CN105194627A - Preparation for treating gill-rot disease of lateolabrax japonicus and preparation method of preparation - Google Patents
Preparation for treating gill-rot disease of lateolabrax japonicus and preparation method of preparation Download PDFInfo
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Abstract
The invention relates to a preparation for treating a gill-rot disease of lateolabrax japonicus and further relates to a preparation method of the preparation for treating the gill-rot disease of lateolabrax japonicus. The preparation for treating the gill-rot disease of lateolabrax japonicus comprises components in parts by mass as follows: 24-34 parts of watermelon juice, 20-26 parts of Chinese honey locust juice, 20-26 parts of bitter gourd juice, 19-25 parts of dandelion, 19-25 parts of blackend swallowwort roots, 19-25 parts of Chinese pulsatilla roots, 17-24 parts of drug sweetflag rhizomes, 16-24 parts of morning glory, 17-23 parts of astragalus sinicus, 15-24 parts of eucommia barks, 16-23 parts of heterophylly falsestarwort roots, 13-23 parts of agrimony, 13-23 parts of moutan barks, 13-22 parts of philippine violet herb, 14-22 parts of shrubalthea barks, 12-21 parts of fresh ginger, 12-19 parts of blackberrykiky rhizomes, 12-18 parts of heartleaf houttuynia herb, 11-18 parts of lotus nuts and the like. The Chinese herbal medicine preparation has a high cure rate for the gill-rot disease of lateolabrax japonicus.
Description
Technical field
The invention belongs to technical field of aquaculture, particularly relate to a kind of preparation for the treatment of Lateolabrax japonicus gill rot; The invention still further relates to a kind of preparation method of preparation of above-mentioned treatment Lateolabrax japonicus gill rot.
Background technology
(it is parallel that side line carries on the back edge with body to Lateolabrax japonicus completely, and body is by tiny ctenoid scale, and cortex is coarse, scale difficult drop-off, and body dorsal part is cinerous, veutro canescence for Lateolabraxjaponicus) Shu Yu Sushi section, body extension and flat-sided.Lateolabrax japonicus is distributed in west of pacific ocean, and China coast all produces, and the Huanghai Sea, the Bohai Sea are more, and the main place of production is the ground such as Qingdao, stone island, Qinhuangdao and Zhoushan Islands.Lateolabrax japonicus is good breed variety, and Lateolabrax japonicus grazing eclipse is strong, and available minced fish or chilled small fish, wild fishes cube meat are fed, and can to throw something and feed compound feed through domestication.Lateolabrax japonicus meat is delicate, delicate fragrance, does not have fishy smell, and meat is garlic clove shape, has the effect of invigorating the liver and kidney, strengthening the spleen stomach, preventing phlegm from forming and stopping coughing, has good benefiting action to Liver and kidney weakling, also can control the disease such as frequent fetal movement, puerperal lactation deficiency.Ready-to-be mother and postpartum women had not only been mended body, and but also can not caused overnutrition and cause fat after eating, be that body-building is enriched blood, the good merchantable brand of invigorating the spleen and benefiting QI and beneficial body Ankang.
Lateolabrax japonicus bacterial gill rot disease is the modal a kind of disease of Lateolabrax japonicus, and the generation of this disease is main relevant with the parasite parasitized on the gill, first causes the gill to damage by parasite, then causes bacillary secondary infection.In slow death, sick fish mostly is next year fish, and if do not noted prevention, cumulative mortality can reach 40%.Its symptom is: Lateolabrax japonicus peels off after infecting and solely swims, slow in action, bradykinesia, body colour is turned black, and head is especially pitch-black, dyspnea, loss of appetite, the dermathemia inflammation of the visible gill cover inner surface of naked eyes, time serious, mid portion normal rotten to the corn one-tenth one circle or irregular transparent fenestella greatly, gill mucus increases, gill filament swelling, end are rotted, and cartilage exposes, and the sick fish be in a bad way still has floating head phenomenon after changing clear water.Bacterial gill rot disease is popular in high temperature season usually, can cause large quantities of death of Lateolabrax japonicus.Bacterial gill rot disease is caused by Cytophaga Columnaris, and carry disease germs fish and the water that carries disease germs are the sources of infection of this disease, and in this sick epidemic season, sick fish constantly scatters pathogen in water, and fish body contacts with pathogen, and especially gill portion is impaired especially easily causes infection afterwards.Easily this disease is there is in the environment that, water quality excessive at stocking density is poor.Bacterial gill rot disease is generally in water temperature about 20 DEG C beginning, and general morbidity in 5 ~ July, when water temperature drop reduces gradually to 15 DEG C of seasonal disease fishes.Between period of disease, the higher lethal time of raising water temperature is shorter.But, current treatment Lateolabrax japonicus bacterial gill rot disease conventional means is with the conventional chemical medicine such as furazolidone, erythromycin or antibiotic medicine sterilization, its shortcoming is that therapeutic effect is not good, toxicity is larger, toxic residual in Lateolabrax japonicus body, not only easily can pollute, affect the sustainable health development of culture fishery on environment, and also can affect the healthy of people after ingesting.
Summary of the invention
An object of the present invention is to provide a kind of preparation for the treatment of Lateolabrax japonicus gill rot, and its raw material components is green pure natural material, and high to Lateolabrax japonicus gill rot cure rate, the Health restoration of Lateolabrax japonicus is fast.
In order to solve the problems of the technologies described above, the present invention by the following technical solutions, a kind of preparation for the treatment of Lateolabrax japonicus gill rot, be made up of each component of following masses number: Citrullus vulgaris juice 24-34 part, Fructus Gleditsia juice 20-26 part, Fructus Momordicae charantiae juice 20-26 part, Herba Taraxaci 19-25 part, Radix Cynanchi Atrati 19-25 part, Radix Pulsatillae 19-25 part, Rhizoma Acori Graminei 17-24 part, morning glory 16-24 part, Herba Astragali Melilotoidis (Herba Astragali Sinici) 17-23 part, Cortex Eucommiae 15-24 part, Radix Pseudostellariae 16-23 part, Serpentis pimple 13-23 part, Cortex Moutan 13-23 part, Herba Violae 13-22 part, Cortex Hibisci 14-22 part, Rhizoma Zingiberis Recens 12-21 part, Rhizoma Belamcandae 12-19 part, Herba Houttuyniae 12-18 part, Plumula Nelumbinis 11-18 part, Radix Rubiae 9-16 part, Herba Portulacae 9-15 part, Herba Chenopodii 8-16 part, bamboo salt 8-14 part, rice vinegar 6-12 part.
Preferably, the preparation of described treatment Lateolabrax japonicus gill rot, be made up of each component of following masses number: Citrullus vulgaris juice 28-30 part, Fructus Gleditsia juice 22-24 part, Fructus Momordicae charantiae juice 22-24 part, Herba Taraxaci 21-23 part, Radix Cynanchi Atrati 21-23 part, Radix Pulsatillae 20-23 part, Rhizoma Acori Graminei 19-22 part, morning glory 19-21 part, Herba Astragali Melilotoidis (Herba Astragali Sinici) 19-21 part, Cortex Eucommiae 18-21 part, Radix Pseudostellariae 18-20 part, Serpentis pimple 17-19 part, Cortex Moutan 17-19 part, Herba Violae 16-18 part, Cortex Hibisci 17-19 part, Rhizoma Zingiberis Recens 15-18 part, Rhizoma Belamcandae 15-17 part, Herba Houttuyniae 14-16 part, Plumula Nelumbinis 14-15 part, Radix Rubiae 11-14 part, Herba Portulacae 11-13 part, Herba Chenopodii 11-13 part, bamboo salt 10-12 part, rice vinegar 8-10 part.
Preferably; the preparation of described treatment Lateolabrax japonicus gill rot, is made up of each component of following masses number: Citrullus vulgaris juice 29 parts, Fructus Gleditsia juice 23 parts, Fructus Momordicae charantiae juice 23 parts, Herba Taraxaci 22 parts, Radix Cynanchi Atrati 22 parts, the Radix Pulsatillae 21 parts, Rhizoma Acori Graminei 21 parts, 20 parts, morning glory, Herba Astragali Melilotoidis (Herba Astragali Sinici) 20 parts, the Cortex Eucommiae 20 parts, Radix Pseudostellariae 19 parts, Serpentis pimple 18 parts, Cortex Moutan 18 parts, Herba Violae 17 parts, Cortex Hibisci 18 parts, 17 parts, Rhizoma Zingiberis Recens, Rhizoma Belamcandae 16 parts, Herba Houttuyniae 15 parts, Plumula Nelumbinis 15 parts, 13 parts, Radix Rubiae, Herba Portulacae 12 parts, Herba Chenopodii 12 parts, bamboo salt 11 parts, rice vinegar 9 parts.
Another object of the present invention is to provide a kind of preparation method of preparation of above-mentioned treatment Lateolabrax japonicus gill rot, and the preparation method of the preparation of this treatment Lateolabrax japonicus gill rot comprises the following steps:
(1) take Herba Taraxaci, Radix Cynanchi Atrati, the Radix Pulsatillae and Rhizoma Acori Graminei respectively according to proportioning, gross weight is designated as 1 part, adds 12 parts of purified water, and 70-80 DEG C is soaked 1h, obtain soak;
(2) boil 2h after the soak that step (1) obtains being heated to boiling, be separated and take out fried liquid, continue the purified water adding 6 parts in medical material, continue to boil 1h after being heated to boiling, merge twice fried liquid and be extracting solution;
(3) morning glory, Herba Astragali Melilotoidis (Herba Astragali Sinici), the Cortex Eucommiae, Radix Pseudostellariae, Serpentis pimple, Cortex Moutan, Herba Violae, Cortex Hibisci, Rhizoma Zingiberis Recens, Rhizoma Belamcandae, Herba Houttuyniae, Plumula Nelumbinis, Radix Rubiae, Herba Portulacae, Herba Chenopodii is taken respectively according to proportioning, load ball mill grinding 2h, cross 80 mesh sieves, obtain grounds travel;
(4) grounds travel that extracting solution step (2) obtained and step (3) obtain is positioned in the extraction kettle in supercritical extraction instrument, carbon dioxide is utilized to extract as medium, extraction kettle pressure is 40Mpa, extraction temperature is 45 DEG C, separator pressure 12Mpa, separator temperature is 70 DEG C, extracts 2 hours, is extracted liquid;
(5) step Citrullus vulgaris juice, Fructus Gleditsia juice, Fructus Momordicae charantiae juice, bamboo salt and rice vinegar is taken respectively according to proportioning, load weighted Citrullus vulgaris juice, Fructus Gleditsia juice, Fructus Momordicae charantiae juice, bamboo salt and the rice vinegar extract with step (4) gained is mixed homogeneously, obtains object.
The preparation method of described Citrullus vulgaris juice is: ground or put into juice extractor by flesh of Pulp Citrulli and squeeze the juice, gained juice is Citrullus vulgaris juice.
The preparation method of described Fructus Gleditsia juice is: ground or put into juice extractor by Fructus Gleditsia and squeeze the juice, gained juice is Fructus Gleditsia juice.
The preparation method of described Fructus Momordicae charantiae juice is: ground or put into juice extractor by Fructus Momordicae charantiae and squeeze the juice, gained juice is Fructus Momordicae charantiae juice.
The using method of the present invention when treating Lateolabrax japonicus gill rot is as follows: water per ton pours the preparation of the present invention of 30-40ml into, within every 12 hours, changes water once, adds preparation of the present invention after changing water by same ratio, uses continuously until recovery from illness.
The using method of the present invention when preventing Lateolabrax japonicus gill rot is as follows: water per ton pours the preparation of the present invention of 20-25ml into, changes water once after 24 hours, adds preparation of the present invention after changing water by same ratio, after using 2 days continuously, stops 1 day; A circulation 5-8 cycle like this.
Each component effect of the present invention is resolved as follows:
Citrullus vulgaris juice has the effects such as antiinflammatory, diuresis, elimination edema, can improve various inflammation, improve white hair, sore waist and aching in the waist and the back, good to nephritis recovery effects especially, can supplement needed by human fructose, and opposing is old and feeble, prevents sclerosis of blood vessels, improves allergic constitution.Fructus Gleditsia has the effect of parasite killing, removing toxic substances: saponin element contained in Fructus Gleditsia is triterpene class and oligosaccharide, has antiinflammatory, antiulcer, disease-resistant change effect, also has anticancer and improves the effects such as acquired immune deficiency syndrome (AIDS) immunity.Fructus Momordicae charantiae is Cucurbitaceae Momordica plant, and its bitter cold is nontoxic, pathogenic heat can be fallen, separate tired, the improving eyesight that can clear away heart-fire, QI invigorating tonifying YANG.Herba Taraxaci energy bactericidal antiphlogistic, heat-clearing and toxic substances removing, diuresis eliminating stagnation.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Radix Cynanchi Atrati another name common vetch grass, know that micro-old, old melon gourd dipper root, mountain cigarette root, hundred swing grass, Baima common vetch, Rhizoma Cynanchi Stauntonii, Radix Tylophorae arenicolae, the upright perennial herb of asclepiadaceae, Cynanchum, root hair shape, has fragrance, has except fidgets due to deficiency, heat clearing away are loose swollen, the effect of granulation promoting pain relieving, fidgets due to deficiency vomiting after can managing property; dribbling urination, nephritis, urinary tract infection; edema, bronchitis and rheumatic lumbago and scelalgia etc.The Radix Pulsatillae can treat the bleedings such as hemorrhoid, can control toxic-heat and blood stasis, pyrexial malaria cold and heat, epistaxis, internal hemorrhoid with bleeding, and the research such as Lan Jiyu finds that Radix Pulsatillae decoct is better to the effect killing Entamoeba histolytica; Cao Jinghua etc. record Radix Pulsatillae Aqueous extracts with K-B disk diffusion method and have obvious inhibitory action to staphylococcus aureus, bacillus pyocyaneus, anthrax bacillus, Bacillus typhi, alpha streptococcus, group B streptococcus.Rhizoma Acori Graminei can be dispelled epidemic disease Fructus Alpiniae Oxyphyllae, damp eliminating removing toxic substances, building body, combustion Rhizoma Acori Graminei, Folium Artemisiae Argyi, anophelifuge deinsectization, after 500 grams, Rhizoma Acori Graminei rhizome is mashed, add water 1-1.5 kilogram of infusion two hours, the stock solution of gained, is watered 3-6 kilogram after filtration, can effectively prevent and treat the insect pests such as planthopper, rice leafhopper, rice green caterpillar, aphid, red spider.Morning glory has removing water retention by purgation diuresis, effect by expectorant, detumescence, parasite killing anthelmintic, cures mainly the diseases such as limds edema, oedema due to nephritis, cirrhotic ascites, constipation, abdominal pain due to worm stagnation.Herba Astragali Melilotoidis (Herba Astragali Sinici) cures mainly removing blood stasis, hemostasia and promoting granulation, and profit can support the five internal organs, improve visual and auditory acuity, hot blast of dispelling, makes us spry and light, and food is not minded for a long time, mends people, can stop hot malaria, flat stomach of invigorating blood circulation.The Cortex Eucommiae has invigorating the liver and kidney, control spinal column ache, foot and knee flaccidity; dribbling urination; uncontrolled urination is itched, hypertension, antiabortive effect, the Cortex Eucommiae has regulating action in various degree to immune system, hormonal system, central nervous system, blood circulation and urinary system; the excited Pituitary Adrenalcortical system of Cortex Eucommiae energy, adrenal cortex reinforcing function.Radix Pseudostellariae is the dried root of pinkwort Radix Ginseng, has replenishing QI to invigorate the spleen, effect of promoting the production of body fluid for nourishing the lung, is usually used in treating insufficiency of the spleen body tired, inappetence, weak after being ill, and deficiency of both vital energy and Yin, spontaneous perspiration day is thirsty, dryness of the lung dry cough.Serpentis pimple energy anti-inflammtory anti-dysentery, menstruction regulating and pain relieving, hemostasis, can be used for enteritis, bacillary dysentery, menoxenia, dysmenorrhea, rheumatalgia, fracture, traumatic injury swelling and pain due to blood stasis.Cortex Moutan is the dry root bark of ranunculaceae peony, bitter in the mouth, pungent, and cold nature, has the effects such as clearing away heat and cooling blood, activating blood circulation to dissipate blood stasis, reducing the asthenic fever, can be used for the treatment of to fall and flutter the pain of injury, carbuncle sore tumefacting virus.Herba Violae taste bitter, acrid, cold, GUIXIN, lung meridian, have heat-clearing and toxic substances removing, and removing heat from blood is subsided a swelling, and the effect of clearing away heat-damp and promoting diuresis, cures mainly furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.Cortex Hibisci energy clearing away heat-damp and promoting diuresis, killing parasites for relieving itching, can be used for treating dysentery, leucorrhea; Eczema scrotum tinea corporis is controlled in external, tinea pedis.Rhizoma Zingiberis Recens has bactericidal effect, and can strengthen digestion power.Rhizoma Belamcandae is perennial herb, bitter in the mouth, cold in nature, micro-poison, and energy heat-clearing and toxic substances removing, eliminating stagnation antiinflammatory, reducing swelling and alleviating pain, relieving cough and resolving phlegm, be used for the treatment of tonsillitis and lumbago.Herba Houttuyniae has heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, the effect of inducing diuresis for treating stranguria syndrome.Plumula Nelumbinis and Plumula Nelumbinis, have clearing away heart-fire, suppressing the hyperactive liver fire, hemostasis, effect of controlling nocturnal emission with astringent drugs.Radix Rubiae bitter in the mouth, cold in nature, return Liver Channel, have cooling blood for hemostasis, blood stasis dispelling, the effect of stimulating the menstrual flow, cure mainly heat in blood and tell nosebleed, metrostaxis, blood stasis amenorrhea, traumatic injury, rheumatic arthralgia, because Radix Rubiae has the effect of promoting blood circulation to restore menstrual flow, be commonly used to clinically treat rheumatic arthralgia.Herba Portulacae is Portulacaceae annual herb plant, herb hyoscine, has clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, antiinflammatory, quenches the thirst, diuresis.Herba Chenopodii another name red pool indigo plant, sky Herba mesonae chinensis, Herba rutae, ancylostome grass, lousewort etc., Herba Chenopodii can expelling wind and removing dampness, and parasite killing, antipruritic, can be used for ascariasis, ancylostomiasis, enterobiasis, skin eczema is controlled in external, pruritus, and kills maggot.Bamboo salt is evaporated brine day to load in triennial QINGZHU, and two ends are sealed with natural loess, take pinaster as fuel, the material extract after 1000 DEG C ~ 1500 DEG C high-temperature calcinations, has antibacterial, antiinflammatory, toxopexic effect.Rice vinegar can sterilize, antibacterial, detoxify, help digestion, relieving restlessness of calming the nerves.
In preparation method, crude drug purified water soaking a period of time, medical material deliquescing, cell expansion, effective ingredient is easily fried, and medical material contains starch, protein, after soaking, prevent when decocting, the starch gelatinization on medical material surface, protein coagulating, the capillary channel on blocking medical material surface, make the moisture when decocting enter not go, effective ingredient is not easily fried, affects curative effect of medication; Decoction can change the irritation effect of medicine, relatively mildly acts on Lateolabrax japonicus, promotes that Lateolabrax japonicus is to the absorption of medicine; Grinding makes the starch in medical material, protein is separated out more fully at subsequent step; Supercritical extraction, immersion, concentration step retain the effective ingredient of each component in the present invention to greatest extent.
The preparation for the treatment of Lateolabrax japonicus gill rot of the present invention is the mechanism of action according to gill rot, the suitable component of selection, and is organically combined, and has significant cooperative synergism effect, plays the function of each component to greatest extent.The component of the preparation for the treatment of Lateolabrax japonicus gill rot of the present invention is environmental protection raw material, nontoxic to environment, do not use chemical drugs or antibiotic, the healthy of people can not be affected after edible Lateolabrax japonicus of having cured, and preparation of the present invention is good to the curative effect of Lateolabrax japonicus gill rot, cure rate is high, raise the nose above water to breathe after medication 2-4 days phenomenon disappear, Lateolabrax japonicus ingestion frequency improve.In addition, the present invention uses safer, little to Lateolabrax japonicus damage, and after using the preparation for the treatment of Lateolabrax japonicus bacterial enteritis of the present invention, Lateolabrax japonicus Health restoration is fast, medication 5-9 days, and Lateolabrax japonicus can recover normal activity, and idle fund is strong and vigorous, ingests completely normal.In addition, the preparation for the treatment of Lateolabrax japonicus gill rot of the present invention can not only be high to gill rot cure rate when Lateolabrax japonicus gill rot is sent out, and effectively can prevent the generation of Lateolabrax japonicus gill rot.
Compared with prior art, the invention has the beneficial effects as follows:
(1) Citrullus vulgaris juice is monarch drug, and Citrullus vulgaris juice has the effects such as antiinflammatory, diuresis, elimination edema, can improve various inflammation, improve white hair, sore waist and aching in the waist and the back, good to nephritis recovery effects especially, needed by human fructose can be supplemented, opposing is old and feeble, prevents sclerosis of blood vessels, improves allergic constitution.
Fructus Gleditsia has the effect of parasite killing, removing toxic substances: saponin element contained in Fructus Gleditsia is triterpene class and oligosaccharide, has antiinflammatory, antiulcer, disease-resistant change effect, also has anticancer and improves the effects such as acquired immune deficiency syndrome (AIDS) immunity.Fructus Momordicae charantiae is Cucurbitaceae Momordica plant, and its bitter cold is nontoxic, pathogenic heat can be fallen, separate tired, the improving eyesight that can clear away heart-fire, QI invigorating tonifying YANG.Herba Taraxaci energy bactericidal antiphlogistic, heat-clearing and toxic substances removing, diuresis eliminating stagnation.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Radix Cynanchi Atrati another name common vetch grass, know that micro-old, old melon gourd dipper root, mountain cigarette root, hundred swing grass, Baima common vetch, Rhizoma Cynanchi Stauntonii, Radix Tylophorae arenicolae, the upright perennial herb of asclepiadaceae, Cynanchum, root hair shape, has fragrance, has except fidgets due to deficiency, heat clearing away are loose swollen, the effect of granulation promoting pain relieving, fidgets due to deficiency vomiting after can managing property; dribbling urination, nephritis, urinary tract infection; edema, bronchitis and rheumatic lumbago and scelalgia etc.The Radix Pulsatillae can treat the bleedings such as hemorrhoid, can control toxic-heat and blood stasis, pyrexial malaria cold and heat, epistaxis, internal hemorrhoid with bleeding, and the research such as Lan Jiyu finds that Radix Pulsatillae decoct is better to the effect killing Entamoeba histolytica; Cao Jinghua etc. record Radix Pulsatillae Aqueous extracts with K-B disk diffusion method and have obvious inhibitory action to staphylococcus aureus, bacillus pyocyaneus, anthrax bacillus, Bacillus typhi, alpha streptococcus, group B streptococcus.Rhizoma Acori Graminei can be dispelled epidemic disease Fructus Alpiniae Oxyphyllae, damp eliminating removing toxic substances, building body, combustion Rhizoma Acori Graminei, Folium Artemisiae Argyi, anophelifuge deinsectization, after 500 grams, Rhizoma Acori Graminei rhizome is mashed, add water 1-1.5 kilogram of infusion two hours, the stock solution of gained, is watered 3-6 kilogram after filtration, can effectively prevent and treat the insect pests such as planthopper, rice leafhopper, rice green caterpillar, aphid, red spider.Fructus Gleditsia juice, Fructus Momordicae charantiae juice, Herba Taraxaci, Radix Cynanchi Atrati, the Radix Pulsatillae and Rhizoma Acori Graminei are ministerial drug.
Morning glory has removing water retention by purgation diuresis, effect by expectorant, detumescence, parasite killing anthelmintic, cures mainly the diseases such as limds edema, oedema due to nephritis, cirrhotic ascites, constipation, abdominal pain due to worm stagnation.Herba Astragali Melilotoidis (Herba Astragali Sinici) cures mainly removing blood stasis, hemostasia and promoting granulation, and profit can support the five internal organs, improve visual and auditory acuity, hot blast of dispelling, makes us spry and light, and food is not minded for a long time, mends people, can stop hot malaria, flat stomach of invigorating blood circulation.The Cortex Eucommiae has invigorating the liver and kidney, control spinal column ache, foot and knee flaccidity; dribbling urination; uncontrolled urination is itched, hypertension, antiabortive effect, the Cortex Eucommiae has regulating action in various degree to immune system, hormonal system, central nervous system, blood circulation and urinary system; the excited Pituitary Adrenalcortical system of Cortex Eucommiae energy, adrenal cortex reinforcing function.Radix Pseudostellariae is the dried root of pinkwort Radix Ginseng, has replenishing QI to invigorate the spleen, effect of promoting the production of body fluid for nourishing the lung, is usually used in treating insufficiency of the spleen body tired, inappetence, weak after being ill, and deficiency of both vital energy and Yin, spontaneous perspiration day is thirsty, dryness of the lung dry cough.Serpentis pimple energy anti-inflammtory anti-dysentery, menstruction regulating and pain relieving, hemostasis, can be used for enteritis, bacillary dysentery, menoxenia, dysmenorrhea, rheumatalgia, fracture, traumatic injury swelling and pain due to blood stasis.Cortex Moutan is the dry root bark of ranunculaceae peony, bitter in the mouth, pungent, and cold nature, has the effects such as clearing away heat and cooling blood, activating blood circulation to dissipate blood stasis, reducing the asthenic fever, can be used for the treatment of to fall and flutter the pain of injury, carbuncle sore tumefacting virus.Herba Violae taste bitter, acrid, cold, GUIXIN, lung meridian, have heat-clearing and toxic substances removing, and removing heat from blood is subsided a swelling, and the effect of clearing away heat-damp and promoting diuresis, cures mainly furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.Cortex Hibisci energy clearing away heat-damp and promoting diuresis, killing parasites for relieving itching, can be used for treating dysentery, leucorrhea; Eczema scrotum tinea corporis is controlled in external, tinea pedis.Rhizoma Zingiberis Recens has bactericidal effect, and can strengthen digestion power.Rhizoma Belamcandae is perennial herb, bitter in the mouth, cold in nature, micro-poison, and energy heat-clearing and toxic substances removing, eliminating stagnation antiinflammatory, reducing swelling and alleviating pain, relieving cough and resolving phlegm, be used for the treatment of tonsillitis and lumbago.Herba Houttuyniae has heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, the effect of inducing diuresis for treating stranguria syndrome.Morning glory, Herba Astragali Melilotoidis (Herba Astragali Sinici), the Cortex Eucommiae, Radix Pseudostellariae, Serpentis pimple, Cortex Moutan, Herba Violae, Cortex Hibisci, Rhizoma Zingiberis Recens, Rhizoma Belamcandae and Herba Houttuyniae are adjuvant drug.
Plumula Nelumbinis and Plumula Nelumbinis, have clearing away heart-fire, suppressing the hyperactive liver fire, hemostasis, effect of controlling nocturnal emission with astringent drugs.Radix Rubiae bitter in the mouth, cold in nature, return Liver Channel, have cooling blood for hemostasis, blood stasis dispelling, the effect of stimulating the menstrual flow, cure mainly heat in blood and tell nosebleed, metrostaxis, blood stasis amenorrhea, traumatic injury, rheumatic arthralgia, because Radix Rubiae has the effect of promoting blood circulation to restore menstrual flow, be commonly used to clinically treat rheumatic arthralgia.Herba Portulacae is Portulacaceae annual herb plant, herb hyoscine, has clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, antiinflammatory, quenches the thirst, diuresis.Herba Chenopodii another name red pool indigo plant, sky Herba mesonae chinensis, Herba rutae, ancylostome grass, lousewort etc., Herba Chenopodii can expelling wind and removing dampness, and parasite killing, antipruritic, can be used for ascariasis, ancylostomiasis, enterobiasis, skin eczema is controlled in external, pruritus, and kills maggot.Bamboo salt is evaporated brine day to load in triennial QINGZHU, and two ends are sealed with natural loess, take pinaster as fuel, the material extract after 1000 DEG C ~ 1500 DEG C high-temperature calcinations, has antibacterial, antiinflammatory, toxopexic effect.Rice vinegar can sterilize, antibacterial, detoxify, help digestion, relieving restlessness of calming the nerves.Plumula Nelumbinis, Radix Rubiae, Herba Portulacae, Herba Chenopodii, bamboo salt and rice vinegar are for making medicine.
(2) preparation for the treatment of Lateolabrax japonicus gill rot of the present invention, is the raw material components selected according to the mechanism of action of gill rot, and is organically combined, have significant cooperative synergism effect, play the function of each component to greatest extent.
(3) pathogen of preparation to Lateolabrax japonicus gill rot for the treatment of Lateolabrax japonicus gill rot of the present invention has good inhibition.
(4) component of the preparation for the treatment of Lateolabrax japonicus gill rot of the present invention is environmental protection raw material, nontoxic to environment, without chemical drugs or antibiotic, the healthy of people can not be affected after edible Lateolabrax japonicus of having cured, and the preparation for the treatment of Lateolabrax japonicus gill rot of the present invention is very little to Lateolabrax japonicus damage, after using the preparation for the treatment of Lateolabrax japonicus gill rot of the present invention, Lateolabrax japonicus Health restoration is fast.
(5) in preparation method, crude drug purified water soaking a period of time, medical material deliquescing, cell expansion, effective ingredient is easily fried, and medical material contains starch, protein, after soaking, prevent when decocting, the starch gelatinization on medical material surface, protein coagulating, the capillary channel on blocking medical material surface, make the moisture when decocting enter not go, effective ingredient is not easily fried, affects curative effect of medication; Decoction can change the irritation effect of medicine, relatively mildly acts on Lateolabrax japonicus, promotes that Lateolabrax japonicus is to the absorption of medicine; Grinding makes the starch in medical material, protein is separated out more fully at subsequent step; Supercritical extraction, immersion, concentration step retain the effective ingredient in Chinese medicine of the present invention to greatest extent.
Detailed description of the invention
Following embodiment is convenient to understand the present invention better, but does not limit the present invention.Experimental technique in following embodiment, if no special instructions, is conventional method.
Embodiment 1
In the present invention's first detailed description of the invention, feed ingredient and preparation method thereof is as follows:
Treat a preparation for Lateolabrax japonicus gill rot, be made up of each component of following masses number: Citrullus vulgaris juice 34 parts, Fructus Gleditsia juice 26 parts, Fructus Momordicae charantiae juice 26 parts, Herba Taraxaci 25 parts, Radix Cynanchi Atrati 25 parts, the Radix Pulsatillae 25 parts, Rhizoma Acori Graminei 24 parts, 24 parts, morning glory, Herba Astragali Melilotoidis (Herba Astragali Sinici) 23 parts, the Cortex Eucommiae 24 parts, Radix Pseudostellariae 23 parts, Serpentis pimple 23 parts, Cortex Moutan 23 parts, Herba Violae 22 parts, Cortex Hibisci 22 parts, 21 parts, Rhizoma Zingiberis Recens, Rhizoma Belamcandae 19 parts, Herba Houttuyniae 18 parts, Plumula Nelumbinis 18 parts, 16 parts, Radix Rubiae, Herba Portulacae 15 parts, Herba Chenopodii 16 parts, bamboo salt 14 parts, rice vinegar 12 parts.
The preparation method of the preparation of above-mentioned treatment Lateolabrax japonicus gill rot comprises the following steps:
(1) take Herba Taraxaci, Radix Cynanchi Atrati, the Radix Pulsatillae and Rhizoma Acori Graminei respectively according to proportioning, gross weight is designated as 1 part, adds 12 parts of purified water, and 70-80 DEG C is soaked 1h, obtain soak;
(2) boil 2h after the soak that step (1) obtains being heated to boiling, be separated and take out fried liquid, continue the purified water adding 6 parts in medical material, continue to boil 1h after being heated to boiling, merge twice fried liquid and be extracting solution;
(3) morning glory, Herba Astragali Melilotoidis (Herba Astragali Sinici), the Cortex Eucommiae, Radix Pseudostellariae, Serpentis pimple, Cortex Moutan, Herba Violae, Cortex Hibisci, Rhizoma Zingiberis Recens, Rhizoma Belamcandae, Herba Houttuyniae, Plumula Nelumbinis, Radix Rubiae, Herba Portulacae, Herba Chenopodii is taken respectively according to proportioning, load ball mill grinding 2h, cross 80 mesh sieves, obtain grounds travel;
(4) grounds travel that extracting solution step (2) obtained and step (3) obtain is positioned in the extraction kettle in supercritical extraction instrument, carbon dioxide is utilized to extract as medium, extraction kettle pressure is 40Mpa, extraction temperature is 45 DEG C, separator pressure 12Mpa, separator temperature is 70 DEG C, extracts 2 hours, is extracted liquid;
(5) step Citrullus vulgaris juice, Fructus Gleditsia juice, Fructus Momordicae charantiae juice, bamboo salt and rice vinegar is taken respectively according to proportioning, load weighted Citrullus vulgaris juice, Fructus Gleditsia juice, Fructus Momordicae charantiae juice, bamboo salt and the rice vinegar extract with step (4) gained is mixed homogeneously, obtains object.
The preparation method of described Citrullus vulgaris juice is: ground or put into juice extractor by flesh of Pulp Citrulli and squeeze the juice, gained juice is Citrullus vulgaris juice.
The preparation method of described Fructus Gleditsia juice is: ground or put into juice extractor by Fructus Gleditsia and squeeze the juice, gained juice is Fructus Gleditsia juice.
The preparation method of described Fructus Momordicae charantiae juice is: ground or put into juice extractor by Fructus Momordicae charantiae and squeeze the juice, gained juice is Fructus Momordicae charantiae juice.
Embodiment 2
In the present invention's second detailed description of the invention, feed ingredient and preparation method thereof is as follows:
Treat a preparation for Lateolabrax japonicus gill rot, be made up of each component of following masses number: Citrullus vulgaris juice 32 parts, Fructus Gleditsia juice 24 parts, Fructus Momordicae charantiae juice 24 parts, Herba Taraxaci 23 parts, Radix Cynanchi Atrati 23 parts, the Radix Pulsatillae 22 parts, Rhizoma Acori Graminei 22 parts, 21 parts, morning glory, Herba Astragali Melilotoidis (Herba Astragali Sinici) 21 parts, the Cortex Eucommiae 21 parts, Radix Pseudostellariae 20 parts, Serpentis pimple 20 parts, Cortex Moutan 20 parts, Herba Violae 18 parts, Cortex Hibisci 19 parts, 18 parts, Rhizoma Zingiberis Recens, Rhizoma Belamcandae 17 parts, Herba Houttuyniae 16 parts, Plumula Nelumbinis 15 parts, 14 parts, Radix Rubiae, Herba Portulacae 13 parts, Herba Chenopodii 13 parts, bamboo salt 12 parts, rice vinegar 10 parts.
The preparation method of the preparation of the treatment Lateolabrax japonicus gill rot of the present embodiment is with embodiment 1.
Embodiment 3
In the present invention's the 3rd detailed description of the invention, feed ingredient and preparation method thereof is as follows:
Treat a preparation for Lateolabrax japonicus gill rot, be made up of each component of following masses number: Citrullus vulgaris juice 30 parts, Fructus Gleditsia juice 22 parts, Fructus Momordicae charantiae juice 22 parts, Herba Taraxaci 21 parts, Radix Cynanchi Atrati 21 parts, the Radix Pulsatillae 23 parts, Rhizoma Acori Graminei 19 parts, 19 parts, morning glory, Herba Astragali Melilotoidis (Herba Astragali Sinici) 19 parts, the Cortex Eucommiae 18 parts, Radix Pseudostellariae 18 parts, Serpentis pimple 19 parts, Cortex Moutan 19 parts, Herba Violae 20 parts, Cortex Hibisci 17 parts, 15 parts, Rhizoma Zingiberis Recens, Rhizoma Belamcandae 15 parts, Herba Houttuyniae 14 parts, Plumula Nelumbinis 14 parts, 11 parts, Radix Rubiae, Herba Portulacae 11 parts, Herba Chenopodii 11 parts, bamboo salt 10 parts, rice vinegar 8 parts.
The preparation method of the preparation of the treatment Lateolabrax japonicus gill rot of the present embodiment is with embodiment 1.
Embodiment 4
In the present invention's the 4th detailed description of the invention, feed ingredient and preparation method thereof is as follows:
Treat a preparation for Lateolabrax japonicus gill rot, be made up of each component of following masses number: Citrullus vulgaris juice 28 parts, Fructus Gleditsia juice 22 parts, Fructus Momordicae charantiae juice 21 parts, Herba Taraxaci 20 parts, Radix Cynanchi Atrati 19 parts, the Radix Pulsatillae 20 parts, Rhizoma Acori Graminei 20 parts, 16 parts, morning glory, Herba Astragali Melilotoidis (Herba Astragali Sinici) 18 parts, the Cortex Eucommiae 16 parts, Radix Pseudostellariae 17 parts, Serpentis pimple 17 parts, Cortex Moutan 17 parts, Herba Violae 16 parts, Cortex Hibisci 15 parts, 13 parts, Rhizoma Zingiberis Recens, Rhizoma Belamcandae 12 parts, Herba Houttuyniae 12 parts, Plumula Nelumbinis 11 parts, 9 parts, Radix Rubiae, Herba Portulacae 9 parts, Herba Chenopodii 9 parts, bamboo salt 8 parts, rice vinegar 8 parts.
The preparation method of the preparation of the treatment Lateolabrax japonicus gill rot of the present embodiment is with embodiment 1.
Embodiment 5
In the present invention's the 5th detailed description of the invention, feed ingredient and preparation method thereof is as follows:
Treat a preparation for Lateolabrax japonicus gill rot, be made up of each component of following masses number: Citrullus vulgaris juice 24 parts, Fructus Gleditsia juice 20 parts, Fructus Momordicae charantiae juice 20 parts, Herba Taraxaci 19 parts, Radix Cynanchi Atrati 19 parts, the Radix Pulsatillae 19 parts, Rhizoma Acori Graminei 17 parts, 16 parts, morning glory, Herba Astragali Melilotoidis (Herba Astragali Sinici) 17 parts, the Cortex Eucommiae 15 parts, Radix Pseudostellariae 16 parts, Serpentis pimple 13 parts, Cortex Moutan 13 parts, Herba Violae 13 parts, Cortex Hibisci 14 parts, 12 parts, Rhizoma Zingiberis Recens, Rhizoma Belamcandae 14 parts, Herba Houttuyniae 12 parts, Plumula Nelumbinis 11 parts, 9 parts, Radix Rubiae, Herba Portulacae 9 parts, Herba Chenopodii 8 parts, bamboo salt 10 parts, rice vinegar 6 parts.
The preparation method of the preparation of the treatment Lateolabrax japonicus gill rot of the present embodiment is with embodiment 1.
Embodiment 6
In the present invention's the 6th detailed description of the invention, feed ingredient and preparation method thereof is as follows:
Treat a preparation for Lateolabrax japonicus gill rot, be made up of each component of following masses number: Citrullus vulgaris juice 29 parts, Fructus Gleditsia juice 23 parts, Fructus Momordicae charantiae juice 23 parts, Herba Taraxaci 22 parts, Radix Cynanchi Atrati 22 parts, the Radix Pulsatillae 21 parts, Rhizoma Acori Graminei 21 parts, 20 parts, morning glory, Herba Astragali Melilotoidis (Herba Astragali Sinici) 20 parts, the Cortex Eucommiae 20 parts, Radix Pseudostellariae 19 parts, Serpentis pimple 18 parts, Cortex Moutan 18 parts, Herba Violae 17 parts, Cortex Hibisci 18 parts, 17 parts, Rhizoma Zingiberis Recens, Rhizoma Belamcandae 16 parts, Herba Houttuyniae 15 parts, Plumula Nelumbinis 15 parts, 13 parts, Radix Rubiae, Herba Portulacae 12 parts, Herba Chenopodii 12 parts, bamboo salt 11 parts, rice vinegar 9 parts.
The preparation method of the preparation of the treatment Lateolabrax japonicus gill rot of the present embodiment is with embodiment 1.
Experimental result
Therapeutic effect is tested
In order to verify therapeutic effect of the present invention, in fishing ground, Qingdao, the Lateolabrax japonicus suffering from gill rot is tested.Matched group and experimental group establish respectively 3 parallel.The process of experimental group is as follows: water per ton pours the preparation of the embodiment of the present invention 6 of 30-40ml into, within every 12 hours, changes water once, adds the preparation of the embodiment of the present invention 6 after changing water by same ratio, uses continuously until recovery from illness.Matched group every 100kg fish body weight erythromycin 1.5g joins in feedstuff and throws something and feeds, until sick fish rehabilitation.Experimental result is in table 1:
The preparation for treating effect situation of table 1 treatment Lateolabrax japonicus of the present invention gill rot
Experimental result shows, the component of the preparation for the treatment of Lateolabrax japonicus gill rot of the present invention is environmental protection raw material, nontoxic to environment, do not use chemical drugs or antibiotic, the healthy of people can not be affected after edible Lateolabrax japonicus of having cured, and preparation of the present invention is good to the curative effect of Lateolabrax japonicus gill rot, cure rate is high, in experimentation, the cure rate of preparation to ill Lateolabrax japonicus of the embodiment of the present invention 6 reaches 100%, the cure rate of preparation to ill Lateolabrax japonicus of embodiment 1-5 also reaches more than 90%, in experimentation, after medication 2-4 days, the floating head phenomenon of Lateolabrax japonicus disappears, Lateolabrax japonicus ingestion frequency improves.In addition, the present invention uses safer, little to Lateolabrax japonicus damage, and after using the preparation for the treatment of Lateolabrax japonicus bacterial enteritis of the present invention, Lateolabrax japonicus Health restoration is fast, medication 5-9 days, and Lateolabrax japonicus can recover normal activity, and idle fund is strong and vigorous, ingests completely normal.
Preventive effect is tested
Normally to raise group for blank group, to add the processed group of the embodiment of the present invention 6 in pond for experimental group, experimental group process is as follows: the using method of the present invention when preventing Lateolabrax japonicus gill rot is as follows: water per ton pours the preparation of the embodiment of the present invention 6 of 20-25ml into, water is changed once after 24 hours, add the preparation of the embodiment of the present invention 6 by same ratio after changing water, continuous use, after 2 days, stops 1 day; A circulation 5-8 cycle like this.Matched group and experimental group establish respectively 3 parallel.Choose the identical pond of 6 sizes, healthy Lateolabrax japonicus 60, all assigned at random by healthy Lateolabrax japonicus in 6 ponds, 10 Lateolabrax japonicus in each pond, add the Lateolabrax japonicus that 1 is suffered from gill rot in each pond.The results are shown in Table 2:
The effect situation of the preparation prevention gill rot of table 2 treatment Lateolabrax japonicus of the present invention gill rot
From table 2, the preparation for the treatment of Lateolabrax japonicus gill rot of the present invention effectively can reduce the incidence rate of Lateolabrax japonicus gill rot, can improve the immunity of Lateolabrax japonicus, has good preventive effect to gill rot.
Bacteriostatic test checks
With erythromycin as matched group, the preparation of the treatment Lateolabrax japonicus gill rot of the embodiment of the present invention 6 is that experimental group carries out antibacterial inspection.
The preparation of culture medium: take in the water-soluble 800mL of beef extract 5g, adds peptone 10g and dissolves, and adds casein 34g and dissolves, then adds NaCl5g dissolving, is adjusted to pH7.6 ~ 7.8, is diluted to 1000mL.Add agar powder 18g, autoclaving 15min, when being cooled to 40 DEG C ~ 50 DEG C, a kind of rhyme scheme in Chinese operas serving as the prelude to a complete score for voices, solidifies, and the 4 DEG C of refrigerators placing no bacteria pollution are for subsequent use.
Strain is: Cytophaga Columnaris.
Matched group antibacterial liquid is prepared: be dissolved in 10ml sterile deionized water by 1 part of erythromycin, diluted respectively by liquor strength, with stock solution than being 1:2,1:4,1:8,1:16,1:32.
Experimental group antibacterial liquid is prepared: by the formulation dissolution of the treatment Lateolabrax japonicus gill rot of the embodiment of the present invention 6 in 10ml sterile deionized water, diluted respectively by liquor strength, with stock solution than being 1:2,1:4,1:8,1:16,1:32.To the fungistatic effect of Cytophaga Columnaris in table 3:
The bactericidal and bacteriostatic effect of the preparation of table 3 treatment Lateolabrax japonicus of the present invention gill rot
From table 3, the pathogen Cytophaga Columnaris of preparation to gill rot of the treatment Lateolabrax japonicus gill rot of embodiments of the invention 6 has good bactericidal and bacteriostatic effect.
The above is only the preferred embodiment of the present invention, is noted that for those skilled in the art, and under the premise without departing from the principles of the invention, can also make some improvement, these improvement should be considered as protection scope of the present invention.
Claims (9)
1. treat the preparation of Lateolabrax japonicus gill rot for one kind, it is characterized in that: be made up of each component of following masses number: Citrullus vulgaris juice 24-34 part, Fructus Gleditsia juice 20-26 part, Fructus Momordicae charantiae juice 20-26 part, Herba Taraxaci 19-25 part, Radix Cynanchi Atrati 19-25 part, Radix Pulsatillae 19-25 part, Rhizoma Acori Graminei 17-24 part, morning glory 16-24 part, Herba Astragali Melilotoidis (Herba Astragali Sinici) 17-23 part, Cortex Eucommiae 15-24 part, Radix Pseudostellariae 16-23 part, Serpentis pimple 13-23 part, Cortex Moutan 13-23 part, Herba Violae 13-22 part, Cortex Hibisci 14-22 part, Rhizoma Zingiberis Recens 12-21 part, Rhizoma Belamcandae 12-19 part, Herba Houttuyniae 12-18 part, Plumula Nelumbinis 11-18 part, Radix Rubiae 9-16 part, Herba Portulacae 9-15 part, Herba Chenopodii 8-16 part, bamboo salt 8-14 part, rice vinegar 6-12 part.
2. the preparation for the treatment of Lateolabrax japonicus gill rot according to claim 1, it is characterized in that: the preparation of described treatment Lateolabrax japonicus gill rot, be made up of each component of following masses number: Citrullus vulgaris juice 28-30 part, Fructus Gleditsia juice 22-24 part, Fructus Momordicae charantiae juice 22-24 part, Herba Taraxaci 21-23 part, Radix Cynanchi Atrati 21-23 part, Radix Pulsatillae 20-23 part, Rhizoma Acori Graminei 19-22 part, morning glory 19-21 part, Herba Astragali Melilotoidis (Herba Astragali Sinici) 19-21 part, Cortex Eucommiae 18-21 part, Radix Pseudostellariae 18-20 part, Serpentis pimple 17-19 part, Cortex Moutan 17-19 part, Herba Violae 16-18 part, Cortex Hibisci 17-19 part, Rhizoma Zingiberis Recens 15-18 part, Rhizoma Belamcandae 15-17 part, Herba Houttuyniae 14-16 part, Plumula Nelumbinis 14-15 part, Radix Rubiae 11-14 part, Herba Portulacae 11-13 part, Herba Chenopodii 11-13 part, bamboo salt 10-12 part, rice vinegar 8-10 part.
3. the preparation for the treatment of Lateolabrax japonicus gill rot according to claim 1, it is characterized in that: the preparation of described treatment Lateolabrax japonicus gill rot, be made up of each component of following masses number: Citrullus vulgaris juice 29 parts, Fructus Gleditsia juice 23 parts, Fructus Momordicae charantiae juice 23 parts, Herba Taraxaci 22 parts, Radix Cynanchi Atrati 22 parts, the Radix Pulsatillae 21 parts, Rhizoma Acori Graminei 21 parts, 20 parts, morning glory, Herba Astragali Melilotoidis (Herba Astragali Sinici) 20 parts, the Cortex Eucommiae 20 parts, Radix Pseudostellariae 19 parts, Serpentis pimple 18 parts, Cortex Moutan 18 parts, Herba Violae 17 parts, Cortex Hibisci 18 parts, 17 parts, Rhizoma Zingiberis Recens, Rhizoma Belamcandae 16 parts, Herba Houttuyniae 15 parts, Plumula Nelumbinis 15 parts, 13 parts, Radix Rubiae, Herba Portulacae 12 parts, Herba Chenopodii 12 parts, bamboo salt 11 parts, rice vinegar 9 parts.
4. a preparation method for the preparation of the treatment Lateolabrax japonicus gill rot according to any one of claim 1-3, is characterized in that: comprise the following steps:
(1) take Herba Taraxaci, Radix Cynanchi Atrati, the Radix Pulsatillae and Rhizoma Acori Graminei respectively according to proportioning, gross weight is designated as 1 part, adds 12 parts of purified water, and 70-80 DEG C is soaked 1h, obtain soak;
(2) boil 2h after the soak that step (1) obtains being heated to boiling, be separated and take out fried liquid, continue the purified water adding 6 parts in medical material, continue to boil 1h after being heated to boiling, merge twice fried liquid and be extracting solution;
(3) morning glory, Herba Astragali Melilotoidis (Herba Astragali Sinici), the Cortex Eucommiae, Radix Pseudostellariae, Serpentis pimple, Cortex Moutan, Herba Violae, Cortex Hibisci, Rhizoma Zingiberis Recens, Rhizoma Belamcandae, Herba Houttuyniae, Plumula Nelumbinis, Radix Rubiae, Herba Portulacae, Herba Chenopodii is taken respectively according to proportioning, load ball mill grinding 2h, cross 80 mesh sieves, obtain grounds travel;
(4) grounds travel that extracting solution step (2) obtained and step (3) obtain is positioned in the extraction kettle in supercritical extraction instrument, carbon dioxide is utilized to extract as medium, extraction kettle pressure is 40Mpa, extraction temperature is 45 DEG C, separator pressure 12Mpa, separator temperature is 70 DEG C, extracts 2 hours, is extracted liquid;
(5) step Citrullus vulgaris juice, Fructus Gleditsia juice, Fructus Momordicae charantiae juice, bamboo salt and rice vinegar is taken respectively according to proportioning, load weighted Citrullus vulgaris juice, Fructus Gleditsia juice, Fructus Momordicae charantiae juice, bamboo salt and the rice vinegar extract with step (4) gained is mixed homogeneously, obtains object.
5. the preparation method of the preparation for the treatment of Lateolabrax japonicus gill rot according to claim 4, is characterized in that: the preparation method of described Citrullus vulgaris juice is: ground or put into juice extractor by flesh of Pulp Citrulli and squeeze the juice, gained juice is Citrullus vulgaris juice.
6. the preparation method of the preparation for the treatment of Lateolabrax japonicus gill rot according to claim 4, is characterized in that: the preparation method of described Fructus Gleditsia juice is: ground or put into juice extractor by Fructus Gleditsia and squeeze the juice, gained juice is Fructus Gleditsia juice.
7. the preparation method of the preparation for the treatment of Lateolabrax japonicus gill rot according to claim 4, is characterized in that: the preparation method of described Fructus Momordicae charantiae juice is: ground or put into juice extractor by Fructus Momordicae charantiae and squeeze the juice, gained juice is Fructus Momordicae charantiae juice.
8. the using method of preparation when treating Lateolabrax japonicus gill rot of the treatment Lateolabrax japonicus gill rot according to any one of a claim 1-3, it is characterized in that: water per ton pours the preparation of the present invention of 30-40ml into, within every 12 hours, change water once, add preparation of the present invention by same ratio after changing water, use continuously until recovery from illness.
9. the using method of preparation when preventing Lateolabrax japonicus gill rot of the treatment Lateolabrax japonicus gill rot according to any one of a claim 1-3, it is characterized in that: water per ton pours the preparation of the present invention of 20-25ml into, water is changed once after 24 hours, preparation of the present invention is added by same ratio after changing water, continuous use, after 2 days, stops 1 day; A circulation 5-8 cycle like this.
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