CN104302300B - 抗菌含钙材料 - Google Patents

抗菌含钙材料 Download PDF

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Publication number
CN104302300B
CN104302300B CN201380023551.3A CN201380023551A CN104302300B CN 104302300 B CN104302300 B CN 104302300B CN 201380023551 A CN201380023551 A CN 201380023551A CN 104302300 B CN104302300 B CN 104302300B
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CN
China
Prior art keywords
lithium
ttcp
bone implant
paa
calcium
Prior art date
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Application number
CN201380023551.3A
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English (en)
Chinese (zh)
Other versions
CN104302300A (zh
Inventor
陈瑾惠
朱建平
陈长庚
杨秉宸
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Joy Medical Devices Corp
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Individual
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Priority to CN201711401529.4A priority Critical patent/CN107982574B/zh
Publication of CN104302300A publication Critical patent/CN104302300A/zh
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Materials Engineering (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201380023551.3A 2012-05-07 2013-05-06 抗菌含钙材料 Active CN104302300B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711401529.4A CN107982574B (zh) 2012-05-07 2013-05-06 抗菌含钙材料

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261643500P 2012-05-07 2012-05-07
US61/643,500 2012-05-07
PCT/US2013/039661 WO2013169633A1 (en) 2012-05-07 2013-05-06 Antibacterial calcium-based materials

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201711401529.4A Division CN107982574B (zh) 2012-05-07 2013-05-06 抗菌含钙材料

Publications (2)

Publication Number Publication Date
CN104302300A CN104302300A (zh) 2015-01-21
CN104302300B true CN104302300B (zh) 2018-09-14

Family

ID=49512698

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201380023551.3A Active CN104302300B (zh) 2012-05-07 2013-05-06 抗菌含钙材料
CN201711401529.4A Active CN107982574B (zh) 2012-05-07 2013-05-06 抗菌含钙材料

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201711401529.4A Active CN107982574B (zh) 2012-05-07 2013-05-06 抗菌含钙材料

Country Status (7)

Country Link
US (2) US10207023B2 (enExample)
EP (1) EP2846811B1 (enExample)
JP (1) JP6174684B2 (enExample)
KR (3) KR20200050477A (enExample)
CN (2) CN104302300B (enExample)
TW (1) TWI630003B (enExample)
WO (1) WO2013169633A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI651103B (zh) 2013-12-13 2019-02-21 萊特醫技股份有限公司 多相骨移植替代材料
CN110558311A (zh) * 2019-09-17 2019-12-13 海南医学院第一附属医院 一种创战伤中保存离体骨的医用材料及其制备方法
KR102284280B1 (ko) * 2019-12-13 2021-08-02 가톨릭대학교 산학협력단 착색방지기능을 가지는 코팅 조성물 및 이를 이용한 임시 치관
CN117339026B (zh) * 2023-11-09 2024-05-14 广州医科大学附属口腔医院（广州医科大学羊城医院） 用于植入人体牙槽骨中的可吸收支架的制备及应用

Citations (7)

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US20030220414A1 (en) * 2002-04-04 2003-11-27 Niklas Axen Biocompatible cement compositions and method for filling a skeletal cavity using said cement compositions
WO2009105614A2 (en) * 2008-02-22 2009-08-27 Dermal Technologies, Llc Compositions for tissue augmentation
CN101686861A (zh) * 2007-07-09 2010-03-31 艾斯特勒科技公司 包含锂离子的骨组织植入物
WO2011040851A1 (en) * 2009-10-02 2011-04-07 Doxa Ab Calcium aluminate based paste for stabilizing dental implants and restoring tissue attachment after surgery and methods therefor
US20110150963A1 (en) * 2009-12-21 2011-06-23 Clineff Theodore D Bioactive antibacterial bone graft materials
US20110182995A1 (en) * 2007-02-22 2011-07-28 Saeed Asgary Medical and dental biomaterial and method of use for the same
WO2012030664A1 (en) * 2010-08-30 2012-03-08 Pulmatrix, Inc. Dry powder formulations and methods for treating pulmonary diseases

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US5705273A (en) * 1995-03-08 1998-01-06 The Ohio State University Method for strengthening dental restorative materials
US6071528A (en) * 1997-02-19 2000-06-06 Ultradent Products, Inc. Adhesive antimicrobial and/or reparative dentin stimulating dental compositions and methods for forming and using such compositions
JP2000313817A (ja) * 1999-04-30 2000-11-14 Ishizuka Glass Co Ltd 樹脂添加剤
CN1475279B (zh) * 2002-08-13 2010-04-14 中国科学院福建物质结构研究所 一种羟基磷灰石骨水泥人工骨的制备方法
US6930144B2 (en) * 2003-06-24 2005-08-16 Hewlett-Packard Development Company, L.P. Cement system including a binder for use in freeform fabrication
DE102004026432A1 (de) * 2004-05-29 2005-12-22 Schott Ag Glaszusammensetzungen als antimikrobieller Zusatz für Dentalmaterialien und deren Verwendung
JP4764685B2 (ja) * 2005-09-20 2011-09-07 旭ファイバーグラス株式会社 抗菌剤、それを含む樹脂組成物及び成形材料
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030220414A1 (en) * 2002-04-04 2003-11-27 Niklas Axen Biocompatible cement compositions and method for filling a skeletal cavity using said cement compositions
US20110182995A1 (en) * 2007-02-22 2011-07-28 Saeed Asgary Medical and dental biomaterial and method of use for the same
CN101686861A (zh) * 2007-07-09 2010-03-31 艾斯特勒科技公司 包含锂离子的骨组织植入物
WO2009105614A2 (en) * 2008-02-22 2009-08-27 Dermal Technologies, Llc Compositions for tissue augmentation
WO2011040851A1 (en) * 2009-10-02 2011-04-07 Doxa Ab Calcium aluminate based paste for stabilizing dental implants and restoring tissue attachment after surgery and methods therefor
US20110150963A1 (en) * 2009-12-21 2011-06-23 Clineff Theodore D Bioactive antibacterial bone graft materials
WO2012030664A1 (en) * 2010-08-30 2012-03-08 Pulmatrix, Inc. Dry powder formulations and methods for treating pulmonary diseases

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Preparation of calcium aluminate cement for hard tissue repair: Effects of lithium fluoride and maleic acid on setting behavior, compressive strength, and biocompatibility;Seung-Han Oh et al.;《JOURNAL OF BIOMEDICAL MATERIALS RESEARCH》;20021215;第62卷(第4期);第593-599页 *

Also Published As

Publication number Publication date
WO2013169633A1 (en) 2013-11-14
KR20200065099A (ko) 2020-06-08
TW201345570A (zh) 2013-11-16
US10207023B2 (en) 2019-02-19
KR102214257B1 (ko) 2021-02-09
KR20200050477A (ko) 2020-05-11
JP2015520148A (ja) 2015-07-16
EP2846811A1 (en) 2015-03-18
CN107982574B (zh) 2021-01-01
US20130295193A1 (en) 2013-11-07
US20190117826A1 (en) 2019-04-25
EP2846811B1 (en) 2018-03-14
CN107982574A (zh) 2018-05-04
TWI630003B (zh) 2018-07-21
CN104302300A (zh) 2015-01-21
KR20150004826A (ko) 2015-01-13
EP2846811A4 (en) 2015-05-06
JP6174684B2 (ja) 2017-08-02

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Patentee before: Yang Bingchen