CN104146244A - Acanthopanax root and boschniakia rossica oral solution and preparation method thereof - Google Patents

Acanthopanax root and boschniakia rossica oral solution and preparation method thereof Download PDF

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Publication number
CN104146244A
CN104146244A CN201410331066.9A CN201410331066A CN104146244A CN 104146244 A CN104146244 A CN 104146244A CN 201410331066 A CN201410331066 A CN 201410331066A CN 104146244 A CN104146244 A CN 104146244A
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parts
old
extractor
ultramicro
acanthopanax root
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CN201410331066.9A
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CN104146244B (en
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崔永坤
崔永佶
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TONGHUA XINDONGRI PHARMACEUTICAL CO., LTD.
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TONGHUA SANLI HEALTH Co Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L21/00Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
    • A23L21/20Products from apiculture, e.g. royal jelly or pollen; Substitutes therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention discloses an acanthopanax root and boschniakia rossica oral solution which comprises the following raw materials in parts by weight: 300-500 parts of acanthopanax root seed, 80-120 parts of boschniakia rossica, 600-800 parts of water and 80-120 parts of linden royal jelly. The acanthopanax root and boschniakia rossica oral solution is prepared by adopting the steps: drying the acanthopanax root seed and the boschniakia rossica, breaking walls to obtain ultramicro-pulverized powder, extracting with ethanol, and concentrating to prepare an acanthopanax root and boschniakia rossica extract paste; adding high-quality Changbai mountain spring water and a defined amount of linden royal jelly, and uniformly stirring to obtain the acanthopanax root and boschniakia rossica oral solution. The acanthopanax root and boschniakia rossica oral solution has the functions of improving the metabolism, promoting nutrient uptake, enhancing the immunologic function of a human body, resisting fatigue and ageing, nourishing the nerves, and the like. The acanthopanax root and boschniakia rossica oral solution disclosed by the invention is simple in preparation process, and suitable for industrialized production.

Description

A kind of wilsonii is old careless oral liquid and preparation method thereof not
Technical field
The present invention relates to health food technology field.More specifically, relate to not old careless oral liquid and preparation method thereof of a kind of wilsonii.
Background technology
At present, the diseases such as hypertension, high fat of blood, cerebral thrombus, neurasthenia, early ageing have had generality, serious harm is healthy, even cause the life-threatening major diseases such as diabetes, cerebral thrombus, myocardial infarction, tumour, leukaemia, caused thus prevention from suffering from the diseases and treatment are paid much attention to.Put prevention first and extensively praised highly always, therefore, develop high-end health food, regulate in time sub-health population, the auxiliary sufferer illness of alleviating, is of great immediate significance.
Motherland's medicine and pharmacology are of extensive knowledge and profound scholarship, and Chinese medicine is of a great variety, and Changbaishan area, northeast wilsonii is the good medicine of health care.Wilsonii is regarded as having the good medicine that adds essence benefit marrow and anti-aging effects from ancient times, < < Compendium of Materia Medica > > claim wilsonii, good with the five leaf persons of accompanying each other, therefore named slender acanthopanax, has another name called five flowers.Slender acanthopanax is controlled rheumatism, strengthens the bone, and its merit is good dark.And northern wilsonii is best in quality, adrenal gland is had to good effect, can strengthen the disease ability of resisting; Eleutheroside can improve acuity and physics endurance, siberian Ginseng P.E shows can irritation cell immunity, Cure of depression, cerebral thrombus, high fat of blood, hypertension, coronary heart disease, diabetes, leukopenia etc., also helpful to the AIDS treatment of commitment; The not old grass in Changbai Mountain is distinctive plant, and not old grass has another name called broomrape, angiosperm, and the orchid family, is grown on the cliff or steep cliff of height above sea level 1300-2000 rice, has now realized artificial culture.All herbal medicine, contains the super kinases of a large amount of CR, and the special effect that have tonifying kidney and strengthening yang, relaxes bowel cures mainly impotence due to deficiency of the kidney, waist knee skelagia, the dry constipation of intestines and cystitis etc., and popular legend has effect alive for evermore, and " not old grass " gains the name thus; Changbai Mountain royal jelly is gone through the differentiation of thousands of years, in the Qing Dynasty, gain the name, for imperial palace tribute, the woodsy extraordinary royal jelly of natural linden on Changbai Mountain, mainly contains protein, fat, carbohydrate, vitamin A, Cobastab l, vitamin B2, abundant folic acid, pantothenic acid and inositol.Also have similar acetylcholine sample material, and the amino acid of multiple human body needs and bio-hormone etc.Royal jelly is rich in estrogen for beauty treatment, and menopause symptom is weak after being ill; Infantile malnutrition; Old body declines; Leukopenia; Delay property and chronic hepatitis; Duodenal ulcer; Bronchial astehma; Diabetes; Blood disease; Mental disease; Essential uterine bleeding; Irregular menstruation; Functional sterility and baldness etc.
But, product and the preparation method that the not old careless effect of wilsonii can be given full play to that a kind of mouthfeel is good need to be provided at present.
Summary of the invention
First technical problem that the present invention will solve is to provide the not old careless oral liquid of a kind of wilsonii, and this oral liquid has the metabolism of improvement, promotes nutrient absorption, strengthens immune function of human body, and antifatigue is anti-ageing, the effects such as trophic nerve.
Second technical problem that the present invention will solve is to provide the not preparation method of old careless oral liquid of a kind of wilsonii, and the method preparation technology is simple, and suitability for industrialized is produced.
For solving above-mentioned first technical problem, the present invention adopts following technical proposals:
The not old careless oral liquid of wilsonii, comprises the raw material of following weight fraction: 80~120 parts of 300~500 parts of Radix Et Caulis Acanthopanacis Senticosi seeds, 80~120 parts of old grass, 600~800 parts, water and lime tree royal jelly.
Preferably, described wet concentration is from Changbai Mountain mineral water; Described lime tree royal jelly is selected from Changbai Mountain lime tree royal jelly.
For solving above-mentioned second technical problem, the present invention adopts following technical proposals:
Wilsonii is a preparation method for old careless oral liquid not, comprises following preparation process:
(1) by mass fraction, by being ground into granularity with broken wall equipment after 300~500 parts of Radix Et Caulis Acanthopanacis Senticosi seeds and 80~120 parts of old grass oven dry, be the Ultramicro-powder that 1000~1500 object Radix Et Caulis Acanthopanacis Senticosi seeds mix with old grass;
(2) Ultramicro-powder step (1) being obtained adds in multi-functional extraction thickener group extractor, adding concentration is the ethanol of 60-80%, amount of alcohol added is 8~10 times of Ultramicro-powder quality, the heating of unlatching extractor, extract was heated to seethe with excitement after 20~30 minutes, with suction filtering tube by the extract suction concentration tank of 20-40%;
It is 70~85 ℃ that unlatching concentration tank and heating system make concentrate temperature, and vacuum is-0.05~-0.08MPa, until be condensed into Radix Et Caulis Acanthopanacis Senticosi seed, not old careless cream, in cream, moisture content is 25~30%;
(3) in the slender acanthopanax seed obtaining in step (2), not old careless cream, add 600~800 parts of pure water, 80~120 parts of lime tree royal jelly, after stirring, obtain the not old careless oral liquid of product wilsonii in mixer.
Preferably, the indirect steam producing when the described concentration tank of step (2) is concentrated becomes condensate liquid through condenser and cooler and is back to extractor and re-uses as solvent, solvent from top to bottom arrives extractor bottom by Ultramicro-powder, soluble component in Ultramicro-powder is dissolved in extractor internal solvent, extract is through suction filtering tube suction concentration tank, the concentrated indirect steam producing is delivered to again extractor and is done novel solvent, formation solvent refluxing extracts, until completely stripping to be that extracting liquid colourless is concentrated proceed, the colourless liquid in extractor reclaims for reusing next time.
Beneficial effect of the present invention is as follows:
In the not old careless oral liquid of wilsonii of the present invention, isofraxidin is up to 66.57%, and eleutheroside content can reach more than 65%, and Radix Et Caulis Acanthopanacis Senticosi polysaccharide content is up to 73.9%; The present invention utilizes rupture of membranes wall breaking technology that cell membrane is smashed and allowed effective component discharge, the super kinases content of not old careless CR 200Wan unit, and absorptivity can be up to 95%; The super nutritive food royal jelly and the mineral water that add fresh high activity composition, pure natural, preservative free, highly extract raw material beneficiating ingredient, avoided the waste of the existing mode of production to valuable ingredient of traditional Chinese medicine drug effect, also reduced production cost, and benefited the edible crowd of health products simultaneously.
The specific embodiment
In order to be illustrated more clearly in the present invention, below in conjunction with preferred embodiment, the present invention is described further.It will be appreciated by those skilled in the art that specifically described content is illustrative and nonrestrictive below, should not limit the scope of the invention with this.
Embodiment 1
(1) by mass fraction, by being ground into granularity with broken wall equipment after 300g Radix Et Caulis Acanthopanacis Senticosi seed and the old grass oven dry of 80g, be the Ultramicro-powder that 1000 object Radix Et Caulis Acanthopanacis Senticosi seeds mix with old grass;
(2) Ultramicro-powder step (1) being obtained adds in multi-functional extraction thickener group extractor, adding concentration is 60% ethanol, amount of alcohol added is 8 times of Ultramicro-powder quality, the heating of unlatching extractor, extract was heated to seethe with excitement after 20 minutes, with suction filtering tube by 20% extract suction concentration tank;
It is 70 ℃ that unlatching concentration tank and heating system make concentrate temperature, and vacuum is-0.05~-0.08MPa, until be condensed into Radix Et Caulis Acanthopanacis Senticosi seed, not old careless cream, in cream, moisture content is 25%;
(3) in the slender acanthopanax seed obtaining in step (2), not old careless cream, add Changbai Mountain mineral water 600g, lime tree royal jelly 80g, after stirring, obtain the not old careless oral liquid of product wilsonii in mixer.
The oral liquid that example 1 is made carries out antifatigue and immunity test, with KM small white mouse, for feeding experimental subjects, by Jilin University's preclinical medicine institute zoopery center, is provided, 16 of the healthy mouse of 22-24g, each 8 of male and female, divide four groups, and two female two heros are one group.Feed one time 2ml first group of every day; Feed twice second group of every day, each 2ml; Feed twice the 3rd group of every day, each 5ml; Will not feed for the 4th group.In (20 ± 3) ℃ constant temperature indoor feeding 20 days.
One, anti-fatigue test
1, swimming with a load attached to the body
Four groups of mouse are tied up and using lead as heavy burden at afterbody by 10% of body weight, and the circular channels that then mouse is placed in to 25 ℃ of depth of water 30cm, water temperature is swum; From mouse, sink under the water and within 10 seconds, start to record each mouse swimming time, relatively each group, with the difference of control group, sees the following form:
2, run and test
Four groups of mouse are placed in to rotary animal used as test cage, record mouse run the time and and rest number of times, the results are shown in following table:
Two, immunity experiment
Influenza virus to four groups of injected in mice 0.1ml after first experiment, observes the performance of mouse, the results are shown in following table:
Embodiment 2
(1) by mass fraction, by being ground into granularity with broken wall equipment after 500 parts of Radix Et Caulis Acanthopanacis Senticosi seeds and 120 parts of old grass oven dry, be the Ultramicro-powder that 1500 object Radix Et Caulis Acanthopanacis Senticosi seeds mix with old grass;
(2) Ultramicro-powder step (1) being obtained adds in multi-functional extraction thickener group extractor, adding concentration is 80% ethanol, amount of alcohol added is 10 times of Ultramicro-powder quality, the heating of unlatching extractor, extract was heated to seethe with excitement after 30 minutes, with suction filtering tube by 40% extract suction concentration tank;
It is 85 ℃ that unlatching concentration tank and heating system make concentrate temperature, and vacuum is-0.08MPa that, until be condensed into Radix Et Caulis Acanthopanacis Senticosi seed, not old careless cream, in cream, moisture content is 30%;
(3) in the slender acanthopanax seed obtaining in step (2), not old careless cream, add 800 parts of mineral waters, 120 parts of lime tree royal jelly, after stirring, obtain the not old careless oral liquid of product wilsonii in mixer.
The not old careless oral liquid of the product wilsonii of embodiment 2 is carried out to component content test, and wherein Determination of isofraxidin is 66.57%, and eleutheroside content is 68%, and Radix Et Caulis Acanthopanacis Senticosi polysaccharide content is 73.9%; The super kinases content of not old careless CR 200Wan unit, absorptivity is 95%.
Embodiment 3
(1) by mass fraction, by being ground into granularity with broken wall equipment after 400 parts of Radix Et Caulis Acanthopanacis Senticosi seeds and 100 parts of old grass oven dry, be the Ultramicro-powder that 1200 object Radix Et Caulis Acanthopanacis Senticosi seeds mix with old grass;
(2) Ultramicro-powder step (1) being obtained adds in multi-functional extraction thickener group extractor, adding concentration is 70% ethanol, amount of alcohol added is 8~10 times of Ultramicro-powder quality, the heating of unlatching extractor, extract was heated to seethe with excitement after 25 minutes, with suction filtering tube by 30% extract suction concentration tank;
It is 80 ℃ that unlatching concentration tank and heating system make concentrate temperature, and vacuum is-0.06MPa that, until be condensed into Radix Et Caulis Acanthopanacis Senticosi seed, not old careless cream, in cream, moisture content is 28%;
(3) in the slender acanthopanax seed obtaining in step (2), not old careless cream, add 700 parts of pure water, 100 parts of lime tree royal jelly, after stirring, obtain the not old careless oral liquid of product wilsonii in mixer.
The not old careless oral liquid of the product wilsonii of embodiment 3 is tested, and wherein Determination of isofraxidin is 67%, and eleutheroside content is 65%, and Radix Et Caulis Acanthopanacis Senticosi polysaccharide content is 74%; The super kinases content of not old careless CR 200Wan unit, absorptivity is 95%.
Embodiment 4
Step 1: Radix Et Caulis Acanthopanacis Senticosi seed, not old careless 800g after clear water washing are proceeded to Chinese herbal medicine drying baker, mass percent is that Radix Et Caulis Acanthopanacis Senticosi seed 80%, not old grass 20% are dried, again material is inserted to broken wall equipment (Jinan Yin Run YR-8 type), after 50 minutes, be ground into granularity 1000-1500 object Ultramicro-powder 500-600g;
Step 2: utilize multi-functional herbal medicine to extract concentrated unit and extract concentrated (Shanghai brightness exhibition HZ-TNG), take out step 1 Ultramicro-powder and insert in extractor, adding 8-10 times of concentration is 66% ethanol.Open extractor heating system, make extract be heated to seethe with excitement after 20-30 minute, with suction filtering tube by 1/3rd extract suction concentration tank.Closing extractor directly unites and chuck hot water, unlatching concentration tank is directly united and is made inspissated juice temperature remain on 80 ℃ of left and right with heating system, vacuum keep is at-0.05 arrive-0.08MPA, the indirect steam producing when concentrated becomes condensate liquid through condenser and cooler and is back to extractor and does novel solvent and add, novel solvent from top to bottom arrives extractor bottom by Ultramicro-powder, soluble component in Ultramicro-powder is dissolved in extractor internal solvent, extract is through suction filtering tube suction concentration tank, the concentrated indirect steam producing is delivered to again extractor and is done novel solvent, form novel solvent refluxing extraction, until stripping (extracting liquid colourless) is concentrated completely, proceed, until be condensed into Radix Et Caulis Acanthopanacis Senticosi seed, not old careless cream, moisture in cream is 25-30%, colourless liquid in extractor can be next multiplexing.
Step 3: step 2 gained slender acanthopanax seed, not old careless cream are added to high-quality Changbai Mountain mineral spring pure water, Changbai Mountain lime tree royal jelly, filling to the aseptic vial of 10ml after stirring in mixer.Mass percent is slender acanthopanax seed and not old careless cream 40%, purified water 50%, royal jelly 10%.
Embodiment 5
Identical with embodiment 4 methods, difference is that mass percent is slender acanthopanax seed, not old careless cream 35%, purified water 50%, royal jelly 15%.
Product prepared by embodiment 5 is to sub-health population; 10 adults of physique deviation take, eating method and amount: every day 2 times, each 1 bottle.
After one month, all reflect that this oral liquid mouthfeel is good, can effectively improve metabolism, promote nutrient absorption, promote hematopoiesis, strengthen immune function of human body, antifatigue, anti-ageing, trophic nerve, balancing blood fat, blood pressure, blood sugar, get well.
Comparative example 1
With embodiment 1, its difference is only: it is 1000 object Radix Et Caulis Acanthopanacis Senticosi seed Ultramicro-powders that step (1) is ground into granularity with broken wall equipment after 380g Radix Et Caulis Acanthopanacis Senticosi seed being dried by mass fraction.
Comparative example 2
With embodiment 1, its difference is only: it is the Ultramicro-powder that the not old grass of 1000 objects mixes that step (1) is ground into granularity with broken wall equipment after the not old grass of 380g being dried by mass fraction.
The product of comparative example 1,2 and embodiment 1 is used for to sub-health population; 10 adults of physique deviation take, eating method and amount: every day 2 times, each 1 bottle.
The products taste of embodiment 1 is good, can effectively improve metabolism, promotes nutrient absorption, promotes hematopoiesis, strengthens immune function of human body, and antifatigue is anti-ageing, trophic nerve, and balancing blood fat, blood pressure, blood sugar, get well.
The products taste of comparative example 1,2 is general, and sub-health state does not improve.
The consumption that increases the product of comparative example 1,2 is every day 3 times, each 2 bottles, only can balancing blood fat, blood pressure, blood sugar, and to strengthening immune function of human body, antifatigue, anti-ageing, trophic nerve does not have clear improvement.
Obviously; the above embodiment of the present invention is only for example of the present invention is clearly described; and be not the restriction to embodiments of the present invention; for those of ordinary skill in the field; can also make other changes in different forms on the basis of the above description; here cannot give all embodiments exhaustive, every still row in protection scope of the present invention of apparent variation that technical scheme of the present invention extends out or change that belong to.

Claims (4)

1. the not old careless oral liquid of wilsonii, is characterized in that, comprises the raw material of following weight fraction: 80~120 parts of 300~500 parts of Radix Et Caulis Acanthopanacis Senticosi seeds, 80~120 parts of old grass, 600~800 parts, water and lime tree royal jelly.
2. the not old careless oral liquid of wilsonii according to claim 1, is characterized in that: described wet concentration is from Changbai Mountain mineral water; Described lime tree royal jelly is selected from Changbai Mountain lime tree royal jelly.
3. the wilsonii as claimed in claim 1 or 2 preparation method of old careless oral liquid not, is characterized in that, comprises following preparation process:
(1) by mass fraction, by being ground into granularity with broken wall equipment after 300~500 parts of Radix Et Caulis Acanthopanacis Senticosi seeds and 80~120 parts of old grass oven dry, be the Ultramicro-powder that 1000~1500 object Radix Et Caulis Acanthopanacis Senticosi seeds mix with old grass;
(2) Ultramicro-powder step (1) being obtained adds in multi-functional extraction thickener group extractor, adding concentration is the ethanol of 60-80%, amount of alcohol added is 8~10 times of Ultramicro-powder quality, the heating of unlatching extractor, extract was heated to seethe with excitement after 20~30 minutes, with suction filtering tube by the extract suction concentration tank of 20-40%;
It is 70~85 ℃ that unlatching concentration tank and heating system make concentrate temperature, and vacuum is-0.05~-0.08MPa, until be condensed into Radix Et Caulis Acanthopanacis Senticosi seed, not old careless cream, in cream, moisture content is 25~30%;
(3) in the slender acanthopanax seed obtaining in step (2), not old careless cream, add 600~800 parts, water, 80~120 parts of lime tree royal jelly, after stirring, obtain the not old careless oral liquid of product wilsonii in mixer.
4. the wilsonii according to claim 1 preparation method of old careless oral liquid not, it is characterized in that: the indirect steam producing when the described concentration tank of step (2) is concentrated becomes condensate liquid through condenser and cooler and is back to extractor and re-uses as solvent, solvent from top to bottom arrives extractor bottom by Ultramicro-powder, soluble component in Ultramicro-powder is dissolved in extractor internal solvent, extract is through suction filtering tube suction concentration tank, the concentrated indirect steam producing is delivered to again extractor and is done novel solvent, formation solvent refluxing extracts, until completely stripping to be that extracting liquid colourless is concentrated proceed, colourless liquid in extractor reclaims for reusing next time.
CN201410331066.9A 2014-07-11 2014-07-11 Not old careless oral liquid of a kind of wilsonii and preparation method thereof Active CN104146244B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104544427A (en) * 2014-12-18 2015-04-29 安徽博格生物科技有限公司 Beauty and health beverage capable of delaying senescence and resisting oxidation

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CN101744070A (en) * 2010-03-18 2010-06-23 邵伟 Slender acanthopanax boschniakia rossica black tea
CN102068586A (en) * 2011-01-03 2011-05-25 山东大学威海分校 Preparation method and application of composite Chinese magnoliavine fruit preparation
CN103535728A (en) * 2013-10-25 2014-01-29 华霄鸢 Formula as well as preparation method of efficient accumulation-eliminating, stasis-dissipating, detoxifying, beautifying and health-maintaining health-care product

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CN101744070A (en) * 2010-03-18 2010-06-23 邵伟 Slender acanthopanax boschniakia rossica black tea
CN102068586A (en) * 2011-01-03 2011-05-25 山东大学威海分校 Preparation method and application of composite Chinese magnoliavine fruit preparation
CN103535728A (en) * 2013-10-25 2014-01-29 华霄鸢 Formula as well as preparation method of efficient accumulation-eliminating, stasis-dissipating, detoxifying, beautifying and health-maintaining health-care product

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104544427A (en) * 2014-12-18 2015-04-29 安徽博格生物科技有限公司 Beauty and health beverage capable of delaying senescence and resisting oxidation

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