CN104258364A - Traditional Chinese medicine combination for curing hemorrhagic pneumonia of mink and preparation method thereof - Google Patents
Traditional Chinese medicine combination for curing hemorrhagic pneumonia of mink and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine combination for curing hemorrhagic pneumonia of mink. The traditional Chinese medicine combination is prepared by cedar leaf, dried ginger, argyi leaf, Chinese ephedra, almond, gypsum, licorice root, balloonflower, fruit of Chinese magnoliavine and cape jasmine. The traditional Chinese medicine combination can adopt medicinal powder, the preparation method comprises the steps of firstly, selecting: removing impurities, stones and metal, and removing non-medicinal parts, secondly, washing: using water 2 to 3 times of that of the bulk drugs to enable the water slowly enter the bulk drugs through an infiltration method, so as to achieve that the bulk drugs are soaked and no water is left, thirdly, drying: performing drying under reduced pressure on the drugs at 40 to 60 DEG C till the drugs are completely dried; fourthly, grinding: performing superfine grinding on all constituents, then the sieving the drugs through a 80-mesh sieve, fifthly, mixing: weighing the drugs in weight, and uniformly mixing the drugs for 10 to 20min, and sixthly, packaging the drugs into bags, and ensuring that each bag is 100 to 200 g, so as to form finished products. The traditional Chinese medicine combination has the effects of warming the middle-jiao, arresting bleeding or arresting hemorrhage, removing carbuncle, resolving phlegm, clearing away the lung-heat, eliminating pathogenic heat from the blood and relieving cough. The traditional Chinese medicine combination is green, does not has residue, is safe and reliable, and is one of the main development directions of medicine for disease prevention in the mink cultivation industry in the future.
Description
Technical field
The invention belongs to Chinese veterinary drug preparation field, be particularly a kind ofly used for the treatment of Chinese medicine composition of mink hemorrhagic pneumonia and preparation method thereof.
Background technology
Ermine hemorrhagic pneumonia is a kind of acute infectious disease caused by bacillus pyocyaneus, and in recent years, Shandong, northeast, North China large-scale outbreak cross this disease, cause larger economic loss to raiser.Its clinical symptoms for morbidity rapid, sick ermine body temperature raises, and appetite is absolutely useless, dyspnea, ventral breathing, and auscultation lung has sound of vomiting sound, have spit out white foams, blood and slime, before dead, nasal cavity flows out blood and slime, after major part morbidity 1-3 days dead.Dissecting pathological changes main manifestations is pulmonary lesion, pneumorrhagia, hyperemia, consolidation, edema, and what have has kermesinus ecchymosis, and tangent plane oozes out a large amount of blood sample liquid; Hydrothorax; Splenomegaly, there is petechia on surface; , Renal Cortex has petechia or ecchymosis; Bladder, harmonization of the stomach enteric hemorrhage, be mixed with blood in gastric content.Hemorrhagic pneumonia is mainly caused by charrin's disease, and the infection rate of young ermine is higher than the female ermine of suckling, and male ermine is higher than female ermine.
Current mink farming owner will rely on antibiotic therapy mink hemorrhagic pneumonia, but clinical ubiquity is undesirable as effect, the shortcoming that mortality rate is high.Simultaneously antibiotic a large amount of and use lack of standardization also makes drug resistance constantly strengthen.Therefore the Chinese medicine of exploitation treatment mink hemorrhagic pneumonia is not only the demand in market and has broad prospects.
Summary of the invention
The problem to be solved in the present invention is: overcome the deficiencies in the prior art, provides a kind of good effect, no drug residue, safe and reliable mink Chinese medicine composition.
Another technical problem that the present invention will solve is: provide a kind of Chinese medicine formula being used for the treatment of mink hemorrhagic pneumonia.
Another technical problem that the present invention will solve is: the preparation method providing the powder of above-mentioned mink Chinese medicine composition.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of Chinese medicine composition being used for the treatment of mink hemorrhagic pneumonia, is characterized in that: be prepared from by the raw material of following mass fraction: Cacumen Platycladi (Cacumen Biotae) 20-40 part, Rhizoma Zingiberis 20-40 part, Folium Artemisiae Argyi 20-40 part, Herba Ephedrae 20-40 part, Semen Armeniacae Amarum 20-40 part, Gypsum Fibrosum 20-40 part, Radix Glycyrrhizae 20-40 part, Radix Platycodonis 20-40 part, Fructus Schisandrae Chinensis 20-40 part, Fructus Gardeniae 20-40 part.
Further, the mass fraction of the optimum feed stock of this Chinese medicine composition is as follows:
Cacumen Platycladi (Cacumen Biotae) 30 parts, Rhizoma Zingiberis 30 parts, Folium Artemisiae Argyi 30 parts, 30 parts, Herba Ephedrae, 30 parts, Semen Armeniacae Amarum, 40 parts, Gypsum Fibrosum, 40 parts, Radix Glycyrrhizae, Radix Platycodonis 30 parts, Fructus Schisandrae Chinensis 30 parts, Fructus Gardeniae 30 parts.
Further, described preparation can be powder.
Further, the preparation method of the powder of said composition is: (1) is selected: choose most impurity, stone and metal, removes non-medicinal effects; (2) eluriate: with 2-3 times of water gaging use soaking method make water blow slowly in reach medicine permeable most; (3) dry: 40 DEG C of-60 DEG C of drying under reduced pressure are until dry completely; (4) pulverize: cross 80 mesh sieves by after various composition respectively micronizing; (5) mix: take mixing 10-20min by weight to even; (6) be packaged into bag, every bag of 100-200g, gets product.
Advantage of the present invention and beneficial effect are:
(1) the present invention is according to tcm theory, and scientific compatibility, remains the combined effect of Chinese medicinal formulae determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, and the Chinese medicine ingredients that the present invention contains can be effective to treatment mink hemorrhagic pneumonia.This prescription have warming middle-JIAO hemostasis, go carbuncle to reduce phlegm, lung heat clearing heat extraction, removing heat from blood cough-relieving effect.Avoid the drug resistance of chemicals and the residue problem of medicine simultaneously.
(2) characteristic of each raw material of Chinese medicine of the present invention is as follows:
Cacumen Platycladi (Cacumen Biotae): cooling blood for hemostasis, eliminating phlegm and stopping cough.
Rhizoma Zingiberis: cold expelling diaphoresis, preventing phlegm from forming and stopping coughing.
Folium Artemisiae Argyi: enrich blood and invigorate blood circulation.
Herba Ephedrae: relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, inducing diuresis to remove edema.
Semen Armeniacae Amarum: warming the lung and benefiting QI, relieving asthma and cough.
Gypsum Fibrosum: clearing away heat-fire, relieving restlessness quench the thirst, heat-clearing and toxic substances removing.
Radix Glycyrrhizae: heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.
Radix Platycodonis: lung qi dispersing eliminates the phlegm, sore-throat relieving evacuation of pus.
Fructus Schisandrae Chinensis: supplementing QI for promoting the production of body fluid, nourishing kidney of astringing the lung.
Fructus Gardeniae: eliminating fire and detoxication, clearing away heat and cooling blood.
Mink hemorrhagic pneumonia is diseases caused by exogenous pathogenic factor cold-evil according to Chinese medical discrimination, enters interior heat-transformation, so that lung-heat is stopped up and contained, and pathogenic heat enters blood system, the absurd row of forcing blood and cause hemorrhage.Lung-heat stops up Sheng simultaneously, and lung-QI being unable to descend causes the signs such as heating, cough with asthma.The lung and the large intestine being interior-exteriorly related, heat enters the intestines and stomach and causes gastrointestinal hemorrhage, and pathogenic heat harmony of a specified duration must passing stool with blood and pus.Therefore the sick severe one later stage there will be gastrointestinal hemorrhage, discharges the symptoms such as tarry feces.Treatment is when coordinating Semen Armeniacae Amarum, Gypsum Fibrosum, Radix Glycyrrhizae, Radix Platycodonis lung heat clearing heat extraction, relieving cough and resolving phlegm with our Herba Ephedrae.Be aided with effect that Fructus Gardeniae strengthens its clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body.Cacumen Platycladi (Cacumen Biotae), Rhizoma Zingiberis, Folium Artemisiae Argyi three taste medicine can play warming middle-JIAO and stop blooding and the object of preventing phlegm from forming and stopping coughing of holding concurrently.Fructus Schisandrae Chinensis astringing lung-QI and relieving cough, speed is induced sweat disease.
Detailed description of the invention
Below by specific embodiment, the invention will be further described, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
Be used for the treatment of a Chinese powder medicine for mink hemorrhagic pneumonia, the parts by weight of each raw material are as follows: Cacumen Platycladi (Cacumen Biotae) 30 parts, Rhizoma Zingiberis 30 parts, Folium Artemisiae Argyi 30 parts, 30 parts, Herba Ephedrae, 30 parts, Semen Armeniacae Amarum, 40 parts, Gypsum Fibrosum, 40 parts, Radix Glycyrrhizae, Radix Platycodonis 30 parts, Fructus Schisandrae Chinensis 30 parts, Fructus Gardeniae 30 parts.Its preparation method is: (1) is selected: choose most impurity, stone and metal, removes non-medicinal effects; (2) eluriate: with 3 times of water gagings use soaking methods make water blow slowly in reach medicine permeable most; (3) dry: 60 DEG C of drying under reduced pressure are until dry completely; (4) pulverize: cross 80 mesh sieves by after various composition respectively micronizing; (5) mix: take mixing 20min by weight to even; (6) be packaged into bag, every bag of 200g, gets product.
Embodiment 2
Be used for the treatment of a Chinese powder medicine for mink hemorrhagic pneumonia, the parts by weight of each raw material are as follows: Cacumen Platycladi (Cacumen Biotae) 30 parts, Rhizoma Zingiberis 20 parts, Folium Artemisiae Argyi 20 parts, 30 parts, Herba Ephedrae, 30 parts, Semen Armeniacae Amarum, 40 parts, Gypsum Fibrosum, 40 parts, Radix Glycyrrhizae, Radix Platycodonis 40 parts, Fructus Schisandrae Chinensis 30 parts, Fructus Gardeniae 30 parts.Its preparation method is: (1) is selected: choose most impurity, stone and metal, removes non-medicinal effects; (2) eluriate: with 3 times of water gagings use soaking methods make water blow slowly in reach medicine permeable most; (3) dry: 60 DEG C of drying under reduced pressure are until dry completely; (4) pulverize: cross 80 mesh sieves by after various composition respectively micronizing; (5) mix: take mixing 20min by weight to even; (6) be packaged into bag, every bag of 200g, gets product.
Embodiment 3
Be used for the treatment of a Chinese powder medicine for mink hemorrhagic pneumonia, the parts by weight of each raw material are as follows: Cacumen Platycladi (Cacumen Biotae) 35 parts, Rhizoma Zingiberis 30 parts, Folium Artemisiae Argyi 35 parts, 30 parts, Herba Ephedrae, 30 parts, Semen Armeniacae Amarum, 40 parts, Gypsum Fibrosum, 40 parts, Radix Glycyrrhizae, Radix Platycodonis 30 parts, Fructus Schisandrae Chinensis 35 parts, Fructus Gardeniae 30 parts.Its preparation method is: (1) is selected: choose most impurity, stone and metal, removes non-medicinal effects; (2) eluriate: with 2-3 times of water gaging use soaking method make water blow slowly in reach medicine permeable most; (3) dry: 60 DEG C of drying under reduced pressure are until dry completely; (4) pulverize: cross 80 mesh sieves by after various composition respectively micronizing; (5) mix: take mixing 20min by weight to even; (6) be packaged into bag, every bag of 200g, gets product.
Clinical trial
Experimental example 1:
5000, mink farming field, Heilungkiang mink, falls ill 2000, and suffering from edema ermine body temperature raises, and appetite is useless absolutely, dyspnea, ventral breathing, and auscultation lung has sound of vomiting sound, have spit out white foams, blood and slime, before dead, nasal cavity flows out blood and slime, after major part morbidity 1-3 days dead.Dissecting pathological changes main manifestations is pulmonary lesion.Mink hemorrhagic pneumonia is diagnosed as through clinical diagnosis.Product obtained by embodiment 1 is used to the mink of 1000 wherein.Every 200g spice 100kg, every day twice, treats three days.Medication second day suffering from edema ermine symptom alleviates, and temperature decline, cough with asthma is clearly better.Within 3rd day, jumpbogroup is cured, and cure rate reaches 96.5%.Another 1000 minks as a control group, use ofloxacin and gentamycin partner treatment.Cure rate 74%.
Experiment proves that obtained by embodiment 1, product is evident in efficacy.Can effectively control mink hemorrhagic pneumonia.
The above, be only preferred embodiments of the present invention, is illustrative instead of determinate, can list several embodiments according to limited range, therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (8)
1. be used for the treatment of a Chinese medicine composition for mink hemorrhagic pneumonia, it is characterized in that: be prepared from by the raw material of following mass fraction: Cacumen Platycladi (Cacumen Biotae) 20-40 part, Rhizoma Zingiberis 20-40 part, Folium Artemisiae Argyi 20-40 part, Herba Ephedrae 20-40 part, Semen Armeniacae Amarum 20-40 part, Gypsum Fibrosum 20-40 part, Radix Glycyrrhizae 20-40 part, Radix Platycodonis 20-40 part, Fructus Schisandrae Chinensis 20-40 part, Fructus Gardeniae 20-40 part.
2. the Chinese medicine composition being used for the treatment of mink hemorrhagic pneumonia according to claim 1, is characterized in that: the mass fraction of optimum feed stock is as follows:
Cacumen Platycladi (Cacumen Biotae) 30 parts, Rhizoma Zingiberis 30 parts, Folium Artemisiae Argyi 30 parts, 30 parts, Herba Ephedrae, 30 parts, Semen Armeniacae Amarum, 40 parts, Gypsum Fibrosum, 40 parts, Radix Glycyrrhizae, Radix Platycodonis 30 parts, Fructus Schisandrae Chinensis 30 parts, Fructus Gardeniae 30 parts.
3. the Chinese medicine composition being used for the treatment of mink hemorrhagic pneumonia according to claim 1, is characterized in that: described preparation can be powder.
4. prepare a method for the Chinese medicine composition being used for the treatment of mink hemorrhagic pneumonia as claimed in claim 3, it is characterized in that: preparation method is: (1) is selected: choose most impurity, stone and metal, remove non-medicinal effects; (2) eluriate: with certain times of water gaging use soaking method make water blow slowly in reach medicine permeable most; (3) dry: blood pressure lowering is at a certain temperature dry until dry completely; (4) pulverize: sieve after various composition respectively micronizing; (5) mix: take by weight and be mixed to evenly; (6) be packaged into bag, get product.
5. the preparation method being used for the treatment of the Chinese medicine composition of mink hemorrhagic pneumonia according to claim 4, is characterized in that: described elutriation water consumption is 2-3 times.
6. the preparation method being used for the treatment of the Chinese medicine composition of mink hemorrhagic pneumonia according to claim 4, is characterized in that: the temperature of blood pressure lowering drying is 40-60 DEG C.
7. the preparation method being used for the treatment of the Chinese medicine composition of mink hemorrhagic pneumonia according to claim 4, is characterized in that: the order number sieved is 80 orders.
8. the preparation method being used for the treatment of the Chinese medicine composition of mink hemorrhagic pneumonia according to claim 4, is characterized in that: the specification of packaging is 100-200g/ bag.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105079739A (en) * | 2015-07-27 | 2015-11-25 | 翟海生 | Medicine for preventing and treating mink anthracnose |
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Non-Patent Citations (2)
| Title |
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| 张传美等: "16种中药对水貂绿脓杆菌的体外抑菌试验", 《动物医学进展》 * |
| 葛铭等编著: "《毛皮动物生态养殖技术》", 31 July 2011 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105079739A (en) * | 2015-07-27 | 2015-11-25 | 翟海生 | Medicine for preventing and treating mink anthracnose |
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Application publication date: 20150107 |