CN103998052B - 用于治疗疾病和紊乱的肽类似物 - Google Patents

用于治疗疾病和紊乱的肽类似物 Download PDF

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Publication number
CN103998052B
CN103998052B CN201280062729.0A CN201280062729A CN103998052B CN 103998052 B CN103998052 B CN 103998052B CN 201280062729 A CN201280062729 A CN 201280062729A CN 103998052 B CN103998052 B CN 103998052B
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CN
China
Prior art keywords
oral
seq
peptide
sct
glucose
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Expired - Fee Related
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CN201280062729.0A
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English (en)
Chinese (zh)
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CN103998052A (zh
Inventor
诺泽·M·梅赫塔
威廉·斯特恩
艾米·M·施蒂默尔
莫滕·阿塞尔·卡尔斯达尔
基姆·亨里克森
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Guanjian Biological Science Co Ltd
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Guanjian Biological Science Co Ltd
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Publication of CN103998052A publication Critical patent/CN103998052A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
CN201280062729.0A 2011-11-02 2012-11-02 用于治疗疾病和紊乱的肽类似物 Expired - Fee Related CN103998052B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161554771P 2011-11-02 2011-11-02
US61/554,771 2011-11-02
US201161578620P 2011-12-21 2011-12-21
US61/578,620 2011-12-21
PCT/US2012/063332 WO2013067357A1 (en) 2011-11-02 2012-11-02 Peptide analogs for treating diseases and disorders
US13/667,578 2012-11-02
US13/667,578 US9006172B2 (en) 2011-11-02 2012-11-02 Peptide analogs for treating diseases and disorders

Publications (2)

Publication Number Publication Date
CN103998052A CN103998052A (zh) 2014-08-20
CN103998052B true CN103998052B (zh) 2016-08-17

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280062729.0A Expired - Fee Related CN103998052B (zh) 2011-11-02 2012-11-02 用于治疗疾病和紊乱的肽类似物

Country Status (10)

Country Link
US (1) US9006172B2 (cg-RX-API-DMAC7.html)
JP (3) JP6170933B2 (cg-RX-API-DMAC7.html)
KR (1) KR102019911B1 (cg-RX-API-DMAC7.html)
CN (1) CN103998052B (cg-RX-API-DMAC7.html)
AU (2) AU2012332265B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014010701A2 (cg-RX-API-DMAC7.html)
CA (1) CA2854175A1 (cg-RX-API-DMAC7.html)
MX (1) MX351092B (cg-RX-API-DMAC7.html)
RU (1) RU2616511C2 (cg-RX-API-DMAC7.html)
WO (1) WO2013067357A1 (cg-RX-API-DMAC7.html)

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GB201500263D0 (en) * 2015-01-08 2015-02-25 Keybioscience Ag Calcitonin analogues for treating diseases and disorders
GB201704429D0 (en) 2017-03-21 2017-05-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201707955D0 (en) 2017-05-18 2017-07-05 Keybioscience Ag Dual amylin and calcitonin receptor agonists for treating diseases and disorders
GB201813678D0 (en) * 2018-08-22 2018-10-03 Keybioscience Ag Acylated calcitonin mimetics
GB201813677D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
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Also Published As

Publication number Publication date
JP6170933B2 (ja) 2017-07-26
JP2018135360A (ja) 2018-08-30
CN103998052A (zh) 2014-08-20
JP2017061500A (ja) 2017-03-30
AU2016247189A1 (en) 2016-11-10
KR20140093967A (ko) 2014-07-29
NZ625215A (en) 2016-04-29
JP2014532722A (ja) 2014-12-08
MX2014005265A (es) 2014-10-13
MX351092B (es) 2017-10-02
JP6330013B2 (ja) 2018-05-23
AU2016247189B2 (en) 2017-09-14
JP6547034B2 (ja) 2019-07-17
US9006172B2 (en) 2015-04-14
US20130183385A1 (en) 2013-07-18
CA2854175A1 (en) 2013-05-10
BR112014010701A2 (pt) 2020-06-23
AU2012332265B2 (en) 2016-11-10
AU2012332265A1 (en) 2014-06-05
KR102019911B1 (ko) 2019-09-09
RU2616511C2 (ru) 2017-04-17
WO2013067357A1 (en) 2013-05-10
RU2014122171A (ru) 2015-12-10

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Granted publication date: 20160817

Termination date: 20191102

CF01 Termination of patent right due to non-payment of annual fee