103705641A - Traditional Chinese medicine composition for treating oligospermia and asthenozoospermia - Google Patents
Traditional Chinese medicine composition for treating oligospermia and asthenozoospermia Download PDFInfo
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- CN103705641A CN103705641A CN201410008849.3A CN201410008849A CN103705641A CN 103705641 A CN103705641 A CN 103705641A CN 201410008849 A CN201410008849 A CN 201410008849A CN 103705641 A CN103705641 A CN 103705641A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating oligospermia and asthenozoospermia. The composition is prepared from the following traditional Chinese raw materials in parts by weight: 10-30 parts of medlar, 5-25 parts of semen cuscutae, 5-25 parts of raspberries, 5-20 parts of schisandra chinensis, 5-20 parts of semen plantaginis, 5-20 parts of mulberry fruits, 5-25 parts of angelica sinensis, 5-20 parts of radix rehmanniae preparata, 10-30 parts of polygonum multiflorum, 10-30 parts of codonopsis pilosula, 10-30 parts of astragalus membranaceus, 5-25 parts of herba epimedii, 5-25 parts of dipsacus roots, 5-20 parts of pericarpium citri reticulatae and 5-15 parts of liquorice. The traditional Chinese medicine composition provided by the invention has the functions of nourishing liver and kidney, boosting essence and tonifying marrow, replenishing qi and enriching the blood and promoting blood circulation to remove blood stasis, and is remarkable in curative effect on oligospermia and asthenozoospermia treatment and reliable in effect.
Description
Technical field
The present invention relates to a kind of not pharmaceutical product of definite structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of few essence, azoospermia.
Background technology
Few essence, azoospermia are the comparatively common diseases of andrology, are also one of modal reasons of male infertility.In recent years, due to day by day the increasing the weight of of environmental pollution, sexually transmitted disease (STD) spread and the Occupational Exposure of harmful substance and bad living habit etc. affect male reproductive health, male semen quality is on a declining curve, makes the incidence rate of male sterility have increase trend.Few essence, azoospermia cause of disease complexity, doctor trained in Western medicine it is generally acknowledged, it is mainly to be caused by hereditary, congenital dysplasia, endocrine factors, obstruction of vas deferen, smart arteries and veins varicose, reproductive tract infection, immune factor, metabolic nutrition factor, medicine factor, diet, environmental factors, bad life habits etc.The few essence of western medical treatment, azoospermia, be mainly to adopt various hormone therapies for the cause of disease at present, though there is certain curative effect, have side effect in various degree, and clinical efficacy is not good enough, and patient is often difficult to accept.
The traditional Chinese medical science thinks that few essence, azoospermia belong to the category of the traditional Chinese medical science " oligospermia ", " essence rare ", " cold sperm ", many by deficiency of kidney essence, deficiency of qi and blood clinically, and blood-stasis internal-depression, due to damp invasion of lower energizer.
According to theory of Chinese medical science, for the pathogeny of few essence, azoospermia, the method for the treatment of that adopts nourishing the liver and kidney, spermatogenesis to mend marrow, carries out dialectical prescription compatibility, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
The deficiency existing in order to overcome in prior art the few essence for the treatment of, azoospermia, the invention provides a kind of prepare easy, cost is low, the Chinese medicine composition of the few essence for the treatment of evident in efficacy, that have no side effect, azoospermia.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of few essence, azoospermia, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Fructus Lycii 10-30 part, Semen Cuscutae 5-25 part, Fructus Rubi 5-25 part, Fructus Schisandrae Chinensis 5-20 part, Semen Plantaginis 5-20 part, Fructus Mori 5-20 part, Radix Angelicae Sinensis 5-25 part, Radix Rehmanniae Preparata 5-20 part, Radix Polygoni Multiflori 10-30 part, Radix Codonopsis 10-30 part, Radix Astragali 10-30 part, Herba Epimedii 5-25 part, Radix Dipsaci 5-25 part, Pericarpium Citri Reticulatae 5-20 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of few essence, azoospermia, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 20 parts of Fructus Lyciis, 15 parts of Semen Cuscutae, 15 parts of Fructus Rubies, 10 parts of Fructus Schisandrae Chinensis, 12 parts of Semen Plantaginiss, 10 parts of Fructus Mori, 15 parts of Radix Angelicae Sinensis, 12 parts, Radix Rehmanniae Preparata, 20 parts of Radix Polygoni Multiflori, 20 parts of Radix Codonopsis, 20 parts of the Radixs Astragali, 15 parts of Herba Epimedii, 15 parts of Radix Dipsaci, 10 parts of Pericarpium Citri Reticulataes, 6 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: Fructus Lycii has the effect of nourishing the liver and kidney, nourishing the liver to improve visual acuity, strengthening the body resistance, spermatogenesis benefit marrow, enriching yin and nourishing kidney, benefiting vital QI for tranquillizing; Semen Cuscutae has the effect of the kidney invigorating and essence nourishing, nourishing the liver spleen invigorating; Fructus Rubi has the effect of the liver and the kidney tonifying, controlling nocturnal emission with astringent drugs reducing urination, supporing yang improving eyesight; Fructus Schisandrae Chinensis has the effect of astringent or styptic treatment for spontaneous sweating, the supplementing QI for promoting the production of body fluid of convergence, kidney calming; Semen Plantaginis has the effect of relieving stranguria by diuresis, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, removing heat-phlegm; Fructus Mori has nourishing YIN and supplementing blood, the effect of the intestine moistening of promoting the production of body fluid; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation; Radix Rehmanniae Preparata has the effect of the yin nourishing of enriching blood, life essence-filling, marrow-benefitting; Radix Polygoni Multiflori has the effect of the liver benefiting that nourishes blood, controlling nocturnal emission with astringent drugs kidney tonifying; Radix Codonopsis has the effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting; The Radix Astragali has that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating are admittedly de-, wind dispelling is transported malicious effect; Herba Epimedii has the effect of kidney-replenishing, bone and muscle strengthening, wind-damp dispelling; Radix Dipsaci has the effect of invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating; Pericarpium Citri Reticulatae has the effect of diuretic, drying dampness to eliminate phlegm in regulating qi-flowing for strengthening spleen, tune; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component is through dialectical compatibility, helps using mutual assistant, plays altogether the effect that nourishing the liver and kidney, spermatogenesis are mended marrow, vigorate qi and replenish the blood, blood circulation promoting and blood stasis dispelling, and the treatment of few essence, azoospermia is reached to treating both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, does not occur toxic and side effects, and effective percentage reaches 95%, cure rate 65%.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for few essence, azoospermia, its raw material of Chinese medicine and weight proportion are: Fructus Lycii 20g, Semen Cuscutae 15g, Fructus Rubi 15g, Fructus Schisandrae Chinensis 10g, Semen Plantaginis 12g, Fructus Mori 10g, Radix Angelicae Sinensis 15g, Radix Rehmanniae Preparata 12g, Radix Polygoni Multiflori 20g, Radix Codonopsis 20g, Radix Astragali 20g, Herba Epimedii 15g, Radix Dipsaci 15g, Pericarpium Citri Reticulatae 10g, Radix Glycyrrhizae 6g.
Embodiment 2
Treat a Chinese medicine composition for few essence, azoospermia, its raw material of Chinese medicine and weight proportion are: Fructus Lycii 15g, Semen Cuscutae 25g, Fructus Rubi 5g, Fructus Schisandrae Chinensis 20g, Semen Plantaginis 10g, Fructus Mori 15g, Radix Angelicae Sinensis 5g, Radix Rehmanniae Preparata 20g, Radix Polygoni Multiflori 15g, Radix Codonopsis 30g, Radix Astragali 10g, Herba Epimedii 25g, Radix Dipsaci 5g, Pericarpium Citri Reticulatae 20g, Radix Glycyrrhizae 12g.
Embodiment 3
Treat a Chinese medicine composition for few essence, azoospermia, its raw material of Chinese medicine and weight proportion are: Fructus Lycii 25g, Semen Cuscutae 10g, Fructus Rubi 20g, Fructus Schisandrae Chinensis 5g, Semen Plantaginis 15g, Fructus Mori 20g, Radix Angelicae Sinensis 5g, Radix Rehmanniae Preparata 15g, Radix Polygoni Multiflori 25g, Radix Codonopsis 10g, Radix Astragali 25g, Herba Epimedii 5g, Radix Dipsaci 20g, Pericarpium Citri Reticulatae 12g, Radix Glycyrrhizae 5g.
Embodiment 4
Treat a Chinese medicine composition for few essence, azoospermia, its raw material of Chinese medicine and weight proportion are: Fructus Lycii 10g, Semen Cuscutae 20g, Fructus Rubi 10g, Fructus Schisandrae Chinensis 15g, Semen Plantaginis 5g, Fructus Mori 12g, Radix Angelicae Sinensis 20g, Radix Rehmanniae Preparata 5g, Radix Polygoni Multiflori 10g, Radix Codonopsis 25g, Radix Astragali 10g, Herba Epimedii 20g, Radix Dipsaci 5g, Pericarpium Citri Reticulatae 15g, Radix Glycyrrhizae 10g.
Embodiment 5
Treat a Chinese medicine composition for few essence, azoospermia, its raw material of Chinese medicine and weight proportion are: Fructus Lycii 30g, Semen Cuscutae 5g, Fructus Rubi 25g, Fructus Schisandrae Chinensis 12g, Semen Plantaginis 20g, Fructus Mori 5g, Radix Angelicae Sinensis 25g, Radix Rehmanniae Preparata 10g, Radix Polygoni Multiflori 30g, Radix Codonopsis 15g, Radix Astragali 30g, Herba Epimedii 10g, Radix Dipsaci 25g, Pericarpium Citri Reticulatae 5g, Radix Glycyrrhizae 15g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and cover powder, soak 15～20 minutes, then add water and do not have approximately 6 centimetres of powder, decoct for the first time, adopt intense fire to decoct before at a simmer, after boiling with slow fire boiling 20～30 minutes; Decoct for the second time, add water and do not have approximately 4 centimetres of powder, after water boils, decoct 15～20 minutes.Decoct extracting juice twice, merge.
The present invention, with the given a kind of Chinese medicine composition for the treatment of few essence, azoospermia of embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation 80 cases, 25～40 years old age.
Two, diagnostic criteria:
Man and wife lives together more than 1 year, and sexual life is normal, does not take any contraceptives and sterile, gets rid of on inspection wife's side factor person.Semen efamination refers to extremely: 1. sperm concentration <60 * 109/L; 2. motility of sperm a level adds b level <30% or a level <10%; 3. sperm motility rate <60%.Above three possess one and can make a definite diagnosis.
Three, usage and dosage: during clinical practice, potion on the one, the about 400ml of twice extracting juice of decocting, minute morning, late twice empty stomach decoction being taken warmly.It within 15 days, is a course for the treatment of.During treatment, stop other any medicines, advise patient ban on opium-smoking and the opium trade wine, savoury far away, tired, avoid work in hot environment and hot water bathing, avoid industrial pollution, lonizing radiation and electromagnetic wave, wear the loose underwear of cotton, note nutritive equilibrium, and advise spouse of patient to be extraordinarily concerned about, to encourage, to alleviate patient's pressure, to heighten one's confidence.
Four, criterion of therapeutical effect:
According to the < < of World Health Organization (WHO) (WH0) infertile couples standard, check the > with diagnosis handbook >, and evaluate with reference to relevant criterion of therapeutical effect in < < new Chinese medicine guideline of clinical investigations > >.
(1) cure: sperm concentration >=20 * 109/L after oligospermia treatment, azoospermia motility of sperm a level adds b level >=50% or a level >=25%, survival rate 1h >=60%; Or after treatment, the wife's side is conceived.
(2) effective: after oligospermia treatment, sperm concentration promotes >=50%, azoospermia motility of sperm a level adds the lifting >=25% of b level or a level promotes >=12.5%, and survival rate 1h promotes >=50%, but does not reach normal index.
(3) effective: oligospermia is treated rear sperm concentration and promoted >=15%, after azoospermia treatment, motility of sperm a adds b level or a level lifting >=5%, survival rate 1h lifting >=15%;
(4) invalid: after treatment, sperm concentration, survival rate <15% and motility of sperm promote <5% or unchanged.
Five, therapeutic effect: in this clinical observation case, take medicine 2-5 the course for the treatment of, recovery from illness 52 examples, follow up a case by regular visits to and have no recurrence; Effective 15 examples, effective 9 examples, invalid 4 examples.During treatment, there is not toxic and side effects.
Six, model case:
Case 1:
Cui, man, 32 years old.3 years after marriage always last pregnant.The wife's side checks without abnormal.Be diagnosed as on inspection: oligospermia.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, check seminal fluid counting: 8 00 ten thousand/ml, continues to take 2 courses for the treatment of, seminal fluid counting 4,000 ten thousand/ml, and next year, its wife was pregnant.
Case 2:
Normal certain, man, 28 years old.Because of 2 years after marriage infertile the going to a doctor of wife.Patient's readme: live together after marriage, sexual life is normal, 2-3 time weekly, because seeking medical advice infertile once many places, but equal unsatisfactory curative effect.Husband was once diagnosed as do semen efamination: azoospermia.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, check seminal fluid counting 3,500 ten thousand/ml, advise it in the wife's sexual intercourse onset of ovulation, within inferior month, confirm conceived.
Case 3:
Jiang, man, 35 years old.Marry for many years, its wife is never conceived, through examination in hospital result, is oligospermia.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, look into seminal fluid counting 3,000 ten thousand/ml; Continue to take 3 courses for the treatment of, its wife is conceived.
Claims (2)
1. a Chinese medicine composition for the treatment of few essence, azoospermia, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Fructus Lycii 10-30 part, Semen Cuscutae 5-25 part, Fructus Rubi 5-25 part, Fructus Schisandrae Chinensis 5-20 part, Semen Plantaginis 5-20 part, Fructus Mori 5-20 part, Radix Angelicae Sinensis 5-25 part, Radix Rehmanniae Preparata 5-20 part, Radix Polygoni Multiflori 10-30 part, Radix Codonopsis 10-30 part, Radix Astragali 10-30 part, Herba Epimedii 5-25 part, Radix Dipsaci 5-25 part, Pericarpium Citri Reticulatae 5-20 part, Radix Glycyrrhizae 5-15 part.
2. a kind of Chinese medicine composition for the treatment of few essence, azoospermia according to claim 1, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 20 parts of Fructus Lyciis, 15 parts of Semen Cuscutae, 15 parts of Fructus Rubies, 10 parts of Fructus Schisandrae Chinensis, 12 parts of Semen Plantaginiss, 10 parts of Fructus Mori, 15 parts of Radix Angelicae Sinensis, 12 parts, Radix Rehmanniae Preparata, 20 parts of Radix Polygoni Multiflori, 20 parts of Radix Codonopsis, 20 parts of the Radixs Astragali, 15 parts of Herba Epimedii, 15 parts of Radix Dipsaci, 10 parts of Pericarpium Citri Reticulataes, 6 parts, Radix Glycyrrhizae.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105770427A (en) * | 2016-04-24 | 2016-07-20 | 邹洪胜 | Traditional Chinese medicine composition for treating oligospermia and asthenozoospermia |
| CN106109864A (en) * | 2016-04-20 | 2016-11-16 | 周充敬 | A kind of Chinese medicine preparation treating the few essence of male's azoospermia and preparation method |
| CN108771716A (en) * | 2018-09-10 | 2018-11-09 | 王璀琳 | A kind of Chinese medicine composition and preparation method thereof for male sterility |
| CN110090271A (en) * | 2019-05-27 | 2019-08-06 | 卓进盛 | A kind of Chinese medicine composition that treating male sterility, preparation and its application |
| CN115944687A (en) * | 2023-02-03 | 2023-04-11 | 宜春学院 | Traditional Chinese medicine formula for improving male idiopathic oligospermia, decoction and tablet |
Citations (1)
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| CN102908517A (en) * | 2012-10-11 | 2013-02-06 | 赵子山 | Chinese medicine composition for curing oligospermia and asthenozoospermia and preparation method of Chinese medicine composition |
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2014
- 2014-01-09 CN CN201410008849.3A patent/CN103705641A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102908517A (en) * | 2012-10-11 | 2013-02-06 | 赵子山 | Chinese medicine composition for curing oligospermia and asthenozoospermia and preparation method of Chinese medicine composition |
Non-Patent Citations (1)
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| 金维新等: "生精汤与液化汤治疗男性不育症-附248例临床分析", 《中医杂志》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106109864A (en) * | 2016-04-20 | 2016-11-16 | 周充敬 | A kind of Chinese medicine preparation treating the few essence of male's azoospermia and preparation method |
| CN105770427A (en) * | 2016-04-24 | 2016-07-20 | 邹洪胜 | Traditional Chinese medicine composition for treating oligospermia and asthenozoospermia |
| CN108771716A (en) * | 2018-09-10 | 2018-11-09 | 王璀琳 | A kind of Chinese medicine composition and preparation method thereof for male sterility |
| CN110090271A (en) * | 2019-05-27 | 2019-08-06 | 卓进盛 | A kind of Chinese medicine composition that treating male sterility, preparation and its application |
| CN115944687A (en) * | 2023-02-03 | 2023-04-11 | 宜春学院 | Traditional Chinese medicine formula for improving male idiopathic oligospermia, decoction and tablet |
| CN115944687B (en) * | 2023-02-03 | 2024-01-26 | 宜春学院 | Traditional Chinese medicine formula, decoction and tablet for improving male idiopathic oligospermia |
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