CN102423367B - Beautifying and blood-activating medicament - Google Patents
Beautifying and blood-activating medicament Download PDFInfo
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- CN102423367B CN102423367B CN 201110413410 CN201110413410A CN102423367B CN 102423367 B CN102423367 B CN 102423367B CN 201110413410 CN201110413410 CN 201110413410 CN 201110413410 A CN201110413410 A CN 201110413410A CN 102423367 B CN102423367 B CN 102423367B
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Abstract
The invention provides a beautifying and blood-activating medicament, which consists of the following components in parts by mass: 200 to 300 parts of Chinese angelica, 200 to 300 parts of white peony root, 200 to 300 parts of bighead atractylodes rhizome, 200 to 300 parts of poria, 20 to 80 parts of safflower, 60 to 100 parts of Chinese honeylocust spine, 200 to 300 parts of bupleurum marginatum, 70 to 100 parts of tree peony root bark, 220 to 260 parts of rehmannia root, 20 to 60 parts of mint, and 165 to 225 parts of liquorice. The medicament is prepared by the following steps: distilling Chinese angelica, bighead atractylodes rhizome and mint to extract volatile oil; decocting medicinal residues together with the other 8 medicinal materials; concentrating to prepare extract; and mixing the extract with the volatile oil. The medicament has the functions of soothing liver, regulating vital energy and activating blood, is used for treating depression of liver and vital energy, distending pain in the chest and hypochondriac regions, light-headedness, anorexia, irregular menstruation, tender breast or with chloasma on face, and has remarkable curative effects of quick recovery, low relapse rate, high safety, no side effect and the like, and has low cost and convenience in preparation.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition---the skin care blood circulation promoting medicine belongs to biological technical field.
Background technology
Liver controlling conveyance and dispersion has the function of turnover QI and blood, and natural disposition just is contrary to, and dislikes the change of depression, and the stimulation of any feelings will all can cause irritability strongly fragrant, and catharsis is not normal and not smooth, the light stagnation of QI then, even QI rising in reverse order, and stagnation of QI QI rising in reverse order can cause blood stasis and blood oozing from the body openings or subcuta neous tissue.Treatment is then take suppressing hyperactive liver for descending adverse qi as main.Three blood stasis, irritability stasis can cause blood stasis.Difficult Classic is said: " liver is long-pending, and name is said lump at the left hypochondrium, under left flank, such as multiple cup, cephalopodium is arranged ... "." have between skin thread red trace person, hematoma is also " that Zhu Danxi mentions, all be say cause the syndrome of the stasis of blood because of the stagnation of QI.Common sign such as hepatosplenomegaly, spider angiomas etc. in hepatopathy all are the results of blood stasis, and treatment is just often take blood circulation promoting and blood stasis dispelling as main.
And modern society, people often because of work and life stress cause depression of liver-QI, the long-term stagnation of QI cause the stasis of blood and with congestion, hemorrhage, menoxenia, dysmenorrhea, depression, have a dizzy spell, the symptoms such as the tired power of body, vomiting, insomnia and dreamful sleep, irritability, appetite are poor, distending pain in the chest and hypochondrium, make troubles for life, work.
Summary of the invention
Cause uncomfortable that the stasis of blood brings for solving the stagnation of QI, the invention provides the Chinese medicine that a kind of skin care is invigorated blood circulation.
The invention provides a kind of skin care blood circulation promoting medicine, it is characterized in that being formed by the component of following mass parts:
200～300 parts of 200～300 portions of Radix Paeoniae Albas of Radix Angelicae Sinensis
200～300 parts in 200～300 parts of Poria of the Rhizoma Atractylodis Macrocephalae
60～100 parts of 20～80 parts of Spina Gleditsiaes of Flos Carthami
70～110 parts of 200～300 parts of Cortex Moutans of HERBA BUPLEURI
20～60 parts of 220～260 portions of Herba Menthaes of the Radix Rehmanniae
165～225 parts in Radix Glycyrrhizae.
The invention provides a kind of skin care blood circulation promoting medicine, the component of preferred following mass parts:
260 parts of 260 portions of Radix Paeoniae Albas of Radix Angelicae Sinensis
260 parts in 260 parts of Poria of the Rhizoma Atractylodis Macrocephalae
80 parts of 50 parts of Spina Gleditsiaes of Flos Carthami
90 parts of 260 parts of Cortex Moutans of HERBA BUPLEURI
40 parts of 240 portions of Herba Menthaes of the Radix Rehmanniae
195 parts in Radix Glycyrrhizae.
Wherein, Radix Angelicae Sinensis: nature and flavor: warm in nature, sweet in the mouth, suffering; Return liver, the heart, spleen channel; Cure mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.The Radix Paeoniae Alba: nature and flavor: picric acid, cold; Enter liver, spleen channel; Cure mainly: nourishing blood for regulating menstruation, easing the affected liver to relieve pain, astringing YIN to stop sweating, suppressing liver-YANG.The Rhizoma Atractylodis Macrocephalae: nature and flavor: bitter, sweet, temperature; Return spleen, stomach warp; Cure mainly: invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.Poria: nature and flavor: sweet, light, flat; GUIXIN warp, lung meridian, spleen channel, kidney channel; Cure mainly: promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Flos Carthami: nature and flavor: warm in nature, acrid in the mouth, GUIXIN, Liver Channel; Cure mainly: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Spina Gleditsiae: nature and flavor: suffering, temperature; Return liver, stomach warp; Cure mainly: swollen ulcer drug, scrofula, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, placenta retention, leprosy.HERBA BUPLEURI: nature and flavor: warm in nature, acrid in the mouth; Enter liver, spleen, bladder three warps; Cure mainly: induce sweat, dispel the wind, win wet.Cortex Moutan: nature and flavor: cold in nature, bitter in the mouth, cold, be slightly cold; GUIXIN, liver, kidney channel; Cure mainly: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.The Radix Rehmanniae: nature and flavor: sweet, cold; GUIXIN, liver, kidney channel; Cure mainly: clearing away heat and cooling blood, yin nourishing is promoted the production of body fluid.Herba Menthae: nature and flavor: suffering, cold; Return lung, Liver Channel; Function: dispelling wind and heat pathogens, clearing throat, rash detoxifcation, dispersing the stagnated live-QI to relieve the stagnation of QI.Radix Glycyrrhizae: nature and flavor: property is flat, and sweet in the mouth is returned 12 warps; Cure mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Each composition of the present invention is the national corporation of medical herbs commercially available prod.
The invention provides the pharmacological action of medicine: Radix Angelicae Sinensis has the merit of enriching blood and invigorating blood circulation; The Radix Paeoniae Alba has the effect of nourishing blood to suppress the hyperactive liver; The Rhizoma Atractylodis Macrocephalae has the effect of invigorating the spleen and benefiting QI, dampness diuretic; Poria has the effect of promoting diuresis to eliminate damp pathogen, mind tranquilizing and the heart calming; Flos Carthami has the merit of the latus rectum of invigorating blood circulation, eliminating stasis to stop pain; Spina Gleditsiae has the effect of invigorating blood circulation, dispeling the wind; HERBA BUPLEURI has the effect of inducing sweat, dispeling the wind; Cortex Moutan has the merit of clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling; The Radix Rehmanniae has the effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; Herba Menthae has the effect of dispersing the stagnated live-QI to relieve the stagnation of QI; Radix Glycyrrhizae has the merit of invigorating the spleen and replenishing QI.
Skin care blood circulation promoting medicine of the present invention makes through following method:
(1) by following mass parts feeding:
200～300 parts of 200～300 portions of Radix Paeoniae Albas of Radix Angelicae Sinensis
200～300 parts in 200～300 parts of Poria of the Rhizoma Atractylodis Macrocephalae
60～100 parts of 20～80 parts of Spina Gleditsiaes of Flos Carthami
70～110 parts of 200～300 parts of Cortex Moutans of HERBA BUPLEURI
20～60 parts of 220～260 portions of Herba Menthaes of the Radix Rehmanniae
165～225 parts in Radix Glycyrrhizae;
(2) Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, Herba Menthae in the step (1) are extracted volatile oil with vapor distillation, volatile oil is for subsequent use; Last medicinal residues and all the other eight flavor medical materials are that 1 ︰ 4～8 decocts with water twice by the solid-liquid mass ratio, each 1～3 hour, the each filtration, the relative density when merging twice filtrate and being concentrated into 50 ℃ is 1.35～1.40 thick paste, mix with volatile oil, namely obtain the Chinese medicine composition that skin care is invigorated blood circulation.
In above-mentioned Chinese medicine composition provided by the invention, add an amount of adjuvant commonly used, such as starch and magnesium stearate etc., make pharmaceutically acceptable any preparation by conventional method of the prior art, such as preparations such as tablet, decoction, capsule, soft capsule, dissolved granule, pill, oral liquids.
The effect that the present invention possesses and advantage:
Skin care blood circulation promoting medicine provided by the invention, the effect of have soothing liver-QI, regulate the flow of vital energy, invigorating blood circulation; Be used for depression of liver-QI, distending pain in the chest and hypochondrium is had a dizzy spell, loss of appetite, and menoxenia, distending pain of the breast or companion see the face chloasma.And have the significant curative effects such as recovery is fast, relapse rate is low, safe, have no side effect, and cost is low, simple for production.
Description of drawings
The effective percentage figure of Fig. 1 symptom that to be skin care blood circulation promoting medicine provided by the invention cause depression of liver-QI.
The specific embodiment
Further illustrate content of the present invention below in conjunction with embodiment, but protection scope of the present invention is not limited in these embodiment.
Embodiment 1
(1) by following mass parts feeding:
260 parts of 260 portions of Radix Paeoniae Albas of Radix Angelicae Sinensis
260 parts in 260 parts of Poria of the Rhizoma Atractylodis Macrocephalae
80 parts of 50 parts of Spina Gleditsiaes of Flos Carthami
90 parts of 260 parts of Cortex Moutans of HERBA BUPLEURI
40 parts of 240 portions of Herba Menthaes of the Radix Rehmanniae
195 parts in Radix Glycyrrhizae;
(2) Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, Herba Menthae in the step (1) are extracted volatile oil with vapor distillation, volatile oil is for subsequent use; Last medicinal residues and all the other eight flavor medical materials are that 1 ︰ 6 decocts with water twice by the solid-liquid mass ratio, and each 2 hours, the each filtration, merging twice filtrate and being concentrated into relative density was 1.40(50 ℃) thick paste, mix with volatile oil, namely obtain the skin care blood circulation promoting medicine.
In said medicine, add appropriate amount of starch, magnesium stearate, make tablet by conventional method of the prior art.Contain the Radix Paeoniae Alba in every with peoniflorin (C
23H
28O
11) meter, must not be less than 1.50mg.
Embodiment 2
(1) by following mass parts feeding:
300 parts of 200 portions of Radix Paeoniae Albas of Radix Angelicae Sinensis
300 parts in 200 parts of Poria of the Rhizoma Atractylodis Macrocephalae
60 parts of 80 parts of Spina Gleditsiaes of Flos Carthami
110 parts of 200 parts of Cortex Moutans of HERBA BUPLEURI
20 parts of 260 portions of Herba Menthaes of the Radix Rehmanniae
225 parts in Radix Glycyrrhizae;
(2) Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, Herba Menthae in the step (1) are extracted volatile oil with vapor distillation, volatile oil is for subsequent use; Last medicinal residues and all the other eight flavor medical materials are that 1 ︰ 4 decocts with water twice by the solid-liquid mass ratio, and each 3 hours, the each filtration, merging twice filtrate and being concentrated into relative density was 1.38(50 ℃) thick paste, mix with volatile oil, namely obtain the skin care blood circulation promoting medicine.
Embodiment 3
(1) by following mass parts feeding:
200 parts of 300 portions of Radix Paeoniae Albas of Radix Angelicae Sinensis
200 parts in 300 parts of Poria of the Rhizoma Atractylodis Macrocephalae
100 parts of 20 parts of Spina Gleditsiaes of Flos Carthami
70 parts of 300 parts of Cortex Moutans of HERBA BUPLEURI
60 parts of 220 portions of Herba Menthaes of the Radix Rehmanniae
165 parts in Radix Glycyrrhizae;
(2) Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, Herba Menthae in the step (1) are extracted volatile oil with vapor distillation, volatile oil is for subsequent use; Last medicinal residues and all the other eight flavor medical materials are that 1 ︰ 8 decocts with water twice by the solid-liquid mass ratio, and each 1 hour, the each filtration, merging twice filtrate and being concentrated into relative density was 1.35(50 ℃) thick paste, mix with volatile oil, namely obtain the skin care blood circulation promoting medicine.
Pharmacology's toxicologic study of the Chinese medicine composition of skin care blood circulation promoting medicine provided by the invention:
When giving rat with 20g/kg, 10g/kg, 5g/kg, give continuously rats gavaged after 90 days, GPT, GOT, BUN, G are all without unusual in animal general activity, body weight, blood hemoglobin, leukocyte, erythrocyte, platelet, leukocyte differential count, the blood, with normal saline group there was no significant difference, its numerical value is all in normal range, the main organs such as rats'liver, spleen, lung, kidney, intestinal, brain, testis, ovary are also had no adverse effects, i.e. the Chinese medicine composition clinical practice that skin care is invigorated blood circulation safely, have no side effect.
Get the Chinese medicine composition of above-described embodiment 1 gained skin care blood circulation promoting medicine, be used for following clinical treatment:
One, treatment target
The menoxenia, distending pain of the breast, distending pain in the chest and hypochondrium 300 examples that cause because of liver qi stagnation type, and with have a dizzy spell, the symptom such as inappetence, depression of liver-QI, face chloasma, be divided at random treatment group and matched group each 150 examples, wherein menoxenia 50 examples, distending pain of the breast 50 examples, distending pain in the chest and hypochondrium 50 examples.
Two, instructions of taking
Treatment group is oral, each 2～4,3 times on the one, serve on 21.
Matched group is taken conventional soothing liver-QI medicine routinely, serve on 21.
Three, result:
The Chinese medicine clinical therapeutic efficacy of skin care blood circulation promoting medicine provided by the invention is seen Fig. 1, the effective percentage of the menoxenia that depression of liver-QI is caused reaches 96%, the effective percentage of distending pain of the breast reaches 93%, the effective percentage of distending pain in the chest and hypochondrium reaches 89%, and the effective percentage of the menoxenia that matched group causes depression of liver-QI only reaches 60%, the effective percentage of distending pain of the breast reaches 50%, the effective percentage of distending pain in the chest and hypochondrium reaches 43%.
Four, conclusion
The Chinese medicine composition of skin care blood circulation promoting medicine provided by the invention be by HERBA BUPLEURI, Radix Angelicae Sinensis, the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae, Poria, Spina Gleditsiae, Cortex Moutan, the Radix Rehmanniae, Flos Carthami, Herba Menthae, Radix Glycyrrhizae preparation and compound preparation, the menoxenia that liver qi stagnation type is caused, distending pain in the chest and hypochondrium, significant curative effect is arranged, can improve cerebral tissue, cardiac muscle suppresses thrombotic effect in the experimental animals in addition to the impaired power of anoxia, and its effect of menoxenia is better than matched group.
The Chinese medicine composition that this skin care is invigorated blood circulation is according to Yi nationality of Yunnan traditional medicine document " sorrow jail book on Chinese herbal medicine ", on the basis of traditional Chinese medical science ancient prescription " XIAOYAO POWDER " (Song " formulary of peaceful benevolent dispensary "), in conjunction with Ailaoshan mountain area Yi nationality, distributed over Yunnan, Sichuan and Guizhou folk medicine experience, the pure natural ethnic drug that develops through scientific composition, through over thousands of routine clinical verification, this Chinese medicine composition is the good medicine of regulating women's endocrine, has soothing liver-QI, regulate the flow of vital energy, the effect of invigorating blood circulation, to depression of liver-QI, distending pain in the chest and hypochondrium, have a dizzy spell, loss of appetite, menoxenia, distending pain of the breast or face chloasma have significant curative effect, the menoxenia for the treatment of gynecological, the good medicine of distending pain of the breast disease.
The advantage such as effective in cure good, the application safety of the Chinese medicine composition of this skin care blood circulation promoting medicine, toxic and side effects are little, prepared constant product quality, easy to use, be more suitable in clinical application.
Claims (2)
1. skin care blood circulation promoting medicine is characterized in that being made by the component of following mass parts:
200～300 parts of 200～300 portions of Radix Paeoniae Albas of Radix Angelicae Sinensis
200～300 parts in 200～300 parts of Poria of the Rhizoma Atractylodis Macrocephalae
60～100 parts of 20～80 parts of Spina Gleditsiaes of Flos Carthami
70～110 parts of 200～300 parts of Cortex Moutans of HERBA BUPLEURI
20～60 parts of 220～260 portions of Herba Menthaes of the Radix Rehmanniae
165～225 parts in Radix Glycyrrhizae.
2. the method for preparing the described skin care blood circulation promoting medicine of claim 1 is characterized in that through following each step:
(1) by following mass parts feeding:
200～300 parts of 200～300 portions of Radix Paeoniae Albas of Radix Angelicae Sinensis
200～300 parts in 200～300 parts of Poria of the Rhizoma Atractylodis Macrocephalae
60～100 parts of 20～80 parts of Spina Gleditsiaes of Flos Carthami
70～110 parts of 200～300 parts of Cortex Moutans of HERBA BUPLEURI
20～60 parts of 220～260 portions of Herba Menthaes of the Radix Rehmanniae
165～225 parts in Radix Glycyrrhizae;
(2) Radix Angelicae Sinensis in the step (1), the Rhizoma Atractylodis Macrocephalae, Herba Menthae are extracted volatile oil with vapor distillation for subsequent use; Last medicinal residues and all the other eight flavor medical materials are 1 ︰ 4～8 by the solid-liquid mass ratio, decoct with water twice, each 1～3 hour, the each filtration, relative density when merging twice filtrate and being concentrated into 50 ℃ is 1.35～1.40 thick paste, mixes with volatile oil, namely obtains the Chinese medicine composition that skin care is invigorated blood circulation.
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