CN107375866A - A kind of purposes of Chinese medicine composition in preparing for the somatotrophic medicine of piglet health care - Google Patents
A kind of purposes of Chinese medicine composition in preparing for the somatotrophic medicine of piglet health care Download PDFInfo
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Abstract
The invention discloses a kind of purposes of Chinese medicine composition in preparing for the somatotrophic medicine of piglet health care, the Chinese medicine composition is by the parts by weight of Yunnan astragalus 7~21,11~33 parts by weight of the open country of falling root Soviet Union, the parts by weight of evil mind kiss-me 6~18, the parts by weight of Rhizoma Zingiberis zerumbet 9~27, the parts by weight of nitraria schoberi 10~30 are made.The preparation method of said composition is by Yunnan astragalus, and the open country of falling root is revived, evil mind kiss-me, Rhizoma Zingiberis zerumbet, nitraria schoberi mixes, and 7~8 times of amount water of dosing material gross weight soak 8~12h, boil and maintain 1 2h, filtering, 5~6 times of dosing material gross weight measures water to filter residue again, boils and maintains 0.5 1h, filters, merge filtrate twice, be condensed into medicinal extract.The Chinese medicine composition adds in pig feed, can prevent and treat the infection or mixed infection of the viruses such as the pseudoabies after weaned piglet, PCV-II, haemophilus parasuis, bacterium, promotes growth, is also improved the effect of immunologic function, noresidue is safe and convenient to use.
Description
Technical field
The invention belongs to herbal medicine pharmaceutical field, and it is somatotrophic for piglet health care in preparation to be related to a kind of Chinese medicine composition
Purposes in medicine, the invention further relates to the Chinese medicine composition to prepare preventing and treating piglet pseudoabies, smoothing filter operator, and secondary pig is thermophilic
Application in the herbal medicine of the viruses such as blood bacillus, the infection of bacterium or mixed infection.
Background technology
Chinese herb feed additive is with a long history, and great role is played in pig breeding production.Such as《Compendium of Materia Medica》Just once carry
Arrive：" root of three-nerved spicebush, pig, dog all kinds of diseases and ailments, and can take "；And《Complete ten thousand arts of Huainan》In numb salt dissipate (fructus cannabis 100g, salt 5g) tool
There is moisturize laxation, replenish qi to invigorate the spleen effect, so as to reach the purpose for weightening of fattening.Many Chinese herbal medicines are just used in aquaculture from ancient times,
Because of the unique advantage such as it has vdiverse in function, pollution-free, safe and harmless, economic, sustainable, wide material sources, has no toxic side effect and
Got off by succession.With going deep into for research, it is found that Chinese herb feed additive also has and optimize pig feed quality, improve the productivity of pig
Can, prevention disease, health care, improve swine product quality and other effects.Pig child care stage histoorgan ateliosis, resistance is poor,
Virus, bacteria mixed infection easily occurs.
For these problems, the present invention is by one kind with Yunnan astragalus, and the open country of falling root is revived, evil mind kiss-me, Rhizoma Zingiberis zerumbet, and fruitlet is white
The Chinese medicine composition pierced as raw material is added in the feed of piglet feeding, reaches preventing and treating pseudoabies, PCV-II, the bloodthirsty bar of secondary pig
The infection of bacterium or the effect of mixed infection, moreover it is possible to for piglet health care growth promotion, significant effect.
The content of the invention
It is an object of the present invention to provide a kind of Chinese medicine composition in preparing for the somatotrophic medicine of piglet health care
Purposes；Another object of the present invention is to provide the Chinese medicine composition and is preparing pseudoabies, PCV-II for preventing and treating piglet
Or the purposes in the medicine of infection or the two or more mixed infections of Haemophilus parasuis.
The purpose of the present invention is implemented by following technical measures：
A kind of purposes of Chinese medicine composition in preparing for the somatotrophic medicine of piglet health care；Wherein, the Chinese traditional medicine composition
Thing is made up of the bulk drug of following parts by weight：The parts by weight of Yunnan astragalus 7~21,11~33 parts by weight of the open country of falling root Soviet Union, evil mind tiger ear
Careless 6~18 parts by weight, the parts by weight of Rhizoma Zingiberis zerumbet 9~27, the parts by weight of nitraria schoberi 10~30.
It is preferred that above-mentioned Chinese medicine composition is made up of the bulk drug of following parts by weight：The parts by weight of Yunnan astragalus 8~10, the open country of falling root
13~16 parts by weight of Soviet Union, the parts by weight of evil mind kiss-me 7~9, the parts by weight of Rhizoma Zingiberis zerumbet 10~12, the parts by weight of nitraria schoberi 11~13.
A kind of Chinese medicine composition is used to prevent and treat the pseudoabies of piglet, PCV-II or Haemophilus parasuis in preparation
Purposes in the medicine of infection or two or more mixed infections；Wherein, the Chinese medicine composition by following parts by weight bulk drug system
Into：The parts by weight of Yunnan astragalus 7~21,11~33 parts by weight of the open country of falling root Soviet Union, the parts by weight of evil mind kiss-me 6~18, Rhizoma Zingiberis zerumbet 9~27
Parts by weight, the parts by weight of nitraria schoberi 10~30.
It is preferred that above-mentioned Chinese medicine composition is made up of the bulk drug of following parts by weight：The parts by weight of Yunnan astragalus 8~10, the open country of falling root
13~16 parts by weight of Soviet Union, the parts by weight of evil mind kiss-me 7~9, the parts by weight of Rhizoma Zingiberis zerumbet 10~12, the parts by weight of nitraria schoberi 11~13.
Above-mentioned Chinese medicine composition can be prepared into powder.The Chinese medicine composition adds use in pig starter feed.
Above-mentioned Chinese medicine composition is prepared by the following method to obtain：
By Yunnan astragalus, the open country of falling root Soviet Union, evil mind kiss-me, Rhizoma Zingiberis zerumbet, nitraria schoberi mixing, 7~8 times of amounts of dosing material gross weight
Water soaks 8~12h, boils and maintains 1-2h, filters, and 5~6 times of dosing material gross weight measures water to filter residue again, boils and maintains 0.5-1h,
Filtering, merge filtrate twice, be condensed into medicinal extract.
Above-mentioned traditional Chinese powder medicine is prepared by the following method to obtain：
By Yunnan astragalus, the open country of falling root Soviet Union, evil mind kiss-me, Rhizoma Zingiberis zerumbet, nitraria schoberi mixing, 7~8 times of amounts of dosing material gross weight
Water soaks 8~12h, boils and maintains 1-2h, filters, and 5~6 times of dosing material gross weight measures water to filter residue again, boils and maintains 0.5h-
1h, filtering, merge filtrate twice, concentration, dry, pulverize.
Above-mentioned piglet health care growth promotion Chinese medicine composition adds in feed, reaches growth promotion and can and prevents and treats young pseudorabies
The infectious diseases such as disease, smoothing filter operator, Haemophilus parasuis or the purpose of two or more mixed infections.
Dosage and method：300-700g of the present invention, preferably 500g are added in feed per ton, is well mixed, freely adopts
Food.Said composition solves that Chinese medicine crushed material palatability is poor, addition is big, curative effect is single, it is impossible to adapts to piglet virus, bacterium mixes
Close the deficiency of infection.
Beneficial effects of the present invention：The present invention draws traditional Chinese veterinary medicine marrow；Yunnan astragalus, it is legume Yunnan astragalus
Astragatus yunnanensis Franch. root, function have invigorating qi for strengthening superficies, yang invigorating, torr sore myogenic.Cure mainly weak
Weak, deficiency of food receives difference, protracted dysentery chronic diarrhea, spontaneous sweating, anaemia, oedema, the prolapse of uterus, prolapse of the anus, chronic ulcer.The open country of falling root is revived, and is
Labiate rabdosia japonica Rabdosia japonica (Burm.f.) Hara var glaucocalyx (Maxim) Hara
Herb or leaf.Function has clearing heat and detoxicating, stomach strengthening and digestion promoting.Wrist abdominal distention and pain is cured mainly, food stagnation is indigestion and loss of appetite, hypochondriac pain jaundice, cold, fever, breast
Carbuncle, snake bite and insect sting.Evil mind kiss-me, it is saxifragaceae plant Herba Saxifragae melanocentrae Saxifra melanocentra Franch's
Herb, function have clearing heat and promoting diuresis, activating blood circulation and reducing swelling.Cure mainly jaundice with damp-heat pathogen, traumatic injury, cough, red eye, swell pain, carbuncle sore tumefacting virus.It is red
Ball ginger is zingiberaceous plant Rhizoma Zingiberis zerumbet Zergiber zerumbet (T.) smith. rhizome, and function has promoting blood circulation, and promoting the circulation of qi stops
Bitterly, warming middle energizer to stop diarrhea, consumer product dredge stasis.Cure mainly various hemostasis diseases caused by irritability stasis, energy-stagnation stomachache, diarrhoea, indigestion, food stagnation
Gastral cavilty.Nitraria schoberi is zygophyllaceae plant nitraria schoberi Nitraria sibirica Pall. fruit, and function has strengthening the spleen and stomach,
Replenishing qi and blood.Cure mainly spleen eating less, indigestion, qi-blood deficiency is in poor health.5 kinds of compatibility of drugs, the pseudo- mad dog of piglet can be prevented and treated
Virus, the infection of bacterium or the two or more mixed infections such as disease, PCV-II or Haemophilus parasuis, also growth promotion are made
With, while it is safe to use, have no toxic side effect.
Below further illustrated with regard to effect experiment the effect of of the invention.
First, the present invention is to pig growth promotion feeding experiment
1st, experimental animal：The similar 30 age in days DLYs hybridization wean pig 80 of selection parity, age in days, male and female half and half, with
Machine is divided into 4 groups, every group 20, pre- feeding 10 days, formally starts to test.
2nd, method：4 group basal diets are identical, and the 1st group is added 700 grams of Chinese medicine composition of the present invention in feed per ton
(being prepared by embodiment 1, be set to high dose group), the 2nd group is added 500 grams of Chinese medicine composition of the present invention (by real in feed per ton
Apply example 1 to prepare, be set to middle dose group), the 3rd group is added 300 grams of Chinese medicine composition of the present invention (by embodiment 1 in feed per ton
Prepare, be set to low dose group), the 4th group is only fed basal diet feed (being set to control group), is not added with any medicine.Free water with
Feeding, 40 days experimental periods.Experimental basis feed formula is shown in Table 1
The basal diet feed formula of table 1 and trophic level (%)
3rd, feeding management：
(1) sterilize：Before being enclosed in test pig, colony house is sterilized with 10% Betagen Solution, and test pig body surface is new clean with 0.1%
You go out sterilization.
(2) trial test：After test pig packet, start prerun, 10 days preliminary trial periods, feed and formal examination on March 9th, 2017
The feed tested is identical.
(3) formal test：On March 19th, 2017, morning 7:00 claims initial weight, morning 7 on April 18th, 2017 on an empty stomach:00 is empty
Abdomen claims end weight, totally 40 days, accurate recording feed intake, the situation such as the spirit of pig, fur, excrement, breathing.
(4) for test pig under identical feeding and management condition, special messenger is responsible for record data.
4th, content is tested：Weightening, feed consumption, feedstuff-meat ratio, health status, specific data are shown in Table 2.Taken a blood sample before off-test, point
From serum, total protein, albumin, globulin content in serum are determined, the XD811 of medical instrument companies' production is reached using upper Hisoon
Semi-automatic biochemical analyzer, using scattering speed turbidimetry for Determination, measure kit is purchased from health Bioisystech Co., Ltd of Erie,
Serum Indexes measurement result is shown in Table 3.
Diarrhoea criterion：Every morning 8:00 timing observation piglet excrement situation, excrement be divided into normal, loose stool, it is sticky,
5 grades of water sample and bloody stool, rear 4 grades are judged to suffer from diarrhoea.
Test data sheet：Every group of diarrhea of pigs head is recorded, calculates diarrhea rate (diarrhea rate=diarrhoea piglet head/total head of piglet
Number)
Influence of the compound traditional Chinese medicine composite of table 2 to Production Performance of Weaning Pigs
Note：Compared with control group, * ﹤ 0.05.
From table 2, middle dose group effect is best, improves 20.53% than control group daily gain, significant difference (P ﹤
0.05), diarrhea rate declines 68.29% (P ﹤ 0.05).High dose group, low dose group are respectively increased than control group daily gain
6.86%th, 9.77%, difference is not notable (P ﹥ 0.05).Diarrhea rate declines 63.41% significant difference (P ﹤ 0.05), 21.95%, poor
Different not notable (P ﹥ 0.05).
Influence of the compound traditional Chinese medicine composite of table 3 to piglet haemocyanin index
Note：Compared with control group, * ﹤ 0.05
From table 3 it can be seen that compared with control group, compound traditional Chinese medicine composite high dose group total protein, albumin, globulin
13.81%, 12.42%, 15.35% is respectively increased, difference is not notable (P ﹥ 0.05).Compound traditional Chinese medicine composite middle dose group is distinguished
29.88%, 33.81%, 15.27% is improved, difference is extremely significantly (P ﹤ 0.01).Compound traditional Chinese medicine composite low dose group is respectively increased
11.63%th, 7.45%, 15.27%, difference is not notable (P ﹥ 0.05).Haemocyanin improves, display body's resistance to disease enhancing.
2nd, the external resisting pstudorabies Viral Assay research of the present invention
1st, the age in days of chicken embryo 10 is non-exempts from chicken embryo for experiment, is purchased from emerging great Hua Nong birds, beasts and eggs Co., Ltd.
2nd, pseudorabies sickly look A strains AV25 strains are provided by China Veterinery Drug Inspection Office, strain normal saline dilution,
Be inoculated with it is non-exempt from chicken embryo, collect allantoic fluid, be for experiment.The HA potency of chick embryo allantoic liquid is 7log2。
3rd, this experiment of medicine is using the present composition as test drug；Ribavirin injection is that Western medicine compares medicine, by
The favorable to the people pharmaceutical Co. Ltd's production in Jinan, is made into 0.05g/mL concentration.Tannic acid is produced by Shanghai Ling Feng chemical reagent Co., Ltd.
4th, the preparation adult Balb/c mouse of experimental animal and red blood cell, are purchased from south China agricultural university animal experimental center.It is red thin
The preparation of born of the same parents：Eyeball of mouse is cut off with eye scissors, exposure optical fundus blood vessel, few drops is taken a blood sample in the centrifuge tube added with anti-coagulants, uses
PBS is washed 3 times, is then made into 10% red blood cell with PBS, is uniformly mixed in equal volume with 1/40000 concentration tan-liquor, in 37 DEG C
Effect centrifuges for 1 hour, then wash 3 times, is centrifuged with 1500r/min, each 5min with PBS, add during use PBS be made into 1% it is red carefully
Born of the same parents' suspension.
5th, experiment packet 40 pieces of instar chicken embryo on the 10th, is randomly divided into 4 groups, specific packet situation is shown in Table 4.
The chicken embryo of table 4 is grouped situation
6th, test method
(1) viral allantoic fluid is diluted different multiples by median lethal dose measure, and inoculation is non-to exempt from chicken embryo, show that embryo's half causes
Dead amount.By measure, the dilution factor of chicken embryo virus allantoic fluid median lethal dose is 1: 50, and formal test is inoculated with dilution factor with 1: 25
Allantoic fluid.
(2) toxicity trial Chinese medicine original liquid physiological saline makees doubling dilution, by Chinese medicine stoste and various concentrations
Decoction is inoculated in 3 piece of 10 age in days chick embryo allantoic cavity respectively, every 0.2mL, puts 37.8 DEG C of incubations 72 hours, observation daily
Survival condition, the highest liquor strength that chicken embryo is all survived is formal test initial concentration, while sets saline control group, medicine
Thing is shown in Table 5 to embryonic toxicity result of the test.
The Chinese medicine of table 5 is to embryonic toxicity experimental result (n=4)
★ denominators are inoculation embryo number, and molecule is survival embryo number.
(3) inhibitory action that medicine of the present invention is bred to porcine pseudorabies virus is determined with 1：The dilution factor of 25 allantoic fluids and
Foundation of the drug concentration of table 2 as inoculation.Specific method is as follows.
Test I group of each chick embryo allantoic cavity while be inoculated with medicine of the present invention and (be prepared 1 by the method for embodiment 1:5 dilutions
Stoste) 0.2mL, viral dilution liquid 0.1mL.
Test II group of each chick embryo allantoic cavity while meet Ribavirin 0.2mL, viral dilution liquid 0.1mL.
Test III group of each chick embryo allantoic cavity while be inoculated with physiological saline 0.2mL, viral dilution liquid 0.1mL.
IV group of blank control group is tested, virus inoculation, is not administered.
Above-mentioned chicken embryo is incubated in 37.8 DEG C of insulating boxs, shines egg daily 2~3 times, discards dead germ in 24 hours.It is small to collect 72
Shi Yihou work embryo and 24~72 hours dead germ allantoic fluids, Cord blood are standby.With every group of chicken embryo urine of blood clotting (HA) testing inspection
The virus titer of cyst fluid.
7th, the inhibitory action that Chinese medicine is bred to porcine pseudorabies virus
Dead 1 piece at 24~72 hours of Ith group of chicken embryo, survive 9 pieces within 72 hours, collect 1 piece of dead chicken embryo and 9 pieces of survivals
Chick embryo allantoic liquid, HA titres be 0.
Dead 10 pieces at 24~72 hours of IIth group of chicken embryo, 72 hours without survival, the allantoic fluid of 10 pieces of dead germs of collection, HA drops
Spend for 6log2。
Dead 10 pieces at 24~72 hours of IIIth group of chicken embryo, 10 pieces of dead germ allantoic fluids are collected, HA titres are 8log2。
IVth group in 72 hours without chicken embryo death, collect all embryo allantoic liquids living, HA titres are 0, and detailed results are shown in Table
6。
The inhibitory action measurement result that the Chinese medicine of table 6 is bred to porcine pseudorabies virus
Compared with the IIIth group, * * P ＜ 0.01
3rd, the present invention is to virus and the prevention result of bacteria mixed infection
Jiangsu Taizhou Xinghua pig farm, feeding mother pig, on October 10th, 2016, weanling pig 320 is not bought back from market,
It is divided into 2 groups, the 1st group of 200 piglets, is added after buying back with Chinese medicine composition of the present invention (being prepared by embodiment 2) in feed per ton
Add 500 grams of progress health cares, buy back 30 days, observation swinery is more stable always daily, without any abnormal appearance.2nd group of 120 sons
Pig Amoxicillin health care, feed per ton add 750 grams, and since October 15, the 2nd group had indivedual temperature of pig body to rise to 40.6 DEG C
Left and right, there is spiritual depressed, anorexia.October 19, full mass-sending disease, performance breathe fast, rubefaction, diarrhoea, groin
Enlargement of lymph nodes.Cut open inspection 4；Cut open inspection changes：The visible hydropericardium of sick pig cut open inspection；Lymph nodes of body as a whole enlargement, particularly groin
Lymph node and submandibular lymph nodes, section are turned up, and have weak yellow liquid outflow；Lungs are in diffusivity interstitial pneumonia, have part be in
Pancreas sample meat becomes；Hydroabdomen, each internal organs adhesion, has albumen to ooze out；The slight enlargement of spleen, kidney is pale, and quality becomes fragile, Ge Bieyou
Tip-like blutpunkte；There is part pig liver enlargement, yellow is presented；There is part pig stomach mucous membrane ulcer occur；Arthroedema has light
Yellow liquid oozes out.
Laboratory diagnosis
1st, Viral diagnosis：Collection sick dead pig pathological material of disease is sent to Yangzhou University and carries out Pathogen test, have detected pig circular ring virus 2 respectively
Malicious 2 types (PCR method), porcine reproductive and respiratory syndrome virus (RT-PCR method), PRV (PCR method), swine fever
Viral (RT-PCR method), as a result only detection has PCV-II, and other viruses do not detect.
2nd, bacteriodiagnosis
(1) Bacteria Culture is sterile takes sick pig lungs, joint fluid, chambers of the heart hydrops and cardiac blood to be inoculated in TSA (to contain 5% calf
Cow's serum, 0.005%NAD) solid medium, it is inverted in culture 36h~48h in 37 DEG C of incubators.Bacterium colony on solid medium
Form for circle, grey, it is translucent, it is smooth moisten, tip-like size；Bacterium is through Gram's staining, visible list under microscope
Individual rod-short or the gramnegative bacterium of short chain shape.
(2) bacteria bio experiment intersects on sheep blood agar plate with staphylococcus first to the bacterium isolated and purified
Line, the hemolytic of its NAD dependence of culture identification, reselection is dependent on NAD but the progress of the bacterium without hemolytic is other
Biochemical identification.Every biochemical identification result meets the feature of haemophilus parasuis reference culture, as a result shows that the separation is thin
Bacterium is haemophilus parasuis.
3rd, treatment：It is dead to October 29 with Florfenicol and Effect of APS in Treating after 2nd group of 120 pigs morbidity
58, the death rate 48.3%, cause very big economic loss.
4th, safety testing
For the toxic side effect of Chinese medicine composition clearly of the present invention, and accurate, objective appraisal is made to its security, be
Clinical application provides scientific basis, it is ensured that drug safety, has carried out the toxicity test of the Chinese medicine composition.
Acute toxicity test：By (being prepared by embodiment 2) LD that Chinese medicine composition is carried out to ICR mouse50Most
Big tolerance test shows that after dosage is designed by oral administration, each group mouse behavior sign is normal in 8 days, does not occur nosotoxicosis
Shape and death.Therefore LD can not be determined50, and have to be using maximum dosage-feeding 60g/kg as maximum dose level.After 10th day slaughters, each group
The internal organs such as the liver,kidney,spleen of mouse, lung are without lesion.
Long term toxicity test：From SD rats 24, it is divided into 3 groups, every group 8, male and female half and half, gives various dose
The Chinese medicine preparation (being prepared by embodiment 1) of the invention of (30.0,15.0,7.5g crude drugs/kg), daily perfusion once, even
It is continuous 30 days.Three dosage group animal animations of the present invention are good, appearance sign, behavioral activity, food-intake and body weight increase
Change without exception.The internal organs such as the liver,kidney,spleen of each group rat, lung are without lesion.Show the Chinese medicine composition have no toxic side effect and
Adverse reaction, clinical practice are safe and reliable.
Embodiment
With reference to specific embodiment, the invention will be further described：
Embodiment 1
Prescription：Yunnan astragalus 9g, the open country of falling root Soviet Union 13g, evil mind kiss-me 8g, Rhizoma Zingiberis zerumbet 11g, nitraria schoberi 12g.
Specific preparation process is as follows：
By Yunnan astragalus, the open country of falling root Soviet Union, evil mind kiss-me, Rhizoma Zingiberis zerumbet, nitraria schoberi mixing, add up medicinal material and weigh 7 times of water loggings
10h is steeped, 1h is maintained after boiling, is filtered, filter residue adds up medicinal material and weighs 5 times of water again, and 30min is maintained after boiling, and filtrate merges twice,
The medicinal extract that density is 1.15 is obtained after 90 DEG C of condition concentrations, dry cream is dried to obtain, crushes and produce powder.
Embodiment 2
Prescription：Yunnan astragalus 8g, the open country of falling root Soviet Union 16g, evil mind kiss-me 7g, Rhizoma Zingiberis zerumbet 12g, nitraria schoberi 11g.
Specific preparation process is as follows：
By Yunnan astragalus, the open country of falling root Soviet Union, evil mind kiss-me, Rhizoma Zingiberis zerumbet, nitraria schoberi mixing, add up medicinal material and weigh 8 times of water loggings
12h is steeped, 1h is maintained after boiling, is filtered, filter residue adds up medicinal material and weighs 6 times of water again, and 30min is maintained after boiling, and filtrate merges twice,
The medicinal extract that density is 1.15 is obtained after 90 DEG C of condition concentrations, dry cream is dried to obtain, crushes and produce powder.
Embodiment 3
Prescription：Yunnan astragalus 14g, the open country of falling root Soviet Union 22g, evil mind kiss-me 12g, Rhizoma Zingiberis zerumbet 18g, nitraria schoberi 20g.
Specific preparation process is as follows：
By Yunnan astragalus, evil mind kiss-me, Rhizoma Zingiberis zerumbet, nitraria schoberi mixing, add up medicinal material and weigh 7 times of water immersion 10h, boil
After maintain 1h, filter, filter residue adds up medicinal material and weigh 5 times of water again, and 30min is maintained after boiling, and filtrate merges twice, dense in 90 DEG C of conditions
The medicinal extract that density is 1.15 is obtained after contracting, dry cream is dried to obtain, crushes and produce powder.
Embodiment 4
Prescription：Yunnan astragalus 21g, the open country of falling root Soviet Union 33g, evil mind kiss-me 16g, Rhizoma Zingiberis zerumbet 27g, nitraria schoberi 30g.
Specific preparation process is as follows：
By Yunnan astragalus, the open country of falling root Soviet Union, evil mind kiss-me, Rhizoma Zingiberis zerumbet, nitraria schoberi mixing, add up medicinal material and weigh 8 times of water loggings
8h is steeped, 1.5h is maintained after boiling, is filtered, filter residue adds up medicinal material and weighs 6 times of water again, and 1h is maintained after boiling, and filtrate merges twice, 90
The medicinal extract that density is 1.15 is obtained after the concentration of DEG C condition, (first begin to rehearse blower fan, then opens air inlet fan for spray drying.Then steam is opened
Valve, when waiting that temperature is to 110 DEG C in tower, open high pressure homogenizer and dusted), produce powder.
Claims (8)
- A kind of 1. purposes of Chinese medicine composition in preparing for the somatotrophic medicine of piglet health care；Wherein, the Chinese medicine composition It is made up of the bulk drug of following parts by weight：The parts by weight of Yunnan astragalus 7~21,11~33 parts by weight of the open country of falling root Soviet Union, evil mind kiss-me 6 ~18 parts by weight, the parts by weight of Rhizoma Zingiberis zerumbet 9~27, the parts by weight of nitraria schoberi 10~30.
- 2. purposes according to claim 1, it is characterised in that the Chinese medicine composition is made up of the bulk drug of following parts by weight： The parts by weight of Yunnan astragalus 8~10,13~16 parts by weight of the open country of falling root Soviet Union, the parts by weight of evil mind kiss-me 7~9, the weight of Rhizoma Zingiberis zerumbet 10~12 Measure part, the parts by weight of nitraria schoberi 11~13.
- 3. a kind of Chinese medicine composition is preparing the sense of the pseudoabies, PCV-II or the Haemophilus parasuis that are used for preventing and treating piglet Purposes in dye or the medicine of two or more mixed infections；Wherein, the Chinese medicine composition is made up of the bulk drug of following parts by weight： The parts by weight of Yunnan astragalus 7~21,11~33 parts by weight of the open country of falling root Soviet Union, the parts by weight of evil mind kiss-me 6~18, the weight of Rhizoma Zingiberis zerumbet 9~27 Measure part, the parts by weight of nitraria schoberi 10~30.
- 4. purposes according to claim 3, it is characterised in that the Chinese medicine composition is made up of the bulk drug of following parts by weight： The parts by weight of Yunnan astragalus 8~10,13~16 parts by weight of the open country of falling root Soviet Union, the parts by weight of evil mind kiss-me 7~9, the weight of Rhizoma Zingiberis zerumbet 10~12 Measure part, the parts by weight of nitraria schoberi 11~13.
- 5. the purposes according to claim 1 or 3, it is characterised in that the Chinese medicine composition is prepared into powder.
- 6. the purposes according to claim 1 or 3, it is characterised in that the Chinese medicine composition is to be prepared by the following method to obtain 's：By Yunnan astragalus, the open country of falling root Soviet Union, evil mind kiss-me, Rhizoma Zingiberis zerumbet, nitraria schoberi mixing, 7~8 times of amount water loggings of dosing material gross weight 8~12h is steeped, boils and maintains 1-2h, is filtered, 5~6 times of dosing material gross weight measures water to filter residue again, boils and maintains 0.5-1h, mistake Filter, merge filtrate twice, be condensed into medicinal extract.
- 7. purposes according to claim 5, it is characterised in that the traditional Chinese powder medicine is prepared by the following method to obtain：By Yunnan astragalus, the open country of falling root Soviet Union, evil mind kiss-me, Rhizoma Zingiberis zerumbet, nitraria schoberi mixing, 7~8 times of amount water loggings of dosing material gross weight 8~12h is steeped, boils and maintains 1-2h, is filtered, 5~6 times of dosing material gross weight measures water to filter residue again, boils and maintains 0.5-1h, mistake Filter, merge filtrate twice, concentration, dry, pulverize.
- 8. the purposes according to claim 1 or 3, it is characterised in that the Chinese medicine composition adds use in pig starter feed.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107929426A (en) * | 2017-12-11 | 2018-04-20 | 河南惠通天下生物工程有限公司 | A kind of herbal medicine of removing dampness to stop itchin and preparation method thereof |
| CN109394859A (en) * | 2018-10-15 | 2019-03-01 | 江苏农牧科技职业学院 | The pharmaceutical composition and its preparation method and application for preventing and treating Haemophilus parasuis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075241A (en) * | 2016-08-04 | 2016-11-09 | 江苏农牧科技职业学院 | A kind of piglet health care growth promotion Chinese medicine composition and preparation method thereof |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075241A (en) * | 2016-08-04 | 2016-11-09 | 江苏农牧科技职业学院 | A kind of piglet health care growth promotion Chinese medicine composition and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107929426A (en) * | 2017-12-11 | 2018-04-20 | 河南惠通天下生物工程有限公司 | A kind of herbal medicine of removing dampness to stop itchin and preparation method thereof |
| CN109394859A (en) * | 2018-10-15 | 2019-03-01 | 江苏农牧科技职业学院 | The pharmaceutical composition and its preparation method and application for preventing and treating Haemophilus parasuis |
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Application publication date: 20171124 |