CA2853711C - A liquid enzyme formulation and a process for its preparation - Google Patents

A liquid enzyme formulation and a process for its preparation Download PDF

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Publication number
CA2853711C
CA2853711C CA2853711A CA2853711A CA2853711C CA 2853711 C CA2853711 C CA 2853711C CA 2853711 A CA2853711 A CA 2853711A CA 2853711 A CA2853711 A CA 2853711A CA 2853711 C CA2853711 C CA 2853711C
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Prior art keywords
transglutaminase
formulation
polyol
enzyme
suspension
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CA2853711A
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English (en)
French (fr)
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CA2853711A1 (en
Inventor
Kirsi Rajakari
Kai Hotakainen
Paivi Myllarinen
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Valio Oy
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/104Aminoacyltransferases (2.3.2)
    • C12N9/1044Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06Enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0055Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
    • C12N9/0057Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
    • C12N9/0059Catechol oxidase (1.10.3.1), i.e. tyrosinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0055Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
    • C12N9/0057Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
    • C12N9/0061Laccase (1.10.3.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y110/00Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03001Catechol oxidase (1.10.3.1), i.e. tyrosinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y110/00Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03002Laccase (1.10.3.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/02Aminoacyltransferases (2.3.2)
    • C12Y203/02013Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y305/00Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01043Peptidyl-glutaminase (3.5.1.43)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
CA2853711A 2011-11-01 2012-10-31 A liquid enzyme formulation and a process for its preparation Active CA2853711C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI20116074 2011-11-01
FI20116074A FI126442B (en) 2011-11-01 2011-11-01 Liquid enzyme preparation and process for its preparation
PCT/FI2012/051048 WO2013064736A1 (en) 2011-11-01 2012-10-31 A liquid enzyme formulation and a process for its preparation

Publications (2)

Publication Number Publication Date
CA2853711A1 CA2853711A1 (en) 2013-05-10
CA2853711C true CA2853711C (en) 2019-11-26

Family

ID=47215584

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2853711A Active CA2853711C (en) 2011-11-01 2012-10-31 A liquid enzyme formulation and a process for its preparation

Country Status (19)

Country Link
US (1) US20140287098A1 (https=)
EP (1) EP2773753B1 (https=)
JP (1) JP6297979B2 (https=)
KR (1) KR101998182B1 (https=)
CN (2) CN104024406A (https=)
AU (1) AU2012331034B2 (https=)
BR (1) BR112014010222B1 (https=)
CA (1) CA2853711C (https=)
CL (1) CL2014001100A1 (https=)
DK (1) DK2773753T3 (https=)
ES (1) ES2697675T3 (https=)
FI (1) FI126442B (https=)
IL (1) IL232356B (https=)
IN (1) IN2014MN00968A (https=)
MX (1) MX356454B (https=)
PL (1) PL2773753T3 (https=)
RU (1) RU2668396C2 (https=)
WO (1) WO2013064736A1 (https=)
ZA (1) ZA201403965B (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014061728A1 (ja) * 2012-10-17 2014-04-24 味の素株式会社 化粧料組成物
CN107326019B (zh) * 2016-02-16 2018-05-01 上海青瑞食品科技有限公司 一种液体酶制剂及制备方法
RU2018138463A (ru) 2016-04-01 2020-05-12 Оатли Аб Овсяная основа с повышенной вязкостью и ферментированный продукт из овсяной основы
CN105852053A (zh) * 2016-04-20 2016-08-17 上海青瑞食品科技有限公司 一种液体酶制剂在食品质构改良中的应用
JP6787563B2 (ja) * 2016-06-30 2020-11-18 千葉製粉株式会社 接着成形食品の製造方法、接着成形食品用の接着成分分散液、および、接着成形食品
CN107897533A (zh) * 2017-12-10 2018-04-13 济南诺能生物工程有限公司 一种单胃动物液体复合酶的制备方法
WO2019182123A1 (ja) 2018-03-23 2019-09-26 味の素株式会社 トランスグルタミナーゼを含有する液体製剤
US20230114377A1 (en) * 2020-03-17 2023-04-13 Amano Enzyme Inc. Protein crosslinking method
MX2022014108A (es) * 2020-05-13 2023-02-23 Curie Co Inc Variantes de transglutaminasa y aplicaciones de uso de las mismas.
EP4212024A4 (en) * 2020-09-10 2024-10-02 Amano Enzyme Inc. TOFU PRODUCTION PROCESS
CN116057184A (zh) * 2020-09-10 2023-05-02 天野酶制品株式会社 加工蛋白质的制造方法
JP7829496B2 (ja) * 2020-12-04 2026-03-13 天野エンザイム株式会社 液体酵素製剤
WO2023058616A1 (ja) 2021-10-04 2023-04-13 天野エンザイム株式会社 液状トランスグルタミナーゼ酵素製剤
WO2023228953A1 (ja) 2022-05-23 2023-11-30 天野エンザイム株式会社 液体酵素製剤
CN115380981A (zh) * 2022-08-09 2022-11-25 武汉新华扬生物股份有限公司 一种用于冷萃咖啡的复配酶制剂及其应用方法
EP4428218A1 (en) * 2023-03-07 2024-09-11 SkyLab AG Biodegradable transglutaminase-based detergent composition for regeneration of microdamage and regulation of elasticity of delicate fiber
AU2024303157A1 (en) 2023-06-14 2026-01-08 Amano Enzyme Inc. Liquid enzyme preparation
CN121620590A (zh) 2023-09-01 2026-03-06 诺维信公司 稳定的液体脱酰胺酶组合物
WO2025056701A1 (en) * 2023-09-13 2025-03-20 Novozymes A/S Stabilized deamidase compositions
WO2025233391A1 (en) * 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions
EP4650443A1 (en) * 2024-05-13 2025-11-19 Novozymes A/S Stabilized liquid deamidase compositions

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665280B2 (ja) 1987-03-04 1994-08-24 味の素株式会社 タンパクゲル化剤及びそれを用いるタンパクのゲル化方法
US5340734A (en) * 1992-11-25 1994-08-23 Biosource Genetics Corporation Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
PL177022B1 (pl) * 1994-04-18 1999-09-30 Gist Brocades Bv Trwała emulsja typu woda w oleju
DE69535037T2 (de) 1994-08-26 2006-12-07 Novozymes A/S Mikrobielle transglutaminasen, ihre herstellung und ihre verwendung
EP0973875B1 (en) * 1997-03-12 2006-06-14 Novozymes A/S Storage-stable liquid formulation comprising a laccase
CA2421833A1 (en) * 2000-09-28 2002-04-04 Dsm N.V. Liquid bread improving compositions
US20030219853A1 (en) * 2002-03-01 2003-11-27 Szu-Yi Chou Method of cross-linking a compound
EP1543732B1 (en) * 2002-09-26 2013-10-23 Ajinomoto Co., Inc. Enzyme preparation and process for producing food using the same
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WO2009152176A2 (en) * 2008-06-09 2009-12-17 Danisco Us Inc., Genencor Division Recovery of insoluble enzyme from fermentation broth and formulation of insoluble enzyme

Also Published As

Publication number Publication date
ES2697675T3 (es) 2019-01-25
JP2014532421A (ja) 2014-12-08
WO2013064736A1 (en) 2013-05-10
IL232356A0 (en) 2014-06-30
ZA201403965B (en) 2015-05-27
BR112014010222A2 (pt) 2017-06-13
EP2773753A1 (en) 2014-09-10
IL232356B (en) 2019-03-31
BR112014010222A8 (pt) 2017-06-20
JP6297979B2 (ja) 2018-03-20
FI20116074L (fi) 2013-05-02
CN104024406A (zh) 2014-09-03
RU2014121318A (ru) 2015-12-10
US20140287098A1 (en) 2014-09-25
MX2014005128A (es) 2014-07-09
RU2668396C2 (ru) 2018-09-28
PL2773753T3 (pl) 2019-03-29
AU2012331034A1 (en) 2014-06-26
AU2012331034B2 (en) 2017-10-19
IN2014MN00968A (https=) 2015-04-24
BR112014010222B1 (pt) 2022-04-12
CL2014001100A1 (es) 2014-09-05
DK2773753T3 (en) 2018-12-10
MX356454B (es) 2018-05-30
CA2853711A1 (en) 2013-05-10
EP2773753B1 (en) 2018-10-17
KR101998182B1 (ko) 2019-10-01
KR20140096090A (ko) 2014-08-04
CN108676782A (zh) 2018-10-19
FI126442B (en) 2016-12-15

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