CN104284680A - 使用对受体的亲和力增加的突变型light分子用于癌症治疗的方法和组合物 - Google Patents

使用对受体的亲和力增加的突变型light分子用于癌症治疗的方法和组合物 Download PDF

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CN104284680A
CN104284680A CN201280069840.2A CN201280069840A CN104284680A CN 104284680 A CN104284680 A CN 104284680A CN 201280069840 A CN201280069840 A CN 201280069840A CN 104284680 A CN104284680 A CN 104284680A
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light
tumor
antibody
cells
compositions
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Y·X·傅
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University of Chicago
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University of Chicago
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CN201280069840.2A 2011-12-15 2012-12-11 使用对受体的亲和力增加的突变型light分子用于癌症治疗的方法和组合物 Pending CN104284680A (zh)

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US201161576222P 2011-12-15 2011-12-15
US61/576,222 2011-12-15
PCT/US2012/069013 WO2013090293A1 (en) 2011-12-15 2012-12-11 Methods and compositions for cancer therapy using mutant light molecules with increased affinity to receptors

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US (2) US9493532B2 (enExample)
EP (1) EP2790730B1 (enExample)
JP (2) JP2015501839A (enExample)
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AU (1) AU2012352454A1 (enExample)
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Cited By (6)

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CN106701825A (zh) * 2016-11-17 2017-05-24 中国科学院生物物理研究所 腺病毒疫苗Ad‑LIGHT‑HBsAg及其用于治疗慢性乙肝的用途
CN108348590A (zh) * 2015-09-18 2018-07-31 综合医院公司以麻省总医院名义经营 用于治疗癌症的具有抗趋除特性的组合物
CN109125105A (zh) * 2017-06-27 2019-01-04 株式会社爱茉莉太平洋 包含tnfsf14蛋白的皮肤美白用组合物
CN116083435A (zh) * 2022-11-04 2023-05-09 吉林大学 以人源light截短型突变蛋白为基础的抗肿瘤的应用
CN116426483A (zh) * 2021-12-30 2023-07-14 南京紫珑生物科技有限公司 Cd258蛋白在免疫治疗中的应用
WO2023237051A1 (en) * 2022-06-08 2023-12-14 Analytical Biosciences Shanghai Limited Light muteins and uses thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012352454A1 (en) 2011-12-15 2014-07-17 The University Of Chicago Methods and compositions for cancer therapy using mutant light molecules with increased affinity to receptors
WO2014157692A1 (ja) 2013-03-29 2014-10-02 大日本住友製薬株式会社 Ｗｔ１抗原ペプチドコンジュゲートワクチン
US11000603B2 (en) 2015-04-14 2021-05-11 Benhealth Biopharmaceutic (Shenzhen) Co., Ltd. Multi-specific binding conjugate, related pharmaceutical compositions and use
ES2993462T3 (en) * 2015-05-20 2024-12-30 Sumitomo Pharma Co Ltd Combination of wt1 antigen peptide, immunomodulator and wt1 helper peptide
EP3450460B1 (en) * 2016-04-29 2023-07-12 Benhealth Biopharmaceutic (Shenzhen) Co. Ltd. Multi-specific binding conjugate, related pharmaceutical compositions and use
CN109689692B (zh) 2016-06-22 2021-11-12 本康生物制药（深圳）有限公司 用于肿瘤治疗的双特异性抗体和抗体偶联物及其应用
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