CN104288379B - Traditional Chinese medicine composition for treating dental ulcer - Google Patents
Traditional Chinese medicine composition for treating dental ulcer Download PDFInfo
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- CN104288379B CN104288379B CN201410511809.0A CN201410511809A CN104288379B CN 104288379 B CN104288379 B CN 104288379B CN 201410511809 A CN201410511809 A CN 201410511809A CN 104288379 B CN104288379 B CN 104288379B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating dental ulcer. The traditional Chinese medicine composition comprises the following raw material medicines in parts by weight: 10-25 parts of radix scrophulariae, 20-50 parts of swimming bladder, 8-15 parts of selfheal, 10-20 parts of lemon slices, 18-25 parts of okra plants, 5-12 parts of aloe, 12-20 parts of gallnut, 1-5 parts of roses, 1-5 parts of Armeniaca mume, 5-15 parts of Pyropolyporus formentarius Teng, 5-10 parts of lotus leaves, 5-10 parts of Bunge Corydalis Herb, 1-5 parts of Radix zanthoxyli and 3-10 parts of liquorice. The various raw material medicines are synergetic and are matched with one another, the effects of removing toxicity for detumescence, clearing internal heat and cooling blood, tretching liver to smooth Qi and astringing to promote granulation and relieve pain are achieved, and after the traditional Chinese medicine composition is taken by patients, the rapid effect of relieving swelling and pain is achieved, the ulcer healing time is short, and the curative effect is obvious.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of oral ulcer, belong to Chinese medicine and preparing technical field thereof.
Background technology
Oral ulcer is a kind of commonly encountered diseases clinically and frequently-occurring disease, with oral mucosa limitation ulcerative lesions for main manifestations, has the feature of recurrent exerbation, causes certain puzzlement to the life of patient.Oral ulcer can occur in any position of oral mucosa, common with the mucosa at the places such as the lip in oral cavity, cheek, soft palate or gums, there is single or multiple circle of differing in size or oval ulcer, greyish white or the yellow pseudomembrane of surface coverage, concavity, clear border, surrounding mucosa is red and micro-swollen, ulcer local causalgia is obvious, has the feature of periodicity, recurrent, self limiting.
The cause of disease of oral ulcer is many-sided, and the regulate factors etc. between the immune state of body, genetic aspect, each tract may be all the pathogenic factor of oral ulcer, and in addition, the environmental factors residing for body also may cause ulcer.The medicine of current treatment oral ulcer has oral medicine and external used medicine, and these medicines respectively have pluses and minuses.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of oral ulcer, said composition is oral drugs, can play the effect relieving the pain, promote ulcer surface to heal of subsiding a swelling fast, taking convenience, evident in efficacy.
The concrete technical scheme of the present invention is as follows:
Treat a Chinese medicine composition for oral ulcer, comprise the crude drug of following weight portion: Radix Scrophulariae 10-25 part, Air Bladder pseudosciaenae seu Acipenser 20-50 part, Spica Prunellae 8-15 part, lemon tablet 10-20 part, Flos abelmoschi manihot Herb 18-25 part, Aloe 5-12 part, Galla Chinensis 12-20 part, Flos Rosae Rugosae 1-5 part, FLOS MUME 1-5 part, Fomes Fomentarius 5-15 part, Folium Nelumbinis 5-10 part, Herba Violae 5-10 part, Radix Zanthoxyli 1-5 part, Radix Glycyrrhizae 3-10 part.
In above-mentioned Chinese medicine composition, preferably include the crude drug of following weight portion: Radix Scrophulariae 20 parts, 30 parts, Air Bladder pseudosciaenae seu Acipenser, Spica Prunellae 10 parts, lemon tablet 15 parts, Flos abelmoschi manihot Herb 20 parts, Aloe 10 parts, Galla Chinensis 15 parts, Flos Rosae Rugosae 2 parts, FLOS MUME 2 parts, Fomes Fomentarius 10 parts, 8 parts, Folium Nelumbinis, Herba Violae 8 parts, Radix Zanthoxyli 3 parts, 5 parts, Radix Glycyrrhizae.
Inventor is for etiological study and obtain above-mentioned formula, and in formula, each crude drug works in coordination with onset, can adjust body internal medium, removes the cause of disease, and accelerate the healing of ulcer, above-mentioned each crude drug effect is as follows:
Radix Scrophulariae, clearing away heat and cooling blood, nourishing YIN to lower pathogenic fire, detoxicating and resolving stagnation of pathogens, for fever of the body, excessive thirst, crimson tongue, speckle, hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, constipation is hindered in Tianjin, puckery dim-sighted, the skin sore of order.
Air Bladder pseudosciaenae seu Acipenser, the kidney invigorating and essence nourishing, nourishing muscle arteries and veins, dissipating blood stasis for subsidence of swelling, hemostasis, skin Caring.
Spica Prunellae, there is the effect of letting out clearly liver-fire, mass dissipating and swelling eliminating, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, cooling blood for hemostasis, be applicable to lymphoid tuberculosis, goiter, acute mastitis, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, metrorrhagia, leukorrhagia, Fiedeler's disease type hepatitis and bacillary dysentery etc.
Lemon tablet, containing saccharide, calcium, phosphorus, ferrum and the multiple nutritional components such as vitamin B1, B2, C, there is toxin expelling, slake thirst and help produce saliva, stomach invigorating, the effect such as pain relieving.
Flos abelmoschi manihot, has another name called swordweed, Abelmoschus esculentus, Radix Solani ferocis, and its Herb comprises the root of Flos abelmoschi manihot, leaf and fruit pod, and Flos abelmoschi manihot is rich in abundant vitamin, has the effect of clearing away heat-damp and promoting diuresis, the liver protecting, skin nutrition.
Aloe, containing compositions such as phenols, aloin, tinctura aloes, organic acid, mucopolysaccharide, vitamin, aminoacid, has the effect of detoxicating, relieving inflammation, stomach invigorating relieving constipation, strengthening vital QI to eliminate pathogenic factors, beauty and skin care.
Galla Chinensis, pathogenic fire reducing of astringing the lung, relieving diarrhea with astringents, arresting sweating stops blooding, and removing dampness sore, for chronic cough of deficiency lung, lung-heat phlegmatic cough, chronic diarrhea chronic dysentery, night sweat, quenches one's thirst, hemorrhoidal bleeding of having blood in stool, traumatic hemorrhage, carbuncle sore tumefacting virus, Skin wet and rotten.
Flos Rosae Rugosae, promoting QI circulation for relieving depression, and blood, pain relieving, for stomachache due to hyperactive liver-QI attacking the stomach, lack of appetite vomiting and nausea, menoxenia, falls and flutters the pain of injury.
FLOS MUME, soothing the liver, stomach function regulating, reduces phlegm, and controls globus hystericus, stomachache due to hyperactive liver-QI attacking the stomach, inappetence, dizzy, scrofula.
Fomes Fomentarius, also known as Pyropolyporus fomentarius (L.ex Fr.) Teng, for the sporophore of On Polyporaceae Fomes fomentarius, in hemispherical, the shape of a hoof or hang bell, stockless, perennial, be born on the broad-leaved trunks such as oak, birch, poplar, willow, Hibiscus syriacus, elm, Cortex Fraxini mandshuricae, pears, Lee, Fructus Mali pumilae or on timber, there is the effect of wind-evil dispelling and cold-evil expelling, relaxing muscles and tendons and activating QI and blood in the collateral, removing food stagnancy blood stasis dispelling.
Folium Nelumbinis, has summer heat relieving and dampness eliminating, spleen invigorating yang invigorating, and effect of dissipating blood stasis hemostasis, cures mainly summer-heat excessive thirst, have a headache dizzy, edema, lack of appetite abdominal distention, dysentery, traumatic blood stasis.
Herba Violae, another name Herba corydalis edulis (Plants of Beijing will, Inner Mongol flora), Peng Shi Herba corydalis edulis (Plants of Beijing will), Bu Shi Herba Violae (northeast medicinal plants figure will) etc.Herba Violae heat-clearing and toxic substances removing, irritated for the high heat of epidemic febrile disease, influenza, infectious hepatitis, nephritis, scrofula, parotitis, furuncle and other pyogenic infection.
Radix Zanthoxyli, promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral, the traumatic injury caused for qi depression to blood stasis, rheumatic arthralgia, stomachache, toothache, venom.
Radix Glycyrrhizae, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of institute's abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Further, Herba Centellae, Fructus Citri Sarcodactylis, Radix Pachyrhizi Erosi leaf, Sanguis Draxonis can also be added in above-mentioned formula, to increase curative effect.Herba Centellae clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling; Fructus Citri Sarcodactylis liver-smoothing, qi-regulating; Radix Pachyrhizi Erosi leaf relieving constipation diuresis, strengthen immunologic function, enhance metabolism; Sanguis Draxonis removing blood stasis and relieving pain, hemostasia and promoting granulation.After adding this 4 taste medical material, the new sub-side of formation is (weight portion): Radix Scrophulariae 10-25 part, Air Bladder pseudosciaenae seu Acipenser 20-50 part, Spica Prunellae 8-15 part, lemon tablet 10-20 part, Flos abelmoschi manihot Herb 18-25 part, Aloe 5-12 part, Galla Chinensis 12-20 part, Flos Rosae Rugosae 1-5 part, FLOS MUME 1-5 part, Fomes Fomentarius 5-15 part, Folium Nelumbinis 5-10 part, Herba Violae 5-10 part, Radix Zanthoxyli 1-5 part, Radix Glycyrrhizae 3-10 part, Herba Centellae 10-20 part, Fructus Citri Sarcodactylis 15-25 part, Radix Pachyrhizi Erosi leaf 20-30 part, Sanguis Draxonis 5-10 part.Be preferably (weight portion): Radix Scrophulariae 20 parts, 30 parts, Air Bladder pseudosciaenae seu Acipenser, Spica Prunellae 10 parts, lemon tablet 15 parts, Flos abelmoschi manihot Herb 20 parts, Aloe 10 parts, Galla Chinensis 15 parts, Flos Rosae Rugosae 2 parts, FLOS MUME 2 parts, Fomes Fomentarius 10 parts, 8 parts, Folium Nelumbinis, Herba Violae 8 parts, Radix Zanthoxyli 3 parts, 5 parts, Radix Glycyrrhizae, Herba Centellae 15 parts, Fructus Citri Sarcodactylis 20 parts, 25 parts, Radix Pachyrhizi Erosi leaf, Sanguis Draxonis 8 parts.
Chinese medicine composition of the present invention is oral drugs, and it can be worn into fine powder and take as powder, also decoction can be become to take with decocting, also can conventionally make the different dosage forms such as granule, capsule, tablet by after the concentration of liquid medicine of water extraction, drying.
Inventor to be caused a disease the cause of disease in conjunction with oral ulcer, through large quantity research and experiment, obtain formula of the present invention, by the coordinated of crude drug each in formula, serve removing toxic substances and promoting subsidence of swelling, the removing heat from blood that relieves inflammation or internal heat, depressed liver-energy dispersing and QI regulating, the pain relieving of convergence granulation promoting effect, patient takes that rear reducing swelling and alleviating pain is quick, healing is short, evident in efficacy.
Detailed description of the invention
Below by specific embodiment, the present invention will be described in detail, it is to be understood that following explanation is only to explain the present invention, do not limit its content.If no special instructions, following raw material medicaments is weight portion.
embodiment 1
Present composition crude drug formula is: Radix Scrophulariae 20 parts, 30 parts, Air Bladder pseudosciaenae seu Acipenser, Spica Prunellae 10 parts, lemon tablet 15 parts, Flos abelmoschi manihot Herb 20 parts, Aloe 10 parts, Galla Chinensis 15 parts, Flos Rosae Rugosae 2 parts, FLOS MUME 2 parts, Fomes Fomentarius 10 parts, 8 parts, Folium Nelumbinis, Herba Violae 8 parts, Radix Zanthoxyli 3 parts, 5 parts, Radix Glycyrrhizae.
Preparation method is: mixed by each crude drug, grind to form fine powder, packs for subsequent use.
embodiment 2
Present composition crude drug formula is: Radix Scrophulariae 10 parts, 50 parts, Air Bladder pseudosciaenae seu Acipenser, Spica Prunellae 8 parts, lemon tablet 20 parts, Flos abelmoschi manihot Herb 18 parts, Aloe 12 parts, Galla Chinensis 12 parts, Flos Rosae Rugosae 5 parts, FLOS MUME 1 part, Fomes Fomentarius 15 parts, 5 parts, Folium Nelumbinis, Herba Violae 10 parts, Radix Zanthoxyli 1 part, 10 parts, Radix Glycyrrhizae.
Preparation method is with embodiment 1.
embodiment 3
Present composition crude drug formula is: Radix Scrophulariae 25 parts, 20 parts, Air Bladder pseudosciaenae seu Acipenser, Spica Prunellae 15 parts, lemon tablet 10 parts, Flos abelmoschi manihot Herb 25 parts, Aloe 5 parts, Galla Chinensis 20 parts, Flos Rosae Rugosae 1 part, FLOS MUME 5 parts, Fomes Fomentarius 5 parts, 10 parts, Folium Nelumbinis, Herba Violae 5 parts, Radix Zanthoxyli 5 parts, 3 parts, Radix Glycyrrhizae.
Preparation method is with embodiment 1.
embodiment 4
Present composition crude drug formula is: Radix Scrophulariae 20 parts, 30 parts, Air Bladder pseudosciaenae seu Acipenser, Spica Prunellae 10 parts, lemon tablet 15 parts, Flos abelmoschi manihot Herb 20 parts, Aloe 10 parts, Galla Chinensis 15 parts, Flos Rosae Rugosae 2 parts, FLOS MUME 2 parts, Fomes Fomentarius 10 parts, 8 parts, Folium Nelumbinis, Herba Violae 8 parts, Radix Zanthoxyli 3 parts, 5 parts, Radix Glycyrrhizae, Herba Centellae 15 parts, Fructus Citri Sarcodactylis 20 parts, 25 parts, Radix Pachyrhizi Erosi leaf, Sanguis Draxonis 8 parts.
Preparation method is with embodiment 1.
embodiment 5
Present composition crude drug formula is: Radix Scrophulariae 10 parts, 50 parts, Air Bladder pseudosciaenae seu Acipenser, Spica Prunellae 8 parts, lemon tablet 20 parts, Flos abelmoschi manihot Herb 18 parts, Aloe 12 parts, Galla Chinensis 12 parts, Flos Rosae Rugosae 5 parts, FLOS MUME 1 part, Fomes Fomentarius 15 parts, 5 parts, Folium Nelumbinis, Herba Violae 10 parts, Radix Zanthoxyli 1 part, 10 parts, Radix Glycyrrhizae, Herba Centellae 10 parts, Fructus Citri Sarcodactylis 25 parts, 20 parts, Radix Pachyrhizi Erosi leaf, Sanguis Draxonis 10 parts.
Preparation method is with embodiment 1.
embodiment 6
Present composition crude drug formula is: Radix Scrophulariae 25 parts, 20 parts, Air Bladder pseudosciaenae seu Acipenser, Spica Prunellae 15 parts, lemon tablet 10 parts, Flos abelmoschi manihot Herb 25 parts, Aloe 5 parts, Galla Chinensis 20 parts, Flos Rosae Rugosae 1 part, FLOS MUME 5 parts, Fomes Fomentarius 5 parts, 10 parts, Folium Nelumbinis, Herba Violae 5 parts, Radix Zanthoxyli 5 parts, 3 parts, Radix Glycyrrhizae, Herba Centellae 20 parts, Fructus Citri Sarcodactylis 15 parts, 30 parts, Radix Pachyrhizi Erosi leaf, Sanguis Draxonis 5 parts.
Preparation method is with embodiment 1.
comparative example
Present composition crude drug formula is: Radix Scrophulariae 5 parts, Spica Prunellae 25 parts, lemon tablet 10 parts, Flos abelmoschi manihot Herb 15 parts, Aloe 20 parts, Galla Chinensis 25 parts, Flos Rosae Rugosae 1 part, Fomes Fomentarius 10 parts, 2 parts, Folium Nelumbinis, Radix Zanthoxyli 8 parts, 5 parts, Radix Glycyrrhizae.
Preparation method is with embodiment 1.
in order to determine therapeutic effect of the present invention, carry out clinical trial, to verify its therapeutic effect for the medicine of embodiment 1,2,4,5 and comparative example gained below.
, case source
Extract from this city large hospital the patient that 615 examples suffer from oral ulcer to test, wherein, man 300 example, female 315 example, the age 10-62 year between, 35.8 years old mean age.Heritability recurrent exerbation patient 275 example, general patient 340 example.Ulcer spot: lip 255 example, buccal 208 example, lingual surface 102 example, palatine 50 example.Patient is all medical in 48h after ulcer morbidity, all with causalgia in various degree, anorexia, sialorrhea, pronounce indistinctly.
, Therapeutic Method
Patient is equally divided into 5 groups, each group patient no difference of science of statistics.Often organizing patient uses the medicine of embodiment 1,2,4,5 and comparative example to treat respectively, and using method is: every day 3 times, each 3g.
, criterion of therapeutical effect
Cure: ulcer heals completely, pain disappears;
Effective: pain is obviously alleviated or disappeared, and ulcer surface reduces over half;
Effective: alleviate in pain 3-4 days or disappear, ulcer surface reduces more than 1/3;
Invalid: pain was alleviated without obvious in 4 days, and ulcer surface reduces below 1/3.
, therapeutic outcome
Continuous treatment is after 6 days, and each group patient ulcer healing situation sees the following form 1.
Treatments period respectively organizes patient, and to cure number as shown in table 2 below:
As can be seen from the above table, the present composition is rapid-action, and treatment time is short, is all better than comparative example compositions.And from therapeutic effect, the compositions therapeutic effect of embodiment 4 is best.
Claims (5)
1. treat a Chinese medicine composition for oral ulcer, it is characterized in that the crude drug comprising following weight portion: Radix Scrophulariae 10-25 part, Air Bladder pseudosciaenae seu Acipenser 20-50 part, Spica Prunellae 8-15 part, lemon tablet 10-20 part, Flos abelmoschi manihot Herb 18-25 part, Aloe 5-12 part, Galla Chinensis 12-20 part, Flos Rosae Rugosae 1-5 part, FLOS MUME 1-5 part, Fomes Fomentarius 5-15 part, Folium Nelumbinis 5-10 part, Herba Violae 5-10 part, Radix Zanthoxyli 1-5 part, Radix Glycyrrhizae 3-10 part.
2. Chinese medicine composition according to claim 1, is characterized in that the crude drug comprising following weight portion: Radix Scrophulariae 20 parts, 30 parts, Air Bladder pseudosciaenae seu Acipenser, Spica Prunellae 10 parts, lemon tablet 15 parts, Flos abelmoschi manihot Herb 20 parts, Aloe 10 parts, Galla Chinensis 15 parts, Flos Rosae Rugosae 2 parts, FLOS MUME 2 parts, Fomes Fomentarius 10 parts, 8 parts, Folium Nelumbinis, Herba Violae 8 parts, Radix Zanthoxyli 3 parts, 5 parts, Radix Glycyrrhizae.
3. Chinese medicine composition according to claim 1, is characterized in that the crude drug also comprising following weight portion: Herba Centellae 10-20 part, Fructus Citri Sarcodactylis 15-25 part, Radix Pachyrhizi Erosi leaf 20-30 part, Sanguis Draxonis 5-10 part.
4. Chinese medicine composition according to claim 1, is characterized in that the crude drug also comprising following weight portion: Herba Centellae 15 parts, Fructus Citri Sarcodactylis 20 parts, 25 parts, Radix Pachyrhizi Erosi leaf, Sanguis Draxonis 8 parts.
5. Chinese medicine composition according to claim 1, is characterized in that: described Chinese medicine composition is oral drugs.
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| CN102274353A (en) * | 2010-06-11 | 2011-12-14 | 刘国钧 | Traditional Chinese preparation for treating ulcers |
| CN103041243A (en) * | 2013-01-29 | 2013-04-17 | 宋小冰 | Traditional Chinese medicine capsule for clearing heat, expelling noxious substances and removing acnes |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102274353A (en) * | 2010-06-11 | 2011-12-14 | 刘国钧 | Traditional Chinese preparation for treating ulcers |
| CN103041243A (en) * | 2013-01-29 | 2013-04-17 | 宋小冰 | Traditional Chinese medicine capsule for clearing heat, expelling noxious substances and removing acnes |
Non-Patent Citations (1)
| Title |
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| 中医药治疗复发性口腔溃疡研究进展;李雨等;《国医论坛》;20071231;第22卷(第4期);55－56 * |
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Effective date of registration: 20201221 Address after: No.31, East 2nd Lane, shanguo South Road, Longquan street, Tengzhou City, Zaozhuang City, Shandong Province Patentee after: Tengzhou Fangguan Enterprise Management Consulting Co.,Ltd. Address before: No. 10-5-202, No. 6666, Waihuan South Road, Shizhong District, Jinan City, Shandong Province Patentee before: Zhou Zhihang |