CN103919983A - Antiviral and antibacterial mixture for preventing and treating upper respiratory tract infection of livestock and poultry - Google Patents

Antiviral and antibacterial mixture for preventing and treating upper respiratory tract infection of livestock and poultry Download PDF

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CN103919983A
CN103919983A CN201410171324.1A CN201410171324A CN103919983A CN 103919983 A CN103919983 A CN 103919983A CN 201410171324 A CN201410171324 A CN 201410171324A CN 103919983 A CN103919983 A CN 103919983A
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herba
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岳治光
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HENAN ANJIN BIOLOGY MEDICAL TECHNOLOGY Co Ltd
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HENAN ANJIN BIOLOGY MEDICAL TECHNOLOGY Co Ltd
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Abstract

The invention relates to an antiviral and antibacterial mixture for preventing and treating upper respiratory tract infection of livestock and poultry. The mixture comprises the following components: 6-7 parts of dandelion, 6-7 parts of bunge corydalis herb, 2-4 parts of subprostrate sophora, 2-3 parts of chrysanthemum, 3-5 parts of andrographis paniculata, 2-4 parts of radices trichosanthis, 2-4 parts of fritillaria, 3-4 parts of tussilago farfara, 1-2 parts of golden cypress, 1.5-3 parts of jasmine and 0.5-1.5 parts of licorice. The antiviral and antibacterial mixture provided by the invention has the functions of clearing away heat and toxic materials, moistening lung and depressing qi, and ensuring anti-inflammation and detumescence, and is clinically applicable to fungus toxic heat sufferers and upper respiratory infection caused by influenza virus, such as livestock epidemic hot, pneumonitis, chronic respiratory and infectious rhinitis of livestock and poultry.

Description

Control upper respiratory tract infection of livestock antiviral, press down antibacterial mixture and method
Technical field
The present invention relates to poultry field of medicaments, particularly relate to a kind of antiviral of preventing and treating upper respiratory tract infection of livestock, press down antibacterial mixture and method.
Background technology
Fowl respiratory tract infection usually by viral, bacillary or fungoid disease because causing, common mycoplasma and escherichia coli mixed infection, escherichia coli and pasteurellosis bacillus or infectious bronchitis or infectious bursal disease virus mixed infection.The adverse effect of this mixed infection is often more serious compared with Simple infection, in poultry rearing process, management factors: for example: ventilation, humidity, dust or ammonia concentration are too high, all significant impacts that has to respiratory tract disease, the vaccination program of mistake or in the severe situation of environment, after inoculation respiratory tract disease live vaccine, may cause vaccine virus immunization untoward reaction, the existence of infecting in advance, also can cause the adverse reaction after inoculation Respiratory Disease Vaccine.Thus, in home poultry raising, the inducement of upper respiratory tract infection is a lot, it is very common unavoidable a kind of disease, and upper respiratory tract infection is in the situation that can not being effectively treated in time, be easy to enter lower respiratory tract, even cause pulmonary infection, so find the etiological cause of the disease in time, effecting a radical cure fast upper respiratory tract infection has become home poultry raising field technical problem urgently to be resolved hurrily.
Summary of the invention
Object of the present invention is for problems of the prior art, a kind of antiviral of preventing and treating upper respiratory tract infection of livestock is provided, presses down antibacterial mixture.This mixture medical science formula is reasonable, for upper respiratory tract infection specialized designs, can control at short notice upper respiratory disease, and use value is high.
For achieving the above object, the present invention adopts following technical scheme: a kind of antiviral of preventing and treating upper respiratory tract infection of livestock, press down antibacterial mixture, this mixture comprises following component: 6~7 parts of Herba Taraxacis, 6~7 parts of Herba Corydalis Bungeanaes, 2~4 parts of Radix Sophorae Tonkinensiss, 2~3 parts of Flos Chrysanthemis, 3~5 parts of Herba Andrographis, 2~4 parts of Radix Trichosanthis, 2~4 parts of Bulbus Fritillariae Uninbracteataes, 3~4 parts of Flos Farfaraees, 1~2 part of Cortex Phellodendri, 1.5~3 parts of Fructus Gardeniaes, 0.5~1.5 part, Radix Glycyrrhizae.
Preferably, the antiviral of described control upper respiratory tract infection of livestock, press down antibacterial mixture comprise following component: 6.7 parts of Herba Taraxacis, 6.7 parts of Herba Corydalis Bungeanaes, 3 parts of Radix Sophorae Tonkinensiss, 2.6 parts of Flos Chrysanthemis, 4 parts of Herba Andrographis, 3 parts of Radix Trichosanthis, 3 parts of Bulbus Fritillariae Uninbracteataes, 3 parts of Flos Farfaraees, 1.5 parts of Cortex Phellodendris, 2 parts of Fructus Gardeniaes, 1 part, Radix Glycyrrhizae.
A kind of antiviral of preventing and treating upper respiratory tract infection of livestock, press down the preparation method of antibacterial mixture: first take raw material by compositional range described in technique scheme: Herba Taraxaci, Herba Corydalis Bungeanae, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Trichosanthis, Bulbus Fritillariae Uninbracteatae, Cortex Phellodendri, Fructus Gardeniae, Radix Glycyrrhizae nine taste medicines decoct with water 1.5~2.5 hours, then add Flos Chrysanthemi, Flos Farfarae, decoct again twice, each 0.8~1.5 hour, filter, merging filtrate, filtrate is concentrated into 1.10~1.20 clear paste, hot testing temperature is 60 DEG C, when laying temperature to 35 DEG C~45 DEG C is following, adding ethanol fully stirs, make to reach 70~80% containing alcohol amount, after placing, filter, filtrate recycling ethanol, described in adding water to, choose 75~85% of raw material gross weight, adjust pH to 7.0, stir, cold preservation 70~75 hours, refrigerated storage temperature is 4~8 DEG C, filter, filtrate adjust pH to 7.0, add water to make with described and choose the medicinal liquid that raw material gross weight equates, shake up, leave standstill 10~15 hours, filter, fill, sterilizing, obtain mixture.
Preferably, the antiviral of described control upper respiratory tract infection of livestock, the preparation method that presses down antibacterial mixture is: first take raw material by compositional range described in technique scheme: Herba Taraxaci, Herba Corydalis Bungeanae, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Trichosanthis, Bulbus Fritillariae Uninbracteatae, Cortex Phellodendri, Fructus Gardeniae, Radix Glycyrrhizae nine taste medicines decoct with water 2 hours, then add Flos Chrysanthemi, Flos Farfarae, decoct again twice, each 1 hour, filter, merging filtrate, filtrate is concentrated into 1.10~1.20 clear paste, hot testing temperature is 60 DEG C, when laying temperature to 40 DEG C is following, adding ethanol fully stirs, make to reach 75% containing alcohol amount, after placing, filter, filtrate recycling ethanol, described in adding water to, choose 80% of raw material gross weight, , adjust pH to 7.0, stir, cold preservation 72 hours, refrigerated storage temperature is 4~8 DEG C, filter, filtrate adjust pH to 7.0, add water to make with described and choose the medicinal liquid that raw material gross weight equates, shake up, leave standstill 12 hours, filter, fill, sterilizing, obtain mixture.
Above-mentioned each raw material pharmacological property is analyzed as follows:
Herba Taraxaci: bitter, sweet, cold.Return liver, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For sore, acute mastitis, lung abscess, conjunctival congestion, pharyngalgia, jaundice due to damp-heat, pyretic stranguria.
Herba Corydalis Bungeanae: bitter, cold.GUIXIN, liver, large intestine channel.Function cures mainly: heat-clearing and toxic substances removing, loose joint detumescence.For epidemic disease flu, laryngopharynx swelling and pain, aphtha of the mouth and tongue, furuncle swells and ache, carbuncle carbuncle on the back, mumps erysipelas.
Radix Sophorae Tonkinensis: hardship, cold.Enter the heart, stomach, lung, large intestine channel.Function cures mainly: heat-clearing and toxic substances removing, relieving sore throat and diminishing swelling.For the laryngopharynx swelling and pain due to lung-fire pyretic toxicity, cough, eliminating stagnation is broken hard.
Flos Chrysanthemi: sweet, bitter, be slightly cold.Enter lung, liver, kidney channel.Function cures mainly: wind and heat dispersing, liver heat removing and eyesight improving, removing toxic substances.For anemopyretic cold, the conjunctival congestion and swelling pain due to flaming up of liver-fire.
Herba Andrographis: bitter, cold.Return lung, liver, spleen, large intestine, small intestine meridian.Function cures mainly: heat-clearing and toxic substances removing, dampness removing and diarrhea-relieving.The disease such as rush down for lung-heat cough with asthma, laryngopharynx swelling and pain, intestinal are yellow.
Radix Trichosanthis: sweet, bitter, sour, cold.Enter lung, stomach warp.Function cures mainly: promoting the production of body fluid to quench thirst, pathogenic fire reducing are moisturized, evacuation of pus is subsided a swelling.For thirsty, the cough caused by dryness hemoptysis of consumption of body fluid caused by febrile disease, dislike tire carbuncle sore etc.
Bulbus Fritillariae Uninbracteatae: bitter, sweet, be slightly cold.Enter lung, heart channel.Function cures mainly: removing heat-phlegm, moisturizing knot, and for the loose flaccidity of wart scrofula, void cough phthisical cough, newborn lung abscess skin ulcer, heat-phlegm spitting of blood etc.
Flos Farfarae: pungent, temperature.Enter lung meridian.Function cures mainly: lung moistening sending down the abnormal ascending QI, relieving cough and resolving phlegm.For warming the lung lung moistening, chronic cough lung abscess, cold fluid-retention dyspnea with fullness of the chest etc.
Cortex Phellodendri: bitter, cold.Enter kidney, bladder, large intestine channel.Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication, clearing away deficiency-heat.For pathopyretic ulcer, skin eczema, anxious slow intestinal Huang etc.
Fructus Gardeniae: hardship, cold.Enter the heart, liver, lung, stomach, tri-jiao channel.Function cures mainly: pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, cooling blood for hemostasis., conjunctival congestion and swelling pain thirsty for the heating due to skin ulcer general edema with yellowish skin poison, three warmers accumulated heat etc.
Radix Glycyrrhizae: sweet, flat.Enter 12 warps.Function cures mainly: for QI invigorating invigorating middle warmer, expelling phlegm for arresting cough, relieving spasm to stop pain, removing toxic substances pathogenic fire purging, the property of medicine etc. that is in harmonious proportion.
each combination of components Analysis on Mechanism:
Herba Taraxaci, Herba Corydalis Bungeanae, Radix Sophorae Tonkinensis, Flos Chrysanthemi can heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation is monarch drug; Radix Trichosanthis, Bulbus Fritillariae Uninbracteatae, Flos Farfarae can removing heat-phlegm, lung moistening sending down the abnormal ascending QI, relieving cough and resolving phlegm are ministerial drug; Herba Andrographis, phellodendron and gardenia can heat clearing and damp drying, pathogenic fire purging relieving restlessness removing toxic substances is assistant; Radix Glycyrrhizae expelling phlegm for arresting cough, relieving spasm to stop pain, all medicines of blending are for making medicine, and all medicines share, and play altogether effect of heat-clearing and toxic substances removing, relieving cough and resolving phlegm, lung moistening sending down the abnormal ascending QI, anti-inflammation detumescence, make the evil expelling heat from the exterior of the exterior and the interior and heal.
The present invention has following beneficial effect: the present invention has effect of heat-clearing and toxic substances removing, lung moistening sending down the abnormal ascending QI, anti-inflammation detumescence, is clinically applicable to upper respiratory tract infection heat as popular in domestic animal, lung plague, poultry chronic respiratory and the infective rhinitis etc. that bacterium pyretic toxicity Sheng person and viral influenza cause.Therapeutic effect is remarkable, and the cycle of curing the disease is short, and dosage is little, can the quick control state of an illness.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described.
Embodiment 1: a kind of antiviral of preventing and treating upper respiratory tract infection of livestock, press down antibacterial mixture, this mixture comprises following component: Herba Taraxaci 620g, Herba Corydalis Bungeanae 610 g, Radix Sophorae Tonkinensis 230 g, Flos Chrysanthemi 220 g, Herba Andrographis 480g, Radix Trichosanthis 390g, Bulbus Fritillariae Uninbracteatae 210 g, Flos Farfarae 320g, Cortex Phellodendri 190g, Fructus Gardeniae 290g, Radix Glycyrrhizae 60g.
When preparation, first take raw material by said components formula: Herba Taraxaci, Herba Corydalis Bungeanae, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Trichosanthis, Bulbus Fritillariae Uninbracteatae, Cortex Phellodendri, Fructus Gardeniae, Radix Glycyrrhizae nine taste medicines decoct with water 1.6 hours, then add Flos Chrysanthemi, Flos Farfarae, decoct again twice, each 0.9 hour, filter, merging filtrate, filtrate be concentrated into 1.10~1.20(60 DEG C heat survey) clear paste, when laying temperature to 40 DEG C is following, adding ethanol fully stirs, make to reach 72% containing alcohol amount, after placing, filter, filtrate recycling ethanol, add water to 2896ml, adjust pH to 7.0, stir, cold preservation (4~8 DEG C) 72 hours, filter, filtrate adjust pH to 7.0, add water and make the medicinal liquid of 3620ml, shake up, leave standstill 10 hours, filter, fill, sterilizing, obtain mixture.
Embodiment 2: a kind of antiviral of preventing and treating upper respiratory tract infection of livestock, press down antibacterial mixture, this mixture comprises following component: Herba Taraxaci 680g, Herba Corydalis Bungeanae 670 g, Radix Sophorae Tonkinensis 370 g, 300 parts of Flos Chrysanthemis, Herba Andrographis 400 g, Radix Trichosanthis 240 g, Bulbus Fritillariae Uninbracteatae 280 g, Flos Farfarae 380 g, Cortex Phellodendri 100 g, Fructus Gardeniae 200 g, Radix Glycyrrhizae 140 g.
When preparation, first take raw material by said components formula: Herba Taraxaci, Herba Corydalis Bungeanae, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Trichosanthis, Bulbus Fritillariae Uninbracteatae, Cortex Phellodendri, Fructus Gardeniae, Radix Glycyrrhizae nine taste medicines decoct with water 2.3 hours, then add Flos Chrysanthemi, Flos Farfarae, decoct again twice, each 1.1 hours, filter, merging filtrate, filtrate be concentrated into 1.10~1.20(60 DEG C heat survey) clear paste, when laying temperature to 37 DEG C is following, adding ethanol fully stirs, make to reach 78% containing alcohol amount, after placing, filter, filtrate recycling ethanol, add water to 2820ml, adjust pH to 7.0, stir, cold preservation (4~8 DEG C) 70 hours, filter, filtrate adjust pH to 7.0, add water and make the medicinal liquid of 3760ml, shake up, leave standstill 11 hours, filter, fill, sterilizing, obtain mixture.
Embodiment 3: a kind of antiviral of preventing and treating upper respiratory tract infection of livestock, press down antibacterial mixture, this mixture comprises following component: Herba Taraxaci 650 g, Herba Corydalis Bungeanae 650 g, Radix Sophorae Tonkinensis 380 g, Flos Chrysanthemi 240 g, Herba Andrographis 300 g, Radix Trichosanthis 250 g, Bulbus Fritillariae Uninbracteatae 370 g, Flos Farfarae 390 g, Cortex Phellodendri 100 g, Fructus Gardeniae 170 g, Radix Glycyrrhizae 120 g.
When preparation, first take raw material by said components formula: Herba Taraxaci, Herba Corydalis Bungeanae, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Trichosanthis, Bulbus Fritillariae Uninbracteatae, Cortex Phellodendri, Fructus Gardeniae, Radix Glycyrrhizae nine taste medicines decoct with water 2 hours, then add Flos Chrysanthemi, Flos Farfarae, decoct again twice, each 1 hour, filter, merging filtrate, filtrate be concentrated into 1.10~1.20(60 DEG C heat survey) clear paste, when laying temperature to 40 DEG C is following, adding ethanol fully stirs, make to reach 76% containing alcohol amount, after placing, filter, filtrate recycling ethanol, add water, adjust pH is to 3040ml, stir, cold preservation (4~8 DEG C) 74 hours, filter, filtrate adjust pH to 7.0, add water and make the medicinal liquid of 3620ml, shake up, leave standstill 14 hours, filter, fill, sterilizing, obtain mixture.
Embodiment 4: a kind of antiviral of preventing and treating upper respiratory tract infection of livestock, press down antibacterial mixture, this mixture comprises following component: Herba Taraxaci 670 g, Herba Corydalis Bungeanae 670 g, Radix Sophorae Tonkinensis 300 g, Flos Chrysanthemi 260 g, Herba Andrographis 400 g, Radix Trichosanthis 300 g, Bulbus Fritillariae Uninbracteatae 300 g, Flos Farfarae 300 g, Cortex Phellodendri 150 g, Fructus Gardeniae 200 g, Radix Glycyrrhizae 100 g.
When preparation: first take raw material by said components formula: Herba Taraxaci, Herba Corydalis Bungeanae, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Trichosanthis, Bulbus Fritillariae Uninbracteatae, Cortex Phellodendri, Fructus Gardeniae, Radix Glycyrrhizae nine taste medicines decoct with water 2 hours, then add Flos Chrysanthemi, Flos Farfarae, decoct again twice, each 1 hour, filter, merging filtrate, filtrate be concentrated into 1.10~1.20(60 DEG C heat survey) clear paste, when laying temperature to 40 DEG C is following, adding ethanol fully stirs, make to reach 76% containing alcohol amount, after placing, filter, filtrate recycling ethanol, add water to 2920ml, adjust pH to 7.0, stir, cold preservation (4~8 DEG C) 72 hours, filter, filtrate adjust pH to 7.0, add water and make the medicinal liquid of 3650ml, shake up, leave standstill 12 hours, filter, fill, sterilizing, obtain mixture.
test case:
1, Luyi County, Zhoukou City national wealth pig farm (drawing national wealth)
1. morbidity overview
1780 of breeding pigs are raised on this pig farm altogether, have sow, boar, big porker, feeder pig, nursery pig etc.In the pig sudden onset of No. 6 first purebred pig houses of in JIUYUE, 2013, hyperpyrexia, does not eat food, and No. 10, JIUYUE are arrived in state of an illness bamboo telegraph, big porker, and sow, middle pig, piglets be all morbidities almost.Not good with medication effects such as No. one, penicillin and streptomycin and Weirs.Be total to 1609 of sick pigs, dead 128, sickness rate 90%, mortality rate 8% No. 10 to JIUYUE.
2. clinical symptoms
Primary disease is very short incubation period, and several hours to a couple of days, sudden onset, and loss of appetite or absolutely useless, 41~42 DEG C of body temperature, lassitude, normal sleeping ground does not rise or lethargy, shiver with cold, rapid breathing, or have cough, stream clear water or dense silk fabric nasal mucus.Discharge of eye increases, eye conjunctiva flushing, and feces is dry, minority swine excrement band blood, yellow urine, generation miscarriage or premature labor that farrowing sow has, dermathemia, sick later stage skin cyanosis, especially obvious with have sharp ears, extremity and abdominal part place.About the course of disease 10 days, serious for 28 days.
3. pathological anatomy
Cut open inspection and see that systemic bleeding is more serious, endocardium, visceral pericardium, larynx is congested and hemorrhage, the subcutaneous edema on a large scale as seen in around throat and neck bottom.In trachea, have and be with in a large number foamed mucus, sometimes have the blood streak, pulmonary lesion takes on a red color as beef shape, the broadening of pulmonary lobule interstitial, the band bleeding blister foam of emerging between incision, the visible fibrinous pleurisy that stadium is long, even pericarditis, has the cellulose of yellow-white egg skin sample in lung surface, hydrothorax, pericardial fluid.The obvious congestion of liver,spleen,kidney and enlargement, kermesinus, part pig still has acute catarrhal gastroenteritis haemorrhagica.Lymph nodes of body as a whole (especially under jaw, hilus pulumonis, mediastinum and bronchial lymph nodes) is serious congested hemorrhage, outward appearance kermesinus.
3. tentative diagnosis and therapeutic regimen
Select Compound Amidopyrin Injection+injection injection benzylpenicillin potassium individual treatment, jumpbogroup drinking-water (YINQIAO extract)+amoxicillin of Weir (amoxicillin soluble powder).Be used in conjunction two days medicines, effect is not too obvious, the visible dyspnea of jumpbogroup pig, and ventral breathing seriously increases, and flows out glutinous purulence nose liquid.Used afterwards medicine DeGrain, 90% pig is greedy sleeping, happiness is slept, coughed, and symptom increases.
After morbidity, within the 4th day, seek help to I the guard station distributor of company, technician was invited to show up and saw and examine through scene the same day, and inquiring learns that poultry raiser also once had cold symptoms at swinery premorbid, was that swine influenza secondary pig lung plague infects through clinical appraisal.
Therapeutic scheme: technician adopts disease-resistant antibacterial mixture of the present invention (in the clinical trial phase) 500ml, is watered 200-300 jin, and whole day is drunk, and is used in conjunction 3-5 days.
Therapeutic effect: treat second day, the pig symptom of jumpbogroup pig 85% is eased, and temperature recovery is normal, cough symptom is gradually few, is after treatment effect, prevents that disease from showing effect repeatedly, adheres to medication two days.Treat the 4th day: whole swinery outward appearance transference cure, feed intake recover normal, cough transference cure,
2, Luyi County, Zhoukou City Li Si common chicken in morning plant
1. incidence
Raise 4000 of common chicken, there is the phenomenon such as snore, ataxia in 18 age in days chicken groups, but jumpbogroup spirit, searches for food substantially unchangedly, once used doxycycline hydrochloride treatment, the state of an illness is without continuing development, when 21 age in days, raiser probably misses the age of immune, then uses the immunity of 4 times of amount drinking-water of newcastle IV Seedling, after 2 days, be in a bad way, every day is dead more than 10, and when the highest dead 36, the guard station distributor of company that then comes is medical.
2. clinical symptoms
Feed intake declines, and spirit is tired, and feather is fluffy and disorderly, and part chicken eyelid swelled, is constantly got rid of head at chicken group cough, rhinorrhea, sneeze, and indivedual chickens have cackle.Chicken group draws yellow green, emerald green loose stool.
3. cut open inspection pathological changes
Cut open the visible air bag muddiness of inspection, thicken, have individually yellow cheese thing, have mucus in trachea, liver has fiber disposition in various degree to ooze out, and pericardial thickening follows fiber disposition to ooze out.The swelling of glandular stomach nipple, secretions is thick and heavy, and intestinal wall thickens, and the swelling of duodenum lymph follicle, has individually hemorrhage; Cecal tonsil swelling is hemorrhage; Hemorrhage of rectum; Kidney swelling.
4. laboratory diagnosis
A. E. coli detection: the aseptic collection chicken liver of dying of illness, plain agar sugar culture-medium cultivate after smear, Gram’s staining, microscopy, visible Gram-negative bacillus pumilis.
B. newcastle HI detects: prepare serum at hen house zones of different extraction chicken blood at random stand-by.On 96 hole V-type plates, the 1st to the 10th hole is to detecting sample well, and 11,12 carry out HI test for control wells.Result shows that the HI the lowest of tiring is 3log2, and soprano is 13log2, and dispersion is larger.
5. diagnostic result: according to clinical symptoms, cut open inspection pathological changes and laboratory and detect, tentative diagnosis is chicken chronic respiratory diseases, escherichia coli and newcastle mixed infection.
6. therapeutic scheme
A. strengthen feeding and management: cleaning feces, strengthen sterilization, add forced ventilation.
B. jumpbogroup uses the disease-resistant antibacterial mixture of company (in the clinical trial phase) 500ml to be watered 200-300 jin, and whole day is drunk, and is used in conjunction 2-3 days.Concentrate drinking-water the morning, uses the raw peace of intestinal afternoon and reach gram to stop concentrating drinking-water.
Therapeutic effect: use return visit in latter 3 days, jumpbogroup spirit takes a turn for the better, and respiratory tract sounds disappears substantially, and death stops.Suggestion raiser immune newcastle disease vaccine again.
3, clinical experiment conclusion:
Show according to modern pharmacological research, disease-resistant antibacterial mixture (Herba Taraxaci, Herba Corydalis Bungeanae, Radix Sophorae Tonkinensis, Flos Chrysanthemi, Herba Andrographis, Radix Trichosanthis, Bulbus Fritillariae Uninbracteatae, Flos Farfarae, Cortex Phellodendri, Fructus Gardeniae, Radix Glycyrrhizae) has the effects such as antibacterial, antiinflammatory preferably, antipyretic, relieving cough and resolving phlegm, lung moistening sending down the abnormal ascending QI, and antimicrobial spectrum is all wider, all can reduce the swollen tissue that inflammatory reaction causes.Can be widely used in clinically the upper respiratory tract infection of disease of viral infection and poultry.

Claims (4)

  1. An antiviral of preventing and treating upper respiratory tract infection of livestock, press down antibacterial mixture, it is characterized in that: this mixture comprises following component: 6~7 parts of Herba Taraxacis, 6~7 parts of Herba Corydalis Bungeanaes, 2~4 parts of Radix Sophorae Tonkinensiss, 2~3 parts of Flos Chrysanthemis, 3~5 parts of Herba Andrographis, 2~4 parts of Radix Trichosanthis, 2~4 parts of Bulbus Fritillariae Uninbracteataes, 3~4 parts of Flos Farfaraees, 1~2 part of Cortex Phellodendri, 1.5~3 parts of Fructus Gardeniaes, 0.5~1.5 part, Radix Glycyrrhizae.
  2. The antiviral of control upper respiratory tract infection of livestock according to claim 1, press down antibacterial mixture, it is characterized in that: this mixture comprises following component: 6.7 parts of Herba Taraxacis, 6.7 parts of Herba Corydalis Bungeanaes, 3 parts of Radix Sophorae Tonkinensiss, 2.6 parts of Flos Chrysanthemis, 4 parts of Herba Andrographis, 3 parts of Radix Trichosanthis, 3 parts of Bulbus Fritillariae Uninbracteataes, 3 parts of Flos Farfaraees, 1.5 parts of Cortex Phellodendris, 2 parts of Fructus Gardeniaes, 1 part, Radix Glycyrrhizae.
  3. 3. an antiviral as claimed in claim 1, press down the preparation method of antibacterial mixture, it is characterized in that: first take raw material by compositional range described in claim 1: Herba Taraxaci, Herba Corydalis Bungeanae, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Trichosanthis, Bulbus Fritillariae Uninbracteatae, Cortex Phellodendri, Fructus Gardeniae, Radix Glycyrrhizae nine taste medicines decoct with water 1.5~2.5 hours, then add Flos Chrysanthemi, Flos Farfarae, decoct again twice, each 0.8~1.5 hour, filter, merging filtrate, filtrate is concentrated into 1.10~1.20 clear paste, hot testing temperature is 60 DEG C, when laying temperature to 35 DEG C~45 DEG C is following, adding ethanol fully stirs, make to reach 70~80% containing alcohol amount, after placing, filter, filtrate recycling ethanol, described in adding water to, choose 75~85% of raw material gross weight, adjust pH to 7.0, stir, cold preservation 70~75 hours, refrigerated storage temperature is 4~8 DEG C, filter, filtrate adjust pH to 7.0, add water to make with described and choose the medicinal liquid that raw material gross weight equates, shake up, leave standstill 10~15 hours, filter, fill, sterilizing, obtain mixture.
  4. 4. antiviral according to claim 3, press down the preparation method of antibacterial mixture, it is characterized in that: first take raw material by compositional range described in claim 1: Herba Taraxaci, Herba Corydalis Bungeanae, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Trichosanthis, Bulbus Fritillariae Uninbracteatae, Cortex Phellodendri, Fructus Gardeniae, Radix Glycyrrhizae nine taste medicines decoct with water 2 hours, then add Flos Chrysanthemi, Flos Farfarae, decoct again twice, each 1 hour, filter, merging filtrate, filtrate is concentrated into 1.10~1.20 clear paste, hot testing temperature is 60 DEG C, when laying temperature to 40 DEG C is following, adding ethanol fully stirs, make to reach 75% containing alcohol amount, after placing, filter, filtrate recycling ethanol, described in adding water to, choose 80% of raw material gross weight, adjust pH to 7.0, stir, cold preservation 72 hours, refrigerated storage temperature is 4~8 DEG C, filter, filtrate adjust pH to 7.0, add water to make with described and choose the medicinal liquid that raw material gross weight equates, shake up, leave standstill 12 hours, filter, fill, sterilizing, obtain mixture.
CN201410171324.1A 2014-04-28 2014-04-28 Antiviral and antibacterial mixture for preventing and treating upper respiratory tract infection of livestock and poultry Pending CN103919983A (en)

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CN104885994A (en) * 2015-05-04 2015-09-09 霍邱县科瑞达禽业有限公司 Drinking water immunization method for chicken flock
CN106138257A (en) * 2016-08-23 2016-11-23 岳三邦 A kind of to burnt pathogenic fire purging mixture of poultry three and preparation method thereof

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CN104885994A (en) * 2015-05-04 2015-09-09 霍邱县科瑞达禽业有限公司 Drinking water immunization method for chicken flock
CN106138257A (en) * 2016-08-23 2016-11-23 岳三邦 A kind of to burnt pathogenic fire purging mixture of poultry three and preparation method thereof

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Application publication date: 20140716