CN101874867B

CN101874867B - Chinese medicinal preparation for treating psoriasis

Info

Publication number: CN101874867B
Application number: CN201010186340XA
Authority: CN
Inventors: 李运祥
Original assignee: Individual
Current assignee: Individual
Priority date: 2010-05-31
Filing date: 2010-05-31
Publication date: 2011-09-21
Anticipated expiration: 2030-05-31
Also published as: CN101874867A

Abstract

The invention discloses a Chinese medicinal preparation for treating psoriasis and eczema. The Chinese medicinal preparation is prepared by processing a No.1 medicament and a No.2 medicament, wherein the No.1 medicament consists of virgate wormwood herb, Indian buead, skunk bugbane, baicalin, anemarrhena asphodeloides bunge, swordlike atractylodes rhizome, largehead atractylodes rhizome, oriental waterplantain rhizome, polyporus umbellatus, kudzu-vine root, lightyellow sophora root, root of red-rooted salvia, beautiful sweetgum fruit, garter snake, densefruit pittany root-bark, white paeony root, Chinese angelica and liquoric root; and the No.2 medicament consists of officinal magnolia bark, tuber fleeceflower root, Manchurian wildginger, prepared common monkshood mother root, prepared kusnezoff monkshood root, fineleaf schizonepeta herb, divaricate saposhnikovia root, szechuan lovage rhizome, incised notopterygium rhizome root, dendrobium, ephedra herb, scorpion, dahurian angelica root and radix glycyrrhizae preparata. The No.1 medicament and the No.2 medicament are dried or baked respectively, and are prepared into fine powder for encapsulation to prepare the Chinese medicinal preparation for treating psoriasis, namely a No.1 capsule and a No.2 capsule. The Chinese medicinal preparation has the advantages of convenient preparation, convenient carrying, convenient administration, low cost, no toxic or side effect and the like, and has excellent curative effect of treating psoriasis, eczema and the like.

Description

Medicament in the treatment psoriasis

Technical field

The present invention is a pure Chinese medicinal preparation, belongs to the field of Chinese medicines, for the treatment psoriasis curative effect is preferably arranged.

Background technology

Psoriasis; former title psoriasis; be a kind of common; refractory; and the chronic dermatosis of easy recurrence; the lighter influences its outer table image; then crisis life and health of weight person; bring ten minutes to seriously influence to people's work life and spirit; at present the research of its cause of disease still there is not final conclusion; think exopathogenic factor and rheumatism; hot worm invasion and attack spleen lung two warps; endogenous cause of ill and body's immunity; inherited genetic factors; Nervous and Mental Factors etc. are relevant, at present; the western medical treatment psoriasis, the endo-medicine aspect; comprise antineoplastic agent; retinoid medicine and immunosuppressant-regulator; but these curative effect of medication are fast, end-of-dose failure, and long-term prescription all can produce serious toxic and side effects.The Chinese traditional treatment psoriasis, though toxic and side effects is slightly little, good especially Chinese medicine preparation also is of no curative effect at present.

Summary of the invention

In order to overcome above-mentioned disadvantage, the applicant on the basis of handed down from the older generations of the family prescription, study assiduously, have the courage to bring forth new ideas, through the clinical practice invention prescription of more than ten years, update, invent out a kind of middle medicament of the usefulness for treatment psoriasis, eczema.

The present invention is processed by No. 1 medicine and No. 2 medicines, and No. 1 medicine and No. 2 medicines are constructed as follows respectively:

No. 1 medicine: Herba Artemisiae Scopariae 7-12g, Poria 9-14g, Rhizoma Cimicifugae 6-12g, Radix Scutellariae 7-10g, Rhizoma Anemarrhenae 6-10g Rhizoma Atractylodis 10-30g, Rhizoma Atractylodis Macrocephalae 7-12g, Rhizoma Alismatis 8-13g, Polyporus 7-11g, Radix Puerariae 7-12g, Radix Sophorae Flavescentis 7-16g, Radix Salviae Miltiorrhizae 7-10g, Fructus Liquidambaris 7-10g, Zaocys 5-10g, favus skin 8-15g, Radix Paeoniae Alba 6-9g, Radix Angelicae Sinensis 6-10g, Radix Glycyrrhizae 6-9g;

No. 2 medicine: Cortex Magnoliae Officinalis 10-18g, Radix Polygoni Multiflori 7-12g, Herba Asari 4-9g, Radix Aconiti Preparata 7-12g, Radix Aconiti Kusnezoffii Preparata 7-12g, Herba Schizonepetae 7-9g, Radix Saposhnikoviae 7-9g, Rhizoma Chuanxiong 7-10g, Rhizoma Et Radix Notopterygii 5-8g, Herba Dendrobii 7-15g, Herba Ephedrae 7-10g, Scorpio 7-12g, Radix Angelicae Dahuricae 7-9g, Radix Glycyrrhizae Preparata 6-9g.

Above-mentioned No. 1 medicine, No. 2 medicines are put slow fire respectively and made popular to little Huang, and take out the oven dry back; Or raw material is seated in respectively around the stove, one deck toilet paper baking in lower berth is dried.No. 1 medicine, No. 2 medicines of handling through said method, mix homogeneously separately is developed into fine powder more respectively after cooling, crosses 100 mesh sieves, encapsulated then, every capsules weighs 0.4 gram, makes No. 1 capsule and No. 2 capsules, promptly make treatment psoriatic in medicament.

Instructions of taking, early, No. 1 capsule 4-8 grain of noon clothes, eliminating cold for resuscitation water send down, obeys capsule 4-8 grain evening No. 2, and yellow wine send down.

Taboo: period in a medicine: the thing of stimulation such as fasting suffering, peppery, raw and cold seafood, avoid liquor, save sexual life, be not taken by pregnant women.

Of the present invention above-mentioned in medicament have nourish blood, effect that detoxifcation was dispeled the wind, invigorates blood circulation, dispersed in heat clearing away, dampness removing parasite killing.The present invention is easy to make, and is easy to carry, and taking convenience is with low cost, and has advantage such as have no side effect, and to diseases such as treatment psoriasis, eczemas, good especially curative effect arranged.

That medium-height grass prescription of the present invention has is easy to make, the medicine source is wide, cost is low, the advantage of good effect.

The specific embodiment

Below be the main pharmacology analysis of used medical material:

The main pharmacology of No. 1 medicine: Herba Artemisiae Scopariae, clearing away heat-damp and promoting diuresis, skin ulcer is treated in detoxifcation; Polyporus, inducing diuresis to remove edema; Rhizoma Alismatis, inducing diuresis to remove edema, diuresis and eliminating dampness by diuresis is purged heat; The Rhizoma Anemarrhenae, Radix Scutellariae, the detoxifcation of purging heat, heat clearing and damp drying, assistant is with the Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, the spleen strengthening and damp drying, and spleen is good for transported of damp; Radix Sophorae Flavescentis, favus skin, heat clearing and damp drying parasite killing, the detoxifcation of dispeling the wind is mainly used in warm sore, eczema scabies, jaundice due to damp-heat, rheumatism pyretic arthralgia etc.; The Radix Paeoniae Alba, the empty the moon of hemostasis lose easing the affected liver to relieve pain; Rhizoma Cimicifugae, the rash of inducing sweat, heat-clearing and toxic substances removing; Radix Puerariae, rise the taste Qingyang to disperse damp, expelling pathogenic factors from muscles for reducing heat, rash; Radix Angelicae Sinensis, enrich blood and invigorate blood circulation, nourishing blood for regulating menstruation, the anti-bitter dry product impairment of YIN blood that oozes profit of astringing YIN to stop sweating; Poria, inducing diuresis to remove edema, eliminating dampness by diuresis, spleen invigorating, mind tranquilizing and the heart calming; Zaocys, dispelling wind and removing obstruction in the collateral, detoxicating and resolving stagnation of pathogens; Fructus Liquidambaris, dispelling, collateral-activating, diuretic stimulates the menstrual flow; Radix Salviae Miltiorrhizae, vital energy regualting and blood circulation-promoting, eliminating carbuncle,, stasis-dispelling and pain-killing, removing heat from blood, relieving restlessness is calmed the nerves; Radix Glycyrrhizae, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription, all medicine phases 5, clearing away heat-damp and promoting diuresis, eliminating pathogens by phlegm elimination and purgation respectively, ascending the clear and descending the turbid, nourishing blood for regulating menstruation, invigorating the spleen and regulating the stomach, QI and blood is along logical, and skin is with smooth.

The main pharmacology of No. 2 medicines:

Radix Polygoni Multiflori, removing toxicity for eliminating carbuncles, the rash of dispeling the wind pruritus; The Radix Angelicae Dahuricae, expelling wind and cold, detumescence and apocenosis; Herba Ephedrae, Xin Wen, space between skin and muscles is led in diaphoresis, opens skin, inducing diuresis to remove edema, blood circulation regulating; Herba Schizonepetae, expelling pathogenic wind from the body surface, the rash skin ulcer that disappears is mainly used in the diseases caused by exogenous pathogenic factor exterior syndrome, the rubella pruritus, and skin infection is from the beginning of having exterior syndrome concurrently; Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, expelling pathogenic wind from the body surface, removing dampness to relieve pain, the ailment said due to cold or exposure of loosing, the skin ulcer that disappears is swollen; Scorpio, dispersing pathogen accumulation removing obstruction in the collateral to relieve pain are searched wind, and detoxifcation again can mass dissipating and swelling eliminating; Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, warm cold expelling wet, the detoxifcation of dispeling the wind, and dampness is suppurated, detumescence; Cortex Magnoliae Officinalis, dampness leukorrhagia stopping, therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO; Herba Asari, Wen Han have one's ideas straightened out, the cold expelling that induces sweat, wind-expelling pain-stopping; Herba Dendrobii, the hot yin nourishing that disappears are promoted the production of body fluid; Rhizoma Chuanxiong, blood-activating and qi-promoting, wind-expelling pain-stopping, detumescence; Radix Glycyrrhizae Preparata, reinforce functional activities of the heart are agitated blood vessels, the usefulness of coordinating the actions of various ingredients in a prescription.

All medicines share can play diffusing wind, damp eliminating, invigorate blood circulation, detoxify, treat skin ulcer itching relieving effect.

Treat psoriatic Chinese medicinal formulae for the present invention, to the psoriatic of different syndromes, when making capsule, wherein the proportioning of each medical material is incomplete same.

(1), heavy light psoriatic of summer of winter, belong to wind plug noxious dampness type, its feature compatibility is:

No. 1 medicine: Herba Artemisiae Scopariae 7g, Poria 10g, Rhizoma Cimicifugae 9g, Radix Scutellariae 6g, Rhizoma Anemarrhenae 6g, Rhizoma Atractylodis 20g, Rhizoma Atractylodis Macrocephalae 10g, Rhizoma Alismatis 8g, Polyporus 8g, Radix Puerariae 10g, Radix Sophorae Flavescentis 13g, Radix Salviae Miltiorrhizae 10g, Fructus Liquidambaris 8g, Zaocys 10g, favus skin 13g, Radix Paeoniae Alba 7g, Radix Angelicae Sinensis 10g, Radix Glycyrrhizae 6g;

No. 2 medicine: Cortex Magnoliae Officinalis 15g, Radix Polygoni Multiflori 8g, Herba Asari 7g, Radix Aconiti Preparata 10g, Radix Aconiti Kusnezoffii Preparata 10g, Herba Schizonepetae 8g, Radix Saposhnikoviae 8g, Rhizoma Chuanxiong 8g, Rhizoma Et Radix Notopterygii 7g, Herba Dendrobii 10g, Herba Ephedrae 8g, Scorpio 10g, Radix Angelicae Dahuricae 7g, Radix Glycyrrhizae Preparata 7g

(2), heavy psoriatic of light summer in winter, belong to the strongly fragrant malicious type of wind heat, its feature compatibility is:

No. 1 medicine: Herba Artemisiae Scopariae 12g, Poria 10g, Rhizoma Cimicifugae 9g, Radix Scutellariae 10g, Rhizoma Anemarrhenae 10g, Rhizoma Atractylodis 10g, Rhizoma Atractylodis Macrocephalae 10g, Rhizoma Alismatis 8g, Polyporus 8g, Radix Puerariae 10g, Radix Sophorae Flavescentis 15g, Radix Salviae Miltiorrhizae 8g, Fructus Liquidambaris 8g, Zaocys 10g, favus skin 15g, Radix Paeoniae Alba 9g, Radix Angelicae Sinensis 10g, Radix Glycyrrhizae 8g;

No. 2 medicines: its feature compatibility is: Cortex Magnoliae Officinalis 10g, Radix Polygoni Multiflori 8g, Herba Asari 4g, Radix Aconiti Preparata 7g, Radix Aconiti Kusnezoffii Preparata 7g, Herba Schizonepetae 7g, Radix Saposhnikoviae 7g, Rhizoma Chuanxiong 8g, Rhizoma Et Radix Notopterygii 5g, Herba Dendrobii 5g, Herba Ephedrae 8g, Scorpio 10g, Radix Angelicae Dahuricae 9g, Radix Glycyrrhizae Preparata 8g

(3), spring and autumn heavy psoriatic, belong to blood deficiency, heat stagnation pathogenic wind toxic type, its feature compatibility is:

No. 1 medicine: Herba Artemisiae Scopariae 10g, Poria 10g, Rhizoma Cimicifugae 9g, Radix Scutellariae 9g, Rhizoma Anemarrhenae 9g, Rhizoma Atractylodis 15g, Rhizoma Atractylodis Macrocephalae 8g, Rhizoma Alismatis 10g, Polyporus 10g, Radix Puerariae 12g, Radix Sophorae Flavescentis 16g, Radix Salviae Miltiorrhizae 10g, Fructus Liquidambaris 10g, Zaocys 10g, favus skin 10g, Radix Paeoniae Alba 9g, Radix Angelicae Sinensis 10g, Radix Glycyrrhizae 7g

No. 2 medicine: Cortex Magnoliae Officinalis 12g, Radix Polygoni Multiflori 12g, Herba Asari 5g, Radix Aconiti Preparata 8g, Radix Aconiti Kusnezoffii Preparata 8g, Herba Schizonepetae 9g, Radix Saposhnikoviae 9g, Rhizoma Chuanxiong 10g, Rhizoma Et Radix Notopterygii 6g, Herba Dendrobii 12g, Herba Ephedrae 10g, Scorpio 12g, Radix Angelicae Dahuricae 9g, Radix Glycyrrhizae Preparata 9g

Be the example of treatment case of the present invention below:

1. women patient, 30 years old, Gao Gu people from village of Hebei province's Handan District Yongnian County.Psoriasis morbidity 4 years through the various big hospital treatment, is not got better and is changeed the back to the here diagnosis and treatment.Patient's readme is itched heavily night, and annual spring and autumn is heavy, skin lesion chestnut point, drop, the strong color of piece sheet are red, on cover white silver bits, nervous, and menstrual phase has significant reaction.Head and extremity distribute many, and red tongue is light, wet, yellow and thin fur, moderate pulse, card genus, blood deficiency, damp and hot, pathogenic wind toxic.Went home to take 20 days with No. 1, No. 2 capsules, respectively obey 6 at every turn by above-mentioned instructions about how to take medicine.Come further consultation, the erythra desalination, erythema disappears, and does not have projection, itches night and does not gently see new erythra.Medication one month is continued in the back, and patient's erythra disappears substantially, the elimination of scratching where it itches, and can sleep peacefully night, and the patient requires to take medicine 60 days again, continues medication.Further consultation for the third time after medicine takes, patient's erythra are all moved back only, only stay dim pigment, and other symptoms all disappear, so far not recurrence.

2. male patient, 36 years old, Yang Fan people from village in Xingtai suffered from psoriasis 6 years, and winter-spring season is serious, and summer is lighter, once, began to take a favourable turn in the various big hospital treatment, but the very fast recurrence of drug withdrawal, and more serious.After do not see significant curative effect with the treatment of injection and aminopterin again yet.Patient's head, abdomen, face and extremity, the general rubescent maculopapule of whole body, loam cake is silvery white, and can not sleep evening as YUQIAN size white scales, and pruritus is serious.The patient goes to a doctor on March nineteen ninety-five 5, and medication 20 days is respectively obeyed 6 by above-mentioned instructions about how to take medicine at every turn, and pruritus is taken a favourable turn, and deflorescence is not obvious.After come to take medicine again, dosage, each 8 of each clothes.Come further consultation after 20 days again, erythra sees obviously and moves back that pruritus is eliminated, and the patient is confident to treating.Took medicine two months again.Came again June 15 to take medicine, erythra is all moved back and is only stayed the skin lesion pigment only, so far not recurrence.

3, male patient, Changzhuang people from village, Shahe City, Xingtai, psoriasis 3 years, once at Handan hospital hospitalization, Chinese medicine, Western medicine, simultaneously combined effect is not too obvious, after the diathermy of employing therapy is arranged, do not have positive effect yet.Because of the chest diathermy often, leave peony and exceed the skin speckle.On May 4th, 2008, head, trunk, extremity all had erythra at that time, covered white scales on the erythra to my clinic treatment.Erythra is scratched where it itches seriously, and xerostomia feeling of fullness in the head, stomach poor appetite are not had enough sleep, and be listless.The patient has the phychology of trying in arms and took medicine 20 days, and May 24 went to a doctor again, and extremity face erythra sees and move back that scratching where it itches alleviates, and has the position of chest diathermy only, not too obvious.Advise patient's dosage of taking medicine again, each 8 of each clothes.Come further consultation after 20 days again, the chest erythra obviously disappears, and medication is 30 days again, and erythra substantially all disappears.The patient continued medication three months, disease cured, and skin is intact smooth, and the patient requires to consolidate curative effect and obeys drug withdrawal in two months again, so far not recurrence.

Claims

A treatment psoriatic in medicament, it is characterized in that: medicament is each No. 1 capsule and No. 2 capsule that processed by No. 1 medicine and No. 2 medicines in this; No. 1 medicine and No. 2 medicines are constructed as follows respectively:

No. 1 medicine: Herba Artemisiae Scopariae 7-12g, Poria 9-14g, Rhizoma Cimicifugae 6-12g, Radix Scutellariae 7-10g, Rhizoma Anemarrhenae 6-10g, Rhizoma Atractylodis 10-30g, Rhizoma Atractylodis Macrocephalae 7-12g, Rhizoma Alismatis 8-13g, Polyporus 7-11g, Radix Puerariae 7-12g, Radix Sophorae Flavescentis 7-16g, Radix Salviae Miltiorrhizae 7-10g, Fructus Liquidambaris 7-10g, Zaocys 5-10g, favus skin 8-15g, Radix Paeoniae Alba 6-9g, Radix Angelicae Sinensis 6-10g, Radix Glycyrrhizae 6-9g;

No. 2 medicine: Cortex Magnoliae Officinalis 10-18g, Radix Polygoni Multiflori 7-12g, Herba Asari 4-9g, Radix Aconiti Preparata 7-12g, Radix Aconiti Kusnezoffii Preparata 7-12g, Herba Schizonepetae 7-9g, Radix Saposhnikoviae 7-9g, Rhizoma Chuanxiong 7-10g, Rhizoma Et Radix Notopterygii 5-8g, Herba Dendrobii 7-15g, Herba Ephedrae 7-10g, Scorpio 7-12g, Radix Angelicae Dahuricae 7-9g, Radix Glycyrrhizae Preparata 6-9g;

Above-mentioned No. 1 medicine, No. 2 medicines are put slow fire respectively and made popular to little Huang, and take out the oven dry back; Or raw material is seated in respectively around the stove, one deck toilet paper baking in lower berth is dried;

No. 1 medicine, No. 2 medicines of handling through said method, mix homogeneously separately is developed into fine powder more respectively after cooling, crosses 100 mesh sieves, encapsulated then, every capsules weighs 0.4 gram, be treatment psoriatic in medicament: No. 1 capsule and No. 2 capsules.
2. medicament during treatment according to claim 1 is psoriatic is characterized in that:

For heavy light psoriatic of summer of winter, belong to wind and cold noxious dampness type, its medicine constitutes:

No. 1 medicine: Herba Artemisiae Scopariae 7g, Poria 10g, Rhizoma Cimicifugae 9g, Radix Scutellariae 6g, Rhizoma Anemarrhenae 6g, Rhizoma Atractylodis 20g, Rhizoma Atractylodis Macrocephalae 10g, Rhizoma Alismatis 8g, Polyporus 8g, Radix Puerariae 10g, Radix Sophorae Flavescentis 13g, Radix Salviae Miltiorrhizae 10g, Fructus Liquidambaris 8g, Zaocys 10g, favus skin 13g, Radix Paeoniae Alba 7g, Radix Angelicae Sinensis 10g, Radix Glycyrrhizae 6g;

No. 2 medicine: Cortex Magnoliae Officinalis 15g, Radix Polygoni Multiflori 8g, Herba Asari 7g, Radix Aconiti Preparata 10g, Radix Aconiti Kusnezoffii Preparata 10g, Herba Schizonepetae 8g, Radix Saposhnikoviae 8g, Rhizoma Chuanxiong 8g, Rhizoma Et Radix Notopterygii 7g, Herba Dendrobii 10g, Herba Ephedrae 8g, Scorpio 10g, Radix Angelicae Dahuricae 7g, Radix Glycyrrhizae Preparata 7g.
3. medicament during treatment according to claim 1 is psoriatic is characterized in that:

For heavy psoriatic of light summer in winter, belong to the strongly fragrant malicious type of wind heat, its medicine constitutes:

No. 1 medicine: Herba Artemisiae Scopariae 12g, Poria 10g, Rhizoma Cimicifugae 9g, Radix Scutellariae 10g, Rhizoma Anemarrhenae 10g, Rhizoma Atractylodis 10g, Rhizoma Atractylodis Macrocephalae 10g, Rhizoma Alismatis 8g, Polyporus 8g, Radix Puerariae 10g, Radix Sophorae Flavescentis 15g, Radix Salviae Miltiorrhizae 8g, Fructus Liquidambaris 8g, Zaocys 10g, favus skin 15g, Radix Paeoniae Alba 9g, Radix Angelicae Sinensis 10g, Radix Glycyrrhizae 8g;

No. 2 medicine: Cortex Magnoliae Officinalis 10g, Radix Polygoni Multiflori 8g, Herba Asari 4g, Radix Aconiti Preparata 7g, Radix Aconiti Kusnezoffii Preparata 7g, Herba Schizonepetae 7g, Radix Saposhnikoviae 7g, Rhizoma Chuanxiong 8g, Rhizoma Et Radix Notopterygii 5g, Herba Dendrobii 5g, Herba Ephedrae 8g, Scorpio 10g, Radix Angelicae Dahuricae 9g, Radix Glycyrrhizae Preparata 8g.
4. medicament during treatment according to claim 1 is psoriatic is characterized in that: for heavy psoriatic in spring and autumn, belong to blood deficiency, heat stagnation pathogenic wind toxic type, its medicine constitutes:

No. 1 medicine: Herba Artemisiae Scopariae 10g, Poria 10g, Rhizoma Cimicifugae 9g, Radix Scutellariae 9g, Rhizoma Anemarrhenae 9g, Rhizoma Atractylodis 15g, Rhizoma Atractylodis Macrocephalae 8g, Rhizoma Alismatis 10g, Polyporus 10g, Radix Puerariae 12g, Radix Sophorae Flavescentis 16g, Radix Salviae Miltiorrhizae 10g, Fructus Liquidambaris 10g, Zaocys 10g, favus skin 10g, Radix Paeoniae Alba 9g, Radix Angelicae Sinensis 10g, Radix Glycyrrhizae 7g;

No. 2 medicine: Cortex Magnoliae Officinalis 12g, Radix Polygoni Multiflori 12g, Herba Asari 5g, Radix Aconiti Preparata 8g, Radix Aconiti Kusnezoffii Preparata 8g, Herba Schizonepetae 9g, Radix Saposhnikoviae 9g, Rhizoma Chuanxiong 10g, Rhizoma Et Radix Notopterygii 6g, Herba Dendrobii 12g, Herba Ephedrae 10g, Scorpio 12g, Radix Angelicae Dahuricae 9g, Radix Glycyrrhizae Preparata 9g.