CN105169318A - Traditional Chinese medicinal herbal preparation for treating ichthyophthiriasis of osteoglossum bicirrhosum - Google Patents

Traditional Chinese medicinal herbal preparation for treating ichthyophthiriasis of osteoglossum bicirrhosum Download PDF

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CN105169318A
CN105169318A CN201510585788.1A CN201510585788A CN105169318A CN 105169318 A CN105169318 A CN 105169318A CN 201510585788 A CN201510585788 A CN 201510585788A CN 105169318 A CN105169318 A CN 105169318A
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parts
silver
ichthyophthiriasis
rhizoma
imperial fish
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袁国防
李洪
孙明
王亮
宋辉
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Qingdao Haizhiyuan Intelligent Technology Co Ltd
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Qingdao Haizhiyuan Intelligent Technology Co Ltd
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Abstract

The invention relates to a traditional Chinese medicinal herbal preparation for treating ichthyophthiriasis of osteoglossum bicirrhosum, and relates to a preparation method of the traditional Chinese medicinal herbal preparation. The preparation is prepared from the following components in parts by mass: 22-34 parts of gleditsia sinensis juice, 15-22 parts of calamus, 15-22 parts of folium artemisiae argyi, 10-18 parts of torilis japonica, 7-12 parts of Pu-erh ripe tea, 10-16 parts of morning glory, 10-16 parts of herba houttuyniae, 8-18 parts of folium isatidis, 12-16 parts of Chinese gall, 12-18 parts of radix bupleuri, 13-16 parts of garlic, 11-16 parts of coptis chinensis, 7-15 parts of astragalus smicus, 7-15 parts of raw ginger, 8-13 parts of cortex phellodendri, 8-13 parts of moutan bark, 9-14 parts of rhizoma kaempferiae, 6-13 parts of fructus cnidii, 6-10 parts of bamboo salt, 5-11 parts of white vinegar and 5-11 parts of peppermint oil. The traditional Chinese medicinal herbal preparation has a high cure rate on the ichthyophthiriasis of osteoglossum bicirrhosum.

Description

A kind ofly treat Chinese herbal and crude drugs preparations of silver-colored imperial fish ichthyophthiriasis and preparation method thereof
Technical field
The invention belongs to field of Chinese herbal medicine technology, particularly relate to a kind of Chinese herbal and crude drugs preparations for the treatment of silver-colored imperial fish ichthyophthiriasis; The invention still further relates to the preparation method of the Chinese herbal and crude drugs preparations of the imperial fish ichthyophthiriasis of a kind of above-mentioned treatment silver.
Background technology
Along with the growth in the living standard of people, material life is enriched greatly, and the requirement that people live to amusement and recreation is more and more obvious, and staying at home or supporting pet fish beautiful in colour a bit in garden is best selection, takes up room hardly because raise pet fish; Economic cost can be determined according to people; Condition is relatively simple, has water.Cultivation of ornamental fish not only can cultivate the body and the mind, and cultivate one's taste, the anion discharged in water and steam also can filter and wet air, build good living environment to people.
The imperial fish of silver calls silver-colored Trichiurus haumela, silver-colored ship fish, Clerodendrum thomsonae Balf. fish, originates in the Amazon River basin of South America, the basin, the Nile in Africa, to Australia and Papua New Guinea and other places.Generally perch the puddle in tributary, and the bushes that bank is not had by water logging, sometimes can find silver-colored imperial fish in the water environment having floating grass.Rear inflow China, in south, the silver-colored imperial fish of breeding succeeds, and is one of main pet fish of China, silver-colored imperial fish Asia Southeast Asia because of edema due to wind pathogen demand quite welcome.
Ichthyophthiriasis is a kind of modal Fish parasitic disease, is mainly in the Cyprinidae and the tropical fish comparatively easy infection of Family Cichlidae in season that water temperature at the beginning of last month of spring in autumn is lower.Ichthyophthiriasis is also ichthyophthiriasis, and little melonworm polypide is spherical in shape, and whole body has draped over one's shoulders cilium, and diameter is about 0.8mm, is macroscopic small particles.When water temperature 18-23 DEG C, little melonworm often colonizes in subcutaneous, tail fin and the gill portion of fish, sucks the nutrition of Fish tissue, and stimulates fish body to secrete a large amount of mucus, therefore forms white pus bubble one by one at fish body surface, spreads all over fish whole body.Tropical fish suffer from this sick time, show and fin first occur white point, fish seem dull mind, float on the water surface, seldom movable, or pasture and water of being everlasting, sandstone side body rapidly travelling rubbing itch.Time serious, cause fish body the whole body gather white point, stopping is ingested, human body is become thin, dyspnea until death, the course of disease is generally about 5-10 days.If run under temperature shock or fish resist hypodynamic situation, silver-colored imperial fish will large-scale outbreak ichthyophthiriasis.The imperial fish ichthyophthiriasis of silver not only affects the reward property of silver-colored imperial fish, but also can cause the death of silver-colored imperial fish and then bring serious economic loss.At present, the means of usual employing for the treatment of ichthyophthiriasis change water salting or with Mercury protonitrate. or use malachite green oxalate dipping, is its limited efficiency and cure rate is low by the shortcoming of Sal immersion, can not make silver-colored imperial fish speedy recovery to health, the healing cycle is long, cannot effectively deal with problems; And with Mercury protonitrate. or too large by malachite green oxalate toxicity, not only pollute the environment, and easily cause silver-colored imperial ichthyism, in addition, Mercury protonitrate. or have very large toxicity to Corallium Japonicum Kishinouye and invertebrates with malachite green oxalate, can not directly put in poison in Corallium Japonicum Kishinouye cylinder, needs to carry out in independent quarantine cylinder.
Summary of the invention
An object of the present invention is to provide a kind of Chinese herbal and crude drugs preparations for the treatment of silver-colored imperial fish ichthyophthiriasis, and its raw material components is green pure natural material, high to silver imperial fish ichthyophthiriasis cure rate, and the cycle of healing is short, and the Health restoration of silver-colored imperial fish is fast.
In order to solve the problems of the technologies described above, the present invention by the following technical solutions, a kind of Chinese herbal and crude drugs preparations for the treatment of silver-colored imperial fish ichthyophthiriasis, be made up of each component of following masses number: Fructus Gleditsia juice 22-34 part, Rhizoma Acori Graminei 15-22 part, Folium Artemisiae Argyi 15-22 part, little surreptitiously careless 10-18 part, Folium camelliae assamicae (processed) 7-12 part, morning glory 10-16 part, Herba Houttuyniae 10-16 part, Folium Isatidis 8-18 part, Galla Chinensis 12-16 part, Radix Bupleuri 12-18 part, Bulbus Allii 13-16 part, Rhizoma Coptidis 11-16 part, Herba Astragali Melilotoidis (Herba Astragali Sinici) 7-15 part, Rhizoma Zingiberis Recens 7-15 part, Cortex Phellodendri 8-13 part, Cortex Moutan 8-13 part, Rhizoma Kaempferiae 9-14 part, Fructus Cnidii 6-13 part, bamboo salt 6-10 part, white vinegar 5-11 part, Oleum menthae 5-11 part.
Preferably, the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis of described treatment, be made up of each component of following masses number: Fructus Gleditsia juice 28-30 part, Rhizoma Acori Graminei 18-20 part, Folium Artemisiae Argyi 16-20 part, little surreptitiously careless 12-15 part, Folium camelliae assamicae (processed) 9-11 part, morning glory 12-14 part, Herba Houttuyniae 12-14 part, Folium Isatidis 10-14 part, Galla Chinensis 14-15 part, Radix Bupleuri 14-15 part, Bulbus Allii 14-15 part, Rhizoma Coptidis 13-15 part, Herba Astragali Melilotoidis (Herba Astragali Sinici) 10-12 part, Rhizoma Zingiberis Recens 10-13 part, Cortex Phellodendri 10-12 part, Cortex Moutan 10-12 part, Rhizoma Kaempferiae 11-13 part, Fructus Cnidii 8-11 part, bamboo salt 8-9 part, white vinegar 7-9 part, Oleum menthae 7-9 part.
Preferably; the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis of described treatment, is made up of each component of following masses number: Fructus Gleditsia juice 28 parts, Rhizoma Acori Graminei 19 parts, Folium Artemisiae Argyi 18 parts, little surreptitiously grass 14 parts, Folium camelliae assamicae (processed) 10 parts, 13 parts, morning glory, Herba Houttuyniae 13 parts, Folium Isatidis 12 parts, Galla Chinensis 15 parts, Radix Bupleuri 15 parts, 14 parts, Bulbus Allii, Rhizoma Coptidis 14 parts, Herba Astragali Melilotoidis (Herba Astragali Sinici) 11 parts, 12 parts, Rhizoma Zingiberis Recens, Cortex Phellodendri 11 parts, Cortex Moutan 11 parts, Rhizoma Kaempferiae 12 parts, Fructus Cnidii 10 parts, bamboo salt 8 parts, white vinegar 8 parts, Oleum menthae 8 parts.
The preparation method of described Fructus Gleditsia juice is: ground or put into juice extractor by Fructus Gleditsia and squeeze the juice, get gained juice, gained juice is Fructus Gleditsia juice.
Another object of the present invention is to provide the preparation method of the Chinese herbal and crude drugs preparations of the imperial fish ichthyophthiriasis of a kind of above-mentioned treatment silver, and the preparation method of the Chinese herbal and crude drugs preparations of the imperial fish ichthyophthiriasis of this treatment silver comprises the following steps:
(1) by Fructus Gleditsia grinding or put into juice extractor and squeeze the juice, and the Fructus Gleditsia juice of gained is taken by said ratio;
(2) take Rhizoma Acori Graminei, Folium Artemisiae Argyi by proportioning, littlely steal grass, Folium camelliae assamicae (processed) and morning glory, by Rhizoma Acori Graminei, Folium Artemisiae Argyi, littlely steal grass, the gross weight of Folium camelliae assamicae (processed) and morning glory is denoted as 1 part, take the purified water of 20 parts, at 70-80 DEG C, 2-3h is soaked in water-bath, obtains soak;
(3) boil 2h after the soak that step (2) obtains being heated to boiling, be separated and take out fried liquid, continue the purified water adding 6 parts in medical material, continue to boil 1.5h after being heated to boiling, merge twice fried liquid and be extracting solution;
(4) take Herba Houttuyniae, Folium Isatidis, Galla Chinensis, Radix Bupleuri, Bulbus Allii, Rhizoma Coptidis, Herba Astragali Melilotoidis (Herba Astragali Sinici), Rhizoma Zingiberis Recens, Cortex Phellodendri, Cortex Moutan, Rhizoma Kaempferiae and Fructus Cnidii respectively by said ratio, load ball mill grinding 2h, cross 80 mesh sieves, obtain grounds travel;
(5) grounds travel that the extracting solution that obtains of step (3) and step (4) obtain is positioned in the extraction kettle in supercritical extraction instrument, carbon dioxide is utilized to extract as medium, extraction kettle pressure is 40Mpa, extraction temperature is 45 DEG C, separator pressure 12Mpa, separator temperature is 70 DEG C, extracts 2 hours, is extracted liquid;
(6) take bamboo salt, white vinegar and Oleum menthae according to proportioning, mix with the extract of the load weighted Fructus Gleditsia juice of step (1), step (5) gained, obtain object.
The using method of the present invention when treating silver-colored imperial fish ichthyophthiriasis is as follows: water per ton pours the preparation of the present invention of 40-80ml into, within every 12 hours, changes water once, adds preparation of the present invention after changing water by same ratio, uses 4-10 days continuously.
The using method of the present invention when preventing silver-colored imperial fish ichthyophthiriasis is as follows: water per ton pours the preparation of the present invention of 10-30ml into, changes water once after 24 hours, adds preparation of the present invention after changing water by same ratio, after using 2 days continuously, stops 1 day; A circulation 5-9 cycle like this.
Each component effect of the present invention is resolved as follows:
Fructus Gleditsia has the effect of parasite killing, removing toxic substances: saponin element contained in Fructus Gleditsia is triterpene class and oligosaccharide, has antiinflammatory, antiulcer, disease-resistant change effect, also has anticancer and improves the effects such as acquired immune deficiency syndrome (AIDS) immunity.Rhizoma Acori Graminei can be dispelled epidemic disease Fructus Alpiniae Oxyphyllae, damp eliminating removing toxic substances, building body, combustion Rhizoma Acori Graminei, Folium Artemisiae Argyi, anophelifuge deinsectization, after 500 grams, Rhizoma Acori Graminei rhizome is mashed, add water 1-1.5 kilogram of infusion two hours, the stock solution of gained, is watered 3-6 kilogram after filtration, can effectively prevent and treat the insect pests such as planthopper, rice leafhopper, rice green caterpillar, aphid, red spider.Folium Artemisiae Argyi can exorcise evil spirits heal, expelling insect and relieving itching.Little grass of stealing has promoting blood circulation and detumescence, the effect of convergence parasite killing.Folium camelliae assamicae (processed) includes abundant tea polyphenols, and Folium camelliae assamicae (processed) has anticancer, inhibiting bacteria and diminishing inflammation, alleviates tobacco poisoning, alleviates the effects such as heavy metal poison, can treat bacillary dysentery.Morning glory has removing water retention by purgation diuresis, effect by expectorant, detumescence, parasite killing anthelmintic, cures mainly the diseases such as limds edema, oedema due to nephritis, cirrhotic ascites, constipation, abdominal pain due to worm stagnation.Herba Houttuyniae has heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, the effect of inducing diuresis for treating stranguria syndrome.Folium Isatidis cures mainly pyretic toxicity and sends out the diseases such as speckle, erysipelas, laryngopharynx swelling and pain, aphtha of the mouth and tongue, sore and toxic.Galla Chinensis is cold in nature, sour in the mouth, puckery, has the effects such as pathogenic fire reducing of astringing the lung, relieving diarrhea with astringents, arresting sweating hemostasis, removing dampness sore, cures mainly the diseases such as chronic cough of deficiency lung, chronic diarrhea chronic dysentery, hemorrhoidal bleeding of having blood in stool, carbuncle sore tumefacting virus, Skin wet and rotten.Radix Bupleuri has reconciling superficies and interior, effect of soothing the liver yang invigorating, can be used for treatment cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterine prolapse, menoxenia.Bulbus Allii removing toxic substances parasite killing, reducing swelling and alleviating pain, antidiarrheal dysentery relieving, controls lung, anthelmintic, and also have warming the spleen warming the stomach in addition, control swollen ulcer drug, white bald tinea skin ulcer, dysentery is had loose bowels, pulmonary tuberculosis pertussis, ascarid pinworm, eating accumulation, coldness and pain in the epigastrium, edema distension.Rhizoma Coptidis has heat clearing and damp drying, effect of eliminating fire and detoxication.Herba Astragali Melilotoidis (Herba Astragali Sinici) cures mainly removing blood stasis, hemostasia and promoting granulation, and profit can support the five internal organs, improve visual and auditory acuity, hot blast of dispelling, makes us spry and light, and food is not minded for a long time, mends people, can stop hot malaria, flat stomach of invigorating blood circulation.Rhizoma Zingiberis Recens has bactericidal effect, and can strengthen digestion power.Cortex Phellodendri has heat clearing and damp drying, and pathogenic fire purging is except steaming, and effect of detoxification sore treatment, can be used for treating damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity is knitted, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.Cortex Moutan is the dry root bark of ranunculaceae peony, bitter in the mouth, pungent, and cold nature, has the effects such as clearing away heat and cooling blood, activating blood circulation to dissipate blood stasis, reducing the asthenic fever, can be used for the treatment of to fall and flutter the pain of injury, carbuncle sore tumefacting virus.Rhizoma Kaempferiae is the dry rhizome of zingiberaceous plant Rhizoma Kaempferiae, is excavated winter, and clean, remove fibrous root, section is dried, warming middle-JIAO for eliminating dampness, promoting the circulation of QI to relieve pain; Cure mainly acute gastroenteritis, dyspepsia, cold syndrome of the stomach pain, toothache, rheumatic arthritis, traumatic injury.Fructus Cnidii is the dry mature fruit of samphire cnidium monnieri, has resisting pathogenic microbes effect, and Fructus Cnidii all has inhibitory action to acrothesium floccosum, Gypsum Fibrosum sample microspore bacterium, ulotrichy microspore bacterium; Also there is antifungic action, Antifungal activities, insecticidal action.Bamboo salt is evaporated brine day to load in triennial QINGZHU, and two ends are sealed with natural loess, take pinaster as fuel, the material extract after 1000 DEG C ~ 1500 DEG C high-temperature calcinations, has antibacterial, antiinflammatory, toxopexic effect.White vinegar has the function of dissipating blood stasis, removing toxic substances, detumescence.Oleum menthae light weight a surname is loose, has dispelling wind and heat pathogens, declares the merit of malicious rash: can be used for controlling wind heat bundle table, measles without adequate eruption; Also can treat rubella pruritus, get the effect that its rash of dispeling the wind is antipruritic.
In preparation method, crude drug purified water soaking a period of time, medical material deliquescing, cell expansion, effective ingredient is easily fried, and medical material contains starch, protein, after soaking, prevent when decocting, the starch gelatinization on medical material surface, protein coagulating, the capillary channel on blocking medical material surface, make the moisture when decocting enter not go, effective ingredient is not easily fried, affects curative effect of medication; Decoction can change the irritation effect of medicine, relatively mildly acts on silver-colored imperial fish, promotes that silver-colored imperial fish is to the absorption of medicine; Grinding makes the starch in medical material, protein is separated out more fully at subsequent step; Supercritical extraction, immersion, concentration step retain the effective ingredient in Chinese medicine of the present invention to greatest extent.
The Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention, the mechanism of action according to ichthyophthiriasis, the suitable Chinese herbal medicine selected, and organically combined, there is significant cooperative synergism effect, play the function of each component to greatest extent, and the component of the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention is environmental protection raw material, environmental sound, good to the curative effect of the imperial fish ichthyophthiriasis of silver, cure rate is high, and make the survival rate of ill silver dragon fish to more than 92%, after medication 3-5 days, silver-colored imperial fish body surface is without white point.In addition, the present invention uses safer, little to the damage of silver imperial fish, and after using the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention, silver-colored imperial fish Health restoration is fast, and medication 4-10 days, silver-colored imperial fish can recover normal activity, and ichthyophthiriasis is thoroughly cured.And the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention can not only be high to ichthyophthiriasis cure rate when silver imperial fish ichthyophthiriasis is sent out, and effectively can prevent the generation of silver-colored imperial fish ichthyophthiriasis.
Compared with prior art, the invention has the beneficial effects as follows:
(1) Fructus Gleditsia is monarch drug, has the effect of parasite killing, removing toxic substances: saponin element contained in Fructus Gleditsia is triterpene class and oligosaccharide, has antiinflammatory, antiulcer, disease-resistant change effect, also has anticancer and improves the effects such as acquired immune deficiency syndrome (AIDS) immunity.
Rhizoma Acori Graminei can be dispelled epidemic disease Fructus Alpiniae Oxyphyllae, damp eliminating removing toxic substances, building body, combustion Rhizoma Acori Graminei, Folium Artemisiae Argyi, anophelifuge deinsectization, after 500 grams, Rhizoma Acori Graminei rhizome is mashed, add water 1-1.5 kilogram of infusion two hours, the stock solution of gained, is watered 3-6 kilogram after filtration, can effectively prevent and treat the insect pests such as planthopper, rice leafhopper, rice green caterpillar, aphid, red spider.Folium Artemisiae Argyi can exorcise evil spirits heal, expelling insect and relieving itching.Little grass of stealing has promoting blood circulation and detumescence, the effect of convergence parasite killing.Folium camelliae assamicae (processed) includes abundant tea polyphenols, and Folium camelliae assamicae (processed) has anticancer, inhibiting bacteria and diminishing inflammation, alleviates tobacco poisoning, alleviates the effects such as heavy metal poison, can treat bacillary dysentery.Morning glory has removing water retention by purgation diuresis, effect by expectorant, detumescence, parasite killing anthelmintic, cures mainly the diseases such as limds edema, oedema due to nephritis, cirrhotic ascites, constipation, abdominal pain due to worm stagnation.Rhizoma Acori Graminei, Folium Artemisiae Argyi, little surreptitiously grass, Folium camelliae assamicae (processed) and morning glory are ministerial drug.
Herba Houttuyniae has heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, the effect of inducing diuresis for treating stranguria syndrome.Folium Isatidis cures mainly pyretic toxicity and sends out the diseases such as speckle, erysipelas, laryngopharynx swelling and pain, aphtha of the mouth and tongue, sore and toxic.Galla Chinensis is cold in nature, sour in the mouth, puckery, has the effects such as pathogenic fire reducing of astringing the lung, relieving diarrhea with astringents, arresting sweating hemostasis, removing dampness sore, cures mainly the diseases such as chronic cough of deficiency lung, chronic diarrhea chronic dysentery, hemorrhoidal bleeding of having blood in stool, carbuncle sore tumefacting virus, Skin wet and rotten.Radix Bupleuri has reconciling superficies and interior, effect of soothing the liver yang invigorating, can be used for treatment cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterine prolapse, menoxenia.Bamboo salt is evaporated brine day to load in triennial QINGZHU, and two ends are sealed with natural loess, take pinaster as fuel, the material extract after 1000 DEG C ~ 1500 DEG C high-temperature calcinations, has antibacterial, antiinflammatory, toxopexic effect.White vinegar has the function of dissipating blood stasis, removing toxic substances, detumescence.Oleum menthae light weight a surname is loose, has dispelling wind and heat pathogens, declares the merit of malicious rash: can be used for controlling wind heat bundle table, measles without adequate eruption; Also can treat rubella pruritus, get the effect that its rash of dispeling the wind is antipruritic.Herba Houttuyniae, Folium Isatidis, Galla Chinensis, Radix Bupleuri, bamboo salt, white vinegar and Oleum menthae are adjuvant drug.
Bulbus Allii removing toxic substances parasite killing, reducing swelling and alleviating pain, antidiarrheal dysentery relieving, controls lung, anthelmintic, and also have warming the spleen warming the stomach in addition, control swollen ulcer drug, white bald tinea skin ulcer, dysentery is had loose bowels, pulmonary tuberculosis pertussis, ascarid pinworm, eating accumulation, coldness and pain in the epigastrium, edema distension.Rhizoma Coptidis has heat clearing and damp drying, effect of eliminating fire and detoxication.Herba Astragali Melilotoidis (Herba Astragali Sinici) cures mainly removing blood stasis, hemostasia and promoting granulation, and profit can support the five internal organs, improve visual and auditory acuity, hot blast of dispelling, makes us spry and light, and food is not minded for a long time, mends people, can stop hot malaria, flat stomach of invigorating blood circulation.Rhizoma Zingiberis Recens has bactericidal effect, and can strengthen digestion power.Cortex Phellodendri has heat clearing and damp drying, and pathogenic fire purging is except steaming, and effect of detoxification sore treatment, can be used for treating damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity is knitted, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.Cortex Moutan is the dry root bark of ranunculaceae peony, bitter in the mouth, pungent, and cold nature, has the effects such as clearing away heat and cooling blood, activating blood circulation to dissipate blood stasis, reducing the asthenic fever, can be used for the treatment of to fall and flutter the pain of injury, carbuncle sore tumefacting virus.Rhizoma Kaempferiae is the dry rhizome of zingiberaceous plant Rhizoma Kaempferiae, is excavated winter, and clean, remove fibrous root, section is dried, warming middle-JIAO for eliminating dampness, promoting the circulation of QI to relieve pain; Cure mainly acute gastroenteritis, dyspepsia, cold syndrome of the stomach pain, toothache, rheumatic arthritis, traumatic injury.Fructus Cnidii is the dry mature fruit of samphire cnidium monnieri, has resisting pathogenic microbes effect, and Fructus Cnidii all has inhibitory action to acrothesium floccosum, Gypsum Fibrosum sample microspore bacterium, ulotrichy microspore bacterium; Also there is antifungic action, Antifungal activities, insecticidal action.Bulbus Allii, Rhizoma Coptidis, Herba Astragali Melilotoidis (Herba Astragali Sinici), Rhizoma Zingiberis Recens, Cortex Phellodendri, Cortex Moutan, Rhizoma Kaempferiae and Fructus Cnidii are for making medicine.
(2) Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention, is the Chinese herbal medicine selected according to the mechanism of action of ichthyophthiriasis, and is organically combined, have significant cooperative synergism effect, play the function of each component to greatest extent.
(3) component of the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention is environmental protection raw material; environmental sound; use safer; very little to the damage of silver imperial fish; after using the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention, silver-colored imperial fish Health restoration is fast, medication 4-10 days; the imperial fish of silver just recovers normal activity, and ichthyophthiriasis is thoroughly cured.
(4) curative effect of Chinese herbal and crude drugs preparations to the imperial fish ichthyophthiriasis of silver of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention is good, and cure rate is high, and make the survival rate of ill silver dragon fish to more than 92%, after medication 3-5 days, silver-colored imperial fish body surface is without white point.In addition, the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention can not only be high to ichthyophthiriasis cure rate when silver imperial fish ichthyophthiriasis is sent out, and effectively can prevent the generation of silver-colored imperial fish ichthyophthiriasis.
(5) in preparation method, crude drug purified water soaking a period of time, medical material deliquescing, cell expansion, effective ingredient is easily fried, and medical material contains starch, protein, after soaking, prevent when decocting, the starch gelatinization on medical material surface, protein coagulating, the capillary channel on blocking medical material surface, make the moisture when decocting enter not go, effective ingredient is not easily fried, affects curative effect of medication; Decoction can change the irritation effect of medicine, relatively mildly acts on silver-colored imperial fish, promotes that silver-colored imperial fish is to the absorption of medicine; Grinding makes the starch in medical material, protein is separated out more fully at subsequent step; Supercritical extraction, immersion, concentration step retain the effective ingredient in Chinese medicine of the present invention to greatest extent.
Detailed description of the invention
Following embodiment is convenient to understand the present invention better, but does not limit the present invention.Experimental technique in following embodiment, if no special instructions, is conventional method.
Embodiment 1
In the present invention's first detailed description of the invention, feed ingredient and preparation method thereof is as follows:
Treat a Chinese herbal and crude drugs preparations for silver-colored imperial fish ichthyophthiriasis, be made up of each component of following masses number: Fructus Gleditsia juice 22 parts, Rhizoma Acori Graminei 15 parts, Folium Artemisiae Argyi 15 parts, little surreptitiously grass 12 parts, Folium camelliae assamicae (processed) 12 parts, 12 parts, morning glory, Herba Houttuyniae 10 parts, Folium Isatidis 8 parts, Galla Chinensis 12 parts, Radix Bupleuri 12 parts, 13 parts, Bulbus Allii, Rhizoma Coptidis 11 parts, Herba Astragali Melilotoidis (Herba Astragali Sinici) 7 parts, 7 parts, Rhizoma Zingiberis Recens, Cortex Phellodendri 8 parts, Cortex Moutan 13 parts, Rhizoma Kaempferiae 14 parts, Fructus Cnidii 6 parts, bamboo salt 6 parts, white vinegar 5 parts, Oleum menthae 5 parts.
The preparation method of the Chinese herbal and crude drugs preparations of the imperial fish ichthyophthiriasis of above-mentioned treatment silver comprises the following steps:
(1) by Fructus Gleditsia grinding or put into juice extractor and squeeze the juice, and the Fructus Gleditsia juice of gained is taken by said ratio;
(2) take Rhizoma Acori Graminei, Folium Artemisiae Argyi by proportioning, littlely steal grass, Folium camelliae assamicae (processed) and morning glory, by Rhizoma Acori Graminei, Folium Artemisiae Argyi, littlely steal grass, the gross weight of Folium camelliae assamicae (processed) and morning glory is denoted as 1 part, take the purified water of 20 parts, at 70-80 DEG C, 2-3h is soaked in water-bath, obtains soak;
(3) boil 2h after the soak that step (2) obtains being heated to boiling, be separated and take out fried liquid, continue the purified water adding 6 parts in medical material, continue to boil 1.5h after being heated to boiling, merge twice fried liquid and be extracting solution;
(4) take Herba Houttuyniae, Folium Isatidis, Galla Chinensis, Radix Bupleuri, Bulbus Allii, Rhizoma Coptidis, Herba Astragali Melilotoidis (Herba Astragali Sinici), Rhizoma Zingiberis Recens, Cortex Phellodendri, Cortex Moutan, Rhizoma Kaempferiae and Fructus Cnidii respectively by said ratio, load ball mill grinding 2h, cross 80 mesh sieves, obtain grounds travel;
(5) grounds travel that the extracting solution that obtains of step (3) and step (4) obtain is positioned in the extraction kettle in supercritical extraction instrument, carbon dioxide is utilized to extract as medium, extraction kettle pressure is 40Mpa, extraction temperature is 45 DEG C, separator pressure 12Mpa, separator temperature is 70 DEG C, extracts 2 hours, is extracted liquid;
(6) take bamboo salt, white vinegar and Oleum menthae according to proportioning, mix with the extract of the load weighted Fructus Gleditsia juice of step (1), step (5) gained, obtain object.
Embodiment 2
In the present invention's second detailed description of the invention, feed ingredient and preparation method thereof is as follows:
Treat a Chinese herbal and crude drugs preparations for silver-colored imperial fish ichthyophthiriasis, be made up of each component of following masses number: Fructus Gleditsia juice 28 parts, Rhizoma Acori Graminei 19 parts, Folium Artemisiae Argyi 18 parts, little surreptitiously grass 14 parts, Folium camelliae assamicae (processed) 10 parts, 13 parts, morning glory, Herba Houttuyniae 13 parts, Folium Isatidis 12 parts, Galla Chinensis 15 parts, Radix Bupleuri 15 parts, 14 parts, Bulbus Allii, Rhizoma Coptidis 14 parts, Herba Astragali Melilotoidis (Herba Astragali Sinici) 11 parts, 12 parts, Rhizoma Zingiberis Recens, Cortex Phellodendri 11 parts, Cortex Moutan 11 parts, Rhizoma Kaempferiae 12 parts, Fructus Cnidii 10 parts, bamboo salt 8 parts, white vinegar 8 parts, Oleum menthae 8 parts.
The preparation method of the Chinese herbal and crude drugs preparations of the imperial fish ichthyophthiriasis for the treatment of silver of the present embodiment is with embodiment 1.
Embodiment 3
In the present invention's the 3rd detailed description of the invention, feed ingredient and preparation method thereof is as follows:
Treat a Chinese herbal and crude drugs preparations for silver-colored imperial fish ichthyophthiriasis, be made up of each component of following masses number: Fructus Gleditsia juice 29 parts, Rhizoma Acori Graminei 20 parts, Folium Artemisiae Argyi 22 parts, little surreptitiously grass 10 parts, Folium camelliae assamicae (processed) 10 parts, 10 parts, morning glory, Herba Houttuyniae 14 parts, Folium Isatidis 14 parts, Galla Chinensis 16 parts, Radix Bupleuri 18 parts, 14 parts, Bulbus Allii, Rhizoma Coptidis 13 parts, Herba Astragali Melilotoidis (Herba Astragali Sinici) 10 parts, 12 parts, Rhizoma Zingiberis Recens, Cortex Phellodendri 12 parts, Cortex Moutan 10 parts, Rhizoma Kaempferiae 9 parts, Fructus Cnidii 11 parts, bamboo salt 10 parts, white vinegar 9 parts, Oleum menthae 9 parts.
The preparation method of the Chinese herbal and crude drugs preparations of the imperial fish ichthyophthiriasis for the treatment of silver of the present embodiment is with embodiment 1.
Embodiment 4
In the present invention's the 4th detailed description of the invention, feed ingredient and preparation method thereof is as follows:
Treat a Chinese herbal and crude drugs preparations for silver-colored imperial fish ichthyophthiriasis, be made up of each component of following masses number: Fructus Gleditsia juice 34 parts, Rhizoma Acori Graminei 22 parts, Folium Artemisiae Argyi 22 parts, little surreptitiously grass 18 parts, Folium camelliae assamicae (processed) 11 parts, 14 parts, morning glory, Herba Houttuyniae 16 parts, Folium Isatidis 18 parts, Galla Chinensis 15 parts, Radix Bupleuri 16 parts, 16 parts, Bulbus Allii, Rhizoma Coptidis 15 parts, Herba Astragali Melilotoidis (Herba Astragali Sinici) 15 parts, 13 parts, Rhizoma Zingiberis Recens, Cortex Phellodendri 13 parts, Cortex Moutan 12 parts, Rhizoma Kaempferiae 13 parts, Fructus Cnidii 13 parts, bamboo salt 8 parts, white vinegar 11 parts, Oleum menthae 11 parts.
The preparation method of the Chinese herbal and crude drugs preparations of the imperial fish ichthyophthiriasis for the treatment of silver of the present embodiment is with embodiment 1.
Embodiment 5
In the present invention's the 5th detailed description of the invention, feed ingredient and preparation method thereof is as follows:
Treat a Chinese herbal and crude drugs preparations for silver-colored imperial fish ichthyophthiriasis, be made up of each component of following masses number: Fructus Gleditsia juice 30 parts, Rhizoma Acori Graminei 18 parts, Folium Artemisiae Argyi 20 parts, little surreptitiously grass 15 parts, Folium camelliae assamicae (processed) 9 parts, 16 parts, morning glory, Herba Houttuyniae 10 parts, Folium Isatidis 10 parts, Galla Chinensis 14 parts, Radix Bupleuri 14 parts, 15 parts, Bulbus Allii, Rhizoma Coptidis 16 parts, Herba Astragali Melilotoidis (Herba Astragali Sinici) 12 parts, 10 parts, Rhizoma Zingiberis Recens, Cortex Phellodendri 10 parts, Cortex Moutan 8 parts, Rhizoma Kaempferiae 11 parts, Fructus Cnidii 8 parts, bamboo salt 9 parts, white vinegar 7 parts, Oleum menthae 7 parts.
The preparation method of the Chinese herbal and crude drugs preparations of the imperial fish ichthyophthiriasis for the treatment of silver of the present embodiment is with embodiment 1.
Embodiment 6
In the present invention's the 6th detailed description of the invention, feed ingredient and preparation method thereof is as follows:
Treat a Chinese herbal and crude drugs preparations for silver-colored imperial fish ichthyophthiriasis, be made up of each component of following masses number: Fructus Gleditsia juice 25 parts, Rhizoma Acori Graminei 16 parts, Folium Artemisiae Argyi 16 parts, little surreptitiously grass 11 parts, Folium camelliae assamicae (processed) 7 parts, 10 parts, morning glory, Herba Houttuyniae 12 parts, Folium Isatidis 9 parts, Galla Chinensis 12 parts, Radix Bupleuri 15 parts, 13 parts, Bulbus Allii, Rhizoma Coptidis 12 parts, Herba Astragali Melilotoidis (Herba Astragali Sinici) 9 parts, 15 parts, Rhizoma Zingiberis Recens, Cortex Phellodendri 9 parts, Cortex Moutan 13 parts, Rhizoma Kaempferiae 9 parts, Fructus Cnidii 8 parts, bamboo salt 8 parts, white vinegar 5 parts, Oleum menthae 7 parts.
The preparation method of the Chinese herbal and crude drugs preparations of the imperial fish ichthyophthiriasis for the treatment of silver of the present embodiment is with embodiment 1.
Experimental result
In order to verify therapeutic effect of the present invention, within 2013 and 2014, in fishing ground, Qingdao, the silver dragon fish suffering from ichthyophthiriasis is tested.The using method of the present invention when treating silver-colored imperial fish ichthyophthiriasis is as follows: water per ton pours the preparation of the present invention of 40-80ml into, within every 12 hours, changes water once, adds preparation of the present invention after changing water by same ratio, uses 4-10 days continuously.As a control group with the Therapeutic Method of Sal immersion (water per ton puts into the Sal of 0.5kg-1kg) simultaneously.Experimental result shows, after medication 3-5 days, silver-colored imperial fish body surface is without white point, medication 4-10 days, and silver-colored imperial fish can recover normal activity, and ichthyophthiriasis is thoroughly cured.Result of the test is in table 1:
The Chinese herbal and crude drugs preparations therapeutic effect situation of the silver-colored imperial fish ichthyophthiriasis of table 1 treatment of the present invention
From table 1, the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention is when treating silver-colored imperial fish ichthyophthiriasis, and curative effect is good, and cure rate is high, makes the survival rate of ill silver dragon fish to more than 92%.In addition, the present invention uses safer, little to the damage of silver imperial fish; after using the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention, silver-colored imperial fish Health restoration is fast, medication 4-10 days; ichthyophthiriasis is thoroughly cured, and show as silver-colored imperial fish and recover normal activity, trip appearance is strong and vigorous.
In addition, the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention can not only be high to ichthyophthiriasis cure rate when silver imperial fish ichthyophthiriasis is sent out, and effectively can prevent the generation of silver-colored imperial fish ichthyophthiriasis, in order to verify preventive effect of the present invention, within 2014, in fishing ground, Qingdao, the test preventing ichthyophthiriasis is carried out to the imperial fish of silver, experimental period is 8 months, normally to raise group for matched group.The using method of the present invention when preventing silver-colored imperial fish ichthyophthiriasis is as follows: water per ton pours the preparation of the present invention of 10-30ml into, changes water once after 24 hours, adds preparation of the present invention after changing water by same ratio, after using 2 days continuously, stops 1 day.7 cycles of circulation like this.The results are shown in Table 2:
The effect situation of the Chinese herbal and crude drugs preparations prevention ichthyophthiriasis of the silver-colored imperial fish ichthyophthiriasis of table 2 treatment of the present invention
From table 2, the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of of the present invention effectively can reduce the incidence rate of silver-colored imperial fish ichthyophthiriasis.
The above is only the preferred embodiment of the present invention, is noted that for those skilled in the art, and under the premise without departing from the principles of the invention, can also make some improvement, these improvement should be considered as protection scope of the present invention.

Claims (6)

1. treat the Chinese herbal and crude drugs preparations of silver-colored imperial fish ichthyophthiriasis for one kind, it is characterized in that: be made up of each component of following masses number: Fructus Gleditsia juice 22-34 part, Rhizoma Acori Graminei 15-22 part, Folium Artemisiae Argyi 15-22 part, little surreptitiously careless 10-18 part, Folium camelliae assamicae (processed) 7-12 part, morning glory 10-16 part, Herba Houttuyniae 10-16 part, Folium Isatidis 8-18 part, Galla Chinensis 12-16 part, Radix Bupleuri 12-18 part, Bulbus Allii 13-16 part, Rhizoma Coptidis 11-16 part, Herba Astragali Melilotoidis (Herba Astragali Sinici) 7-15 part, Rhizoma Zingiberis Recens 7-15 part, Cortex Phellodendri 8-13 part, Cortex Moutan 8-13 part, Rhizoma Kaempferiae 9-14 part, Fructus Cnidii 6-13 part, bamboo salt 6-10 part, white vinegar 5-11 part, Oleum menthae 5-11 part.
2. the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of according to claim 1, it is characterized in that: the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis of described treatment, be made up of each component of following masses number: Fructus Gleditsia juice 28-30 part, Rhizoma Acori Graminei 18-20 part, Folium Artemisiae Argyi 16-20 part, little surreptitiously careless 12-15 part, Folium camelliae assamicae (processed) 9-11 part, morning glory 12-14 part, Herba Houttuyniae 12-14 part, Folium Isatidis 10-14 part, Galla Chinensis 14-15 part, Radix Bupleuri 14-15 part, Bulbus Allii 14-15 part, Rhizoma Coptidis 13-15 part, Herba Astragali Melilotoidis (Herba Astragali Sinici) 10-12 part, Rhizoma Zingiberis Recens 10-13 part, Cortex Phellodendri 10-12 part, Cortex Moutan 10-12 part, Rhizoma Kaempferiae 11-13 part, Fructus Cnidii 8-11 part, bamboo salt 8-9 part, white vinegar 7-9 part, Oleum menthae 7-9 part.
3. the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis for the treatment of according to claim 1, it is characterized in that: the Chinese herbal and crude drugs preparations of the silver-colored imperial fish ichthyophthiriasis of described treatment, be made up of each component of following masses number: Fructus Gleditsia juice 28 parts, Rhizoma Acori Graminei 19 parts, Folium Artemisiae Argyi 18 parts, little surreptitiously grass 14 parts, Folium camelliae assamicae (processed) 10 parts, 13 parts, morning glory, Herba Houttuyniae 13 parts, Folium Isatidis 12 parts, Galla Chinensis 15 parts, Radix Bupleuri 15 parts, 14 parts, Bulbus Allii, Rhizoma Coptidis 14 parts, Herba Astragali Melilotoidis (Herba Astragali Sinici) 11 parts, 12 parts, Rhizoma Zingiberis Recens, Cortex Phellodendri 11 parts, Cortex Moutan 11 parts, Rhizoma Kaempferiae 12 parts, Fructus Cnidii 10 parts, bamboo salt 8 parts, white vinegar 8 parts, Oleum menthae 8 parts.
4. a preparation method for the Chinese herbal and crude drugs preparations of the imperial fish ichthyophthiriasis for the treatment of silver according to any one of claim 1-3, is characterized in that: comprise the following steps:
(1) by Fructus Gleditsia grinding or put into juice extractor and squeeze the juice, and the Fructus Gleditsia juice of gained is taken by said ratio;
(2) take Rhizoma Acori Graminei, Folium Artemisiae Argyi by proportioning, littlely steal grass, Folium camelliae assamicae (processed) and morning glory, by Rhizoma Acori Graminei, Folium Artemisiae Argyi, littlely steal grass, the gross weight of Folium camelliae assamicae (processed) and morning glory is denoted as 1 part, take the purified water of 20 parts, at 70-80 DEG C, 2-3h is soaked in water-bath, obtains soak;
(3) boil 2h after the soak that step (2) obtains being heated to boiling, be separated and take out fried liquid, continue the purified water adding 6 parts in medical material, continue to boil 1.5h after being heated to boiling, merge twice fried liquid and be extracting solution;
(4) take Herba Houttuyniae, Folium Isatidis, Galla Chinensis, Radix Bupleuri, Bulbus Allii, Rhizoma Coptidis, Herba Astragali Melilotoidis (Herba Astragali Sinici), Rhizoma Zingiberis Recens, Cortex Phellodendri, Cortex Moutan, Rhizoma Kaempferiae and Fructus Cnidii respectively by said ratio, load ball mill grinding 2h, cross 80 mesh sieves, obtain grounds travel;
(5) grounds travel that the extracting solution that obtains of step (3) and step (4) obtain is positioned in the extraction kettle in supercritical extraction instrument, carbon dioxide is utilized to extract as medium, extraction kettle pressure is 40Mpa, extraction temperature is 45 DEG C, separator pressure 12Mpa, separator temperature is 70 DEG C, extracts 2 hours, is extracted liquid;
(6) take bamboo salt, white vinegar and Oleum menthae according to proportioning, mix with the extract of the load weighted Fructus Gleditsia juice of step (1), step (5) gained, obtain object.
5. the using method of Chinese herbal and crude drugs preparations when treating silver-colored imperial fish ichthyophthiriasis of the imperial fish ichthyophthiriasis for the treatment of silver according to any one of a claim 1-3, it is characterized in that: water per ton pours the preparation of the present invention of 40-80ml into, within every 12 hours, change water once, add preparation of the present invention by same ratio after changing water, use 4-10 days continuously.
6. the using method of Chinese herbal and crude drugs preparations when preventing silver-colored imperial fish ichthyophthiriasis of the imperial fish ichthyophthiriasis for the treatment of silver according to any one of a claim 1-3, it is characterized in that: water per ton pours the preparation of the present invention of 10-30ml into, water is changed once after 24 hours, preparation of the present invention is added by same ratio after changing water, continuous use, after 2 days, stops 1 day; A circulation 5-9 cycle like this.
CN201510585788.1A 2015-09-15 2015-09-15 Traditional Chinese medicinal herbal preparation for treating ichthyophthiriasis of osteoglossum bicirrhosum Pending CN105169318A (en)

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CN106138822A (en) * 2016-08-11 2016-11-23 开县佳隆农业开发有限公司 A kind of compositions treating pincers fish ichthyophthiriasis
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Application publication date: 20151223