CN102949539A - Pure traditional Chinese medicine health care product granule used for treating vitiligo and preparation method thereof - Google Patents
Pure traditional Chinese medicine health care product granule used for treating vitiligo and preparation method thereof Download PDFInfo
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- CN102949539A CN102949539A CN 201210454968 CN201210454968A CN102949539A CN 102949539 A CN102949539 A CN 102949539A CN 201210454968 CN201210454968 CN 201210454968 CN 201210454968 A CN201210454968 A CN 201210454968A CN 102949539 A CN102949539 A CN 102949539A
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Abstract
The invention discloses a pure traditional Chinese medicine health care product granule used for treating vitiligo and a preparation method thereof. The pure traditional Chinese medicine health care product granule comprises following raw material medicine ingredients in parts by weight: 15 parts of prepared rehmannia roots, 15 parts of radix polygoni multiflori, 15 parts of semen astragali complanati, 10 parts of fructus psoraleae, 10 parts of eclipta alba, 10 parts of wolfberry fruit, 15 parts of tribulus terrestris, 10 parts of duckweed, 10 parts of cocklebur fruit, 10 parts of Chinese angelica, 10 parts of ligusticum wallichii, 10 parts of radix angelicae, 6 parts of liquorice and 15 parts of siegesbeckia orientalis. According to the pure traditional Chinese medicine health care product granule used for curing the vitiligo and the preparation method thereof, the granule disclosed by the invention is prepared according to a compatible regulation for a traditional Chinese medicine prescription, can comprehensively adjust the equilibrium between Yin and Yang through benefiting qi, nourishing the blood, relaxing tendons and dredging collaterals, so an immune function is enhanced and the aims of unblocked body blood circulation and damaged skin vitiligo repairing are achieved. Compared with existing pills and capsules achieving related effects, the pure traditional Chinese medicine health care product granule has the advantages of low dose, good taste, convenience in taking, faster absorption, high bioavailability, stable quality, simple production process and the like.
Description
Technical field
The invention belongs to the health care medicine technical field, particularly a kind of leukodermic pure Chinese medicine health care product granule and preparation method thereof that is used for the treatment of.
Background technology
Vitiligo is upper kind unusual common skin diseases of metabolism of pigment, and without obvious inducement, doctor trained in Western medicine is thought may be relevant with heredity, autoimmune, endocrine and the factors such as spiritual.Because etiology unknown, treatment is also without desirable way.Chinese medicine to the understanding of primary disease very early, the record of existing treatment in " 52 Bingfang " " white place ", and second prescription is arranged." General Treatise on the Cause and Symptoms of Diseases " in Tang of Sui epoch, Prescriptions Worth Thousand Gold for Emergencies begin to claim " leucoderma ", " vitiligo " or " white lump ", and point out that its pathogenesis is " ailment said due to cold or exposure is won in skin, the vim and vigour discord ".On method for the treatment of, then to dispel the wind as main.The name that also has " vitiligo " in rear physicians from a family for generations family and the doctor's nationality observes, describes more detailed to primary disease, " Shi Zhiyi morning " (Golden Mirror of Medicine) roughly from wind, wet, hot several aspects staff, advocated in treatment.
Modern Chinese medicine starts from the beginning of the fifties to treating leukodermic clinical report.But 50～sixties, interrelated data was few, and mostly was case.To the seventies, the report amount has increased slightly, and content is also more thoroughgoing and painstaking than before, mostly is the concentrated observation of multiple-case, even the large sample case document of thousands of examples is arranged.Therapeutic Method is more with folk prescription or Chinese traditional compound medicine; Such as psoralea tincture, wild Fructus Foeniculi injection, the sub-ball of Fructus Atriplicis Sibiricae, Methoxypsoralen (being Fructus Psoraleae extract), Coumarins Chinese medicine leaching liquid etc., and the Comprehensive Treatment later stage seventies often, understanding on etiology and pathogenesis and method for the treatment of is not limited to forefathers' old saying, by clinical observation, find that qi depression to blood stasis and deficiency of the liver and kindey are two large main pathogenesis of primary disease, use blood circulation promoting and blood stasis dispelling and nourishing the liver and kidney treatment primary disease, greatly improved clinical efficacy, for providing new thinking, the Chinese traditional treatment primary disease suddenly increases with the leukodermic Document Quantity of relevant Chinese medicine of the 980's of method, be about front 30 years 4 times, Therapeutic Method is also varied, except Chinese medicine takes orally, outside putting on the skin outward, also have many acupuncture contents, such as body acupuncture, ear acupuncture, herbs-partition moxibustion, moxa roll is smoked moxibustion, acupoint burying etc.In addition, the report that also has the aspects such as a small amount of qigong, massage, dietetic therapy.Till the end of the year 1991, the document of having reported adds up to 102 pieces, nearly 9,000 examples of case sum of accumulation, and generally about 90%, if the short type that the distributes patient of the course of disease, then effective percentage can be higher for effective percentage.At present, a large amount of work has been done in the various places leukodermic research of traditional Chinese medical science bound pair, and treatment trends towards comprising the composite treatment of oral medicinal herb, external, sun exposure, acupuncture and Western medicine etc. gradually.In addition, consider the easy wound of being exposed to the sun of primary disease, so advocate to be expert at the appropriate to the occasion burning sun of avoiding of sun tan.
Although obtained some experiences with the Chinese medicine vitiligo, also existed the problem that cure rate is low and the course for the treatment of is long at present.Mechanism research is carried out not yet well, and pharmacological research is heavy single medicinal material mainly, and is then less to the research of compound recipe.The present invention carries out comprehensively deep research from these several respects, further improves cure rate, Shorten the Treatment Process.
Summary of the invention
Purpose of the present invention aims to provide a kind of leukodermic pure Chinese medicine health care product granule and preparation method thereof that is used for the treatment of, by benefiting QI and nourishing blood, and channels sootheing and network vessel quickening, comprehensive balance the body equilibrium between yin and yang, strengthen immunologic function, it is unimpeded to reach the health blood circulation, repairs the purpose of impaired leukoderma.Its taking dose is little, mouthfeel good, taking convenience, absorption is very fast, bioavailability is high, steady quality, production technology are simple.
Technical scheme of the present invention is: design a kind of leukodermic pure Chinese medicine health care product granule that is used for the treatment of, it is characterized in that crude drug composition and weight proportion thereof that it contains are: thermally 15 parts, 15 parts of the Radixs Polygoni Multiflori, 15 parts of Semen Astragali Complanatis, 10 parts of Fructus Psoraleaes, 10 parts of Herba Ecliptaes, 10 parts of Fructus Lycii, 15 parts of Fructus Atriplicis Sibiricaees, 10 parts in Herba Spirodelae, 10 parts of Fructus Xanthii, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiongs, 10 parts of the Radixs Angelicae Dahuricae, 6 parts in Radix Glycyrrhizae, 15 parts of Herba Siegesbeckiae.
It may further comprise the steps described a kind of preparation method that is used for the treatment of leukodermic pure Chinese medicine health care product granule:
1) by following weight ratio weighting raw materials: thermally 15 parts, 15 parts of the Radixs Polygoni Multiflori, 15 parts of Semen Astragali Complanatis, 10 parts of Fructus Psoraleaes, 10 parts of Herba Ecliptaes, 10 parts of Fructus Lycii, 15 parts of Fructus Atriplicis Sibiricaees, 10 parts in Herba Spirodelae, 10 parts of Fructus Xanthii, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiongs, 10 parts of the Radixs Angelicae Dahuricae, 6 parts in Radix Glycyrrhizae, 15 parts of Herba Siegesbeckiae;
2) above 14 flavors decoct with water secondary, and 2 hours for the first time, 1.5 hours for the second time, gradation filtered, and merging filtrate dusts with spray dryer, and is for subsequent use;
3) dry powder described in the step 2 is added starch, anhydrous glucose, stevioside, mix homogeneously;
4) said mixture is added 80% ethanol soft material processed;
5) granulate arrangement with soft material 14 mesh sieves;
6) packing, warehouse-in get final product.
Advantage of the present invention is: according to traditional Chinese medical science tradition prescription method in conjunction with the theoretical prescription of modern Chinese medicine, by benefiting QI and nourishing blood, channels sootheing and network vessel quickening, comprehensive balance the body equilibrium between yin and yang, strengthen immunologic function, it is unimpeded to reach the health blood circulation, repairs the purpose of impaired leukoderma.Wherein in the prescription monarch drug thermally matter moisten into kidney, kind nourishing kidney yin, life essence-filling, marrow-benefitting is the key medicine of tonifying kidney-yin.Ancients call it " large tonifying five ZANG-organs is Kidney-Yin ", " mending greatly true water ".Normal be equal to usefulness with Rhizoma Dioscoreae, Fructus Corni, treat the hepatic and renal YIN deficiency, soreness of the waist and knees, seminal emission, night sweat, tinnitus, deafness and quench one's thirst etc., but invigorating the liver and kidney, beneficial marrow.Radix Polygoni Multiflori invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening are used for blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, chronic malaria body void etc.Semen Astragali Complanati temperature compensation Liver and kidney, controlling nocturnal emission with astringent drugs, reducing urination makes eye bright.Be used for lumbago due to renal deficiency, seminal emission premature ejaculation, nebulousurine leukorrhagia, dribbling urination, dizzy blurred vision.Fructus Atriplicis Sibiricae suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.Be used for the dizziness due to hyperactivity of liver-YANG headache, hypochondriac pain due to stagnation of liverQI, headache due to pathogenic wind-heat, conjunctival congestion and swelling pain, the diseases such as skin pruritus.Herba Siegesbeckiae rheumatism, the meridian dredging, detoxifcation.Be used for rheumatic arthralgia, bones and muscles pain, weakness of the waist and knees, carbuncle pyogenic infections from tumour or sore, rubella eczema, hypertension.Embodiment of the invention taking dose is little, mouthfeel good, taking convenience absorb very fast, bioavailability is high, steady quality, production technology are simple.
The specific embodiment
The invention will be further described below in conjunction with specific embodiment, but not as limitation of the present invention.The part that is not described in detail in the present embodiment is to adopt prior art, and industry standard or known approaches.
Embodiment 1
Be used for the treatment of leukodermic pure Chinese medicine health care product granule preparation method it may further comprise the steps:
1) by following weight ratio weighting raw materials: thermally 15 parts, 15 parts of the Radixs Polygoni Multiflori, 15 parts of Semen Astragali Complanatis, 10 parts of Fructus Psoraleaes, 10 parts of Herba Ecliptaes, 10 parts of Fructus Lycii, 15 parts of Fructus Atriplicis Sibiricaees, 10 parts in Herba Spirodelae, 10 parts of Fructus Xanthii, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiongs, 10 parts of the Radixs Angelicae Dahuricae, 6 parts in Radix Glycyrrhizae, 15 parts of Herba Siegesbeckiae;
2) above 14 flavors decoct with water secondary, and 2 hours for the first time, 1.5 hours for the second time, gradation filtered, and merging filtrate dusts with spray dryer, and is for subsequent use;
3) dry powder described in the step 2 is added starch, anhydrous glucose, stevioside, mix homogeneously;
4) said mixture is added 80% ethanol soft material processed;
5) granulate arrangement with soft material 14 mesh sieves;
6) packing, warehouse-in get final product.
To be that the embodiment of the invention is a kind of be used for the treatment of leukodermic pure Chinese medicine health care product granule and be used for the treatment of leukodermic clinical observation the below:
1 data and method
1.1 physical data
Select patients with vitiligo 120 examples receive treatment voluntarily, the men and women does not limit, the course of disease 2 thoughtful 30 years, average 4.68 years.Be divided at random treatment group 1, treatment group 2, treatment group 3, matched group, every group of 30 examples; Each is organized the patient age symptom and consists of without significant difference.Has comparability (P〉0.05).
1.2 Therapeutic Method
The treatment group Primary Care is consistent, and matched group is not taken medicine.The treatment group 1 usefulness embodiment of the invention 1, every day three times, one time 2,30 is a course for the treatment of.Every 6～the 9g that takes for the treatment of group 2 usefulness compound kalizirandings (the Xinjiang New Times, Pharmaceutical Co produced), 2 times on the one; Treatment group 3 usefulness are driven Bai Babu phase sheet, Xinjiang Hua Kang Pharmaceutical, one time 5,3 times on the one.
2 results
2.1 curative effect determinate standard
Criterion of therapeutical effect (draft) according to national pigment disease group formulation: recovery from illness: white macula all disappears, and recovers the normal colour of skin; Produce effects: white macula partly disappears or dwindles, the area that recovers the normal colour of skin account for the skin lesion area more than; Effectively: white macula partly disappears or dwindles, the area that recovers the normal colour of skin account for the skin lesion area more than, but in; Invalid: white macula is unchanged or dwindle, the area that recovers the normal colour of skin account for the skin lesion area 10% in.
2.2 therapeutic outcome
| Cure | Produce effects | Effectively | Invalid | Effective percentage | |
| Contrast | 30 | 0 | |||
| Treatment group 1 | 15 | 6 | 7 | 2 | 93% |
| Treatment group 2 | 12 | 7 | 7 | 4 | 87% |
| Treatment group 3 | 9 | 13 | 3 | 5 | 83% |
3 discuss
Chinese medicine thinks that vitiligo is divided into two types, the one, and the hepatic and renal YIN deficiency and cause qi-blood disharmony, qi stagnation blood stasis, this kind of is relevant with the so-called autoimmune of modern medicine, and another type is disarmony between the heart and kidney, deficiency of both the heart and spleen and cause qi-blood disharmony, qi stagnation blood stasis.Adopt Chinese medicine to import administration, improve the local microcirculation obstacle, improve the photosensitization of skin, local trace element supplement strengthens tyrosinase activity, promotes the synthetic of the black pigment of skin, reaches the healing purpose.And then illustrate that embodiment 1 affiliated prescription is reliably effective in this invention.
Claims (2)
1. one kind is used for the treatment of leukodermic pure Chinese medicine health care product granule, it is characterized in that crude drug composition and weight proportion thereof that it contains are: thermally 15 parts, 15 parts of the Radixs Polygoni Multiflori, 15 parts of Semen Astragali Complanatis, 10 parts of Fructus Psoraleaes, 10 parts of Herba Ecliptaes, 10 parts of Fructus Lycii, 15 parts of Fructus Atriplicis Sibiricaees, 10 parts in Herba Spirodelae, 10 parts of Fructus Xanthii, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiongs, 10 parts of the Radixs Angelicae Dahuricae, 6 parts in Radix Glycyrrhizae, 15 parts of Herba Siegesbeckiae.
A kind of preparation method that is used for the treatment of leukodermic pure Chinese medicine health care product granule according to claim 1 it may further comprise the steps:
1) by following weight ratio weighting raw materials: thermally 15 parts, 15 parts of the Radixs Polygoni Multiflori, 15 parts of Semen Astragali Complanatis, 10 parts of Fructus Psoraleaes, 10 parts of Herba Ecliptaes, 10 parts of Fructus Lycii, 15 parts of Fructus Atriplicis Sibiricaees, 10 parts in Herba Spirodelae, 10 parts of Fructus Xanthii, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiongs, 10 parts of the Radixs Angelicae Dahuricae, 6 parts in Radix Glycyrrhizae, 15 parts of Herba Siegesbeckiae;
2) above 14 flavors decoct with water secondary, and 2 hours for the first time, 1.5 hours for the second time, gradation filtered, and merging filtrate dusts with spray dryer, and is for subsequent use;
3) dry powder described in the step 2 is added starch, anhydrous glucose, stevioside, mix homogeneously;
4) said mixture is added 80% ethanol soft material processed;
5) granulate arrangement with soft material 14 mesh sieves;
6) packing, warehouse-in get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210454968 CN102949539A (en) | 2012-11-14 | 2012-11-14 | Pure traditional Chinese medicine health care product granule used for treating vitiligo and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201210454968 CN102949539A (en) | 2012-11-14 | 2012-11-14 | Pure traditional Chinese medicine health care product granule used for treating vitiligo and preparation method thereof |
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| CN102949539A true CN102949539A (en) | 2013-03-06 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104189682A (en) * | 2014-09-19 | 2014-12-10 | 葛文涛 | Chinese medicinal preparation for treating leucoderma |
| CN107334881A (en) * | 2017-07-07 | 2017-11-10 | 王浩绪 | A kind of medicine for oral administration for treating leucoderma and preparation method thereof |
-
2012
- 2012-11-14 CN CN 201210454968 patent/CN102949539A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104189682A (en) * | 2014-09-19 | 2014-12-10 | 葛文涛 | Chinese medicinal preparation for treating leucoderma |
| CN107334881A (en) * | 2017-07-07 | 2017-11-10 | 王浩绪 | A kind of medicine for oral administration for treating leucoderma and preparation method thereof |
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Application publication date: 20130306 |