CN108261506B - Medicine for treating alopecia - Google Patents

Medicine for treating alopecia Download PDF

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CN108261506B
CN108261506B CN201810115982.7A CN201810115982A CN108261506B CN 108261506 B CN108261506 B CN 108261506B CN 201810115982 A CN201810115982 A CN 201810115982A CN 108261506 B CN108261506 B CN 108261506B
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medicine
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alopecia
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CN108261506A (en
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冯丽华
冯拂明
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Beijing Huaxia Kangtai Medical Research Institute
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Abstract

The invention discloses a medicine for treating alopecia, which comprises an oral medicine and an external medicine, wherein the oral medicine comprises the following traditional Chinese medicine raw materials in parts by weight: carapax et Plastrum Testudinis, carapax Trionycis, radix Polygoni Multiflori Preparata, radix rehmanniae Preparata, fructus Lycii, Corni fructus, fructus Ligustri Lucidi, radix Angelicae sinensis, Mori fructus, rhizoma Gastrodiae, semen Cuscutae, Ecliptae herba, rhizoma Cyperi, cortex Dictamni Radicis, Notopterygii rhizoma, radix Paeoniae Rubra, rhizoma Drynariae, Rubi fructus, Saviae Miltiorrhizae radix, semen Ziziphi Spinosae, bupleuri radix, herba Artemisiae Scopariae, folium Platycladi, folium Mori, herba asari, radix Codonopsis Pilosulae, and Scolopendra. The medicine for treating alopecia is used together with oral medicines and external medicines, the oral medicines are compatible and formulated according to a certain proportion, and the components are mutually cooperated, so that the medicine has the effects of invigorating kidney, growing hair, nourishing blood, resolving stagnation, removing fat, activating blood, clearing heat and cooling blood, achieves the purpose of treating both symptoms and root causes of alopecia, and has a good treatment effect on seborrheic alopecia, alopecia areata and alopecia totalis. The traditional Chinese medicine in the technical scheme adopts natural traditional Chinese medicine raw materials, hardly generates any toxic or side effect, and is safe and reliable.

Description

Medicine for treating alopecia
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a medicine for treating alopecia.
Background
Alopecia is the phenomenon of hair loss, and is divided into physiological and pathological. Physiological alopecia refers to normal shedding of hair; pathologic hair loss refers to abnormal or excessive hair loss. Common alopecia includes alopecia areata, seborrheic alopecia, etc., the former is also called round alopecia, the folk name is 'ghost shaving head', the round or oval 'alopecia areata' appears on the head of a patient suddenly, no subjective symptom exists, hair loss at an affected part is observed by naked eyes, and no skin abnormality exists; the latter scalp is greasy and shiny with a large amount of dandruff, is in the form of gray chaff, has dry hair, lack of luster, feeling of itching, and begins to be symmetrical to lose hair on both sides of the forehead and the top of the head, gradually becomes thin and thin, and the hair follicle shrinks, resulting in permanent regeneration failure. Regardless of male and female, whether the hair loss is of any type or a large amount of hair loss is very annoying.
The life rhythm of the modern society is accelerated day by day, the work and the mental pressure of people are increased day by day, and the conditions of nutrition imbalance and excessive overdraft of the body needed by hair are increased more and more due to overuse of the brain and over-mental stress. According to statistics of relevant data, the morbidity of the alopecia in China is as high as 20-24%, and while the number of the alopecia and the morbidity of people in China is increased year by year, the number of the morbidity people is also young. At present, the means for treating alopecia are various, but a plurality of drug treatments have a plurality of side effects, even the drugs contain a plurality of harmful trace elements, which seriously affect the health of people; some medicines are used for treatment, and the problems of temporary solution, non-primary treatment and poor curative effect exist.
Disclosure of Invention
The invention aims to overcome the technical defects, provides a medicine for treating alopecia and solves the technical problems of poor curative effect and toxic and side effects of the medicine for treating alopecia in the prior art.
In order to achieve the technical purpose, the technical scheme of the invention provides a medicine for treating alopecia, which comprises an oral medicine and an external medicine, wherein the oral medicine comprises the following traditional Chinese medicine raw materials in parts by weight: 40-400 parts of tortoise plastron, 40-400 parts of turtle shell, 40-400 parts of prepared fleece-flower root, 30-300 parts of radix rehmanniae, 30-300 parts of prepared rehmannia root, 30-300 parts of medlar, 30-300 parts of cornus officinalis, 30-300 parts of glossy privet fruit, 30-300 parts of angelica, 30-300 parts of mulberry, 30-300 parts of rhizoma gastrodiae, 26-260 parts of semen cuscutae, 26-260 parts of eclipta alba, 26-260 parts of rhizoma cyperi, 26-260 parts of cortex dictamni, 26-260 parts of notopterygium root, 26-260 parts of red paeony root, 26-260 parts of rhizoma drynariae, 26-260 parts of raspberry, 26-260 parts of salvia miltiorrhiza, 26-260 parts of spina date seed, 20-200 parts of radix bupleuri, 20-200 parts of oriental wormwood, 20-200 parts of cacumen biotae, 20-200 parts of winter mulberry leaf, 15-150 parts of asarum, 10.
Compared with the prior art, the invention has the beneficial effects that: according to the technical scheme, the medicine for treating alopecia is prepared by carefully selecting traditional Chinese medicine components under the guidance of the traditional Chinese medicine theory and clinical experience and optimizing the proportion of the medicinal materials. The medicine for treating alopecia is used together with oral medicines and external medicines, the oral medicines are compatible and formulated according to a certain proportion, and the components are mutually cooperated, so that the medicine has the effects of invigorating kidney, growing hair, nourishing blood, resolving stagnation, removing fat, activating blood, clearing heat and cooling blood, achieves the purpose of treating both symptoms and root causes of alopecia, and has a good treatment effect on seborrheic alopecia, alopecia areata and alopecia totalis. The traditional Chinese medicine in the technical scheme adopts natural traditional Chinese medicine raw materials, hardly generates any toxic or side effect, and is safe and reliable.
Detailed Description
The embodiment provides a medicine for treating alopecia, which comprises an oral medicine and an external medicine, wherein the oral medicine comprises the following traditional Chinese medicine raw materials in parts by weight: 40-400 parts of tortoise plastron, 40-400 parts of turtle shell, 40-400 parts of prepared fleece-flower root, 30-300 parts of radix rehmanniae, 30-300 parts of prepared rehmannia root, 30-300 parts of medlar, 30-300 parts of cornus officinalis, 30-300 parts of glossy privet fruit, 30-300 parts of angelica, 30-300 parts of mulberry, 30-300 parts of rhizoma gastrodiae, 26-260 parts of semen cuscutae, 26-260 parts of eclipta alba, 26-260 parts of rhizoma cyperi, 26-260 parts of cortex dictamni, 26-260 parts of notopterygium root, 26-260 parts of red paeony root, 26-260 parts of rhizoma drynariae, 26-260 parts of raspberry, 26-260 parts of salvia miltiorrhiza, 26-260 parts of spina date seed, 20-200 parts of radix bupleuri, 20-200 parts of oriental wormwood, 20-200 parts of cacumen biotae, 20-200 parts of winter mulberry leaf, 15-150 parts of asarum, 10.
Tortoise plastron: cold, sweet and salty in flavor, enter liver, kidney and heart meridians. Has the functions of nourishing yin, suppressing yang, tonifying kidney, strengthening bone, nourishing blood, tonifying heart, strengthening channel and stopping metrorrhagia. Can be used for treating hectic fever due to yin deficiency, hectic fever, night sweat, dizziness, internal stirring of deficient wind, flaccidity of bones and muscles, heart deficiency, amnesia, metrorrhagia, and menorrhagia.
Turtle shell: cold in nature and salty in taste, it enters liver and kidney meridians. Has the effects of nourishing yin, clearing heat, calming liver, calming wind, softening hardness and dissipating stagnation. For wind-heat syndrome due to internal heat and yin deficiency, manifested as wind-invasion of the lung, malaria, buoyi, amenorrhea and metrorrhagia, infantile convulsions and epilepsy.
Radix polygoni multiflori preparata: slightly warm in nature, bitter, sweet and astringent in flavor, and entering liver, heart and kidney meridians. Has effects in nourishing liver and kidney, replenishing essence and blood, nourishing heart, and tranquilizing mind. Can be used for treating soreness of waist and knees, dizziness, dim eyesight, palpitation, insomnia, and premature gray hair due to deficiency of liver and kidney and deficiency of essence and blood.
Dried rehmannia root: it is cold in nature, sweet and bitter in flavor, and enters heart, liver and kidney meridians. Has the functions of clearing away heat, cooling blood and promoting the production of body fluid. Can be used for treating warm diseases with yin impairment, fever with polydipsia, crimson tongue, coma, macula, hematemesis, epistaxis, consumptive disease with steaming bone, hemoptysis, diabetes, constipation, and metrorrhagia.
Prepared rehmannia root: it is warm in nature and sweet in taste, entering liver and kidney meridians. Has the functions of nourishing yin and enriching blood. It is indicated for deficiency of yin and blood, atrophy and weakness of waist and knees, fatigue, cough, steaming bone, seminal emission, metrorrhagia, menoxenia, diabetes, scanty urine, deafness and blurred vision.
Medlar: neutral in nature and sweet in flavor, it enters liver and kidney meridians. Has the effects of nourishing liver and kidney, replenishing vital essence and improving eyesight. Can be used for treating asthenia, soreness of waist and knees, vertigo, tinnitus, internal heat, diabetes, blood deficiency, sallow complexion, and blurred vision.
Cornus officinalis: it is warm in nature, sour and astringent in taste, and enters liver and kidney meridians. Has the efficacies of tonifying liver and kidney, and arresting seminal emission and relieving depletion. Can be used for treating vertigo, tinnitus, soreness of waist and knees, sexual impotence, spermatorrhea, enuresis, frequent micturition, metrorrhagia, leukorrhagia, sweating, asthenia, internal heat, and diabetes.
Glossy privet fruit: cold in nature, sweet and bitter in flavor, entering liver and kidney meridians. Has the effects of nourishing liver and kidney, improving eyesight and blackening hair. Can be used for treating vertigo, tinnitus, soreness of waist and knees, premature gray hair, and dim eyesight.
Chinese angelica: it is warm in nature, pungent and sweet in flavor, and enters liver, heart and spleen meridians. Has the functions of enriching blood, promoting blood circulation, regulating menstruation, relieving pain, moistening intestine and relaxing bowels. Can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, constipation due to intestinal dryness, rheumatic arthralgia, traumatic injury, superficial infection, pyocutaneous disease. The wine-soaked Chinese angelica can activate blood and dredge channels, and is used for treating amenorrhea and dysmenorrhea, rheumatic arthralgia and traumatic injury.
Mulberry: cold in nature, sweet and sour in flavor, entering heart, liver and kidney meridians. Has the functions of enriching blood, nourishing yin, promoting the production of body fluid and moistening dryness. Can be used for treating vertigo, tinnitus, palpitation, insomnia, premature gray hair, thirst due to body fluid consumption, internal heat, diabetes, and constipation due to blood deficiency. Tonify blood, nourish yin, promote the production of body fluid and moisten dryness. Can be used for treating vertigo, tinnitus, palpitation, insomnia, premature gray hair, thirst due to body fluid consumption, internal heat, diabetes, and constipation due to blood deficiency.
Gastrodia elata: neutral in nature and sweet in flavor, it enters liver meridian. Has the effects of calming endogenous wind and arresting convulsion. It can be used for treating vertigo, black eye, headache, numbness of limbs, hemiplegia, slurred speech, and infantile convulsion.
Dodder seed: it is warm in nature and sweet in flavor, and enters liver, kidney and spleen meridians. Has the effects of nourishing liver and kidney, securing essence, reducing urination, preventing miscarriage, improving eyesight and stopping diarrhea. Can be used for treating sexual impotence, spermatorrhea, enuresis, frequent micturition, soreness of waist and knees, blurred vision, tinnitus, fetal leakage due to kidney deficiency, threatened abortion, and spleen and kidney deficiency; externally treat vitiligo.
Eclipta alba: cold in nature, sweet and sour in flavor, entering liver and kidney meridians. Has the effects of tonifying liver and kidney, cooling blood and stopping bleeding. It can be used for treating hematemesis, hemoptysis, epistaxis, hematuria, hematochezia, dysentery, hemorrhage due to knife wound, premature gray hair, diphtheria, stranguria with turbid urine, leukorrhagia, and pudendal pruritus.
Rhizoma cyperi: mild in nature, pungent, sweet and bitter in flavor. It enters liver, spleen and triple energizer meridians. Has the effects of regulating qi, resolving stagnation, relieving pain and regulating menstruation. It is indicated for disharmony of liver and stomach, qi stagnation, distending pain in chest, abdomen and hypochondrium, phlegm and fluid retention, irregular menstruation, metrorrhagia, metrostaxis and leukorrhagia.
Cortex dictamni: it is cold in nature, bitter and salty in taste, and enters spleen, lung, small intestine, stomach and bladder meridians. Has the effects of dispelling pathogenic wind, eliminating dampness, clearing heat and detoxicating. It is used to treat sore due to wind-heat, scabies, tinea, prurigo, rheumatic arthralgia, and jaundice.
Notopterygium root: it is warm in nature, pungent and bitter in flavor, entering bladder and kidney meridians. Has the effects of dispelling exterior cold, dispelling wind-damp and benefiting joints. It is used to treat common cold, wind-cold, headache, anhidrosis, arthralgia due to wind-cold-dampness, stiff neck, soreness of joints, edema due to wind-damp, carbuncle, sore and toxin.
Red peony root: cold in nature, bitter and sour in taste, entering liver and spleen meridians. Has the effects of clearing heat, cooling blood, promoting blood circulation and removing blood stasis. It can be used for treating heat entering nutrient-blood, fever with macula, blood heat hematemesis and epistaxis, amenorrhea due to blood stagnation, dysmenorrhea, abdominal mass, traumatic injury, swelling and pain due to blood stasis, and pyocutaneous disease due to heat toxin.
Rhizoma drynariae: it is warm in nature and bitter in taste, entering liver and kidney meridians. Has the functions of invigorating kidney, promoting blood circulation and stopping bleeding. It is used to treat chronic diarrhea due to kidney deficiency, lumbago, rheumatalgia, toothache, tinnitus, traumatic injury, bone injury, appendicitis, alopecia areata, and clavus.
Raspberry: it is warm in nature, sweet and sour in flavor, and enters kidney and bladder meridians. Has the effects of nourishing liver and kidney, reducing urination, supporting yang, controlling nocturnal emission and improving eyesight. For impotence, seminal emission, scanty urine, enuresis, consumptive disease and dim eyesight.
Red sage root: it is cold in nature and bitter in taste, and enters heart and liver meridians. Has the effects of removing blood stasis, relieving pain, promoting blood circulation, dredging channels, clearing away heart-fire and relieving restlessness. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal mass, thoracico-abdominal pain, arthralgia due to heat, pyocutaneous disease, swelling and pain, vexation, and insomnia; hepatosplenomegaly, angina pectoris.
Wild jujube seed: neutral in nature, sweet and sour in flavor, entering liver, gallbladder and heart meridians. Has the functions of nourishing liver, calming heart, arresting sweating and promoting the production of body fluid. Can be used for treating vexation, insomnia, palpitation, dreaminess, asthenia, hyperhidrosis, body fluid deficiency, and thirst.
Bupleurum root: it is cold in nature, pungent and bitter in flavor, and enters liver and gallbladder meridians. Has the effects of relieving exterior syndrome and interior syndrome, invigorating yang, dispersing stagnated liver qi, and regulating menstruation. Can be used for treating common cold, upper respiratory infection, malaria, alternating chills and fever, costalgia, hepatitis, biliary tract infection, cholecystitis, menoxenia, and proctoptosis.
Herba artemisiae scopariae: it is cold in nature, pungent and bitter in flavor, and enters spleen, stomach, liver and gallbladder meridians. Has the effects of clearing away damp-heat and eliminating jaundice. Can be used for treating jaundice, oliguria, eczema, and pruritus; infectious icteric hepatitis.
Cacumen biotae: pleurotus ostreatus leaf, it is cold in nature and bitter and astringent in taste. It enters lung meridian, liver meridian and spleen meridian. Has the functions of cooling blood, stopping bleeding, dispelling wind-damp and dispersing swelling and toxin. It is used to treat hematemesis, epistaxis, hematuria, dysentery, intestinal wind, metrorrhagia, rheumatalgia, bacillary dysentery, hypertension, cough, erysipelas, mumps, and scald.
Winter mulberry leaf: cold in nature, sweet and bitter in taste. It enters lung and liver meridians. Has the effects of dispelling pathogenic wind, clearing heat, cooling blood and improving eyesight. It is indicated for fever due to wind-warm pathogen, headache, conjunctival congestion, thirst, cough due to lung heat, wind arthralgia, urticaria, and edema of lower limbs.
Asarum: it is warm in nature and pungent in flavor, entering lung and kidney meridians. Has the functions of expelling wind, dispelling cold, promoting diuresis and inducing resuscitation. It is indicated for wind-cold headache, nasosinusitis, toothache, phlegm-fluid cough, wind-damp arthralgia.
Chicken kidney ginseng: warm in nature, sweet and bitter in taste. Has the effects of tonifying kidney and benefiting qi. Can be used for treating lumbago due to kidney deficiency, nephritis, hernia, and neurosis.
Centipede: it is warm in nature and pungent in flavor, entering liver meridian. Has the effects of dispelling pathogenic wind, arresting convulsion, counteracting toxic substances and resolving hard mass. It is used to treat apoplexy, epilepsy, tetanus, pertussis, scrofula, tuberculosis, tumor, skin and external diseases, tinea, alopecia areata, anal fistula and scald.
The traditional Chinese medicine raw materials in the oral medicine can be combined with a pharmaceutically acceptable carrier to prepare a conventional preparation for oral use, such as: capsule, oral liquid, powder or granule, preferably made into watered pill or honeyed pill.
The specific method for preparing the traditional Chinese medicine raw materials into water pills or honeyed pills comprises the following steps:
(1) weighing the components according to the proportion of the medicinal components;
(2) parching the centipedes in the step (1) to dry and drying other medicinal materials for later use;
(3) grinding all the medicinal materials in the step (2) into medicinal powder, adding cold boiled water or honey to prepare water pills or honeyed pills, and drying to obtain the hair growing pills.
The external medicine comprises the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of rhizoma drynariae, 10-30 parts of scorpion, 10-20 parts of asarum and 2-3 parts of centipede; the effect is better when the external medicine is used together with the hair growing pill.
Scorpion: neutral in nature and pungent in flavor, enter liver meridian. Has the effects of calming endogenous wind, relieving spasm, counteracting toxic pathogen, resolving hard mass, dredging collaterals and relieving pain. Can be used for treating infantile convulsion, spasm, facial distortion due to apoplexy, hemiplegia, tetanus, rheumatism, headache, pyocutaneous disease, and lymphoid tuberculosis.
The rhizoma drynariae, the scorpion, the asarum and the centipede are used in a matching way, so that the effects of promoting blood circulation and removing obstruction in channels are achieved, the effective components can permeate into subcutaneous tissues, the subcutaneous blood circulation of the head is promoted, the nutrition required by hair growth is supplemented, and the effects of nourishing, protecting and growing hair are achieved.
Soaking rhizoma drynariae, scorpion, asarum and centipede in 500-1000 ml of 70-80% ethanol for 3-7 days to obtain a leaching solution, namely the externally applied agent for treating alopecia; preferably, the concentration of ethanol is 75%.
The usage and dosage are as follows:
hair growth pills: orally administered 3 times a day, 1 time each in the morning, noon and evening, 9g each time, with warm boiled water after meal; 1 month is 1 course of treatment, 3 courses of treatment are taken for growing hair, and 5 courses of treatment are taken for growing hair.
The external medicine comprises: directly applying on scalp, applying once every 3 days, and mixing with hair growth promoting pill.
Contraindications during the administration period are: the fasting wine and tobacco are pungent and hot substances, and keep the mood stable.
The present invention will be further described with reference to the following specific examples. The following examples are illustrative only and are not to be construed as limiting the invention.
Example 1:
the oral medicine in the medicine for treating alopecia provided by the embodiment comprises the following raw materials:
240g of tortoise plastron, 240g of turtle shell, 240g of prepared fleece flower root, 180g of radix rehmanniae recen, 180g of prepared rehmannia root, 180g of medlar, 180g of cornus officinalis, 180g of glossy privet fruit, 180g of angelica, 180g of mulberry, 180g of gastrodia elata, 156g of dodder, 156g of eclipta alba, 156g of rhizoma cyperi, 156g of cortex dictamni, 156g of notopterygium root, 156g of red paeony root, 156g of rhizoma drynariae, 156g of raspberry, 156g of salvia miltiorrhiza, 156g of spina date seed, 120g of radix bupleuri, 120g of oriental wormwood, 120g of cacumen biotae, 120g of winter mulberry leaf, 90g of asarum.
The specific method for preparing the traditional Chinese medicine raw materials into water pills or honeyed pills comprises the following steps:
(1) weighing the medicinal materials according to the weight of the medicinal materials for later use;
(2) parching the centipedes in the step (1) to dry and drying other medicinal materials for later use;
(3) grinding all the medicinal materials in the step (2) into medicinal powder, adding cold boiled water or honey to prepare water pills or honeyed pills, and drying to obtain the hair growing pills.
The external medicine comprises the following traditional Chinese medicine raw materials in parts by weight: 20g of rhizoma drynariae, 20g of scorpion, 15g of asarum and 3g of centipede.
Soaking rhizoma drynariae, scorpion, asarum and centipede in 500ml of 75% ethanol for 3-7 days to obtain a leaching solution, namely the externally applied medicine for treating alopecia.
Example 2:
the oral medicine in the medicine for treating alopecia provided by the embodiment comprises the following raw materials:
200g of tortoise plastron, 170g of turtle shell, 170g of prepared fleece flower root, 160g of radix rehmanniae, 160g of prepared rehmannia root, 150g of medlar, 150g of cornus officinalis, 135g of glossy privet fruit, 130g of angelica, 130g of mulberry, 125g of gastrodia elata, 120g of dodder, 118g of eclipta alba, 118g of rhizoma cyperi, 104g of cortex dictamni, 104g of notopterygium root, 104g of red paeony root, 104g of rhizoma drynariae, 104g of raspberry, 104g of salvia miltiorrhiza, 100g of spina date seed, 95g of radix bupleuri, 95g of oriental wormwood, 95g of cacumen biotae, 95g of winter mulberry leaf, 60g of asarum, 45 g.
The composition of the external medicament, the hair growth promoting pills and the preparation method of the external medicament in the embodiment have the same process steps as the embodiment 1.
Example 3:
the oral medicine in the medicine for treating alopecia provided by the embodiment comprises the following raw materials:
280g of tortoise plastron, 250g of turtle shell, 250g of prepared fleece flower root, 230g of radix rehmanniae recen, 230g of prepared rehmannia root, 210g of medlar, 210g of dogwood fruit, 205g of glossy privet fruit, 200g of angelica, 200g of mulberry, 185g of gastrodia elata, 180g of dodder, 175g of eclipta alba, 175g of rhizoma cyperi, 160g of cortex dictamni, 160g of notopterygium root, 160g of red paeony root, 160g of rhizoma drynariae, 160g of raspberry, 160g of salvia miltiorrhiza, 160g of spina date seed, 130g of radix bupleuri, 130g of oriental wormwood, 130g of cacumen biotae, 130g of winter mulberry leaf, 100g of asarum.
The composition of the external medicament, the hair growth promoting pills and the preparation method of the external medicament in the embodiment have the same process steps as the embodiment 1.
Example 4:
the oral medicine in the medicine for treating alopecia provided by the embodiment comprises the following raw materials:
40g of tortoise plastron, 400g of turtle shell, 400g of prepared fleece flower root, 30g of radix rehmanniae, 30g of prepared rehmannia root, 300g of medlar, 300g of cornus officinalis, 300g of glossy privet fruit, 300g of angelica, 300g of mulberry, 300g of rhizoma gastrodiae, 26g of semen cuscutae, 26g of eclipta alba, 26g of rhizoma cyperi, 260g of cortex dictamni, 260g of notopterygium root, 260g of red paeony root, 260g of rhizoma drynariae, 260g of raspberry, 260g of salvia miltiorrhiza, 260g of spina date seed, 200g of radix bupleuri, 20g of oriental wormwood, 20g of cacumen biotae, 200g of winter mulberry leaf, 150g of asarum.
The composition of the external medicament, the hair growth promoting pills and the preparation method of the external medicament in the embodiment have the same process steps as the embodiment 1.
Example 5:
the oral medicine in the medicine for treating alopecia provided by the embodiment comprises the following raw materials:
400g of tortoise plastron, 40g of turtle shell, 40g of prepared fleece flower root, 300g of radix rehmanniae, 300g of prepared rehmannia root, 30g of medlar, 30g of cornus officinalis, 30g of glossy privet fruit, 30g of angelica, 30g of mulberry, 30g of gastrodia elata, 260g of semen cuscutae, 260g of eclipta alba, 260g of rhizoma cyperi, 26g of cortex dictamni, 26g of notopterygium root, 26g of red paeony root, 26g of rhizoma drynariae, 26g of raspberry, 26g of salvia miltiorrhiza, 26g of spina date seed, 20g of radix bupleuri, 200g of oriental wormwood, 200g of cacumen biotae, 20g of winter mulberry leaf, 15g of asarum.
The composition of the external medicament, the hair growth promoting pills and the preparation method of the external medicament in the embodiment have the same process steps as the embodiment 1.
Example 6:
the raw material composition of the oral medicine in the medicine for treating alopecia and the preparation process steps of the medicine are the same
Example 1, the difference is in the composition of the external preparation.
The external medicine comprises the following traditional Chinese medicine raw materials in parts by weight: 30g of rhizoma drynariae, 10g of scorpion, 10g of asarum and 3g of centipede.
Soaking rhizoma drynariae, scorpion, asarum and centipede in 500ml of 70% ethanol for 3-7 days to obtain a leaching solution, namely the externally applied medicine for treating alopecia.
Example 7:
the raw material composition of the oral medicine in the medicine for treating alopecia and the preparation process steps of the medicine are the same
Example 1, the difference is in the composition of the external preparation.
The external medicine comprises the following traditional Chinese medicine raw materials in parts by weight: 10g of drynaria rhizome, 30g of scorpion, 20g of asarum and 2g of centipede.
Soaking rhizoma drynariae, scorpion, asarum and centipede in 500ml of 80% ethanol for 3-7 days to obtain a leaching solution, namely the externally applied medicine for treating alopecia.
Clinical research
1. Case data: 240 patients diagnosed with seborrheic alopecia, alopecia areata or alopecia totalis were selected, 182 in men and 58 in women. The age is 30-59 years, the average age is 45 years, the course of disease is 3 months to 5 years, and the average course of disease is 10.4 months. Adopts the layered random distribution, takes the age, the sex and the disease condition degree as the layering factors, and then randomly divides the selected patients into 1 treatment group, 2 treatment groups, 3 treatment groups, 4 treatment groups, 5 treatment groups, 6 treatment groups, 7 treatment groups and a control group. The patients in 8 groups have no significant difference and are comparable through statistical analysis on sex, age, disease course, disease degree and other clinical characteristics.
2. The treatment method comprises the following steps:
treatment groups: the treatment groups 1-7 are orally taken with the hair growing pills of the embodiments 1-7 sequentially, 3 times a day, 1 time in the morning, noon and evening, 9g each time, and the pills are taken with warm boiled water after meals; 1 course of treatment is 1 month. Simultaneously, the external medicine is matched with the hair growing pill for use, and is directly smeared on the scalp once every 3 days.
Control group: a blank placebo is taken, and the hair is washed with a shampoo for treating alopecia on the market every 3 days, wherein 1 month is 1 treatment course.
The treatment results are counted after 5 treatment courses of clinical observation. During the treatment period, the treated group and the control group are fast on the hot substances of the tobacco and the wine, and the mood is kept stable.
3. And (3) judging the curative effect:
and (3) curing: the alopecia phenomenon is reduced, and the hair on the top of the head is thick;
improvement: the alopecia phenomenon is reduced, and the hair on the top of the head is increased;
and (4) invalidation: the hair loss phenomenon is not reduced, and the hair on the top of the head is sparse.
4. Therapeutic effects
After 5 courses of clinical observation, the results are shown in table 1.
TABLE 1 comparison of the efficacy of the control group in the treatment groups
Figure BDA0001570654810000081
Figure BDA0001570654810000091
As can be seen from Table 1, after 5 courses of treatment, the total effective rate of the treatment group is up to 90%, and can reach 100% at most, while the total effective rate of the control group is 46.67%, which indicates that the total effective rate of the treatment group is obviously superior to that of the control group. In addition, as can be seen from table 1, the medicine prepared by the invention can safely and effectively treat alopecia, wherein the effect of treating the groups 1, 6 and 7 is the best, the effect of treating the groups 2 and 3 is the second, the effect of treating the groups 4 and 5 is slightly poorer than the effect of treating the groups 1 to 3 and 6 to 7, and the effect of treating the groups 1, 6 and 7 on the medicine effect of the medicine for treating alopecia is not obviously different when the bone patch in the external medicine is 10 to 30g, the scorpion is 10 to 30g, the asarum is 10 to 20 and the centipede is 2 to 3 g.
The above-described embodiments of the present invention should not be construed as limiting the scope of the present invention. Any other corresponding changes and modifications made according to the technical idea of the present invention should be included in the protection scope of the claims of the present invention.

Claims (7)

1. The medicine for treating alopecia is characterized by comprising an oral medicine and an external medicine, wherein the oral medicine comprises the following traditional Chinese medicine raw materials in parts by weight: 40-400 parts of tortoise plastron, 40-400 parts of turtle shell, 40-400 parts of prepared fleece-flower root, 30-300 parts of radix rehmanniae, 30-300 parts of prepared rehmannia root, 30-300 parts of medlar, 30-300 parts of cornus officinalis, 30-300 parts of glossy privet fruit, 30-300 parts of angelica, 30-300 parts of mulberry, 30-300 parts of rhizoma gastrodiae, 26-260 parts of dodder, 26-260 parts of eclipta alba, 26-260 parts of rhizoma cyperi, 26-260 parts of cortex dictamni, 26-260 parts of notopterygium root, 26-260 parts of red paeony root, 26-260 parts of rhizoma drynariae, 26-260 parts of raspberry, 26-260 parts of salvia miltiorrhiza, 26-260 parts of spina date seed, 20-200 parts of radix bupleuri, 20-200 parts of oriental wormwood, 20-200 parts of cacumen biotae, 20-200 parts of winter mulberry leaf, 15-150 parts of asarum, 10-100; the traditional Chinese medicine raw materials of the external medicine comprise the following components in parts by weight: 10-30 parts of rhizoma drynariae, 10-30 parts of scorpion, 10-20 parts of asarum and 2-3 parts of centipede.
2. The medicament for treating alopecia according to claim 1, wherein the oral medicament comprises the following raw materials in parts by weight: 200-280 parts of tortoise plastron, 170-250 parts of turtle shell, 170-250 parts of prepared fleece-flower root, 160-230 parts of radix rehmanniae recen, 160-230 parts of prepared rehmannia root, 150-210 parts of medlar, 150-210 parts of cornus officinalis, 135-205 parts of glossy privet fruit, 130-200 parts of angelica, 130-200 parts of mulberry, 125-185 parts of tall gastrodia tuber, 120-180 parts of south dodder seed, 118-175 parts of eclipta alba, 118-175 parts of nutgrass galingale rhizome, 104-160 parts of dittany bark, 104-160 parts of notopterygium root, 104-160 parts of red paeony root, 104-160 parts of drynaria rhizome, 104-160 parts of raspberry, 104-160 parts of red-rooted salvia root, 100-160 parts of spina date seed, 95-130 parts of Chinese thorowax root, 95-130 parts of oriental wormwood, 95-130 parts of Chinese arborvitae twig, 95-130 parts of winter mulberry.
3. The medicament for treating alopecia according to claim 1, wherein the oral medicament comprises the following raw materials by weight: tortoise plastron: turtle shell: radix polygoni multiflori preparata: dried rehmannia root: prepared rehmannia root: medlar: cornus officinalis: glossy privet fruit: chinese angelica: mulberry: gastrodia elata: dodder seed: eclipta alba: rhizoma cyperi: and (3) preparing cortex dictamni: notopterygium root: red peony root: rhizoma drynariae: raspberry: red sage root: wild jujube seed: bupleurum root: herba artemisiae scopariae: cacumen biotae: winter mulberry leaf: asarum: chicken kidney ginseng: the centipede is 4: 4: 4: 3: 3: 3: 3: 3: 3: 3: 3: 2.6: 2.6: 2.6: 2.6: 2.6: 2.6: 2.6: 2.6: 2.6: 2.6: 2: 2: 2: 2: 1.5: 1: 0.8.
4. the agent for treating alopecia according to any one of claims 1 to 3, wherein the raw materials of the oral drug can be combined with a carrier to prepare a pill, a capsule, an oral liquid, a powder or a granule.
5. The medicine for treating alopecia according to claim 4, wherein the traditional Chinese medicine raw materials in the oral medicine are prepared into water pills or honey pills for administration by water or honey.
6. The medicine for treating alopecia according to claim 1, wherein the Chinese medicinal materials for external use are soaked in ethanol for 3-7 days, and the obtained leachate is ready for use.
7. The agent for treating alopecia according to claim 6, wherein the concentration of ethanol is 70-80%.
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