CN104024255B - 作为btk活性的抑制剂的烷基化哌嗪化合物 - Google Patents

作为btk活性的抑制剂的烷基化哌嗪化合物 Download PDF

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CN104024255B
CN104024255B CN201280065838.8A CN201280065838A CN104024255B CN 104024255 B CN104024255 B CN 104024255B CN 201280065838 A CN201280065838 A CN 201280065838A CN 104024255 B CN104024255 B CN 104024255B
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methyl
cancer
pyridin
oxo
mmol
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CN104024255A (zh
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J.J.克劳福德
W.B.扬
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F Hoffmann La Roche AG
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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CN201280065838.8A 2011-11-03 2012-11-02 作为btk活性的抑制剂的烷基化哌嗪化合物 Expired - Fee Related CN104024255B (zh)

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Application Number Priority Date Filing Date Title
US201161555395P 2011-11-03 2011-11-03
US61/555,395 2011-11-03
PCT/US2012/063198 WO2013067277A1 (en) 2011-11-03 2012-11-02 Alkylated piperazine compounds as inhibitors of btk activity

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CN104024255A CN104024255A (zh) 2014-09-03
CN104024255B true CN104024255B (zh) 2017-01-18

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