BR112014010222B1 - Formulação de enzima líquida e processo para sua preparação - Google Patents

Formulação de enzima líquida e processo para sua preparação Download PDF

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Publication number
BR112014010222B1
BR112014010222B1 BR112014010222-8A BR112014010222A BR112014010222B1 BR 112014010222 B1 BR112014010222 B1 BR 112014010222B1 BR 112014010222 A BR112014010222 A BR 112014010222A BR 112014010222 B1 BR112014010222 B1 BR 112014010222B1
Authority
BR
Brazil
Prior art keywords
transglutaminase
enzyme
formulation
preparation
suspension
Prior art date
Application number
BR112014010222-8A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112014010222A2 (pt
BR112014010222A8 (pt
Inventor
Kirsi Rajakari
Kai Hotakainen
Päivi Myllärinen
Original Assignee
Valio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valio Ltd filed Critical Valio Ltd
Publication of BR112014010222A2 publication Critical patent/BR112014010222A2/pt
Publication of BR112014010222A8 publication Critical patent/BR112014010222A8/pt
Publication of BR112014010222B1 publication Critical patent/BR112014010222B1/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/104Aminoacyltransferases (2.3.2)
    • C12N9/1044Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06Enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0055Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
    • C12N9/0057Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
    • C12N9/0059Catechol oxidase (1.10.3.1), i.e. tyrosinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0055Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
    • C12N9/0057Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
    • C12N9/0061Laccase (1.10.3.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y110/00Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03001Catechol oxidase (1.10.3.1), i.e. tyrosinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y110/00Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03002Laccase (1.10.3.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/02Aminoacyltransferases (2.3.2)
    • C12Y203/02013Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y305/00Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01043Peptidyl-glutaminase (3.5.1.43)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
BR112014010222-8A 2011-11-01 2012-10-31 Formulação de enzima líquida e processo para sua preparação BR112014010222B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20116074A FI126442B (en) 2011-11-01 2011-11-01 Liquid enzyme preparation and process for its preparation
PCT/FI2012/051048 WO2013064736A1 (en) 2011-11-01 2012-10-31 A liquid enzyme formulation and a process for its preparation

Publications (3)

Publication Number Publication Date
BR112014010222A2 BR112014010222A2 (pt) 2017-06-13
BR112014010222A8 BR112014010222A8 (pt) 2017-06-20
BR112014010222B1 true BR112014010222B1 (pt) 2022-04-12

Family

ID=47215584

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014010222-8A BR112014010222B1 (pt) 2011-11-01 2012-10-31 Formulação de enzima líquida e processo para sua preparação

Country Status (19)

Country Link
US (1) US20140287098A1 (https=)
EP (1) EP2773753B1 (https=)
JP (1) JP6297979B2 (https=)
KR (1) KR101998182B1 (https=)
CN (2) CN104024406A (https=)
AU (1) AU2012331034B2 (https=)
BR (1) BR112014010222B1 (https=)
CA (1) CA2853711C (https=)
CL (1) CL2014001100A1 (https=)
DK (1) DK2773753T3 (https=)
ES (1) ES2697675T3 (https=)
FI (1) FI126442B (https=)
IL (1) IL232356B (https=)
IN (1) IN2014MN00968A (https=)
MX (1) MX356454B (https=)
PL (1) PL2773753T3 (https=)
RU (1) RU2668396C2 (https=)
WO (1) WO2013064736A1 (https=)
ZA (1) ZA201403965B (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014061728A1 (ja) * 2012-10-17 2014-04-24 味の素株式会社 化粧料組成物
CN107326019B (zh) * 2016-02-16 2018-05-01 上海青瑞食品科技有限公司 一种液体酶制剂及制备方法
RU2018138463A (ru) 2016-04-01 2020-05-12 Оатли Аб Овсяная основа с повышенной вязкостью и ферментированный продукт из овсяной основы
CN105852053A (zh) * 2016-04-20 2016-08-17 上海青瑞食品科技有限公司 一种液体酶制剂在食品质构改良中的应用
JP6787563B2 (ja) * 2016-06-30 2020-11-18 千葉製粉株式会社 接着成形食品の製造方法、接着成形食品用の接着成分分散液、および、接着成形食品
CN107897533A (zh) * 2017-12-10 2018-04-13 济南诺能生物工程有限公司 一种单胃动物液体复合酶的制备方法
WO2019182123A1 (ja) 2018-03-23 2019-09-26 味の素株式会社 トランスグルタミナーゼを含有する液体製剤
US20230114377A1 (en) * 2020-03-17 2023-04-13 Amano Enzyme Inc. Protein crosslinking method
MX2022014108A (es) * 2020-05-13 2023-02-23 Curie Co Inc Variantes de transglutaminasa y aplicaciones de uso de las mismas.
EP4212024A4 (en) * 2020-09-10 2024-10-02 Amano Enzyme Inc. TOFU PRODUCTION PROCESS
CN116057184A (zh) * 2020-09-10 2023-05-02 天野酶制品株式会社 加工蛋白质的制造方法
JP7829496B2 (ja) * 2020-12-04 2026-03-13 天野エンザイム株式会社 液体酵素製剤
WO2023058616A1 (ja) 2021-10-04 2023-04-13 天野エンザイム株式会社 液状トランスグルタミナーゼ酵素製剤
WO2023228953A1 (ja) 2022-05-23 2023-11-30 天野エンザイム株式会社 液体酵素製剤
CN115380981A (zh) * 2022-08-09 2022-11-25 武汉新华扬生物股份有限公司 一种用于冷萃咖啡的复配酶制剂及其应用方法
EP4428218A1 (en) * 2023-03-07 2024-09-11 SkyLab AG Biodegradable transglutaminase-based detergent composition for regeneration of microdamage and regulation of elasticity of delicate fiber
AU2024303157A1 (en) 2023-06-14 2026-01-08 Amano Enzyme Inc. Liquid enzyme preparation
CN121620590A (zh) 2023-09-01 2026-03-06 诺维信公司 稳定的液体脱酰胺酶组合物
WO2025056701A1 (en) * 2023-09-13 2025-03-20 Novozymes A/S Stabilized deamidase compositions
WO2025233391A1 (en) * 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions
EP4650443A1 (en) * 2024-05-13 2025-11-19 Novozymes A/S Stabilized liquid deamidase compositions

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665280B2 (ja) 1987-03-04 1994-08-24 味の素株式会社 タンパクゲル化剤及びそれを用いるタンパクのゲル化方法
US5340734A (en) * 1992-11-25 1994-08-23 Biosource Genetics Corporation Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
PL177022B1 (pl) * 1994-04-18 1999-09-30 Gist Brocades Bv Trwała emulsja typu woda w oleju
DE69535037T2 (de) 1994-08-26 2006-12-07 Novozymes A/S Mikrobielle transglutaminasen, ihre herstellung und ihre verwendung
EP0973875B1 (en) * 1997-03-12 2006-06-14 Novozymes A/S Storage-stable liquid formulation comprising a laccase
CA2421833A1 (en) * 2000-09-28 2002-04-04 Dsm N.V. Liquid bread improving compositions
US20030219853A1 (en) * 2002-03-01 2003-11-27 Szu-Yi Chou Method of cross-linking a compound
EP1543732B1 (en) * 2002-09-26 2013-10-23 Ajinomoto Co., Inc. Enzyme preparation and process for producing food using the same
JP2005034078A (ja) * 2003-07-17 2005-02-10 Rengo Co Ltd タンパク質安定化剤
EP1836897A1 (en) * 2006-03-22 2007-09-26 Nestec S.A. A solid product comprising oil-droplets
GB2438287A (en) * 2006-05-19 2007-11-21 Norbrook Lab Ltd Stable aqueous suspension
DK2251421T3 (en) * 2008-02-13 2017-02-06 Amano Enzyme Inc Stabilized transglutaminase and process for its preparation
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WO2009152176A2 (en) * 2008-06-09 2009-12-17 Danisco Us Inc., Genencor Division Recovery of insoluble enzyme from fermentation broth and formulation of insoluble enzyme

Also Published As

Publication number Publication date
ES2697675T3 (es) 2019-01-25
JP2014532421A (ja) 2014-12-08
WO2013064736A1 (en) 2013-05-10
IL232356A0 (en) 2014-06-30
ZA201403965B (en) 2015-05-27
BR112014010222A2 (pt) 2017-06-13
EP2773753A1 (en) 2014-09-10
IL232356B (en) 2019-03-31
BR112014010222A8 (pt) 2017-06-20
JP6297979B2 (ja) 2018-03-20
FI20116074L (fi) 2013-05-02
CN104024406A (zh) 2014-09-03
RU2014121318A (ru) 2015-12-10
US20140287098A1 (en) 2014-09-25
MX2014005128A (es) 2014-07-09
RU2668396C2 (ru) 2018-09-28
PL2773753T3 (pl) 2019-03-29
AU2012331034A1 (en) 2014-06-26
AU2012331034B2 (en) 2017-10-19
IN2014MN00968A (https=) 2015-04-24
CA2853711C (en) 2019-11-26
CL2014001100A1 (es) 2014-09-05
DK2773753T3 (en) 2018-12-10
MX356454B (es) 2018-05-30
CA2853711A1 (en) 2013-05-10
EP2773753B1 (en) 2018-10-17
KR101998182B1 (ko) 2019-10-01
KR20140096090A (ko) 2014-08-04
CN108676782A (zh) 2018-10-19
FI126442B (en) 2016-12-15

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B15I Others concerning applications: loss of priority

Free format text: PERDA DA PRIORIDADE FI 20116074, DE 01/11/2011 REIVINDICADA NO PCT/FI2012/051048, CONFORME AS DISPOSICOES PREVISTAS NA LEI 9.279 DE 14/05/1996 (LPI) ART. 16 7O, ITEM 28 DO ATO NORMATIVO 128/97 E NO ART. 29 DA RESOLUCAO INPI-PR 77/2013. ESTA PERDA SE DEU PELO FATO DE O DEPOSITANTE CONSTANTE DA PETICAO DE REQUERIMENTO DO PEDIDO PCT (?VALIO LTD?) SER DISTINTO DAQUELE QUE DEPOSITOU A PRIORIDADE REIVINDICADA E NAO FOI APRESENTADO O DOCUMENTO COMPROBATORIO DE CESSAO NO PRAZO LEGAL, CONFORME AS DISPOSICOES PREVISTAS NA LEI 9.279 DE 14/05/1996 (LPI) ART. 16 6O, ITEM 27 DO ATO NORMATIVO 128/97 E NO ART. 2 DA RESOLUCAO INPIPR 179/2017.

B12F Other appeals [chapter 12.6 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 31/10/2012, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 13A ANUIDADE.

B24D Patent annual fee: restoration after fee payment