CN103977107A - Traditional Chinese medicine composition for treating leucoderma - Google Patents
Traditional Chinese medicine composition for treating leucoderma Download PDFInfo
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- CN103977107A CN103977107A CN201410235188.8A CN201410235188A CN103977107A CN 103977107 A CN103977107 A CN 103977107A CN 201410235188 A CN201410235188 A CN 201410235188A CN 103977107 A CN103977107 A CN 103977107A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating leucoderma. The traditional Chinese medicine composition comprises the following traditional Chinese medicines in parts by weight: hematoxylon, motherwort seed, periostracum cicada, polygonum multiflorum, sulphur, cinnabar, borneol, ophidian, flowers carthami, eclipta alba, smoked plum, radix salviae miltiorrhizae and honey. The traditional Chinese medicines are blended with honey after being crushed, and topically applied to an affected part, the medicines enter a human body through skin tissues to treat both symptoms and root causes, and have the effects of invigorating the circulation of blood and dispelling the wind, dehumidifying, clearing heat and relieving itching, tonifying the liver and kidneys, restoring menstrual flow and activating collaterals, and restoring skin pigment, the symptoms such as local skin whitening and pruritus caused by disappearance of melanocyte are radically resolved, the complications such as scleroderma, diabetes, pernicious anemia and cancers can be prevented, finally the target of curing the leucoderma is achieved, and regeneration of human body melanin is achieved.
Description
Technical field
The invention belongs to the field of Chinese medicines, a kind ofly specifically treat leukodermic Chinese medicine composition.
Background technology
At present, vitiligo is the de-disease of losing of a kind of common skin pigment posteriority, being the symptom being caused by the melanocyte defunctionalization on skin, all likely there is this disease in each position of whole body, is common in the back of the hand, arm, face, cervical region, genitals etc. around.
At the clinical skin that shows as, become milky or lightpink, smooth surface is without erythra, and day shift, boundary was clear; the intensification to some extent of edge pigment compared with normal; the hair in affected part is normal or bleach, and how symmetrical affected part is, specifically can be divided into the type of being dispersed in, topical type and general hair style.Vitiligo morbidity Gender no significant difference, each age group all can be fallen ill, but teenager is more easily fallen ill, and the many no conscious symptons of patient, small number of patients has scratchiness in part in premorbid or morbidity, usually with other conscious immune disease, as scleroderma, atoipc dermatitis, alopecia areata etc.
The leukodermic patient's number of China is all increasing every year, and current most of patient's therapeutic effect is not very desirable, and majority is cured the symptoms, not the disease, and is easy to recurrence.What Chinese medicine was focused on all the time fundamentally removes disease exactly, therefore vitiligo is treated from Chinese medicine angle, is one of effectively Therapeutic Method.
Summary of the invention
The problem to be solved in the present invention is for above problem, and a kind of leukodermic Chinese medicine composition for the treatment of is provided.What this invention adopted is tcm theory, and the method with external application, is directly applied to affected part, has good therapeutic effect.
For addressing the above problem, the technical solution adopted in the present invention is:
Treat a leukodermic Chinese medicine composition, it is characterized in that, described Chinese medicine composition comprises the Chinese medicine of following weight portion:
Lignum Sappan 10-20 gram, Fructus Leonuri 10-20 gram, Periostracum Cicadae 5-10 gram, Radix Polygoni Multiflori 5-10 gram, sulfur 5-10 gram, Cinnabaris 8-12 gram, Borneolum Syntheticum 3-8 gram, ophidia 5-15 gram, Flos Carthami 8-12 gram, Herba Ecliptae 10-20 gram, Fructus Mume 5-10 gram, Radix Salviae Miltiorrhizae 5-10 gram, Mel 100-200 gram.
As a kind of prioritization scheme:
Described Chinese medicine composition comprises the Chinese medicine of following weight portion:
20 grams of Lignum Sappans, 20 grams of Fructus Leonuri, 8 grams of Periostracum Cicadaes, 10 grams of Radix Polygoni Multiflori, 5 grams, sulfur, 8 grams, Cinnabaris, 3 grams of Borneolum Syntheticums, 5 grams of ophidias, 8 grams, Flos Carthami, 20 grams of Herba Ecliptaes, 8 grams of Fructus Mumes, 5 grams of Radix Salviae Miltiorrhizae, 150 grams of Mel.
As a kind of prioritization scheme:
Described Chinese medicine composition comprises the Chinese medicine of following weight portion:
20 grams of Lignum Sappans, 15 grams of Fructus Leonuri, 10 grams of Periostracum Cicadaes, 10 grams of Radix Polygoni Multiflori, 8 grams, sulfur, 10 grams, Cinnabaris, 4 grams of Borneolum Syntheticums, 5 grams of ophidias, 8 grams, Flos Carthami, 20 grams of Herba Ecliptaes, 5 grams of Fructus Mumes, 5 grams of Radix Salviae Miltiorrhizae, 150 grams of Mel.
As a kind of prioritization scheme:
Described Chinese medicine composition comprises the Chinese medicine of following weight portion:
15 grams of Lignum Sappans, 15 grams of Fructus Leonuri, 10 grams of Periostracum Cicadaes, 10 grams of Radix Polygoni Multiflori, 5 grams, sulfur, 10 grams, Cinnabaris, 5 grams of Borneolum Syntheticums, 8 grams of ophidias, 10 grams, Flos Carthami, 15 grams of Herba Ecliptaes, 5 grams of Fructus Mumes, 7 grams of Radix Salviae Miltiorrhizae, 150 grams of Mel.
Wherein:
Lignum Sappan is a kind of clinical conventional Chinese medicine, can invigorate blood circulation and cure the wound, treatment tetanus, because of symptoms such as skin ulcer apoplexy, its property is sweet, one-tenth, pungent.Decoction or grind in right amount outer clothes into powder can.
The main effect of Fructus Leonuri is blood circulation promoting and blood stasis dispelling, and acrid in the mouth tepor is gynecological's conventional Chinese medicine.
The disease such as Periostracum Cicadae is mainly used in dispelling wind heat, skin pruritus, rubella pruritus, rash sore-throat relieving, expelling wind and relieving convulsion.Periostracum Cicadae be the larva of Cicadae to become adult be the shell taking off, be rich in the compositions such as protein, aminoacid, organic acid, phenols, saccharide, oils and fats, cold in nature nontoxic, can external application also can do decoction.
Radix Polygoni Multiflori is for blood deficiency, Liver and kidney blood and essence asthenia, early whitening of beard and hair, rubella pruritus etc.
Sulfur belongs to low toxicity hazardous chemicals, sulfur and contact skin generate hydrogen sulfide under body temperature condition, kill microorganism or Epithelial cell on skin, if be oxidized to pentathionic acid, also have fungicidal effect, the effect that can dissolve cutin or depilation, can be used for treating for skin disease.
Cinnabaris is a kind of cinnabar mineral of redness, has severe toxicity, and the removing toxic substances that can be used for calming the nerves, epilepsy are gone mad, aphtha, skin infection swell and ache etc.
Borneolum Syntheticum is that water white transparency body or white are translucent, gas delicate fragrance, acrid in the mouth, poisonous.The effect with the refreshment of having one's ideas straightened out, heat-clearing and toxic substances removing, improving acuity of vision and removing nebula, cures mainly that calentura, unconsciousness due to high fever, apoplexy syncope due to accumulation of phlegm infantile convulsion, heat-damp in summer are hoodwinked clearly key, sore throat is deaf, aphtha tooth is swollen, carbuncle sore infantile malnutrition hemorrhoid, conjunctival congestion and swelling pain, pterygium.
Ophidia is commonly called as Zaocys, belong to the nonpoisonous snake that build is larger, the effect with wind-damp dispelling, the meridian dredging, relieving spasm by subduing liver-wind, anti-itch detoxification, for the treatment of the symptoms such as rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Flos Carthami is annual herb plant, gets its flower and is used as medicine, and has that latus rectum is invigorated blood circulation, the effect of blood stasis removing pain relieving, cures mainly gynaecopathia and speckle, rash etc.
Herba Ecliptae, for nourishing the medicine of convergence, has the merit of astringing to arrest bleeding evacuation of pus, can control the diseases such as various haematemesis, enterorrhagia.Smash juice painting eyebrow and send out, can promote hair growth, also have the effect of black hair, hair color, recovery skin pigment.
Fructus Mume, containing citric acid, malic acid, succinic acid, carbohydrate, sitosterol, ceroidlike material and oleanolic acid sample material, is mainly used to treat the symptoms such as skin pruritus, psoriasis, neurasthenia, achlorhydria, chronic nephritis.
Radix Salviae Miltiorrhizae perennial vertical herbage plant, its root is used as medicine, and contains TANSHINONES composition, is robustness emmenagogue, has blood stasis dispelling, tissue regeneration promoting, invigorates blood circulation, the effectiveness such as regulating menstruation.
Preparation and application: Lignum Sappan, Fructus Leonuri, Periostracum Cicadae, Radix Polygoni Multiflori, sulfur, Cinnabaris, Borneolum Syntheticum, ophidia, Flos Carthami, Herba Ecliptae, Fructus Mume, Radix Salviae Miltiorrhizae are made to powder and are in harmonious proportion with Mel, be applied to affected part, external application in every eight hours once, seven days courses for the treatment of.
The traditional Chinese medical science is thought, leukodermic morbidity is the synergistic result of body internal and external factor, in because liver spleen suffer from a deficiency of the kidney, how by deficiency of liver-blood, insufficiency of kidney-YANG, deficiency of kidney-QI, cause and make body yin and yang imbalance, qi-blood disharmony, damp and hot ailment said due to cold or exposure is taken advantage of a weak point on this basis, visitor enters skin, impatency meridians blood vessels, skin must not be warm, and skin and hair loses foster blackening depigmentation and forms white macula.
Medicine of the present invention enters in skin histology by skin surface, can get through meridians and the blood vessels of impatency, promoting blood circulation by removing wind, the antipyretic and itching-stopping that dehumidifies, that skin is obtained is warm, recover dermal melanin, and then the object for the treatment of both the principal and secondary aspects of a disease, fundamentally solve and because of melanocytic disappearance, cause the symptoms such as the local colour of skin bleaches, pruritus, and prevent the generation of the complication such as scleroderma, diabetes, pernicious anemia, malignant tumor, finally reach leukodermic healing object, and be difficult for recurrence.
The present invention is according to the pharmacology of above-mentioned Chinese medicine composition, and clinical trial for several times, to blue or green, in, the topical type of old all ages and classes section, be dispersed in type, generalized vitiligo patient, there is obvious therapeutic effect.
For clinical efficacy and the safety of individual better investigation Chinese medicine composition of the present invention, we have selected 120 routine patients to carry out clinical trial with the therapeutic effect of Chinese medicine composition of the present invention.
120 routine patients are divided into two groups at random, every group of 60 examples, matched group male 35 examples, women's 25 examples; Treatment group male's 28 examples, women's 32 examples, sick time one to three year.
Two groups of cases are Epidemiological Analysis by statistics at aspects such as sex, the courses of disease, have comparability, all cases are all diagnosed with reference to leukodermic diagnostic criteria in < < skin nursing > >.
Matched group adopts current common Therapeutic Method, and patient generally takes prescribed drug Meladinine at present, and one day twice, treatment time was one month, treatment group external application Chinese medicine composition of the present invention, and every eight hours are once, and treatment time is one month.
Criterion of therapeutical effect;
Cure---the colour of skin is dimmed, and without scratchiness, affected part hair is normal;
Effective---the colour of skin is dimmed, has once in a while scratchiness, and affected part hair is normal;
Effectively---the colour of skin is dimmed to some extent, also often has scratchiness, and affected part hair turns white;
Invalid---colour of skin milky, with scratchiness, affected part hair turns white;
Concrete data as shown in Table 1.
Table one
| Group | Number of cases | Cure n (%) | Effective n (%) | Effective n (%) | Invalid n (%) | Relapse rate n (%) |
| Matched group | 60 | 38(63.3) | 45(75.0) | 50(83.3) | 10(16.6) | 18(30.0) |
| Treatment group | 60 | 55(91.7) | 58(96.7) | 60(100) | 0(0) | 3(0.5) |
By the contrast of above-mentioned table one, the cure rate that can find out Chinese medicine composition of the present invention is high, therapeutic effect is remarkable, with with Western medicine Meladinine, compare, not only total effective rate is higher than Western medicine, and can treating both the principal and secondary aspects of a disease, makes the melanic regeneration of human body recover normal, fundamentally cure vitiligo, be difficult for recurrence.
The specific embodiment
Embodiment 1: a kind ofly treat leukodermic Chinese medicine composition, described Chinese medicine composition is comprised of 150 grams of 20 grams of Lignum Sappans, 20 grams of Fructus Leonuri, 8 grams of Periostracum Cicadaes, 10 grams of Radix Polygoni Multiflori, 5 grams, sulfur, 8 grams, Cinnabaris, 3 grams of Borneolum Syntheticums, 5 grams of ophidias, 8 grams, Flos Carthami, 20 grams of Herba Ecliptaes, 8 grams of Fructus Mumes, 5 grams of Radix Salviae Miltiorrhizae, Mel, above-mentioned Chinese herb is made after powder, add that Mel reconciles into pasty state external application, every eight hours once, it within seven days, is a course for the treatment of, just can cure three to four courses for the treatment of, within two to three months, reappears the normal colour of skin.
Embodiment 2: a kind ofly treat leukodermic Chinese medicine composition, described Chinese medicine composition is comprised of 150 grams of 20 grams of Lignum Sappans, 15 grams of Fructus Leonuri, 10 grams of Periostracum Cicadaes, 10 grams of Radix Polygoni Multiflori, 8 grams, sulfur, 10 grams, Cinnabaris, 4 grams of Borneolum Syntheticums, 5 grams of ophidias, 8 grams, Flos Carthami, 20 grams of Herba Ecliptaes, 5 grams of Fructus Mumes, 5 grams of Radix Salviae Miltiorrhizae, Mel, above-mentioned Chinese herb is made after powder, add that Mel reconciles into pasty state external application, every eight hours once, it within seven days, is a course for the treatment of, just can cure three to four courses for the treatment of, within two to three months, reappears the normal colour of skin.
Embodiment 3: a kind ofly treat leukodermic Chinese medicine composition, described Chinese medicine composition is comprised of 150 grams of 15 grams of Lignum Sappans, 15 grams of Fructus Leonuri, 10 grams of Periostracum Cicadaes, 10 grams of Radix Polygoni Multiflori, 5 grams, sulfur, 10 grams, Cinnabaris, 5 grams of Borneolum Syntheticums, 8 grams of ophidias, 10 grams, Flos Carthami, 15 grams of Herba Ecliptaes, 5 grams of Fructus Mumes, 7 grams of Radix Salviae Miltiorrhizae, Mel, above-mentioned Chinese herb is made after powder, add that Mel reconciles into pasty state external application, every eight hours once, it within seven days, is a course for the treatment of, just can cure three to four courses for the treatment of, within two to three months, reappears the normal colour of skin.
Some patients were healing case is as follows:
King XX, female, 23 years old, urban district, Shouguang City, suffered from vitiligo 5 years, and for being dispersed in type patient, life-time service Western medicine cream, though can control scratchiness, does not have large-area diffusion yet, does not cure always.Use Chinese medicine composition of the present invention after four courses for the treatment of, the affected part colour of skin has remarkable improvement, reappears the normal colour of skin after three months, also not recurrence always after drug withdrawal.
Open XX, man, 30 years old, Weicheng District, Weifang City, suffer from vitiligo 2 years, belong to topical type patient, oral western medicine always, without remarkable improvement, sometimes pruritus hurt like hell, external application Chinese medicine composition of the present invention is after two courses for the treatment of, and scratchiness disappears, and after two months, reappears the normal colour of skin.
Lu XX, man, 45 years old, urban district, Shouguang City, just suffered from vitiligo one month, belongs to topical type patient, also there is no scratchiness, and external application Chinese medicine composition of the present invention is dimmed with regard to the colour of skin after the course for the treatment of, after one month, reappears the normal colour of skin, so far without recurrence.
Claims (4)
1. treat a leukodermic Chinese medicine composition, it is characterized in that: described Traditional Chinese drug mixture comprises the Chinese medicine of following weight portion:
Lignum Sappan 10-20 gram, Fructus Leonuri 10-20 gram, Periostracum Cicadae 5-10 gram, Radix Polygoni Multiflori 5-10 gram, sulfur 5-10 gram, Cinnabaris 8-12 gram, Borneolum Syntheticum 3-8 gram, ophidia 5-15 gram, Flos Carthami 8-12 gram, Herba Ecliptae 10-20 gram, Fructus Mume 5-10 gram, Radix Salviae Miltiorrhizae 5-10 gram, Mel 100-200 gram.
2. a kind of leukodermic Chinese medicine composition for the treatment of as claimed in claim 1, is characterized in that: described Traditional Chinese drug mixture comprises the Chinese medicine of following weight portion:
20 grams of Lignum Sappans, 20 grams of Fructus Leonuri, 8 grams of Periostracum Cicadaes, 10 grams of Radix Polygoni Multiflori, 5 grams, sulfur, 8 grams, Cinnabaris, 3 grams of Borneolum Syntheticums, 5 grams of ophidias, 8 grams, Flos Carthami, 20 grams of Herba Ecliptaes, 8 grams of Fructus Mumes, 5 grams of Radix Salviae Miltiorrhizae, 150 grams of Mel.
3. a kind of leukodermic Chinese medicine composition for the treatment of as claimed in claim 1, is characterized in that: described Traditional Chinese drug mixture comprises the Chinese medicine of following weight portion:
20 grams of Lignum Sappans, 15 grams of Fructus Leonuri, 10 grams of Periostracum Cicadaes, 10 grams of Radix Polygoni Multiflori, 8 grams, sulfur, 10 grams, Cinnabaris, 4 grams of Borneolum Syntheticums, 5 grams of ophidias, 8 grams, Flos Carthami, 20 grams of Herba Ecliptaes, 5 grams of Fructus Mumes, 5 grams of Radix Salviae Miltiorrhizae, 150 grams of Mel.
4. a kind of leukodermic Chinese medicine composition for the treatment of as claimed in claim 1, is characterized in that: described Traditional Chinese drug mixture comprises the Chinese medicine of following weight portion:
15 grams of Lignum Sappans, 15 grams of Fructus Leonuri, 10 grams of Periostracum Cicadaes, 10 grams of Radix Polygoni Multiflori, 5 grams, sulfur, 10 grams, Cinnabaris, 5 grams of Borneolum Syntheticums, 8 grams of ophidias, 10 grams, Flos Carthami, 15 grams of Herba Ecliptaes, 5 grams of Fructus Mumes, 7 grams of Radix Salviae Miltiorrhizae, 150 grams of Mel.
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Cited By (1)
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| CN107334881A (en) * | 2017-07-07 | 2017-11-10 | 王浩绪 | A kind of medicine for oral administration for treating leucoderma and preparation method thereof |
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