CN104256167A - Functional feed for preventing and treating sheep stomatitis and preparation method thereof - Google Patents
Functional feed for preventing and treating sheep stomatitis and preparation method thereof Download PDFInfo
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- CN104256167A CN104256167A CN201410504273.XA CN201410504273A CN104256167A CN 104256167 A CN104256167 A CN 104256167A CN 201410504273 A CN201410504273 A CN 201410504273A CN 104256167 A CN104256167 A CN 104256167A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Abstract
The invention discloses a functional feed for preventing and treating sheep stomatitis and a preparation method thereof. The feed comprises the following raw materials: corn, sorghum, sweet potato, potato, mung bean, eggplant, wheat bran, watermelon peel, bitter gourd, lotus leaf, swimming bladder, ginger, wheat, bean pulp, vitamin premix, and microelement premix. The functional feed contains traditional Chinese medicine additives capable of clearing heat, removing toxicity, eliminating sore and relieving pain, and is capable of diminishing inflammation, sterilizing, resisting virus, healing skin and external diseases, preventing infection, controlling state of an illness and enhancing the immunity of sheep; furthermore, the feed is also low in drug residue, has small possibility of generating drug resistance, adopts well selected traditional Chinese medicinal materials, is low in cost and convenient to dose.
Description
Technical field
The present invention relates to technical field of animal, particularly a kind of functional feed for preventing and treating sheep stomatitis and preparation method thereof.
Background technology
Sheep stomatitis is the inflammation of mucous membrane of mouth top layer and deep tissues.In pathologic process, mucous membrane of mouth and gingival inflammation, disease sheep can be made to search for food and bradymassesis, and watery saliva flowing from the mouth, sensitivity to pain increases.Clinical common pure local inflammation and Secondary cases general reaction.
The cause of disease: primary stomatitis is many to be caused by wound, sheep can because searching for food plant branch sharp-pointed, stalk stabs oral cavity and falls ill, also can because of contact ammoniacal liquor, strong acid, highly basic, lesion ports mucous membrane and falling ill.When sheep suffers from aphtha, aftosa, sheep pox mycodermatitis, also stomatitis symptom can be there is.
Chinese veterinarian thinks that sheep stomatitis belongs to the one of " sore ", the paathogenic factor of sore, has diseases caused by external factors (the diseases caused by external factors six external factors which cause diseases evil poison, experience special poison, external injury etc.) and internal injury (feelings will internal injury, eating and drinking without temperance, chamber damage etc.) two large classes.The sore that outer heresy causes, the most common with " heat poison ", " fire poison ", the sore that chill summer-heat and damp etc. causes, have in the initial phase, and not all there is the red heat phenomenon of heat poison, fire poison, in out of contior situation, sick to mid-term, just can manifest.This kind of sore generally all has the feature of yang syndrome sore, because after sore generation, pathologic process is development and change, and the final performance of sore, be mostly heat poison, malicious the resembling of fire.More the sore that internal injury causes, mostly because void is caused a disease, and belong to chronic, as network sky of suffering from a deficiency of the kidney, easily form the tuberculosis of bone and joint for the turbid invasion and attack of chill phlegm; Deficiency of YIN of both the lung and kidney, flaring up of deficient fire, bright Tianjin is the feature first, mid-term with cloudy card sore that phlegm forms this kind of sore of scrofula more.The sore no matter that a kind of paathogenic factor causes, all can cause local and a series of pathological reaction of whole body.
Doctor trained in Western medicine control sheep stomatitis clinical treatment is longer for the course for the treatment of, clinical therapeutic efficacy is not satisfactory, prolonged application antibiotic easily produces drug resistance, and there is no pre-aseptic effect, occur more toxic and side effect, such as haematological toxicity reaction, liver renal toxicity reacts, gastrointestinal reactions etc., the in a short time wayward state of an illness, can delay treatment etc.
But traditional Chinese medicine prevention sheep stomatitis, not only can make up the deficiency of doctor trained in Western medicine, can anti-inflammation and sterilization antiviral, healing sore, prevention is infected, symptom management, strengthens the immunity of sheep, and low medicament residue, not easily produces drug resistance.Selected Chinese medicinal material, cost price is cheap, convenient drug administration, is applicable to carrying out marketing.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of feed comprising Chinese medicine additive for preventing and treating sheep stomatitis, adopt the feed containing this Chinese medicine additive can overcome the defect of prior art Chinese and Western medicine and Chinese medicine, treatment sheep stomatitis, clearing heat and detoxicating, the sore that disappears pain relieving, can anti-inflammation and sterilization antiviral, healing sore, prevention infect, symptom management, strengthen the immunity of sheep, and low medicament residue, not easily produce drug resistance; Selected Chinese medicinal material, cost price is cheap, convenient drug administration.
In order to realize foregoing invention object, the invention provides a kind of functional feed for preventing and treating sheep stomatitis, described feed comprises following raw material: corn, Chinese sorghum, Ipomoea batatas, potato, mung bean, eggplant, wheat bran, watermelon peel, balsam pear, lotus leaf, air bladder, ginger, wheat, dregs of beans, vitamin premix and microelement pre-mix material.In described feed, the parts by weight of each raw material are: corn 20-40 weight portion, Chinese sorghum 30-60 weight portion, Ipomoea batatas 15-20 weight portion, potato 15-30 weight portion, mung bean 10-16 weight portion, eggplant 13-28 weight portion, wheat bran 7-15 weight portion, watermelon peel 10-19 weight portion, balsam pear 17-30 weight portion, lotus leaf 10-20 weight portion, air bladder 5-13 weight portion, ginger 10-14 weight portion, wheat 2-5 weight portion, dregs of beans 2-5 weight portion, vitamin premix 0.1-0.5 weight portion and microelement pre-mix material 0.1-0.5 weight portion.
Described feed also comprises Chinese medicine additive, in described feed, the parts by weight of each raw material are: corn 20-40 weight portion, Chinese sorghum 30-60 weight portion, Ipomoea batatas 15-20 weight portion, potato 15-30 weight portion, mung bean 10-16 weight portion, eggplant 13-28 weight portion, wheat bran 7-15 weight portion, watermelon peel 10-19 weight portion, balsam pear 17-30 weight portion, lotus leaf 10-20 weight portion, air bladder 5-13 weight portion, ginger 10-14 weight portion, wheat 2-5 weight portion, dregs of beans 2-5 weight portion, vitamin premix 0.1-0.5 weight portion, microelement pre-mix material 0.1-0.5 weight portion and Chinese medicine additive 3-5 weight portion.
In described feed, the parts by weight of each raw material are: corn 27 weight portion, Chinese sorghum 53 weight portion, Ipomoea batatas 17 weight portion, potato 23 weight portion, mung bean 15 weight portion, eggplant 22 weight portion, wheat bran 9 weight portion, watermelon peel 17 weight portion, balsam pear 29 weight portion, lotus leaf 14 weight portion, air bladder 8 weight portion, ginger 12 weight portion, wheat 4 weight portion, dregs of beans 3 weight portion, vitamin premix 0.3 weight portion, microelement pre-mix material 0.3 weight portion and Chinese medicine additive 4 weight portion.
Described Chinese medicine additive comprises following raw medicinal material: honeysuckle, the capsule of weeping forsythia, Herba Andrographitis, folium isatidis, indigo naturalis, dandelion, Chinese violet, mother chrysanthemum, smilax, cordate houttuynia, rattletop, root of Chinese trichosanthes, Asian puccoon, lophatherum gracile, golden cypress, the root bark of shaggy-fruited dittany, manyleaf meadowure rhizome and root, setose thistle, field thistle, garden burnet, radix boehmeriae, cow-bezoar, pearl, the pig iron fall, borneol, freyn cinquefoil herb, manystem stonecrop leaf, yarrow, certainly to disappear Rong, Ke rattan and sunset abelmoschus root.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are: honeysuckle 21-36 weight portion, capsule of weeping forsythia 10-25 weight portion, Herba Andrographitis 13-26 weight portion, folium isatidis 23-35 weight portion, indigo naturalis 14-24 weight portion, dandelion 17-34 weight portion, Chinese violet 20-34 weight portion, mother chrysanthemum 21-32 weight portion, smilax 16-28 weight portion, cordate houttuynia 13-27 weight portion, rattletop 23-35 weight portion, root of Chinese trichosanthes 25-39 weight portion, Asian puccoon 14-30 weight portion, lophatherum gracile 20-33 weight portion, golden cypress 13-27 weight portion, root bark of shaggy-fruited dittany 17-29 weight portion, manyleaf meadowure rhizome and root 8-19 weight portion, setose thistle 21-37 weight portion, field thistle 16-30 weight portion, garden burnet 12-26 weight portion, radix boehmeriae 14-33 weight portion, cow-bezoar 21-36 weight portion, pearl 24-38 weight portion, the pig iron falls 17-37 weight portion, borneol 5-13 weight portion, freyn cinquefoil herb 17-31 weight portion, manystem stonecrop leaf 13-28 weight portion, yarrow 10-25 weight portion, 4-10 weight portion is held from disappearing, Ke rattan 3-8 weight portion and sunset abelmoschus root 16-27 weight portion.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are: honeysuckle 23 weight portion, the capsule of weeping forsythia 15 weight portion, Herba Andrographitis 16 weight portion, folium isatidis 27 weight portion, indigo naturalis 17 weight portion, dandelion 23 weight portion, Chinese violet 31 weight portion, mother chrysanthemum 29 weight portion, smilax 18 weight portion, cordate houttuynia 18 weight portion, rattletop 32 weight portion, root of Chinese trichosanthes 35 weight portion, Asian puccoon 16 weight portion, lophatherum gracile 30 weight portion, golden cypress 23 weight portion, the root bark of shaggy-fruited dittany 17 weight portion, manyleaf meadowure rhizome and root 11 weight portion, setose thistle 24 weight portion, field thistle 26 weight portion, garden burnet 14 weight portion, radix boehmeriae 28 weight portion, cow-bezoar 23 weight portion, pearl 31 weight portion, the pig iron falls 17 weight portions, borneol 11 weight portion, freyn cinquefoil herb 17 weight portion, manystem stonecrop leaf 25 weight portion, yarrow 10 weight portion, from appearance 8 weight portion that disappears, Ke rattan 3 weight portion and sunset abelmoschus root 18 weight portion.
The preparation method of described Chinese medicine additive comprises the following steps:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 4 ~ 8 times, mixture is the ethanol of 85% ~ 95%, be heated to boiling reflux 3 ~ 5 hours, filter, adopt percolation with the speed of 1 ~ 2ml per minute slowly diacolation, collect percolate, when being evaporated to 50 ~ 60 DEG C subsequently under vacuum 0.06 ~ 0.09Mpa, relative density is the lotion of 1.04 ~ 1.10, spraying dry, the EAT 160 ~ 175 DEG C of spray dryer, leaving air temp 80 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder;
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.2 ~ 0.4 times and 0.1 ~ 0.2 times in the dried cream powder obtained, makes particle, in 40 ~ 50 DEG C of dryings, obtains granule.
In order to better realize foregoing invention object, the invention provides a kind of preparation method of the functional feed for preventing and treating sheep stomatitis, it is characterized in that, described preparation method comprises the following steps:
The first step, corn, Chinese sorghum, Ipomoea batatas, potato, mung bean, eggplant, wheat bran, watermelon peel, balsam pear, lotus leaf, air bladder, ginger, wheat and dregs of beans mix by ratio by weight, put in pulverizer and pulverize, and cross 2.0mm sieve after pulverizing;
Second step, takes vitamin premix, microelement pre-mix material and Chinese medicine additive according to ratio of weight and number, pulverizes the fine powder obtained mix with step (1), and drop into mixer, mix, incorporation time is 30-60s;
3rd step, drop into granulator and granulate, pelleting temperature is 85 DEG C, makes its gelatinization degree reach more than 90%.
The beneficial effect that the technical scheme that the embodiment of the present invention provides is brought is: feed of the present invention contains Chinese medicine additive treatment sheep stomatitis, with clearing heat and detoxicating, the sore that disappears pain relieving master, treatment sheep stomatitis can anti-inflammation and sterilization antiviral, healing sore, prevention is infected, symptom management, strengthen the immunity of sheep, and low medicament residue, not easily produce drug resistance; Selected Chinese medicinal material, cost price is cheap, convenient drug administration.
Detailed description of the invention
Chinese veterinarian thinks, controls and controls outward, the two normal connected applications in the treatment of sore divides.Large, critical sore disease, as septicemia, caves in, controls, controls combination outward in not only needing.The general provisions of sore internal therapy are for disappearing, holding in the palm, mend.When initial stage not yet becomes purulence, make it to dissipate with elimination, and use clearing heat and detoxicating and battalion's row stasis of blood, promoting the circulation of qi for the cause of disease, the state of an illness, induce sweat, the rule such as Wen Tong, Tongli, reason are wet, wherein clearing heat and detoxicating is the most frequently used therapy of sore; Mid-term, purulence became not burst or purulence goes out smooth, and go out to hold in the palm poison by holder method, Tuo Fa divides again promoting pus-drainage by orally taking medicine and therapy of dispersion by invigorating; Later stage deficiency of vial QI person, recovers healthy tendency by reinforcing method, and the open sore part is healed early, usual useful gas, nourish blood, enriching yin, the rule such as supporing yang.According to whole body and local circumstance, by the change and progress of the state of an illness, principal contradiction should be caught, establishment of the therapeutic methods and Applying Medicine when specifically treating.Sore external therapy should, intermediary and later stages respectively diagnosis and prescription first according to sore.
Therefore, for the corresponding symptom that ill sheep occurs, the invention provides a kind of with heat-clearing solution, the sore that disappears pain relieving is primary treatment principle, provide a kind of feed for preventing and treating sheep stomatitis, it comprises Chinese medicine additive, Chinese medicine additive comprises following raw medicinal material:: honeysuckle, the capsule of weeping forsythia, Herba Andrographitis, folium isatidis, indigo naturalis, dandelion, Chinese violet, mother chrysanthemum, smilax, cordate houttuynia, rattletop, root of Chinese trichosanthes, Asian puccoon, lophatherum gracile, golden cypress, the root bark of shaggy-fruited dittany, manyleaf meadowure rhizome and root, setose thistle, field thistle, garden burnet, radix boehmeriae, cow-bezoar, pearl, the pig iron falls, borneol, freyn cinquefoil herb, manystem stonecrop leaf, yarrow, from the appearance that disappears, Ke rattan and sunset abelmoschus root.
Wherein, honeysuckle, the capsule of weeping forsythia, Herba Andrographitis, folium isatidis, indigo naturalis, dandelion, Chinese violet, mother chrysanthemum, smilax, cordate houttuynia, rattletop, root of Chinese trichosanthes, Asian puccoon, lophatherum gracile, freyn cinquefoil herb, manystem stonecrop leaf, yarrow and certainly disappear appearance clearing heat-fire, removing toxic substances, loose carbuncle detumescence; Golden cypress, the root bark of shaggy-fruited dittany, manyleaf meadowure rhizome and root heat-clearing and damp-drying drug, purging intense heat and detonicating of holding concurrently; Setose thistle, field thistle, garden burnet, sheep hoof, radix boehmeriae cooling blood and hemostasis, removing toxic substances sore; Cow-bezoar, pearl, the pig iron fall, borneol is clearing heat and detoxicating, regenerating tissue to heal wond; Ke rattan and sunset abelmoschus root pain relieving; Full side's compatibility science, rigorous, can anti-inflammation and sterilization antiviral, healing sore, prevention is infected, symptom management, strengthens the immunity etc. of sheep.
The pharmacology of each bulk drug is as follows:
Honeysuckle: cold in nature, taste is sweet, enters lung, the heart, stomach warp.There is effect that clearing heat and detoxicating, anti-inflammatory, qi-restoratives treat wind, cure mainly disease under turgor, warm disease heating, the diseases such as hot malicious large carbuncle and tumour.
The capsule of weeping forsythia: bitter, cold nature; Enter the heart, lung, small intestinl channel.The pharmacological action such as have antibacterial, cardiac stimulant, diuresis, town to tell is clearing heat and detoxicating Chinese medicine, cure mainly pyreticosis from the beginning of, anemopyretic cold, heating, vexed, the symptom such as abscess of throat, acute nephritis, carbuncle sore tumefacting virus.
Herba Andrographitis: bitter, cold.The thoughts of returning home, lung, large intestine, urinary bladder channel.There are clearing heat and detoxicating, anti-inflammatory, swelling and pain relieving effect.Cure mainly bacillary dysentery, urinary tract infections, acute tonsillitis, enteritis, sphagitis, pneumonia and influenza etc., external application can treat sore furuncle poison, trauma infection contamination etc.
Folium isatidis: bitter, cold; Enter liver, the heart, stomach warp.Control the hot poison of pestilence to go mad, wind-heat macula, large carbuncle swells and ache, relieving thirst and restlessness, only nosebleed epistaxis, haematemesis, kills infantile malnutrition due to digestive disturbances or intestinalparasites erosion, metal-inflicted wound curare.Heat-clearing, removing toxic substances, cool blood, hemostasis.Control warm disease heat and contain polydipsia, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas, spit blood, bleeding from five sense organs or subcutaneous tissue, jaundice, dysentery, larynx numbness, aphtha, swollen ulcer drug.
Indigo naturalis: taste is salty, cold in nature, enter Liver Channel.There is effect of clearing heat and detoxicating, cooling blood and hemostasis, clearing liver-fire, send out spot for warm disease, haematemesis, abscess of throat, bleb wet the malicious all cards of heat such as sore, liver-fire attacking lung, cough pectoralgia, blood-stained sputum, the frightened card such as epilepsy, convulsion of high heat.
Dandelion: nature and flavor are sweet, micro-hardship, cold, enter spleen, stomach, kidney three warp.Clearing heat and detoxicating, the carbuncle that disappears dissipating bind.Can be used for the infection of the upper respiratory tract, eye conjunctivitis, mumps, hyperglycaemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, cholecystitis, acute appendicitis, urinary infection, pelvic infecton, carbuncle furuncle furunculosis, pharyngitis, controls acute mastitis, adenolymphitis, scrofula, malignant boil carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infections.
Chinese violet: bitter, pungent, cold in nature, enters the heart, Liver Channel.There is the effect of clearing heat and detoxicating, cool blood detumescence, main influenza; The infection of the upper respiratory tract; Tonsillitis; Catarrhal jaundice; Enteritis; Dysentery; Ephritis; Mumps; Conjunctivitis; Acute appendicitis; Furunculosis carbuncle swells; Scrofula.Clearing heat and detoxicating.Control furunculosis carbuncle to swell, heat in jaundice, children's's nosebleed, appendicitis, venomous snake bite.
Mother chrysanthemum: cold nature, bitter, pungent, return liver, the heart channel of Hang-Shaoyin.Function is clearing heat and detoxicating, detumescence.To staphylococcus aureus, corynebacterium diphtheriae, streptococcus, Pseudomonas aeruginosa, puncture Shigella, influenza virus, all there is inhibitory action.To furunculosis, ulcer, erysipelas, eczema, dermatitis, anemopyretic cold, abscess of throat, high blood pressure etc. have good curative effect.
Smilax: taste is sweet, light, property is put down, poisonous; Enter liver, stomach, kidney, the spleen channel.Removing toxic substances, dehumidifying, sharp joint.Cure mainly syphilis, stranguria with turbid discharge, muscles and bones contraction pain, beriberi, treats furunculosis, and carbuncle swells, scrofula, syphilis and the limbs contraction caused by mercury poisoning, arthralgia and myalgia.
Cordate houttuynia: cold nature, bitter, returns lung channel, bladder, large intestine channel.Clearing heat and detoxicating, inducing diuresis to reduce edema.Control pneumonia, lung abscess, hot dysentery, malaria, oedema, gonorrhoea, leukorrhea, carbuncle swells, hemorrhoid, prolapse of the anus, eczema, the favus of the scalp, mange.
Rattletop: taste is pungent, sweet, cold nature; Return lung channel, the spleen channel, large intestine channel, stomach warp.Function is clearing heat and detoxicating, promoting eruption.Thoroughly send out smooth, maculopapulae due to toxic heat, diseases caused by external factors illness that has not attacked the vital organs of the human body for measles, weigh under epidemic disease fire poison, aphtha, pharyngalgia, headache fever and chills, carbuncle sore tumefacting virus, the sinking of qi of middle-jiao, splenasthenic diarrhea, protracted dysentery, women is with down, metrorrhagia.
Root of Chinese trichosanthes: sweet, micro-hardship, is slightly cold; Attach to the lung and stomach meridians.Clearing heat and promoting fluid, detumescence and apocenosis.
Asian puccoon: cold in nature, taste is sweet, salty, the thoughts of returning home, Liver Channel.Be mainly used in that blood-head poison is contained, macula purple black, measles without adequate eruption, sore, eczema, scald etc.
Lophatherum gracile: nature and flavor, sweet, be slightly cold.The thoughts of returning home, stomach, small intestinl channel.Clearing heat and relieving fidgetness, diuresis.For pyreticosis polydipsia, hot urination drenches pain, aphthae.
Golden cypress: bitter, cold.Return kidney, urinary bladder channel.Heat-clearing and damp-drying drug, purging intense heat removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice, under band, heat is drenched, beriberi, and impotence { is warded off }, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, eczema itch.Stir-baked CORTEX PHELLODENDRI with salt solution is nourishing Yin and falling fire.For fire excess from yin deficiency, night sweat hectic fever due to yin.
The root bark of shaggy-fruited dittany: bitter, salty, cold; Enter the spleen channel, lung channel, small intestinl channel, stomach warp, urinary bladder channel.Control all hot malicious wind, dislike wind, wind sore, mange are red rotten, and it is crisp that eyebrow is sent out de-, and musculus cutaneus is anxious, high fever aversion to cold; Principal solution heat is yellow, wine is yellow, acute febrile, paddy Huang, labor are yellow.
Manyleaf meadowure rhizome and root: bitter; Cold in nature; The thoughts of returning home, liver, large intestine channel.Heat-clearing and damp-drying drug; Purging intense heat and detonicating.Cure mainly damp-heat dysentery; Jaundice; Sore swollen toxin; Red eye, swell pain; Cold, fever; Cancerous swelling.
Setose thistle: cool in nature, taste is sweet, bitter, nontoxic, the thoughts of returning home, Liver Channel.Cooling blood and hemostasis, removing toxicity for eliminating carbuncles.Control haematemesis, bleeding from five sense organs or subcutaneous tissue, hematuria, blood drenches, metrorrhagia, under band, and intestines wind, acute appendicitis, large carbuncle pyogenic infections, furunculosis.
Field thistle: sweet, bitter, cold, the thoughts of returning home, Liver Channel.Function cooling blood and hemostasis, eliminating stasis to resolve swelling.For bleeding from five sense organs or subcutaneous tissue, spit blood, hematuria, has blood in stool, metrostaxis, traumatism and bleeding, carbuncle sore tumefacting virus.
Garden burnet: picric acid, cold, nontoxic; Return liver, lung, kidney, large intestine channel.Function cooling blood and hemostasis, clearing heat and detoxicating, detumescence sore.For spitting blood, spitting of blood, bleeding from five sense organs or subcutaneous tissue, hematuria, has blood in stool, hemorrhoid blood, bloody flux, uterine bleeding, leukorrhea with reddish discharge, sore, carbuncle and painful swelling, eczema, pruritus vulvae, scald, snake bite and insect sting.
Radix boehmeriae: taste is sweet is sliding, cold, nontoxic; Enter lung, the spleen channel.Function heat-clearing, hemostasis, removing toxic substances, the loose stasis of blood.Control pyreticosis large yearningly, mad greatly, blood drenches, the retention of urine, spits blood, lower blood, leukorrhea with reddish discharge, erysipelas, and carbuncle swells, traumatic injury, snake bite and insect sting.
Cow-bezoar: bitter, cool; The thoughts of returning home, Liver Channel.Clear away heart-fire, slit phlegm, has one's ideas straightened out, cool liver, breath wind, removing toxic substances.For pyreticosis coma, apoplexy phlegm fan, frightened epilepsy is twitched, and epilepsy is gone mad, abscess of throat, aphthae, and carbuncle swells furunculosis.
Pearl: sweet, salty, cold.The thoughts of returning home, Liver Channel.Calm the nerves arresting convulsion, improving eyesight disappears screen, detoxify and promote granulation.For insomnia of palpitating with fear, infantile convulsion epilepsy, the raw cloudiness of order, sore is not held back.
The pig iron falls: pungent; Cool; The thoughts of returning home; Liver Channel.Checking hyperfunction of the liver and relieving convulsion; Removing toxic substances sore; Enrich blood.Main demented; Febrile delirium; Palpitation and being susceptible to fright; Arthralgia due to wind-dampness; Anaemia; Sore swollen toxin.
Borneol: arduous, cool; Enter the heart, lung channel.Logical all keys, loose stagnated fire, goes screen improving eyesight, swelling and pain relieving.Control middle air port to keep silent, pyreticosis coma, frightened epilepsy phlegm fan, deafness with qi stagnation, larynx numbness, aphtha, tympanitis, carbuncle swells, and hemorrhoid, order is screen film also, enterobiasis.
Freyn cinquefoil herb: bitter, is slightly cold.Clearing heat and detoxicating, loose stasis of blood hemostasis.Control bone tuberculosis, stomatitis, scrofula, traumatic injury, traumatism and bleeding.
Manystem stonecrop leaf: cold nature, taste is sweet micro-pungent.Clearing heat and detoxicating, hemostasis, wines used as antirheumatic.Control abscess of throat, nosebleed epistaxis, wind-heat is dizzy, rheumatic arthritis, nasal eczema, eczema, sore.
Yarrow: sweetness and bitterness is pungent, cold in nature.Clearing heat and detoxicating, regulating menstruation by adjusting the flow of blood.Control carbuncle furuncle poison, traumatic injury, hemorrhoid hemorrhage, irregular menstruation.
From the appearance that disappears: light; Cold.Return lung; The spleen channel.Clearing heat and detoxicating, cooling blood and hemostasis, inducing diuresis for removing edema.Main children's's head sore, aphtha, toothache, cough with lung heat spits blood, traumatic injury, traumatism and bleeding, oedema, kidney stone, cystitis, treating rheumatic ostealgia.
Ke rattan: bitter; Puckery; Flat.Return kidney channel.Dispel rheumatism; Promoting blood circulation and removing obstruction in channels.Main air pain of dampness syndrome; Traumatic injury; Lumbar muscle strain; Numb limb.
Sunset abelmoschus root: sweet, cold, sliding, nontoxic.Return lung; Kidney; Urinary bladder channel.Li Shui, the loose stasis of blood, detumescence, removing toxic substances.Control gonorrhoea, oedema, alactation, mumps, carbuncle swells.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese medicine additive
Extracting honeysuckle 23 weight portion, the capsule of weeping forsythia 15 weight portion, Herba Andrographitis 16 weight portion, folium isatidis 27 weight portion, indigo naturalis 17 weight portion, dandelion 23 weight portion, Chinese violet 31 weight portion, mother chrysanthemum 29 weight portion, smilax 18 weight portion, cordate houttuynia 18 weight portion, rattletop 32 weight portion, root of Chinese trichosanthes 35 weight portion, Asian puccoon 16 weight portion, lophatherum gracile 30 weight portion, golden cypress 23 weight portion, the root bark of shaggy-fruited dittany 17 weight portion, manyleaf meadowure rhizome and root 11 weight portion, setose thistle 24 weight portion, field thistle 26 weight portion, garden burnet 14 weight portion, radix boehmeriae 28 weight portion, cow-bezoar 23 weight portion, pearl 31 weight portion, the pig iron falls 17 weight portions, borneol 11 weight portion, freyn cinquefoil herb 17 weight portion, manystem stonecrop leaf 25 weight portion, yarrow 10 weight portion, from appearance 8 weight portion that disappears, Ke rattan 3 weight portion and sunset abelmoschus root 18 weight portion.
Preparation method comprises the following steps:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 5 times, mixture is the ethanol of 95%, be heated to boiling reflux 5 hours, filter, adopt percolation with the speed of 2ml per minute slowly diacolation, collect percolate, when being evaporated to 60 DEG C subsequently under vacuum 0.09Mpa, relative density is the lotion of 1.10, spraying dry, the EAT 175 DEG C of spray dryer, leaving air temp 85 DEG C, be ground into powder subsequently, make dried cream powder;
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.3 times and 0.1 times in the dried cream powder obtained, makes particle, in 50 DEG C of dryings, obtains granule.
Embodiment 2 feed
Embodiments provide a kind of functional feed for preventing and treating sheep stomatitis, in feed, the parts by weight of each raw material are: corn 27 weight portion, Chinese sorghum 53 weight portion, Ipomoea batatas 17 weight portion, potato 23 weight portion, mung bean 15 weight portion, eggplant 22 weight portion, wheat bran 9 weight portion, watermelon peel 17 weight portion, balsam pear 29 weight portion, lotus leaf 14 weight portion, air bladder 8 weight portion, ginger 12 weight portion, wheat 4 weight portion, dregs of beans 3 weight portion, vitamin premix 0.3 weight portion, microelement pre-mix material 0.3 weight portion and Chinese medicine additive 4 weight portion; Wherein Chinese medicine additive is the Chinese medicine interpolation granule of embodiment 1.
Its preparation method comprises the following steps:
The first step, corn, Chinese sorghum, Ipomoea batatas, potato, mung bean, eggplant, wheat bran, watermelon peel, balsam pear, lotus leaf, air bladder, ginger, wheat and dregs of beans mix by ratio by weight, put in pulverizer and pulverize, and cross 2.0mm sieve after pulverizing;
Second step, takes vitamin premix, microelement pre-mix material and Chinese medicine additive according to ratio of weight and number, pulverizes the fine powder obtained mix with step (1), and drop into mixer, mix, incorporation time is 30-60s;
3rd step, drop into granulator and granulate, pelleting temperature is 85 DEG C, makes its gelatinization degree reach more than 90%.
The toxicity test of Chinese medicine additive
Extracting honeysuckle 23g, capsule of weeping forsythia 15g, Herba Andrographitis 16g, folium isatidis 27g, indigo naturalis 17g, dandelion 23g, Chinese violet 31g, mother chrysanthemum 29g, smilax 18g, cordate houttuynia 18g, rattletop 32g, root of Chinese trichosanthes 35g, Asian puccoon 16g, lophatherum gracile 30g, golden cypress 23g, root bark of shaggy-fruited dittany 17g, manyleaf meadowure rhizome and root 11g, setose thistle 24g, field thistle 26g, garden burnet 14g, radix boehmeriae 28g, cow-bezoar 23g, pearl 31g, the pig iron falls 17g, borneol 11g, freyn cinquefoil herb 17g, manystem stonecrop leaf 25g, yarrow 10g, 8g is held from disappearing, Ke rattan 3g and sunset abelmoschus root 18g, after mixing, pulverize, in the mixture after pulverizing, add the water of 1200g, decoct 2.5 hours, filter, the water adding 500g in filter residue decocts 1.5 hours again, filters, and by twice filtrate mixing, is evaporated to the decoction that crude drug concentration is 3g/ml.
Select SD rat, give the decoction of the Chinese medicine additive of the present invention of variable concentrations (18.0,6.0,2.0g crude drug/kg), every day gavage once, continuous 90 days, within after last administration 24 hours, respectively group is alive kills 1/2 animal (male and female half and half), and all the other 1/2 animals continue observations 2 weeks rear living and kill.Duration of test observes outward appearance, general behavior, food ration, the changes of weight of animal, within after administration 90 days, within 2 weeks, carries out the index checking such as hematology (RBC, HB, granulophilocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crca, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, Histopathology with drug withdrawal.Result of the test shows: Chinese medicine additive of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three dosage groups and control group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range (NR), without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, rat is had no significant effect in high, medium and low three dosage (18.0,6.0,2.0g crude drug/kg) administration in continuous 90 days according to result of the test Chinese medicine preparation of the present invention, without clear and definite toxicity target organ and sensitive indicator, convalescence observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention higher.
Contrast test
(1) for examination animal
Choose 3, Liuzhou goat plant make a definite diagnosis after sick sheep in random selecting 120 sick sheep as treatment contrast test object; Another from the plant of other anosis goats of Liuzhou random selecting 120 health 1 monthly age lambs as prevention contrast test object.
(2) pathological material of disease extracts
Get the adult goat oral mucous epithelia of 4 natural occurrence 1-2 days.Before taking pathological material of disease, first wipe cleaning with the cotton that sterile saline is dipped and urge disease oral cavity for several times, then hold sharp sword that scalding crosses and take the photograph son epithelium of tearing and move in people 50% sterile glycerol salt solution, save backup.Face the used time, claim its weight, add sterile saline make suspension in 1:20 ratio, every milliliter outstanding shakes in liquid, adds penicillin 2D00 unit and streptomysin 1000 unit, for subsequent use 4-10 DEG C of left at room temperature 4 hours.
(3) contrast experiment is prevented:
120 of random choose healthy lambs are divided at random 3 groups (control group 1, control group 2 and embodiment groups), wherein, control group 1 and control group 2 use traditional sheep feed to feed sheep, embodiment group uses the feed in embodiment 2 to feed sheep 4 days, control group 1 and embodiment group are got to the pathological material of disease suspension of goat, mucous membrane scratch inoculation in lamb lip, observed and recorded respectively organizes the incidence of disease of sheep, and result is as shown in table 1.
The table 1 preventive effect table of comparisons
Data from table 1: the feed that the present invention contains Chinese medicine additive has obvious preventive effect to sheep stomatitis.
(4) contrast test is treated:
Curative effect determinate standard
Cure: suffer from sheep after the treatment of 1 week, its Oral symptoms disappears, and can normally take food, temperature recovery is normal.
Effective: the Oral symptoms of suffering from sheep disappears substantially, food-intake compares increase with before treatment, and temperature recovery is normal.
Invalid: suffer from sheep after the treatment of 1 week, its Oral symptoms still exists, and body temperature is higher, and food-intake is without increase.
Be divided at random by 120 of random selecting sick sheep 3 groups (treatment by Chinese herbs group, western medicine group, blank groups), treat with different medicine, wherein, treatment by Chinese herbs group selects the Chinese medicine additive 1 of embodiment 1, and dose is 0.6g/kg every day, takes 4 days continuously; 25 tablets of metronidazoles of every sheet net weight 0.2g are ground into powder by western medicine group, be mixed in 30ml warm water and stir, finally add 70ml glycerine and be hybridly prepared into the metronidazole glycerine mixture that concentration is 0.5%, after first rinsing disease sheep oral cavity with concentration 0.2% potassium permanganate, metronidazole glycerine mixture is embrocated at its affected part, every day each 1 time sooner or later, continuous use 7 days; Blank group does not feed any medicine.Observed and recorded respectively organizes cure rate and the healing time of sheep, and result is as shown in table 2.
The table 2 result for the treatment of table of comparisons
Data from table 2: Chinese medicine additive of the present invention is obviously better than western medicine group to sheep stomatitis result for the treatment of, improve cure rate.
Model case:
Choose the sick sheep 70 that veterinary station accepts for medical treatment, be diagnosed as sheep stomatitis.Illness shows as poor appetite, salivation in mouth, and chew slowly, body temperature is elevated to about 40 DEG C, and mucous membrane swelling appears in the sick sheep cavity interior of part, and with exedens focus.
Choose 30 ill sheep wherein, the feed of the present embodiment 2 that starts to feed is fed sheep, and feed 2 days, sick sheep is clearly better, and continues to feed 1 day, sick sheep recovery from illness.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (9)
1. one kind for preventing and treating the functional feed of sheep stomatitis, it is characterized in that, described feed comprises following raw material: corn, Chinese sorghum, Ipomoea batatas, potato, mung bean, eggplant, wheat bran, watermelon peel, balsam pear, lotus leaf, air bladder, ginger, wheat, dregs of beans, vitamin premix and microelement pre-mix material.
2. the functional feed for preventing and treating sheep stomatitis according to claim 1, it is characterized in that, in described feed, the parts by weight of each raw material are: corn 20-40 weight portion, Chinese sorghum 30-60 weight portion, Ipomoea batatas 15-20 weight portion, potato 15-30 weight portion, mung bean 10-16 weight portion, eggplant 13-28 weight portion, wheat bran 7-15 weight portion, watermelon peel 10-19 weight portion, balsam pear 17-30 weight portion, lotus leaf 10-20 weight portion, air bladder 5-13 weight portion, ginger 10-14 weight portion, wheat 2-5 weight portion, dregs of beans 2-5 weight portion, vitamin premix 0.1-0.5 weight portion and microelement pre-mix material 0.1-0.5 weight portion.
3. the functional feed for preventing and treating sheep stomatitis according to claim 1 and 2, it is characterized in that, described feed also comprises Chinese medicine additive, in described feed, the parts by weight of each raw material are: corn 20-40 weight portion, Chinese sorghum 30-60 weight portion, Ipomoea batatas 15-20 weight portion, potato 15-30 weight portion, mung bean 10-16 weight portion, eggplant 13-28 weight portion, wheat bran 7-15 weight portion, watermelon peel 10-19 weight portion, balsam pear 17-30 weight portion, lotus leaf 10-20 weight portion, air bladder 5-13 weight portion, ginger 10-14 weight portion, wheat 2-5 weight portion, dregs of beans 2-5 weight portion, vitamin premix 0.1-0.5 weight portion, microelement pre-mix material 0.1-0.5 weight portion and Chinese medicine additive 3-5 weight portion.
4. the functional feed for preventing and treating sheep stomatitis according to any one of claim 1-3, it is characterized in that, in described feed, the parts by weight of each raw material are: corn 27 weight portion, Chinese sorghum 53 weight portion, Ipomoea batatas 17 weight portion, potato 23 weight portion, mung bean 15 weight portion, eggplant 22 weight portion, wheat bran 9 weight portion, watermelon peel 17 weight portion, balsam pear 29 weight portion, lotus leaf 14 weight portion, air bladder 8 weight portion, ginger 12 weight portion, wheat 4 weight portion, dregs of beans 3 weight portion, vitamin premix 0.3 weight portion, microelement pre-mix material 0.3 weight portion and Chinese medicine additive 4 weight portion.
5. the functional feed for preventing and treating sheep stomatitis according to any one of claim 1-4; it is characterized in that, described Chinese medicine additive comprises following raw medicinal material: honeysuckle, the capsule of weeping forsythia, Herba Andrographitis, folium isatidis, indigo naturalis, dandelion, Chinese violet, mother chrysanthemum, smilax, cordate houttuynia, rattletop, root of Chinese trichosanthes, Asian puccoon, lophatherum gracile, golden cypress, the root bark of shaggy-fruited dittany, manyleaf meadowure rhizome and root, setose thistle, field thistle, garden burnet, radix boehmeriae, cow-bezoar, pearl, the pig iron fall, borneol, freyn cinquefoil herb, manystem stonecrop leaf, yarrow, certainly to disappear Rong, Ke rattan and sunset abelmoschus root.
6. the functional feed for preventing and treating sheep stomatitis according to any one of claim 1-5, is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: honeysuckle 21-36 weight portion, capsule of weeping forsythia 10-25 weight portion, Herba Andrographitis 13-26 weight portion, folium isatidis 23-35 weight portion, indigo naturalis 14-24 weight portion, dandelion 17-34 weight portion, Chinese violet 20-34 weight portion, mother chrysanthemum 21-32 weight portion, smilax 16-28 weight portion, cordate houttuynia 13-27 weight portion, rattletop 23-35 weight portion, root of Chinese trichosanthes 25-39 weight portion, Asian puccoon 14-30 weight portion, lophatherum gracile 20-33 weight portion, golden cypress 13-27 weight portion, root bark of shaggy-fruited dittany 17-29 weight portion, manyleaf meadowure rhizome and root 8-19 weight portion, setose thistle 21-37 weight portion, field thistle 16-30 weight portion, garden burnet 12-26 weight portion, radix boehmeriae 14-33 weight portion, cow-bezoar 21-36 weight portion, pearl 24-38 weight portion, the pig iron falls 17-37 weight portion, borneol 5-13 weight portion, freyn cinquefoil herb 17-31 weight portion, manystem stonecrop leaf 13-28 weight portion, yarrow 10-25 weight portion, 4-10 weight portion is held from disappearing, Ke rattan 3-8 weight portion and sunset abelmoschus root 16-27 weight portion.
7. the functional feed for preventing and treating sheep stomatitis according to any one of claim 1-6, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: honeysuckle 23 weight portion, the capsule of weeping forsythia 15 weight portion, Herba Andrographitis 16 weight portion, folium isatidis 27 weight portion, indigo naturalis 17 weight portion, dandelion 23 weight portion, Chinese violet 31 weight portion, mother chrysanthemum 29 weight portion, smilax 18 weight portion, cordate houttuynia 18 weight portion, rattletop 32 weight portion, root of Chinese trichosanthes 35 weight portion, Asian puccoon 16 weight portion, lophatherum gracile 30 weight portion, golden cypress 23 weight portion, the root bark of shaggy-fruited dittany 17 weight portion, manyleaf meadowure rhizome and root 11 weight portion, setose thistle 24 weight portion, field thistle 26 weight portion, garden burnet 14 weight portion, radix boehmeriae 28 weight portion, cow-bezoar 23 weight portion, pearl 31 weight portion, the pig iron falls 17 weight portions, borneol 11 weight portion, freyn cinquefoil herb 17 weight portion, manystem stonecrop leaf 25 weight portion, yarrow 10 weight portion, from appearance 8 weight portion that disappears, Ke rattan 3 weight portion and sunset abelmoschus root 18 weight portion.
8. the functional feed for preventing and treating sheep stomatitis according to any one of claim 1-7, it is characterized in that, the preparation method of described Chinese medicine additive comprises the following steps:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 4 ~ 8 times, mixture is the ethanol of 85% ~ 95%, be heated to boiling reflux 3 ~ 5 hours, filter, adopt percolation with the speed of 1 ~ 2ml per minute slowly diacolation, collect percolate, when being evaporated to 50 ~ 60 DEG C subsequently under vacuum 0.06 ~ 0.09Mpa, relative density is the lotion of 1.04 ~ 1.10, spraying dry, the EAT 160 ~ 175 DEG C of spray dryer, leaving air temp 80 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder;
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.2 ~ 0.4 times and 0.1 ~ 0.2 times in the dried cream powder obtained, makes particle, in 40 ~ 50 DEG C of dryings, obtains granule.
9. the preparation method of the functional feed for preventing and treating sheep stomatitis according to any one of claim 1-8, it is characterized in that, described preparation method comprises the following steps:
The first step, corn, Chinese sorghum, Ipomoea batatas, potato, mung bean, eggplant, wheat bran, watermelon peel, balsam pear, lotus leaf, air bladder, ginger, wheat and dregs of beans mix by ratio by weight, put in pulverizer and pulverize, and cross 2.0mm sieve after pulverizing;
Second step, takes vitamin premix, microelement pre-mix material and Chinese medicine additive according to ratio of weight and number, pulverizes the fine powder obtained mix with step (1), and drop into mixer, mix, incorporation time is 30-60s;
3rd step, drop into granulator and granulate, pelleting temperature is 85 DEG C, makes its gelatinization degree reach more than 90%.
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| CN201410504273.XA CN104256167A (en) | 2014-09-28 | 2014-09-28 | Functional feed for preventing and treating sheep stomatitis and preparation method thereof |
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| CN106858057A (en) * | 2017-01-23 | 2017-06-20 | 六安市绿丰牧业科技有限公司 | A kind of sheep feed of antibacterial desinsection and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104855736A (en) * | 2015-06-11 | 2015-08-26 | 山东新希望六和集团有限公司 | Pig feed and preparation method thereof |
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| CN106177723A (en) * | 2016-08-02 | 2016-12-07 | 山东新希望六和集团有限公司 | A kind of salmon fish feed additive and preparation method thereof |
| CN106858057A (en) * | 2017-01-23 | 2017-06-20 | 六安市绿丰牧业科技有限公司 | A kind of sheep feed of antibacterial desinsection and preparation method thereof |
| CN106819437A (en) * | 2017-01-24 | 2017-06-13 | 长治市雄丰清真养殖屠宰有限公司 | It is a kind of to prevent ox, the preparation method of the feed of sheep mouth inflammation disease |
| CN107439792A (en) * | 2017-07-01 | 2017-12-08 | 山东阳春羊奶乳业有限公司 | A kind of fermented feed for preventing and treating milch goat stomatitis and preparation method thereof |
| CN109793838A (en) * | 2019-02-22 | 2019-05-24 | 青岛农业大学 | A kind of plaster and preparation method thereof for preventing and treating chiru sheep mouth inflammation |
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Application publication date: 20150107 |