CN105796799A - Traditional Chinese medicine composition for treating coughs - Google Patents

Traditional Chinese medicine composition for treating coughs Download PDF

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Publication number
CN105796799A
CN105796799A CN201610193075.5A CN201610193075A CN105796799A CN 105796799 A CN105796799 A CN 105796799A CN 201610193075 A CN201610193075 A CN 201610193075A CN 105796799 A CN105796799 A CN 105796799A
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CN
China
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parts
chinese medicine
medicine composition
radix gentianae
traditional chinese
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CN201610193075.5A
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Chinese (zh)
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覃美红
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Individual
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Priority to CN201610193075.5A priority Critical patent/CN105796799A/en
Publication of CN105796799A publication Critical patent/CN105796799A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia

Abstract

The invention belongs to the technical field of traditional Chinese medicine preparation research and development, and particularly discloses a traditional Chinese medicine composition for treating coughs.The traditional Chinese medicine composition for treating coughs is prepared from, by weight, 10-50 parts of tuber fleeceflower stems, 5-30 parts of Chinese gentian roots, 5-40 parts of rhizoma pinelliae, 3-30 parts of all-grass of salvia prionitis Hance, 3-50 parts of poria cocos, 3-40 parts of herba epimedii, 5-35 parts of Chinese gentian roots, 5-30 parts of roots of spinyleaf pricklyash and 5-40 parts of rhizoma corydalis.The traditional Chinese medicine composition is easy to prepare, significant in treatment effect, small in side effect and good in safety, has a treatment effect on coughs and has a significant treatment effect especially on dry coughs.

Description

A kind of Chinese medicine composition treating cough
Technical field
The invention belongs to pharmaceutical preparation research and development technology field, a kind of Chinese medicine composition treating cough Thing.
Background technology
Cough is a kind of protectiveness respiratory reflex action of human body.Breathing can be effectively removed by coughre flex Secretions in road or the foreign body of entrance air flue.But cough also has disadvantageous one side, acutely cough may result in Respiratory tract hemorrhage, as a long time, frequently, acutely cough affects work, has a rest, even causes laryngalgia, sound Mute and breathe myalgia, then belong to pathological phenomenon.Usual people's typically all employing is taken chemical drugs and is controlled Treat, but, cough the most not fully up to expectations with the treatment of existing chemical drugs, and take chemical drugs and easily produce Raw side effect in various degree.
The traditional Chinese medical science of China is of long standing and well established, and of extensive knowledge and profound scholarship, Chinese medicine is with its safety, few side effects, to gastrointestinal tract Not damaged and the advantage little to Liver and kidney stimulation, favored by extensive patients deeply.
Therefore, Study of Traditional Chinese Medicine product always is the heat in drug development research field for treating various disease Point.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine composition treating cough, i.e. to prevention and treatment cough There is the Chinese medicine composition of excellent effect.Technical scheme can overcome solution treatment in prior art The present situation of cough long-term taking chemicals, reduces security risk and the generation of side effect of patient.This Bright provided technical scheme is:
A kind of Chinese medicine composition treating cough, counts by weight and is made up of following raw material of Chinese medicine: Polygonm multiflorum Thunb Rattan 10-50 part, Radix Gentianae 5-30 part, Rhizoma Pinelliae 5-40 part, Arisaema balansae Engl. grass 3-30 part, Poria 5-30 part, Herba Epimedii 3-40 part, Radix Gentianae 5-35 part, Radix Zanthoxyli Spinifolii 5-30 part and Rhizoma Corydalis 5-40 part.
As preferably, described treats the Chinese medicine composition coughed, and counts by following Chinese medicine former by weight Material composition: Caulis Polygoni Multiflori 20-40 part, Radix Gentianae 10-20 part, Rhizoma Pinelliae 10-20 part, Arisaema balansae Engl. grass 3-20 part, Poria 5-20 part, Herba Epimedii 5-20 part, Radix Gentianae 5-25 part, Radix Zanthoxyli Spinifolii 10-20 part and Rhizoma Corydalis 10-20 Part.
As preferably, described treats the Chinese medicine composition coughed, and counts by following Chinese medicine former by weight Material composition: Caulis Polygoni Multiflori 30 parts, Radix Gentianae 15 parts, the Rhizoma Pinelliae 10 parts, Arisaema balansae Engl. grass 10 parts, 10 parts of Poria, Herba Epimedii 10 parts, Radix Gentianae 10 parts, Radix Zanthoxyli Spinifolii 10 parts and Rhizoma Corydalis 10 parts.
Present invention also offers a kind of medicine, including above-mentioned Chinese medicine composition and pharmaceutically acceptable Adjuvant.
As preferably, described pharmaceutically acceptable adjuvant be starch, sucrose, dextrin, lactose micropowder, At least one in silica gel, aspartame, mannitol, sodium benzoate, sucrose and Mel.
As preferably, the dosage form of described medicine is decoction, powder, granule or tablet.
Compared with prior art, there is advantages that
(1) between the present composition each raw material of Chinese medicine, collocation rationally, has synergistic function, has and control Treating the effect of cough, especially treatment dry cough effect is notable.
(2) present composition uses medium-height grass raw material to make, and toxic and side effects is little, and safety is good, and causes a disease Bacterium is not likely to produce drug resistance.
(3) present composition processing technique is simple, and cost of material is low, it is easy to large-scale promotion and use.
Detailed description of the invention
Below in conjunction with concrete example, the present invention is further detailed explanation.The medium-height grass being previously mentioned in embodiment States Pharmacopoeia specifications medicinal part pressed by medicine
Embodiment 1: the preparation of Chinese medicine decoction and clinical effectiveness
By following component part by weight ratio count: Caulis Polygoni Multiflori 1000g, Radix Gentianae 500g, Rhizoma Pinelliae 500g, Arisaema balansae Engl. grass 300g, Poria 500g, Herba Epimedii 300g, Radix Gentianae 500g, Radix Zanthoxyli Spinifolii 500g and Rhizoma Corydalis 500g。
The preparation method of this Chinese medicine composition decoction, comprises the following steps: take above-mentioned several raw material of Chinese medicine, Add 8 times amount water after drying, after boiling with intense fire, then the 2.5h that simmers in water, filter and discard medicinal residues, to obtain final product Chinese medicine decoction.
Multiple season of coughing, the present embodiment gained decoction is used for clinic, amounts to statistics 200 examples.Its In 100 examples take this decoction in advance, daily 3 times, each 100mL, take 1 day, compare 100 Example is not for take any medicine, and result shows, takes only 3 examples in 100 examples of decoction and suffers from cough, and Other 100 examples are not taken has 85 examples to suffer from cough in this decoction.Visible, epidemic season of coughing, take in advance Can effectively occur by preventing cough with this decoction.
Embodiment 2: the preparation of Chinese powder medicine and clinical effectiveness
By following component part by weight ratio count: Caulis Polygoni Multiflori 5000g, Radix Gentianae 3000g, Rhizoma Pinelliae 4000g, Arisaema balansae Engl. grass 3000g, Poria 3000g, Herba Epimedii 4000g, Radix Gentianae 3500g, Radix Zanthoxyli Spinifolii 3000g and Rhizoma Corydalis 4000g.
The preparation method of this Chinese medicine composition composition powders, comprises the following steps: it is former that (1) takes above-mentioned several Chinese medicine Material, dries in the shade at normal temperatures;(2) water of medical material amount 10 times amount, beta-schardinger dextrin-50g, heating extraction 3 are added Secondary, extract 1.5h every time, then filter, obtain filtrate;(3) filtrate is through being concentrated under reduced pressure to give relative density For the thick paste of 1.30-1.35, dry, pulverize, obtain fine powder;(4) by above-mentioned fine powder, mix homogeneously, i.e. Obtain this Chinese powder medicine.
In clinical trial, the present embodiment gained Chinese powder medicine is used for patient treatment cough, takes 3 every day Secondary, each 20g, take 2 days, add up 100 examples altogether, wherein 85 example patient coughs are almost recovered.
Embodiment 3: the preparation of Chinese medicine granules and clinical effectiveness
By following component part by weight ratio count: Caulis Polygoni Multiflori 3000g, Radix Gentianae 2000g, Rhizoma Pinelliae 2000g, Arisaema balansae Engl. grass 2500g, Poria 2000g, Herba Epimedii 3000g, Radix Gentianae 2500g, Radix Zanthoxyli Spinifolii 2000g and Rhizoma Corydalis 2500g.
The preparation method of this Chinese medicinal composition granules, comprises the following steps: that (1) takes above-mentioned several Chinese medicine Raw material, dries in the shade at normal temperatures;(2) water of medical material amount 11 times amount is added, heating extraction 2 times, each 1.5 Hour, then filter, obtain filtrate;(3) filtrate is 1.10-1.25's through being concentrated under reduced pressure to give relative density Thick paste, dry, pulverize, and obtains fine powder;(4) mixing fine powders 1 part is weighed by weight, sucrose 4 parts, 3 parts of dextrin, mixing, pelletize, 60-70 DEG C is dried, sieves, obtain this Chinese medicine granules.
In clinical trial, the present embodiment gained Chinese medicine granules is used for patient treatment cough, takes every day With 3 times, each 30g, take 3 days, add up 100 examples altogether, wherein 89 example patient coughs are almost recovered.
Embodiment 4: the preparation of Chinese medicinal tablet and clinical effectiveness
By following component part by weight ratio count: Caulis Polygoni Multiflori 3000g, Radix Gentianae 2000g, Rhizoma Pinelliae 1500g, Arisaema balansae Engl. grass 2000g, Poria 2000g, Herba Epimedii 2500g, Radix Gentianae 2500g, Radix Zanthoxyli Spinifolii 1500g and Rhizoma Corydalis 3000g.
The preparation method of this Chinese medicine composition tablet, comprises the following steps: that (1) takes above-mentioned several Chinese medicine former Material, dries in the shade at normal temperatures;(2) water of medical material amount 10 times amount is added, heating extraction 3 times, each 2 hours, Then filter, obtain filtrate;(3) filtrate is through being concentrated under reduced pressure to give the thick paste that relative density is 1.10-1.25, Dry, pulverize, obtain fine powder;(4) mixing fine powders 1 part, lactose micropowder 2 parts, benzene are weighed by weight Sodium formate 1 part, mixing, tabletting, 60-70 DEG C is dried, sieves, obtain this Chinese medicinal tablet.
In clinical trial, the present embodiment gained Chinese medicine granules is used for patient treatment cough, takes every day With 3 times, each 10g, take 3 days, add up 100 examples altogether, wherein 96 example patient coughs are almost recovered.
The aforementioned description to the specific illustrative embodiment of the present invention illustrates that and the purpose of illustration. These descriptions are not wishing to limit the invention to disclosed precise forms, and it will be apparent that according to above-mentioned Teaching, can much change and change.The purpose selected exemplary embodiment and describe exists In explaining the certain principles of the present invention and actual application thereof, so that those skilled in the art can be real Now and utilize the various different exemplary of the present invention and various different selection and change. The scope of the present invention is intended to be limited by claims and equivalents thereof.

Claims (6)

1. the Chinese medicine composition treating cough, it is characterised in that count by weight by following Chinese medicine Raw material form: Caulis Polygoni Multiflori 10-50 part, Radix Gentianae 5-30 part, Rhizoma Pinelliae 5-40 part, Arisaema balansae Engl. grass 3-30 part, Poria 5-30 part, Herba Epimedii 3-40 part, Radix Gentianae 5-35 part, Radix Zanthoxyli Spinifolii 5-30 part and Rhizoma Corydalis 5-40 Part.
Chinese medicine composition the most according to claim 1, it is characterised in that count by weight by with Lower raw material of Chinese medicine forms: Caulis Polygoni Multiflori 20-40 part, Radix Gentianae 10-20 part, Rhizoma Pinelliae 10-20 part, Arisaema balansae Engl. grass 3-20 part, Poria 5-20 part, Herba Epimedii 5-20 part, Radix Gentianae 5-25 part, Radix Zanthoxyli Spinifolii 10-20 part and Rhizoma Corydalis 10-20 part.
Chinese medicine composition the most according to claim 1, it is characterised in that count by weight by with Lower raw material of Chinese medicine form: Caulis Polygoni Multiflori 30 parts, Radix Gentianae 15 parts, the Rhizoma Pinelliae 10 parts, Arisaema balansae Engl. grass 10 parts, 10 parts of Poria, Herba Epimedii 10 parts, Radix Gentianae 10 parts, Radix Zanthoxyli Spinifolii 10 parts and Rhizoma Corydalis 10 parts.
4. a medicine, it is characterised in that including the arbitrary described Chinese medicine composition of claim 1-3 Thing and pharmaceutically acceptable adjuvant.
Medicine the most according to claim 4, it is characterised in that described is pharmaceutically acceptable auxiliary Material for starch, dextrin, lactose micropowder, silica gel, aspartame, mannitol, sodium benzoate, sucrose and At least one in Mel.
Medicine the most according to claim 4, it is characterised in that the dosage form of described medicine be decoction, Powder, granule or tablet.
CN201610193075.5A 2016-03-30 2016-03-30 Traditional Chinese medicine composition for treating coughs Pending CN105796799A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106511524A (en) * 2016-12-16 2017-03-22 天峨县全盛蜂业科技有限公司 Traditional Chinese medicine composition for treating cough
CN107812052A (en) * 2017-11-22 2018-03-20 信阳农林学院 A kind of Chinese medicine composition for treating cough

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1943675A (en) * 2006-10-26 2007-04-11 西藏藏药股份有限公司 Tibetan medicinal composition for expectorant, antitussive, antiasthmatic and its preparation method
CN101564517A (en) * 2008-04-25 2009-10-28 天津同仁堂股份有限公司 Traditional Chinese medicine for treating children cough and asthma and preparation thereof
CN104127668A (en) * 2014-07-17 2014-11-05 孟令玉 Traditional Chinese medicinal preparation for curing chronic pharyngitis
CN104258231A (en) * 2014-10-09 2015-01-07 王淑强 Traditional Chinese medicine composition for treating cough
CN104257834A (en) * 2014-10-16 2015-01-07 金化朝 Traditional Chinese medicine composition for treating cough
CN104721370A (en) * 2013-12-19 2015-06-24 青岛盛嘉信息科技有限公司 Chinese medicinal composition for treating cough

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1943675A (en) * 2006-10-26 2007-04-11 西藏藏药股份有限公司 Tibetan medicinal composition for expectorant, antitussive, antiasthmatic and its preparation method
CN101564517A (en) * 2008-04-25 2009-10-28 天津同仁堂股份有限公司 Traditional Chinese medicine for treating children cough and asthma and preparation thereof
CN104721370A (en) * 2013-12-19 2015-06-24 青岛盛嘉信息科技有限公司 Chinese medicinal composition for treating cough
CN104127668A (en) * 2014-07-17 2014-11-05 孟令玉 Traditional Chinese medicinal preparation for curing chronic pharyngitis
CN104258231A (en) * 2014-10-09 2015-01-07 王淑强 Traditional Chinese medicine composition for treating cough
CN104257834A (en) * 2014-10-16 2015-01-07 金化朝 Traditional Chinese medicine composition for treating cough

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106511524A (en) * 2016-12-16 2017-03-22 天峨县全盛蜂业科技有限公司 Traditional Chinese medicine composition for treating cough
CN107812052A (en) * 2017-11-22 2018-03-20 信阳农林学院 A kind of Chinese medicine composition for treating cough

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Application publication date: 20160727

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