CN104189458A - Traditional Chinese medicine composition for treating fox canine distemper and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating fox canine distemper and preparation method thereof Download PDFInfo
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- CN104189458A CN104189458A CN201410479706.0A CN201410479706A CN104189458A CN 104189458 A CN104189458 A CN 104189458A CN 201410479706 A CN201410479706 A CN 201410479706A CN 104189458 A CN104189458 A CN 104189458A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating fox raccoon dog distemper. The traditional Chinese medicine composition is prepared by ephedra, cassia twig, almonds, liquorice, fagopyrum cymosum, gypsum, ophiopogon, pinellia ternate, ginseng, date, root-bark of tree peony, radix puerariae, fritillaria cirrhosa and asarum. The traditional Chinese medicine composition can be powder. The preparation method of the traditional Chinese medicine composition comprises the following steps: (1) selecting: selecting out all impurities, stones and metal, and removing non-medicinal parts; (2) elutriating: enabling 2-3 times of water to slowly enter medicine by using an infiltration method, so as to ensure that the medicine is infiltrated, and the water is used up; (3) drying: reducing the pressure and drying at a temperature of 40-60 DEG C until complete drying; (4) crushing: slightly crushing various components respectively and screening by using a 600-mesh screen; (5) mixing: weighing according to the weight and uniformly mixing for 10-20 minutes; (6) packaging into bags: ensuring that the weight of each bag is 100-200 g so as to obtain a finished product. The traditional Chinese medicine composition and the preparation method thereof have the benefits that the traditional Chinese medicine composition has the effects of inducing diaphoresis and relieving exterior syndrome, lifting Yang and stopping diarrhoica, clearing lung and eliminating phlegm, eliminating carbuncle and alleviating edema; the composition is a traditional Chinese medicine, is green, has no medicine residue, is safe and reliable and is one of main development directions of medicine for preventing and treating diseases in the fox raccoon aquaculture industry in future.
Description
Technical field
The invention belongs to herbal medicine formulation art, particularly a kind of Chinese medicine composition that is used for the treatment of Vulpes Nyctereutes procyonoides canine distemper and preparation method thereof.
Background technology
Vulpes, Nyctereutes procyonoides canine distemper are acute, hot, the height contagious diseases being caused by canine distemper virus, it shows that disease symptoms is diphasic fever, the mucosal inflammations such as eye, nose, digestive tract, and bronchiolitis, skin eczema and the nervous symptoms deadly infectious disease that is feature, be one of the most serious infectious disease of harm Vulpes Nyctereutes procyonoides, have the title of crushing infectious disease.
Morbidity animal is the most important source of infection of primary disease, and virus is mainly present in nose, discharge of eye and the saliva of inapparent infection and morbidity animal. be also found in lymph node, body fluid, liver, spleen and spinal cord, and can be from the long-term toxin expelling of urine.Pollute surrounding dog and carnivorous economic animal and the concentrated place of animal for display and primary disease easily occurs, young animal susceptible.Morbidity animal initial stage fervescence, spirit is depressed, subtract food. and vomiting sometimes, asoscope are dry.Fall ill and occur canine distemper typical clinical symptom after 2~3 days.Eye conjunctiva starts flushing, swelling.Finally that purulent conjunctivitis, around eyes are come off by hair.In severe one, palpebra inferior is sticked together by purulent secretion.The swelling of asoscope skin be full of cracks nasal inflammation.Flow out purulent secretion, stop up nostril.Dyspnea, when lung is encroached on, cough, cough caused by pathogenic damp after first dry cough, digestive organs generation catarrhal inflammation simultaneously, diarrhoea, be sometimes mixed in the convalescent period of disease or at the beginning adstante febre just there is nervous symptoms spasm, epilepsy, the reactivity stimulating is strengthened.Sometimes go mad and occur at the very start the sick beast of nervous symptoms, be acute process more, the course of disease is short, dead in 3-5 days, is difficult to treatment recovery from illness.
Canine distemper disease is the infectious disease of harm Vulpes Nyctereutes procyonoides aquaculture maximum, and main dependence is at present controlled secondary infection to morbidity colony injection of antibiotics and treated, and curative effect is limited, can not meet clinical demand.Therefore, developing a kind of efficient, green tcm product treatment canine distemper not only can induce sweat and become clinical urgent needs simultaneously but also in can controlling.
Summary of the invention
The problem to be solved in the present invention is: overcome the deficiencies in the prior art, a kind of good effect, no drug residue, safe and reliable Vulpes Nyctereutes procyonoides Chinese medicine composition are provided.
Another technical problem that the present invention will solve is: a kind of Chinese medicine formula that is used for the treatment of Vulpes Nyctereutes procyonoides canine distemper is provided.
Another technical problem that the present invention will solve is: the preparation method of above-mentioned Vulpes Nyctereutes procyonoides with the powder of Chinese medicine composition is provided.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of Chinese medicine composition that is used for the treatment of Vulpes Nyctereutes procyonoides canine distemper, is characterized in that: the raw material by following mass fraction is prepared from: Herba Ephedrae 20-40 part, Ramulus Cinnamomi 20-40 part, Semen Armeniacae Amarum 10-20 part, Radix Glycyrrhizae 20-40 part, Rhizoma Fagopyri Dibotryis 20-40 part, Gypsum Fibrosum 40-60 part, Radix Ophiopogonis 20-40 part, Rhizoma Pinelliae 20-40 part, Radix Ginseng 10-20 part, Fructus Jujubae 20-40 part, Cortex Moutan 10-20 part, Radix Puerariae 10-20 part, Bulbus Fritillariae Cirrhosae 10-20 part, Herba Asari 10-20 part.
Further, the mass fraction of the optimum feed stock of this Chinese medicine composition is as follows:
30 parts, Herba Ephedrae, 30 parts of Ramulus Cinnamomi, 15 parts, Semen Armeniacae Amarum, 30 parts, Radix Glycyrrhizae, 30 parts of Rhizoma Fagopyri Dibotryiss, 50 parts, Gypsum Fibrosum, 30 parts of Radix Ophiopogonis, 30 parts of the Rhizoma Pinelliaes, 15 parts of Radix Ginsengs, 30 parts, Fructus Jujubae, 15 parts of Cortex Moutans, 15 parts of Radix Puerariaes, 15 parts of Bulbus Fritillariae Cirrhosaes, 10 parts of Herba Asaris.
Further, described preparation can be powder.
Further, the preparation method of the powder of said composition is: (1) is selected: choose most impurity, stone and metal, remove non-medicinal part; (2) eluriate: with 2-3 times of water gaging, use soaking method to make water reach medicine in blowing slowly permeable most; (3) dry: 40 ℃ of-60 ℃ of drying under reduced pressure are until dry completely; (4) pulverize: various compositions are crossed to 600 mesh sieves after micronizing respectively; (5) mix: take by weight and mix 10-20min to even; (6) be packaged into bag, every bag of 100-200g, gets product.
Advantage of the present invention and beneficial effect are:
(1) the present invention is according to tcm theory, and science compatibility has retained the combined effect of Chinese medicinal formulae determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, and the Chinese medicine ingredients that the present invention contains can be effective to treat Vulpes Nyctereutes procyonoides canine distemper, and cure rate can reach more than 85%.This prescription has the effect of relieving the exterior syndrome by diaphoresis, yang invigorating antidiarrheal, removing heat from the lung and dissipating phlegm, eliminating carbuncle evacuation of pus.Avoided the residue problem of drug resistance and the medicine of chemicals simultaneously.
(2) characteristic of each raw material of Chinese medicine of the present invention is as follows:
Herba Ephedrae: relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing
Ramulus Cinnamomi: send out that flesh induces sweat, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI
Semen Armeniacae Amarum: depressed lung-energy dispersing
Radix Glycyrrhizae: heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription
Rhizoma Fagopyri Dibotryis: detumescence row carbuncle
Gypsum Fibrosum: clearing away heat-fire
Radix Ophiopogonis: YIN nourishing and the production of body fluid promoting, lung moistening clear away heart-fire
The Rhizoma Pinelliae: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass
Radix Ginseng: strongly invigorating primordial QI
Fructus Jujubae: invigorating the spleen and regulating the stomach, invigorating the spleen and replenishing QI
Cortex Moutan: clearing away heat and cooling blood, promoting blood circulation to remove blood stasis
Radix Puerariae: bring down a fever induce sweat, yang invigorating antidiarrheal
Bulbus Fritillariae Cirrhosae: relieving cough and resolving phlegm
Herba Asari: expelling wind and cold.Row water is had one's ideas straightened out
Side's epheday intermedia, Ramulus Cinnamomi, Radix Puerariae three taste medicine relieving the exterior syndrome by diaphoresis, the expelling pathogenic factors from muscles of bringing down a fever.Be equipped with Herba Asari cold expelling sensible, the symptoms such as the high heat of removing table disease, nasal obstruction.Simultaneously Herba Ephedrae has the effect of depressed lung-energy dispersing, is equipped with that Bulbus Fritillariae Cirrhosae, pinellia tuber for relieving cough reduce phlegm, dissolving lump and resolving mass, can separate expectorant and become silted up and hinder on diaphragm.Radix Ophiopogonis nourishing YIN and moistening the lung, YIN nourishing and the production of body fluid promoting, be used in conjunction with Ke Dui pulmonary and play to control and support synchronous object.Gypsum Fibrosum clearing away heat-fire, can let out the fire that lung-heat is stopped up Sheng.Rhizoma Fagopyri Dibotryis detumescence and apocenosis, Cortex Moutan blood circulation promoting and blood stasis dispelling, can separate the caused eye of canine distemper face etc. and locate swelling.Fructus Jujubae Radix Ginseng strengthening QI of middle-JIAO, protection true strength, short sick morning is more.
The specific embodiment
Below by specific embodiment, the invention will be further described, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
A Chinese powder medicine that is used for the treatment of Vulpes Nyctereutes procyonoides canine distemper, the parts by weight of each raw material are as follows: 30 parts, Herba Ephedrae, 30 parts of Ramulus Cinnamomi, 15 parts, Semen Armeniacae Amarum, 30 parts, Radix Glycyrrhizae, 30 parts of Rhizoma Fagopyri Dibotryiss, 50 parts, Gypsum Fibrosum, 30 parts of Radix Ophiopogonis, 30 parts of the Rhizoma Pinelliaes, 15 parts of Radix Ginsengs, 30 parts, Fructus Jujubae, 15 parts of Cortex Moutans, 15 parts of Radix Puerariaes, 15 parts of Bulbus Fritillariae Cirrhosaes, 10 parts of Herba Asaris.Its preparation method is: (1) is selected: choose most impurity, stone and metal, remove non-medicinal part; (2) eluriate: with 3 times of water gagings use soaking methods, make water reach medicine in blowing slowly permeable most; (3) dry: 60 ℃ of drying under reduced pressure are until dry completely; (4) pulverize: various compositions are crossed to 600 mesh sieves after micronizing respectively; (5) mix: take by weight and mix 20min to even; (6) be packaged into bag, every bag of 200g, gets product.
Embodiment 2
A Chinese powder medicine that is used for the treatment of Vulpes Nyctereutes procyonoides canine distemper, the parts by weight of each raw material are as follows: 25 parts, Herba Ephedrae, 35 parts of Ramulus Cinnamomi, 20 parts, Semen Armeniacae Amarum, 20 parts, Radix Glycyrrhizae, 30 parts of Rhizoma Fagopyri Dibotryiss, 50 parts, Gypsum Fibrosum, 40 parts of Radix Ophiopogonis, 30 parts of the Rhizoma Pinelliaes, 20 parts of Radix Ginsengs, 20 parts, Fructus Jujubae, 15 parts of Cortex Moutans, 15 parts of Radix Puerariaes, 15 parts of Bulbus Fritillariae Cirrhosaes, 10 parts of Herba Asaris.Its preparation method is: (1) is selected: choose most impurity, stone and metal, remove non-medicinal part; (2) eluriate: with 3 times of water gagings use soaking methods, make water reach medicine in blowing slowly permeable most; (3) dry: 60 ℃ of drying under reduced pressure are until dry completely; (4) pulverize: various compositions are crossed to 600 mesh sieves after micronizing respectively; (5) mix: take by weight and mix 20min to even; (6) be packaged into bag, every bag of 200g, gets product.
Embodiment 3
A Chinese powder medicine that is used for the treatment of Vulpes Nyctereutes procyonoides canine distemper, the parts by weight of each raw material are as follows: 40 parts, Herba Ephedrae, 25 parts of Ramulus Cinnamomi, 10 parts, Semen Armeniacae Amarum, 10 parts, Radix Glycyrrhizae, 40 parts of Rhizoma Fagopyri Dibotryiss, 50 parts, Gypsum Fibrosum, 40 parts of Radix Ophiopogonis, 40 parts of the Rhizoma Pinelliaes, 20 parts of Radix Ginsengs, 20 parts, Fructus Jujubae, 15 parts of Cortex Moutans, 15 parts of Radix Puerariaes, 20 parts of Bulbus Fritillariae Cirrhosaes, 20 parts of Herba Asaris.Its preparation method is: (1) is selected: choose most impurity, stone and metal, remove non-medicinal part; (2) eluriate: with 2-3 times of water gaging, use soaking method to make water reach medicine in blowing slowly permeable most; (3) dry: 60 ℃ of drying under reduced pressure are until dry completely; (4) pulverize: various compositions are crossed to 600 mesh sieves after micronizing respectively; (5) mix: take by weight and mix 20min to even; (6) be packaged into bag, every bag of 200g, gets product.
Clinical trial
Experimental example 1:
3000 fox morbidities of Heilungkiang Mou Huhe plant, sick fox lassitude, acute high fever, the mucosa inflammation such as eye, nose, digestive tract, concurrent bronchiolitis.Through clinical diagnosis, be diagnosed as Vulpes Nyctereutes procyonoides canine distemper.2000 foxes are wherein used to the prepared product of embodiment 1.Every 200g spice 100kg, every day twice, treats five days.The 3rd day sick fox symptom of medication alleviates, and body temperature starts to decline, and cough with asthma alleviates.Within the 5th day, jumpbogroup is cured, and cure rate reaches 91%.Another 1000 foxes as a control group, use ofloxacin, with ambroxol salt partner treatment.Cure rate 74%.
Experimental results show that the obtained product of embodiment 1 is evident in efficacy.Can effectively control Vulpes Nyctereutes procyonoides canine distemper.
Experimental example 2:
50000 recoon dogs of Shandong Mou Huhe plant.There is lassitude in 8000 recoon dogs, heating, and eye mucosa inflammation, and with bronchiolitis.Through clinical diagnosis, be diagnosed as Vulpes Nyctereutes procyonoides canine distemper.6000 recoon dogs are wherein used to the prepared product of embodiment 1.Every 200g spice 100kg, every day twice, treats four days.After the 4th day, jumpbogroup is cured, and cure rate is 87%.Another 2000 recoon dogs as a control group, are used cefquinome, dipyrone, ambroxol partner treatment.Within the 5th day, jumpbogroup is cured, cure rate 76%.
Experimental results show that the obtained product of embodiment 1 is evident in efficacy.Can effectively control Vulpes Nyctereutes procyonoides canine distemper.
The above, be only preferred embodiments of the present invention, is illustrative rather than determinate, can list several embodiment according to limited range, therefore in the variation and the modification that do not depart under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (8)
1. a Chinese medicine composition that is used for the treatment of Vulpes Nyctereutes procyonoides canine distemper, is characterized in that: the raw material by following mass fraction is prepared from: Herba Ephedrae 20-40 part, Ramulus Cinnamomi 20-40 part, Semen Armeniacae Amarum 10-20 part, Radix Glycyrrhizae 20-40 part, Rhizoma Fagopyri Dibotryis 20-40 part, Gypsum Fibrosum 40-60 part, Radix Ophiopogonis 20-40 part, Rhizoma Pinelliae 20-40 part, Radix Ginseng 10-20 part, Fructus Jujubae 20-40 part, Cortex Moutan 10-20 part, Radix Puerariae 10-20 part, Bulbus Fritillariae Cirrhosae 10-20 part, Herba Asari 10-20 part.
2. the Chinese medicine composition that is used for the treatment of Vulpes Nyctereutes procyonoides canine distemper according to claim 1, is characterized in that: the mass fraction of optimum feed stock is as follows:
30 parts, Herba Ephedrae, 30 parts of Ramulus Cinnamomi, 15 parts, Semen Armeniacae Amarum, 30 parts, Radix Glycyrrhizae, 30 parts of Rhizoma Fagopyri Dibotryiss, 50 parts, Gypsum Fibrosum, 30 parts of Radix Ophiopogonis, 30 parts of the Rhizoma Pinelliaes, 15 parts of Radix Ginsengs, 30 parts, Fructus Jujubae, 15 parts of Cortex Moutans, 15 parts of Radix Puerariaes, 15 parts of Bulbus Fritillariae Cirrhosaes, 10 parts of Herba Asaris.
3. the Chinese medicine composition that is used for the treatment of Vulpes Nyctereutes procyonoides canine distemper according to claim 1, is characterized in that: described preparation can be powder.
4. prepare a method that is used for the treatment of the Chinese medicine composition of Vulpes Nyctereutes procyonoides canine distemper as claimed in claim 3, it is characterized in that: preparation method is: (1) is selected: choose most impurity, stone and metal, remove non-medicinal part; (2) eluriate: with certain times of water gaging use soaking method, make water reach medicine in blowing slowly permeable most; (3) dry: blood pressure lowering is at a certain temperature dry until dry completely; (4) pulverize: various compositions are sieved after micronizing respectively; (5) mix: take by weight and be mixed to evenly; (6) be packaged into bag, get product.
5. the preparation method that is used for the treatment of the Chinese medicine composition of Vulpes Nyctereutes procyonoides canine distemper according to claim 4, is characterized in that: described elutriation water consumption is 2-3 times.
6. the preparation method that is used for the treatment of the Chinese medicine composition of Vulpes Nyctereutes procyonoides canine distemper according to claim 4, is characterized in that: the dry temperature of blood pressure lowering is 40-60 ℃.
7. the preparation method that is used for the treatment of the Chinese medicine composition of Vulpes Nyctereutes procyonoides canine distemper according to claim 4, is characterized in that: the order number sieving is 600 orders.
8. the preparation method that is used for the treatment of the Chinese medicine composition of Vulpes Nyctereutes procyonoides canine distemper according to claim 4, is characterized in that: the specification of packing is 100-200g/ bag.
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CN104606359A (en) * | 2015-02-13 | 2015-05-13 | 安徽恒源药业有限公司 | Traditional Chinese medicinal preparation for treating porcine respiratory disease |
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Cited By (2)
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