CN104304271B - A kind of binary pesticide composition and purposes - Google Patents

A kind of binary pesticide composition and purposes Download PDF

Info

Publication number
CN104304271B
CN104304271B CN201410280575.3A CN201410280575A CN104304271B CN 104304271 B CN104304271 B CN 104304271B CN 201410280575 A CN201410280575 A CN 201410280575A CN 104304271 B CN104304271 B CN 104304271B
Authority
CN
China
Prior art keywords
parts
active component
compound
compositions
pesticide composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201410280575.3A
Other languages
Chinese (zh)
Other versions
CN104304271A (en
Inventor
宋玉泉
张国生
李轲轲
冯聪
高亮
杨辉斌
李斌
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenyang Sciencreat Chemicals Co Ltd
Original Assignee
Shenyang Sciencreat Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenyang Sciencreat Chemicals Co Ltd filed Critical Shenyang Sciencreat Chemicals Co Ltd
Priority to CN201410280575.3A priority Critical patent/CN104304271B/en
Priority claimed from CN201110410182.6A external-priority patent/CN103155929B/en
Publication of CN104304271A publication Critical patent/CN104304271A/en
Application granted granted Critical
Publication of CN104304271B publication Critical patent/CN104304271B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

The invention discloses a kind of binary pesticide composition, active component one is selected from compound A, and active component two is selected from macrolide insecticide;Described macrolide insecticide includes avilamycin, emamectin-benzoate, pleocidin, ethyl pleocidin, emaricin or milbemectin etc.;Described compound A has a following structure:

Description

A kind of binary pesticide composition and purposes
The application is the divisional application of Chinese invention patent application, the applying date of original application: on December 9th, 2011, application Number: 201110410182.6, invention and created name: a kind of binary pesticide composition and application thereof, publication number: CN 103155929A;Owing to original application exists the unicity problem that auditor points out, applicant proposes this divisional application.
Technical field
The invention belongs to field of pesticides, relate to a kind of binary pesticide composition and purposes.
Background technology
Insecticide has significantly effect in terms of preventing and treating agriculture and forestry injurious insect or urban health insect.
Chinese invention patent CN101333213A discloses a kind of 1-substituted pyridyl-pyrazol acid amide compounds and control thereof Insect pest and the purposes of disease, wherein compound 1.25 (hereinafter referred to as compound A) can be used for preventing and treating various pests, especially Lepidoptera pest is had prominent prevention effect.
Containing the insecticide of single-activity component, Pest control uses continuously, easily make insect develop immunity to drugs.Pass through The insecticide of two kinds of active components is compounded into blending ingredients by a certain percentage, often can improve preventive effect, reduces effective ingredient Consumption, cost-effective, the generation of pest resistance to insecticide can be delayed simultaneously.
Although prior art disclosing compound A or its homologue general and can producing with other Mixture Use of Insecticides additional excellent Point and effect, but the technical scheme of the binary pesticide composition containing compound A has no concrete open.
Summary of the invention
Present invention aim at developing a kind of binary pesticide composition containing compound A, to meet agricultural and urban health The demand that insecticide effect is day by day improved by field pest control aspect and kind is constantly updated.
Technical scheme is as follows:
A kind of binary pesticide composition, active component one is selected from compound A, and active component two is selected from Macrolide parasite killing Agent;
Described compound A has a following structure:
Described macrolide insecticide includes avilamycin (Abamectin), emamectin-benzoate (Emamectin benzoate is called for short emamectin benzoate), pleocidin (spinosad), ethyl pleocidin (spinetoram), Emaricin (emamectin) or milbemectin (milbemectin) etc..
The preferred avilamycin of active component two, emamectin benzoate or pleocidin in the binary pesticide composition of the present invention.
In the binary pesticide composition of the present invention, the ratio of weight and number of two kinds of active components is 1:99-99:1, is preferably 1:20-20:1。
Indoor biological determination of activity demonstrates that the binary pesticide composition of the present invention has potentiation.Such as, compound A In the range of 1:20-20:1, multiple target is shown good potentiation with avilamycin;Compound A and emamectin benzoate exist In the range of 5:1-1:2, compound A and pleocidin in the range of 5:1-1:1, all demonstrate potentiation.
The compositions of the present invention can provide in finished product preparation form.Therefore, present invention additionally comprises the parasite killing of a kind of dosage form Agent compositions.With binary pesticide composition as active component, make as required cream, suspending agent, water-dispersible granules, Aqueous emulsion, soluble liquid, wettable powder, oil-suspending agent etc..In compositions, the cumulative amount of active component exists Between 0.5%-95%, preferably cumulative amount is between 1%-85%.In the compositions of the present invention, the content of active component depends on list Amount of application when solely using, also depends on mixed ratio and potentiation degree.The optimum range of active component content is according to combination The preparation type of thing and different.
The preparation of the compositions finished product preparation of the present invention can be prepared by common processing method, will active substance and liquid-carrier After the mixing of (solvent) or solid carrier, add one or more surfactants such as emulsifying agent, dispersant, wetting agent, glue Mixture, stabilizer and defoamer etc..Generally containing at least one carrier and at least one surfactant in compositions.Respectively In the case of Zhong, it should be ensured that present composition active component is uniformly distributed.
Cream usually contains the active component of 10~50%, 2~20% emulsifying agent, 0~other additives such as stabilizer of 20%, Penetrating agent, corrosion inhibitor etc., and solvent (if desired possibly together with cosolvent).
Suspending agent generally needs sand milling, to obtain stable non-deposited flowable product.Suspending agent usually contains 5~75% live Property component, 5~15% dispersant, 0.1~10% thixotropic agent, 4~10% antifreezing agent, 0~other additives such as defoamer of 10%, Preservative, stabilizer, penetrating agent and thickening agent, and liquid-carrier surplus.
Water-dispersible granules is usually made 10~100 international standard sieve meshes (1.676~0.152mm) granule, can be by squeezing Prepared by pressure, dipping or Spray granulation method.Generally water-dispersible granules contains 0.5~the active component of 75% and 5~the table of 20% Face agents such as stabilizer, wetting dispersing agent, disintegrating agent and binding agent, and inert carrier surplus.
Wettable powder usually contains the active component of 10~85%, in addition to solid inert carrier, usually contains 3~10% Dispersant, it is also possible to containing 0~the stabilizer of 10% and (or) other additives, such as penetrating agent or sticker.
Aqueous emulsion is that former medicine, organic solvent, surfactant mixing are formed oil phase;Water, antifreezing agent are mixed, Become transparent and homogeneous aqueous phase.With high-shear emulsion machine high speed shear oil phase, slowly aqueous phase is added oil phase simultaneously, the most effectively become Point 1~60%, surfactant 5~20%, antifreezing agent 2~10%, water surplus.
Microemulsion is former medicine, organic solvent, surfactant, water to be mixed, and becomes transparent and homogeneous aqueous phase.Generally have Effect composition 1~50%, surfactant 10~40%, antifreezing agent 2~10%, water surplus.
Soluble liquid is active component, organic solvent, surfactant to be mixed, and becomes transparent and homogeneous liquid.Logical Often effective ingredient 1~50%, surfactant 6~20%, organic solvent surplus.
Oil-suspending agent is that active component, surfactant, oil based vehicle are added sand milling in sand mill, until particle diameter is qualified, Generally effective ingredient 2~60%, surfactant 6~20%, oil based vehicle surplus.
Aqueous dispersion liquid and the emulsion (combination obtained such as cream, wettable powder or the concentrate of the dilute with water present invention Thing) also within the scope of the invention.Above-mentioned emulsion can be water-in-oil type or oil-in-water type, can have thick slurry Shape denseness.
The preparation of the compositions finished product preparation of the present invention can use (liquid or solid) well known to those skilled in the art to carry Body and various auxiliary agent.Such as include but not limited to following all kinds of material.
Suitable liquid-carrier or solvent can be water, various aromatic hydrocarbons, aliphatic hydrocarbon, ketone, ethers etc., such as toluene, diformazan Benzene, acetone, cyclohexanone, dimethylbenzene, benzene, hexamethylene, isopropanol, ethylene glycol, sorbitol, methanol, ethanol, butanol, One or more in dimethylformamide, naphthalane, machine oil, petroleum ether etc..
Suitable solid carrier includes clay that is natural or that synthesize and silicate, it is adaptable to the solid carrier of powder includes natural Formed rock dust, Chalk, quartz, clay, montmorillonite, silicon dioxide, kieselguhr, Pumex, Gypsum Fibrosum, Talcum, The mineral (such as microdispersed silicic acid or aluminium oxide) ground of bentonite, Kaolin, potter's clay and synthesis.The granule being suitable for carries Body includes that crush and classification natural rock such as calcite, marble, Pumex, meerschaum and dolomite and by Organic substance The synthesis granule made with the powder of inorganic matter.
Suitable co-solvents is methanol, phenol, isoamyl alcohol, dimethyl sulfoxide, ethyl acetate, butanone, dimethylformamide etc. In one or more.
Suitable emulsifying agent can be ethoxylated castor oil, polyoxyethylene (n20) phenethyl phenol ether through reaction oleate, alkylaryl gather Oxygen ethylene polyethenoxy ether, alkylaryl formaldehyde resin polyoxyethylene ether, agriculture breast 0201B, agriculture breast 0203B, agriculture breast T-20, Agriculture breast S-80, agriculture breast 507#, agriculture breast 100#, agriculture breast 36#, agriculture breast 600#, agriculture breast 1601#, agriculture breast 2201# etc..
Suitable dispersant can be sodium lignin sulfonate, calcium lignosulfonate, condensation compound of methyl naphthalene sulfonic acid and formaldehyde, methyl naphthalene Sodium sulfonate formaldehyde condensation products, methanonaphthalene sodium sulfonate, oleic acid methylaminoethyl sodium sulfonate, epoxidized polyether, to tertbutyl ether, Piperonyl butoxide, alkyl amide taurate, dibutyl naphthalenesulfonic acid formaldehyde condensation products, alkylphenol-polyethenoxy based phosphates, Methylcellulose etc..
Suitable wetting agent can be sodium sulfate, sodium laurylsulfate, methanonaphthalene sodium sulfonate, dodecylbenzene sodium sulfonate, Calcium dodecyl benzene sulfonate, Negel aliphatic alcohol polyethenoxy base ether, alkylphenol-polyethenoxy base ether etc..
Suitable thickening agent can be synthesis (such as carbonyl methylol, polyvinyl alcohol, polyvinyl acetate) or natural water-soluble Property polymer is (such as xanthan gum, gelatin, Radix Acaciae senegalis, polyvinylpyrrolidone, aluminium-magnesium silicate, polyvinyl alcohol, poly-second Glycol, phenolic resin, Lac, carboxymethyl cellulose and sodium alginate etc.), add preparation with powder, granule or latex form In.
Suitable defoamer is bubble enemy, silicone, C8~10 fatty alcohol, phosphoric acid ester, C10~20 saturated fat acids (as Capric acid) and amide etc..
Suitable oxidant is: potassium chlorate, sodium chlorate, potassium perchlorate, sodium nitrate, potassium nitrate, potassium permanganate etc..
Suitable binding agent can be polyvinyl alcohol, polyvinyl acetate, xanthan gum, gelatin, carboxymethyl cellulose and Sargassum Acid sodium etc..Additionally, defoamer can be silicone etc..
Aerosol can be made during for preventing and treating city insect, need to add wherein propellant, it is also possible to make bait formulation combination Thing, in addition to containing active component, is suitable to the foodstuff of insect's food-taking, optional attractant possibly together with one or more and appoints The wetting agent of choosing.
The compositions of the present invention is suitable for preventing and treating multiple important agriculture and forestry injurious insect or urban health insect, as mythimna separata, beet armyworm, Bollworm, cutworm, lopper worm, apple skin worm, rice leaf roller, Pyrausta nubilalis (Hubern)., striped rice borer, diamondback moth, dark greyish green Worm, fall webworms, tent caterpillar, gypsymoth, Locusta migratoria manilensis (Meyen), subterranean pest-insect, leaf miner, liriomyza bryoniae, aphid, demodicid mite class Deng, city insect such as Coptotermes formosanus Shtrari., cockroach, Formica fusca, flies, mosquito class etc..For fruit tree such as Fructus Mali pumilae, pears, mandarin orange, Fructus Litchi etc., Cereal such as Semen Tritici aestivi, Oryza sativa L. etc., beans such as Semen sojae atricolor, Kidney bean etc., Cotton Gossypii, vegetable such as Caulis et Folium Brassicae capitatae, Brassica oleracea L. var. botrytis L., Chinese cabbage, Brassica campestris L, Fructus Lycopersici esculenti, Fructus Capsici etc., and flowers.During for preventing and treating city insect, may be used for family, various public place, office field Institute, and there are the trees of termite damage, dykes and dams etc..Therefore, present invention additionally comprises the present composition and control agriculture and forestry injurious insect Or the purposes of urban health insect.
Present invention additionally comprises a kind of method controlling insect pest, the present composition can be imposed on the evil needing to control with effective dose On the medium of worm or its growth.The more suitable effective dose being generally selected is per hectare 10 grams to 500 grams, preferably effectively agent Amount is per hectare 15 grams to 100 grams.
Present invention have the advantage that
One is that the compositions of the present invention shows obvious potentiation in certain ratio range, improves this compound to evil The prevention effect of worm.
Two is the using dosage that said composition reduces compound in the application, thus reduces use cost, reduces environmental pollution.
Three is the mechanism of action difference of each effective ingredient in said composition, and the problem that there is not cross resistance uses its pest control The generation of pest resistance to insecticide can be delayed, and improve the prevention effect of antagonism population.
Detailed description of the invention
Specific examples below is used for further describing the present invention, but the present invention is only limitted to absolutely not these examples.Embodiment In each component percentages or proportioning be by weight.Active component in each formula calculates with effective content.
Formulation Example
The preparation of embodiment 1,6% avermectin compounds A cream
By recipe requirements, it is separately added into 1.5 parts of avilamycin, 4.5 parts of compound A, 7 parts of agriculture breast 0201B, 3 parts of agriculture breasts NP-15,2 parts of Nongru-700s, 12 parts of dimethylformamides, dimethylbenzene complement to 100%, and mix homogeneously, if desired by heat Heating in water bath dissolves, and i.e. obtains 6% avermectin compounds A cream.
The preparation of embodiment 2,20% avermectin compounds A wettable powder
By recipe requirements, by 5 parts of avilamycin, 15 parts of compound A, 2 parts of sodium lauryl sulphates, 6 parts of naphtholsulfonic acids Formaldehyde condensation products sodium salt, 4 parts of sodium lignin sulfonates, 5 parts of White Carbon blacks, bentonite etc. complement to 100%, are sufficiently mixed, warp After ultra-fine pulverizer disintegrating, i.e. obtain 20% avermectin compounds A wettable powder.
The preparation of embodiment 3,20% emamectin benzoate compound A wettable powder
By recipe requirements, by 10 parts of emamectin benzoate, 10 parts of compound A, 2 parts of sodium lauryl sulphates, 6 parts of cresol sulfonic acid first Aldehyde condensate sodium salt, 4 parts of sodium lignin sulfonates, 3 parts to tertbutyl ether, 2 parts of detergent LS, 5 parts of White Carbon blacks, lightweight carbon Acid calcium is supplied surplus etc. and is sufficiently mixed, and after ultra-fine pulverizer disintegrating, i.e. obtains 20% emamectin benzoate compound A wettable powder Agent.
The preparation of embodiment 4,8% avermectin compounds A aqueous emulsion
By recipe requirements, by 2 parts of avilamycin, 6 parts of compound A, 8 parts of alkylaryl polyoxyethylene poly-oxygen propylene aethers, 15 Part 2201,15 parts of dimethylformamides of agriculture breast, 0.5 part of tetradecanol are added together, and make to be dissolved into homogeneous oil phase, at a high speed Under stirring, excess water is joined oil phase, complement to 100%, form 8% aqueous emulsion of favorable dispersibility.
The preparation of embodiment 5,6% emamectin benzoate compound A aqueous emulsion
By recipe requirements, by 2 parts of emamectin benzoate, 4 parts of compound A, 8 parts of polyoxyethylene (n20) phenethyl phenol ether through reaction oleates, 3 parts of calcium dodecyl benzene sulfonates, 2 parts of agriculture breast 507#, 5 parts of Ketohexamethylene, 3 parts of dimethylbenzene, 1 part of ten sorbitol are added together, Make to be dissolved into homogeneous oil phase, under high velocity agitation, the water of surplus is joined oil phase, form 6% first dimension of favorable dispersibility Salt compound A aqueous emulsion.
Embodiment 6,60% pleocidin compound A water-dispersible granules
By recipe requirements, by 30 parts of pleocidin, 30 parts of compound A, 6 parts of methanonaphthalene sodium sulfonates, 5 parts of naphtholsulfonic acids Formaldehyde condensation products, 5 parts of epoxidized polyethers, 5 parts of soluble starches, 5 parts of sodium sulfate, 5 parts of Gypsum Fibrosum bentonite, bentonite are supplied Surpluses etc. carry out co-grinding, after adding water kneading, are equipped with in the comminutor of certain specification screen cloth carrying out pelletize.Then Drying, screening (by screen cloth scope) i.e. obtain 60% pleocidin compound A water-dispersible granules again.
Embodiment 7,50% avermectin compounds A water-dispersible granules
By recipe requirements, by 12.5 parts of avilamycin, 37.5 parts of compound A, 15 parts of methyl naphthalene sulfonate formaldehyde condensates, 5 parts of sodium alginates, 5 parts of PEG 8000s, 15 parts of sodium sulfate, bentonite etc. complement to 100%, carry out co-grinding, After adding water kneading, it is equipped with in the comminutor of certain specification screen cloth carrying out pelletize.Drying, screening are (by screen cloth the most again Scope) i.e. obtain 50% avermectin compounds A water-dispersible granules.
Embodiment 8,10% avermectin compounds A suspending agent
By recipe requirements, by 5 parts of avilamycin, 5 parts of compound A, 1601,6 parts of agriculture breast 0201B of 3 parts of agriculture breasts, 0.3 Part xanthan gum, 0.5 part of white carbon, 5 parts of ethylene glycol, complement to 100% with water, add in sand milling still, carry out finely ground, system Become 10% avermectin compounds A suspending agent.
Embodiment 9,12% pleocidin compound A suspending agent
By recipe requirements, by 4 parts of pleocidin, 8 parts of compound A, 3 parts of sodium lignin sulfonates, 5 parts of naphthalene sulfonate formaldehyde Condensation substance, 1601,3 parts of agriculture breast 0201B of 2 parts of agriculture breasts, 0.1 part of xanthan gum, 0.2 part of white carbon, 5 parts of ethylene glycol, water are mended Foot surplus etc. adds in sand milling still, carries out finely ground, makes 12% pleocidin compound A suspending agent.
Embodiment 10,10% emamectin benzoate compound A suspending agent
By recipe requirements, by 5 parts of emamectin benzoate, 5 parts of compound A, 1 part of agriculture breast S-80,2 parts of Nongru-700 #, 5 parts of agricultures Breast 0203B, 4 parts of sodium lignin sulfonates, 3 parts of nekal formaldehyde condensation products, 0.5 part of xanthan gum, 0.8 part of Linesless charcoal Black, 5 parts of ethylene glycol, water are supplied surplus etc. and are added in sand milling still, carry out finely ground, make 10% emamectin benzoate compound A and hang Floating agent.
Embodiment 11,10% pleocidin compound A suspending agent
By recipe requirements, by 5 parts of pleocidin, 5 parts of compound A, 3 parts of naphthalenesulfonic acid-formaldehyde condensates, 5 parts of methyl naphthalenes Sodium sulfonate formaldehyde condensation products, 3 parts of agriculture breast NP-7,3 parts of agriculture breast 0201B, 3 parts of triethyl phosphates, 5 parts of ethylene glycol, water are mended Foot surplus etc. adds in sand milling still, carries out finely ground, makes 10% pleocidin compound A suspending agent.
Embodiment 12,10% avermectin compounds A microemulsion
By recipe requirements, by 5 parts of avilamycin, 5 parts of compound A, 10 parts of diphenyl phenolic group polyoxyethylene (n18) ether formaldehyde Condensation substance, 2201,5 parts of Nongru-700s of 10 parts of agriculture breasts#, 10 parts of ethyl acetate, 15 parts of Ketohexamethylene, be added together, make molten Solution uniformly oil phase, surplus water complements to 100%, under high velocity agitation, aqueous phase joins oil phase or is added by oil phase To aqueous phase, form 10% avermectin compounds A microemulsion of favorable dispersibility.
Embodiment 13,15% avermectin compounds A soluble concentrate
By recipe requirements, by 5 parts of avilamycin, 10 parts of compound A, 15 parts of agriculture breasts 507#, 5 parts of agriculture breasts 1601,6 parts Agriculture breast 100#, 12 parts of dimethylformamide, 10 parts of methanol, 20 parts of dimethyl sulfoxide, 17 parts of methyl molten fiber mix homogeneously, Use hot bath heating for dissolving if desired, 15% avermectin compounds A soluble concentrate can be prepared.
Embodiment 14,30% avermectin compounds A oil-suspending agent
By recipe requirements, by 15 parts of avilamycin, 15 parts of compound A, 6 parts of agriculture breast 0201B, 2 parts of Nongru-700s, 5 Part agriculture breast S-80,10 parts of methyl oleates, 3 parts of white carbons, 1 part of agriculture breast T-20, surplus methylated soya oil complement to 100%, Add in sand milling still, carry out finely ground, make 30% avermectin compounds A oil-suspending agent.
Indoor biological determination of activity
The embodiment 15 compositions containing the compound A synergism determination to diamondback moth
For examination object: diamondback moth (Plutella xylostella), 2 instar larvaes, the sensitive strain of indoor feeding.
Test condition: temperature: 24~26 DEG C, humidity: RH60%, illumination: L:D=14:10
Test method: use infusion process to process, fetched by the cabbage leaves of greenhouse production, make diameter 2cm leaf dish, will Leaf dish impregnates 5s in medicinal liquid, dries in the shade after taking-up, puts in the 9cm culture dish being lined with filter paper, selects the examination worm of neat and consistent Access in culture dish, often process and be repeated 4 times.Examination worm after processing is placed in observation ward, routine observation examination worm response situation, 48h " Invest, Then Investigate " is dead, borer population of living, and calculates mortality rate.
Evaluating and use Bliss method, the method is one of classical way evaluating mixture effect.The independence that Bliss proposes according to it Synergy concept is thought, theoretical mortality rate P during Mixture Use of Insecticides can calculate with following formula:
P=Pm+Pn(1-Pm)
PmIt it is the mortality rate (%) of the first active component target when concentration is m;PnIt is that the second active component concentration is The mortality rate (%) of target during n.
If two kinds of active component actuals of target after mixing with finite concentration more than theoretical mortality rate P, then judge Two kinds of active components are used in mixed way under setting concentration has potentiation, otherwise is then antagonism.
The results are shown in Table 1.
The table 1 compositions containing compound A is to diamondback moth 2 instar larvae synergism determination
Embodiment 16 compound A and avilamycin are used in mixed way diamondback moth toxicity determination test
For examination object: diamondback moth (Plutella xylostella), 3 instar larvaes, the sensitive strain of indoor feeding.
Test condition: temperature: 24~26 DEG C, humidity: RH60%, illumination: L:D=14:10
Test medication liquid making method: the most accurately weigh reagent agent with electronic analytical balance, respectively two kinds of former medicines are added After appropriate solvent is completely dissolved, it is configured to desired concn mother solution with the water containing 0.1% Tween 80, by two kinds of effective ingredient mother solutions It is hybridly prepared into mixed solution by a certain percentage, is diluted to the serial medicinal liquid having finite concentration gradient by EXPERIMENTAL DESIGN dosage respectively.
Test method: use infusion process to process, fetched by the cabbage leaves of greenhouse production, make diameter 2cm leaf dish, will Leaf dish impregnates 5s in medicinal liquid, dries in the shade after taking-up, puts in the 9cm culture dish being lined with filter paper, selects the examination worm of neat and consistent Access in culture dish, often process and be repeated 4 times.Examination worm after processing is placed in observation ward, routine observation examination worm response situation, 48h " Invest, Then Investigate " is dead, borer population of living.
Calculating corrected mortality with abbott formula, appliance computer program is obtained each mixed for examination single dose and variant proportioning Virulence regression equation formula, LC50 value and 95% confidence limit, by Sun Yunpei (Sun Y-P) method, obtain the common poison that each proportioning is mixed Coefficient, is evaluated.If co-toxicity coefficient is summation action close to 100, hence it is evident that higher than 100 for potentiation, hence it is evident that be less than 100 is antagonism.
Result of the test is shown in Table 2.As can be seen from the table, compound A is mixed to diamondback moth for trying each proportioning with avilamycin All show potentiation.
Table 2: compound A Abamectin on Plutella indoor joint toxicity measuring result
Embodiment 17 compound A and avilamycin are used in mixed way striped rice borer toxicity determination test
For examination object: striped rice borer (Chilo suppressalis), 2 instar larvaes, the sensitive strain of indoor feeding.
Test condition: temperature: 25~27 DEG C, humidity: RH60%, illumination: L:D=14:10
Drug solution preparation method is with embodiment 16.
Test method: use man-made feeds culture plate method, 24 well culture plates that selection standard is clean, every hole adds 1ml people Work feedstuff, after cooled and solidified, adds 0.05ml medicinal liquid with continuous sampler to each hole of culture plate, then puts at cool place oneself So dry in the shade.The examination worm selecting neat and consistent is accessed in culture plate, and 1, every hole often processes and is repeated 4 times.Examination after processing Worm is placed in observation ward, routine observation examination worm response situation, and 72h " Invest, Then Investigate " is dead, borer population of living.Calculation Estimation method is with implementing Example 16.
Result of the test is shown in Table 3.As can be seen from the table, compound A is mixed to striped rice borer for trying each proportioning with avilamycin All show potentiation.
Table 3: compound A avilamycin is to striped rice borer indoor joint toxicity measuring result
Embodiment 18 compound A and avilamycin are used in mixed way Pyrausta nubilalis (Hubern). toxicity determination test
For examination object: Pyrausta nubilalis (Hubern). (Ostrinia furnacalis), 3 instar larvaes, the sensitive strain of indoor feeding.
Test condition: temperature: 23~25 DEG C, humidity: RH60%, illumination: L:D=14:10
Drug solution preparation method is with embodiment 16, and test method is with embodiment 17, and Calculation Estimation method is with embodiment 16.
Result of the test is shown in Table 4.As can be seen from the table, compound A is mixed to Pyrausta nubilalis (Hubern). for trying each proportioning with avilamycin All show potentiation.
Table 4: compound A avilamycin is to Pyrausta nubilalis (Hubern). indoor joint toxicity measuring result

Claims (6)

1. a binary pesticide composition, it is characterised in that: binary pesticide composition is by active component one and activity group Points two compositions, active component one, selected from compound A, has a following structure:
Active component two is selected from emamectin benzoate;
The ratio of weight and number of active component one and active component two is 5:1~1:2.
2. according to the compositions described in claim 1, it is characterised in that: can make as required cream, suspending agent, Water-dispersible granules, aqueous emulsion, microemulsion, soluble liquid or wettable powder.
3. according to the compositions described in claim 2, it is characterised in that: in compositions, the cumulative amount of active component exists Between 0.5%-95%.
4. according to the compositions described in claim 3, it is characterised in that: in compositions, the cumulative amount of active component exists Between 1%-85%.
5. one kind controls agriculture and forestry injurious insect or the use of urban health insect according to the binary pesticide composition described in claim 1 On the way.
6. the method controlling insect pest, it is characterised in that: the compositions described in claim 1 is imposed on effective dose Need on the medium of insect or its growth controlled.
CN201410280575.3A 2011-12-09 2011-12-09 A kind of binary pesticide composition and purposes Active CN104304271B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410280575.3A CN104304271B (en) 2011-12-09 2011-12-09 A kind of binary pesticide composition and purposes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201110410182.6A CN103155929B (en) 2011-12-09 2011-12-09 Binary pesticide composition and application thereof
CN201410280575.3A CN104304271B (en) 2011-12-09 2011-12-09 A kind of binary pesticide composition and purposes

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201110410182.6A Division CN103155929B (en) 2011-12-09 2011-12-09 Binary pesticide composition and application thereof

Publications (2)

Publication Number Publication Date
CN104304271A CN104304271A (en) 2015-01-28
CN104304271B true CN104304271B (en) 2016-08-17

Family

ID=52359709

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410280575.3A Active CN104304271B (en) 2011-12-09 2011-12-09 A kind of binary pesticide composition and purposes

Country Status (1)

Country Link
CN (1) CN104304271B (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1775027A (en) * 2005-11-21 2006-05-24 河北威远生物化工股份有限公司 Disinsection soluble granules containing methylamino avermection benzoate
CN101014247A (en) * 2004-07-01 2007-08-08 杜邦公司 Synergistic mixtures of anthranilamide invertebrate pest control agents
WO2007112847A2 (en) * 2006-03-29 2007-10-11 Bayer Cropscience Ag Active ingredient combinations with insecticidal properties
CN101333213A (en) * 2008-07-07 2008-12-31 中国中化集团公司 1-substituted pyridyl-pyrazol acid amide compounds and use thereof
CN101700025A (en) * 2009-09-17 2010-05-05 张志高 Synergistic insecticidal composition

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101014247A (en) * 2004-07-01 2007-08-08 杜邦公司 Synergistic mixtures of anthranilamide invertebrate pest control agents
CN1775027A (en) * 2005-11-21 2006-05-24 河北威远生物化工股份有限公司 Disinsection soluble granules containing methylamino avermection benzoate
WO2007112847A2 (en) * 2006-03-29 2007-10-11 Bayer Cropscience Ag Active ingredient combinations with insecticidal properties
CN101333213A (en) * 2008-07-07 2008-12-31 中国中化集团公司 1-substituted pyridyl-pyrazol acid amide compounds and use thereof
CN101700025A (en) * 2009-09-17 2010-05-05 张志高 Synergistic insecticidal composition

Also Published As

Publication number Publication date
CN104304271A (en) 2015-01-28

Similar Documents

Publication Publication Date Title
CN104413038B (en) Binary insecticide composition and application
CN104663704B (en) One kind contains the acaricidal insecticide acaricide composition of ATP synthetase inhibitors classes
CN104663692B (en) A kind of insecticide acaricide composition containing insect growth regulator, IGR insecticides
CN104026143B (en) Binary pesticide composition and uses thereof
CN104351189B (en) Binary pesticide composition and uses thereof
CN106305758A (en) Synergistic and compounded pest and mite killing composition
CN104663702A (en) Insecticidal and acaricidal composition containing esbiothrin insecticide
CN104663679A (en) Pest-killing and mite-killing composition containing macrolide insecticide
CN104663693B (en) A kind of composition of containing pyriminostrobin and its application
CN103155935B (en) Binary pesticide composition
CN104663688B (en) A kind of insecticide acaricide composition containing Bifenazate
CN104738063B (en) Binary insecticide composition and application
CN104026156B (en) A kind of binary pesticide composition and application thereof
CN104026146B (en) A kind of binary insecticides and purposes
CN105766923A (en) Insecticidal acaricidal composition
CN105724395B (en) A kind of binary pesticide composition and its application
CN104304271B (en) A kind of binary pesticide composition and purposes
CN103404531A (en) Biological compound insecticide containing toosedarin and imidacloprid and preparation method and application thereof
CN104412991B (en) Binary pesticide composition and application thereof
CN105638693A (en) Insecticidal combination containing chlorofluoro cyantraniliprole and fipronil
CN104855399A (en) Insecticidal combination containing butene-fipronil and fluorine benzene worm amide
CN104255759B (en) Containing the Pesticidal combination of matrine and metaflumizone
CN104082322B (en) A kind of containing Nylar with the insecticide acaricide composition of Bifenazate
CN106305727A (en) Synergist-containing insecticidal acaricidal composition
CN106305732A (en) Flutenzine-containing insecticidal acaricidal composition

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant