CN106138822A - A kind of compositions treating pincers fish ichthyophthiriasis - Google Patents

A kind of compositions treating pincers fish ichthyophthiriasis Download PDF

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Publication number
CN106138822A
CN106138822A CN201610657334.5A CN201610657334A CN106138822A CN 106138822 A CN106138822 A CN 106138822A CN 201610657334 A CN201610657334 A CN 201610657334A CN 106138822 A CN106138822 A CN 106138822A
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parts
group
experiment
fici pumilae
pincers
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CN201610657334.5A
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张文佳
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Kaixian Jialong Agricultural Development Co Ltd
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Kaixian Jialong Agricultural Development Co Ltd
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Priority to CN201610657334.5A priority Critical patent/CN106138822A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/85—Verbenaceae (Verbena family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

Abstract

This patent belongs to aquaculture field, specifically discloses a kind of compositions treating pincers fish ichthyophthiriasis, according to mass fraction meter, including 10 14 parts of Caulis fici pumilae (Fructus Fici Pumilae) juice, 68 parts of Kalopanax septemlobum tree, Paederus densipennis Bernh. 57 parts, Herba Setariae viridis 24 parts.Said composition can cure pincers fish ichthyophthiriasis, and is difficult to recurrence.

Description

A kind of compositions treating pincers fish ichthyophthiriasis
Technical field
The present invention relates to aquaculture field, be specifically related to a kind of compositions treating pincers fish ichthyophthiriasis.
Background technology
Pincers fish, is again channel catfish, has meat thickness stingless, and skin sauteed pork is tender, the feature that fertile taste is dense.The nutriture value of pincers fish Be worth high, there is the feature of benefit the freshest, big, can spleen reinforcing diuretic, ventilation relieving distension, tonifying YIN tonifying YANG, the qi-restoratives that nourishes blood, the kidney invigorating of nourishing heart, right Edema, tinea pedis, waist soreness, hemorrhoid, tinea scabies, otalgia, trachoma have certain dietary function, the most also enrich blood lactogenic, in advance Anti-measles, treat chronic nephritis, to prevent and treat pulmonary tuberculosis useful.
Ichthyophthiriasis is a kind of parasitic disease of pincers fish, and ichthyophthiriasis is also named ichthyophthiriasis, little melonworm polypide (lchthyophthirius multifiliis) is spherical in shape, and whole body has draped over one's shoulders cilium, diameter about 0.8mm, for macroscopic little White point.In the case of water temperature 18-23 DEG C, little melonworm often colonizes in subcutaneous, tail fin and the gill portion of fish, sucks the battalion of Fish tissue Support, and stimulate fish body to secrete a large amount of mucus, therefore form white pus bubble one by one at fish body surface, spread all over fish whole body.Sick fish swimming Slowly, food declines, and has lurid ascites to produce, and this is sick the most concurrent with other bacterial disease.This disease mortality rate of fish exists About 20%.
Being that fish and shrimp poison gram spice takes orally for preventing and treating the common method of pincers fish ichthyophthiriasis, be used in conjunction five days, PV bacterium is praised or water Product goes out poison essence sterilization water body, and the state of an illness is available effective to be controlled.But this method can not thoroughly kill little melonworm, easily makes Ichthyophthiriasis recurs.
Summary of the invention
It is an object of the invention to provide a kind of compositions treating pincers fish ichthyophthiriasis, said composition can cure pincers roe Point disease, and it is difficult to recurrence.
For reaching above-mentioned purpose, the base case of the present invention is: a kind of compositions treating pincers fish ichthyophthiriasis, according to quality Number meter, including Caulis fici pumilae (Fructus Fici Pumilae) juice 10-14 part, Kalopanax septemlobum tree 6-8 part, Paederus densipennis Bernh. 5-7 part, Herba Setariae viridis 2-4 part.
Caulis fici pumilae (Fructus Fici Pumilae) juice is the milk of moraceae plants Caulis fici pumilae (Fructus Fici Pumilae)；There is wind dispelling insecticide antipruritic；Effect of tonifying YANG controlling nocturnal emission with astringent drugs；Main vitiligo, Scrofula infections, scabies pruritus, warty vegetation, sexual impotence, seminal emission.Cortex Kalopanacis is the bark of Araliaceae Kalopanax septemlobum；Have and dispel the wind, dehumidifying, kill Worm, the effect invigorated blood circulation；Dispelling the wind and dampness pathogens arthralgia pain, waist and knee, carbuncle, skin ulcer tinea.Paederus densipennis Bernh. is that Insecta coleoptera Yin Chi mesh section hirsutism is hidden Wing worm Paederus densipennis Bernh., is used as medicine with Scorpio；There is removing toxic substances, parasite killing, antipruritic effect；Cure mainly nerve Property dermatitis, tinea skin ulcer.Herba Setariae viridis is the herb of grass family millet Herba Setariae viridis Setaria faberii Herrm., There is heat clearing away disappear infantile malnutrition, effect of killing parasites for relieving itching.
The program have the beneficial effect that one is the effect with killing parasites for relieving itching, little melonworm can not only be killed, and alleviate The malaise symptoms of ill pincers fish；Two is that the effect treated and clamp fish ichthyophthiriasis is notable；Three is non-relapse after healing.
Prioritization scheme one: the optimization as to base case: according to mass fraction meter, also comprises Folium Callicarpae Formosanae 6-8 part, greatly tiger Auricled Hedyotis Herb 4-6 part.Folium Callicarpae Formosanae is the leaf of Verbenaceae Folium Callicarpae Macrophyllae Callicarpa macrophylla vahl；Only have Blood antiinflammatory, effect of dissipating blood stasis for subsidence of swelling；, traumatic hemorrhage, epistaxis, gingiva bleeding gingival hemorrhage hemorrhage for the expensive infections of stomach and duodenum, sprain swollen Bitterly, suppurative skin ulcer, burn, influenza.Chrysosplenium Hydrocotylifolium Levl. Et Van. is the herb of saxifragaceae plant Chrysosplenium Hydrocotylifolium Levl. Et Van.；There is heat clearing away solution Poison, expelling pathogenic wind from the body surface.Control urticaria, effect of furuncle.This programme is advantageously in the recovery from illness of pincers fish damaged skin.
Prioritization scheme two: the optimization as to prioritization scheme one: according to mass fraction meter, also comprises car Mulberry son's 5-7 part, pigtail Sub-grass roots 5-7 part.Car Mulberry son is Meliaceae car Mulberry son Dodonaea viscosa (L.) Jacq., is used as medicine with leaf, flower, fruit or Herb； There is removing toxic substances, antiinflammatory, antipruritic effect.Radix desmodiik microphylli is the root of leguminous plant Herba desmodii microphylli；There is clearing away heat-damp and promoting diuresis, hemostasis, Effect of dredging collateral；Harness the Yellow River subcutaneous ulcer, dysentery, urine leaching pain, rheumatalgia, spitting of blood, metrorrhagia, leucorrhea, hemorrhoid, traumatic injury.This programme increases Add effect of antiinflammatory, desirably prevented to be infected by bacterial at pincers fish damaged skin, cause other diseases.
Prioritization scheme three: the optimization as to prioritization scheme two: according to mass fraction meter, is by 13 parts of Caulis fici pumilae (Fructus Fici Pumilae) juice, Kalopanax septemlobum Set 7 parts, Paederus densipennis Bernh. 6 parts, Herba Setariae viridis 3 parts, Folium Callicarpae Formosanae 7 parts, Chrysosplenium Hydrocotylifolium Levl. Et Van. 5 parts, car Mulberry young 6 parts, Radix desmodiik microphylli 6 parts, monomer The stamen Radix Astragali 7 parts, Endothelium corneum Anseris domestica 5 parts composition.Radix Astragali is pulse family Radix Astragali Astragalus monadelphus Bunge, is used as medicine with root；There is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, effect of expelling pus and promoting granulation；Weak for the deficiency of vital energy, lack of appetite is just Half congealed, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and bursts for a long time and does not holds back, and blood deficiency dull yellowish colored skin is interior Heat is quenched one's thirst；Chronic nephritis proteinuria, diabetes.Endothelium corneum Anseris domestica is the gizzard inwall of Anatidae animal goose；There is spleen invigorating dysentery relieving, aid digestion Effect.This programme is conducive to increasing the appetite of ill pincers fish, promotes that it is taken food, so supplements enough nutrition, advantageously Get well in pincers fish.
Detailed description of the invention
Below by detailed description of the invention, the present invention is further detailed explanation:
Experiment one: Setup Experiments blank group, matched group, experiment A group, experiment B group, experiment C group, experiment D group, experiment E group, Experiment F group and experiment G group.Each group with an independent culturing pool.The sick fish that 450 tails suffer from ichthyophthiriasis the most all assigns to 9 In individual group, often organize 50 tails.Often organize mixed feed of all throwing something and feeding, compound feed prescription: fish flour 30%, rape cake 23%, soybean cake 20%, secondary Powder 15%, Testa oryzae 10%, food attractant-growth promoting additive 2%.Outside divided by lower process difference, remaining condition is the most identical:
Blank group: not treated with medicaments.
Matched group: fish and shrimp poison gram is mixed mixed feed and taken orally, once a day, is used in conjunction five days；Aquatic product go out poison essence sterilization water body, often It is once used in conjunction five days.
Experiment A group is to experiment G group: compositions adds the water of 5 times of volumes, decocts compositions according to the method for decocting herb, Medicinal liquid and medicinal residues；By medicinal liquid according to 0.7L/m3Consumption splash full pond, every day 1 time, continuous 5 days；Powder beaten by medicinal residues, by medicinal residues powder With mixed feed according to the ratio of 1:11 throw something and feed pincers fish, every day 1 time, continuous 5 days.
Experiment A group: compositions, according to mass fraction meter, is by 10 parts of Caulis fici pumilae (Fructus Fici Pumilae) juice, 8 parts of Kalopanax septemlobum tree, Paederus densipennis Bernh. 5 parts, towser Tail 4 parts of compositions of grass.
Experiment B group: compositions, according to mass fraction meter, is by 14 parts of Caulis fici pumilae (Fructus Fici Pumilae) juice, 6 parts of Kalopanax septemlobum tree, Paederus densipennis Bernh. 7 parts, towser Tail 2 parts of compositions of grass.
Experiment C group: compositions, according to mass fraction meter, is by 11 parts of Caulis fici pumilae (Fructus Fici Pumilae) juice, 6.2 parts of Kalopanax septemlobum tree, Paederus densipennis Bernh. 5.7 parts, Herba Setariae viridis 2.2 parts, Folium Callicarpae Formosanae 6 parts, Chrysosplenium Hydrocotylifolium Levl. Et Van. 6 parts composition.
Experiment D group: compositions, according to mass fraction meter, is by 12 parts of Caulis fici pumilae (Fructus Fici Pumilae) juice, 7.5 parts of Kalopanax septemlobum tree, Paederus densipennis Bernh. 6.3 parts, Herba Setariae viridis 2.6 parts, Folium Callicarpae Formosanae 8 parts, Chrysosplenium Hydrocotylifolium Levl. Et Van. 4 parts composition.
Experiment E group: compositions, according to mass fraction meter, is by 10.7 parts of Caulis fici pumilae (Fructus Fici Pumilae) juice, 6.6 parts of Kalopanax septemlobum tree, Paederus densipennis Bernh. 6.7 Part, Herba Setariae viridis 3.4 parts, Folium Callicarpae Formosanae 6.5 parts, Chrysosplenium Hydrocotylifolium Levl. Et Van. 4.4 parts, young 5 parts of car Mulberry, Radix desmodiik microphylli 7 parts form.
Experiment F group: compositions, according to mass fraction meter, is by 11.4 parts of Caulis fici pumilae (Fructus Fici Pumilae) juice, 7.3 parts of Kalopanax septemlobum tree, Paederus densipennis Bernh. 5.2 Part, Herba Setariae viridis 3.6 parts, Folium Callicarpae Formosanae 7.4 parts, Chrysosplenium Hydrocotylifolium Levl. Et Van. 5.6 parts, young 7 parts of car Mulberry, Radix desmodiik microphylli 5 parts form.
Experiment G group: compositions, according to mass fraction meter, is by 13 parts of Caulis fici pumilae (Fructus Fici Pumilae) juice, 7 parts of Kalopanax septemlobum tree, Paederus densipennis Bernh. 6 parts, towser Tail grass 3 parts, Folium Callicarpae Formosanae 7 parts, Chrysosplenium Hydrocotylifolium Levl. Et Van. 5 parts, car Mulberry young 6 parts, Radix desmodiik microphylli 6 parts, Radix Astragali 7 parts, 5 parts of groups of Endothelium corneum Anseris domestica Become.
After 5 days, experimental result is as follows:
Blank group Matched group Experiment A group Experiment B group Experiment C group Experiment D group Experiment E group Experiment F group Experiment G group
Cure (tail) 0 44 44 45 47 46 49 48 49
Take a turn for the better (tail) 0 3 6 5 3 4 1 2 1
Dead (tail) 17 3 0 0 0 0 0 0 0
Result is added up:
Blank group: dead 17 tail, separately the white point on other 33 tail healths increases；Mortality rate 34%.
Matched group: cure rate 88%, improvement rate 6%, mortality rate 6%.
Experiment A group: cure rate 88%, improvement rate 12%, mortality rate 0.
Experiment B group: cure rate 90%, improvement rate 10%, mortality rate 0.
Experiment C group: cure rate 94%, improvement rate 6%, mortality rate 0.
Experiment D group: cure rate 92%, improvement rate 8%, mortality rate 0.
Experiment E group: cure rate 98%, improvement rate 2%, mortality rate 0.
Experiment F group: cure rate 96%, improvement rate 4%, mortality rate 0.
Experiment G group: cure rate 98%, improvement rate 2%, mortality rate 0.
Experiment two: after drug withdrawal three days, matched group, experiment A group, experiment B group, experiment C group, experiment D group, experiment E group, experiment F group and experiment G group are reprocessed once according to the method for experiment one.
After process terminates, this pincers fish suffering from ichthyophthiriasis of 8 groups is all cured.After one month, observe this 8 groups of ichthyophthiriasis recurrences Situation, finds that matched group has 5 fish ichthyophthiriasis recurrences, and experiment A group, to experiment G group, does not find ichthyophthiriasis.
Interpretation of result: the result of experiment one shows that the effect of the compositions healing pincers fish ichthyophthiriasis of the present invention is better than existing skill Art；The result of experiment two shows that prior art treats ichthyophthiriasis, and treatment is not thorough, easily recurs；The compositions using the present invention is controlled Treat ichthyophthiriasis, thorough treatment, be difficult to recurrence.
Above-described is only embodiments of the invention, and in scheme, the known general knowledge such as using method and characteristic is not made at this Too much describe.It should be pointed out that, for a person skilled in the art, under the premise of not departing from the present invention, it is also possible to make Some improvement, these also should be considered as protection scope of the present invention, and these are all without affecting effect and the patent that the present invention implements Practicality.The protection domain that this application claims should be as the criterion with the content of its claim, the specific embodiment party in description Formulas etc. record the content that may be used for explaining claim.

Claims (4)

1. the compositions treating pincers fish ichthyophthiriasis, it is characterised in that: according to mass fraction meter, including Caulis fici pumilae (Fructus Fici Pumilae) juice 10-14 part, Kalopanax septemlobum tree 6-8 part, Paederus densipennis Bernh. 5-7 part, Herba Setariae viridis 2-4 part.
A kind of compositions treating pincers fish ichthyophthiriasis the most according to claim 1, it is characterised in that: according to mass fraction Meter, also comprises Folium Callicarpae Formosanae 6-8 part, Chrysosplenium Hydrocotylifolium Levl. Et Van. 4-6 part.
A kind of compositions treating pincers fish ichthyophthiriasis the most according to claim 2, it is characterised in that: according to mass fraction Meter, also includes car Mulberry son's 5-7 part, Radix desmodiik microphylli 5-7 part.
A kind of compositions treating pincers fish ichthyophthiriasis the most according to claim 3, it is characterised in that: according to mass fraction Meter, is by 13 parts of Caulis fici pumilae (Fructus Fici Pumilae) juice, 7 parts of Kalopanax septemlobum tree, Paederus densipennis Bernh. 6 parts, Herba Setariae viridis 3 parts, Folium Callicarpae Formosanae 7 parts, Chrysosplenium Hydrocotylifolium Levl. Et Van. 5 parts, Che Sang Young 6 parts, Radix desmodiik microphylli 6 parts, Radix Astragali 7 parts, Endothelium corneum Anseris domestica 5 parts composition.
CN201610657334.5A 2016-08-11 2016-08-11 A kind of compositions treating pincers fish ichthyophthiriasis Pending CN106138822A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105169318A (en) * 2015-09-15 2015-12-23 青岛海之源智能技术有限公司 Traditional Chinese medicinal herbal preparation for treating ichthyophthiriasis of osteoglossum bicirrhosum
CN105341534A (en) * 2015-11-30 2016-02-24 青岛海之源智能技术有限公司 Feed additive for preventing white-spot disease of parrot fishes and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105169318A (en) * 2015-09-15 2015-12-23 青岛海之源智能技术有限公司 Traditional Chinese medicinal herbal preparation for treating ichthyophthiriasis of osteoglossum bicirrhosum
CN105341534A (en) * 2015-11-30 2016-02-24 青岛海之源智能技术有限公司 Feed additive for preventing white-spot disease of parrot fishes and preparation method thereof

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