CN104306502A - Granule for treating avian viral diseases - Google Patents

Granule for treating avian viral diseases Download PDF

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Publication number
CN104306502A
CN104306502A CN201410614639.9A CN201410614639A CN104306502A CN 104306502 A CN104306502 A CN 104306502A CN 201410614639 A CN201410614639 A CN 201410614639A CN 104306502 A CN104306502 A CN 104306502A
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parts
granule
herba
avian viral
viral disease
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CN201410614639.9A
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CN104306502B (en
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李正梅
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Binzhou Medical College
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/10Bryophyta (mosses)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/41Crassulaceae (Stonecrop family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a granule for treating avian viral diseases. The granule is prepared from traditional Chinese medicines such as bee sage, hypericum erectum, lysimachia fortunei maxim and the like; the traditional Chinese medicines are prepared into the granule capable of preventing and treating avian viral diseases such as Newcastle disease and the like.

Description

A kind of granule for the treatment of avian viral disease
Technical field
The present invention relates to a kind of veterinary drug, particularly a kind of granule for the treatment of avian viral disease and its preparation method and application.
Background technology
Bird flu virus (AIV) belongs to influenza A virus.Influenza virus belongs to the orthomyxovirus section of RNA viruses, point first, second, the third 3 types.Wherein influenza A virus is mainly in birds, some A types also can infected pigs, horse, various mammal and the mankind such as sea dog and whale; B-mode and influenza virus C then sees the infection of sea dog and pig respectively.Not yet find at present to be exclusively used in poultry virus disease particularly to the special veterinary drug that newcastle disease is treated or prevented.Newcastle disease is a kind of high degree in contact, acute, the septic infectious disease that are caused by newcastle disease virus (Newcastle disease virus}NDV), this sick sickness rate and fatality rate are up to more than 90%, that China's aviculture harm is maximum, one of fowl diseases that economic loss is the most serious.Not yet find at present to be exclusively used in poultry virus disease particularly to the special veterinary drug that newcastle disease is treated or prevented.
Summary of the invention
In view of the deficiencies in the prior art, the object of the present invention is to provide powder for the treatment of a kind of avian viral disease and preparation method thereof, this Chinese medicine composition is evident in efficacy.
The object of the present invention is achieved like this:
Treat a granule for avian viral disease, it is prepared by the raw material of following parts by weight: Caulis et Folium Hyptidis suaveolentis 15 parts, Herba Hyperici Erecti 10 parts, large Herba Hyperici Japonici 8 parts, large Herba Kalimeridis 16 parts, wild Fructus Citri 12 parts, Herba Bryophylli Pinnati 14 parts, mountain valley with clumps of trees and bamboo aunt grass 9 parts, Herba Polygoni Capitati 12 parts, Folium Aeschynomenes indicae 10 parts, Rhodobryum roseum Limpr. 12 parts, Lepidium sativum L. 8 parts.
Treat a granule for avian viral disease, preparation method comprises the steps: to get above-mentioned Chinese medicine, beats powder and is prepared into granule, crosses 100 mesh sieves.
The application of described treatment avian viral disease granule in preparation treatment avian viral disease medicine.
Caulis et Folium Hyptidis suaveolentis is Labiatae Caulis et Folium Hyptidis suaveolentis platymiscium Caulis et Folium Hyptidis suaveolentis Hyptis suaveolens (L.) Poir., with all herbal medicine.Xia Qiu gathers, and dries in the shade or using fresh herb.Dispelling wind dampness removing, circulation of qi promoting dissipating blood stasis.For headache due to common cold, gastroenteritis, dysentery, abdominal distention; Treating swelling and pain by traumatic injury is controlled in external, wound hemorrhage, carbuncle sore tumefacting virus, worm venom, eczema, dermatitis.
Herba Hyperici Erecti is the herb of perennial dicotyledon medicine Garcinia maingayii Herba Hyperici Erecti.Up to 30 ~ 60 centimetres, Glabrous.Stem is cylindrical.Be born in hill.All there is distribution the greater part, the whole nation.Regulating menstruation, hemostasis, removing toxic substances and promoting subsidence of swelling.For menoxenia, digestive tract hemorrhage, spits blood, epistaxis; Traumatic hemorrhage is controlled in external, furuncle swelling toxin, venom.
Large Herba Hyperici Japonici is Primulaceae Lysimachia plant Arisaema balansae Engl. Herba lysimachiae capillipedis Lysimachia fortunei Maxim., with all herbal medicine.Summer, autumn gather, clean, dry, cutting or binding for subsequent use.Clearing away heat-damp and promoting diuresis, promoting blood flow to regulate menstruation.For flu, cough spitting of blood, enteritis, dysentery, hepatitis, infantile malnutrition, malaria, rheumatic arthritis, dysmenorrhea, amenorrhea, leucorrhea; Mastitis, conjunctivitis, venom, traumatic injury.
Large Herba Kalimeridis is Compositae Rhynchospermum plant Rhynchospermum verticillatum Rhynchospermun; Verticillatum Reinw., with all herbal medicine, autumn gathers, and cleans, dries.Removing damp-heat.For acute hepatitis, chronic hepatitis, cirrhotic ascites, metrorrhagia, leucorrhea.
Wild Fructus Citri (formal name used at school: Capparis bodinieri) is the plant that Capparaceae Chinese lime belongs to.Herb is medicinal, heat-clearing and toxic substances removing; There is the effect of hemostasis, antiinflammatory, convergence, dispelling, collateral-activating.Master has sore throat; Tonsillitis; Toothache; Carbuncle furuncle poison; Venom; Hemorrhoid; Rheumatic arthralgia; Traumatic injury.Control various inside and outside the old and new's hemorrhoid (existing patent medicine is sold); Control again chronic rheumatoid pain and traumatic injury, also for contraception.
Herba Bryophylli Pinnati is Crassulaceae Herba Bryophylli Pinnati platymiscium Herba Bryophylli Pinnati Kalanchoe pinnatum (L.) Pers., with all herbal medicine.The whole year can adopt, many using fresh herbs.Removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, removing toxic substances and promoting tissue regeneration.Carbuncle pyogenic infections from tumour or sore is controlled in external, mastitis, erysipelas, panaris, traumatic hemorrhage, traumatic injury, fracture, burn and scald, otitis media.
Mountain valley with clumps of trees and bamboo aunt grass (formal name used at school: Stellaria vestita) is the plant of Caryophyllaceae Stellaria.Herb hyoscine, can relaxing muscles and tendons to promote blood circulation.
Herba Polygoni Capitati is the herb of polygonaceae plant Herba Polygoni Capitati.Classification system Polygonum capitatum Buch detoxifies, dissipating blood stasis, inducing diuresis for treating stranguria syndrome.Control dysentery, pyelitis, cystitis, lithangiuria, rheumatalgia, traumatic injury, skin infection eczema.The present invention is with all herbal medicine.
Folium Aeschynomenes indicae is the leaf of leguminous plant Herba Aeschynonenes Indicae, can treat carbuncle, the diseases such as wound hemorrhage.
Rhodobryum roseum Limpr., Latin is called Rhodobryum roseum (Hedw.) Limpr., pungent, bitter, flat.Tranquilizing by nourishing the heart, liver heat removing and eyesight improving.For severe palpitation, neurasthenia, conjunctival congestion and swelling pain is controlled in external.Perennial bryophyte; How scattered in flakes; Root state stem horizontal walk, have most hair shape rhizoid.Stem racemosus, uprightly, aubergine.Inferior leads is tiny, film quality, and flakey adhesion is in stem; Stem top is green, and comparatively grow up, multilevel cluster becomes rosette-stape, the blade shape of falling ovum lanceolar or long inverted ovoid, and serration is arranged at top, bottom Quan Yuan, and involute, middle rib reaches blade tip.Cluster in stem top clump several sporinite; Seta is elongated, upper end bow, and sporangium is sagging, reddish yellow, long oval cylindricality, and opercule is convex, has short beak.The present invention is with all herbal medicine.
Lepidium sativum L. (formal name used at school: Lepidium apetalum) is the plant of Cruciferae separate row Vegetable spp.Cough-relieving, eliminates the phlegm, and relievings asthma, heat clearing away, removing toxic substances.The present invention is with all herbal medicine.
The present invention is sick mainly for gal virus, as aspect determined curative effects such as deadly infectious disease newcastle, infectious bursal diseases, has direct inhibitory or killing effect especially to the virus of newcastle.
Application example:
Use medicine: prepare according to the method for the embodiment of the present invention 1.
Clinical symptoms: find indivedual chicken snore, sound of shouting strangely, ataxia, cough in 40 laying hen groups, the depressed necking down of indivedual chicken spirit, then respiratory symptom increases the weight of, chicken mine massively appetite start decline, serious can subtract 1/3, extremely individual other is close to exhausted water of going on a hunger strike, feces is general partially rare, and in aeruginous HUANGBAI(sic) milk shape, bronzing feces increased afterwards, now eggshell color shoals, and laying rate slightly declines.The congested flushing of more typical chicken performance larynx, trachea hyperemia has cystose secretions, and heart hat is fatty and cardiac muscle is hemorrhage.
Diagnosis: newcastle disease disease.
Treatment: with product treatment of the present invention, be used in conjunction 5 days, symptom is recovered substantially; Mostly show eggshell after chicken group transference cure to shoal, subtract the symptom of egg, coordinate nutritional drugs simultaneously, recover the function of laying eggs of chicken.
Detailed description of the invention
Form below by way of preparation embodiment is described in further detail foregoing of the present invention again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
Embodiment 1:
Get Caulis et Folium Hyptidis suaveolentis 15g, Herba Hyperici Erecti 10g, large Herba Hyperici Japonici 8g, large Herba Kalimeridis 16g, wild Fructus Citri 12g, Herba Bryophylli Pinnati 14g, the mountain valley with clumps of trees and bamboo aunt grass 9g, Herba Polygoni Capitati 12g, Folium Aeschynomenes indicae 10g, Rhodobryum roseum Limpr. 12g, Lepidium sativum L. 8g, beat powder and be prepared into granule, cross 100 mesh sieves.

Claims (3)

1. treat the granule of avian viral disease for one kind, it is characterized in that, it is prepared by the raw material of following parts by weight: Caulis et Folium Hyptidis suaveolentis 15 parts, Herba Hyperici Erecti 10 parts, large Herba Hyperici Japonici 8 parts, large Herba Kalimeridis 16 parts, wild Fructus Citri 12 parts, Herba Bryophylli Pinnati 14 parts, mountain valley with clumps of trees and bamboo aunt grass 9 parts, Herba Polygoni Capitati 12 parts, Folium Aeschynomenes indicae 10 parts, Rhodobryum roseum Limpr. 12 parts, Lepidium sativum L. 8 parts.
2. a kind of granule for the treatment of avian viral disease according to claim 1, is characterized in that, preparation method comprises the steps: to get above-mentioned Chinese medicine, beats powder and is prepared into granule, crosses 100 mesh sieves.
3. the application for the treatment of avian viral disease granule according to claim 1 in treatment avian viral disease medicine.
CN201410614639.9A 2014-11-04 2014-11-04 A kind of granule treating avian viral disease Expired - Fee Related CN104306502B (en)

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CN104306502B CN104306502B (en) 2016-08-24

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104906246A (en) * 2015-06-05 2015-09-16 徐艳 Veterinary medicine for treating avian virosises

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
吴贻谷: "《中国医学百科全书》", 31 October 1991, article "星宿菜", pages: 85 *
庞声航: "《实用瑶药学》", 30 November 2008, article "头花蓼", pages: 185-186 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104906246A (en) * 2015-06-05 2015-09-16 徐艳 Veterinary medicine for treating avian virosises

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CB03 Change of inventor or designer information

Inventor after: Cheng Mei

Inventor after: Wu Yulong

Inventor after: Li Boqing

Inventor after: Ni Tianhui

Inventor after: Zhao Dongmei

Inventor after: Zhang Yumei

Inventor after: Du Zhenzhen

Inventor after: Zhou Xiuzhi

Inventor after: Geng Li

Inventor before: Li Zhengmei

COR Change of bibliographic data
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Effective date of registration: 20160719

Address after: Laishan District of Shandong city of Yantai province Guanhai road 264003 No. 346

Applicant after: Binzhou Medical University

Address before: 211200, Shenlong pharmaceutical industry, 28 Town, Nanjing Town, Lishui District, Jiangsu, China

Applicant before: Li Zhengmei

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