CN104024406A - 液体酶制剂及其制备方法 - Google Patents
液体酶制剂及其制备方法 Download PDFInfo
- Publication number
- CN104024406A CN104024406A CN201280053784.3A CN201280053784A CN104024406A CN 104024406 A CN104024406 A CN 104024406A CN 201280053784 A CN201280053784 A CN 201280053784A CN 104024406 A CN104024406 A CN 104024406A
- Authority
- CN
- China
- Prior art keywords
- transglutaminase
- enzyme
- preparation
- suspension
- polyol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/06—Enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0055—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
- C12N9/0057—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
- C12N9/0059—Catechol oxidase (1.10.3.1), i.e. tyrosinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0055—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
- C12N9/0057—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
- C12N9/0061—Laccase (1.10.3.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y110/00—Oxidoreductases acting on diphenols and related substances as donors (1.10)
- C12Y110/03—Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
- C12Y110/03001—Catechol oxidase (1.10.3.1), i.e. tyrosinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y110/00—Oxidoreductases acting on diphenols and related substances as donors (1.10)
- C12Y110/03—Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
- C12Y110/03002—Laccase (1.10.3.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/02—Aminoacyltransferases (2.3.2)
- C12Y203/02013—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
- C12Y305/01043—Peptidyl-glutaminase (3.5.1.43)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810281980.5A CN108676782A (zh) | 2011-11-01 | 2012-10-31 | 液体酶制剂及其制备方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20116074 | 2011-11-01 | ||
| FI20116074A FI126442B (en) | 2011-11-01 | 2011-11-01 | Liquid enzyme preparation and process for its preparation |
| PCT/FI2012/051048 WO2013064736A1 (en) | 2011-11-01 | 2012-10-31 | A liquid enzyme formulation and a process for its preparation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810281980.5A Division CN108676782A (zh) | 2011-11-01 | 2012-10-31 | 液体酶制剂及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104024406A true CN104024406A (zh) | 2014-09-03 |
Family
ID=47215584
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280053784.3A Pending CN104024406A (zh) | 2011-11-01 | 2012-10-31 | 液体酶制剂及其制备方法 |
| CN201810281980.5A Pending CN108676782A (zh) | 2011-11-01 | 2012-10-31 | 液体酶制剂及其制备方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810281980.5A Pending CN108676782A (zh) | 2011-11-01 | 2012-10-31 | 液体酶制剂及其制备方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20140287098A1 (https=) |
| EP (1) | EP2773753B1 (https=) |
| JP (1) | JP6297979B2 (https=) |
| KR (1) | KR101998182B1 (https=) |
| CN (2) | CN104024406A (https=) |
| AU (1) | AU2012331034B2 (https=) |
| BR (1) | BR112014010222B1 (https=) |
| CA (1) | CA2853711C (https=) |
| CL (1) | CL2014001100A1 (https=) |
| DK (1) | DK2773753T3 (https=) |
| ES (1) | ES2697675T3 (https=) |
| FI (1) | FI126442B (https=) |
| IL (1) | IL232356B (https=) |
| IN (1) | IN2014MN00968A (https=) |
| MX (1) | MX356454B (https=) |
| PL (1) | PL2773753T3 (https=) |
| RU (1) | RU2668396C2 (https=) |
| WO (1) | WO2013064736A1 (https=) |
| ZA (1) | ZA201403965B (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105462950A (zh) * | 2016-02-16 | 2016-04-06 | 上海青瑞食品科技有限公司 | 一种液体酶制剂及制备方法 |
| CN105852053A (zh) * | 2016-04-20 | 2016-08-17 | 上海青瑞食品科技有限公司 | 一种液体酶制剂在食品质构改良中的应用 |
| CN107897533A (zh) * | 2017-12-10 | 2018-04-13 | 济南诺能生物工程有限公司 | 一种单胃动物液体复合酶的制备方法 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014061728A1 (ja) * | 2012-10-17 | 2014-04-24 | 味の素株式会社 | 化粧料組成物 |
| RU2018138463A (ru) | 2016-04-01 | 2020-05-12 | Оатли Аб | Овсяная основа с повышенной вязкостью и ферментированный продукт из овсяной основы |
| JP6787563B2 (ja) * | 2016-06-30 | 2020-11-18 | 千葉製粉株式会社 | 接着成形食品の製造方法、接着成形食品用の接着成分分散液、および、接着成形食品 |
| WO2019182123A1 (ja) | 2018-03-23 | 2019-09-26 | 味の素株式会社 | トランスグルタミナーゼを含有する液体製剤 |
| US20230114377A1 (en) * | 2020-03-17 | 2023-04-13 | Amano Enzyme Inc. | Protein crosslinking method |
| MX2022014108A (es) * | 2020-05-13 | 2023-02-23 | Curie Co Inc | Variantes de transglutaminasa y aplicaciones de uso de las mismas. |
| EP4212024A4 (en) * | 2020-09-10 | 2024-10-02 | Amano Enzyme Inc. | TOFU PRODUCTION PROCESS |
| CN116057184A (zh) * | 2020-09-10 | 2023-05-02 | 天野酶制品株式会社 | 加工蛋白质的制造方法 |
| JP7829496B2 (ja) * | 2020-12-04 | 2026-03-13 | 天野エンザイム株式会社 | 液体酵素製剤 |
| WO2023058616A1 (ja) | 2021-10-04 | 2023-04-13 | 天野エンザイム株式会社 | 液状トランスグルタミナーゼ酵素製剤 |
| WO2023228953A1 (ja) | 2022-05-23 | 2023-11-30 | 天野エンザイム株式会社 | 液体酵素製剤 |
| CN115380981A (zh) * | 2022-08-09 | 2022-11-25 | 武汉新华扬生物股份有限公司 | 一种用于冷萃咖啡的复配酶制剂及其应用方法 |
| EP4428218A1 (en) * | 2023-03-07 | 2024-09-11 | SkyLab AG | Biodegradable transglutaminase-based detergent composition for regeneration of microdamage and regulation of elasticity of delicate fiber |
| AU2024303157A1 (en) | 2023-06-14 | 2026-01-08 | Amano Enzyme Inc. | Liquid enzyme preparation |
| CN121620590A (zh) | 2023-09-01 | 2026-03-06 | 诺维信公司 | 稳定的液体脱酰胺酶组合物 |
| WO2025056701A1 (en) * | 2023-09-13 | 2025-03-20 | Novozymes A/S | Stabilized deamidase compositions |
| WO2025233391A1 (en) * | 2024-05-09 | 2025-11-13 | Novozymes A/S | Stabilized liquid deamidase compositions |
| EP4650443A1 (en) * | 2024-05-13 | 2025-11-19 | Novozymes A/S | Stabilized liquid deamidase compositions |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5340734A (en) * | 1992-11-25 | 1994-08-23 | Biosource Genetics Corporation | Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom |
| CN1684593A (zh) * | 2002-09-26 | 2005-10-19 | 味之素株式会社 | 酶制剂及用其生产食品的方法 |
| EP2251421A1 (en) * | 2008-02-13 | 2010-11-17 | Amano Enzyme Inc. | Stabilized transglutaminase and process for production thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0665280B2 (ja) | 1987-03-04 | 1994-08-24 | 味の素株式会社 | タンパクゲル化剤及びそれを用いるタンパクのゲル化方法 |
| PL177022B1 (pl) * | 1994-04-18 | 1999-09-30 | Gist Brocades Bv | Trwała emulsja typu woda w oleju |
| DE69535037T2 (de) | 1994-08-26 | 2006-12-07 | Novozymes A/S | Mikrobielle transglutaminasen, ihre herstellung und ihre verwendung |
| EP0973875B1 (en) * | 1997-03-12 | 2006-06-14 | Novozymes A/S | Storage-stable liquid formulation comprising a laccase |
| CA2421833A1 (en) * | 2000-09-28 | 2002-04-04 | Dsm N.V. | Liquid bread improving compositions |
| US20030219853A1 (en) * | 2002-03-01 | 2003-11-27 | Szu-Yi Chou | Method of cross-linking a compound |
| JP2005034078A (ja) * | 2003-07-17 | 2005-02-10 | Rengo Co Ltd | タンパク質安定化剤 |
| EP1836897A1 (en) * | 2006-03-22 | 2007-09-26 | Nestec S.A. | A solid product comprising oil-droplets |
| GB2438287A (en) * | 2006-05-19 | 2007-11-21 | Norbrook Lab Ltd | Stable aqueous suspension |
| US20110064847A1 (en) * | 2008-03-14 | 2011-03-17 | Ajinomoto Co., Inc. | Method of denaturing protein with enzymes |
| WO2009152176A2 (en) * | 2008-06-09 | 2009-12-17 | Danisco Us Inc., Genencor Division | Recovery of insoluble enzyme from fermentation broth and formulation of insoluble enzyme |
-
2011
- 2011-11-01 FI FI20116074A patent/FI126442B/en active IP Right Grant
-
2012
- 2012-10-31 DK DK12788227.2T patent/DK2773753T3/en active
- 2012-10-31 KR KR1020147014440A patent/KR101998182B1/ko active Active
- 2012-10-31 CN CN201280053784.3A patent/CN104024406A/zh active Pending
- 2012-10-31 BR BR112014010222-8A patent/BR112014010222B1/pt not_active IP Right Cessation
- 2012-10-31 ES ES12788227T patent/ES2697675T3/es active Active
- 2012-10-31 US US14/353,718 patent/US20140287098A1/en not_active Abandoned
- 2012-10-31 EP EP12788227.2A patent/EP2773753B1/en active Active
- 2012-10-31 MX MX2014005128A patent/MX356454B/es active IP Right Grant
- 2012-10-31 IN IN968MUN2014 patent/IN2014MN00968A/en unknown
- 2012-10-31 CN CN201810281980.5A patent/CN108676782A/zh active Pending
- 2012-10-31 AU AU2012331034A patent/AU2012331034B2/en active Active
- 2012-10-31 RU RU2014121318A patent/RU2668396C2/ru active
- 2012-10-31 CA CA2853711A patent/CA2853711C/en active Active
- 2012-10-31 JP JP2014539370A patent/JP6297979B2/ja active Active
- 2012-10-31 WO PCT/FI2012/051048 patent/WO2013064736A1/en not_active Ceased
- 2012-10-31 PL PL12788227T patent/PL2773753T3/pl unknown
-
2014
- 2014-04-29 IL IL232356A patent/IL232356B/en active IP Right Grant
- 2014-04-29 CL CL2014001100A patent/CL2014001100A1/es unknown
- 2014-05-29 ZA ZA2014/03965A patent/ZA201403965B/en unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5340734A (en) * | 1992-11-25 | 1994-08-23 | Biosource Genetics Corporation | Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom |
| CN1684593A (zh) * | 2002-09-26 | 2005-10-19 | 味之素株式会社 | 酶制剂及用其生产食品的方法 |
| EP2251421A1 (en) * | 2008-02-13 | 2010-11-17 | Amano Enzyme Inc. | Stabilized transglutaminase and process for production thereof |
Non-Patent Citations (2)
| Title |
|---|
| SHELBY L., ET AL.: "Glycerol as an Enzyme-Stabilizing Agent: Effects on Aldehyde Dehydrogenase", 《PNAS》, vol. 69, no. 9, 30 September 1972 (1972-09-30), pages 2373 - 2376, XP055049969, DOI: doi:10.1073/pnas.69.9.2373 * |
| YU-JEN YU, ET AL.: "Overproduction of soluble recombinant transglutaminase from Streptomyces netropsis in Escherichia coli", 《APPL MICROBIOL BIOTECHNOL》, vol. 81, 20 September 2008 (2008-09-20), pages 523 - 532, XP019654175, DOI: doi:10.1007/s00253-008-1688-7 * |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107245481A (zh) * | 2016-02-16 | 2017-10-13 | 上海青瑞食品科技有限公司 | 一种液体酶制剂及制备方法 |
| WO2017140051A1 (zh) | 2016-02-16 | 2017-08-24 | 上海青瑞食品科技有限公司 | 一种液体酶制剂及制备方法 |
| CN107177582A (zh) * | 2016-02-16 | 2017-09-19 | 上海青瑞食品科技有限公司 | 一种液体酶制剂及制备方法 |
| CN107177567A (zh) * | 2016-02-16 | 2017-09-19 | 上海青瑞食品科技有限公司 | 一种液体酶制剂及制备方法 |
| CN105462950B (zh) * | 2016-02-16 | 2017-09-26 | 上海青瑞食品科技有限公司 | 一种液体酶制剂及制备方法 |
| CN105462950A (zh) * | 2016-02-16 | 2016-04-06 | 上海青瑞食品科技有限公司 | 一种液体酶制剂及制备方法 |
| CN107326019A (zh) * | 2016-02-16 | 2017-11-07 | 上海青瑞食品科技有限公司 | 一种液体酶制剂及制备方法 |
| CN107326019B (zh) * | 2016-02-16 | 2018-05-01 | 上海青瑞食品科技有限公司 | 一种液体酶制剂及制备方法 |
| CN107177582B (zh) * | 2016-02-16 | 2018-05-22 | 上海青瑞食品科技有限公司 | 一种液体酶制剂及制备方法 |
| CN107245481B (zh) * | 2016-02-16 | 2018-06-01 | 上海青瑞食品科技有限公司 | 一种液体酶制剂及制备方法 |
| CN107177567B (zh) * | 2016-02-16 | 2018-07-03 | 上海青瑞食品科技有限公司 | 一种液体酶制剂及制备方法 |
| CN105852053A (zh) * | 2016-04-20 | 2016-08-17 | 上海青瑞食品科技有限公司 | 一种液体酶制剂在食品质构改良中的应用 |
| CN107897533A (zh) * | 2017-12-10 | 2018-04-13 | 济南诺能生物工程有限公司 | 一种单胃动物液体复合酶的制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2697675T3 (es) | 2019-01-25 |
| JP2014532421A (ja) | 2014-12-08 |
| WO2013064736A1 (en) | 2013-05-10 |
| IL232356A0 (en) | 2014-06-30 |
| ZA201403965B (en) | 2015-05-27 |
| BR112014010222A2 (pt) | 2017-06-13 |
| EP2773753A1 (en) | 2014-09-10 |
| IL232356B (en) | 2019-03-31 |
| BR112014010222A8 (pt) | 2017-06-20 |
| JP6297979B2 (ja) | 2018-03-20 |
| FI20116074L (fi) | 2013-05-02 |
| RU2014121318A (ru) | 2015-12-10 |
| US20140287098A1 (en) | 2014-09-25 |
| MX2014005128A (es) | 2014-07-09 |
| RU2668396C2 (ru) | 2018-09-28 |
| PL2773753T3 (pl) | 2019-03-29 |
| AU2012331034A1 (en) | 2014-06-26 |
| AU2012331034B2 (en) | 2017-10-19 |
| IN2014MN00968A (https=) | 2015-04-24 |
| CA2853711C (en) | 2019-11-26 |
| BR112014010222B1 (pt) | 2022-04-12 |
| CL2014001100A1 (es) | 2014-09-05 |
| DK2773753T3 (en) | 2018-12-10 |
| MX356454B (es) | 2018-05-30 |
| CA2853711A1 (en) | 2013-05-10 |
| EP2773753B1 (en) | 2018-10-17 |
| KR101998182B1 (ko) | 2019-10-01 |
| KR20140096090A (ko) | 2014-08-04 |
| CN108676782A (zh) | 2018-10-19 |
| FI126442B (en) | 2016-12-15 |
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Application publication date: 20140903 |