CN104147237A - Anti-fatigue sea horse buccal tablet and preparation method thereof - Google Patents
Anti-fatigue sea horse buccal tablet and preparation method thereof Download PDFInfo
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- CN104147237A CN104147237A CN201310178485.9A CN201310178485A CN104147237A CN 104147237 A CN104147237 A CN 104147237A CN 201310178485 A CN201310178485 A CN 201310178485A CN 104147237 A CN104147237 A CN 104147237A
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- hippocampus
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Abstract
The invention relates to an anti-fatigue sea horse buccal tablet and a preparation method thereof. The anti-fatigue sea horse buccal tablet disclosed by the invention is composed of the following components in parts by weight: 12-25 parts of sea horse, 5-15 parts of medlar, 5-15 parts of lucid ganoderma, 5-15 parts of rhodiola rosea, 10-20 parts of a filler, 1-5 parts of a lubricant, 1-5 parts of an adhesive and 1-5 parts of a condiment. The anti-fatigue sea horse buccal tablet disclosed by the invention has the better effect of relieving fatigue and high safety and can be taken for a long time.
Description
Technical field
The present invention relates to a kind of buccal tablet, more particularly, relate to a kind of resisting fatigue buccal tablet and preparation method thereof.
Background technology
Hippocampus is Syngnathidae animal, and warm in nature, sweet in the mouth is the famous and precious strong traditional tonic medicine material of China.Edition Hippocampus medical material of pharmacopeia collection is gone through by China 5 kinds: the dry body of strain line Hippocampus, HIPPOCAMPUS, large Hippocampus, hippocampus trimaculatus Leacs and little Hippocampus, has warming the kidney to invigorate YANG, effect of mass dissipating and swelling eliminating.Hippocampus has higher nutritive value, and protein content, up to 70%, contains 7 seed amino acids, and seven kinds 7 kinds is essential amino acid; Also containing a large amount of DHA, is the main matter basis of prostate and sperm; It is relevant with benefiting action that Hippocampus contains abundant phospholipid, and in Hippocampus, Mn, Zn content height coincide with kidney invigorating and YANG supporting effect, and are rich in Fe, relevant to its nourishing the liver and kidney blood enriching and generation of vital essence promoting effect.Modern pharmacology studies have shown that, Hippocampus has very many-sided pharmacological action.
Along with scientific and technical progress and expanding economy, people's rhythm of life is accelerated day by day, pressure from each side such as work, life and societies increased severely with day, cause majority very easily tired, immunologic hypofunction, people, in order to improve and alleviate fatigue symptom, have developed various fatigue-resistant drug compositions.But these fatigue-resistant drug compositions can not play the effect of fatigue alleviating fully, and safety issue while there is long-term taking.
Summary of the invention
The object of the present invention is to provide a kind of resisting fatigue Hippocampus buccal tablet.
For realizing object of the present invention, technical scheme of the present invention is as follows:
A kind of resisting fatigue Hippocampus buccal tablet, this buccal tablet is made up of the component of following weight portion:
Hippocampus 12-25 part,
Fructus Lycii 5-15 part,
Ganoderma 5-15 part,
Radix Rhodiolae 5-15 part,
Filler 10-20 part,
Lubricant 1-5 part,
Adhesive 1-5 part,
Flavoring agent 1-5 part.
Wherein, the dosage of every buccal tablet is 0.5g.
In a preferred embodiment of the present invention, described filler is one or more the mixture in Icing Sugar, mannitol, maltose, lactose, sucrose or starch.
In a preferred embodiment of the present invention, described lubricant is magnesium stearate.
In a preferred embodiment of the present invention, described adhesive is 2-6% 30 POVIDONE K 30 BP/USP
3050% alcoholic solution, Gonak.
In a preferred embodiment of the present invention, described adhesive is 5% 30 POVIDONE K 30 BP/USP
3050% alcoholic solution.
In a preferred embodiment of the present invention, described flavoring agent is Mentholum.
Hippocampus has the medicinal functions such as building body, kidney invigorating and YANG supporting, relaxing muscles and tendons and activating QI and blood in the collateral, anti-inflammatory analgetic, tranquillizing and allaying excitement, relieving cough and asthma; A large number of nutrients that Fructus Lycii is contained, all has liver and kidney tonifying, tonifying the spleen and stomach, the Fructus Alpiniae Oxyphyllae of calming the nerves, bone and muscle strengthening, adds the function of vital essence; Ganoderma contains polysaccharide, three note class materials, and both all have good enhancing human body immunity and anti-fatigue effect.
Another object of the present invention is to provide a kind of preparation method of resisting fatigue Hippocampus buccal tablet.
A preparation method for resisting fatigue Hippocampus buccal tablet, the method comprises the following steps:
(1) Hippocampus of formula ratio, Fructus Lycii, Ganoderma, Radix Rhodiolae, filler are decocted with water 2 times, 1 hour for the first time, 2 hours for the second time, filter, filtrate is concentrated, and concentrated solution adds ethanol to make alcohol content reach 70%, cold preservation (1～3 DEG C) 20 hours, filter, filtrate recycling ethanol is also concentrated into thick paste, dry, pulverize, sieve, make mixed powder fineness reach 120-200 order, use 5% 30 POVIDONE K 30 BP/USP
3050% alcoholic solution is to this fine powder granule processed;
(2) lubricant of the flavoring agent of formula ratio and tabletting being used mixes with the granule being obtained by step (1), and after mix homogeneously, tabletting gets product.
The instructions of taking of Hippocampus buccal tablet: three times on the one, each three one month is a course for the treatment of.If desired, can use continuously.
Effect of the present invention is: the total effective rate of allaying tiredness is 92.5%, has no side effect.
Detailed description of the invention
Further illustrate the present invention below by specific embodiment
Embodiment 1
(1) formula of resisting fatigue Hippocampus buccal tablet (100)
Hippocampus 15g,
Fructus Lycii 5g,
Ganoderma 5g,
Radix Rhodiolae 10g,
Icing Sugar 8.5g,
Magnesium stearate 1.5g,
5% 30 POVIDONE K 30 BP/USP
3050% alcoholic solution 3.5g,
Mentholum 1.5g.
(2) preparation method of resisting fatigue Hippocampus buccal tablet
(1) Hippocampus of formula ratio, Fructus Lycii, Ganoderma, Radix Rhodiolae, Icing Sugar are decocted with water 2 times, 1 hour for the first time, 2 hours for the second time, filter, filtrate is concentrated, and concentrated solution adds ethanol to make alcohol content reach 70%, cold preservation (1～3 DEG C) 20 hours, filter, filtrate recycling ethanol is also concentrated into thick paste, dry, pulverize, sieve, make mixed powder fineness reach 120-200 order, use 5% 30 POVIDONE K 30 BP/USP
3050% alcoholic solution is to this fine powder granule processed;
(2) magnesium stearate of the Mentholum of formula ratio and tabletting being used is mixed with the granule being obtained by step (1), and after mix homogeneously, tabletting gets product.
Embodiment 2
(1) formula of resisting fatigue Hippocampus buccal tablet (100)
Hippocampus 13g,
Fructus Lycii 5g,
Ganoderma 7g,
Radix Rhodiolae 8g,
Maltose 10.5g,
Magnesium stearate 2.0g,
5% 30 POVIDONE K 30 BP/USP
3050% alcoholic solution 2.5g,
Mentholum 2.0g.
(2) preparation method of resisting fatigue Hippocampus buccal tablet
(1) Hippocampus of formula ratio, Fructus Lycii, Ganoderma, Radix Rhodiolae, maltose are decocted with water 2 times, 1 hour for the first time, 2 hours for the second time, filter, filtrate is concentrated, and concentrated solution adds ethanol to make alcohol content reach 70%, cold preservation (1～3 DEG C) 20 hours, filter, filtrate recycling ethanol is also concentrated into thick paste, dry, pulverize, sieve, make mixed powder fineness reach 120-200 order, use 5% 30 POVIDONE K 30 BP/USP
3050% alcoholic solution is to this fine powder granule processed;
(2) magnesium stearate of the Mentholum of formula ratio and tabletting being used is mixed with the granule being obtained by step (1), and after mix homogeneously, tabletting gets product.
Embodiment 3
(1) formula of resisting fatigue Hippocampus buccal tablet (100)
Hippocampus 20g,
Fructus Lycii 5g,
Ganoderma 6g,
Radix Rhodiolae 5g,
Lactose 7.5g,
Magnesium stearate 1.5g,
5% 30 POVIDONE K 30 BP/USP
3050% alcoholic solution 3.5g,
Mentholum 1.5g.
(2) preparation method of resisting fatigue Hippocampus buccal tablet
(1) Hippocampus of formula ratio, Fructus Lycii, Ganoderma, Radix Rhodiolae, lactose are decocted with water 2 times, 1 hour for the first time, 2 hours for the second time, filter, filtrate is concentrated, and concentrated solution adds ethanol to make alcohol content reach 70%, cold preservation (1～3 DEG C) 20 hours, filter, filtrate recycling ethanol is also concentrated into thick paste, dry, pulverize, sieve, make mixed powder fineness reach 120-200 order, use 5% 30 POVIDONE K 30 BP/USP
3050% alcoholic solution is to this fine powder granule processed;
(2) magnesium stearate of the Mentholum of formula ratio and tabletting being used is mixed with the granule being obtained by step (1), and after mix homogeneously, tabletting gets product.
Claims (7)
1. a resisting fatigue Hippocampus buccal tablet, is characterized in that, this buccal tablet is made up of the component of following weight portion:
Hippocampus 12-25 part,
Fructus Lycii 5-15 part,
Ganoderma 5-15 part,
Radix Rhodiolae 5-15 part,
Filler 10-20 part,
Lubricant 1-5 part,
Adhesive 1-5 part,
Flavoring agent 1-5 part.
Wherein, the dosage of every buccal tablet is 0.5g.
2. resisting fatigue Hippocampus buccal tablet according to claim 1, is characterized in that, described filler is one or more the mixture in Icing Sugar, mannitol, maltose, lactose, sucrose or starch.
3. resisting fatigue Hippocampus buccal tablet according to claim 1, is characterized in that, described lubricant is magnesium stearate.
4. resisting fatigue Hippocampus buccal tablet according to claim 1, is characterized in that, described adhesive is 2-6% 30 POVIDONE K 30 BP/USP
3050% alcoholic solution, Gonak.
5. resisting fatigue Hippocampus buccal tablet according to claim 4, is characterized in that, described adhesive is 5% 30 POVIDONE K 30 BP/USP
3050% alcoholic solution.
6. resisting fatigue Hippocampus buccal tablet according to claim 1, is characterized in that, described flavoring agent is Mentholum.
7. according to the preparation method of the resisting fatigue Hippocampus buccal tablet described in claim 1-6 any one, it is characterized in that, the method comprises the following steps:
(1) Hippocampus of formula ratio, Fructus Lycii, Ganoderma, Radix Rhodiolae, filler are decocted with water 2 times, 1 hour for the first time, 2 hours for the second time, filter, filtrate is concentrated, and concentrated solution adds ethanol to make alcohol content reach 70%, cold preservation (1～3 DEG C) 20 hours, filter, filtrate recycling ethanol is also concentrated into thick paste, dry, pulverize, sieve, make mixed powder fineness reach 120-200 order, use 5% 30 POVIDONE K 30 BP/USP
3050% alcoholic solution is to this fine powder granule processed;
(2) lubricant of the flavoring agent of formula ratio and tabletting being used mixes with the granule being obtained by step (1), and after mix homogeneously, tabletting gets product.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310178485.9A CN104147237A (en) | 2013-05-15 | 2013-05-15 | Anti-fatigue sea horse buccal tablet and preparation method thereof |
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| CN201310178485.9A CN104147237A (en) | 2013-05-15 | 2013-05-15 | Anti-fatigue sea horse buccal tablet and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110521965A (en) * | 2019-09-17 | 2019-12-03 | 海南医学院 | A kind of hippocampus glue and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1824026A (en) * | 2005-02-24 | 2006-08-30 | 香港生物科技研究院有限公司 | Chinese medicine for improving memory and its preparation method |
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- 2013-05-15 CN CN201310178485.9A patent/CN104147237A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1824026A (en) * | 2005-02-24 | 2006-08-30 | 香港生物科技研究院有限公司 | Chinese medicine for improving memory and its preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 曹国英: "《疗养技术常规》", 30 September 1999, 人民军医出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110521965A (en) * | 2019-09-17 | 2019-12-03 | 海南医学院 | A kind of hippocampus glue and preparation method thereof |
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Application publication date: 20141119 |
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