CN104010659A - 非唾液酸化的抗炎多肽 - Google Patents

非唾液酸化的抗炎多肽 Download PDF

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Publication number
CN104010659A
CN104010659A CN201280062837.8A CN201280062837A CN104010659A CN 104010659 A CN104010659 A CN 104010659A CN 201280062837 A CN201280062837 A CN 201280062837A CN 104010659 A CN104010659 A CN 104010659A
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Prior art keywords
polypeptide
nucleic acid
sequence
isolated polypeptide
igg
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CN201280062837.8A
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Chinese (zh)
Inventor
杰夫瑞·V·华弗治
安德鲁·品洛狄克
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Rockefeller University
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Rockefeller University
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Priority to CN202311583469.8A priority Critical patent/CN117964709A/zh
Publication of CN104010659A publication Critical patent/CN104010659A/zh
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
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CN201280062837.8A 2011-12-19 2012-12-10 非唾液酸化的抗炎多肽 Pending CN104010659A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311583469.8A CN117964709A (zh) 2011-12-19 2012-12-10 非唾液酸化的抗炎多肽

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161577361P 2011-12-19 2011-12-19
US61/577,361 2011-12-19
PCT/US2012/068718 WO2013095966A1 (en) 2011-12-19 2012-12-10 Non-sialylated anti-inflammatory polypeptides

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CN202311583469.8A Division CN117964709A (zh) 2011-12-19 2012-12-10 非唾液酸化的抗炎多肽

Publications (1)

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CN104010659A true CN104010659A (zh) 2014-08-27

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CN201280062837.8A Pending CN104010659A (zh) 2011-12-19 2012-12-10 非唾液酸化的抗炎多肽
CN202311583469.8A Pending CN117964709A (zh) 2011-12-19 2012-12-10 非唾液酸化的抗炎多肽

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US (5) US9587025B2 (enExample)
EP (2) EP3485909A1 (enExample)
JP (6) JP6322872B2 (enExample)
CN (2) CN104010659A (enExample)
AU (1) AU2012355710B2 (enExample)
CA (1) CA2859022A1 (enExample)
EA (2) EA031715B1 (enExample)
ES (1) ES2692539T3 (enExample)
IL (2) IL233082B (enExample)
IN (1) IN2014CN04765A (enExample)
MX (1) MX357923B (enExample)
PT (1) PT2793943T (enExample)
SG (3) SG10201805962PA (enExample)
WO (1) WO2013095966A1 (enExample)
ZA (1) ZA201405185B (enExample)

Cited By (2)

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CN107847586A (zh) * 2015-03-04 2018-03-27 洛克菲勒大学 抗炎多肽
CN108026163A (zh) * 2015-07-06 2018-05-11 法国血液分割暨生化制品实验室 修饰的Fc片段在免疫疗法中的应用

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US12384848B2 (en) 2011-12-19 2025-08-12 The Rockefeller University Anti-inflammatory polypeptides
CN104010659A (zh) 2011-12-19 2014-08-27 洛克菲勒大学 非唾液酸化的抗炎多肽
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
WO2013158279A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Protein purification methods to reduce acidic species
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
CA2905010A1 (en) 2013-03-12 2014-09-18 Abbvie Inc. Human antibodies that bind human tnf-alpha and methods of preparing the same
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US20160215061A1 (en) * 2013-10-08 2016-07-28 Merck Sharp & Dohme Corp. Fc CONTAINING POLYPEPTIDES HAVING INCREASED BINDING TO FcGammaRIIB
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
DK3221363T3 (da) 2014-11-21 2020-08-10 Bristol Myers Squibb Co Antistoffer mod cd73 og anvendelser deraf
HRP20201756T8 (hr) 2014-11-21 2021-08-20 Bristol-Myers Squibb Company Antitijela koja sadrže modificirane regije teškog lanca
SG10202006538TA (en) 2014-12-23 2020-08-28 Bristol Myers Squibb Co Antibodies to tigit
US10300127B2 (en) 2015-03-20 2019-05-28 The Rockefeller University Immune complex
LT3303396T (lt) 2015-05-29 2023-01-10 Bristol-Myers Squibb Company Antikūnai prieš ox40 ir jų panaudojimo būdai
MX2017016502A (es) 2015-06-29 2018-03-12 Univ Rockefeller Anticuerpos contra cd40 con actividad agonista mejorada.
CA3016534A1 (en) 2016-03-04 2017-09-08 The Rockefeller University Antibodies to cd40 with enhanced agonist activity
KR20180118725A (ko) 2016-03-04 2018-10-31 브리스톨-마이어스 스큅 컴퍼니 항-cd73 항체와의 조합 요법
EP3551749B1 (en) 2016-12-07 2023-09-27 East Carolina University Compositions and methods for in vitro cultivation and/or expansion of regulatory t cells
TWI788340B (zh) 2017-04-07 2023-01-01 美商必治妥美雅史谷比公司 抗icos促效劑抗體及其用途
IL270596B1 (en) 2017-05-25 2025-09-01 Bristol Myers Squibb Co Antibodies comprising modified heavy constant region for use in treating cancer
CN111032688A (zh) * 2017-08-11 2020-04-17 研究发展基金会 用于延长的血清半衰期的工程化抗体fc变体
CA3085472A1 (en) 2017-12-19 2019-06-27 The Rockefeller University Human igg fc domain variants with improved effector function
KR102813744B1 (ko) 2017-12-27 2025-05-28 브리스톨-마이어스 스큅 컴퍼니 항-cd40 항체 및 그의 용도
WO2020089811A1 (en) 2018-10-31 2020-05-07 Novartis Ag Dc-sign antibody drug conjugates
TW202033555A (zh) 2018-11-16 2020-09-16 美商必治妥美雅史谷比公司 抗nkg2a抗體及其用途
KR20210096167A (ko) 2018-11-28 2021-08-04 브리스톨-마이어스 스큅 컴퍼니 변형된 중쇄 불변 영역을 포함하는 항체
US20230192867A1 (en) 2020-05-15 2023-06-22 Bristol-Myers Squibb Company Antibodies to garp

Citations (3)

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