CN107334881A - A kind of medicine for oral administration for treating leucoderma and preparation method thereof - Google Patents
A kind of medicine for oral administration for treating leucoderma and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of medicine for oral administration for treating leucoderma and preparation method thereof, belong to the field of Chinese medicines.The raw material that the medicine for oral administration includes has duckweed spirodela, tribulus terrestris, motherwort, the achene of Siberian cocklebur, Semen sesami nigrum, black fungus, the fruit of glossy privet, the root of Dahurain angelica, radix scrophulariae, zanthoxylum nitidum, kadsura longepedunculata, teasel, the fleece-flower root, gynostemma pentaphylla and Eclipta prostrata.The present invention successively carries out after different extraction processing that the Semen sesami nigrum with crushing, black fungus, the fleece-flower root mix again to the taste Chinese medicine of duckweed spirodela, tribulus terrestris etc. 12, obtained endo-medicine is directly oral, medicine property of medicine is remained as far as possible, improves the ageing and absorptivity of traditional Chinese medicine for oral administration.Each bulk drug compatibility is proper in the present invention, all medicines share, and energy is clearing heat and detoxicating, replenishes qi to invigorate the spleen, tonifies the liver and kidney, flat liver solution strongly fragrant, dispelling wind and removing obstruction in the meridians, expel endogenous wind to relieve convulsion, treats both principal and secondary aspect of disease, can recover dermal melanin, reaches the healing purpose to leucoderma, and uneasy to recur.
Description
Technical field
The invention belongs to the field of Chinese medicines, and in particular to a kind of medicine for oral administration for treating leucoderma and preparation method thereof.
Background technology
Leucoderma is the skin disease that a kind of limitation melanin is lost in, the typically no any subjective symptoms of patient, only in skin
Occur that size shape differs, number is indefinite, the clear hickie of boundary on skin, hickie can occur at any position, if occurring in head
Skin, eyebrow, eyelashes etc. can also make the hair at this bleach.Leucoderma slower development, when developing into certain phase can it is static not
Become, the consciousness of the white skin in affected part, secretion or excretory function are all normal, but poor compared with normal skin to the tolerance of ultraviolet irradiation.Mesh
Before, the cause of disease of leucoderma is not also fully aware of, it is considered that is due to that tegumentary chromatophore lacks Inhibition of Tyrosinase Activity skin
Metabolism of pigment, prevent tegumentary chromatophore from caused by producing melanin.
At present treatment leucoderma mainly there is medicine to control, physical treatment and operative treatment these three methods；Drug therapy includes
Oral drugs, such as psoralen and its derivative, vitamin, cupric medicine, this several method vitaminization cycle length, cupric
Drug side-effect is big, and some medicines such as psoralen and its derivative also need to coordinate ultraviolet irradiation treatment, to normal skin
Cause necessarily to damage；Physical treatment then needs to use narrow ripple ultraviolet, long wave ultraviolet or 308nm excimer laser treatments, right
Normal skin also has certain infringement, and above method can not all reach the purpose of healing；Operative treatment is then by intact dermatoplasty
To on outer skin, leucoderma can not be not only treated completely, and great pain is will also result in patient.
Traditional Chinese medical science leucoderma is referred to as vitiligo, it is believed that be by stagnation of liver qi, qi and blood it is not smooth, feel chill again, ailment said due to cold or exposure fight in skin,
Liver-kidney deficiency causes qi-blood disharmony, stagnation of blood stasis and fallen ill.So the treatment of leucoderma should with dispersing stagnated hepatoqi, tonify the liver and kidney based on,
And the methods of with promoting blood circulation and removing blood stasis, invigorating spleen and dispelling wind-evil.
The content of the invention
It is an object of the invention to provide a kind of medicine for oral administration for treating leucoderma and preparation method thereof.The present invention is closed by selecting
Suitable Chinese medicine compatibility, reach the purpose for safely and effectively curing leucoderma.
In order to achieve the above object, the present invention uses following technical scheme.
A kind of medicine for oral administration for treating leucoderma, include the raw material of following parts by weight：Duckweed spirodela 10-20 parts, tribulus terrestris 80-
120 parts, motherwort 15-25 parts, achene of Siberian cocklebur 10-20 parts, Semen sesami nigrum 25-35 parts, black fungus 25-35 parts, fruit of glossy privet 25-35 parts,
Root of Dahurain angelica 10-20 parts, radix scrophulariae 15-25 parts, zanthoxylum nitidum 15-25 parts, kadsura longepedunculata 25-35 parts, teasel 15-25 parts, the fleece-flower root
25-35 parts, gynostemma pentaphylla 25-35 parts, Eclipta prostrata 25-35 parts.
Preferably, the medicine for oral administration of the treatment leucoderma, includes the raw materials of following parts by weight：It is 15 parts of duckweed spirodela, white
It is 100 parts of puncture vine, 20 parts of motherwort, 15 parts of the achene of Siberian cocklebur, 30 parts of Semen sesami nigrum, 30 parts of black fungus, 30 parts of the fruit of glossy privet, 15 parts of the root of Dahurain angelica, profound
Ginseng 20 parts, 20 parts of zanthoxylum nitidum, 30 parts of kadsura longepedunculata, 20 parts of teasel, 30 parts of the fleece-flower root, 30 parts of gynostemma pentaphylla, Eclipta prostrata 30
Part.
The pharmacological property of each herbal medicine of medicine for oral administration of the present invention is as follows：
Duckweed spirodela：It is cold in nature, bitter；Enter lung channel；Effect：Sweating, wind-dispelling, water-filling, heat-clearing, removing toxic substances；Row heat during for controlling
Carbuncle, macula is impermeable, wind-heat pain rash, pruitus, oedema, Amenorrhea, sore tinea, erysipelas, scald.
Tribulus terrestris：It is bitter, pungent, it is mild-natured；Enter Liver Channel；Effect：Flat liver solution strongly fragrant, dispelling pathogenic wind for improving eyesight；Had a headache for dizziness due to hyperactivity of liver-YANG, liver
The diseases such as strongly fragrant hypochondriac pain, headache due to pathogenic wind-heat, red eye, swell pain, pruitus.
Motherwort：Bitter, pungent, cold nature；Return liver, pericardium, bladder warp；Effect：Promoting blood circulation for regulating menstruation, inducing diuresis to remove edema, heat-clearing solution
Poison；For irregular menstruation, dysmenorrhoea Amenorrhea, lochiorrhagia, oedema oliguria, sore swollen toxin.
The achene of Siberian cocklebur：It is bitter, sweet, pungent, it is warm-natured；Return lung, Liver Channel；Effect：Expelling cold, eliminating, clearing the nasal passage, wind-damp dispelling, analgesic；With
Demonstrate,proved in anemofrigid cold, nasosinusitis, arthralgia pain due to rheumatism, rubella itch etc..
Semen sesami nigrum：It is sweet, mild-natured, effect：It is nourishing liver and kidney, beneficial blood ease constipation, defaecation, promoting lactation.
Black fungus：It is sweet, it is mild-natured, enter stomach, liver, large intestine channel；Effect：Fill blood, stop blooding, moistening lung benefit stomach, moisturize sharp intestines, relax
Muscle is active, strong will of making light of one's life by commiting suicide；Lose, four limbs tic, cough due to deficiency of the lung, spit blood for deficiency of blood gas, spit blood, bleeding from five sense organs or subcutaneous tissue, puerperal asthenia, leukorrhea mistake
It is more, uterine bleeding, bloody flux, intestines wind hemorrhoid blood, the disease such as constipation and traumatic injury.
The fruit of glossy privet：It is sweet, bitter, it is cool in nature；Return liver and kidney channel；Effect：Tonify the liver and kidney, improving eyesight, clearind deficient heat；For having a dizzy spell,
Poliosis, blurring of vision, fever due to yin deficiency.
The root of Dahurain angelica：Acrid flavour, it is warm-natured；Return lung, spleen, stomach；Effect：Relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, clearing the nasal passage, eliminating dampness stops band, disappear
Swollen apocenosis, dispelling wind and arresting itching.For anemofrigid cold, headache, toothache, arthralgia pain due to rheumatism, nasosinusitis, with lower card, sore and toxic.
Radix scrophulariae：It is sweet, bitter, salty, cold nature；Returns spleen, stomach, kidney channel；Effect：Clearing heat and cooling blood, nourishing Yin and falling fire, detoxicating and resolving a mass；
For warm heat disease heat and ying blood, body heat, polydipsia, tongue is deep red, sends out spot, and hectic fever due to yin labor is coughed, dysphoria not awake, Tianjin hinder constipation, mesh is puckery dim-sighted, pharynx
Larynx larynx swells and ache, scrofula subcutaneous nodule, skin sore.
Zanthoxylum nitidum：It is bitter, pungent, it is mild-natured；Return liver, stomach；Effect：Dispelling wind and removing obstruction in the meridians, expel endogenous wind to relieve convulsion, subdhing swelling and detoxicating；For
Wind-cold-dampness arthralgia, arthralgia and myalgia, injury and bone fracture, colic, abscess of throat, have a stomach-ache, ascarid Jue stomachache, toothache, sore carbuncle scrofula, scald etc..
Kadsura longepedunculata：It is sour, sweet, it is warm-natured；Return lung, the heart, kidney channel；Effect：Restrain astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming；With
In empty asthma of coughing long, emission, enuresis frequent micturition, endless diarrhea, spontaneous sweating, injury thirst, Heat Diabetes, palpitation and insomnia.
Teasel：Bitter, pungent, slightly warm in nature；Return liver, kidney channel；Effect：Promoting circulation of blood is subsided a swelling, myogenic pain relieving, reunion of fractured tendons and bones, tonifying liver
Kidney, strong waist and knee, antiabortive, strengthening the bones and muscles, sharp joint, only uterine bleeding；It is first for soreness of waist and knee joint, rheumatic arthritis, fracture, traumatic injury
Megastream produces, uterine bleeding, vaginal discharge diseases, seminal emission, frequent micturition.
The fleece-flower root：Bitter but sweet flavor is puckery, slightly warm in nature；Enter liver and kidney channel；Effect：Nourishing the blood and yin, relax bowel, preventing malaria, wind-dispelling, solution
Poison；For deficiency of blood Light-headedness, palpitaition, insomnia, the soreness and weakness of waist and knees of the deficiency of liver-yin and kidney-yin, poliosis, tinnitus, pass out semen, dry constipation of intestines,
Chronic malaria body void, rubella itch, sore carbuncle, scrofula, hemorrhoid.
Gynostemma pentaphylla：Bitter, micro-sweet, it is cool in nature；Return lung, spleen, kidney channel；Effect：Replenish qi to invigorate the spleen, preventing phlegm from forming and stopping coughing is clearing heat and detoxicating；With
In physically weak weak, nephrasthenia emission, leukopenia, hyperlipidemia, virus hepatitis, chronic gastroenteritis, chronic bronchitis.
Eclipta prostrata：Sweet acid, it is cool in nature；Enter liver and kidney channel；Effect：Nourishing liver and kidney, cooling blood and hemostasis；For various haematemesis, nose goes out
The diseases such as blood, hemoptysis, enterorrhagia, hematuria, hemorrhoid hemorrhage, metrorrhagia are for oral administration to have black hair, dark hair effect.
The preparation method of the medicine for oral administration of the treatment leucoderma, comprises the following steps：
By duckweed spirodela, tribulus terrestris, motherwort, the achene of Siberian cocklebur, the fruit of glossy privet, the root of Dahurain angelica, radix scrophulariae, zanthoxylum nitidum, kadsura longepedunculata,
Teasel, gynostemma pentaphylla, Eclipta prostrata add water to cook 1-2h, and amount of water is 4-6 times of above-mentioned each medicine gross mass, is then separated by filtration
The dregs of a decoction and decoction, it is 1.20 (60 DEG C) thick pastes to be concentrated under reduced pressure into relative density, vacuum drying, crushed 80-120 mesh sieves, obtains
Chinese medicine water extraction fine powder；
(2) the step (1) gained dregs of a decoction are taken, add the ethanol solution refluxing extraction 1 time, time 1-2h that volumetric concentration is 50%,
The quality for adding 50% ethanol solution is 3-5 times of dregs of a decoction quality, is separated by filtration the dregs of a decoction and extract solution, extract solution is concentrated under reduced pressure into
Relative density is 1.20 (60 DEG C) thick pastes；
(3) the step (2) gained dregs of a decoction are taken, add the ethanol solution refluxing extraction 1 time, time 1-2h that volumetric concentration is 90%,
The quality for adding 90% ethanol solution is 3-5 times of dregs of a decoction quality, is separated by filtration the dregs of a decoction and extract solution, extract solution is concentrated under reduced pressure into
Relative density is 1.20 (60 DEG C) thick pastes；
(4) by step, (2) and (3) gained thick paste mixes, and vacuum drying, crushed 80-120 mesh sieves, it is thin to obtain Chinese medicine alcohol extracting
Powder；
(5) Semen sesami nigrum, black fungus, the fleece-flower root are crushed to 150-200 mesh respectively, obtained black sesame powder, black fungus powder,
Fleece-flower root powder mixes with Chinese medicine water extraction fine powder, Chinese medicine alcohol extracting fine powder, produces fine-powdered medicine for oral administration.
Usage and dosage：1 hour after meal oral fine-powdered medicine for oral administration of morning and evening daily, each 4-6g.
The advantageous effects of the present invention：(1) it is a kind of traditional extract oral side to take traditional Chinese medicine fine powder after directly crushing
Formula, although preparing simply, take fast, ageing and absorptivity is poor, and the present invention is to the taste of duckweed spirodela, tribulus terrestris etc. 12
Chinese medicine successively carries out after different extraction processing that the Semen sesami nigrum with crushing, black fungus, the fleece-flower root mix again, and obtained endo-medicine is straight
Interface takes, and not only overcomes disadvantages mentioned above, also remains medicine property of medicine as far as possible；(2) each bulk drug in medicine for oral administration of the present invention
Compatibility is proper, all medicines share, and energy is clearing heat and detoxicating, replenishes qi to invigorate the spleen, tonifies the liver and kidney, flat liver solution strongly fragrant, dispelling wind and removing obstruction in the meridians, expel endogenous wind to relieve convulsion, extensive
Multiple dermal melanin, and then the purpose treated both principal and secondary aspect of disease, are fundamentally solved because the disappearance of melanocyte causes topical skin tone
Bleach, the symptom such as itch, be finally reached the healing purpose to leucoderma, and it is uneasy to recur.
Embodiment
With reference to embodiment further make detailed elaboration to technical scheme, but the not all present invention in pairs
Scope limits.
Embodiment 1
A kind of medicine for oral administration for treating leucoderma, include the raw material of following parts by weight：10 parts of duckweed spirodela, 80 parts of tribulus terrestris,
15 parts of motherwort, 10 parts of the achene of Siberian cocklebur, 25 parts of Semen sesami nigrum, 25 parts of black fungus, 25 parts of the fruit of glossy privet, 10 parts of the root of Dahurain angelica, 15 parts of radix scrophulariae, light leaf
15 parts of Chinese prickly ash, 25 parts of kadsura longepedunculata, 15 parts of teasel, 25 parts of the fleece-flower root, 25 parts of gynostemma pentaphylla, 25 parts of Eclipta prostrata.
The preparation method of the medicine for oral administration of the treatment leucoderma, comprises the following steps：
By duckweed spirodela, tribulus terrestris, motherwort, the achene of Siberian cocklebur, the fruit of glossy privet, the root of Dahurain angelica, radix scrophulariae, zanthoxylum nitidum, kadsura longepedunculata,
Teasel, gynostemma pentaphylla, Eclipta prostrata add water to cook 1h, and amount of water is 4 times of above-mentioned each medicine gross mass, is then separated by filtration the dregs of a decoction
And decoction, it is 1.20 (60 DEG C) thick pastes to be concentrated under reduced pressure into relative density, vacuum drying, crushed 80 mesh sieves, obtains Chinese medicine water extraction
Fine powder；
(2) the step (1) gained dregs of a decoction are taken, the ethanol solution refluxing extraction 1 time for adding volumetric concentration to be 50%, time 1h, are added
The quality for entering 50% ethanol solution is 3 times of dregs of a decoction quality, is separated by filtration the dregs of a decoction and extract solution, extract solution is concentrated under reduced pressure into relative
Density is 1.20 (60 DEG C) thick pastes；
(3) the step (2) gained dregs of a decoction are taken, the ethanol solution refluxing extraction 1 time for adding volumetric concentration to be 90%, time 1h, are added
The quality for entering 90% ethanol solution is 3 times of dregs of a decoction quality, is separated by filtration the dregs of a decoction and extract solution, extract solution is concentrated under reduced pressure into relative
Density is 1.20 (60 DEG C) thick pastes；
(4) by step, (2) and (3) gained thick paste mixes, and vacuum drying, crushed 80 mesh sieves, obtains Chinese medicine alcohol extracting fine powder；
(5) Semen sesami nigrum, black fungus, the fleece-flower root are crushed to 150 mesh respectively, obtained black sesame powder, black fungus powder, He Shou
Black powder mixes with Chinese medicine water extraction fine powder, Chinese medicine alcohol extracting fine powder, produces fine-powdered medicine for oral administration.
Usage and dosage：1 hour after meal oral fine-powdered medicine for oral administration of morning and evening daily, each 6g.
Embodiment 2
A kind of medicine for oral administration for treating leucoderma, include the raw material of following parts by weight：Duckweed spirodela 10-20 parts, tribulus terrestris 120
Part, 25 parts of motherwort, 20 parts of the achene of Siberian cocklebur, 35 parts of Semen sesami nigrum, 35 parts of black fungus, 35 parts of the fruit of glossy privet, 20 parts of the root of Dahurain angelica, 25 parts of radix scrophulariae,
25 parts of zanthoxylum nitidum, 35 parts of kadsura longepedunculata, 25 parts of teasel, 35 parts of the fleece-flower root, 35 parts of gynostemma pentaphylla, 35 parts of Eclipta prostrata.
The preparation method of the medicine for oral administration of the treatment leucoderma, comprises the following steps：
By duckweed spirodela, tribulus terrestris, motherwort, the achene of Siberian cocklebur, the fruit of glossy privet, the root of Dahurain angelica, radix scrophulariae, zanthoxylum nitidum, kadsura longepedunculata,
Teasel, gynostemma pentaphylla, Eclipta prostrata add water to cook 2h, and amount of water is 6 times of above-mentioned each medicine gross mass, is then separated by filtration the dregs of a decoction
And decoction, it is 1.20 (60 DEG C) thick pastes to be concentrated under reduced pressure into relative density, vacuum drying, crushed 120 mesh sieves, obtains Chinese medicine water extraction
Fine powder；
(2) the step (1) gained dregs of a decoction are taken, the ethanol solution refluxing extraction 1 time for adding volumetric concentration to be 50%, time 2h, are added
The quality for entering 50% ethanol solution is 5 times of dregs of a decoction quality, is separated by filtration the dregs of a decoction and extract solution, extract solution is concentrated under reduced pressure into relative
Density is 1.20 (60 DEG C) thick pastes；
(3) the step (2) gained dregs of a decoction are taken, the ethanol solution refluxing extraction 1 time for adding volumetric concentration to be 90%, time 2h, are added
The quality for entering 90% ethanol solution is 5 times of dregs of a decoction quality, is separated by filtration the dregs of a decoction and extract solution, extract solution is concentrated under reduced pressure into relative
Density is 1.20 (60 DEG C) thick pastes；
(4) by step, (2) and (3) gained thick paste mixes, and vacuum drying, crushed 120 mesh sieves, obtains Chinese medicine alcohol extracting fine powder；
(5) Semen sesami nigrum, black fungus, the fleece-flower root are crushed to 200 mesh respectively, obtained black sesame powder, black fungus powder, He Shou
Black powder mixes with Chinese medicine water extraction fine powder, Chinese medicine alcohol extracting fine powder, produces fine-powdered medicine for oral administration.
Usage and dosage：1 hour after meal oral fine-powdered medicine for oral administration of morning and evening daily, each 4g.
Embodiment 3
A kind of medicine for oral administration for treating leucoderma, include the raw material of following parts by weight：15 parts of duckweed spirodela, 100 parts of tribulus terrestris,
20 parts of motherwort, 15 parts of the achene of Siberian cocklebur, 30 parts of Semen sesami nigrum, 30 parts of black fungus, 30 parts of the fruit of glossy privet, 15 parts of the root of Dahurain angelica, 20 parts of radix scrophulariae, light leaf
20 parts of Chinese prickly ash, 30 parts of kadsura longepedunculata, 20 parts of teasel, 30 parts of the fleece-flower root, 30 parts of gynostemma pentaphylla, 30 parts of Eclipta prostrata.
The preparation method of the medicine for oral administration of the treatment leucoderma, comprises the following steps：
By duckweed spirodela, tribulus terrestris, motherwort, the achene of Siberian cocklebur, the fruit of glossy privet, the root of Dahurain angelica, radix scrophulariae, zanthoxylum nitidum, kadsura longepedunculata,
Teasel, gynostemma pentaphylla, Eclipta prostrata add water to cook 1.5h, and amount of water is 5 times of above-mentioned each medicine gross mass, is then separated by filtration medicine
Slag and decoction, it is 1.20 (60 DEG C) thick pastes to be concentrated under reduced pressure into relative density, vacuum drying, crushed 100 mesh sieves, obtains middle liquid medicine
Carry fine powder；
(2) the step (1) gained dregs of a decoction are taken, add the ethanol solution refluxing extraction 1 time, time 1.5h that volumetric concentration is 50%,
The quality for adding 50% ethanol solution is 4 times of dregs of a decoction quality, is separated by filtration the dregs of a decoction and extract solution, extract solution is concentrated under reduced pressure into phase
It is 1.20 (60 DEG C) thick pastes to density；
(3) the step (2) gained dregs of a decoction are taken, add the ethanol solution refluxing extraction 1 time, time 1.5h that volumetric concentration is 90%,
The quality for adding 90% ethanol solution is 4 times of dregs of a decoction quality, is separated by filtration the dregs of a decoction and extract solution, extract solution is concentrated under reduced pressure into phase
It is 1.20 (60 DEG C) thick pastes to density；
(4) by step, (2) and (3) gained thick paste mixes, and vacuum drying, crushed 100 mesh sieves, obtains Chinese medicine alcohol extracting fine powder；
(5) Semen sesami nigrum, black fungus, the fleece-flower root are crushed to 200 mesh respectively, obtained black sesame powder, black fungus powder, He Shou
Black powder mixes with Chinese medicine water extraction fine powder, Chinese medicine alcohol extracting fine powder, produces fine-powdered medicine for oral administration.
Usage and dosage：1 hour after meal oral fine-powdered medicine for oral administration of morning and evening daily, each 5g.
General information
1st, clinical data
In order to preferably investigate the clinical efficacy and safety of the oral medicinal herb medicine of the present invention, clinical observation treatment 60
Patient.
2nd, diagnostic method
Reference《Skin nursing》The diagnostic criteria of middle leucoderma is diagnosed.
3rd, treatment method
1 hour after meal oral fine-powdered medicine for oral administration, each 5g, treatment time are 3 months sooner or later daily.
4th, criterion of therapeutical effect；
Cure：The colour of skin is dimmed, no scratchiness, and affected part hair is normal；
It is effective：The colour of skin is dimmed, there is scratchiness once in a while, and affected part hair is normal；
Effectively：The colour of skin is dimmed, also often there is scratchiness, and affected part hair turns white；
It is invalid：Colour of skin milky, with scratchiness, affected part hair turns white；
5th, treatment results
| Cure | It is effective | Effectively | It is invalid | It is total effective | |
| Number (example) | 56 | 2 | 2 | 0 | 60 |
| Statistics rate (%) | 93.3 | 3.3 | 3.3 | 0 | 100 |
6th, conclusion
Treatment results show that the cure rate of oral medicinal herb medicine of the invention is high, and therapeutic effect is notable, can treat both principal and secondary aspect of disease, make
The regeneration of human body melanin recovers normal, fundamentally cures leucoderma.
Claims (3)
1. a kind of medicine for oral administration for treating leucoderma, it is characterised in that include the raw material of following parts by weight：Duckweed spirodela 10-20 parts,
Tribulus terrestris 80-120 parts, motherwort 15-25 parts, achene of Siberian cocklebur 10-20 parts, Semen sesami nigrum 25-35 parts, black fungus 25-35 parts, the fruit of glossy privet
25-35 parts, root of Dahurain angelica 10-20 parts, radix scrophulariae 15-25 parts, zanthoxylum nitidum 15-25 parts, kadsura longepedunculata 25-35 parts, teasel 15-25
Part, fleece-flower root 25-35 parts, gynostemma pentaphylla 25-35 parts, Eclipta prostrata 25-35 parts.
2. the medicine for oral administration of leucoderma is treated according to claim 1, it is characterised in that include the raw material of following parts by weight：It is purple
Carry on the back 15 parts of duckweed, 100 parts of tribulus terrestris, 20 parts of motherwort, 15 parts of the achene of Siberian cocklebur, 30 parts of Semen sesami nigrum, 30 parts of black fungus, the fruit of glossy privet 30
Part, 15 parts of the root of Dahurain angelica, 20 parts of radix scrophulariae, 20 parts of zanthoxylum nitidum, 30 parts of kadsura longepedunculata, 20 parts of teasel, 30 parts of the fleece-flower root, gynostemma pentaphylla
30 parts, 30 parts of Eclipta prostrata.
3. a kind of preparation method of the medicine for oral administration of the leucoderma for the treatment of as claimed in claim 1, it is characterised in that including following step
Suddenly：
(1) by duckweed spirodela, tribulus terrestris, motherwort, the achene of Siberian cocklebur, the fruit of glossy privet, the root of Dahurain angelica, radix scrophulariae, zanthoxylum nitidum, kadsura longepedunculata, dipsacus root
Continuous, gynostemma pentaphylla, Eclipta prostrata add water to cook 1-2h, and amount of water is 4-6 times of above-mentioned each medicine gross mass, is then separated by filtration the dregs of a decoction
And decoction, it is 1.20 (60 DEG C) thick pastes to be concentrated under reduced pressure into relative density, vacuum drying, crushed 80-120 mesh sieves, obtains Chinese medicine
Water extraction fine powder；
(2) the step (1) gained dregs of a decoction are taken, adds the ethanol solution refluxing extraction 1 time, time 1-2h that volumetric concentration is 50%, adds
The quality of 50% ethanol solution is 3-5 times of dregs of a decoction quality, is separated by filtration the dregs of a decoction and extract solution, extract solution is concentrated under reduced pressure into relative
Density is 1.20 (60 DEG C) thick pastes；
(3) the step (2) gained dregs of a decoction are taken, adds the ethanol solution refluxing extraction 1 time, time 1-2h that volumetric concentration is 90%, adds
The quality of 90% ethanol solution is 3-5 times of dregs of a decoction quality, is separated by filtration the dregs of a decoction and extract solution, extract solution is concentrated under reduced pressure into relative
Density is 1.20 (60 DEG C) thick pastes；
(4) by step, (2) and (3) gained thick paste mixes, and vacuum drying, crushed 80-120 mesh sieves, obtains Chinese medicine alcohol extracting fine powder；
(5) Semen sesami nigrum, black fungus, the fleece-flower root are crushed to 150-200 mesh respectively, obtained black sesame powder, black fungus powder, He Shou
Black powder mixes with Chinese medicine water extraction fine powder, Chinese medicine alcohol extracting fine powder, produces fine-powdered medicine for oral administration.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102949539A (en) * | 2012-11-14 | 2013-03-06 | 西安福安创意咨询有限责任公司 | Pure traditional Chinese medicine health care product granule used for treating vitiligo and preparation method thereof |
| CN103977107A (en) * | 2014-05-22 | 2014-08-13 | 刘增艳 | Traditional Chinese medicine composition for treating leucoderma |
-
2017
- 2017-07-07 CN CN201710549352.6A patent/CN107334881A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102949539A (en) * | 2012-11-14 | 2013-03-06 | 西安福安创意咨询有限责任公司 | Pure traditional Chinese medicine health care product granule used for treating vitiligo and preparation method thereof |
| CN103977107A (en) * | 2014-05-22 | 2014-08-13 | 刘增艳 | Traditional Chinese medicine composition for treating leucoderma |
Non-Patent Citations (1)
| Title |
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| 闫铁夫等: "《皮肤病临床诊疗与皮肤美容整形》", 30 June 2017, 吉林科学技术出版社 * |
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Application publication date: 20171110 |