CN104257834A - Traditional Chinese medicine composition for treating cough - Google Patents
Traditional Chinese medicine composition for treating cough Download PDFInfo
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- CN104257834A CN104257834A CN201410548463.1A CN201410548463A CN104257834A CN 104257834 A CN104257834 A CN 104257834A CN 201410548463 A CN201410548463 A CN 201410548463A CN 104257834 A CN104257834 A CN 104257834A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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Abstract
The invention discloses a traditional Chinese medicine composition for treating a cough. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5-40 parts of cutworm, 3-30 parts of salvia prionitis, 5-30 parts of plantain, 3-40 parts of herba epimedii, 5-35 parts of salvia plebeia, 5-30 parts of caesalpinia cucullata and 5-40 parts of mucuna macrocarpa wallich. The traditional Chinese medicine composition is easy to prepare, remarkable in treatment effect, small in side effect and good in safety, has a cough treatment effect, and especially has a remarkable treatment effect on dry cough.
Description
Technical field
The invention belongs to technical field of pharmaceuticals, particularly a kind of Chinese medicine composition for the treatment of cough.
Background technology
Cough is a kind of protectiveness respiratory reflex action of human body.Effectively can remove the secretions in respiratory tract by coughre flex or enter the foreign body of air flue.But cough also has disadvantageous one side, violent cough can cause respiratory tract hemorrhage, and as a long time, frequently, violent cough affects work, has a rest, even causes laryngalgia, and hoarseness and breathing myalgia, then belong to pathological phenomenon.Usual people adopt to take chemical drugs and treat, but, not fully up to expectations with existing chemical drugs treatment cough, and take chemical drugs and easily produce side effect in various degree.
The traditional Chinese medical science of China is of long standing and well established, and of extensive knowledge and profound scholarship, Chinese medicine, with its safety, few side effects, stimulates little advantage to gastrointestinal tract not damaged with to Liver and kidney, the dark favor by extensive patients.
Therefore, Study of Traditional Chinese Medicine product is used for treating the focus that various disease always is drug development research field.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of cough, namely prevention and therapy cough is had to the Chinese medicine composition of excellent effect.Technical scheme of the present invention can overcome in prior art the present situation solving treatment cough long-term taking chemicals, reduces the security risk of patient and the generation of side effect.Technical scheme provided by the present invention is:
A kind of Chinese medicine composition for the treatment of cough, it is characterized in that, count by weight and be made up of following raw material: Stachys geobombycis C. Y. Wu 5 ~ 40 parts, Arisaema balansae Engl. grass 3 ~ 30 parts, Herba Plantaginis 5 ~ 30 parts, Herba Epimedii 3 ~ 40 parts, Herba Salviae Plebeiae 5 ~ 35 parts, Radix Zanthoxyli Spinifolii 5 ~ 30 parts and Caulis seu Radix Schisandrae Henryi 5 ~ 40 parts.
Preferably, count by weight and be made up of following raw material: Stachys geobombycis C. Y. Wu 10 ~ 20 parts, Arisaema balansae Engl. grass 3 ~ 20 parts, Herba Plantaginis 5 ~ 20 parts, Herba Epimedii 5 ~ 20 parts, Herba Salviae Plebeiae 5 ~ 25 parts, Radix Zanthoxyli Spinifolii 10 ~ 20 parts and Caulis seu Radix Schisandrae Henryi 10 ~ 20 parts.
Preferably, count by weight and be made up of following raw material: Stachys geobombycis C. Y. Wu 10 parts, Arisaema balansae Engl. grass 10 parts, Herba Plantaginis 10 parts, Herba Epimedii 10 parts, Herba Salviae Plebeiae 10 parts, Radix Zanthoxyli Spinifolii 10 parts and Caulis seu Radix Schisandrae Henryi 10 parts.
Present invention also offers a kind of medicine, comprising above-mentioned Chinese medicine composition and pharmaceutically acceptable adjuvant, the dosage form of described medicine is the regular dosage form in pharmaceutics.
Preferably, described pharmaceutics commonly uses adjuvant is one or more in starch, sucrose, dextrin, lactose micropowder, silica gel, aspartame, mannitol, sodium benzoate, sucrose and Mel.
Preferably, described dosage form is any one in decoction, powder, granule and tablet.
In addition, the invention also discloses the application of said medicine in treatment cough.
Stachys geobombycis C. Y. Wu, call native Cordyceps, white Cordyceps, tapeworm is careless, pulmonary tuberculosis is careless, Labiatae betony Stachys geobombycis C. Y. Wu Stachya geobombycis C.Y.Wu, is used as medicine with tuber.Autumn adopts, and cleans using fresh herb or cooks and dry.Kidney tonifying lung moistening, nourishing YIN and supplementing blood, clearing heat and relieving fidgetness.For pulmonary tuberculosis cough, the deficiency of the lung is panted, and spits blood, night sweat, anemia, infantile malnutrition.
Arisaema balansae Engl. grass, for Lamiaceae Salvia platymiscium Huangpu Mus tail Salvia prionitis Hance is with all herbal medicine.Xia Qiu gathers, and cleans, using fresh herb or dry.Originate in the ground such as Jiangsu, Anhui, Zhejiang, Jiangxi, Hunan, Guangdong, Guangxi." Chinese Plants will " is recorded: " Guangxi all herbal medicine, cures mainly bacillary dysentery, diarrhoea, stomachache, flu." modern study, Arisaema balansae Engl. grass also has antineoplastic effect.In addition, Primulaceae plant Arisaema balansae Engl. grass of the same name is still had.
Herba Plantaginis, annual or biennial herb.Taproot is long, tool most sides root, how many meats.Rhizome is short.Phyllopodium is raw in rosette-stape, flat sleeping, tiltedly exhibition or upright; Blade papery, ellipse, ellipticity lanceolar or ovum shape lanceolar, herb can be used as medicine, and has effect of diuresis, heat clearing away, improving eyesight.
Herba Epimedii, a kind of medicinal plants, also be generic name, about have 50 kinds, be mainly distributed in Japan, South Africa, North of Italy to Black Sea, Korea and various places, China's Mainland, be grown on height above sea level 200 meters to 1, the area of 750 meters, like dark and damp area, be generally born in the thick grass of hillside, limit, ditch, sylvan life, in shrubbery and in rock curb seam, at present not yet by artificial introducing and planting.Herba Epimedii is Chinese conventional Chinese medicine, and have very high medical value, nourishing YIN and invigorating YANG, tonifying YANG is kept fit.Bitter and puckery flavor, suitable insomniac uses.
Herba Salviae Plebeiae is annual or biennial upright draft, high 15 ~ 90cm.Multi-branched.Main root is plump, directly stretches downwards, has most fibrous root.Heat clearing away, removing toxic substances, removing heat from blood, diuresis.For laryngopharynx swelling and pain, bronchitis, oedema due to nephritis, carbuncle; External treatment mastitis, swelling and pain of hemorrhoid, hemorrhage.
Radix Zanthoxyli Spinifolii is root or the root bark of dicotyledon medicine rutaceae Zanthoxylum Dimorphophyllum Hemsl. Var Spinifolium Rhed. Et Wils.Rattan is used as medicine, and has the effect of promoting blood circulation and stopping pain.Liana, long 3-5 rice; Raw hook thorn suberification of falling on stem forms oblate cork projection; On branch and rachis, the raw hook that falls of tool pitchy stings.
Caulis seu Radix Schisandrae Henryi is Magnoliacea plant, the rattan of dicotyledon medicine plants of Lardizabalaceae Caulis Sargentodoxae.Acute and chronic appendicitis can be controlled, rheumatic arthralgia, bloody dysentery, stranguria with blood, menoxenia, infantile malnutrition, worm pain, injury from falling down.
the beneficial effect of the technical program
1, present composition processing technique is simple, and cost of material is low, is easy to large-scale promotion and use.
2, the present composition all adopts Chinese herbal medicine to make, without any side effects, and safety is good, and pathogenic bacterium not easily produce drug resistance.
Detailed description of the invention
Below in conjunction with concrete example, the present invention is further detailed explanation.The Chinese herbal medicine mentioned in embodiment is by States Pharmacopoeia specifications medicinal part
embodiment 1: the preparation of Chinese medicine decoction and clinical effectiveness
By following component part meter by weight ratio: Stachys geobombycis C. Y. Wu 3000g, Arisaema balansae Engl. grass 3000g, Herba Plantaginis 3000g, Herba Epimedii 3000g, Herba Salviae Plebeiae 3000g, Radix Zanthoxyli Spinifolii 3000g and Caulis seu Radix Schisandrae Henryi 3000g.
The preparation method of this Chinese medicine composition decoction, comprises the following steps: get above-mentioned 7 kinds of Chinese herbal medicine, add 8 times of water gagings after drying, after boiling with intense fire, then the 2.5h that simmers in water, filter and discard medicinal residues, obtain Chinese medicine decoction.
In coughing multiple season, the present embodiment gained decoction being used for clinical, amounting to statistics 200 example.Wherein 100 examples take this decoction in advance, daily 3 times, each 100ml, take 1 day, contrast 100 example is not for take any medicine, and result shows, take in 100 examples of decoction only have 3 example suffer from cough, and other 100 examples do not take in this decoction have 85 example suffer from cough.Visible, cough epidemic season, taking this decoction in advance can effectively occur by preventing cough.
embodiment 2: the preparation of Chinese powder medicine and clinical effectiveness
By following component part meter by weight ratio: Stachys geobombycis C. Y. Wu 1000g, Arisaema balansae Engl. grass 1000g, Herba Plantaginis 1000g, Herba Epimedii 1000g, Herba Salviae Plebeiae 1000g, Radix Zanthoxyli Spinifolii 1000g and Caulis seu Radix Schisandrae Henryi 1000g.
The preparation method of this Chinese medicine composition composition powders, comprises the following steps: (1) gets above-mentioned 7 kinds of Chinese herbal medicine, dries in the shade at normal temperatures; (2) add medical material amount 10 times of water gaging 4600g, beta-schardinger dextrin-50g, heating extraction 3 times, each 1.5 hours, then filter, obtain filtrate; (3) when filtrate is through being evaporated to 60 DEG C, relative density is the thick paste of 1.30 ~ 1.35, drying under reduced pressure, pulverizes, obtains fine powder; (4) by above-mentioned fine powder, mix homogeneously, obtains this Chinese powder medicine.
In clinical trial, the present embodiment gained Chinese powder medicine is used for patient treatment cough, takes 3 every day, each 20g, take 2 days, add up 50 examples altogether, wherein 45 routine patient's coughs are almost recovered.
embodiment 3: the preparation of Chinese medicine granules and clinical effectiveness
By following component part meter by weight ratio: Stachys geobombycis C. Y. Wu 9000g, Arisaema balansae Engl. grass 9000g, Herba Plantaginis 9000g, Herba Epimedii 9000g, Herba Salviae Plebeiae 9000g, Radix Zanthoxyli Spinifolii 9000g and Caulis seu Radix Schisandrae Henryi 9000g.
The preparation method of this Chinese medicinal composition granules, comprises the following steps: that (1) gets above-mentioned 7 kinds of Chinese herbal medicine, dries in the shade at normal temperatures; (2) add medical material amount 11 times of water gaging 6270g, heating extraction 2 times, each 1.5 hours, then filter, obtain filtrate; (3) when filtrate is through being evaporated to 60 DEG C, relative density is the thick paste of 1.10 ~ 1.25, drying under reduced pressure, pulverizes, obtains fine powder; (4) take mixing fine powders 1 part by weight, sucrose 4 parts, 3 parts, dextrin, mixing, granulate, 60 ~ 70 DEG C of dryings, sieve, and obtain this Chinese medicine granules.
In clinical trial, the present embodiment gained Chinese medicine granules is used for patient treatment cough, takes 3 every day, each 30g, take 3 days, add up 100 examples altogether, wherein 89 routine patient's coughs are almost recovered.
Embodiment 4: the preparation of Chinese medicinal tablet and clinical effectiveness
By following component part meter by weight ratio: Stachys geobombycis C. Y. Wu 2700g, Arisaema balansae Engl. grass 2700g, Herba Plantaginis 2700g, Herba Epimedii 2700g, Herba Salviae Plebeiae 2700g, Radix Zanthoxyli Spinifolii 2700g and Caulis seu Radix Schisandrae Henryi 2700g.
The preparation method of this Chinese medicine composition tablet, comprises the following steps: that (1) gets above-mentioned 7 kinds of Chinese herbal medicine, dries in the shade at normal temperatures; (2) add medical material amount 10 times of water gaging 5900g, heating extraction 3 times, each 2 hours, then filter, obtain filtrate; (3) when filtrate is through being evaporated to 60 DEG C, relative density is the thick paste of 1.10 ~ 1.25, drying under reduced pressure, pulverizes, obtains fine powder; (4) take mixing fine powders 1 part by weight, lactose micropowder 2 parts, sodium benzoate 1 part, mixing, tabletting, 60 ~ 70 DEG C of dryings, sieve, and obtain this Chinese medicinal tablet.
In clinical trial, the present embodiment gained Chinese medicine granules is used for patient treatment cough, takes 3 every day, each 10g, take 3 days, add up 30 examples altogether, wherein 26 routine patient's coughs are almost recovered.
The aforementioned description to concrete exemplary of the present invention is to illustrate and the object of illustration.These descriptions not want the present invention to be defined as disclosed precise forms, and obviously, according to above-mentioned instruction, can much change and change.The object selected exemplary embodiment and describe is to explain certain principles of the present invention and practical application thereof, thus those skilled in the art can be realized and utilize various different exemplary of the present invention and various different selection and change.Scope of the present invention is intended to limited by claims and equivalents thereof.
Claims (7)
1. treat the Chinese medicine composition of cough for one kind, it is characterized in that, count by weight and be made up of following raw material: Stachys geobombycis C. Y. Wu 5 ~ 40 parts, Arisaema balansae Engl. grass 3 ~ 30 parts, Herba Plantaginis 5 ~ 30 parts, Herba Epimedii 3 ~ 40 parts, Herba Salviae Plebeiae 5 ~ 35 parts, Radix Zanthoxyli Spinifolii 5 ~ 30 parts and Caulis seu Radix Schisandrae Henryi 5 ~ 40 parts.
2. Chinese medicine composition as claimed in claim 1, it is characterized in that, count by weight and be made up of following raw material: Stachys geobombycis C. Y. Wu 10 ~ 20 parts, Arisaema balansae Engl. grass 3 ~ 20 parts, Herba Plantaginis 5 ~ 20 parts, Herba Epimedii 5 ~ 20 parts, Herba Salviae Plebeiae 5 ~ 25 parts, Radix Zanthoxyli Spinifolii 10 ~ 20 parts and Caulis seu Radix Schisandrae Henryi 10 ~ 20 parts.
3. Chinese medicine composition as claimed in claim 1, is characterized in that, count by weight and be made up of following raw material: Stachys geobombycis C. Y. Wu 10 parts, Arisaema balansae Engl. grass 10 parts, Herba Plantaginis 10 parts, Herba Epimedii 10 parts, Herba Salviae Plebeiae 10 parts, Radix Zanthoxyli Spinifolii 10 parts and Caulis seu Radix Schisandrae Henryi 10 parts.
4. a medicine, is characterized in that, comprising the arbitrary described Chinese medicine composition of claim 1-3 and the acceptable adjuvant of pharmacy, the dosage form of described medicine is the regular dosage form in pharmaceutics.
5. medicine as claimed in claim 4, it is characterized in that, the acceptable adjuvant of described pharmacy is one or more in starch, sucrose, dextrin, lactose micropowder, silica gel, aspartame, mannitol, sodium benzoate, sucrose and Mel.
6. medicine as claimed in claim 4, it is characterized in that, be any one in decoction, powder, granule and tablet at described regular dosage form.
7. the application of the medicine as described in as arbitrary in claim 4 ~ 6 in treatment cough.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410548463.1A CN104257834A (en) | 2014-10-16 | 2014-10-16 | Traditional Chinese medicine composition for treating cough |
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| CN201410548463.1A CN104257834A (en) | 2014-10-16 | 2014-10-16 | Traditional Chinese medicine composition for treating cough |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105796799A (en) * | 2016-03-30 | 2016-07-27 | 覃美红 | Traditional Chinese medicine composition for treating coughs |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101301446A (en) * | 2008-06-06 | 2008-11-12 | 王丽城 | Oral Chinese medicine for treating cough due to pathogenic wind-cold |
| CN104055886A (en) * | 2014-06-24 | 2014-09-24 | 成都中医药大学 | Medicinal composition for treating chronic cough, and preparation method and application thereof |
-
2014
- 2014-10-16 CN CN201410548463.1A patent/CN104257834A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101301446A (en) * | 2008-06-06 | 2008-11-12 | 王丽城 | Oral Chinese medicine for treating cough due to pathogenic wind-cold |
| CN104055886A (en) * | 2014-06-24 | 2014-09-24 | 成都中医药大学 | Medicinal composition for treating chronic cough, and preparation method and application thereof |
Non-Patent Citations (2)
| Title |
|---|
| 盛萍: "中药治疗慢性咳嗽30例临床体会", 《青海医药杂志》 * |
| 高红勤: "邵长荣治疗咳嗽经验", 《中医杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105796799A (en) * | 2016-03-30 | 2016-07-27 | 覃美红 | Traditional Chinese medicine composition for treating coughs |
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