CN104491202A - Traditional Chinese medicinal composition for treating tail-rot disease of cynoglossus semilaevis - Google Patents
Traditional Chinese medicinal composition for treating tail-rot disease of cynoglossus semilaevis Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/413—Gall bladder; Bile
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/536—Prunella or Brunella (selfheal)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/748—Oldenlandia or Hedyotis
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/86—Violaceae (Violet family)
Abstract
The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicinal composition for treating tail-rot disease of cynoglossus semilaevis. The traditional Chinese medicinal composition is prepared from the following raw materials in parts by weight: 40-60 parts of honeysuckle, 20-40 parts of wild chrysanthemum, 40-60 parts of dandelion, 30-50 parts of bunge corydalis herb, 50-70 parts of astragalus membranaceus, 40-60 parts of oldenlandia diffusa, 20-40 parts of selfheal, 20-40 parts of sculellaria barbata, 30-50 parts of herba patriniae, 10-20 parts of isatis root, 10-20 parts of purslane, 10-20 parts of fructus forsythiae, 10-20 parts of verbena officinalis, 10-20 parts of herba rabdosiae, 10-20 parts of ash bark and 10-20 parts of bezoar. By virtue of a preparation method, the traditional Chinese medicinal composition is in the form of a decoction or the composition is prepared into fine powder by the following steps: weighing raw materials according to parts by weight, cleaning, drying and grinding the raw materials, and filtering the ground materials by virtue of a sieve of 80-100 meshes. Through the effects of diminishing inflammation and resisting bacteria, the traditional Chinese medicinal composition disclosed by the invention can be used for treating tail-rot disease of cynoglossus semilaevis, and meanwhile the traditional Chinese medicinal composition can be used for reducing the death of cynoglossus semilaevis caused by other pathogenic factors.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly a kind of Chinese medicine composition for the treatment of Cynoglossus semilaevis tail-rot disease.
Background technology
Cynoglossus semilaevis belongs to Pleuronectiformes, Cynoglossidae, tongue sole belong to, and be the large-scale demersal fishes in a kind of warm warm nature coastal waters, wild varieties life is perched in CHINESE OFFSHORE sea area, the wide temperature of tool, wide salt and adapt to the feature of changeable environmental condition.Through years of researches tackling key problem, Cynoglossus semilaevis artificial breeding and cultural technique make a breakthrough, and all have cultivation at the yellow Bohai Sea of China, the East Sea, the South Sea.But along with the increase of cultured area, the diseases prevention and treatment of Cynoglossus semilaevis have become puts in raiser face previous urgent problem, this wherein tail-rot disease be one of common disease occurred frequently of Cynoglossus semilaevis mature stage, disease symptom shows as that tail fin rots, end turns white, rotten to the corn wound spreads to fish body front portion gradually and reaches the long 1/5-1/4 of body, especially young stage death rate of the onset is high, can reach 100%, causes serious economic loss to raiser.
Current technical scheme, to improve the preventive measures such as cultivating condition, is such as improved water quality, is increased and renew the water frequency, improve quality of the fodder and supervision etc. in intensifies process.Treatment report for sick fish is less, and Zhang Zheng etc. propose sick fish to pull out with 5 mg/litre oxytetracycline dippings for 2012 39 (2) at " aquatic science and technology information ", prevention bacterial wound infection.Palace spring scenery etc. are in the tetramycin hydrochloride dipping of " Chinese Fishery " 12 interim proposition concentration 10mg/L-15mg/L in 2005.But because Cynoglossus semilaevis tail-rot disease period of disease is many at mature stage, ichthyoid is less, not easily finds at the initial stage of a disease, the infection having reached certain scale to be found, only for sick fish dispenser, poor effect.Meanwhile, easily cause the limited and hepar damnification of juvenile growth in the treatment of cultivation phase oxytetracycline, cause the complication such as fish body festers.Therefore be badly in need of a kind of effective, easy metabolism, the medicine little to the side effect of fish body is treated, solve the fish body problem of death that Cynoglossus semilaevis tail-rot disease causes, avoid large economic loss.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of Cynoglossus semilaevis tail-rot disease, by the antiphlogistic antibacterial effect of Chinese medicine composition, treat for Cynoglossus semilaevis tail-rot disease, Cynoglossus semilaevis resistance can be increased simultaneously, reduce the Cynoglossus semilaevis death that other causes of disease cause.
The invention provides a kind of Chinese medicine composition for the treatment of Cynoglossus semilaevis tail-rot disease, formed by the preparation of raw material of following parts by weight: Flos Lonicerae 40-60 part, Flos Chrysanthemi Indici 20-40 part; Herba Taraxaci 40-60 part, Herba Violae 30-50 part, Radix Astragali 50-70 part; Herba Hedyotidis Diffusae 40-60 part, Spica Prunellae 20-40 part, Herba Scutellariae Barbatae 20-40 part; Herba Patriniae 30-50 part, Radix Isatidis 10-20 part, Herba Portulacae 10-20 part; Fructus Forsythiae 10-20 part, Herba Verbenae 10-20 part, Rabdosia rubescens 10-20 part; Cortex Fraxini 10-20 part, Calculus Bovis 10-20 part.
More preferably formed by the preparation of raw material of following parts by weight: Flos Lonicerae 50 parts, Flos Chrysanthemi Indici 30 parts, Herba Taraxaci 50 parts; Herba Violae 40 parts, the Radix Astragali 60 parts, Herba Hedyotidis Diffusae 50 parts; Spica Prunellae 30 parts, Herba Scutellariae Barbatae 30 parts, Herba Patriniae 40 parts; Radix Isatidis 15 parts, Herba Portulacae 15 parts, Fructus Forsythiae 15 parts; Herba Verbenae 15 parts; Rabdosia rubescens 15 parts, Cortex Fraxini 15 parts, Calculus Bovis 15 parts.
Preparation method is water decoction or takes raw material by above-mentioned weight portion, cleans, dries, pulverizes, and crosses 80-100 mesh sieve, obtains fine powder.
Pharmacology analysis:
Flos Lonicerae: medical material Flos Lonicerae is Caprifoliaceae woodbine Radix Ophiopogonis and congener dry flower or is with the flower just opened.Flos Lonicerae is the good medicine of heat-clearing and toxic substances removing.Its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, sends out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, equal Be very effective.
Flos Chrysanthemi Indici: be Compositae herbaceos perennial, the capitate profile of Flos Chrysanthemi Indici is similar to Flos Chrysanthemi, wild in wild areas such as patana, Tian Bian, roadsides.Be good with yellow skin without stalk, complete, toil, the non-standard-sized sheet person of flower.Flos Chrysanthemi Indici cold nature, tool dispelling wind and heat pathogens, subduing swelling and detoxicating.Furuncle carbuncle, laryngopharynx swelling and pain, wind-fire acute conjunctivitis can be treated, the disease such as dizzy of having a headache.
Herba Taraxaci: another name Herba crotalariae albidae, Po Poding, Hua Hualang etc.Containing multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, inulin in plant.Nature and flavor are sweet, micro-hardship, cold.Return liver, stomach warp.There are the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.
Herba Violae: another name Herba corydalis edulis, Peng Shi Herba corydalis edulis, Bu Shi Herba Violae etc., with dry herb hyoscine, have effect of heat-clearing and toxic substances removing, cure mainly the diseases such as carbuncle, furuncle, anemopyretic cold, bronchitis, hepatitis, enteritis.
The Radix Astragali, has another name called continuous stilbene.Perennial herb.It has enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Herba Hedyotidis Diffusae: another name: Herba Hedyotidis Diffusae, tang Huang, Serpentis needle grass, Radix Picriae felterrae, two leaf humulus, spend that cross grass, sharp knife grass, JIAMENGCAO, Herba Otteliae Alismoidis, Serpentis Lei are careless, crane SHECAO in vain.Draft is hung down loosely for annual, its patent medicine bitter in the mouth, light, cold in nature.Primary efficacy is heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness.Outstanding kind treatment all kinds inflammation.In clinical practice, if find, Herba Hedyotidis Diffusae compatibility is proper, can treat various diseases.
Spica Prunellae: another name wheat head Spica Prunellae, iron wire Spica Prunellae, Mai Xia is withered, the iron wire summer is withered, sunset sentence, Nedong etc.; There is the effect of improving eyesight of relieving inflammation or internal heat, can conjunctival congestion and swelling pain, headache etc. be controlled.
Herba Scutellariae Barbatae: another name Herba Portulacae Grandiflorae, Folium Pini Paeonia suffruticosa, dragon palpus Paeonia suffruticosa, spun gold Cuculus polioephalus, foreign Herba Portulacae, heronsbill, Herba Portulacae Grandiflorae are horse Labiatae Scutellaria herbaceos perennials.Herba Portulacae Grandiflorae all herbal medicine, has heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, the function such as anticancer.Sour in the mouth cold in nature, herb is containing compositions such as multivitamin, trace element and aminoacid.There is effect of removing pathogenic heat from blood and toxic substance from the body, eliminating stasis to stop pain, detumescence and clearing away heat-damp and promoting diuresis.
Herba Patriniae: be the dry herb of Valerianaceae plant patrima villosa.Cool in nature, acrid in the mouth, hardship.Have heat-clearing and toxic substances removing, the effect of evacuation of pus of eliminating the phlegm, be usually used in acute appendicitis, lung abscess, dysentery, postnatal blood stasis stomachache, carbuncle furuncle.
Radix Isatidis: bitter, cold, nontoxic.Return liver, stomach warp; Effect heat clearing away, removing toxic substances, removing heat from blood, sore-throat relieving, cure mainly maculae caused by violent heat pathogen, high hot headache, major part pestilence, crimson tongue be purple secretly, scarlet fever, erysipelas, mumps, sore throat, skin ulcer are swollen, carbuncle, chickenpox, measles, hepatitis, influenza, epidemic encephalitis, encephalitis b, pneumonia, coma tell nosebleed, pharyngeal swelling, acute catarrhal conjunctivitis, skin ulcer rash; Epidemic encephalitis type B, acute, chronic hepatitis, mumps, osteomyelitis can be prevented and treated.Modern pharmacology proves, Radix Isatidis has obvious inhibitory action to multiple virus and pathogenic bacteria.
Herba Portulacae: function clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, antiinflammatory, quench the thirst, diuresis; Cure mainly hematodiarrhoea pus and blood, pyretic stranguria, stranguria with blood, leukorrhagia, carbuncle malignant boil, erysipelas, trace scrofula.
Fructus Forsythiae: bitter, is slightly cold; Return lung, the heart, gallbladder meridian.Effect heat-clearing and toxic substances removing, wind-dispelling heat-dissipating, eliminating carbuncle eliminating stagnation, QI and blood of not only faling apart cohesion again can eliminating carbuncle eliminating stagnation, for clearing away heart-fire, loose part of the body cavity above the diaphragm housing the heart and lungs wind heat.
Herba Verbenae: cool in nature, bitter in the mouth; Enter liver, spleen channel.Function heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, inducing diuresis to remove edema; Cure mainly fever caused by exogenous pathogens, jaundice due to damp-heat, edema, dysentery, malaria, diphtheria, sore throat, gonorrhea, amenorrhea, lump in the abdomen, carbuncle sore tumefacting virus, ulcerative gingivitis.
Rabdosia rubescens: bitter in the mouth, sweet, cold nature; Return lung, stomach, Liver Channel.Effect heat-clearing and toxic substances removing, promoting blood circulation and stopping pain; For laryngopharynx swelling and pain, abdominal mass abdominal mass mass in the abdomen, snake bite and insect sting.
Cortex Fraxini: bitter in the mouth, puckery, cold in nature.Effect heat clearing and damp drying, astringent therapy dysentery relieving, leukorrhagia stopping, improving eyesight; For pyretic toxicity dysentery, leucorrhea with red and white discharge, conjunctival congestion and swelling pain, the raw cataracta of order.
Calculus Bovis: mildly bitter flavor is then sweet, cool in nature.Can be used for antipyretic, removing toxic substances, arresting convulsion.The disease such as Zhi Gaore coma for oral administration, demented, infantile convulsion, tic, external is controlled laryngopharynx swelling and pain, aphtha carbuncle, is treated toxication.
The present invention, by the antiphlogistic antibacterial effect of Chinese medicine composition, treats for Cynoglossus semilaevis tail-rot disease, can reduce the Cynoglossus semilaevis death that other causes of disease cause simultaneously.
Outcome measure:
In the adult fish phase, from discovery Article 1 tail-rot disease Cynoglossus semilaevis, according to the weight of fish in fishpond, and twice bait throwing in material is synchronous sooner or later, and powder carries out dipping according to the ratio of 0.3%.Decoction, throws according to the ratio of 0.6ml/kg, throws in 7-10 days continuously, and observes the tail-rot disease treatment situation of Cynoglossus semilaevis.
Contrast adopts the tetramycin hydrochloride dipping of 15mg/L.Contrast the mortality rate of Cynoglossus semilaevis and the ratio of wherein tail-rot disease respectively, experimental result is as follows:
Experimental result shows, the dipping of contrast ordinary salt OXYTETRACYCLINE HCL, Chinese medicine composition has good therapeutical effect to Cynoglossus semilaevis tail-rot disease, and can reduce the mortality rate of Cynoglossus semilaevis, strengthening its resistance, is a kind of Therapeutic Method having very big promotional value simultaneously.
Detailed description of the invention
Embodiment 1:
Treat a Chinese medicine composition for Cynoglossus semilaevis tail-rot disease, formed by the preparation of raw material of following parts by weight: Flos Lonicerae 50 parts, Flos Chrysanthemi Indici 30 parts; Herba Taraxaci 50 parts, Herba Violae 40 parts, the Radix Astragali 60 parts; Herba Hedyotidis Diffusae 50 parts, Spica Prunellae 30 parts, Herba Scutellariae Barbatae 30 parts; Herba Patriniae 40 parts, Radix Isatidis 15 parts, Herba Portulacae 15 parts; Fructus Forsythiae 15 parts, Herba Verbenae 15 parts, Rabdosia rubescens 15 parts; Cortex Fraxini 15 parts, Calculus Bovis 15 parts.
Embodiment 2:
Treat a Chinese medicine composition for Cynoglossus semilaevis tail-rot disease, formed by the preparation of raw material of following parts by weight: Flos Lonicerae 40 parts, Flos Chrysanthemi Indici 40 parts; Herba Taraxaci 40 parts, Herba Violae 50 parts, the Radix Astragali 50 parts; Herba Hedyotidis Diffusae 60 parts, Spica Prunellae 20 parts, Herba Scutellariae Barbatae 40 parts; Herba Patriniae 30 parts, Radix Isatidis 20 parts, Herba Portulacae 10 parts; Fructus Forsythiae 20 parts, Herba Verbenae 10 parts, Rabdosia rubescens 20 parts; Cortex Fraxini 10 parts, Calculus Bovis 20 parts.
Embodiment 3:
Treat a Chinese medicine composition for Cynoglossus semilaevis tail-rot disease, formed by the preparation of raw material of following parts by weight: Flos Lonicerae 60 parts, Flos Chrysanthemi Indici 20 parts; Herba Taraxaci 60 parts, Herba Violae 30 parts, the Radix Astragali 70 parts; Herba Hedyotidis Diffusae 40 parts, Spica Prunellae 40 parts, Herba Scutellariae Barbatae 20 parts; Herba Patriniae 50 parts, Radix Isatidis 10 parts, Herba Portulacae 20 parts; Fructus Forsythiae 10 parts, Herba Verbenae 20 parts, Rabdosia rubescens 10 parts; Cortex Fraxini 20 parts, Calculus Bovis 10 parts.
Claims (2)
1. treat a Chinese medicine composition for Cynoglossus semilaevis tail-rot disease, it is characterized in that being formed by the preparation of raw material of following parts by weight: Flos Lonicerae 40-60 part, Flos Chrysanthemi Indici 20-40 part; Herba Taraxaci 40-60 part, Herba Violae 30-50 part, Radix Astragali 50-70 part; Herba Hedyotidis Diffusae 40-60 part, Spica Prunellae 20-40 part, Herba Scutellariae Barbatae 20-40 part; Herba Patriniae 30-50 part, Radix Isatidis 10-20 part, Herba Portulacae 10-20 part; Fructus Forsythiae 10-20 part, Herba Verbenae 10-20 part, Rabdosia rubescens 10-20 part; Cortex Fraxini 10-20 part, Calculus Bovis 10-20 part.
2. a kind of Chinese medicine composition for the treatment of Cynoglossus semilaevis tail-rot disease as claimed in claim 1, is characterized in that being formed by the preparation of raw material of following parts by weight: Flos Lonicerae 50 parts, Flos Chrysanthemi Indici 30 parts; Herba Taraxaci 50 parts, Herba Violae 40 parts, the Radix Astragali 60 parts; Herba Hedyotidis Diffusae 50 parts, Spica Prunellae 30 parts, Herba Scutellariae Barbatae 30 parts; Herba Patriniae 40 parts, Radix Isatidis 15 parts, Herba Portulacae 15 parts; Fructus Forsythiae 15 parts, Herba Verbenae 15 parts, Rabdosia rubescens 15 parts; Cortex Fraxini 15 parts, Calculus Bovis 15 parts.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410752908.8A CN104491202A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medicinal composition for treating tail-rot disease of cynoglossus semilaevis |
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| CN201410752908.8A CN104491202A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medicinal composition for treating tail-rot disease of cynoglossus semilaevis |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410752908.8A Pending CN104491202A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medicinal composition for treating tail-rot disease of cynoglossus semilaevis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105124251A (en) * | 2015-08-31 | 2015-12-09 | 青岛海之源智能技术有限公司 | Fish feed capable of preventing tail rot disease of onychostoma simus and preparation method of fish feed |
| CN105434706A (en) * | 2016-01-18 | 2016-03-30 | 张嗣喜 | Traditional Chinese medicine composition for treating gill rote disease of fish |
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| CN102961660A (en) * | 2012-12-14 | 2013-03-13 | 张�杰 | Chinese herbal medicine for treating fish diseases |
| CN103385390A (en) * | 2013-08-02 | 2013-11-13 | 青岛七好营养科技有限公司 | Artificial particle feed for juvenile turbot |
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| CN102961660A (en) * | 2012-12-14 | 2013-03-13 | 张�杰 | Chinese herbal medicine for treating fish diseases |
| CN103385390A (en) * | 2013-08-02 | 2013-11-13 | 青岛七好营养科技有限公司 | Artificial particle feed for juvenile turbot |
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| 权可艳等: "《常用渔药使用手册》", 31 March 2011, 四川科学技术出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105124251A (en) * | 2015-08-31 | 2015-12-09 | 青岛海之源智能技术有限公司 | Fish feed capable of preventing tail rot disease of onychostoma simus and preparation method of fish feed |
| CN105434706A (en) * | 2016-01-18 | 2016-03-30 | 张嗣喜 | Traditional Chinese medicine composition for treating gill rote disease of fish |
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Application publication date: 20150408 |