CN103495019B - A kind of tranquilizing by nourishing the heart Chinese medicine preparation and preparation method thereof - Google Patents

A kind of tranquilizing by nourishing the heart Chinese medicine preparation and preparation method thereof Download PDF

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Publication number
CN103495019B
CN103495019B CN201310466044.9A CN201310466044A CN103495019B CN 103495019 B CN103495019 B CN 103495019B CN 201310466044 A CN201310466044 A CN 201310466044A CN 103495019 B CN103495019 B CN 103495019B
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radix
tranquilizing
nourishing
preparation
chinese medicine
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CN201310466044.9A
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CN103495019A (en
Inventor
孙晓莉
郑雪冰
窦逾常
马丕勇
郑大为
李红艳
宗敏茹
辛光大
霍鹏飞
杨海玲
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Jilin University
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Jilin University
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Abstract

The invention discloses a kind of tranquilizing by nourishing the heart Chinese medicine preparation and preparation method thereof, make preparation with pure Chinese herbal medicine, there is effect of reinforcing the heart kidney, the liver benefiting, strengthening the spleen and stomach, by regulating viscera QI and blood function, benefiting QI and nourishing blood, tranquilizing the mind, plays the health-care effect of improving water flood jointly from too many levels.Toxic and side effects is little, treating both the principal and secondary aspects of a disease, evident in efficacy, and clinical symptom disappearance is rapid, without rebound phenomena after curing.

Description

A kind of tranquilizing by nourishing the heart Chinese medicine preparation and preparation method thereof
technical field:
The invention discloses a kind of tranquilizing by nourishing the heart Chinese medicine preparation and preparation method thereof, there is tranquilizing by nourishing the heart, the relieving restlessness that clears away heart-fire, dispersing the stagnated live-QI to relieve the stagnation of QI, nourishing the liver and kidney effect, belong to Chinese medicine pharmaceutical technology sectors.
background technology:
Have a sleepless night not enough with the length of one's sleep, not and can not allaying tiredness, regain one's strength with energy be principal character to Depth of sleep.Along with the harmful effect of the factor such as increase and medicine of modern's stress, the troop of insomniac quietly grows.According to incompletely statistics, the whole world about has the people of 25% to suffer from insomnia in various degree.
At present, domestic and international doctor trained in Western medicine mainly adopts anxiolytic drugs to stabilize class treatment, some symptom of patient can be improved, but side effect is comparatively large, occurs that look suppresses, flagging phenomenon, life-time service causes patient to the dependency of medicine, medication can be fallen asleep, and not medication can not be fallen asleep, and dosage also strengthens unsatisfactory curative effect gradually.The traditional Chinese medical science thinks that neurasthenia, restlessness of asrhenia type and insomnia are by deficiency of liver-blood, blood failing to tonify the heart, and caused by yin asthenia generating intrinsic heat, Chinese medicine has very large potentiality in this disease for the treatment of.
On domestic market, Chinese medicine preparation variety is few, though existing Chinese medicine preparation kind has certain curative effect, drug effect plays comparatively slow, is difficult to the requirement meeting patient.
Summary of the invention
The object of the invention is to open a kind of tranquilizing by nourishing the heart Chinese medicine preparation and preparation method thereof, evident in efficacy, shorten treatment cycle, reduce medical expense, improve therapeutic effect, simplify Therapeutic Method.
According to motherland's theory of Chinese medical science, insomnia mainly due to the imbalance of YIN and YANG of the heart, gallbladder, spleen, kidney, qi-blood disharmony so that lack of preservation of spirit or irritability.The present invention selects the pure natural Chinese herbal medicine of the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind, spleen invigorating resolving depression, liver and kidney tonifying, the function of adjustment viscera QI and blood, thus reaches tranquilizing the mind, the object of improving water flood.
a kind of tranquilizing by nourishing the heart Chinese medicine preparation disclosed by the invention, by following raw materials by weight portion than making:
Rhizoma Coptidis 15 ~ 20, Colla Corii Asini 15 ~ 20, Radix Bupleuri 15 ~ 20, Fructus Aurantii 15 ~ 20, Pericarpium Citri Reticulatae Viride 15 ~ 20, the Radix Rehmanniae 15 ~ 20, Poria 15 ~ 20, Radix Ophiopogonis 15 ~ 20, Concha Margaritifera 50 ~ 60, Radix Polygalae 15 ~ 20, Semen Ziziphi Spinosae (parched) 50 ~ 60, Dens Draconis 3 ~ 5, succinum 7 ~ 10, Radix Salviae Miltiorrhizae 15 ~ 20, Caulis Polygoni Multiflori 15 ~ 20.
The optimum ratio of medicine of the present invention is:
Rhizoma Coptidis 20, Colla Corii Asini 20, Radix Bupleuri 20, Fructus Aurantii 20, Pericarpium Citri Reticulatae Viride 20, the Radix Rehmanniae 20, Poria 20, Radix Ophiopogonis 20, Concha Margaritifera 60, Radix Polygalae 20, Semen Ziziphi Spinosae (parched) 60, Dens Draconis 5, succinum 10, Radix Salviae Miltiorrhizae 20, Caulis Polygoni Multiflori 20.
the preparation method of tranquilizing by nourishing the heart Chinese medicine preparation disclosed by the invention, comprises the following steps:
Take above-mentioned raw materials by weight as follows, after removing foreign material, be ground into 100 ~ 200 order fine powders, obtain final product.
usage and dosage:oral, 3 times/day; 5 ~ 8 grams/times 15 days is a course for the treatment of.
function:tranquilizing by nourishing the heart, soothing liver-QI for relieving depression, nourishing the liver and kidney.
cure mainly:insomnia and dreamful sleep, vexed cardiopalmus, weak, xerostomia ear toot, sighing frequently, forgetful, Yao Xi Acid is soft, frequent micturition etc.
The present invention, according to the combination principle of " monarch, minister, help, make ", makes to be required to be use mutually between each medicine, jointly plays therapeutical effect.The effect of succinum, Rhizoma Coptidis, Colla Corii Asini restoring normal coordination between the heart and kidney, tranquillizing and allaying excitement, for restlessness of asrhenia type and insomnia, palpitation with fear dreaminess; The effect of Radix Bupleuri, Fructus Aurantii, Pericarpium Citri Reticulatae Viride, Poria dispersing the stagnated live-QI to relieve the stagnation of QI, spleen-benefiting mind-tranquilizing; The Radix Rehmanniae, enriching yin and nourishing kidney Radix Ophiopogonis; Concha Margaritifera, Dens Draconis are with the use of working arresting convulsion of calming the nerves; The all medicines of Radix Salviae Miltiorrhizae, Caulis Polygoni Multiflori, Radix Polygalae, Semen Ziziphi Spinosae (parched) are with the use of jointly playing the blood and without stagnant the covering of stream of nourishing heart, the merit of tranquilizing mind and tool resolving depression.Reach tranquilizing by nourishing the heart calmness, the effect of the relieving restlessness resolving depression that clears away heart-fire, thus improving water flood quality.
For showing the therapeutic effect of medicine of the present invention, selected 100 routine sleep disorder persons, take medicine of the present invention and treat, carry out statistical analysis be summarized as follows through system clinical observation:
One, clinical manifestation
Insomnia and dreamful sleep, vexed cardiopalmus, weak, xerostomia ear toot, sighing frequently, forgetful palpitation with fear, Yao Xi Acid soft, frequent micturition, staring spells, sleep disorder.
Two, curative effect determinate standard
Clinical cure: various symptom all disappears.
Effective: various symptom is obviously improved.
Effective: various symptom makes moderate progress.
Invalid: various symptom is without change.
Three, therapeutic outcome
100 routine sleep disorder patients, clinical cure 65 example (65%); Effective 28 examples (28%); Effective 7 examples (7%); Invalid 0 example.Total effective rate is 100%.
good effect of the present invention is:
Select pure Chinese herbal medicine to make preparation, have effect of reinforcing the heart kidney, the liver benefiting, strengthening the spleen and stomach, by regulating viscera QI and blood function, benefiting QI and nourishing blood, tranquilizing the mind, plays the health-care effect of improving water flood jointly from too many levels.Toxic and side effects is little, treating both the principal and secondary aspects of a disease, evident in efficacy, and clinical symptom disappearance is rapid, without rebound phenomena after curing.
detailed description of the invention:
To be illustrated further description the present invention by following examples, and do not limit the present invention in any way, under the prerequisite not deviating from technical solution of the present invention, any change that those of ordinary skill in the art made for the present invention easily realize or change all will fall within right of the present invention.
embodiment 1
Take Rhizoma Coptidis 15g, Colla Corii Asini 15g, Radix Bupleuri 15g, Fructus Aurantii 15g, Pericarpium Citri Reticulatae Viride 15g, Radix Rehmanniae 15g. Poria 15g, Radix Ophiopogonis 15g, Concha Margaritifera 50g, Radix Polygalae 15g, Semen Ziziphi Spinosae (parched) 50g, Dens Draconis 3g, succinum 7g, Radix Salviae Miltiorrhizae 15g, Caulis Polygoni Multiflori 15g remove after foreign material, other are ground into 100 order fine powders, under should meet People's Republic of China's version pharmacopeia fine powder item in 2000.
embodiment 2
Get Rhizoma Coptidis 20g, Colla Corii Asini 20g, Radix Bupleuri 20g, Fructus Aurantii 20g, Pericarpium Citri Reticulatae Viride 20g, Radix Rehmanniae 20g, Poria 20g, Radix Ophiopogonis 20g, Concha Margaritifera 60g, Radix Polygalae 20g, Semen Ziziphi Spinosae (parched) 60g, Dens Draconis 5g, succinum 10g, Radix Salviae Miltiorrhizae 20g, Caulis Polygoni Multiflori 20g remove after foreign material, other are ground into 150 order fine powders, under should meet People's Republic of China's version pharmacopeia fine powder item in 2000.
embodiment 3
Get Rhizoma Coptidis 18g, Colla Corii Asini 18g, Radix Bupleuri 18g, Fructus Aurantii 18g, Pericarpium Citri Reticulatae Viride 18g, Radix Rehmanniae 18g, Poria 18g, Radix Ophiopogonis 18g, Concha Margaritifera 55g, Radix Polygalae 18g, Semen Ziziphi Spinosae (parched) 55g, Dens Draconis 4g, succinum 8g, Radix Salviae Miltiorrhizae 18g, Caulis Polygoni Multiflori 18g remove after foreign material, other are ground into 100 ~ 200 order fine powders, under should meet People's Republic of China's version pharmacopeia fine powder item in 2000.
selected following case further illustrates curative effect of the present invention:
case 1
Zhu, man, 18 years old, student, went to a doctor with " sleep disorder ".Medical syndrome: dysphoria and insomnia, parched lips is flushing, thirst and desire for cold drink, and extremity are twitched slightly, and yellow urine is few, and red tongue, tongue are few, deep,thready and rapid pulse.By Drug therapy of the present invention, oral 3 times/day, 6 grams/times, within 15 days, be 1 course for the treatment of, totally 2 courses for the treatment of, disease is all recovered.Follow up a case by regular visits to 12 months, the state of an illness does not recur.
case 2
Lee, man, 37 years old, civil servant, went to a doctor with " sleep disorder ".Medical syndrome: night does not fall asleep, palpitation with irritability, dry mouth and throat, feverish sensation in the palms and soles, red tongue, few tongue, thready pulse and counting.By Drug therapy of the present invention, oral 3 times/day, 8 grams/times, within 15 days, be 1 course for the treatment of, totally 3 courses for the treatment of, disease is all recovered.Follow up a case by regular visits to 12 months, the state of an illness does not recur.
case 3
Bai, female, 46 years old, line manager, went to a doctor with " sleep disorder ".Medical syndrome: previously suffer from neurosis 8 years, imitates less all over the agent taking calmness of calming the nerves, before first quarter moon, lies awake all night, have difficulty in going to sleep, dizziness and tinnitus, hectic fever night sweat, dysphoria with feverish sensation in the chest palms and soles, soreness of the waist and knees, and red tongue, few tongue, deep pulse is counted accurately.By Drug therapy of the present invention, oral 3 times/day, 8 grams/times, within 15 days, be 1 course for the treatment of, totally 5 courses for the treatment of, disease is all recovered.Follow up a case by regular visits to 12 months, the state of an illness does not recur.
case 4
Remaining certain, female, 54 years old, peasant, went to a doctor with " sleep disorder ".Medical syndrome: vexedly to sleep less, dry mouth and throat, feverish sensation in the palms and soles, emaciated physique, has a dizzy spell, red tongue, few tongue, thready and rapid pulse.By Drug therapy of the present invention, oral 3 times/day, 8 grams/times, 15 days was 1 course for the treatment of, and disease is all recovered.Follow up a case by regular visits to 12 months, the state of an illness does not recur.

Claims (3)

1. a tranquilizing by nourishing the heart Chinese medicine preparation, by following raw materials by weight portion than making:
Rhizoma Coptidis 15 ~ 20, Colla Corii Asini 15 ~ 20, Radix Bupleuri 15 ~ 20, Fructus Aurantii 15 ~ 20, Pericarpium Citri Reticulatae Viride 15 ~ 20, the Radix Rehmanniae 15 ~ 20, Poria 15 ~ 20, Radix Ophiopogonis 15 ~ 20, Concha Margaritifera 50 ~ 60, Radix Polygalae 15 ~ 20, Semen Ziziphi Spinosae (parched) 50 ~ 60, Dens Draconis 3 ~ 5, succinum 7 ~ 10, Radix Salviae Miltiorrhizae 15 ~ 20, Caulis Polygoni Multiflori 15 ~ 20.
2. a kind of tranquilizing by nourishing the heart Chinese medicine preparation according to claim 1, by following raw materials by weight portion than making:
Rhizoma Coptidis 20, Colla Corii Asini 20, Radix Bupleuri 20, Fructus Aurantii 20, Pericarpium Citri Reticulatae Viride 20, the Radix Rehmanniae 20, Poria 20, Radix Ophiopogonis 20, Concha Margaritifera 60, Radix Polygalae 20, Semen Ziziphi Spinosae (parched) 60, Dens Draconis 5, succinum 10, Radix Salviae Miltiorrhizae 20, Caulis Polygoni Multiflori 20.
3. the preparation method of a kind of tranquilizing by nourishing the heart Chinese medicine preparation described in claim 1 or 2, comprises the following steps:
Take above-mentioned raw materials by weight, after removing foreign material, be ground into 100 ~ 200 order fine powders, obtain final product.
CN201310466044.9A 2013-10-09 2013-10-09 A kind of tranquilizing by nourishing the heart Chinese medicine preparation and preparation method thereof Expired - Fee Related CN103495019B (en)

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CN103750691B (en) * 2014-01-23 2015-05-20 滨州医学院附属医院 Drug pillow for treatment of woman climacteric syndrome
CN105250880A (en) * 2015-11-13 2016-01-20 谭惠娟 Nerve smoothing traditional Chinese medicine composition and preparing method and application thereof
CN105816724A (en) * 2016-05-18 2016-08-03 刘昌红 Traditional Chinese medicine composition for treating female hypersexuality
CN108497100A (en) * 2018-02-22 2018-09-07 安徽中盛食用油科技有限公司 One kind going tired tranquilizing the mind camellia oil and its processing method

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