CN104159607A - 用于治疗致癌病毒多肽阳性肿瘤的多核苷酸 - Google Patents

用于治疗致癌病毒多肽阳性肿瘤的多核苷酸 Download PDF

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Publication number
CN104159607A
CN104159607A CN201380012419.2A CN201380012419A CN104159607A CN 104159607 A CN104159607 A CN 104159607A CN 201380012419 A CN201380012419 A CN 201380012419A CN 104159607 A CN104159607 A CN 104159607A
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deletion
point mutation
oncogenic
polypeptide
nucleotide sequence
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J.H.李
D.W.弗米尔
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Sanford Health
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Sanford Research USD
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A61K2039/525—Virus
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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    • C12N2710/10011—Adenoviridae
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    • C12N2710/20011—Papillomaviridae
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    • C12N2710/20071—Demonstrated in vivo effect

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  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
CN201380012419.2A 2012-01-24 2013-01-23 用于治疗致癌病毒多肽阳性肿瘤的多核苷酸 Pending CN104159607A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910216555.2A CN110042110A (zh) 2012-01-24 2013-01-23 用于治疗致癌病毒多肽阳性肿瘤的多核苷酸

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261590089P 2012-01-24 2012-01-24
US61/590,089 2012-01-24
PCT/US2013/022696 WO2013112549A1 (en) 2012-01-24 2013-01-23 Polynucleotides for treating oncogenic viral polypeptide positive tumors

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CN201910216555.2A Pending CN110042110A (zh) 2012-01-24 2013-01-23 用于治疗致癌病毒多肽阳性肿瘤的多核苷酸

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US (3) US9492526B2 (enExample)
EP (2) EP3269387B1 (enExample)
JP (2) JP6219849B2 (enExample)
KR (1) KR102195196B1 (enExample)
CN (2) CN104159607A (enExample)
DK (1) DK2806889T3 (enExample)
ES (1) ES2646590T3 (enExample)
HK (1) HK1203833A1 (enExample)
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Cited By (1)

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CN109891405A (zh) * 2016-11-11 2019-06-14 谷歌有限责任公司 基于用户装置的消费模式来修改视频内容在用户装置上的呈现的方法、系统和介质

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EP3218504B1 (en) 2014-11-13 2020-07-22 Université de Genève Tri-segmented arenaviruses as vaccine vectors
HK1246183A1 (zh) 2015-06-10 2018-09-07 Hookipa Biotech Gmbh Hpv疫苗
SI3371316T1 (sl) 2015-11-04 2023-02-28 Hookipa Biotech Gmbh Cepivo proti virusu hepatitisa B
WO2017080920A1 (en) 2015-11-12 2017-05-18 Hookipa Biotech Ag Arenavirus particles as cancer vaccines
AU2017205270B2 (en) 2016-01-08 2024-01-18 Nykode Therapeutics ASA Therapeutic anticancer neoepitope vaccine
GB201605210D0 (en) * 2016-03-29 2016-05-11 Oxford Immunotec Ltd Assay
EP3463577A4 (en) * 2016-06-03 2019-12-04 Etubics Corporation COMPOSITIONS AND METHODS FOR TREATING DISEASES ASSOCIATED WITH HUMAN PAPILLOMVIRUS (HPV)
CN106655327A (zh) * 2016-10-18 2017-05-10 云南中烟工业有限责任公司 一种压缩式充电装置
JP7581048B2 (ja) 2018-03-06 2024-11-12 プレシゲン，インコーポレイテッド ヒトパピローマウイルスワクチンおよびその使用
KR102712588B1 (ko) * 2020-05-25 2024-10-02 (주)진매트릭스 사람 파필로마바이러스의 구조적으로 변형된 키메라 폴리펩타이드 및 그 폴리펩타이드를 포함하는 재조합 단백질 및 그 단백질의 용도
CA3178325A1 (en) * 2020-05-25 2021-12-02 Soo Ok Kim Structurally modified chimeric polypeptide of human papillomavirus, recombinant protein comprising same polypeptide, and use of same protein

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WO1999061608A2 (en) * 1998-05-26 1999-12-02 Institute Of Molecular And Cell Biology Polypeptides from creb binding protein and related protein p300 for use in transcriptional regulation
CN101688223A (zh) * 2007-05-15 2010-03-31 特兰斯吉恩股份有限公司 用于多基因表达的载体

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ANNA-MARIJA HELT ET AL.: "Inactivation of both the Retinoblastoma Tumor Suppressor and p21 by the Human Papillomavirus Type 16 E7 Oncoprotein Is Necessary To Inhibit Cell Cycle Arrest in Human Epithelial Cells", 《JOURNAL OF VIROLOGY》 *
BRYANT G. WIEKING ET AL.: "A Non-oncogenic HPV 16 E6/E7 Vaccine Enhances Treatment of HPV Expressing Tumors", 《CANCER GENE THERAPY》 *
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109891405A (zh) * 2016-11-11 2019-06-14 谷歌有限责任公司 基于用户装置的消费模式来修改视频内容在用户装置上的呈现的方法、系统和介质
US11758228B2 (en) 2016-11-11 2023-09-12 Google Llc Methods, systems, and media for modifying the presentation of video content on a user device based on a consumption of the user device
CN109891405B (zh) * 2016-11-11 2023-09-26 谷歌有限责任公司 基于用户装置的消费模式来修改视频内容在用户装置上的呈现的方法、系统和介质
US12170819B2 (en) 2016-11-11 2024-12-17 Google Llc Methods, systems, and media for modifying the presentation of video content on a user device based on a consumption of the user device

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JP2015506179A (ja) 2015-03-02
HK1203833A1 (en) 2015-11-06
US20150023996A1 (en) 2015-01-22
US20160376324A1 (en) 2016-12-29
US9492526B2 (en) 2016-11-15
JP2018038405A (ja) 2018-03-15
IN2014DN06118A (enExample) 2015-08-14
EP3269387B1 (en) 2019-07-17
KR20140131929A (ko) 2014-11-14
US9969779B2 (en) 2018-05-15
CN110042110A (zh) 2019-07-23
JP6655051B2 (ja) 2020-02-26
EP2806889A4 (en) 2016-04-20
WO2013112549A1 (en) 2013-08-01
KR102195196B1 (ko) 2020-12-28
DK2806889T3 (da) 2017-11-20
JP6219849B2 (ja) 2017-10-25
EP2806889B1 (en) 2017-08-16
EP2806889A1 (en) 2014-12-03
ES2646590T3 (es) 2017-12-14
US20180237477A1 (en) 2018-08-23
EP3269387A1 (en) 2018-01-17

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