CN104306502B - A kind of granule treating avian viral disease - Google Patents

A kind of granule treating avian viral disease Download PDF

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Publication number
CN104306502B
CN104306502B CN201410614639.9A CN201410614639A CN104306502B CN 104306502 B CN104306502 B CN 104306502B CN 201410614639 A CN201410614639 A CN 201410614639A CN 104306502 B CN104306502 B CN 104306502B
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parts
granule
viral disease
avian viral
disease
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Expired - Fee Related
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CN201410614639.9A
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CN104306502A (en
Inventor
程梅
吴玉龙
李波清
倪天辉
赵冬梅
张玉梅
杜镇镇
周秀芝
耿丽
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Binzhou Medical College
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Binzhou Medical College
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/10Bryophyta (mosses)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/41Crassulaceae (Stonecrop family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to a kind of granule treating avian viral disease, be made up of Chinese medicines such as bee saage, hypericum erectum, big hypericum japonicums, and be prepared as granule, the avian viral diseases such as newcastle disease can be prevented and treated.

Description

A kind of granule treating avian viral disease
Technical field
The present invention relates to a kind of veterinary drug, particularly to a kind of granule treating avian viral disease and preparation method thereof and Application.
Background technology
Avian influenza virus (AIV) belongs to influenza A virus.Influenza virus belongs to the orthomyxovirus section of RNA virus, point first, Second, the third 3 types.Wherein influenza A virus is mainly in bird, and some A types also can infected pigs, horse, sea dog and whale Etc. various mammals and the mankind;B-mode and influenza virus C sees the infection of sea dog and pig the most respectively.The most not yet Find to be exclusively used in poultry virus disease particularly to newcastle disease treatment or the special veterinary drug of prevention.Newcastle disease be by Newcastle disease virus (Newcastle disease virus}NDV) a kind of high degree in contact caused, acute, septic Infectious disease, this disease incidence of disease and fatal rate are up to more than 90%, are China's aviculture harm maximums, and economic loss is the most serious One of poultry diease.The most not yet find at present to be exclusively used in poultry virus disease particularly special to newcastle disease treatment or prevention Use veterinary drug.
Summary of the invention
In view of the deficiencies in the prior art, it is an object of the invention to provide treat a kind of avian viral disease powder and Preparation method, this Chinese medicine composition is evident in efficacy.
The object of the present invention is achieved like this:
A kind of granule treating avian viral disease, it prepares by the raw material of following parts by weight: bee saage 15 parts, Hypericum erectum 10 parts, big hypericum japonicum 8 parts, big Herba Kalimeridis 16 parts, wild citron 12 parts, take root 14 parts, the mountain valley with clumps of trees and bamboo Aunt's grass 9 parts, capitate knotweed herb 12 parts, common aeschynomene leaf 10 parts, rose rhodobryum herb 12 parts, Lepidium apetalum 8 parts.
A kind of granule treating avian viral disease, preparation method comprises the steps: to take above-mentioned Chinese medicine, beats powder system Standby one-tenth granule, crosses 100 mesh sieves.
The application in preparation treatment avian viral disease medicine of the described treatment avian viral disease granule.
Bee saage is Labiatae bee saage platymiscium bee saage Hyptis suaveolens (L.) Poir., with all herbal medicine.Xia Qiu Gather, dry in the shade or using fresh herb.Dispelling wind dampness removing, promoting the circulation of qi dissipates the stasis of blood.For cold headache, gastroenteritis, dysentery, abdominal distension;Outward With controlling treating swelling and pain by traumatic injury, traumatic bleeding, carbuncle sore tumefacting virus, worm snake bite, eczema, dermatitis.
Hypericum erectum is the herb of perennial dicotyledon medicine Garcinia maingayii hypericum erectum.Up to 30~60 centimetres, smooth Without hair.Stem is cylindrical.It is born in hill.All there is distribution the greater part, the whole nation.Regulating menstruation, hemostasis, removing toxicity for detumescence.For the moon Through uncomfortable, hemorrhage of digestive tract, spit blood, bleeding from five sense organs or subcutaneous tissue;Traumatism and bleeding, furuncle swelling toxin, venomous snake bite are controlled in external application.
Big hypericum japonicum is red Lysimachia sikokiana Lysimachia fortunei Maxim. of Primulaceae Lysimachia plant, enters with herb Medicine.Summer, autumn gather, and clean, dry, and segment or binding are standby.Clearing heat and promoting diuresis, promoting blood circulation for regulating menstruation.For catching a cold, Cough spitting of blood, enteritis, dysentery, hepatitis, infantile malnutrition due to digestive disturbances or intestinalparasites, malaria, rheumatic arthritis, dysmenorrhoea, amenorrhoea, leukorrhea;Mammary gland Inflammation, conjunctivitis, snake bite, traumatic injury.
Big Herba Kalimeridis is composite family Rhynchospermum plant Rhynchospermum verticillatum Rhynchospermun;Verticillatum Reinw., with entirely Grass is used as medicine, and autumn gathers, and cleans, dries.Removing damp-heat.For acute hepatitis, chronic hepatitis, cirrhotic ascites, uterine bleeding, Leukorrhea.
Wild citron (formal name used at school: Capparis bodinieri) is the plant that Capparaceae Chinese lime belongs to.Complete stool is medicinal, heat-clearing Removing toxic substances;There are the effect of hemostasis, anti-inflammatory, convergence, dispelling, collateral-activating.Master has sore throat;Tonsillitis;Toothache;Carbuncle furuncle sore Poison;Venomous snake bite;Hemorrhoid;Arthralgia due to wind-dampness;Traumatic injury.Control various inside and outside the old and new's hemorrhoid (existing patent medicine is sold); Control again chronic rheumatoid pain and traumatic injury, be also used for contraception.
Take root and take root Kalanchoe pinnatum (L.) Pers. for the Crassulaceae platymiscium that takes root, With all herbal medicine.The whole year can adopt, many using fresh herbs.Removing toxicity for detumescence, promoting blood circulation and stopping pain, removing toxic substances and promoting tissue regeneration.Ulcerative carbuncle pyogenic infections is controlled in external application, Mastitis, erysipelas, the pyogenic infection of the pad of a finger, traumatism and bleeding, traumatic injury, fracture, burn and scald, tympanitis.
Mountain valley with clumps of trees and bamboo aunt grass (formal name used at school: Stellaria vestita) is the plant of Caryophyllaceae Stellaria.Herb hyoscine, can relaxing muscles and tendons Invigorate blood circulation.
Capitate knotweed herb is the herb of polygonaceae plant polygonum capitatum.Classification system Polygonum capitatum Buch detoxifies, and dissipates The stasis of blood, inducing diuresis for treating strangurtia.Control dysentery, pyelitis, cystitis, lithangiuria, rheumatalgia, traumatic injury, sore eczema. The present invention is with all herbal medicine.
The diseases such as common aeschynomene leaf is the leaf of legume ambatch, can treat carbuncle and swell, traumatic bleeding.
Rose rhodobryum herb, Latin entitled Rhodobryum roseum (Hedw.) Limpr. is pungent, bitter, flat.Mental-tranquilization, Clear liver and improve vision.For palpitation and severe palpitation, neurasthenia, red eye, swell pain is controlled in external application.Perennial bryophyte;Much the most scattered Raw;Root state stem horizontal walk, have most hairy rhizoid.Stem racemosus, uprightly, aubergine.Inferior leads is tiny, film quality, squama Sheet adhesion is in stem;Stem top is green, relatively grows up, and multilevel cluster becomes rosette-stape, the blade shape of falling ovum lanceolar or length to fall Avette, serration, bottom Quan Yuan are arranged at top, and involute, middle rib is up to blade tip.The several sporinite of bunch life in stem top clump; Seta is elongated, upper end bow, and sporangium is sagging, reddish yellow, long oval cylindricality, and opercule is convex, has short beak.The present invention with All herbal medicine.
Lepidium apetalum (formal name used at school: Lepidium apetalum) is the plant of Cruciferae separate row Vegetable spp.Cough-relieving, Eliminate the phlegm, relieving asthma, heat-clearing, removing toxic substances.The present invention is with all herbal medicine.
Present invention is generally directed to gal virus sick, such as sides such as deadly infectious disease ewcastle disease, Bursal Diseases Face determined curative effect, the especially virus to ewcastle disease have direct inhibitory or killing effect.
Application example:
Use medicine: prepare according to the method for the embodiment of the present invention 1.
Clinical symptoms: find indivedual chicken snore, sound of shouting strangely in 40 laying hen groups, get rid of nose, cough, individually The chicken depressed necking down of spirit, respiratory symptom increases the weight of then, and chicken appetite of mining massively begins to decline, and serious can subtract 1/3, The most individual other intimate exhausted water of going on a hunger strike, ight soil is the dilutest, yellowish-white creamy in blue-green, and bronzing ight soil increases later Many, now eggshell color shoals, and laying rate is slightly decreased.More typical chicken performance larynx hyperemia flush, gas Pipe hyperemia has foam-like secretion, and heart hat fat and cardiac muscle are hemorrhage.
Diagnosis: newcastle disease disease.
Treatment: treating with product of the present invention, be used in conjunction 5 days, symptom is recovered substantially;After chicken group's transference cure mostly Performance eggshell shoals, and subtracts the symptom of egg, coordinates nutritional drugs simultaneously, recovers the function of laying eggs of chicken.
Detailed description of the invention
The foregoing of the present invention is described in further detail by form below by way of preparation embodiment again, but should not This is interpreted as, and the scope of the above-mentioned theme of the present invention is only limitted to Examples below, all is realized based on foregoing of the present invention Technology belong to the scope of the present invention.
Embodiment 1:
Take bee saage 15g, hypericum erectum 10g, big hypericum japonicum 8g, big Herba Kalimeridis 16g, wild citron 12g, land Take root 14g, mountain valley with clumps of trees and bamboo aunt grass 9g, capitate knotweed herb 12g, common aeschynomene leaf 10g, rose rhodobryum herb 12g, Lepidium apetalum 8g, beat powder It is prepared as granule, crosses 100 mesh sieves.

Claims (3)

1. the granule treating avian viral disease, it is characterised in that it is prepared by the raw material of following parts by weight: Bee saage 15 parts, hypericum erectum 10 parts, big hypericum japonicum 8 parts, big Herba Kalimeridis 16 parts, wild citron 12 parts, take root 14 parts, the mountain valley with clumps of trees and bamboo aunt grass 9 parts, capitate knotweed herb 12 parts, common aeschynomene leaf 10 parts, rose rhodobryum herb 12 parts, Lepidium apetalum 8 parts.
A kind of granule treating avian viral disease the most according to claim 1, it is characterised in that preparation method includes as follows Step: take above-mentioned Chinese medicine, beats powder and is prepared as granule.
Treatment avian viral disease granule the most according to claim 1 is in preparation treatment avian viral disease medicine Application.
CN201410614639.9A 2014-11-04 2014-11-04 A kind of granule treating avian viral disease Expired - Fee Related CN104306502B (en)

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CN104306502B true CN104306502B (en) 2016-08-24

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104906246A (en) * 2015-06-05 2015-09-16 徐艳 Veterinary medicine for treating avian virosises

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C41 Transfer of patent application or patent right or utility model
CB03 Change of inventor or designer information

Inventor after: Cheng Mei

Inventor after: Wu Yulong

Inventor after: Li Boqing

Inventor after: Ni Tianhui

Inventor after: Zhao Dongmei

Inventor after: Zhang Yumei

Inventor after: Du Zhenzhen

Inventor after: Zhou Xiuzhi

Inventor after: Geng Li

Inventor before: Li Zhengmei

COR Change of bibliographic data
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Effective date of registration: 20160719

Address after: Laishan District of Shandong city of Yantai province Guanhai road 264003 No. 346

Applicant after: Binzhou Medical University

Address before: 211200, Shenlong pharmaceutical industry, 28 Town, Nanjing Town, Lishui District, Jiangsu, China

Applicant before: Li Zhengmei

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