CN107753568A - A kind of Chinese medicine composition for being used to prevent and treat poultry proventriculitis, ventriculitis - Google Patents

A kind of Chinese medicine composition for being used to prevent and treat poultry proventriculitis, ventriculitis Download PDF

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Publication number
CN107753568A
CN107753568A CN201610693465.9A CN201610693465A CN107753568A CN 107753568 A CN107753568 A CN 107753568A CN 201610693465 A CN201610693465 A CN 201610693465A CN 107753568 A CN107753568 A CN 107753568A
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parts
medicine composition
ventriculitis
chinese medicine
chinese
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王晓宇
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SHENYANG VICA ANIMAL HUSBANDRY TECHNOLOGY Co Ltd
Beijing Wik Biotechnology Ltd By Share Ltd
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SHENYANG VICA ANIMAL HUSBANDRY TECHNOLOGY Co Ltd
Beijing Wik Biotechnology Ltd By Share Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
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  • Microbiology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to a kind of Chinese medicine composition for being used to prevent and treat chicken proventriculitis, ventriculitis, its raw material composition is in parts by mass:2 10 parts of corydalis tuber, 15 parts of elecampane, 15 parts of sea Piao sheath, 16 parts of alumen, 15 parts of Divine Comedy, 15 parts of radix glycyrrhizae, can be prepared as powder and granule two-form.The Chinese traditional medicine composition is chosen cuttlebone, alumen, the taste medicine of Divine Comedy 3 and relieved pain with reaching relieving haperacidity, hemostasia and promoting granulation, the helping that help digestion work(, choose elecampane, the taste medicine of corydalis tuber 2 makees strengthening the spleen and stomach, regulating the qi flowing in the channels and the effect of blood, then select and relieving spasm to stop pain is played with radix glycyrrhizae, the drug effect that reconciles is used, all medicines share, for preventing and treating the effect of chicken proventriculitis, ventriculitis.This Chinese traditional medicine composition, through clinical case application verification, the effect treated both principal and secondary aspect of disease, drug residue free can be arrived in preventing and treating chicken proventriculitis, ventriculitis disease.This Chinese traditional medicine composition has, pure Chinese medicinal preparation, definite effect, and drug residue free, technique are simple, and cost is cheap, it is easy to spread the advantages that.

Description

A kind of Chinese medicine composition for being used to prevent and treat poultry proventriculitis, ventriculitis
Technical field:
The invention belongs to veterinary drug technology and application field, is related to a kind of drug regimen, and chicken proventriculitis is prevented and treated more particularly, to one kind Drug regimen.
Technical background:
In recent ten years, chicken ventriculitis and proventriculitis are constantly popular in China, and this disease is with being concentrated mainly on northeast, North China and Central China Area, have become and endanger one of most commonly seen disease of poultry farming production.Several years ago morbidity is concentrated mainly on weather more Warm up hot season, nearly 2 years extents of injury are incremented by, are continued until that winter is also falling ill, huge damage is caused to aquaculture Lose.
The gland ventriculitis of poultry be it is a kind of with poultry undergrowth, become thin, regularity it is poor, the outward appearance such as punishment in advance symptom, glandular stomach Enlargement, or glandular stomach applanation nipple even disappear, and glandular stomach mucosa hemorrhage ulcer, come off, gold and muscular stomach mucosal surface volcanic crater in muscular stomach Sample ulcer, gizzard erosion be principal character epidemic disease, the disease morbidity morning, easily repeatedly, preclinical symptom unobvious, the later stage because The multiple organ failures of internal organ and it is dead, and serious growth inhibition is presented in the chicken of resistance to mistake, occurs a large amount of " stiff chickens ".
The sick clinical symptoms, pathological change are not quite similar, and cause of disease is had different versions.The cause of disease is complicated, by ambient humidity, The many factors such as feed mould, virus, bacterium act on the change that result in glandular stomach structure and function, but nearly all generation glandular stomach Virus can be isolated in scorching chicken group, therefore fixes tentatively entitled " viral proventriculitis ", also referred to as " Glandular Stomach Type passes branch ".Due to the cause of disease Complexity, is difficult to receive effective using antibiotic medication, and easily chicken group is produced drug resistance, the treatment production for other diseases It is raw to influence, if proventriculitis chicken group, followed by other infection other diseases, or even the possibility for having full group to eliminate is sent out, antibiotic is indiscriminate in addition With medicament residue is caused, human health is endangered.
The content of the invention:
After based on being analyzed and researched on the basis of traditional Chinese medicine theory to gland ventriculitis, in line with sample The simultaneous principle controlled prescription again.This prescription is pure Chinese medicinal preparation, can prevent and treat poultry proventriculitis, ventriculitis disease, preparation technology letter It is single, easily realize, and also had great significance to reducing the use of antibiotic and medicament residue in breeding production.
The present invention solve its technical problem technical scheme be:
A kind of preventing and treating poultry proventriculitis, the Chinese medicine composition of ventriculitis, are prepared by the composition of following weight parts:Corydalis tuber 2- 10 parts, elecampane 1-5 parts, sea Piao sheath 1-5 parts, alumen 1-6 parts, Divine Comedy 1-5 parts, radix glycyrrhizae 1-5 parts.
Preferably, Chinese medicine composition is told, is prepared by the composition of following weight parts:Corydalis tuber 2-6 parts, elecampane 2- 4 parts, sea Piao sheath 2-40- parts, alumen 2-5 parts, Divine Comedy -2-4 parts, radix glycyrrhizae 2-4 parts.
It is further preferred that told Chinese medicine composition, is prepared by the composition of following weight parts:4 parts of corydalis tuber, building Fragrant 2 parts, 2 parts of sea Piao sheath, 3 parts of alumen, 2 parts of Divine Comedy, 2 parts of radix glycyrrhizae.
Told Chinese medicine meets《Chinese veterinary pharmacopoeia》The ministerial standard of version second in 2010.
According to Chinese medicine Historical Data Data About, 6 taste Chinese medicines of appeal have following major function:
Corydalis tuber:Acrid flavour is bitter and warm-natured, and Wen Tongshan is walked.Enter the heart, Liver Channel, the main blood of the heart, firm store blood and walk blood system, enter spleen, lung channel, spleen Main transporting, lung governing qi and walk qi leel, therefore can warm walk help gas and and blood, the stagnation of the circulation of vital energy in promoting circulation of blood, vim and vigour no pain by smooth breath, have blood-activating and qi-promoting The work(of analgesic.The pungent scattered hardship of corydalis tuber is let out, and is had brokenly silt among promoting blood circulation concurrently and is used, and for hematogenous blockage, stagnates cohesion, or blood circulating out of vessels Product influences the syndrome of blood stasis of QI-blood circulation, the effect of tool promoting blood circulation scattered silt in internal.
Elecampane:Acrid flavour gas fragrance temperature, pungent fragrant energy dampness elimination promoting the circulation of qi, gas row is stagnant to disappear, and pain then from only, temperature energy cold dispelling, enters the spleen channel There are invigorating the spleen middle benefit gas, the work(of the cold dehumidifying of Eradicates.
Sea Piao sheath:Taste is salty, puckery, gas tepor, can hold back acid and stomach, relieving haperacidity analgesic, light such as powder, orally enter stomach, directly become impaired To blood network, its puckery property held back is taken, blood vessels is restrained, stops blooding because of puckery blood circulating out of vessels;With its saline taste, softening and resolving hard mass becomes silted up without staying, and is Control hyperhydrochloria, astringing to arrest bleeding to good medicine.
Alumen:Puckery acid cold, enter liver taste warp can be clearing heat and detoxicating, if pyosis, can let out meat corruption purulence, new flesh growth.
Divine Comedy:It is sweet, pungent, it is warm-natured.Returns spleen, stomach.Gas fragrance and, can rise to drop.Promoting digestion and removing indigestion, strengthening the spleen and stomach, inducing diaphoresis. Cure mainly flu food stagnation, epigastric distension and distress, indigestion, diarrhoea., get ill from overeating stagnant, infantile malnutrition incoordination between the spleen and the stomach in general also has treatment Effect.Divine Comedy is pungent sweet warm-natured, and the power to help digestion is relatively strong and invigorating and regulating stomach, the disease suitable for various dyspepsias.
Radix glycyrrhizae:It is sweet, it is mild-natured, it is nontoxic, it is sweet can emergency, enter taste warp, the main four limbs of taste and placed in the middle burnt, sweet temperature QI invigorating are delayed Anxious analgesic, mild in medicine property and, pass through the twelve regular channels, and can rise to drop, and can delay, solve but also mend not only, there is the effect of mediation property of medicine.
Composition principle:
The traditional Chinese medical science is to stress the dynamic of syndrome characteristics, to adjust the balance that body internal organs reach function.From chicken proventriculitis, ventriculitis Symptom analysis, the unbalance crux of body is looked for, is deficiency-weakness of spleen-QI, to failure of the spleen to transport and transform, indigestion, the dysfunction of the spleen in transport and the wet difficulty of water Under, moisture is trapped in middle Jiao, dysfunction of the spleen health, and mechanism of qi is obstructed, damp evil perfusion stomach, long and cause glandular stomach, muscular stomach, enteron aisle ulcer, Inflammation.
Analyzed more than, draft prescription.Cuttlebone, alumen, the taste medicine of Divine Comedy 3 are chosen to reach relieving haperacidity analgesic, hemostasis is given birth to Flesh, the helping that help digestion work(, choose elecampane, the taste medicine of corydalis tuber 2 and make the effect of strengthening the spleen and stomach, regulating the qi flowing in the channels and blood, then select and risen with radix glycyrrhizae To relieving spasm to stop pain, the drug effect that reconciles is used, and all medicines share, plays the effect treated both principal and secondary aspect of disease altogether.
The Chinese medicine composition, powder or granule can be made.
Traditional Chinese powder medicine, by spice feed for poultry, to prevent fowl proventriculitis, the ventriculitis of managing a household.
Granule, by spice feed for poultry, to prevent fowl proventriculitis, the ventriculitis of managing a household.
It is of the present invention be used for prevent and treat poultry proventriculitis, the Chinese traditional medicine composition of ventriculitis has the advantage that:
(1)We, from outward appearance to inner essence for foundation, are controlled expression and relieved pain to relieving haperacidity, hemostasia and promoting granulation, the work(for the helping that help digestion, controlled with theory of traditional Chinese medical science Originally the effect of strengthening the spleen and stomach, regulating the qi flowing in the channels and blood is reached, to reach the fruit of preventing and treating ventriculitis, proventriculitis.
(2)Chinese traditional medicine composition disclosed by the invention is prepared by 6 taste Chinese medicines, and raw material is easy to get, technique simply for cost compared with It is low, it is easy to spread.
(3)We are pure Chinese medicinal preparation, significant to the use of reduction antibiotic and medicament residue in breeding production.
Embodiment:
The present invention is described in further detail by following embodiment.It should be noted that:Following embodiments are illustrative, are not limits Qualitatively, it is impossible to limit protection scope of the present invention with following embodiments.All changes or equivalent without departing substantially from present inventive concept Replacement is included within protection scope of the present invention.
The formula of the Chinese traditional medicine composition of embodiment 1
Chinese medicine composition is prepared by the composition of following parts by weight:2 parts of corydalis tuber, 1 part of elecampane, 1 part of sea Piao sheath, alumen 1 Part, 1 part of Divine Comedy, 1 part of radix glycyrrhizae.
Or Chinese medicine composition is prepared by the composition of following parts by weight:10 parts of corydalis tuber, 5 parts of elecampane, sea Piao sheath 5 Part, 6 parts of alumen, 5 parts of Divine Comedy, 5 parts of radix glycyrrhizae.
Or Chinese medicine composition is prepared by the composition of following parts by weight:6 parts of corydalis tuber, 4 parts of elecampane, sea Piao sheath 4 Part, 5 parts of alumen, 4 parts of Divine Comedy, 4 parts of radix glycyrrhizae.
Or Chinese medicine composition is prepared by the composition of following parts by weight:4 parts of corydalis tuber, 3 parts of elecampane, sea Piao sheath 3 Part, 4 parts of alumen, 3 parts of Divine Comedy, 3 parts of radix glycyrrhizae.
The preparation of the powder of embodiment 2
Traditional Chinese powder medicine is made up of agents:4 parts of corydalis tuber, 2 parts of elecampane, 2 parts of sea Piao sheath, 3 parts of alumen, 2 parts of Divine Comedy, radix glycyrrhizae 2 parts.Each ratio of each taste Chinese medicine is parts by weight.Each taste Chinese medicine is mixed and is crushed to and can cross 60 mesh sieves, then by institute There is the traditional Chinese medicine fine powder to pulverize and sieve to be well mixed, dispense, produce.Prepare complete powder, general spice feed in poultry to prevent Control proventriculitis, ventriculitis.
It is prepared by the granule of embodiment 3
Chinese herbal granules are made up of agents:It is 4 parts of corydalis tuber, 2 parts of elecampane, 2 parts of sea Piao sheath, 3 parts of alumen, 2 parts of Divine Comedy, sweet 2 parts of grass.Each ratio of each taste Chinese medicine is parts by weight, and each Chinese medicine is added into 10 times of amounts(Weight ratio)It is standby.By cuttlebone, withered Alum, Divine Comedy co-grinding remix uniform resulting mixture 1 to 60 mesh sieves are crossed, standby;By corydalis tuber, elecampane, radix glycyrrhizae with 60% Ethanol solution, by 10 times, 8 times, 8 times of refluxing extractions 3 times, 60 minutes every time, extract solution filtering and concentrating added mixing to appropriate Thing 1 and appropriate amount of auxiliary materials, pelletize, drying, it is 1kg/kg that crude drug content, which is made, dispenses and produces.The granule completed is prepared, spice is raised Feed in poultry to prevent and treat proventriculitis, ventriculitis, and accumulating is convenient.
The 4 clinical test of pesticide effectiveness of example
1. materials and methods
1.1 experimental animal:
1.1.1 22 Day-old Broiler Chickens 4000 for suffering from ventriculitis, proventriculitis with a hen house are selected
1.1.2 morbidity chicken public sentiment condition and diagnosis:Diseased chicken situation is that infected animal disease time is 22 ages in days, clinical and cut open inspection disease Shape meets proventriculitis, muscular stomach inflammation.
1.2 medicine:
Traditional Chinese powder medicine:The traditional Chinese powder medicine prepared by embodiment 1;
Chinese herbal granules:The middle granule prepared by embodiment 2;
Positive control medicine:Amoxicillin pulvis, Cimetidine pulvis;
1.3 test methods and packet
4000 broiler chicken are divided into 4 groups, every group 1000, are respectively:
1 group of traditional Chinese powder medicine group, dosage are per 2g spice 1kg, 1 time a day, are used in conjunction 5 days;
2 groups of Chinese herbal granules groups, dosage are per 2g spice 1kg, 1 time a day, are used in conjunction 5 days;
3 groups of positive controls, Amoxicillin pulvis, Cimetidine powder according to explanation spice administration, 1 time a day, are used in conjunction 5 days;
4 groups of blank control groups, do not give drug therapy.
Each group test chicken group is observed daily after the administration of 1.4 deliberated indexs, observation diseased chicken feed intake, death toll, cutd open Inspection change, Continuous Observation 5 days.
After 1.5 efficacy determination medications, feed intake rises, and death toll declines, and is determined as that medicine is effective.
2. experimental result
The each group drug therapy situation of table 1
The result of the test of form 1 is analyzed, it may be said that the traditional Chinese powder medicine and Chinese herbal granules of the bright embodiment of the present invention 1,2 are controlled It is extremely obvious to treat proventriculitis, the effect of ventriculitis difference compared with control group, and is also substantially better than positive controls.
Finally it should be noted that:Above example only not limits technology described in the invention to illustrate the present invention Scheme;Therefore, although description of the invention with reference to above-mentioned each embodiment to present invention has been detailed description, It is, it will be understood by those within the art that, still the present invention can be modified or equivalent substitution;And all do not take off Technical scheme and its improvement from the spirit and scope of the present invention, it all should cover among scope of the presently claimed invention.

Claims (5)

  1. A kind of 1. Chinese medicine composition for being used to prevent and treat poultry proventriculitis, ventriculitis, it is characterised in that:The Chinese medicine composition is by following The composition of parts by weight is prepared:Corydalis tuber 2-10 parts, elecampane 1-5 parts, sea Piao sheath 1-5 parts, alumen 1-6 parts, Divine Comedy 1-5 Part, radix glycyrrhizae 1-5 parts.
  2. 2. Chinese traditional medicine composition according to claim 1, its feature from being, the Chinese medicine composition by following weight parts composition It is prepared, corydalis tuber 2-6 parts, elecampane 2-4 parts, sea Piao sheath 2-4 parts, alumen 2-5 parts, Divine Comedy -2-4 parts, radix glycyrrhizae 2-4 parts.
  3. 3. Chinese medicine composition according to claim 1 or 2, its feature is that the Chinese medicine composition is by following weight parts certainly Composition be prepared:4 parts of corydalis tuber, 2 parts of elecampane, 2 parts of sea Piao sheath, 3 parts of alumen, 2 parts of Divine Comedy, 2 parts of radix glycyrrhizae.
  4. 4. according to the Chinese medicine composition described in claim 1-3 any one, its feature is that the Chinese traditional medicine composition can be prepared as certainly Powder and granule.
  5. 5. for preventing and treating application of the Chinese medicine composition of poultry proventriculitis, ventriculitis in preventing and treating poultry proventriculitis, ventriculitis.
CN201610693465.9A 2016-08-22 2016-08-22 A kind of Chinese medicine composition for being used to prevent and treat poultry proventriculitis, ventriculitis Pending CN107753568A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111012827A (en) * 2020-01-10 2020-04-17 河南天昊鸿发生物技术有限公司 Traditional Chinese medicine composition and medicine composition for treating proventriculitis and myogastritis of poultry as well as preparation method and application of traditional Chinese medicine composition and medicine composition

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103860890A (en) * 2012-12-13 2014-06-18 辽宁农业职业技术学院 Traditional Chinese medicine for treating chicken proventriculitis and ventriculitis
CN105250972A (en) * 2015-11-16 2016-01-20 汪鲲 Traditional Chinese medicine composition for preventing and treating poultry proventriculitis and preparation method and application thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103860890A (en) * 2012-12-13 2014-06-18 辽宁农业职业技术学院 Traditional Chinese medicine for treating chicken proventriculitis and ventriculitis
CN105250972A (en) * 2015-11-16 2016-01-20 汪鲲 Traditional Chinese medicine composition for preventing and treating poultry proventriculitis and preparation method and application thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
肖延仁等: "肉鸡腺肌胃炎中医辨证分析及诊治", 《今日畜牧兽医》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111012827A (en) * 2020-01-10 2020-04-17 河南天昊鸿发生物技术有限公司 Traditional Chinese medicine composition and medicine composition for treating proventriculitis and myogastritis of poultry as well as preparation method and application of traditional Chinese medicine composition and medicine composition

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Application publication date: 20180306